LOCUS       DAFEML010000001       129089 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFEML010000001
VERSION     DAFEML010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 129089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 129089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..129089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.001"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="LP468_000001"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="LP468_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL2079572.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="LP468_000002"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="LP468_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL2079573.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="LP468_000003"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="LP468_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL2079574.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="LP468_000004"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="LP468_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL2079575.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="LP468_000005"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="LP468_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL2079576.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="LP468_000006"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="LP468_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL2079577.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="LP468_000007"
     CDS             complement(8558..9028)
                     /locus_tag="LP468_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL2079578.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="LP468_000008"
     CDS             complement(9074..9499)
                     /locus_tag="LP468_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL2079579.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="LP468_000009"
     CDS             complement(9566..9835)
                     /locus_tag="LP468_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL2079580.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="LP468_000010"
     CDS             complement(9846..11441)
                     /locus_tag="LP468_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2079581.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="LP468_000011"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="LP468_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL2079582.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /locus_tag="LP468_000012"
     CDS             complement(14994..15554)
                     /locus_tag="LP468_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL2079583.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="LP468_000013"
     CDS             15907..16881
                     /locus_tag="LP468_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL2079584.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="LP468_000014"
     CDS             17051..18451
                     /locus_tag="LP468_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL2079585.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="LP468_000015"
     CDS             complement(18529..19251)
                     /locus_tag="LP468_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2079586.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="LP468_000016"
     CDS             complement(19330..19836)
                     /locus_tag="LP468_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2079587.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="LP468_000017"
     CDS             19959..21758
                     /locus_tag="LP468_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL2079588.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21826..23400)
                     /locus_tag="LP468_000018"
     CDS             complement(21826..23400)
                     /locus_tag="LP468_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2079589.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="LP468_000019"
     CDS             complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="LP468_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL2079590.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="LP468_000020"
     CDS             complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="LP468_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL2079591.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25177..25815)
                     /locus_tag="LP468_000021"
     CDS             complement(25177..25815)
                     /locus_tag="LP468_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL2079592.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLEGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25816..26466)
                     /locus_tag="LP468_000022"
     CDS             complement(25816..26466)
                     /locus_tag="LP468_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL2079593.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="LP468_000023"
     CDS             complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="LP468_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL2079594.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="LP468_000024"
     CDS             complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="LP468_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL2079595.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29609..30349)
                     /locus_tag="LP468_000025"
     CDS             complement(29609..30349)
                     /locus_tag="LP468_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL2079596.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="LP468_000026"
     CDS             complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="LP468_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL2079597.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31720..32658)
                     /locus_tag="LP468_000027"
     CDS             complement(31720..32658)
                     /locus_tag="LP468_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL2079598.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKKLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32651..33142)
                     /gene="def"
                     /locus_tag="LP468_000028"
     CDS             complement(32651..33142)
                     /gene="def"
                     /locus_tag="LP468_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2079599.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33157..35565)
                     /gene="priA"
                     /locus_tag="LP468_000029"
     CDS             complement(33157..35565)
                     /gene="priA"
                     /locus_tag="LP468_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL2079600.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35818..36123)
                     /locus_tag="LP468_000030"
     CDS             complement(35818..36123)
                     /locus_tag="LP468_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2079601.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="LP468_000031"
     CDS             complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="LP468_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL2079602.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37229..37513)
                     /locus_tag="LP468_000032"
     CDS             complement(37229..37513)
                     /locus_tag="LP468_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079603.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37531..38421)
                     /locus_tag="LP468_000033"
     CDS             complement(37531..38421)
                     /locus_tag="LP468_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL2079604.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38441..38659)
                     /locus_tag="LP468_000034"
     CDS             complement(38441..38659)
                     /locus_tag="LP468_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL2079605.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38629..40329)
                     /locus_tag="LP468_000035"
     CDS             complement(38629..40329)
                     /locus_tag="LP468_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL2079606.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40596..41369
                     /locus_tag="LP468_000036"
     CDS             40596..41369
                     /locus_tag="LP468_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079607.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="LP468_000037"
     CDS             complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="LP468_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL2079608.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42085..42187)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42193..43164)
                     /locus_tag="LP468_000038"
     CDS             complement(42193..43164)
                     /locus_tag="LP468_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2079609.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="LP468_000039"
     CDS             complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="LP468_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL2079610.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45134..45952)
                     /gene="purR"
                     /locus_tag="LP468_000040"
     CDS             complement(45134..45952)
                     /gene="purR"
                     /locus_tag="LP468_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL2079611.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46119..46943)
                     /locus_tag="LP468_000041"
     CDS             complement(46119..46943)
                     /locus_tag="LP468_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2079612.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46916..47596)
                     /locus_tag="LP468_000042"
     CDS             complement(46916..47596)
                     /locus_tag="LP468_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2079613.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47619..48557)
                     /locus_tag="LP468_000043"
     CDS             complement(47619..48557)
                     /locus_tag="LP468_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL2079614.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48802..49665)
                     /locus_tag="LP468_000044"
     CDS             complement(48802..49665)
                     /locus_tag="LP468_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL2079615.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="LP468_000045"
     CDS             complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="LP468_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2079616.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52521..53327
                     /gene="proC"
                     /locus_tag="LP468_000046"
     CDS             52521..53327
                     /gene="proC"
                     /locus_tag="LP468_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL2079617.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53406..54962)
                     /gene="rny"
                     /locus_tag="LP468_000047"
     CDS             complement(53406..54962)
                     /gene="rny"
                     /locus_tag="LP468_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL2079618.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55373..56422)
                     /gene="recA"
                     /locus_tag="LP468_000048"
     CDS             complement(55373..56422)
                     /gene="recA"
                     /locus_tag="LP468_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL2079619.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56531..57772)
                     /locus_tag="LP468_000049"
     CDS             complement(56531..57772)
                     /locus_tag="LP468_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL2079620.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="LP468_000050"
     CDS             complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="LP468_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL2079621.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58799..59722)
                     /locus_tag="LP468_000051"
     CDS             complement(58799..59722)
                     /locus_tag="LP468_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2079622.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60461..61747)
                     /locus_tag="LP468_000052"
     CDS             complement(60461..61747)
                     /locus_tag="LP468_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2079623.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61740..63008)
                     /locus_tag="LP468_000053"
     CDS             complement(61740..63008)
                     /locus_tag="LP468_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2079624.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63260..63721
                     /gene="mscL"
                     /locus_tag="LP468_000054"
     CDS             63260..63721
                     /gene="mscL"
                     /locus_tag="LP468_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL2079625.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63780..64226)
                     /locus_tag="LP468_000055"
     CDS             complement(63780..64226)
                     /locus_tag="LP468_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2079626.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64319..64564)
                     /locus_tag="LP468_000056"
     CDS             complement(64319..64564)
                     /locus_tag="LP468_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL2079627.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64679..65257)
                     /locus_tag="LP468_000057"
     CDS             complement(64679..65257)
                     /locus_tag="LP468_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2079628.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65334..65864)
                     /locus_tag="LP468_000058"
     CDS             complement(65334..65864)
                     /locus_tag="LP468_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL2079629.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="LP468_000059"
     CDS             complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="LP468_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL2079630.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66721..67116)
                     /locus_tag="LP468_000060"
     CDS             complement(66721..67116)
                     /locus_tag="LP468_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL2079631.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67113..68525)
                     /locus_tag="LP468_000061"
     CDS             complement(67113..68525)
                     /locus_tag="LP468_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL2079632.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68522..69058)
                     /gene="cysE"
                     /locus_tag="LP468_000062"
     CDS             complement(68522..69058)
                     /gene="cysE"
                     /locus_tag="LP468_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL2079633.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69144..69383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69380..70840)
                     /locus_tag="LP468_000063"
     CDS             complement(69380..70840)
                     /locus_tag="LP468_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL2079634.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71010..72167)
                     /locus_tag="LP468_000064"
     CDS             complement(71010..72167)
                     /locus_tag="LP468_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL2079635.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72201..73571)
                     /gene="radA"
                     /locus_tag="LP468_000065"
     CDS             complement(72201..73571)
                     /gene="radA"
                     /locus_tag="LP468_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL2079636.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73634..74161)
                     /locus_tag="LP468_000066"
     CDS             complement(73634..74161)
                     /locus_tag="LP468_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL2079637.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74391..75197
                     /gene="proB"
                     /locus_tag="LP468_000067"
     CDS             74391..75197
                     /gene="proB"
                     /locus_tag="LP468_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL2079638.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75194..76441
                     /locus_tag="LP468_000068"
     CDS             75194..76441
                     /locus_tag="LP468_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL2079639.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76517..76861
                     /locus_tag="LP468_000069"
     CDS             76517..76861
                     /locus_tag="LP468_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079640.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76978..77304)
                     /locus_tag="LP468_000070"
     CDS             complement(76978..77304)
                     /locus_tag="LP468_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079641.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77919..79121)
                     /locus_tag="LP468_000071"
     CDS             complement(77919..79121)
                     /locus_tag="LP468_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2079642.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79238..79753
                     /locus_tag="LP468_000072"
     CDS             79238..79753
                     /locus_tag="LP468_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2079643.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79952..80398)
                     /locus_tag="LP468_000073"
     CDS             complement(79952..80398)
                     /locus_tag="LP468_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2079644.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="LP468_000074"
     CDS             complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="LP468_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2079645.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82277..82906)
                     /locus_tag="LP468_000075"
     CDS             complement(82277..82906)
                     /locus_tag="LP468_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2079646.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82890..83354)
                     /locus_tag="LP468_000076"
     CDS             complement(82890..83354)
                     /locus_tag="LP468_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2079647.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83841..85109)
                     /locus_tag="LP468_000077"
     CDS             complement(83841..85109)
                     /locus_tag="LP468_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2079648.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85340..86077)
                     /locus_tag="LP468_000078"
     CDS             complement(85340..86077)
                     /locus_tag="LP468_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2079649.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86144..86713)
                     /locus_tag="LP468_000079"
     CDS             complement(86144..86713)
                     /locus_tag="LP468_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2079650.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86841..87713
                     /locus_tag="LP468_000080"
     CDS             86841..87713
                     /locus_tag="LP468_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2079651.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88055..88927
                     /locus_tag="LP468_000081"
     CDS             88055..88927
                     /locus_tag="LP468_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2079652.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88924..90882
                     /locus_tag="LP468_000082"
     CDS             88924..90882
                     /locus_tag="LP468_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2079653.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91214..92065)
                     /locus_tag="LP468_000083"
     CDS             complement(91214..92065)
                     /locus_tag="LP468_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2079654.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92188..92655
                     /locus_tag="LP468_000084"
     CDS             92188..92655
                     /locus_tag="LP468_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL2079655.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92918..93400)
                     /locus_tag="LP468_000085"
     CDS             complement(92918..93400)
                     /locus_tag="LP468_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2079656.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93500..94363)
                     /locus_tag="LP468_000086"
     CDS             complement(93500..94363)
                     /locus_tag="LP468_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2079657.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94961..95836
                     /locus_tag="LP468_000087"
     CDS             94961..95836
                     /locus_tag="LP468_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079658.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95981..96133)
                     /locus_tag="LP468_000088"
                     /pseudo
     CDS             complement(95981..96133)
                     /locus_tag="LP468_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96401..97732)
                     /locus_tag="LP468_000089"
     CDS             complement(96401..97732)
                     /locus_tag="LP468_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2079659.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97881..98594)
                     /locus_tag="LP468_000090"
     CDS             complement(97881..98594)
                     /locus_tag="LP468_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2079660.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98769..100193
                     /locus_tag="LP468_000091"
     CDS             98769..100193
                     /locus_tag="LP468_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2079661.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100492..101199
                     /locus_tag="LP468_000092"
     CDS             100492..101199
                     /locus_tag="LP468_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2079662.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101186..101509
                     /locus_tag="LP468_000093"
     CDS             101186..101509
                     /locus_tag="LP468_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2079663.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101598..102635)
                     /locus_tag="LP468_000094"
     CDS             complement(101598..102635)
                     /locus_tag="LP468_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2079664.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102956..103939)
                     /locus_tag="LP468_000095"
     CDS             complement(102956..103939)
                     /locus_tag="LP468_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL2079665.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104354..105124)
                     /locus_tag="LP468_000096"
     CDS             complement(104354..105124)
                     /locus_tag="LP468_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079666.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105117..106052)
                     /locus_tag="LP468_000097"
     CDS             complement(105117..106052)
                     /locus_tag="LP468_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079667.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106368..108017)
                     /locus_tag="LP468_000098"
     CDS             complement(106368..108017)
                     /locus_tag="LP468_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2079668.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108134..110737)
                     /locus_tag="LP468_000099"
     CDS             complement(108134..110737)
                     /locus_tag="LP468_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2079669.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110749..111798)
                     /locus_tag="LP468_000100"
     CDS             complement(110749..111798)
                     /locus_tag="LP468_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBL2079670.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111824..112138)
                     /locus_tag="LP468_000101"
     CDS             complement(111824..112138)
                     /locus_tag="LP468_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBL2079671.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112154..112600)
                     /locus_tag="LP468_000102"
     CDS             complement(112154..112600)
                     /locus_tag="LP468_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2079672.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112601..114523)
                     /locus_tag="LP468_000103"
     CDS             complement(112601..114523)
                     /locus_tag="LP468_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBL2079673.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114735..115631)
                     /locus_tag="LP468_000104"
     CDS             complement(114735..115631)
                     /locus_tag="LP468_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2079674.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115624..116304)
                     /locus_tag="LP468_000105"
     CDS             complement(115624..116304)
                     /locus_tag="LP468_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2079675.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116305..117087)
                     /locus_tag="LP468_000106"
     CDS             complement(116305..117087)
                     /locus_tag="LP468_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079676.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117080..117997)
                     /locus_tag="LP468_000107"
     CDS             complement(117080..117997)
                     /locus_tag="LP468_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2079677.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118161..118484)
                     /locus_tag="LP468_000108"
     CDS             complement(118161..118484)
                     /locus_tag="LP468_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079678.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            119272..122499
                     /gene="fss3"
                     /locus_tag="LP468_000109"
     CDS             119272..122499
                     /gene="fss3"
                     /locus_tag="LP468_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL2079679.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122612..122926
                     /locus_tag="LP468_000110"
     CDS             122612..122926
                     /locus_tag="LP468_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2079680.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122939..123313
                     /locus_tag="LP468_000111"
     CDS             122939..123313
                     /locus_tag="LP468_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2079681.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123323..123658
                     /locus_tag="LP468_000112"
     CDS             123323..123658
                     /locus_tag="LP468_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL2079682.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123741..125081
                     /locus_tag="LP468_000113"
     CDS             123741..125081
                     /locus_tag="LP468_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2079683.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125159..125833
                     /locus_tag="LP468_000114"
     CDS             125159..125833
                     /locus_tag="LP468_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2079684.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125826..125990
                     /locus_tag="LP468_000115"
     CDS             125826..125990
                     /locus_tag="LP468_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079685.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126066..127208
                     /gene="dcm"
                     /locus_tag="LP468_000116"
                     /pseudo
     CDS             126066..127208
                     /gene="dcm"
                     /locus_tag="LP468_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127198..127488
                     /locus_tag="LP468_000117"
     CDS             127198..127488
                     /locus_tag="LP468_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079686.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127747..128931
                     /locus_tag="LP468_000118"
     CDS             127747..128931
                     /locus_tag="LP468_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2079687.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128928..129065
                     /locus_tag="LP468_000119"
     CDS             128928..129065
                     /locus_tag="LP468_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL2079688.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        37158 a        26997 c        23256 g        41678 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga actgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttgattaat cattcttaca tgctgacagc
    21841 aaagtcaggg gcaaaccatt gaactgaacc aacttttacg ctttcgcctg gttgaggagc
    21901 atggatatat tgtcctccgc ctaaagcaat cgctacgtgg taagttccgc cttgtgaccc
    21961 ccagaataac aagtctccag cttttgcttg agaaactgaa atttttgttc cagctgattc
    22021 ttgaggaact gtccaaccac cgatgtcacg accagttact tgcatgtaaa catagcgtgt
    22081 gaaccctgag cagtcaaagc cacttggatc tttaccgccc caaacatatg gagtaccaat
    22141 atatttgtaa gcttctgcta cgattgctgc accattcaca cttccagaag gagctggagc
    22201 aggtgttaca ggttttggtt gttcaggtgt tggtgttggc gttggagccg gagtactact
    22261 tcctgtgccg tttcctgtat caacactttg atctgttgat ggtgttgtag gcgcaggtgt
    22321 tgttgattct tctgttgttg aagattcagg cactgttgtt gattcttctg ttgctgaaga
    22381 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcgctgttg ttgattcttc
    22441 tgttgctgaa gattcaggcg ctgttgattc ttctgttgaa gattcaggtg ttgttgattc
    22501 ttctgttgct gaagattgtg tagctgatga tgattcttca gtcattgaag attgtgtagc
    22561 tgatgattct tctgttgctg agctttgtgc agtagatgaa gcttgagtag cttgtgcttc
    22621 agcctctgct tgttcgcgtg cttctttttc agctttttct tgtgcagctt gttgacgagc
    22681 ttgttctgct agacgttgtt gttcacgaat acgagcttgc tctgcttcag cttctgcttt
    22741 ttgacggttc aagtcagctt tcttgtcttc agcagttgct tgttcagcag ctaatgaagt
    22801 tttcagtacg ttcaaatcag cttgtttaga taaaagatcg cctttttgag attccaaagc
    22861 agcttggttt tcagctaatt cttttagttt agcatcgttt tcagcttttt tgtcttctac
    22921 agctttttta tcttgttttt gttgttccat caagtcgttg tttgctttta ccatcgttgt
    22981 cattgcttga acgcgtccaa tagcatctgc taatgaatca gcattcaata cagcatcgat
    23041 gtagtttgag cttgtgttgc ttacttgtgc ttcgcgtgct tgtttttgga ttgtatcttc
    23101 acgtttttca atacgttctt gtaaatctgc aatgtctttt actaattgtg cagattcttg
    23161 acgcaatgta tcttgttttg ctaataggtc ttgtgcttgt gtgttgattt cagaaacttg
    23221 gctttctaag gcatcgattt gtgattgtgc atctgcttgt tgatttttca agtctgcaat
    23281 cttttgatct tgctgttgta tctgagaatc aaaatcgtcc gccgcggcag cgatcggtga
    23341 tgctacggca gtcaaggtca ttgaacatac cattactgct gatattaaac tctttttcac
    23401 tcttcattcc tccgactggc ttaatttaat aaatatctaa atatatttaa gtctttctta
    23461 acgatataaa aattgtacca tagcagtgtg tcaacgatat aatagttatg ttacaaaaat
    23521 gtttcaaaac aacttttaaa aatgacaaaa ctgttcgttt cagaaaatga tcatgaaaaa
    23581 gccgcgttaa gtctagcatt tcttaagata acaacgattc tttttcgctt tcgacctaaa
    23641 aataaaaaaa gaaattattc atcactgaat aatttcttaa agggaaaaat gaataataca
    23701 aatataatca tgttcaacag cagtgtaggt cctaaaaacc ttgtaataaa atacgtgtta
    23761 tttactactg ctaatttaaa aatcaactgg accaccatcg taaacaattc ataacccgtg
    23821 acaaagatga tcatactgaa aaattcagta aagatgttga catggataac gtctttcatt
    23881 acatacatca accatacaat taaagggaga gctactgcat agataccgat aacgccaata
    23941 tagtaagcgt catagatagc cccgagaaca atcgtggtaa tcagtaaata acgtttttca
    24001 aacgccatac tgcaacataa taatgccaat atcagaaagt gggcatttga catataggtg
    24061 cctttcgacc actcccctag cattcttgtt aaatgaccat ctatcaacat caaaaagaac
    24121 aaaacgattg gcagatagta cttcattgtt tctttcttca acatggacta atcctccgct
    24181 agccgttgga caatcgtcac aactgacacg tcatacattt ctgcataagg tttcacataa
    24241 acttcccgat ccagcccata actatctggt ttcgttttaa taaccgtacc gatcggcaag
    24301 ttagctggag aattccctcc aagaccggat gtctggacaa catccccttc tttgatatcc
    24361 gtatcaccag ttaattgggt caccactaag gcatggagct tttcatcata gtttttaagc
    24421 aaaccaaacg cttcgccatt agccgaagat acccgtactg gaaaatgatt ggagctttca
    24481 ttagaggatg acagtaattc gattttagac gaagccgtat tgacctcgat cactcggcca
    24541 atcaatcctt tttgcgacat gactgccata tttgcttcga taccgtcttt agaacccttg
    24601 tctacgatca gcatgtcctg ccaactgtca ggcgaacgag taatgacatt tgccgttact
    24661 ttttcgtaac tagtcagcgt ctgattcaac tcaagttctt ttttcaacgc ttcgatttct
    24721 ctctcgtaat tcttgttttg ctgtgaaacg tcatcatagc tatcgatttt ttcttttagc
    24781 cgctcatttt cggcataagt tgaaaaaaga ttatggacag aatctactcc atttcgtacc
    24841 caccgtactg gggcagagat tgttttatca accattgcaa cactgtcatt aacgatggat
    24901 tggaagaaat tgggctttcc ttcattcgct cgctgcgcag cggtcacact tagtatcgtc
    24961 accacgatga taacaataac caaggtaata ataatatttt tattaggatt gaacttcttc
    25021 acaaagacac ctcgaattaa ttagactctt gtgttcaatt ttatcactaa atgccgtgaa
    25081 acaaaaggta agttgctcct cttaagcttt tttttagcaa ataatagatt ctgtcatttt
    25141 tagcctgaaa gacaaatttt tttatttgtt tatggatcaa tctttgcttt gaataactgc
    25201 aatcatacca tctgaaaaag aaaattctgc ggtatctgaa agaaattcgt tacttgcata
    25261 agatgtcgga tattctactt ctttattttc caatacatac ttgctgcctt ctaatgtaag
    25321 attcgagacg ggagtcaagc agcaataagc taaatacttc atatctggta tctgtcttac
    25381 tatatgctct ccaggcaaat aataagacaa ataattttga caatctctga taataagctg
    25441 atgggcaaag ggtttgaagc gaggttccat acctaaccag agattggcta aaagatgatc
    25501 caatcttccg cccgtagctc caatcaaagt gacttccgct tgcgggtaac gttcaaatgt
    25561 ttttaagata cctaactgtg tatctgtatc gtctttttct gcaggggaac gggtatactc
    25621 tttggctttt gcaaatactt ccttctgctc ttcgttcgac aatgaatcaa aatcacccac
    25681 tgccagatct actgggtagc ctgcttgaag caggtacagc gcaccacggt ctatcccgac
    25741 ataggcatcg tatttggaca gcagagactg cggccagttt tgcggattac ctccagcagc
    25801 taataaaatt ttcatttagt ctaatgcctc ttttaatcgt tcgatttgtc cgactggatt
    25861 ttcggctcca tagatatatg atcctgcaac gaagacatcc gcccctgcat ctttacagat
    25921 ttttgctgtt tctggaacga ttccgccatc tacttcgatt gcataagtcc aattgttctc
    25981 tctacgtaga tcagcgagtt ccgtaatttt ttctactgtt tcttcaataa agctttgtcc
    26041 gccgaaccca ggattgacag tcatgactag tacttgatca gccaaaggca aaacatgttt
    26101 gatcatggag actggtgttc ctggattgat aactactcca gctttaactc ctaagctttt
    26161 tgtcatttga agtgcccgat gaatatgagg agttgcttcg acgtggacag taatgatatc
    26221 tgctccagct tttgcaaatg ctggaatgta gttttctgga tcaacgatca tcagatggac
    26281 gtctaacggt aatttagtaa caggacggat tgcctgaaca atatttggcc ctaatgtgat
    26341 atttgggaca aatcggccat ccattacatc tacgtggatg taatctgcgc ctcctttttc
    26401 cactaactca atgtctcttt gtaaattggc aaaatctgca ctcaaaatgg atggtgctat
    26461 cttcattctt gtttcctcct attttcgttt accttctttt tttgcataca ttggttttct
    26521 tttttcgatt tcttgtaaga attgcaaata attgtcgtaa cgtgtctgtg cgataccacc
    26581 tgtttctact ctatgtttta cttcgcagcc aggttcttta gcatgcatgc actctctaaa
    26641 tttgcaatgg acagaagctt ctacaaattc aggaaattgt ctcggcagtt ctcctgcttc
    26701 aattgtcaaa aagtcaatcg agctaaatcc tggtgtatct gctactaacc cgccatagat
    26761 aggaatcagt tccacatgac gtgttgtatg ccgtcctctt ccaagtgcat cagaaatctc
    26821 tcctgttgct aaattcagtt ccggtgatat ttgattcagt agcgtcgatt ttcctgctcc
    26881 agactgaccc ataaagaccg atagccgttc tgggaagtaa cggatcagtt ctgtcgtatc
    26941 acccgtatga ttgggtacaa tcaccggata gcctatttta gtataggttt gcttgatctc
    27001 ttcgattttt tctgggtcgt ctgacaagtc ggtctttgtc aaaaaaataa tcggttcgat
    27061 cgactcgtat tccaaggtaa ctagaaagcg gtcaagtaga ttataagaaa atgcaggctc
    27121 tacgatactt gtgacaatga ttccaagatc aacatttgtg actggtgggc gaactaattg
    27181 attttttctc ggcaagattt ccagaagata gccgtctgtt tgattttcac tctcaaagat
    27241 cacctgatct ccgacaagcg gcgtgatttt ccgattccgg aaatttcctc ttcctcttgt
    27301 ttgataggtc tctccgtttg cgtatacata gtaaaaaccg ctgattgctt ttctgatttg
    27361 tcctttgata agtgccacct ccgtttttgt ttattttacc atacgaagag gaaagtaggt
    27421 gttattccat gcaaacttct caaagtatat ggcttgaaaa ttgatcaaaa gagatagaaa
    27481 cacaaaaaag agaatgcaac aaatcaatgt cgcattccct tctgatatat tttattcagc
    27541 acttattttg aactttctga ggtgctagct gatgaacttg tggagctgga agattcttct
    27601 tttgaagagt tgcttgtgct actggagcta cttgagctgc tagaactgtc tgaagagtct
    27661 ttttcagaac tagaagacgc tggatctggt cctttagagt aaattacgtt cacaaccatt
    27721 cctttggtaa ttgtcgttcc tgcccctggt actgtacgaa tcactttatc tttatccacc
    27781 gtgtttgaat attcggaagt ctcatgcccg atatattctg caccgacact agctaaataa
    27841 ctttgtgctt cgctttttgt atagccggag atatcattca atttaggctc tgttccttgg
    27901 cttacgacaa aattgatgta agtttcttct gctacaactt cacccgaggc tggatcctga
    27961 ctgatgatcg aacctgatgg tacagtgtcg ctatagtcat aagtagcact aatattattg
    28021 atattgaatc cttgtgtaac aagccaatta cgaacagttt cgtagttttc tcctacatga
    28081 ctactcaaag tcactgtttc tggtcctttg ctgactgtga aagtaatcgt gtctgtttta
    28141 ggatcgactt ctgtatcttc tgatggagat tgcgaaatga tcattccgct ttctacctct
    28201 gaactgaatt cctcttcttt ttgaatcaag tcagcagaaa accctaattc tttcaaactt
    28261 gcttcggcat cttcataact tttaccactg taatcatcta atttgatttt tttcgtgccg
    28321 ctactaatat acagagtgac ttcgcgtttt tgcttgactg tcgttcccgc tgccgggtct
    28381 gtcttcacta cattaccttc ttcgattttg tcatctgcaa tttcttctgt ttttgttgct
    28441 acttctaatt tcgcttttgc gagtgtttct ctagcagaag cttcagaaag atcagaaaca
    28501 tcaggaacaa caacttctcc tcgcccgcca gaagcaaaga atacagctgt tccgattcct
    28561 aaaacagcaa gaatagctaa taggatcagc caccattttt tctgtccttt ctttttagga
    28621 tcaggcagaa cttcttcctc ctctggtaag gtttcgtttt ctggcttgtc ttttggcaga
    28681 ggcatagatt tgaatgaatc aggcattggt gcatcttccg taaggggtgt gataactttt
    28741 gtttcattat ccatcacatg aggctgccat ttttcttcgt ttgcacgagc tggtgataat
    28801 actgtagaaa gatcatcaga catttcctcg gctgacttat aacggtctgc aggttcttta
    28861 gccgttgccc gtaaaatcac gttttccagt gcttgtggca catttggatc aagtgctttt
    28921 atagatggaa gatcatcttg aaaatgtttt aaagcaattg ttacagcaga ttcaccatca
    28981 aacggtacgc tacccgtcaa catctcataa aggatgatcc ctaaagcata aatatctgac
    29041 tgcttcgttg ccatacttcc tctggcctgc tcaggggaca gataatgaac agatcctagc
    29101 atcgtattcg tctgcgtgat cgatgtttca gataaagcga tagcaatccc gaaatccgtg
    29161 atttttacaa caccttcatt atcgatcagt acgttttggg gtttcaaatc tcggtggatg
    29221 atttgatggt tatgagctaa agaaatagca gaaaggatct gctgcataat atttactgct
    29281 gtttcataag gaacaggata atgtgtttgg atatatcgtt tcaagtccat tcctttgacg
    29341 tattccatca ccagatactg catgttgtct tcttcaccaa catcgtaaac actaacaatg
    29401 tttggatgaa cgagttctgt tgctgctaaa gcttctctct gaaatcgtcg aatcgcagtc
    29461 tggtcatttt gaaagtcaaa tcgtaagact ttaactgcta catcacgatc caagattaaa
    29521 tcgtgcgcca aaaatacatt tgccatacca ccgctaccga tatttccagt gatttgataa
    29581 cggccattta attttttgcc caactcgatc atacactgtc ctccttatat tcgataagaa
    29641 gaacggtgat attatccgct ccgcctgctt cattggcacg atcaatcagc tcagttactt
    29701 tatgagacaa tgggccttct tgattgatga tcgttcctat ttcttcttca gacagcatgt
    29761 tcgtcaagcc atctgaacat aacagcagtc gatcttttag ttgccaaaga tgagtagaaa
    29821 catctacttc gactgttcca ggcatgccga cagaacgtgt taaaatattt ttccttggat
    29881 ggttcactgc catttcttcg ctgatttctc ctgatttgac tagttcattg actaaagaat
    29941 gatcctccgt caattgcatg attttatctt cacgaatcaa ataagctctg ctatccccaa
    30001 cattggcaat cgtgaaccag tcatctgaca gagcggccgc tacgattgtt gttcccatac
    30061 cgttatattc cggctgttct tgtccacgct gataaatcag catattttct tcttgaatcg
    30121 attgaatgaa ccattgggcg attttttcat cgtcaacagc ttcttgtttt tcccaagctt
    30181 cgcctagatt cgttaccgcc atctgactgg caatgtctcc ggcacgatga ccacccatcc
    30241 cgtctgctaa tacagcaagc ttgagacctg aacggctggt aaatacactg gcatagtctt
    30301 gatttgtgtt acgtcgtctt cctacatctg attgatattc aatctgcatt ttttcacctc
    30361 attacttttt gcgcaaacaa caaatgaaaa atccatctgt gtaaaactga tgcggataca
    30421 aagtcaacat tttctcttcg attgatgatt gtagcatagg attggtcaaa acatcaatcc
    30481 tctcaaaatc agggtgtctt tccaagaaag cagaaacaac gtcttggttt tcttctttta
    30541 agatcgtaca agtgctataa gtcagaatac cggaagactt taaagttggt gcgcagcttt
    30601 ctaaaatttc caattggatt tttggtaaat tcgctaattc atccggctgt tttttataac
    30661 gaatatctgg ttttcgccga agcagcccaa gacctgaaca aggcgcgtct actaaaatcc
    30721 gatcaaactg ctctgcttcg aactgtttac tgacttctct agcatccatc ttttgagcgt
    30781 agacagcaga agagacacct agacgtgctg cattatcttc aatgagtttg actttgtgtt
    30841 cgtgtacatc taaagcgacc acttctccac cgcatgacgg atctaaaaaa gaagcaatat
    30901 gcgtcgtctt acctccgggt gctgcacagg catctaagac atgatgttca ggctcgattt
    30961 gcatagacgg cgctacaagc atcgaacttt catcttggat cgtcatgacg ccatcgtgga
    31021 acaatgagct agaagctaaa tgcccttttt tcgctactat accgtatgga ctgacttggc
    31081 ttttttcagc tgtgatctct tcttcttgca aaacagtgat ggcctgatct ctggaaagtc
    31141 ggcgtgtatc tactcgggca ctagcatggc taggctgata tagcgataaa ccgagctttt
    31201 cagtttcttc gtatccgatt tgatccacca gtcgtttcgt catccataga ggcaggctga
    31261 ttttgacaga aagtctttcg ataggatcag caatgccttg cagatctggt gctccttgac
    31321 gctgataatt cctcaagaca ccatttacaa atttccctgt cccaggattt ccttttactt
    31381 ttgcgatttc gaccgcctcg tttaaaatag catgtgcagg gactttatct aaaaattcta
    31441 attggtatac agaaagataa agaagcatct tgacccagtc atccactttt tttgctttag
    31501 cgatcaatgg tgcaacgtaa aattccaata gtcgctgatg gctaatcgta ccatagatca
    31561 attctgtaaa taaacccaca tctttttgat ttagctcgct ttgtttgatc atctcattca
    31621 acaaaagatt cgagtaggcg ccacccttgt tcactcgctc taatgtcagt aatgccatat
    31681 atcgtactga ttttttcatt tttttaggga tttttttcat tatttcacct gctgaccaat
    31741 ctgaacttgc tgaccgcttc cgttaaggaa atcatgtacg gcctgttttc ctttaccagc
    31801 tggctgtaat tcattgatgg ctaagacggt ctgtttaccg caagcaatcc atagtttttt
    31861 tttgtctttc cggatgatcg taccaggtgc tttgtctgta gtttctgcca atacttcaac
    31921 cgataataat ttccagcgta tgccctcata ggtcgtgaat gcaattggcc aaggacgcat
    31981 tccgcgtact tggttgtcaa tttcttctgc agttttatgc caatcgattg cttcttgttc
    32041 ccgtgtgatg tttggcgaaa aagttgcttc tgactcgtct tgaggtactg gtttttgtcc
    32101 atccaaaata ttgggcaatg tttctagcaa tagctttctt cctaaaaggc taagcttttc
    32161 aaacatcgtc cctacatcat cttgtttagt gattggtatg ctttcttgcg catagattcc
    32221 gcctgcatcc atttttttga tcatttccat gatcgttaca ccagtttctt tctccccatt
    32281 catgatggca taatgaacag gcgcacctcc ccgatattta ggaagtaaag aagcatggac
    32341 attgattgcc cctaattttg gtacttgcaa taacttttca ggcaagaatt ggccaaatgc
    32401 cgcagtgacg atcacatcag gcaccaattc aatgatttct tccatttctg gcgaaccgga
    32461 gattttctct ggctgcagca cacggatacc gtgcttcaga gccgcttttt ttaccggtgt
    32521 cggcgtaatt actcgtttcc gcccaactgg acggtcgggc tgtgttacca ctgcctggat
    32581 ctcgtaacct gattctatca gcccttcaag aatcggcaca gaaaaagcag gtgtgcccat
    32641 aaatactagc ttagtcatca agatgttcct ccatatattc ttcaagttct tcttccggga
    32701 tctgctgtat cattttctca atgaacaaga taccgtctaa gtgatcgatt tcatgctgga
    32761 aggcacgggc taaatagcca aaagccgtca cttctatctc ttctccgtct cgatcataat
    32821 aacgcacggt cacttcatct gctcgcttga ccgttccata gacatgcgga atactgagac
    32881 aaccttctac gtcaaggctt tcaccttttg cttcgatgat ttctgggtta atcagttcaa
    32941 atttctcgcc ttcatctact tcgatcacag caattctctt gttttgtcct acttgaggag
    33001 cagcgatccc tattccgtca ttcgcaatca ttgtctcata taaattgtct aataaagcga
    33061 ttgtctcgtc cgtgattaca tcgattggct gagcagttct ttttaattta tcattagggt
    33121 ggatcaatat aggatagcgc ataatttggc cctttcttaa ataaagttta atggttcgtt
    33181 gtcaattgcc acaaaaagac cttgtcgctg ttctttctgg cttccattca aaatttcatc
    33241 caaaacatga ggaagattcg gttcatgttt atatttgatg attagttgat aataatatcg
    33301 gtttttcact ctcaaaatca tgctgggcgt tggccctaat agcaagcttt gagggcttaa
    33361 cacttctttt agctgattgg caatctgaaa gattttcttt gccgctactt gttcttcagg
    33421 atggctggcg gttattttca cagtaaagta ataaggagga tagcctccac gatgccgtac
    33481 atgcatttcc tgctgataaa actgctcata attttgtttt ttagccaatt ctatggcgta
    33541 atgttgagga ttgaatgttt ggatcacgac ttcgcctgct ttttccgctc gccctgctcg
    33601 tcctgaaact tgggtaagca attggaatgt atgctcacta gaacgaaaat ccggtaaatt
    33661 cagggaggta tcagcattca acaccccaac taatgtcact tctggaaagt ccaaaccttt
    33721 agcaatcatt tgtgtcccta ataatatatc tgcttctttt gcaccgaatt tttgtaaaat
    33781 ctgttcgtgt gccccttttc ttcgagtggt atctacatcc atacgcaaaa tcctagcttg
    33841 cggataaagt tctcggagtt cctcttctac tttttgagta cctgttccat agtagcggat
    33901 tttattgccg ccacaattag gacagcgatt gggaataggt tcttcatgtc cgcaataatg
    33961 gcagcgcatt gaacgtgtat ccatatgcag tgtaagagag atatcgcaat taggacatgg
    34021 aagaacaaat ccacagtccc tacacatcac aaaagacgaa tatcctcgac gattgagcag
    34081 taggacagtt tgttcttttt tgtctaatcg attttgtatt ttttcctgca aattagcaga
    34141 aaaagtagag gtccgatgat tctgaaactc ttcacgcata tctacgatct caatagctgg
    34201 aagctgtgca gctgctttgg ctcggtggtt taactgcaat aactgataaa cgcctttttg
    34261 agctcgtgct cttgattcta aagagggcgt cgcgcttcct agaactattg ggcaatgatg
    34321 atatttactg cgccaaattg ctagatctct cgcatgataa cgcggtgtct catcttgttt
    34381 gtaacttgat tcatgttctt catcgataat gatcagcccg atatttttca gcggggcaaa
    34441 aatagcagat cgtgcgccta ctactacttg cgcttcttcc cgctcaatct tgcgccattc
    34501 atcatatttt tcaccttggg aaagtccgct atgtaagacc gcaactgatt ctccgaagcg
    34561 tcctttgaat cgctcgacca tttgcggagt caatgcgatt tcaggcacta acataatagc
    34621 cgttttattt tctgacaaaa catcagcgat tgcctgaaga tatacttctg ttttcccgct
    34681 gccagtgatt ccctccagca aaaagacctg atctttttgc tgctgacctg ctgtgatgat
    34741 ttgttcgaca gcattttttt gttctgcatt cagttccaat gccgtcgttt ggtcaaatac
    34801 tcggtcttta taagggtcgc gataacgttc tgattctata aactccagcc agcccttttc
    34861 ttttccttga ttcaagacag cagtactgat tcctttattt ttgaaataag caattggttc
    34921 ttcttggctc agttcagata aacacaaaag aagttctttt tgtttcttgg cattttgccg
    34981 taattttgcc cattcttctt cgatttgctt ttcagttaac aaagaacgga ccaaacgaat
    35041 cgtttttact ttatttcgtg tatggacttc atatttgata tctactaatt gctcttggcg
    35101 ccagcgaatc aattgagaaa ggctgccttc ttcttctgct tccttccagg aaatcacttc
    35161 tcgctgatca aacaatacct gaacttctgg tgtgtctgcc aaaggataga tcaatttatc
    35221 atattctgct ttcatcacac tcggaagcat cgtttgtaga caagtgattt tgaatgcgta
    35281 agtaattttt ttcatataat cagctaatga aagtaattct tcattgacca ccggagcaag
    35341 gtctagcaaa cgaataactg ccttcaaaga tggattagct gattcttctg atttttggat
    35401 agccataaca aatccttgga catgacgatt gccattacca aaagggactt ctactcgcat
    35461 cccgacttgc aaagctgttt ccatttcaga gggaaccaaa taagtgaatg gctgatcggt
    35521 ctgcatagta ggtacgtcca caatgacttc agctgttaat gtcatggttc gtttcctcct
    35581 ttttttgtct tttcttatca agcgacaaaa agttccttgc ctattttact agagatcgat
    35641 ggatttgtct tatcttctgc caaatcctaa caaaaaatta acagcagata agaaaaaaaa
    35701 gaactgtgtc aaaaagttca gacacagcct tttctaccag acaataagtg gcgaatgttt
    35761 gaaaaggaaa cagctgggtt tgcttttctt tttagatgtt cgctctattt ttctttatta
    35821 cattttttgc tcttcacgga tacgtgattc caattcgtgt tgttcacgct ctttttgtgc
    35881 ttgacgttcc tcttcttcca tcttcaaacg ttcacgtttt aattcaggat gtggatcatt
    35941 gactacattt cctgcatcga tttcttctaa agcttgaccg acgcttttta ctgaatcaaa
    36001 agaatctaga gtaggctgtg cacttgcatc caattcatgc gcgcgtttac ttgctaaaat
    36061 cactagagaa tattttgaat ttacacgatc taatagtgag tcaattgaag gttttaacat
    36121 cataagacta catctccttt aacattttaa tatatttacc gattacgcga tctactcgaa
    36181 aatgttcact ggcaataatg tttttgattc gttcaactgc tagcggcact tcatcattta
    36241 caacagcata gtcgtaaaga gccatcattt cgatttcttc ttttgcaact ttcattcgtt
    36301 tttcgattac ttcatctgca tctgttcctc ggcctacgat ccgtgatttt aattccgcta
    36361 aatctggcgg agtcaaaaag atgaatacac catcgggcac tttttctttg acttgttttg
    36421 ctccttggac ttcaatctcc aagaaaacat cttttccttc atccaatgtc ttgttgacat
    36481 atgacaaagg agttccataa taattcccga catattctgc gtattccagc atctctccag
    36541 cttcgatcat tgattcaaac tcttctttgc ttcggaagaa ataatcaacg ccttcgacct
    36601 ccccttcacg cattttacgg gtagtcattg agatcgaata ctgaaaatca ttatcctcac
    36661 tctcaaaaat tgcttttcgt actgtgcctt ttcctacacc ggatggacca gacaacacga
    36721 ttaataatcc acgctctgac atgacgacgt cctttcaact agtctttttg tacttatcgt
    36781 ttattttgca ctttttttct gcaactttca aggttatctt taattatagc tagaaattgg
    36841 taaaaaagct accctgtacc aagaggtcgt aaaaaagctg tcctgcatca agtaataaga
    36901 acagccaaac ataaacagct tctcatgttt ttcgtttggt tggggttatt atcgcagatg
    36961 caagcttttg aacgccgtgt ataagaggtc gtgaagaagc cgattagttt cgagtatgaa
    37021 gaaaaatttt gtgaaaatag tttctcacat ttttgcataa atttggctta ataccgagaa
    37081 aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga attttgtcac
    37141 aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat tctgtttatt
    37201 tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa gtattcacta
    37261 cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct acctcttctg
    37321 tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg ttgatcaaaa
    37381 taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca aagccgtttt
    37441 tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg aacgttacgt
    37501 cataatattt cattatctct acctctttcg tcattcaata ttttgtactt gttctctgat
    37561 tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg catttgattt
    37621 ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta attcccgacc
    37681 tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg ccagacgatc
    37741 cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca acaaccgttg
    37801 ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta tttgaaattc
    37861 cttttcatag atttctacaa aactatcgag tttttttagt acttctttga attcttcagt
    37921 attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg cctcaataga
    37981 atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca tgctctcttc
    38041 cggtttttct tctaccgtta cgaagttttc gtccagcacg aagcgttccg ccatccgact
    38101 aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca attgagtgat
    38161 aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc caatataagc
    38221 tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa gctgacgaaa
    38281 atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta gaaaacgctg
    38341 gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga tggctttgcc
    38401 aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt tctattgctt
    38461 tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt ttttcatggt
    38521 ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg actaggttca
    38581 gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct acgatttcat
    38641 atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata ggatcagtaa
    38701 tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt ttccttgtag
    38761 cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct ggtattttcg
    38821 ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat catccggcat
    38881 actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat agatttcatt
    38941 gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc atgtctctgg
    39001 tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc ttttgaaaaa
    39061 agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc agtatgttct
    39121 tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta atcgtttttt
    39181 catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa aaagcagaaa
    39241 gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg gcatacgaat
    39301 ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg ctcctttgtt
    39361 aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt tattttttcc
    39421 gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc aatctggtat
    39481 ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg gcagtttagt
    39541 agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat ccaaattgtc
    39601 tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg ctgttttcgt
    39661 catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag ccatttctgg
    39721 taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt ttttcatatc
    39781 tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga taatctcaaa
    39841 gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac cgtgcgctcc
    39901 tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt gtgtggttcc
    39961 ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag attgaaataa
    40021 aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc gaaaaaattt
    40081 tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat ctcctctact
    40141 tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag cacattgctt
    40201 ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa atggaagggg
    40261 ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt aaactttttt
    40321 tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa aaggtcatga
    40381 gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct cctttaaata
    40441 aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat gaaaacgtga
    40501 ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat gttgtaaaat
    40561 aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt tatgtacata
    40621 ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac tttgcaaaca
    40681 gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct gctggagaat
    40741 atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag cgtttctttt
    40801 cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt actgatttaa
    40861 cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt ggtcatatga
    40921 aaacacatct tcattcgccg tttttttata aactacagaa taattttgta tacttcgatc
    40981 ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat aggatttttg
    41041 ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct tttttcaaaa
    41101 aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt aatttgatgc
    41161 aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa tatcgtatcc
    41221 caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat cgagaagagg
    41281 aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg gtagaagatg
    41341 ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat aaaaaggaaa
    41401 caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt tacagctcct
    41461 gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat aaaacgatga
    41521 tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa aagagccaag
    41581 gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata aaatgccaaa
    41641 aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta atttgtttcg
    41701 tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct gcgcctgcaa
    41761 aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa taaacttgtc
    41821 ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc tttgtccctc
    41881 ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa ctgctgccga
    41941 tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt ccttctaccc
    42001 aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc acaaaggagg
    42061 aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc tcgcataacc
    42121 gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga ctcccctttg
    42181 tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt tgttttcatg
    42241 gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga ttttgtcgat
    42301 tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga tagctgaatc
    42361 ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag catacacact
    42421 agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg ctgtatcgat
    42481 catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat tcattacttc
    42541 tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt tcaaaaattc
    42601 cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga caacatcatc
    42661 gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca tcaaatgatc
    42721 gactggaata tcaaagaaac cttggatttg gactgcatga aggtccaaag tcagcattct
    42781 tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg gttcccgtgc
    42841 acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt tgattgtttt
    42901 tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt tatcattgac
    42961 tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt cttcaatgtt
    43021 tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact cgacgccgac
    43081 tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa tttttaatct
    43141 tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa ctctagaatt
    43201 ctacctaata aatagtagtc atatttttta aataaatcaa gtgattttgc aaaagtctta
    43261 gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg ctctcgcaat
    43321 tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa tcgaactgtt
    43381 tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc tgtggtcgcc
    43441 gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac cacatccgac
    43501 attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga ctttagttcc
    43561 tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt tttcgccaat
    43621 ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct tgacatggct
    43681 gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt ctacgatttt
    43741 tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga tttgtacacc
    43801 tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg tcgttgctga
    43861 atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc tcatgatctc
    43921 atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa aatcatccgt
    43981 ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat ctgttagata
    44041 gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca aagcttcgtt
    44101 gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg gtgttgcatc
    44161 tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc gtccatatcc
    44221 tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc cttggtgata
    44281 ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac tgataactaa
    44341 cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat gtcctgttcc
    44401 caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt taacttgttc
    44461 tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga cccgattaat
    44521 gatatgttct accataggtt taccagaaac gggatgtaaa actttatata attttgactt
    44581 catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca actgcgtcac
    44641 tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt caacaaaaca
    44701 agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc ataacgggcc
    44761 tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca cactactcat
    44821 aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa acggtaggct
    44881 tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc tcaataaacg
    44941 gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca ggacgctgat
    45001 ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa gccaaattta
    45061 tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcggct
    45121 ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata tttttcgttt
    45181 gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg cgatgaccgt
    45241 tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat tcttcaatca
    45301 agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact acaaggacac
    45361 gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt tcagaagatc
    45421 cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc cggcgtacaa
    45481 taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg ccttttgtgg
    45541 ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg attcttccaa
    45601 cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat cctcctggaa
    45661 gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt ttcgcctctt
    45721 catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt gtttccaagg
    45781 ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca ctgatagaag
    45841 atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca tgcgggtgat
    45901 tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc acctattcca
    45961 actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa aaattcgagc
    46021 attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga agcctataaa
    46081 aaatttttcg tttttataag gcttcttttc tttataattt agttattttt tcttctgaag
    46141 gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa gactaatgtg
    46201 attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga cagcatccct
    46261 agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc taatcgcata
    46321 ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc aatcgggatc
    46381 atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa atgaacgggt
    46441 agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg ccgtttgaat
    46501 aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac ttgctcccat
    46561 gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga attccctccg
    46621 ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat ggcaatggag
    46681 atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc tgctaataca
    46741 acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa cgctacccct
    46801 gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat cactaaaaac
    46861 acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc tcttctcatg
    46921 aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg atctgtctgt
    46981 ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat ttcccatgga
    47041 catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca tccatacctg
    47101 ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc gctaaactga
    47161 ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata tcccacatcc
    47221 ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga cgcttgaacc
    47281 agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta ggaaaacctg
    47341 cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt ccttcttgat
    47401 ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac gatgctttca
    47461 ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca cccgcatcta
    47521 catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc aaatcagata
    47581 tttcgatata acgcacctta caacctccat tctaaaactt aattgatact ttcttttaaa
    47641 gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat ttgttcatta
    47701 gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt cgacaatgtc
    47761 tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt gtttttcttc
    47821 acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg tgaaacgccc
    47881 gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc agcatgctga
    47941 gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg atccagtgct
    48001 tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt atctggatat
    48061 ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac cggatcgagc
    48121 caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc ttcatgttcg
    48181 tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat caaggtctgt
    48241 ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga actattatac
    48301 acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc gaaatcatgc
    48361 ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac gatctctttt
    48421 gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt tttgtctgct
    48481 tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac cgtagctgtc
    48541 aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt ttacgattta
    48601 ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc atcaatttct
    48661 gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg ctcatatcta
    48721 gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca gtttttcatc
    48781 acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt cctcacaaaa
    48841 accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca aggcaaaaac
    48901 ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca tacgctcttt
    48961 gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt ttcccatttt
    49021 tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt ggatgtcttg
    49081 atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga cactcattct
    49141 tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga tttcttcccc
    49201 tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg taccgacttc
    49261 caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt ggttgatccc
    49321 tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta ctggaatatt
    49381 cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta gcaataaagc
    49441 agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg tttctacaat
    49501 gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta cgctcgacat
    49561 caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca gtcctaaatt
    49621 tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa aagtctaagt
    49681 cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct agtggttgat
    49741 tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa caagttctag
    49801 tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc ctttttcttt
    49861 tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt tcctataagc
    49921 aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag cagactggaa
    49981 ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt gaaagaaaga
    50041 aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt ccgagtagcc
    50101 cattttctcg tatacaataa acagattggc taacagatag tcagctaatt cctcagattc
    50161 tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg gctgagcggt
    50221 gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag ataatacata
    50281 tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa gccatttttg
    50341 tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc aagtaaaatg
    50401 gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag acaagtcttc
    50461 tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac ccaattcatg
    50521 aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc ctaaacaatc
    50581 tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc caactggatc
    50641 tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt gatcttggtc
    50701 gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc ttgtagctgt
    50761 gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac tgccaagctt
    50821 cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg agatgcccaa
    50881 accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat gatttcctgt
    50941 tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa cgataaacaa
    51001 aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga attttgttcg
    51061 ataaaattct tttctggata accacacagc taacagaatc aagacatata ccaatatcaa
    51121 ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta aagcaatcgt
    51181 aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga gtaataaaaa
    51241 gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca ataatacttg
    51301 aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca tcatgatccc
    51361 cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa acagtcgcgg
    51421 aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca atagaagtcc
    51481 cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa ctactgctac
    51541 atcttgccga acagacaatt gactcattcc taagatcatc aaaacgtcaa aagtccccat
    51601 tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca taggatagat
    51661 cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata ccgcaagggc
    51721 tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg gataaaactc
    51781 gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg ctaaaaaact
    51841 accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa taaaaaagac
    51901 atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata gtgcgacttt
    51961 tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac tagcccgcag
    52021 acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg ttacccacgc
    52081 agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta agactctgat
    52141 cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca gaatcatgag
    52201 caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc aactcatgcc
    52261 attagcaata tttgcgactt gatttgccac aaagactaac acggagccga aaaaaatcag
    52321 ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt tatttttcac
    52381 attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc ttatttattt
    52441 taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa agatatccta
    52501 atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat atggcacaag
    52561 ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg ttcgtttcca
    52621 gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat gcatgcaaaa
    52681 gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa ccaaaaatca
    52741 ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc atttctattg
    52801 cttcaggaaa atcattaata gatttagaaa cagcgcttga agatcctcag gcctccatcg
    52861 tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg atttgcaaaa
    52921 atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa gcaatcggca
    52981 gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct ggcagctcac
    53041 ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg aatggtttgt
    53101 ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt caaaaattcc
    53161 tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct ggcggtacaa
    53221 ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc atcaaaggaa
    53281 tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga tagcaatgtt
    53341 ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt cttttgtatt
    53401 ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac tttgatgtgt
    53461 ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa acgaacagcg
    53521 tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc agcttgaact
    53581 gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact tcttaaacga
    53641 cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga gagcgcatct
    53701 gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg atgagaagcg
    53761 atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc accgatctca
    53821 acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag caacccggca
    53881 cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc taattttgca
    53941 acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg cagacgtccg
    54001 atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc tgcctcttcc
    54061 ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat ttcttcgata
    54121 cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg tgcgatttct
    54181 cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc gatgattaaa
    54241 tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc aatgatacga
    54301 cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga aacttgatct
    54361 gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc tgcttcttct
    54421 ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag ctcttcttca
    54481 gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat tttttctagt
    54541 tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc aattaattgc
    54601 tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt ttctaacgag
    54661 tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg agattttaat
    54721 tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg attttcttcc
    54781 ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc actatcgatg
    54841 attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga ctttgcgacc
    54901 ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat gttgaatacc
    54961 ataaaatcca cctccatact atctttttca tttttatcat ctatacagct tctatgataa
    55021 attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa catgcacaac
    55081 tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa acggctttct
    55141 acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat aggtaaacct
    55201 ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata tttttatttt
    55261 atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa aaaacggcag
    55321 gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat ttttattctt
    55381 ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact tcttcaccaa
    55441 taccataagc tgctctaact agagcagaaa cttctgccat catttcagga tgattagcca
    55501 tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa gaataccaag
    55561 caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct ccttcttgtg
    55621 agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt gctactttgt
    55681 tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt ttcaattgtt
    55741 ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt cctccaggag
    55801 tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg atgaaaatag
    55861 cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga gacatcaaac
    55921 gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct cgtggaacta
    55981 aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact aaagcatcag
    56041 cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca tcgatattca
    56101 cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg aaagcggccg
    56161 ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt ttacctgaac
    56221 tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca cctaaagcga
    56281 catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt ttttcgccca
    56341 atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca gcatctaagg
    56401 ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat cagagcaaca
    56461 tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac cgaacaaata
    56521 ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct tgcataaccg
    56581 cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa accacgccgt
    56641 ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac gtgtccggtc
    56701 cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt gcttgaatgg
    56761 ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc tccggatcaa
    56821 tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct ggaaatactt
    56881 cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc aaactttccg
    56941 ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt gctagcgaat
    57001 tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt tcttctaatg
    57061 ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt cgtaatgtca
    57121 cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca atcagatctt
    57181 ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact ttagaaatta
    57241 gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc acaaacattg
    57301 gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct gtttgataaa
    57361 aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg ataatctggg
    57421 actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat gccaataatt
    57481 ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca gttgcttctt
    57541 ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt tcacttcttg
    57601 tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca actgtttgat
    57661 aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca ttcgtattca
    57721 cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc attacttccc
    57781 gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag agggcaagga
    57841 gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc tcctgccaaa
    57901 acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg aaattatccc
    57961 ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata cttacattga
    58021 tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga tagtaaagat
    58081 cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga atgggatatt
    58141 attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt ttcccggcca
    58201 agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg tgacggctaa
    58261 ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt caaccaacat
    58321 gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact tgccaaaatt
    58381 agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga tactagctaa
    58441 agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc ctacgttaaa
    58501 ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca tacaaattct
    58561 aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc ctattctacg
    58621 tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt tattcaaagg
    58681 agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga cacagatttg
    58741 tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat ttatacgatc
    58801 attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt tcccctggat
    58861 taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca ccaatcgtga
    58921 tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt gctgccagtg
    58981 tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga ttgacagcag
    59041 taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg gcactgccag
    59101 aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt gttgattcta
    59161 ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc tcgactgatc
    59221 cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga cgatcttgcc
    59281 aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat aaaatgacag
    59341 gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct tttctagaag
    59401 tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg cttttcccat
    59461 caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat tgccgaataa
    59521 atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg attgcttcca
    59581 aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt tttttattca
    59641 ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca tcttctccag
    59701 tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt tgggtgctgt
    59761 gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct gccaactcct
    59821 cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact tgttccttgt
    59881 gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca atcagctgtt
    59941 cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt atgtttctct
    60001 aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt caaaagcttg
    60061 catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt tacttggctg
    60121 ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg tgttccagaa
    60181 gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat tttcgtaaat
    60241 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta cttcgtttga
    60301 ttttatttta atataagttg attaaaagag agcatgattt gttttatttt ctcactaatt
    60361 tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc tactacaagt
    60421 ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt ctcatgtaaa
    60481 actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg tctttcattt
    60541 ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat aaactttgcg
    60601 taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt ccaagcattt
    60661 tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg aatccaagaa
    60721 tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg ctgaagtccg
    60781 caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg ataattcctt
    60841 gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg aacaacagat
    60901 tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg tctaatcctt
    60961 taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt tgtttgatga
    61021 tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg aaattttttg
    61081 cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta ccaactacaa
    61141 ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag tcttgagctg
    61201 tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg tgtgtaggat
    61261 acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca tacatttgga
    61321 tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag taaggtgctt
    61381 gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta gaaaacagat
    61441 agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc ccaaataatt
    61501 gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg gcaattccat
    61561 ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg atcgaaccat
    61621 aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac aaatacacgg
    61681 tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca tattctgttt
    61741 tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat ttgctcagct
    61801 acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc ttcatcagat
    61861 aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc ttgcggagag
    61921 tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag ttccaactct
    61981 gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag tacttgattt
    62041 cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt atccacgcta
    62101 ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag tttagagtga
    62161 ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg ttcatcgtaa
    62221 tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc acgtacttgt
    62281 cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata aactgtttcc
    62341 cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc aacatcgccg
    62401 acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga cgctagcgaa
    62461 ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt ttgttccggg
    62521 ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt atcttccttc
    62581 aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa ctgatcaaac
    62641 tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac cgcttgagaa
    62701 aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc gtttagccaa
    62761 tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag ctctgcaagt
    62821 tgcgcactta actttgtctg atccgaataa ttcaaactat ttgtttccaa catgctgctg
    62881 agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg gataaaaatc
    62941 cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc tgccaattga
    63001 tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt ttaatgggtc
    63061 aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca attcgccgtt
    63121 ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca aaagaaacag
    63181 acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta aagacaaata
    63241 aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc gtggagatgt
    63301 cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg taaaccaagt
    63361 ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca caggtacttc
    63421 tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg tcacatttgc
    63481 gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg tcttattctt
    63541 agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc aagtggaagt
    63601 ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc ttgccaaaca
    63661 agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata cttctaaata
    63721 ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct
    63781 taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca
    63841 tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg
    63901 atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc
    63961 tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata
    64021 ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa
    64081 aacgtatgcc aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc
    64141 acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct
    64201 tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca
    64261 taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt
    64321 aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt
    64381 aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat
    64441 aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca
    64501 acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg
    64561 gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt caagtttacc
    64621 ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt tttctaaatt
    64681 attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc ccgtaagcgc
    64741 tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa tcaacgcctt
    64801 gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg caattttcga
    64861 ttgcttcttt taataaaaga tgctgaattg ctaaaggttc ttgcaatgtg atctctgcta
    64921 aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct ttttgatcac
    64981 gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt ataacgcttt
    65041 tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat gcctgatata
    65101 aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa taataggtgt
    65161 ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat gcttcttcgt
    65221 caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc cataaattcg
    65281 tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat atgttattta
    65341 ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc ttcattccat
    65401 ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc tattgttttt
    65461 tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc tccttgggaa
    65521 aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt caaacggtca
    65581 ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc tttcgtaaaa
    65641 acaacatcca actggtattt cttataattt tgttggatgc ccggaactag ttgggcatcg
    65701 aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg atgtaaaaga
    65761 gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc cggccacgaa
    65821 ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta ctccccctga
    65881 cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt taagctctgg
    65941 acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa tcctggactc
    66001 attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt ccatttttgg
    66061 aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt gagctgttgc
    66121 acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc cccagtggaa
    66181 gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat cacaccatcg
    66241 acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc ttcgatgcta
    66301 tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat cagttggtca
    66361 agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac gccgtgatcg
    66421 ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg ttcacgtgcg
    66481 atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa gagtttattc
    66541 cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa attatcttct
    66601 aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt tttatttgaa
    66661 tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt tgttctttct
    66721 ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt ccatccgctc
    66781 ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg cgacccgata
    66841 cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc ctctgcgata
    66901 ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa tcaaaaaggc
    66961 ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg gttttgtttc
    67021 tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc caacataagc
    67081 caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca tcgggttcct
    67141 tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat ttcgtcgctt
    67201 cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg ttcaatctct
    67261 tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca ttgcgagaat
    67321 aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag ataagtgttc
    67381 agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa atcatcgtcc
    67441 atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc cgcatcatct
    67501 gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt attcttcagt
    67561 cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat cggacgacgg
    67621 tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt gatcatttca
    67681 tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc gccaatcgtt
    67741 acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc ttcactttgt
    67801 gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg gatatcgatc
    67861 gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc gggacgtcct
    67921 ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca taaagcgaaa
    67981 tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc tccgacttcc
    68041 agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg ggtacggtaa
    68101 tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg aataaatgct
    68161 aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggttc gacattcaac
    68221 gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg tgctgtaata
    68281 cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt cgatacgaaa
    68341 tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc aatggtgcta
    68401 cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata cataccgaca
    68461 tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt gtagattttt
    68521 atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct ggtactccta
    68581 ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg attttggcgt
    68641 tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg gctccttgtt
    68701 taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt acgccatgga
    68761 ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc attccatggt
    68821 cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca gttaggaaac
    68881 gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat aaaaaatgag
    68941 agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc tcagctgtcg
    69001 aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac caactcatga
    69061 ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa agaaaagaag
    69121 cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca cttttcttca
    69181 taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta ctttgtttcc
    69241 tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga ggcatttcgg
    69301 caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc agctgcttac
    69361 ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat gatttttcac
    69421 gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct gatacagcta
    69481 cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga acagctttga
    69541 tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt gctttgaatg
    69601 cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct tcattcaata
    69661 caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca tagctcattt
    69721 gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca tctgggtttt
    69781 ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat gcatctagat
    69841 ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg aaagctgcgg
    69901 gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt tcgaagattt
    69961 cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt gcatctggta
    70021 gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca cgtttgctta
    70081 gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt ggtggtgtcc
    70141 agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg tcatctccac
    70201 gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa ttataagttg
    70261 gcataccatc gcgtttttgg atgacaaagt cgccaccgat attatcggat tcgaacgaaa
    70321 tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca cggaaacgta
    70381 caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc aagttcgcac
    70441 atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt tctgcttcta
    70501 attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc tgatcaatca
    70561 gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct ccaggatttt
    70621 caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg cttttttcgc
    70681 catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag tctccatcat
    70741 tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata tgcaggtgcc
    70801 cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc ttctttcaaa
    70861 ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata tcatttattt
    70921 aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca actggttgaa
    70981 tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt tttctctgtc
    71041 tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat catgcgtcca
    71101 gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat gtaatgctgt
    71161 ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg ttggcgttct
    71221 gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac tggttttacg
    71281 gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga gactttattc
    71341 aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt gatcaatttg
    71401 ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga tataccctct
    71461 tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg tttcaaacta
    71521 tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat catcaaggtt
    71581 ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat cacgcttgta
    71641 tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag ttgactctca
    71701 acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac tttcttccat
    71761 tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat catcagtaaa
    71821 atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt cgagatcaca
    71881 acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata agtcaagctg
    71941 acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt ggccaacagc
    72001 aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt attattcagc
    72061 catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga aatacccaag
    72121 cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt ttttcctccg
    72181 tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc caaagttgct
    72241 actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt tttaggtagg
    72301 tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat atgactgaca
    72361 cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg ctgtgttcct
    72421 ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc tggttcattt
    72481 aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag caacccagct
    72541 cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc tgttgttgtt
    72601 cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac caaaattgga
    72661 cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag gcgttcttct
    72721 aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat ttcaaaaatc
    72781 ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg aaaactatga
    72841 tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat tcttgggccg
    72901 gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc atttgtttta
    72961 gcggttttga gtagttctgc agtggtttct cttacttggc tgacacttcc tgccacactt
    73021 gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc aggggagata
    73081 tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata aaattctgtg
    73141 ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc ttcgccggat
    73201 acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa cagcaaagtg
    73261 gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac cacacctccg
    73321 cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt tttagggacg
    73381 acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg agttctgcgg
    73441 tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca atttgggcag
    73501 cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg tacttttgat
    73561 ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat caagcttaag
    73621 tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga gcagtcgttt
    73681 gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc tcgccttttt
    73741 tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg ccttcatttg
    73801 cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac actaaaaacc
    73861 gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct cccatgtaag
    73921 ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct gatacatctt
    73981 ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc cagatacttg
    74041 gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt gtagcgcgct
    74101 gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct ctttttctca
    74161 ccggttttcc tccctaaata aactactcct attctaacat atccgaggct gtaaaagact
    74221 ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa ttcgttcttt
    74281 ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa
    74341 caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac atgcgtaaag
    74401 aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg atttatccca
    74461 atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct gatcttagaa
    74521 atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt atgcataaat
    74581 tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg gctgttggtc
    74641 aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa cagacggcac
    74701 agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata
    74761 cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac gatactgtag
    74821 cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg tcagccatca
    74881 tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac gggttttatt
    74941 cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat aaaatcgatg
    75001 aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga
    75061 gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt ttagcaaatg
    75121 gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt actttattta
    75181 aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag atagcgcgca
    75241 acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac
    75301 catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag aaaaagcagt
    75361 cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa
    75421 tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg gaaaagtaga
    75481 tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc cactaggcgt
    75541 gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt
    75601 caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt
    75661 attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt atgccatcca
    75721 gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga cagaatactt
    75781 agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag aacaggcaac
    75841 ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata aagaagcaca
    75901 gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa
    75961 cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc cagctattga
    76021 aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt tagaatatct
    76081 agagacggct gctttagcag aagacacaga ttgggatact gaatatctag attatatcct
    76141 tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc ggcataatac
    76201 taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt tcttaaatga
    76261 agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg gatcggtatt
    76321 tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg gtccaatggg
    76381 gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa tccgcgaata
    76441 atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa
    76501 ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc ttatttctct
    76561 gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat tcaaaaaacg
    76621 aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg
    76681 gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag cgacaatcaa
    76741 ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga ttgctgggat
    76801 ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga ctttccgcta
    76861 aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg ccggactttt
    76921 tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg cgttcgccta
    76981 ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt caaatgtttc
    77041 gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt ctttttcttc
    77101 ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag ctattttttg
    77161 ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt tgatatagcc
    77221 acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac
    77281 ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta aatgaatttt
    77341 agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg aatgtgacaa
    77401 aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac tcctcaatca
    77461 taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc ttgtgattca
    77521 gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaatcagct gaccctcggt
    77581 attagctcaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt ctctaatact
    77641 taggataaaa cgctgatttt acaacctctg ttaaacggtg ttcaatcagc tgtccttcgg
    77701 tattagctca aaaaacggca aaatatgagg aactattttt ccgtttgttt ctctaatact
    77761 caggacaaaa cgctgatttt acaacctcct gataaacggt gttcaaaagc ttgcatctgc
    77821 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatg
    77881 acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc atttgtagca
    77941 aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc acctgcaaaa
    78001 taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa tggtgctaaa
    78061 gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg ttgcagacct
    78121 ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa aaatcctgct
    78181 aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa taacagcaaa
    78241 caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa cttccgctca
    78301 agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc aaaaaataca
    78361 aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc aagtaaagta
    78421 aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt atgattgctt
    78481 aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt ttcaggtaaa
    78541 agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa aaatggataa
    78601 cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat tccgcagcca
    78661 agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat actgacgatc
    78721 gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc acgtaaccca
    78781 atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac gatgataaac
    78841 aatcctgtca tcaatgtttt tttcaaaccg atccgactag ataagaaacc tgtaaatagc
    78901 atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc agctggcgta
    78961 gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac tcccataaaa
    79021 gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt ttcttcattt
    79081 gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc tctattagca
    79141 tcatacatga tttattttac atgtcaatat gcacatgtaa aacgtggaaa ctttactgtg
    79201 atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag cctatatatt
    79261 attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc tgatcacaat
    79321 tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag accagcaggg
    79381 ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc acttgactga
    79441 tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc ctacgcaaaa
    79501 agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa cagctactgg
    79561 actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc aaaaaaaatt
    79621 gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga tccagcgcag
    79681 aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac aaatgcagca
    79741 gttttttgag taagggataa acagaacctt tctagaaata tctattgaag agcaaattat
    79801 cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac aggccaaaac
    79861 ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac aaaaagcatg
    79921 ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt gcttttagca
    79981 cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca atcacattca
    80041 ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt tccatgatca
    80101 caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa atagttaaga
    80161 tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt ttcgccagca
    80221 caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact agaccaatca
    80281 acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc atccccaaga
    80341 ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt gtaggcaatc
    80401 tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa atttctcgta
    80461 agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt acgctcgaca
    80521 aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat tagcttctct
    80581 aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag caacacatta
    80641 cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc acttaatgta
    80701 cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa actacggaca
    80761 agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc ttcagatgtc
    80821 atttgataac ccttttgctg atatacttga aagcttactt tcggagagag aaggattcct
    80881 tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt ttcaccgaca
    80941 atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa tgttctccca
    81001 cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag ttcaagagat
    81061 tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc tcctattttt
    81121 tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac actgtctttt
    81181 tgtttagagg aagacaaccg atccagtctg atttgttgct ttttcttttt actggacact
    81241 ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa tcgttttttc
    81301 tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc cttttgagtg
    81361 agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac ttcccagatt
    81421 ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag cgtaccataa
    81481 taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg ggttgttggc
    81541 tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc gatctttcgt
    81601 tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg gaaatgactg
    81661 gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg caggtagttg
    81721 aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc tattagtttg
    81781 agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc ttgctgatag
    81841 acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg tagatttgtt
    81901 atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa acaacaatta
    81961 tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac atcttttcct
    82021 actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc acctattcta
    82081 ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata catgtctttt
    82141 gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc agtcattttt
    82201 ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata gctactgaat
    82261 agtaactgaa aaccttttat tcgaacatag tgatcttttc tggtgctaaa cgaacagact
    82321 cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca taacggtctt
    82381 tatccaaacc aaatgcctct gccaactgat ctgcttcgaa tccaccaatt ggatttgttt
    82441 catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta gaatcgactt
    82501 tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg atcgcagcta
    82561 attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg ttgtagattt
    82621 cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca gaagaagtat
    82681 cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttgct tcctcgcttt
    82741 cagcgaccac aaagcgccat ggtttcatat tgacagaaga aggtgcagtc gtcgcttctt
    82801 tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat acgcgaacgg
    82861 atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt attaacctct
    82921 ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag tgttagaaat
    82981 tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc tttatggtcc
    83041 atttcacaat gcttgatttt cttctgggct ttttctgtta gcgctacata cacttcccgg
    83101 ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac cttcagatga
    83161 cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg tagcaatgga
    83221 ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc gatattttct
    83281 tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag gtgactaatc
    83341 tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat tgacttgtca
    83401 ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa aaaacgctct
    83461 caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa atgataaaga
    83521 aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga tagctcttct
    83581 gcagtagata attttacacc gccaaaaatt tccgaaatcg ccttttgcaa gaatcccgtc
    83641 gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg acaagatgtt
    83701 gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta ataagttcaa
    83761 ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt gatgcagggc
    83821 agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata tctccagccc
    83881 atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt accagttttt
    83941 tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa acttagacct
    84001 tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat tgtgtaatga
    84061 tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt tggtgcttgc
    84121 caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc tccggcattc
    84181 aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg agaagttgaa
    84241 gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt caatgtagaa
    84301 ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc tttgtaagag
    84361 ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa agaagtcgtc
    84421 ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt tctaaaagcg
    84481 gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt aacagattgg
    84541 ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc caaagtactg
    84601 ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata taagtcattg
    84661 gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg ttgagaatta
    84721 gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga caaatctgct
    84781 tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc ttctgcattc
    84841 tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg ttctgttgtt
    84901 tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga ctgcaaagta
    84961 ctttctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt tgcgacagtt
    85021 tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc taaaagaata
    85081 acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat gaaacttttc
    85141 ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt aaataacatt
    85201 tgtttctttt taataaattt gctttttctg cataaaaaga cgtaaatgaa gaatattctt
    85261 ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt aattctctct
    85321 ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc atgttgctga
    85381 cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata tcttcagatg
    85441 ttaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg tcgctgatgg
    85501 tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg atgttatttt
    85561 gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt gttccgcaat
    85621 aaacggcgga atcaggataa acaacatgtc ccgccacaga atcagttgaa atgatatgcc
    85681 cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac acacccatga
    85741 tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat ggagcggttg
    85801 gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc atcgctaaat
    85861 cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata tatagctcag
    85921 cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca gctataacta
    85981 gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg cttgaagcgc
    86041 ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc tgttttgaaa
    86101 aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata atccgttcga
    86161 caggtttgac gattttggca gggattcctg caacgatggt attgtctggg acatctttcg
    86221 taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct ggcagaatag
    86281 ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact gacaagcctc
    86341 ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga ggaccaatca
    86401 atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga cgattgataa
    86461 agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc agcagaacag
    86521 tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg atatctgctg
    86581 gttcatggta cccagtattc agcgctgcta aaggctcttc gttttccgct tggatctgat
    86641 ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt tgtttttcga
    86701 tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg gcttatgatg
    86761 tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg gtatgctttt
    86821 ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttta gcagtagcta
    86881 gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat cacgcaacct actctctcaa
    86941 aacaactgaa agatttagaa gaagaacttg gtgtgacact tttcactcga ggctcccgag
    87001 agatacagtt gacggattct ggtcgatatc tttattcaaa aggaaaagaa atcttgtcgt
    87061 tggtagaaaa aacggcgaac aatttaacaa atgacgcaat catctctgga gaaatctaca
    87121 ttggcggagg cgaaactaaa gcaatctctt tcatttctga tagccttcat tcgttgatca
    87181 aggcgcatcc tgatatccag tttcatttat atagcgggaa tgcagatgat atcatagaca
    87241 aactggatag cggattactt gattttggac tcgtaatcga accgacaaac aaacaaaaat
    87301 accagtcatt tcgactgcca gcccaagatc gttggggact tttgatacat cggaatcatc
    87361 ctttagcaaa gcaaacagtc atccatccgc aggaactgaa aactgttcct ttgatcattt
    87421 cccggcaaac gtcagtggac agtcaactag ctgaatggct aggtttcagc atagatcagt
    87481 tatcgatcgt cggaacatat aacttattgt acaatgcttc tttgatggtc gataacggga
    87541 cttttggtgc attagctcta gatgggatca tcaatactta tgggacggaa aaagtattca
    87601 tcccactcga tccgccatta caagcttcac tgaatctcat ttggaaaaaa gaccagcctc
    87661 tttctcctgc tgctcgtaaa tttttagatg tcctaacgga gaaatacagt taagtagagt
    87721 ttttttcctt cgctttcagc tttttaacaa cgaataagtt aagcaaaaga tccaatgatt
    87781 aaataacata agtttcttaa tttgttcctt ccttttattt ctgataattc cagtaaatta
    87841 ctataattat aaaaaaagaa ttgacaaaac ataactgtct atataaaatt gattacgtta
    87901 acaataattc gtttcatgtg actagatcat actaggcatg aaaaatctct gaggaacatg
    87961 gtttccctag gaggtttttc gtgtctattt ttgtttggcc gcaatcaact ggtctagcaa
    88021 acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa atcaaaaaga tctttaatca
    88081 aaatgcagta ttggtagatg acggtggaca ggaaaaagta gctattggaa aagggattgg
    88141 atttgacaga aaaagaaatg atttgatttt tgatcgtgat gtcgaacgga tatttgtcat
    88201 ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat cagattgatg aacgcttttt
    88261 atttgcagca gaaacgatca ttgatcatgc ggaaactgtt ttgatggaaa agttgaatga
    88321 acatgtattg atcgctttga ccgaccacat tgctttttct gcggagaaca ttaataacgg
    88381 tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg ctttacagtg atgaattcag
    88441 tattgctcaa tgggcagtag agtatctgac aaaagagctt gggattccat atacttatga
    88501 cgaagcagga tatatcgcaa tccatattca cagcggacga agcggtcgga acaataacca
    88561 tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc catttagtgg aatcagaatt
    88621 ggaaacagat atccattcag aaccattttc actgaattat tcaagactgg tgaatcattt
    88681 acgactgctt ctacaacgaa cccatgcgca acaatatgct gttttagaca cggaaatcgt
    88741 agaaatggtc aaacgaaaat acccagaaag ctataagatt tctaaaaaaa tccgtgtgtt
    88801 gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa ctgggttact tggccatcca
    88861 tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt aacaatcatg aggaggaaaa
    88921 aaattgaaag catatctaca acgaatggga cgttcccttc aacttccagt tgcggtctta
    88981 cctgctgctg ctttactagt agggatcgga aactggtggg catcttatag taacgacatt
    89041 gtcgctcatt ttttacaagc tggcggtaac gcagttttag gtcaattacc tttgctgttt
    89101 gccgttgggt tagcactagg gatgtcagtg gacaaatcag gtgctgctgc cttggcaggt
    89161 ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg attcagtagc tactttattg
    89221 aatatcaaac cagaatcagt tgatccatct tttgctcaga tcagtaacgt atttattggt
    89281 attattgccg gattgattgc ggcagctctt tataatcgtt tccacgaagc aaaattaccg
    89341 atggctttat ctttctttag cggcaagcgt ctagtgccaa tcttggctgc ctttgtcatg
    89401 ttgctgatca gtgcagtgct actgctcgta tggcctccgg tttactctgc tttagtttct
    89461 tttgctaaat tcattttgag tttaggctgg ggtggtgcag gtctttatgg cttcttcaac
    89521 cgtttactga tccctacagg attgcatcaa gcaatgaact ccgtgttctg gtttgacgta
    89581 gcaggaatca atgatattgg taaatttttg gcttctgaag gaacaaaagg cgtaacagga
    89641 atgtatcaag ctggattttt cccaatcatg atgttcgggc ttccagcagg agcatatgct
    89701 atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag cttccttgat gttagcagca
    89761 gcttttgctt cattctttac tggtgtaaca gaaccacttg aattctcatt tatgttcgtt
    89821 gcttggccat tatatgtctt gcatgcaatt ttcactggga tttctttagc agtgagtgca
    89881 ttcttccatt ggacagcagg atttgccttt agtgccggat ttgtcgatta cttcctatct
    89941 ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg tccaaggatt agtaacagca
    90001 gtgatttact actttggctt taactttgct atcaaaaaat tccatctgat gactcctggc
    90061 cgcgaggaag cagatctttc agatgacgat actgcaacga ctaattcaga caataaatat
    90121 gcggcacaag caagcaaaat ctacgctgca ttaggcggag ccgacaatgt aacttcgatc
    90181 gataactgta ctacacgcct tcgtttgcaa gtcaaagata caggcctgat cgatcaaaat
    90241 aaaatcaaag ccactggcgt acctggtatg aagatcatcg acggaaaaaa tgcgcaagtc
    90301 atcgtaggta cagaagtaca attcgttgca gatgagatgg caaaactaca tggtggtgct
    90361 gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag aaacatttgc cggtggaacg
    90421 atcgaacaag atatttacgc tatcgcaaat gggaaactga ttccaatcac tgaagtttca
    90481 gatgatgtat tcgcggaaaa aatgatgggt gacggctatg ctgtattacc agaaaatgga
    90541 gaaatcttct ctccaatcgc tggtacgatc acaaacattt tcccaacgaa acatgctgtc
    90601 ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata tgggcatcaa cactgttgac
    90661 ttaaaaggcg aaccattcac tttatatgta aaagaaggtc aaaaagtcgc aagaggtcaa
    90721 ttgattgctt tagttgatct tgccgctatt caatctgcag gcaaaaacac ggatatggtc
    90781 gttgtattca caaatggcga caaagtccaa agcttagaaa tcgaacccgc acgtgatgta
    90841 aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct gagccatcgt cttccccaga
    90901 cttttttatc gataaacaaa caggagctga gacaaaaatc ttgtctcagc tcctttttcc
    90961 gaataaaaac ggcgttctcc tgccaactcc gcggtaataa gtccagccaa acgtaacata
    91021 tgaagagcta ttttttattt gactcttctt attacttgat gcagaacagc ttttttacaa
    91081 cctctgataa acggtgttca aaaaccagtt tatcggtatg aagtcaaatt tatgcaaaaa
    91141 tgtggaaagc cattttcaca aaatttttct tcatactcaa aactaatcgg ctttttcaca
    91201 acctctttat acattattcc tgatccaata tttcttttaa tgctgcttca agagaagtta
    91261 atggttttcc caatactttt tctaaatcat cagaggaaat agctaactga tcctttttaa
    91321 tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg agggaatccg gcttctttta
    91381 gattttcgac aaacgctgca tcacttgctt caataatttc taacttttta cctgtcgcac
    91441 gctctaatgc cttggctaat tcttcatagt cagttagatt gccggataat tctaagattt
    91501 ctggagagtc actttctact agtacttttg ctgcagcttc tgcatattca cgtttcaatg
    91561 cccaacctgt ttttccattt cctgcagcat aaacgaattg accagttttt aaagcctgcc
    91621 caatgatagg taattcattc tctacatacc aattattccg taaaaatgta tgggaaatac
    91681 ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt
    91741 gatcggcatc tgcaaaactt gtataagcga tataagatac cccagctgct tgtgctgcct
    91801 tcactacatt cttatgttcg gcttgacgat ttcctggaac gccagagaca aaaagcaatc
    91861 gatctattcc tttcaacgct tctttcattg agtctaaatc atcataatca ccaatacgta
    91921 tattaaatcc agcttctttc agtgcttctc ctttttcttc actacgtact agtacataga
    91981 tttcattttg tggaaccatc ttttttaaga attccagcgc ataaccacca aaacctccag
    92041 ttgctcctgt tactaaataa tgcatatttg ccactcccta ttctttttat ttgttaagat
    92101 ttacagctgt acatttataa attacacctt tatcataaag agtgtggtaa gataagtcaa
    92161 gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc tgcaatttag tgatgcaatc
    92221 catgtacttg cctatattga aatgtttcaa gatacccgat cactttctag tgagatgatt
    92281 gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa
    92341 tccggtttga tctttacaaa aaccggaaaa ccgcagcctt cccttgccaa aagtccagat
    92401 cagatttctt tactagatgt ctatcgcagc atcgaaggta atacacagct tatccaagtc
    92461 gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa
    92521 agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg ctaagatcac acttgatagt
    92581 ctgatacata aaatagccgt tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta
    92641 gagagatttt tataattctc tctactgtgc ctgcattttt ctgatcggaa tcgtctacat
    92701 aaattctttt attctccggg ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc
    92761 tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg tgttcaagta gctgaccctc
    92821 ggcattagtt ctgaaaaatg caaaatatgg aaagctattt cccatttttc ctctctaatg
    92881 ctcaggtcaa agcgctactt tcacgacctc tatattatca tggtttattg actaccggta
    92941 tccagatttc tcccatatat ttcccgttgg taactcccat ttcgactaca gcatttggac
    93001 ccccaacata ggcgtaatct tctacttctc ttaaaacatg cccaaaggcc gtattcgtca
    93061 aatcatttct taattcttca ggcgattctg ctaaagcgat tacaacaaga tacgttcctt
    93121 ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg actcgtttga acaccgacat
    93181 agtacatcat tttcccgtta tagggttcgt tgactgtaaa gaaataatga ttttcagcag
    93241 cttgtttcaa tgcatctatt gttccattac cgataacttt ttgctcaaat gcttgtttct
    93301 ctgcagccaa accgacaaaa tccgtattgc tactcttcaa ttccacacca atacccgtca
    93361 ccgtaaaatc tggtttttct tcgatcctat actttgccat ttctcccacc ctttctatta
    93421 tattaagttc atcttacata aaattaaagg gaaatgacac gattacgctc ttttttctag
    93481 ggatattttt attttttaac tatttttttg ctttcactgc aatccaaatc tcactgtaaa
    93541 cattactgaa atcctctccc cattttgtaa aagagatctc gggagcttcg actaactcat
    93601 aatctgaaga aggaagccat tctgcataga ttttccccca agtatcttgt aaagtttggg
    93661 gaaatggccc tttattagga aaaatggccc aagtgtgttc ttctatagca agcatttcta
    93721 aatcagcgta cggattttct tttgtcgtag caaagccaat catgtgcatc aaactgccct
    93781 tttcttccaa gcgggctcca tcaaatccat aagaaacgtt gattacttga tttggatata
    93841 aatctcctaa cttatgcatc tcttcccttt gagtctccgt gatcgtctgc gctaactttt
    93901 gtatttcttg attgactcct tcaaatttga caggaacttt tttcgccaca cctgccacat
    93961 aaaactgttc tttcttttcg atacgaaatt ccatcgattt tcctcctctg acatcaataa
    94021 aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct gctgatttct gaaggcagat
    94081 atcctgacca atcacgaaaa gctcttgaaa aaccttcgac tgtttcatat ccatatctaa
    94141 acgccgtttc tgtcactctt gatccatcta ggagatcgcg attagccaaa gccaatctac
    94201 ggtttttgat atagtccatt agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt
    94261 gatattcaga gattcctgta ttttcggcta ttattttata ggaaagtcct tctgtcaaat
    94321 gttcttcgat gtaatcgatc aattggttca gatctttaag catatttatc ttcctccttg
    94381 cttgcctttt tatcatatta tcaaagaaag tcaattactt gatgaatcag gaaccaattt
    94441 agtcagatgt agaaaatgtt gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac
    94501 ggataattgg tattatctgc ctatctatgt tttaccttta gaaaaataaa ttttggggaa
    94561 gacacattct aagtaaacaa agcggtaaaa atatctttta ttcccttagt taatccgctt
    94621 actacctact gtacaaagca aattgttgtt caaactgctg atcagaacgc tgcttggatt
    94681 tttctttgcg atacatcata cctcttttat caattggaac aattatttat ttctaacaaa
    94741 atcacttcat ttttgtcaga taaataaaaa acaaaaaaag ttccatcttt aaaacacgct
    94801 attcttttac tttttctcac attctctaag aaaagaaaag gagaatgaat ttttgacaat
    94861 tcgagcaaaa gtgattatca aatatgtaaa atcagctact tttttcttaa acgtttcttt
    94921 atactaaata taaataagtg tttcatgaaa ggagaactag atgaataatt ggcttgagta
    94981 ttttcctgaa aacgttttgg aacgcggtta cagctatcat ctgcacggtt ttgtccgtca
    95041 tttgaactat acaagcaagt acttgtccgc aacagtttct ggcacggaag attataaggt
    95101 agtgatcact tgggatgaaa agaccaacat gacttgtgat tgtctatatg ccatagaagg
    95161 aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac gaagaacgtc caataaaaaa
    95221 atccaactac tcactttccg aactctcgtc ccttgtttcc tccgctagtt cctctcttgt
    95281 acgggagctt ttaacagaga ttcttataga acatccgcaa tttatcgaac gcttcaaagt
    95341 taagatgcca tttcatgcaa taaattattc agataaatta acaactatca tccataaata
    95401 cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg aagttcatca tggagatgcg
    95461 aaagttcatc caagaagcag ttgaatcgct cattcagcaa aatgcctatc ttcccgcatt
    95521 cgaattgatc aatgaagtga ttgctactct cgaaacattc tattgggagc ctgaggatga
    95581 acgaaccctt cttctgatag aggactgtta ttatttatgg aaagaattat tagcagaagc
    95641 acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc tgccaagtcg atcatactga
    95701 cgcctcttat tcaaaacgct actccataaa aatcctgaaa gaagactttc gggaaaaaga
    95761 attttctaac caaaagaaaa aaatagataa aaaaactaaa gaaacggtaa agaaagacga
    95821 tttcaatgaa aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc
    95881 agaccttgct ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta
    95941 cccaatatta gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt
    96001 ccttcgttgc tgggtagatt ttccggcatt gttgatagat tttatgatac ttttctacat
    96061 tttgtaagag aggttccact gcatctgtat attggataaa attctgacaa caactttcag
    96121 gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa ataacgatta ataatattaa
    96181 cagtctttat ttttcaccac caaaaaccta tctttgcata tactaaatag acgtatatac
    96241 acagataggt ttgtcttgtg aaaaataatg attatcctta ccaaaaaatg tttgtttttc
    96301 tacatgttcg tacttatcaa aaaatatgat ccttattgaa attactggct atttatattc
    96361 caacgacttc ttgtgttaat ttttgttatc tcatagtaaa ttatgtttca ttttcactta
    96421 atttagttgt cacgtgttcg tcaattcgta aaaacggtaa atatataaac acacttgcgg
    96481 ctataattaa tatttgtaaa acagctgctc gccagtctcc ggctgttgct aaaaatcccg
    96541 atataactgg tggcgtagtc caaggaattt gcactactac atgattaatt aatcccacag
    96601 cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc aagcacaaag ggaataatca
    96661 gactgatatt aaatacaata ggcaatccaa aaataatagg ttcgcttata ttgaatatag
    96721 cgggagttac cgataattta gcaaagtcct tataatcttt tctacgactg aagataaata
    96781 ttgcaatcaa taaagcaatc gtatttcccg atccacccat taccgcaaag gtatctttaa
    96841 aggccatatt gataatatgt ggaatttgct ctttgtttgc ataagctgcc atattttctt
    96901 gcatattctg aatcaaaaac ggatctaaca atgaacctga tattactgct tgatggatac
    96961 caaatccaaa aaatagatta gcaatagatg taattaacaa aaatcctggt aaaccagttg
    97021 taattttact taatggctct gtaactatcg tggtaattag cttatttata tccatattaa
    97081 acaattgaat gattataaat gacaataaag caaacgaggt aatcgtaata atgattggga
    97141 ttaatacatt aaaagacttt aaaacagcgg gaggaatatt tccggatagc tgaatctgta
    97201 gtttcttatt attagaaagt ttaataaata attctgtagc cgctaatcca acaaatatac
    97261 ctacaaacat tcctgaagct cctgtatagg atataggtat cacacccgtc acttcaacag
    97321 ctttatccgc attttcagga gtaaacatca tctgcatagg tgttaataca acaaatgtcg
    97381 aaatagcaac taataccgct gcaatatgat ttgtataatt tctgcttgca cacatatgat
    97441 aagatactgc tgctacaact aataatgtag ttatgcttaa tgtaccattg gcaattgaag
    97501 taccaatttg ttgtaacgtg gtcaatgtac tagtatcgac aatttccccc atgaatcctg
    97561 ttggttctaa gatcactgaa ttaataagtg tcacaaatcc tgctaacatc ataaatggca
    97621 taaatgtagc aaacgcatct cgcaaagttc ttaaatggat ctgattcccc aacttagtcg
    97681 caactatacc aaatttttca aatacaatgt ccttcctgct acttttgccc atattttttc
    97741 tcctttatgc ttattgtaat cgattacttt ttccacccaa ataatacatc acttatcaaa
    97801 aaaagtaaat acttttaatt aaatatatat atctttttta gtataaaaaa ataagctctg
    97861 aaaaaataat tttcccgagc ttatttttca acaaaaacag cttcaaaaac aaagtcttga
    97921 tataaatgtc tcgataccga atactcgaaa ggtttaccag acgatagagc aacaactttg
    97981 tctatctcaa tcataaattc acctggatct atttttaata tttttgcgtc aaattcattc
    98041 gcagtatctc ctttgatacg tatgtgcgaa gtctttattt ccagacccag ttcatttgtg
    98101 atataagcat atacagattt ctttaaatgt tttggttcca agcctggtat gactgctaat
    98161 ggcatgaatg tttgctcaat cgagtatggt tgacaatcaa taaaacggct tcgtacaata
    98221 ttatatacat agtcttttac actgatactt aatttatcag ctactttttt cgatggaagt
    98281 tcaattgaga aagtatggat ttctgaatct acgtgttctt caccaaccac gctaaacaaa
    98341 ccttcgtttg gaccaagaac tcgtgagtta tcaattggtg ttctgacgac ttcagtccca
    98401 tacccacttc tacttcgcaa aactccttcg gaaacaagta agtctacgcc tttctttact
    98461 gttaacttgc ttgtatgata aataactgcc aattcatctc ctgtaggaag tttctcacca
    98521 attttatact ctccatttac aatttttttc tttatatcta agtaaatttc catatacttc
    98581 gcaatttttt tcaatggtga ccctccaatc aaaaacatat cttcatctat actttaacat
    98641 aaataaaccg ataaaatcca catcaaaatt atacacacaa taaaaaagat atatatattt
    98701 aaacaaaact atttacttta agttgtaagc ggtgttatca ttaagtggaa acaggaggta
    98761 aaaaaattat gacaactatg aaaaagctaa cttttccaga tgatttttgg tggggttccg
    98821 cttggtcagc tgagcaagca gaaggaaaag gagaaacagg aaaagcagag actatctggg
    98881 atcgctggtt taaagaacaa ccttaccggt tttatcaacg aatcgattcc tctattacaa
    98941 ccgatcacat ccatcaatat aaagaagata tagaactaat gaaaaaaact gggcataact
    99001 cctttcgcgt ttctatttct tgggcacgaa tgtttccaaa tggcggtacc ggaaaagtaa
    99061 atcccaaagc catttctttc tatcgaaaat tattttccga aatgaataat aacggaatca
    99121 aagtatttgc caacttatat cattttgaca tgcctgctac tcttcaagat aaaggaggat
    99181 gggaatcacg tgaagtagtt gatgcttatg ttcattacgc tgaaacttgt tttaaagaat
    99241 ttggtgactt agtttgtcat tggtttacct tcaatgaacc acttgggcct attttaggta
    99301 cttatcttga agattttcat tatccaaacc tcattgactt taaacgcgga gcgcaagcag
    99361 cattcttcac tatacttgca cacgcaaaag caatacaagt atttaaagaa ctagctcttc
    99421 ctagtaaaat aggcgttatt ctaaatttga gtcctacttt tcctcgtagt caaaatcctg
    99481 ctgatgtgaa agcagcagaa atcgctgatt tattttatac gcggagcttt ttagatccta
    99541 tggttaaagg gaatttttct aaaaagctta tcctgttatt acaagaatat aatcagcttc
    99601 ctgaagatta tacgaaagaa gatcttgtat gtatctacga aaataccgct caaattcttg
    99661 gactaaacta ttacgagcca cgtcgcgtca aatctcgttc ttctatggtg gatacatcta
    99721 gtccattttt accagagtgg tttttcgaac cacatatcat gcctggacga cgaatgaacg
    99781 aataccgggg atgggaaatt tacgaaaaag gaatttatga tttgtgcatg gatatcaaga
    99841 accattatgg aaacatcgaa gcatttatct cggagaacgg aatgggcgtt gcggatgaag
    99901 aacgtttcat ggatgataca gggcaaataa ttgatgatta tcggattgag tatatcaaag
    99961 atcatcttgc ttacttatgg aaggcaataa atgaaggatg taacattaag gggtatcatc
   100021 tttggacatt tattgattgc tggtcatgga tcaacgccta taaaaaccga tatgggctgg
   100081 tttcactcga ccttactact caaaaaagaa caattaaaaa aagtggcgaa ttttacaagc
   100141 aattaagtga tacaaatgga tttagatacg atgtagactt gttagttgaa taatattcta
   100201 aaattccact tgaagtgaac acattagaaa acaagaataa tgagaaatac caataacaaa
   100261 tactttttct tcatacttca tttatacttg tcagtataag agactgtgac aaatgtagtg
   100321 atcctcagaa gttaggtctg gaaatctaac ttgagaagat ttttttaaac tacgtccagt
   100381 cttttttatt tgtttaaaat tgaagttgac aagtcttcat taaaaattta gaatattcac
   100441 aagtttgacg acaattatga aaatttatgt cgtgctaaag gagttttgtt attggatgaa
   100501 aagttagata taaaaactgc gatcaaagac acgttaccta ccgtttttgg ttatatcggt
   100561 attggacttg catttggtat cgttgggaaa gctgccgggt ttcatccgct ggtcgtcacg
   100621 ttgatgtccc tgctgatcta tgctggttct gcccaattta tcacggtcag catgcttgct
   100681 agccatagtc cactgctctc catcgttctc tcgacctttc tagtcaattc ccgaatgatt
   100741 ctgatgagta tgacgattgc tccttatttc aagaaaaatc ggctgcttca aaatctgctg
   100801 attggcacat tgctgacaga tgaaagtttc gcactgggaa tgaataaatt gaactatact
   100861 ggacaaaagt taaactttcg ttggatgaat acagctaatt ggatttctta tttgacgtgg
   100921 gtgggttctt ctcttgttgg cgcactttta gggaatttta ttactgatcc gaaaaagttt
   100981 ggtttggatt tcgccatcgt cgctatgttt atcgggttac tttatcttca agtcatttct
   101041 gatagaaaca cctctaaacg attacagttg atcctgattg gtctcacttt gattctggta
   101101 tatgtcggac tgatttttat cccaagtaac ttagtgattt tagttgtaac actgattggg
   101161 tgcggattgg gggtgtggat caaacatgcc ttcttttgag tttacattgc tgactatttt
   101221 aggttgtact ttagcaactt ggctttctag gatcctacca tttgtcttac tgaaaaaatt
   101281 cgatttgccg caaccgttgc ttgagtattt aagttttgtc ccgatcgtca ttatgtctgc
   101341 tttatggttc agcagtctat ttacccaaaa tatcggacat ctgccgcaga tcaatctcga
   101401 aaatgctttg gcttcagttc ctacactttt agctgctatt ctttcaaaaa gcttattggt
   101461 gatcgtcttg gtaggaattc tttccctttc gttgattcgc ttattataaa taaaaaaaca
   101521 agagcttatg gcaaattact gtcatgcgct cttgttttta tcaaagtcaa ataagaaaaa
   101581 aatcggcgta ttcttgctta tccgttgaac ggaccactaa caacgacttt tcctaatata
   101641 tgtcctgttt ctacgtcttt ggttgcttgt ttcaagttct tcgcattcat cccatctgaa
   101701 tagaccttgc tcaatgtact gcggataatc ccttcatttg ctaaagcagc aatgtgcgct
   101761 aaagcttctc cttgcgtttc gatttcatag ttatagtctg ttttagcgaa catatactcc
   101821 cagtcgaagc tgatagattg gtttttccaa acacctatat ctaacggctc tttgatccct
   101881 acgatcgttc ccacatgtcc aaatggtcgg acaaggtgtt tgatttgatc aaagtagcgg
   101941 gtaatatcga ataatacagc gacatactct acttgatcga ttcctaattc acgaaaactt
   102001 ttacttaagt cgtgatgata atcgattgga tagtctacac ctgttttttt cagccattca
   102061 aaattcttcg gacttgcagt cgcgtagact tctaggccag cccaatgcgc tagttgattc
   102121 aaaatcgaac cgacgccccc agctccgttg atcactaaga tttttttccc gcggttggca
   102181 ttttcttctg gagtcagacc aaatttttca aataacaatt cataagcggt caatgaggtc
   102241 aacggcaagg ctgcggcttc ttcatctgaa agattttttg gtgcaagagc gacaatacgt
   102301 tcgtcaacca gttggtattc ttgattgctt cctgctcttg tcgttgtacc tgcgtaaaaa
   102361 acgcgatcgc cgacagaaaa tttttgcact tcatcaccta cagcaacaac tttcccgact
   102421 ccatcaaacc ctaagatacg taaagcattt cttatcccgt tatcttggcg aagtttcgta
   102481 tcgacaggat taacagatac tgcgttgact tttaccagaa gatcccgtga actgggtaca
   102541 ggtatctgtt ctttttcatc aataaagctt tttggatcat cgatcgacaa cccttcataa
   102601 aaaccgacta ccttcattaa ttccttttct gacatacgaa ttcctcctta gcttcatcaa
   102661 gttggagcat ccatacagtt ttcatttcaa tatatatagt atgctatttg ttccactttt
   102721 attcatcata attattctct tacttaaagt aaactatttg cacttttttg gttaaaaaag
   102781 aggttgcgac aagacttttg tcacaacctc ttttaaacgg tgttcaatca actgaccctc
   102841 ggtattcgct caaaaaacga caaaatatga ggagctattt ttgtttggct gttcttatta
   102901 cttgatgcag gacagctttt tcacgacctc taattcacgg tgttcaagca agaaatcatt
   102961 gttcactgaa aagcgttgga tgttcttttt caaaggtgtc taagatctct cgtacttcat
   103021 cagtagattt cgtattcatc aactgaactc gcaagtcatt tgctcctgga aatcctttga
   103081 tatagatttt aaagaaacga tgtagtcctg tgatggaacg cgggatgatt tctgaataat
   103141 gatcttgcag atctagttgc agacgaagta gtccgatcag ttctttttct gtatgttccc
   103201 tcggttcttt ttcaaatgca taaggattct tgaaaatccc ccggccaatc atgatgccat
   103261 ctacgccata tttttcggcc aattcttctc ctgtctggcg atctgggata tctccgttga
   103321 tcgtgatcag tgtttgcgga gcgatttggt cacgtaaagc aatgatttta gggatgactt
   103381 cccaatgtgc atctacttta ctcatctctt tacgcgtacg caaatggaca gaaagattgg
   103441 ctatatcttg atgaagtagg tgactgatcc attcttccat ctcagacatt tccgtatagc
   103501 cgatacgcgt cttgacgctg acaggcaaac cgccagcttt agccgcttca atcaattgtg
   103561 ccgctacttc tgggcgaagg atcaagccac tgccttttcc acgttctgct acattaggga
   103621 ctgggcagcc catgttgata tcgattcctt ggaagcccat ttctgccata gcaatgctca
   103681 tttctctaaa aaattctggc ttgtctcccc aaatatgggc aaccatcggc tgttcatctt
   103741 ctgtaaaggt caatcttcct cgtacactgt cttttccatc tggatgacag aaactgtctg
   103801 agtttgtaaa ctcagtaaag aagacatccg gtgctgctgc atgctttacg acatggcgaa
   103861 atacaacatc tgttacatct tccattggtg ctaaaacaaa aaaaggcttt ggcagctctt
   103921 tccaaaaatt agtagtcatt tatttgttac tctccattct atcaagcagt gaagtcgcaa
   103981 tctttctcaa aaacattgtc attatactag gaaacaaaaa aagaagcaaa gtgaacagct
   104041 taaaagatgt ttctgattga gcaaaaaaag actgtgacaa aaatcttatc acaattcctt
   104101 ttccggaata aatggtgttc aaaagcttgc atctgcggta ataagtccaa ccaaacgaaa
   104161 aataggagga gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca
   104221 caacctctcc actaaacggt gttcaatcag ctgaccctcg gtattagctc aacaaacgac
   104281 aaaatatgag gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt
   104341 cacaacctct tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg
   104401 cgtacaaaac aacgatgaat agcacaagta cgatcatcga tgttgctact ggcacatcga
   104461 ttgttccaag gaatccgtaa cggaaaccga agatcatata aacgatcgga ttgactttcg
   104521 aaacagcttg ccaaaatggc ggcaacatag agatggcata gaaaacgcca cctagataag
   104581 ttaacggctg caagacaaat gtaggcacga tcgatacatc gtcataagac tgagcaaaaa
   104641 tcccgttgag cagtcctgct aacgaaaaca agattgccgt catcaataat gtaatgatga
   104701 ccatgaacca tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag
   104761 agccgacgag aatactgcga cccactccgc caatcacaaa gccccaaatg atcacatgcg
   104821 taggaacagg cgctaccaag atttcttcga tgtttttctg gaatttttga gagaagaagg
   104881 acgaagaaac gttggcatac gaactagtga tagcagacat cataatcaaa ccaggcacga
   104941 tgaattccat atatgaaaaa ccacccatgt caccgatccg accaccgatc atttttccga
   105001 aaataacaaa gtacaaggat gtcgtgatca caggcggaac cagtgtttgg acccagatac
   105061 gcaaatagcg gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa
   105121 acatttttct cctccgtatg attattttct tctgtgattt tcaaaaacag ttcttctaaa
   105181 cgattcgact tattcctcat agaaagaact ttgattcctt gtcttgtcag ctgatcgaag
   105241 attccgttca ccccttgatt tcgttcaact tcgacagcga ttgtctgttc atcttcaaat
   105301 gtacaagcgt atccttcaat cacaggtttg gtctcatatg gcgctaaatc aaagataaat
   105361 gtttcaaatt gcagtttgga tagaagctct ttcatactag tattctcgat cagttcacct
   105421 gattggatga tcccgatgtt gcgacaaagc atttcagctt cttctaaata atgcgtcgtc
   105481 aaaatgatcg ttgtaccatt ttcgttcaat tctcggagaa actcccacat ctcgcgtctc
   105541 aattcaatat cgactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc
   105601 aatgccctag caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca
   105661 tttctctttt cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct
   105721 ttgcgagaga caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaag
   105781 ggattgaaat tgaactcttg cgggactaat ccaatctgtt gctttgctcg gactagatcc
   105841 gtatccagat cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta
   105901 atgattccga tcgttgtaga cttcccagct ccatttggtc ctaatagcgc atagaaatct
   105961 ccttctttca cggaaagatc gattcctcgc aatgcttcga ccccacttcc ataaaccttt
   106021 ttcaaattat ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat
   106081 tctttattgt atcatggaat acagcagatg aaaaaacaac ttggttccag cgaaaaatca
   106141 ggttgctggg ctcaggaaaa tctcctaatg aaagacatca atcggacgaa gtcagacaac
   106201 cttttcagaa aaaacaaatc gaagataaag gattactatt catatgtgca acaaaaggag
   106261 cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa
   106321 gcaaaagcca agatttttga tccaataaat actttcgatc acttcgccta tcccaataca
   106381 tgccactgcc gcttttcatc aaataacgcg gcttccgttt ttgcggtttc tactaaagtc
   106441 tctgggtaat ccaaaacttt cagcaaggca atcgcatttc gggtccttga aggtccttct
   106501 tttaatttga aatcaaaact gattcctttt ccttctgtta cttgttcttc aaagtggaca
   106561 ttctcacaat aattctttaa aatctctgtc aattcgatat catgtgtggc gacaaatgct
   106621 aaagatggat actccgcaag ccaccgaacg actgaagcgg aagaagcaat ccgttcgatc
   106681 gtatttgtcc cttttaaaat ctcatctacg aagcagtagc agcgttcttt ggaagccact
   106741 tggtccaaca aacgtttgat cgatttgatt tctgaaacaa aataactgtc gccttcaaat
   106801 aaatcatctt cgattgccat ggaagtcaac acatgtccag gttgcagggt aaactgttct
   106861 gcaatcgctg tttggatcgt ctgtgctaga atacagctga tggctatact tttgacatac
   106921 gtagattttc ctgatgcatt ggaacccgtg actaatgtat tcttctgcca gttgaccgga
   106981 ttcactaccg cttcttttaa caatggatga tagatatctt tcgctgtcac accgccctca
   107041 gtaaactctg gtcggcaagt gatgggcata taagtacggt aattcaatat tgcagcggct
   107101 acttctaatt ctcccagcaa ttcccacagc ttgatggctt cagttgaatg cttttctaat
   107161 ttagtgagaa cgaaatgata ggagataaat ggcagcatga acatgatgtt gacatattca
   107221 aaaatcaact ctgcttcact cccactcttc atacgaaatg aaaaacctaa tttagggatg
   107281 tctcttaatg gtttagtttg ctgtttcagc tcttcttgaa gtggtgtcgg cagttttgct
   107341 agctgattgg cggctgaaat cgttgaaacc aaataactca tgctattcag ctctgtttct
   107401 agtgtttgtt tcttcactag ataatagacc gtattgaata ctaacccacc gattgccaaa
   107461 tagattccta gtacttgtcc taaaagaagc aaacccaaac ccaccagcgg aagcaagcca
   107521 agaaaaataa ataaacctac gcgtccaatc tttttacttt ttccatccgc tagatattgt
   107581 tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt gatattggat tttttctctc
   107641 agttgaggat tttcctgata aaaagcaatc agtttttcta actgctgatc ttcaccaaaa
   107701 tcaaagctgc gtaaacgttg atacaacgct tctgaaccta cactagaata ggtactgttg
   107761 attccttcga atacttcgaa catatccagg tcataccaag taagatcatc gatttcgcta
   107821 tcccatgaac ggaacttctt ctccgtgagc catgcttcct tcaagctttc ttctttatca
   107881 aatctcggtt gataaggaat tttttcccat ttgctacgaa ctgtttcctt taatttcaaa
   107941 cgtgaaaaaa tgtctaaagc aactaataaa ataacagctg caataataat taaaacgata
   108001 aattctcttt gacccatatc cctctccgtt cctttatttg ttagctttag tatagcactg
   108061 ttgcgctatt tgaaaagagg gtaaaaaaac acctttcaaa ataaaaggtg tttttttctt
   108121 gtatattaca tatttatctc tcatttatca aaattgacaa ataatcatag ggaggaattg
   108181 ttgttaattc ttgtttattc tccagtgcat tgacaactgt cccaagggaa aggatagcct
   108241 caggtactat tttttcttgt tctgttggat tagctaagcg aagaacaaat ccttgttcat
   108301 gaaaataaga aggataaatc gatgatacaa ttaagtcttc aggtaattca atcaatgaaa
   108361 atttacgagg aacatcaagt tcattttgta atggccaaat cttgttatct aacctgtgaa
   108421 taaatacatt cagtttctgc ttttgataag aaatagattg ttctaaccgt ttttctgcct
   108481 gttttgccac tttgaactca ttaaatcttc cttcttctac attaaatcca aaagtgactt
   108541 tatactcacc tatctcttga gctagcggtg tttccatcat gacatgccct tcatttgtcg
   108601 tatctcctga agctcgccca ggtcgccaag caagattagg ttttccaagt tcccctgttg
   108661 ttgaaaataa ggttatgatt aattgatttt ctatacgttc atactctttt aaaccatctg
   108721 cataaaacgt aaaataatga tcattttctg ccacagagac actcttatcg aatatttcta
   108781 aattaacagg tttctctacc atagtttctg accaattcgg aggaatgaca tcaggggtat
   108841 tttcaataaa tccgttttga atttgtgcaa ttgatttttc agatttatct aaaacattaa
   108901 ttgctaagcg catacgatgc gagtaaacag tattatgaat tttgagtgtg ccttcaacga
   108961 tttgactttc tcccagactg aacgatattt cataagatat ttcttccatt tcgggttttt
   109021 cagataaacg atcttttaaa tctttaggaa gttgagcttt tccgtaaaca actaatgttt
   109081 cttgtaaaga atctttatat actttagctg tttctaattt tagagatagt tctgtatctc
   109141 cttctaatgg tgaataatca tacgtatcgc catcatttgc tgaatcgatc aaatgaacga
   109201 aatcaagata ttgtctatct ccaactatca aattcaattg cccatcttta aaagaaagtt
   109261 tatatttatt gttacttatc tcagttttgt ctatctcgat tgctgtttct aatttttcat
   109321 tatttttctc aaattcaaca acagtgtatc ctagtgctgg cacatttaca tttattttta
   109381 tgtcaagttc ataataagct ggttcatcaa aatattcgaa acctgtagca atcatccgat
   109441 aagcattttt ccgttctgga aaataaactt ctttttcaat gatattatag ggactacctt
   109501 tgaagtgtat tttctttgaa tcagctacta catgcacgat tttcgatcca ctataattct
   109561 cagtcgttgt gttgaaaaca aggacttcat tcgattttag ctttaatgca tcagccatcc
   109621 gttttacaat aaggttttcg attccgtcag ctatctcatt agcttctttg attcgatgga
   109681 aaatatcttc cgcaacatta tctgaaacac agccaccaat actatcatga gcctggtttt
   109741 gcaaaatctt tttccataac cgacgaagta ggcctttact gatatggata ccatttcttt
   109801 ctgcaatcag catgagcggc tcaactcgtt ttagaatttt ttgttccaat ttaaaatttt
   109861 ctattttcat ttttgttctt actgagccaa tagaacgatg aacacgagag taaaccggct
   109921 gacgaagttc acctttatat tcaggtaatt cttttttgtt tctgataact tctacataag
   109981 aaggataatc tgaaataata ttgtggaatt tactgtattt attcaacttc tctacgactt
   110041 gatcaaaatt taaaatcatt gacttttgat ctacacccga aggtactaaa atatctttgt
   110101 tttttccttg catatgaagc atttcaactg cttcatccaa cttttctttt gcaaattcag
   110161 gaatatcttt aattgcgtct aaggtcatca ttccagtcat ataaccaaat ggaaaattca
   110221 tggcataaac aaatttatct cccaatcctt tccagataaa ataaggagat ggaaccatcg
   110281 tttcaaagtt taatcctcgc caacacatga aattatcgat ttctacttga tgcaaaagtg
   110341 taggcaaatt cgcattgaac ccaaacgtgt caggcaaata ccctaccatc attggatctc
   110401 catatttaag gatcgtatca ctgattccaa tcattaagtt tcttaaaatt gattcagcat
   110461 ccactaataa ggcatctgtt tgtgcatacc acggtcccac gaatagttgt cctgttttca
   110521 tcagtcgttg gataacctta agcttttgcg gattgatctc caaatactca tcgacgattg
   110581 aagtttgtcc atctaaacaa aagtttactt tagggttcct ttccaattca tctagaactt
   110641 cagtaaagac ctgatcagac aatacgatgg catcttcatt tgtaaaatac cattctctgt
   110701 cccagtgcgt gtgttgaatt atatgtgcat ttaccatatc agattctcct actttccttc
   110761 ttctactgaa tttacttgtt gttctttttt atacttgatg gattttagtg cattgaccat
   110821 taacgctgta accactcccc caataacaat tgatactaaa tataaaggta tattcgtaac
   110881 aaaaggaatt gccataaagg ttgaaagcat tgtttcttga gtaacaccaa aaaatccatt
   110941 tagaccacat gctactgcag tgcccaccac gatgcttggt attactcgta aaggatcttt
   111001 cacggcaaac gggatcgtcc cttcagtaat ccccacaagg cccataatca tagctgtctt
   111061 tgcattatct cgttccgatt catcataaag ttttttgttt aaaattgttg ctaaaaacat
   111121 tccaaatggc ggaatagcaa ttcctaataa catggctgta ctaggtccaa agcttccgct
   111181 tgaaaaagaa gcaaccccaa aagcatatgc gattttattg ataggtcctc ccatatcaaa
   111241 cgccatcatt cctcctaaaa tagccgacat caaagcagca tttgctcctg acatgccttc
   111301 tagccaatta gtcagtcctg ttgtcattgc ttgaataggc gtagctagta cataccataa
   111361 tatgattcca acaactaatg tagtaacaaa aggaatcagc ataattgatt ttagactaat
   111421 aacttgcatc ggtactttta cttttttcaa tgcattagct aaatagccac aagctaatcc
   111481 agcaaccatt cctccaataa atcccatacc aagattttga cacatcatcc cagtgataaa
   111541 agctggtgct agaccgggac ggtcagcaat tgaatatgcg atataggctg aaatcatcgg
   111601 tacgataaac tgtaatcccg tctgaccaat cattcgcagg actccccaga atgtatccgt
   111661 ctggtcccaa acacctgtgc caccaaaaat gactgcaata gaagttagta accctgctgc
   111721 tacgacaagc gggatcatat aggaaacccc actttggaaa tgatttagaa tttctcttcc
   111781 ttgtttcttg aattccatta gtaactcccc cacgatatat tttttatttg ttaattaatg
   111841 caattgcttc atcaatcgtc tcttcaccat cttttactac ctctgaggtc cctactgtta
   111901 aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt tgtatctact gcaaatatga
   111961 caacatctgc ctcggaaaca tccgaaattg aaagtttgtt ttctatcccc atagccccct
   112021 gtgtttctac tttaatatct aaccctttct tcttcgcaaa cttttctaaa ttagcttttg
   112081 ccatataagt atgggcaatc cctgcgatac atgctgttac tgctactatt tttgtcatat
   112141 gaaattcctc cttttaaaat gatagagctt ttaccaattc ttttttattt ctcgaatctt
   112201 ttattctttt aacaaactcg tcatccatca atcttccaga taattctgct aaaatacgta
   112261 aatgattagt acctttatca gtgtctttta ttgctaacaa aaagacgaga tcaactggtt
   112321 gatcatctaa tgcgccccat tcaacagacc gctttaactt ggctacagcc actgttgatt
   112381 caattactgc taggcttttg ccatgaggaa tggcgatatt tttcccaatt cctgtggtca
   112441 tatggttttc tctgtcaaat acgtcttttt gaaattgttt gtggtcagac acaaacccat
   112501 tagtctctaa caatttcgat aatttttcga ctacactttt tttatcagat gcatttaaat
   112561 ctatcactat attatttata ttgatttttt cactgatcat ttataagcct tctttcaata
   112621 tataaactaa tttttcaaac gacgaactcg tttttaaatt tgctaataac tcatgattcg
   112681 aagcgatttc attgaatgtt tcataaattt tattcaattc aggttttact ttttcattaa
   112741 gtgcaaaaaa gaaaacagaa tgaacaagtg tcccatccca atcaattcct tctggattaa
   112801 cgtagacaca gattactggc ttttttataa aatctacttc gatatgcggc atagcaaaat
   112861 cattcatcgc tgttgaagat agtttttctc ttttgattgc tccctctagt atcccttctt
   112921 tcgcgtaatt ttcttttacc aattttttgg taattatatt taaaacgttc acttgattat
   112981 cctttatttg gtgggtaaaa aagcaaaatc gtttatctaa taaatttaga aaagcatctt
   113041 ctgtttgttc atttaactgt agatactgtt ttacttttct gacatctgcc cctaacatca
   113101 aaggactaac aacaataaca ggaaaatttg tattttcaat cggaatcgtg cttataacaa
   113161 gttcatcagt gacttttcta tcttgtagtt cattgatgct tagtacatct tctatctcaa
   113221 ccatatctgc aaaaccgtta tttattcttt gctctaataa ttttgatgtt ccatatccgc
   113281 tactacaaac taatatcact ttcgttttgt caggtttgta acgatccaaa agtgattgaa
   113341 tatggagtgt tacgtaagcg atttcatctt cattaaaatg tatacagaat ctctcttcga
   113401 tttcctctaa taaatctaca cttatcataa atgacctttt aaaagaatat ttgattttgt
   113461 ccgtataagg gttatagata tttactccca atttgagtct tttaactgct gcattgagat
   113521 gtaatactag attattgatc aattcttcat caggataaaa ttcatttaat ttaattctta
   113581 ctaactcttg tagctcaaca cccatatcta aataggaaag cttcgtttga tctaagtcgt
   113641 gattcatagc atttttttca atcgaagtaa tgtgaatgtc aacataagct tgttcatcta
   113701 ttggcacaat aattgaaaat gctttttcaa tcattttgat taaaataagt gtattctttg
   113761 agatttcttc ttcagaatta ttactacgtg ataagaaatt gcttgtttca atcctttcta
   113821 tcgcaatagc aaggtggata gctaaagttt gaaattcata atctgtaaat ttcaattgtg
   113881 tcttattcat gtatcgatta agcaattcgg ctactttttt caatatgtcc ttatttaaga
   113941 aattattcgc ttcaccaatg aaattgatat tcaagtctaa gagatctgtt ttactgttag
   114001 atgctgtaaa gccaccccaa taatagttca caacttctga catcaacctt cttttacttt
   114061 tttcatcagc tttgatgcgc acgccatttc gatctgaaac taaggacatc ccatgcttgt
   114121 ttagtctttt tctaacatct ttcattgtgc tttctaccgt cgacctgctc acgtataatt
   114181 cgtcagcaag attttgaatc tttagagaat cattagtatt caataattta gcaaacacat
   114241 aagttagacg gtcctccgga gagtctgcga tattgatttt atgactggat aataaatttc
   114301 gaagtgtttc tttttttcca ataagcgaaa cgcctttttt aggttgaacc aacatttgta
   114361 catctggcat tttttggatt atttctttca aaattaaaat atctttgcta attgttttcg
   114421 tagatacata taattgttct gataattctt tgtaagttgt gtgctcattt tcaatcaaaa
   114481 agtatagtat tttcatttgc cgttcgctaa attcgatgcc cattatcttc acctcctgaa
   114541 tacagcttaa gtgtacaatt attatctcta ttttcataca gaagaaagtt cttgattaat
   114601 gtagaagttt ctaatattct tgattatttc aaatcaataa aaaagcctgc aatatttata
   114661 tcacaggctt ttttctctat taaatatata taagataata catttttcta ctagttctca
   114721 ctaatcttgt ataattaaac cctccgcaac ttgacggaga tggagaagat gcccccgtct
   114781 aatctagcgg tcatctctcc tcccattcct tccaccaatt tttttgacag gtaaagcccg
   114841 attccgctag attccgtatt tgtgcggctg gtattttcgg tataaaaacg ctggaagact
   114901 ttttcaacag aggtttgcgt tcctggtttg ataggattgg ccactgttaa tcgaatgaat
   114961 ggatcctctt ttgaaaatgt cacctttgct tgtccatctg cataacgcaa taaattctgt
   115021 atgatatttt gcagcactcg cagcaacatg agcggatctg ctaatacagt tgtatttatc
   115081 gagtgttcag cgaacgctac ctcgatattt ttctcagaaa attgttcata aaaagagaaa
   115141 aatacttctt ccacctcttt agaaaaagaa agcgtatgga gatccatttc tttttgcttc
   115201 gtctctattc gagcaagatc ataaaactga tccgtcatac tgagtaatct tgcaacagat
   115261 tgtttgatga tcgttaaata cttctcccgt ttctccgtat cctctacctg ttccagtaat
   115321 tgtacataac cgttaatagc agtcaaagga gttctgagat catgagaaag gccgacgatc
   115381 gatagtctga tgttttcttc catttcttga aatgcttgtc ctttttgttc attttcatcc
   115441 aaccatgtat tcagtgcatc tactaggtcc attagattct tttctcgaaa ttcgactgaa
   115501 agacgaccac catattcttg tcgttcagaa agagtggcga ttttcttagt taatctcttg
   115561 atttcccttt gcaggaagaa aataaaactt cccataaaga taacaacgag aagcaacagc
   115621 catttaatca aatctaaacc ccactcccca caccgtatga atatacacag catgtgcctt
   115681 tgctagcttc cctcgaagat tggaaatatg catattcact gttttctcac tatcaaaata
   115741 tggttcttgc caaactgttt cataaagatt tgctcgcgaa aatacttttt tcggatgttc
   115801 taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa tggacagcca caccattcac
   115861 atttacatcc ctcgactctt tgtccagtaa gatttccttg taatagatgc gttgcgacag
   115921 atcttttact tggacagaag tctgatgacg aagttggatg ccgattcgta acaaaagttc
   115981 ttcgatatca aatggtttcg tcacatagtc atccgctcct gctgccaaca aggaaacttt
   116041 atctctttga tcgctttttg ctgaaagaac gatgatcgga acattcgatg tctgtcggat
   116101 ttctgctaac aatgcttcac ctgaaagccc tggaagcatg agatctagaa ggatcaaatc
   116161 gacaggatat gtgcttaaca ataattttcc ttccgtacct gaataagcat caagaagttt
   116221 gtatctctgt tcaagaacct cctccagtaa ggaatgaaca gcttcatcgt cttcgataat
   116281 caaaatagtt tccagcagga ccacctactt aatgtcagat ttttggaaaa taaacattcc
   116341 tagagctgat gataccacga ttgttactag actgaccaga atcattttcg gtgcttgcga
   116401 ataagttgct tgttgcgcaa agtccgtata catgagccac gtttccgtaa accactccgt
   116461 tagaaattcc aagcctttga tttttgcgaa aacaccggga atgaaggccg ttcccatgat
   116521 ataaagaaaa gaaagaagca aactgacact ggtacttcta gtgatgaatg tcaaagccac
   116581 tggaacagat aatgtcccta atgtcagcag aagcaataca ggaaatactt ttagaacata
   116641 atttccatag tttttgattc cctcaacttc accaaatccg aaagcaagtg tgtaagcaag
   116701 catggctagt cccgtgatca aaaccacgcc aagtgttgtg atcaaaagcg taacgagaag
   116761 tttcgacaca taataagtca ttcgattccg tcctaaagat aacgtattgc gaatcgtacc
   116821 gttttgaaat tcttccccaa tataaaagca cgcaaatgct gcgaaagcca gaagaatcca
   116881 tgcagccatt ttttctacca ttaaaatccc tgttgcaccg ttgatgactg tatccgttgc
   116941 ttggtttaat tcattgccgt attttgtatg catataccat tcgttccaag aataaaaaag
   117001 cggaagtacg accatcagtc ctagtgagac ccacatttta cggctcttcc atacttttat
   117061 tttttcagca gttaatagat taaacatgtg gattgcctcc agttaattgt aagaaataat
   117121 cttccagttt ttgcccaact aggtgaatac catccacagg aacttttgct tctaccaatg
   117181 cttgattgat ggctgctact tggtcaattc cttcaaaaag ctggataaca cggctagatt
   117241 gtacaaaata atccctataa ccaagagagt cgagaaccgt tactgcttgt tccgtcgccg
   117301 aagtgtcaat ttttataaat tgacgagatt cttgtgccaa ttcttctttc gataattctt
   117361 tgatcaagtg tccttcatgc aaaataccat agtgagtggc gatctgtgac aattcatcta
   117421 gcaagtggct agaaagcaag acggtgatgc cccgttcttt taccaaacgt tggatgattt
   117481 ctcgcatttc tgccatccct gctggatcca tcccattcgt cggttcatcc aaaatcaaaa
   117541 attctggatt cgtgatcagt gcatttgcaa tagctaaacg ctggcgcata cctaaagaga
   117601 aattctttgc tttctttttc cctgtatttt ccaatcgcat cattttcagc aggtcttcga
   117661 tttctctatc cgacacaccg ccgttcgctg cttggatacg taggttatct cttgcagtta
   117721 attctggata aagagcaggg gtttcaatcg attgacccat acgtcgtctt gctgcctgca
   117781 aatccgtcgt tccaaataat tcgatcgaac cttcatcaat cgagatcaaa cccataatag
   117841 ttctcataaa ggtagactta cccgctccat tttccccaat caatccatag atcattccac
   117901 gtttgatttc gattgatact ttatctaatg ctttggcagc accgtatttt ttggttatac
   117961 cagttgcttt caagaccgtt tcatttccaa aatccatact tatccttctt tcttattgat
   118021 gagtgaagta tagttgacgg gtataaagaa agcagccaga aatgtataaa gaaagtgtaa
   118081 attttccaat tgaatgtcaa aaaaaacaat cggacaatac gtgtctttcc tattatcagg
   118141 cagtttgtta tacgcttgta tcagtttcct gattctttct tttcgaccaa agtcgtttct
   118201 ctgtattcct cttcactgaa aatttttgct tctttcagat caagcttgag taattttacc
   118261 agaccggtta taaggataac tatagcaaga ctccctccca gaaaaattag actgtctcgc
   118321 agacgtggtt gcgttgtctt ccaatcaaag agcgcaccaa acagtgctaa tccaagtgga
   118381 ctggccacca tggtaatcgt tgttatcgtt gacataagtc gtccttgtat atgcgttgga
   118441 acttctcgct gaagccagac catataaaaa gcaaaagaaa acattaatcc ttaaaaacgg
   118501 acttatgaaa aataatacat gccgtttggg atttacaatt agctaccaaa taagaggtta
   118561 tgacaaaaga cttttcacaa tcccttcttc cgaataaacg gtgttctcct gccaactcct
   118621 cggtcacaag tcacaatatt tatcaaacat gagaagcaat ttttgtaaat tccttcttat
   118681 ttcttgaagc tgaccacttc tgtcacaacc tcagaagcgg ataaataata ttgtttgatg
   118741 atactttatc tttttcccgt ttgtttatag atcgaatgat attatagacc aagaatccta
   118801 cctattaaca tagctaaaaa cacaaaaaag gcactttcca aattgtggaa agtgccagaa
   118861 aagttaggat taaggtaact gcgctcagca ttgcttcgcc cagtacgatt ctcgtaactc
   118921 gtgaactcga acgataatcg caattaacgt tttgagaact gtgaagcttt acgggctttc
   118981 ttaagacctg gttttttctt cgtatcattg aataagtttg aaaaaccttg atttataaag
   119041 gttttcccgt aaatatattt tattatattt gattaaattt gaaatgtttg tgttctaaaa
   119101 tgtgttctaa tttaaaggca gtatatttcg tattttagat taaattttta ggctcattca
   119161 ttctcaaatc cattctattc agtcaataaa aattttaaaa agactttata aacaaagatg
   119221 ttcaagcgag catcttattt ttttgtgctt aatttgaaag gagaacattt catgtataaa
   119281 aaacaaaaaa agaaattatg tgtattaact attttgagtt tggctgttca agcaattgtt
   119341 ggagcaattg ctcctacgat tacttttgct gatgaaatta cccatccaca aacggtaacc
   119401 gtagaactag atttagcaca tcaatatgct gttgaaggaa cttttagtga tggtcgtcca
   119461 atgtcagaag tcactgttcc gcattatgca gtgtacaacg gctttaaaca agatattttc
   119521 tgtattgaac caggagtccc gatttacaat gagttcactc ctggctatga gaaaaacccg
   119581 ttaccagata tgtccgataa agccaaatta gtttccgttt tatggaaaaa agtaggtaca
   119641 gatgcagata ctcatattgt ggcacagaag atgatctggc aagaagttaa tgggtatacc
   119701 cttcactcaa taaaacgatc agatggtagt gccgtaaata tcgcagccat tgaggcaaaa
   119761 ataaatcaag ccattgacga ttatcagaag aaaccaacct tccataatag tacggctaaa
   119821 acagtattag ggcaatcgac tactgtgacg gatacgaata atctgaattt gtcagagttc
   119881 gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg tgaatggtaa tcagttgata
   119941 atcaccccaa atgccaattc aaaagaaagt ggtgtgctga cgcttaagaa atctgctggt
   120001 accggaacac ctgtcgccta taaaaaggct ggccaacaga ctttaatggc cggggcgatt
   120061 gataaaccta atacctacac aatcaaaatt gatgtggaaa cggagggttc tttaaagatc
   120121 aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa cggttttcca tttagacttt
   120181 ggaaaaactt tacctgcaaa agacgtgact actgacaaag aaggcattgc tacattggat
   120241 gagattcctc atggtacaaa agtaaccatt accgaaaaat cagtaccggc gccttatacg
   120301 attgatacca cccccatgac taccaccatt aaagcaggcg aaaccattta cgtgacttca
   120361 aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa gcggagttga aacagggagt
   120421 gatctttgga atgacaatta ttccttagct ggtaatacgt ttgccattcg caaagacagt
   120481 ccaaccggtg aaatcgttca agaaatgacc acggatgaaa acggtcatgc ggaaacacca
   120541 aaagagattg ctaatgcgtt ggaattggga acctattatg tgaccgaaac taaagctagt
   120601 catgggttcg tgaatacgtt caaacctgta aaagtcgaat tgaagtatgc caatcaaacc
   120661 gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag aagtcactgg cgaaaccact
   120721 ttgacgaaag aagacaaaga tactggggat aaagcacaag gtaaggcagt ctttgagggt
   120781 gctgaataca ccttgtttac tgctaaggat ggaaaagctg ttaaatggag tgaggctttt
   120841 aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa cggtcacttt gactttagac
   120901 gaaaagaacc aagttgccgt taaacattta gctatcaacg agtattattg ccaagaaaca
   120961 aaagcgcccg aaggatatag ccttgatgaa acaaagtatc ctgtatccat caaaaaggtg
   121021 gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta cggcaaaaga acaagtgatt
   121081 cgctttggct ttgatttctt taaatttgct ggatcagctg cgggcactac cgaaactggc
   121141 ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga ccaatgaaat cacaggtgcc
   121201 gaagatgaag cgaccacagc ttataacgag caattagggt ttgatggtta tggcaagttt
   121261 gaaaatcttc cttatgggga ttatttactt gaagaagtag aagccccaga aggttttcaa
   121321 aagattacgc cattagaaat ccgttctact tttaaggaaa acaaagaaga ctttgtgaag
   121381 agtgagtatg tctttaccat taccgaacaa gaccaaaaac aaccaattaa aacggtgacc
   121441 gttccttacg agaagctgac gaacaaagca ttttctgtta gtttgaaccg tttaatgctc
   121501 tatgatttgc ctgaggaaga agatagttta acttctcttg cgacttggaa agacggaaac
   121561 aaagaattaa cttctctgga ttctaccgag ctagttgata aattgagtta caatctacat
   121621 gaaatcaaag aagactggta tgtggtagcg caagccattg atgtggatgc gacaaaagct
   121681 gcccaagaaa aagatgaaaa agccaaacca gtggtgattg cagaaacaag cgcaacgttg
   121741 gcgaacaaag agaaaacagg aacttggaaa attcagcata aattaaccgc cgaacaagtt
   121801 ttaaataaaa ctattgtctt attcaactat gtgtatgaaa ataaggaagc ttttgaagca
   121861 ggcgataagc cagtagcgaa ggatgttagc ttgaataacc aagcccaaac tgtcagttgt
   121921 acagtggaac accatgtttc tatccaaaca aaggcccacc tagaaaacgg ttctcagacc
   121981 tttactcatg gtgatgtggt ggatatgttt gatgatgtgt cgattactca tgatgtactg
   122041 gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt tattaccgga tggtacaaac
   122101 aaagaaattt ggaaatctgg caagattgat tatgaagtaa atgataaaga attcaccaaa
   122161 actgtgcttg cgaaaaaagt agataccgga aaatatccag aaggaaccaa gtttactttt
   122221 gcggaaatca attacgataa agatgggaat atcaatggaa aacacaatga agatttgaaa
   122281 gaaaaatctc aaaccttaac accaaaagaa gttccaacca tactaagtac gccgaaacaa
   122341 ccggaaacac caactgttcc aagtggctct caagaatcta gtcccacagt gaagaccttc
   122401 cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca ttggttttac tttgattttt
   122461 gcgacggcgg gctattattt ctggaatcgc cggaactaag gtgatgagat gatacaagta
   122521 aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag tagtcgcgct atttttgtat
   122581 ccaaaactaa caatgaaaag aggaaaagaa gatggaattg aaatttgtcg tgccagatat
   122641 ggctgaaacc tttggaaagt taagttatgc cggtgaagga gaaattataa cagaaggata
   122701 tggacggaat actacggtga ttggtcgcag ttatcatttg tattccagta agcaacgggc
   122761 cgatgatatt gaggtggtag tagctgcgga agccggtgaa aaggattttg atcaagacca
   122821 accgctaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg agaatcgtgg
   122881 gtttactgat tacgtgttgt atgttgatga tttagtgaaa gcataggagg aaaagaagat
   122941 gagattaaca gaaggtattg tcgtagattc aggtttaaca tttgggaagt tgcgtttttc
   123001 cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acaattggta atgaggtaaa
   123061 agaacgaacc tataatttaa aatcctctgc acaagggcga atgattcaag ttagtatccc
   123121 agctaatgta cccttacgcg agtttgctta tgatgcagag gtagagttgg tcaatccaat
   123181 cgtggatacc gttgccaatt atgtttttcg agaaggaact accgttaatt ggttcattaa
   123241 ggcggatgat ttagtcttga agcggcagcc gaatcaagga aatcctacga accaaaatga
   123301 aagaaagaaa taggtgaaga ttatggaaat taatgttgaa catattttag attgtctcga
   123361 tcaatatgga aaaggcgagc tgactgagga acaactcgtt aaagcattaa cctctgatga
   123421 aaaaatgttt ctgattatac atcaaggttt acttggagaa aatagcgaca gtgaagaaga
   123481 ctctgatgta ctagactggt taggagaaga agagtctttc tttatagttg tcgaagtaaa
   123541 tgaaaactta tgtcggcagg cagaatccat tttggaagaa attggtgtgg agatgccgga
   123601 tgctattgaa ggctttttaa atcaattggt tgaaacgaaa caactcccct cctcgtagca
   123661 gtaaatgact agcataactt tttgaaattg cctaatgaaa tcctattggg ctttttcgat
   123721 tggaggtgga aaccatcaaa atgtacaaag gacatcgcat acgcgcagga gatcagcact
   123781 tggtttatca ctttgttctt ggctggctac tcgctctgtt catcggttgg atgagcgtct
   123841 tttattttca agagtttaga caatttgata tttctaagct atcactttct actattgaaa
   123901 tcgtttggtc tataaaagat ttagtatgtc tgcttggaag tctcgctttt tcaggagcta
   123961 tgatattgct ttatattcac ttttttcttg atcattggcg aagcttgtgg catcgacaaa
   124021 agctagctcg gatgattcta gagaaccatt ggtatgaagt gaaacaaact caaagtgaag
   124081 gctttttcaa agatttgaat agtagccgaa ccagagagac tatcagttac ttccccaaaa
   124141 tctgttatcg aatgaaagat ggattactgt ctattcgcgt tcaaatttca cttgggaaat
   124201 accaagatca gcttttaaaa ttggaaaaga agttagaaag cggactgtat tgtgagttag
   124261 tagaaaagga actcaaagac tcctatgtgg agtatacttt actgtatgat atgatcgcca
   124321 atcgaattgg gatagacgaa gtagtggcag aaaatgggac tctgcgattg atgaaaaatc
   124381 aagtatgggc ttatgattct ttaccccata tgttaatcgc tggtggcacg ggtggaggga
   124441 agacctattt cctcctcacc attatcgaag cactattgaa gtcagatgca gaattgttta
   124501 tcctcgatcc caaaaatgca gatttagctg atttaggtac ggtgatgcct catgtttatt
   124561 cacaaaagga agaaatttct gcttgtgtgg aagatttcta tgaacgtatg atggctcgta
   124621 gcaaggcaat gaaagaaatg tctaactaca aaacaggaga gaattatgcc tatcttggac
   124681 ttccacccaa ctttttaatc tttgatgaat acgtggctta tatggagatg ttaacgacga
   124741 aagaaagtgc ggtgattttg aataagctca aacaaatcgt gatgttgggt cgtcaatctg
   124801 gtttctttct gattttggct tgccaaaggc cggatgcgaa atatttagga gacggaatcc
   124861 gcgatcaatt caactttcgc gtggctttgg gtcgtatgag tgaactcgga tattccatga
   124921 tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat caaaggtcga ggttatgtgg
   124981 atacaggtgg cagtgtgatt agtgagtttt atacgccact tgtaccaaaa gggtatgatt
   125041 tcttagattc aattagtaaa ttagaaaaga tgaatgattg agtgatcttc aatactgact
   125101 ttatacttca agtaacgtat aatactttta tatagtagga agaaagggga taattaatat
   125161 ggaaagtaat gattcttatt tagagtatgc aaaagcaaat aaggataagt ttatttctta
   125221 tattatcaaa gggaaatccc ccgaagttgg acgagacgca gtttttatgg cagggagtcc
   125281 tggggctgga aaatcagagg ttgccattgg attagctgag aattatgata accatgtgat
   125341 tattgatgcg gattactttc gcacccagtt tcctgattat aatggaaaaa actctagtct
   125401 ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt agatatgtct tagatcatgg
   125461 ctattctttt attctggatg caacttttgc aatattaagt gctgaaaaaa atatctcgcg
   125521 ggcgttgaaa aaacattttc gagtgacgat tttctatgtt tatcaagacc ctaaaatcgc
   125581 ttggaaattt acacaagaac gtgaaattgc agagggacgt catgtgccga aaaaggcatt
   125641 tattaacgct tttttcaaat caagagagaa cattgcaaaa gtaaagagta aacatccaga
   125701 tgtattgctt catatcataa taaaagatta tacgaataat atttccgaag ttcattatgc
   125761 tacggataat ctagaattat ttttaccact agggtatagt aggaaagatt tggaggttca
   125821 attacatgac tgagaaagaa caagtaacga aaattgtaaa gaaatacaat aagagcattg
   125881 cggatttatc ggaaaatgct actgcaaaag agttcaaaac ggtgattaaa tatgtagccg
   125941 atcaggccaa tgaaaaacaa cggaaattag ttggattaaa taaaaaatag taggacaaat
   126001 taataatgta tgagccaaga gcaaaatgtt cttggctttt ttctttgcaa tgaatgaggt
   126061 aatgtatgag atttttagat ttattcgccg gtattggtgg ctttcgttta ggtatggaac
   126121 aggcgagcca tcattgtatc ggtttttgtg aaattgataa atttgctaga cgtagttata
   126181 aagcaattca tgatacaagt aaggaggtgg aaatgcatga catcacaagt gtatcagatg
   126241 agtttattca atccctcgga ccagtggaca tcctttgcgg cggatttccg tgccaagctt
   126301 tttcaattgc gggaaagcgg caaagatttt ccgatactcg aggtacttta ttctttgaaa
   126361 tcgctcggtt caccactctt ctccgaccta agcttttatt ccttgagaac gtccgaggat
   126421 tgctcaatca cgaaggaggg gctacgttcg agacgatcct ccgaacgctg gatggattgg
   126481 ggtatgacgt ggagtggtag gtgcttaact caaaggccta cattccccaa agccgggagc
   126541 ggatattcct tatcggacat tctcgagacg catgtaccga acaagtattt cctatcattg
   126601 gaccgtcttc aacatctgat caaaacatca gaaatttggt aaatatcaat ccttccaatc
   126661 gaggaatggg tggacaagtc tatggttcag atggcgtagc gccaacctta acaggtgatg
   126721 aaggaatcaa aatcgcactg ccagcaaggg atggaatctc tgtagcagga ctattaccgg
   126781 gaaagtttga acaaggtaat cgagtttatg aagttactgg aaccgccccc accttgtcaa
   126841 cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga aacagaatat caagaggtga
   126901 agccagaaga cagtgtgaat ctggcttttc ctaattccac aagtcgccga ggtcgtctgg
   126961 gaaaacagag tgttcatacc ttactaacag gagaccaaca agcgatcgtc acggatcagt
   127021 atcaaattcg gaagctaaca cctagagagt gttggcgact tcagggcttt cccgattggg
   127081 cttttgatcg agattctcaa gtcaattcag atagtcagtt gtataagcaa gccggaaact
   127141 ctgtaacagt tccggtcatt tttgatattg ccagaagatt aaaagagttg gatgtacatg
   127201 gtttatgatg agttgattgg agaaatttat tgggtgattg gaaagattca gtcagaccca
   127261 gaattagaag aacaattgcg acggttaaaa tttgatattc gcaagaatgg tgtcaaagtc
   127321 gctggcgatc catatttaat gaatgaggag acggatgctc gaattgaaat aaatcaagta
   127381 attgcagaat ttgagcggat tgcggaccaa gcaaaagaac cagatattcg tcaatacttg
   127441 ttagaaatga aagcagagtt ggaagtaaat ggtattacag atgagtaacc taaaccaaca
   127501 caactgactg ttaggcgctg accgcggagg attcgcgaag cagaaatcct ccgtggtgct
   127561 gtgcctgttc atggacggcg ttagccgacc atgatgtctc acccccgtat ctaacagggg
   127621 ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa tgcttgttgt atcaaagata
   127681 gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt aacaccttga atttggaggt
   127741 gagaacttgg cacaacggaa tttagattat cggctattaa aagaccgacg caacgaatac
   127801 ggcgtttcac aaaataaatt ggctacggct tgtggactta gtcggccgta cttaaatcag
   127861 atagaaaatg gtggcgtaac cgcatctata aaaaccatga ggaaaatttt tgaccaactg
   127921 gaaagcttta atcccgattt gcctttgacg ttactgtttg actatgtaag gattcgcttt
   127981 cccacaacgg atgcacgaaa aattattcaa gaaattctcc atttgaaatt tgagtatatg
   128041 ctccatgaag attatgcctt ttactcctat caagaacagt atgtcatggg tgatattgtg
   128101 gtgatgttgt ctcatgaaga agataaaggt gtgcttttag aattaaaggg gcgaggttgc
   128161 cgacaatttg aaactttttt actcgctcaa aagcgtagct ggtacgactt tttcgaggat
   128221 tgtctaaagg ccggtggcgt gatgaaacgc ttggacttgg caatcaatga tcgagtgggg
   128281 ctattggata tacctgagct aacgaaaaaa tgtcagaagg aagaatgtat ctccttgttt
   128341 cgtaccttta aaagttatcg ttccggggaa cttttaaagg ctgatgaaaa ggacggcatg
   128401 ggcaatacct tatatatcgg cagtctcaag agtgaggttt atttctgttt gtatgaaaaa
   128461 gactatgaac aatatatcaa gttagggatt ccattagacc aaactgagac gaaaaatcgt
   128521 tttgagattc gactgaaaaa tgaccgtgct tttcatgcga ttcaagattt gttaaaaggt
   128581 cgtagcattg agagcaccac gttttccatt atcaatcgtt acttgcgatt tgcggataaa
   128641 gtagaaggta aaaggcgaac caactggccc ttgaatgaac aatgggggcg ttttattgga
   128701 cggaatcgga aagagattca attaacttcc gagccaaaac cgtataccat tgaacgaacc
   128761 ttgaattggc taggccgaca agtcgcccct acgtggaaaa tggctaagga gttggatcga
   128821 ttgaatcgga caacctatat ccaggatatg gtacagaatg cacgcttatc agaccgacat
   128881 aaaaagattt tggagcaaca aagtatggca attgaaaatt tgattatatg aaaagaggaa
   128941 tcgtcatggg aattgtaaaa gatatttttt tggtatttgg tggcagtatg cttggtgtta
   129001 ctgtgatgtg cttgatgaat gcaagtgcag cagcggatcg agcaatggaa aagaaaggaa
   129061 agtgacaaga tgaatttcgg acaaaattt
//
LOCUS       DAFEML010000002       107449 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFEML010000002
VERSION     DAFEML010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 107449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.002"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..187
                     /locus_tag="LP468_000120"
     CDS             <1..187
                     /locus_tag="LP468_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBL2079689.1"
                     /translation="GLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDK
                     KLFQARVTSLEQLLSTV"
     gene            complement(905..4054)
                     /locus_tag="LP468_000121"
     CDS             complement(905..4054)
                     /locus_tag="LP468_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBL2079690.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(4068..5312)
                     /locus_tag="LP468_000122"
     CDS             complement(4068..5312)
                     /locus_tag="LP468_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL2079691.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5305..6897)
                     /locus_tag="LP468_000123"
     CDS             complement(5305..6897)
                     /locus_tag="LP468_000123"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL2079692.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7406..8131)
                     /locus_tag="LP468_000124"
     CDS             complement(7406..8131)
                     /locus_tag="LP468_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079693.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8285..8611)
                     /locus_tag="LP468_000125"
     CDS             complement(8285..8611)
                     /locus_tag="LP468_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079694.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8648..9013)
                     /locus_tag="LP468_000126"
     CDS             complement(8648..9013)
                     /locus_tag="LP468_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL2079695.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(9050..9265)
                     /locus_tag="LP468_000127"
     CDS             complement(9050..9265)
                     /locus_tag="LP468_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2079696.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9394..9729
                     /locus_tag="LP468_000128"
     CDS             9394..9729
                     /locus_tag="LP468_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2079697.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9805..11802)
                     /locus_tag="LP468_000129"
     CDS             complement(9805..11802)
                     /locus_tag="LP468_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079698.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11900..12175)
                     /locus_tag="LP468_000130"
     CDS             complement(11900..12175)
                     /locus_tag="LP468_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2079699.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12407..13141
                     /locus_tag="LP468_000131"
     CDS             12407..13141
                     /locus_tag="LP468_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2079700.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            13180..14322
                     /locus_tag="LP468_000132"
     CDS             13180..14322
                     /locus_tag="LP468_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2079701.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14417..15808)
                     /gene="sufB"
                     /locus_tag="LP468_000133"
     CDS             complement(14417..15808)
                     /gene="sufB"
                     /locus_tag="LP468_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL2079702.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15813..16283)
                     /locus_tag="LP468_000134"
     CDS             complement(15813..16283)
                     /locus_tag="LP468_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL2079703.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16270..17505)
                     /locus_tag="LP468_000135"
     CDS             complement(16270..17505)
                     /locus_tag="LP468_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2079704.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17502..18788)
                     /gene="sufD"
                     /locus_tag="LP468_000136"
     CDS             complement(17502..18788)
                     /gene="sufD"
                     /locus_tag="LP468_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL2079705.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18801..19574)
                     /gene="sufC"
                     /locus_tag="LP468_000137"
     CDS             complement(18801..19574)
                     /gene="sufC"
                     /locus_tag="LP468_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL2079706.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19771..20619)
                     /locus_tag="LP468_000138"
     CDS             complement(19771..20619)
                     /locus_tag="LP468_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2079707.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20643..21329)
                     /locus_tag="LP468_000139"
     CDS             complement(20643..21329)
                     /locus_tag="LP468_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079708.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21322..22356)
                     /locus_tag="LP468_000140"
     CDS             complement(21322..22356)
                     /locus_tag="LP468_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2079709.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(22419..22675)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(22751..23089)
                     /locus_tag="LP468_000141"
     CDS             complement(22751..23089)
                     /locus_tag="LP468_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL2079710.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(23091..23447)
                     /locus_tag="LP468_000142"
     CDS             complement(23091..23447)
                     /locus_tag="LP468_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL2079711.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23453..24640)
                     /locus_tag="LP468_000143"
     CDS             complement(23453..24640)
                     /locus_tag="LP468_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2079712.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24831..25676)
                     /locus_tag="LP468_000144"
     CDS             complement(24831..25676)
                     /locus_tag="LP468_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2079713.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25910..26875
                     /locus_tag="LP468_000145"
     CDS             25910..26875
                     /locus_tag="LP468_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL2079714.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            27252..28295
                     /locus_tag="LP468_000146"
     CDS             27252..28295
                     /locus_tag="LP468_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL2079715.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(28357..28821)
                     /locus_tag="LP468_000147"
     CDS             complement(28357..28821)
                     /locus_tag="LP468_000147"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL2079716.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            29067..30014
                     /locus_tag="LP468_000148"
     CDS             29067..30014
                     /locus_tag="LP468_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2079717.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(30225..32297)
                     /locus_tag="LP468_000149"
     CDS             complement(30225..32297)
                     /locus_tag="LP468_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2079718.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(32230..32607)
                     /locus_tag="LP468_000150"
     CDS             complement(32230..32607)
                     /locus_tag="LP468_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL2079719.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(32736..33314)
                     /locus_tag="LP468_000151"
     CDS             complement(32736..33314)
                     /locus_tag="LP468_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2079720.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            33446..34738
                     /locus_tag="LP468_000152"
     CDS             33446..34738
                     /locus_tag="LP468_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2079721.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34798..35916)
                     /locus_tag="LP468_000153"
     CDS             complement(34798..35916)
                     /locus_tag="LP468_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL2079722.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35930..37351)
                     /gene="arcD"
                     /locus_tag="LP468_000154"
     CDS             complement(35930..37351)
                     /gene="arcD"
                     /locus_tag="LP468_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL2079723.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(37597..38718)
                     /gene="mnmA"
                     /locus_tag="LP468_000155"
     CDS             complement(37597..38718)
                     /gene="mnmA"
                     /locus_tag="LP468_000155"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL2079724.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            39122..39721
                     /locus_tag="LP468_000156"
     CDS             39122..39721
                     /locus_tag="LP468_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2079725.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39859..41145)
                     /gene="efmA"
                     /locus_tag="LP468_000157"
     CDS             complement(39859..41145)
                     /gene="efmA"
                     /locus_tag="LP468_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL2079726.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(41416..41760)
                     /locus_tag="LP468_000158"
     CDS             complement(41416..41760)
                     /locus_tag="LP468_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL2079727.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41897..43042)
                     /locus_tag="LP468_000159"
     CDS             complement(41897..43042)
                     /locus_tag="LP468_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2079728.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(43222..44196)
                     /locus_tag="LP468_000160"
     CDS             complement(43222..44196)
                     /locus_tag="LP468_000160"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2079729.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(44276..45151)
                     /locus_tag="LP468_000161"
     CDS             complement(44276..45151)
                     /locus_tag="LP468_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL2079730.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            45281..47188
                     /locus_tag="LP468_000162"
     CDS             45281..47188
                     /locus_tag="LP468_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL2079731.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(47729..51007)
                     /locus_tag="LP468_000163"
     CDS             complement(47729..51007)
                     /locus_tag="LP468_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL2079732.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(51278..51823)
                     /locus_tag="LP468_000164"
     CDS             complement(51278..51823)
                     /locus_tag="LP468_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2079733.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(51835..52527)
                     /locus_tag="LP468_000165"
     CDS             complement(51835..52527)
                     /locus_tag="LP468_000165"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL2079734.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(52546..52830)
                     /locus_tag="LP468_000166"
     CDS             complement(52546..52830)
                     /locus_tag="LP468_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079735.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(52843..53406)
                     /locus_tag="LP468_000167"
     CDS             complement(52843..53406)
                     /locus_tag="LP468_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2079736.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            53634..54296
                     /locus_tag="LP468_000168"
     CDS             53634..54296
                     /locus_tag="LP468_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL2079737.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            54420..55616
                     /locus_tag="LP468_000169"
     CDS             54420..55616
                     /locus_tag="LP468_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL2079738.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(55717..57093)
                     /locus_tag="LP468_000170"
     CDS             complement(55717..57093)
                     /locus_tag="LP468_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2079739.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(57130..57996)
                     /locus_tag="LP468_000171"
     CDS             complement(57130..57996)
                     /locus_tag="LP468_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL2079740.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(58085..59110)
                     /locus_tag="LP468_000172"
     CDS             complement(58085..59110)
                     /locus_tag="LP468_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2079741.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(59128..59802)
                     /locus_tag="LP468_000173"
     CDS             complement(59128..59802)
                     /locus_tag="LP468_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2079742.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(59986..60879)
                     /locus_tag="LP468_000174"
     CDS             complement(59986..60879)
                     /locus_tag="LP468_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2079743.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(60953..62650)
                     /locus_tag="LP468_000175"
     CDS             complement(60953..62650)
                     /locus_tag="LP468_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2079744.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(62643..63956)
                     /locus_tag="LP468_000176"
     CDS             complement(62643..63956)
                     /locus_tag="LP468_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL2079745.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(63956..67474)
                     /locus_tag="LP468_000177"
     CDS             complement(63956..67474)
                     /locus_tag="LP468_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2079746.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(67767..68225)
                     /locus_tag="LP468_000178"
     CDS             complement(67767..68225)
                     /locus_tag="LP468_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2079747.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(68499..69041)
                     /locus_tag="LP468_000179"
     CDS             complement(68499..69041)
                     /locus_tag="LP468_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2079748.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVICINCTNKA"
     gene            complement(69043..69660)
                     /locus_tag="LP468_000180"
     CDS             complement(69043..69660)
                     /locus_tag="LP468_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL2079749.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(69657..70511)
                     /locus_tag="LP468_000181"
     CDS             complement(69657..70511)
                     /locus_tag="LP468_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2079750.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(70508..71419)
                     /locus_tag="LP468_000182"
     CDS             complement(70508..71419)
                     /locus_tag="LP468_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2079751.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(71460..72794)
                     /locus_tag="LP468_000183"
     CDS             complement(71460..72794)
                     /locus_tag="LP468_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2079752.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            73002..73832
                     /locus_tag="LP468_000184"
     CDS             73002..73832
                     /locus_tag="LP468_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL2079753.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(74076..74394)
                     /locus_tag="LP468_000185"
                     /pseudo
     CDS             complement(74076..74394)
                     /locus_tag="LP468_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(74516..74710)
                     /locus_tag="LP468_000186"
     CDS             complement(74516..74710)
                     /locus_tag="LP468_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079754.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(75215..75400)
                     /locus_tag="LP468_000187"
     CDS             complement(75215..75400)
                     /locus_tag="LP468_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079755.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(76250..76591)
                     /locus_tag="LP468_000188"
     CDS             complement(76250..76591)
                     /locus_tag="LP468_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2079756.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(76591..76821)
                     /locus_tag="LP468_000189"
     CDS             complement(76591..76821)
                     /locus_tag="LP468_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2079757.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            77108..77446
                     /locus_tag="LP468_000190"
     CDS             77108..77446
                     /locus_tag="LP468_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079758.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(77651..77890)
                     /locus_tag="LP468_000191"
     CDS             complement(77651..77890)
                     /locus_tag="LP468_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2079759.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(77866..78213)
                     /locus_tag="LP468_000192"
     CDS             complement(77866..78213)
                     /locus_tag="LP468_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2079760.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78945..79526)
                     /locus_tag="LP468_000193"
     CDS             complement(78945..79526)
                     /locus_tag="LP468_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2079761.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(79709..80335)
                     /locus_tag="LP468_000194"
     CDS             complement(79709..80335)
                     /locus_tag="LP468_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2079762.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(80357..81688)
                     /locus_tag="LP468_000195"
     CDS             complement(80357..81688)
                     /locus_tag="LP468_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL2079763.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(81843..82244)
                     /locus_tag="LP468_000196"
     CDS             complement(81843..82244)
                     /locus_tag="LP468_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2079764.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(82330..82536)
                     /locus_tag="LP468_000197"
     CDS             complement(82330..82536)
                     /locus_tag="LP468_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079765.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(82631..84133)
                     /locus_tag="LP468_000198"
     CDS             complement(82631..84133)
                     /locus_tag="LP468_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL2079766.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(84151..84606)
                     /gene="argR"
                     /locus_tag="LP468_000199"
     CDS             complement(84151..84606)
                     /gene="argR"
                     /locus_tag="LP468_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2079767.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(84704..85321)
                     /locus_tag="LP468_000200"
     CDS             complement(84704..85321)
                     /locus_tag="LP468_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL2079768.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            85542..86915
                     /locus_tag="LP468_000201"
     CDS             85542..86915
                     /locus_tag="LP468_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2079769.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86990..88102
                     /locus_tag="LP468_000202"
     CDS             86990..88102
                     /locus_tag="LP468_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL2079770.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(88174..89811)
                     /locus_tag="LP468_000203"
     CDS             complement(88174..89811)
                     /locus_tag="LP468_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL2079771.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89979..90587)
                     /locus_tag="LP468_000204"
     CDS             complement(89979..90587)
                     /locus_tag="LP468_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2079772.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90972..92123)
                     /gene="queG"
                     /locus_tag="LP468_000205"
     CDS             complement(90972..92123)
                     /gene="queG"
                     /locus_tag="LP468_000205"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL2079773.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(92142..92894)
                     /locus_tag="LP468_000206"
     CDS             complement(92142..92894)
                     /locus_tag="LP468_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079774.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(93035..93985)
                     /locus_tag="LP468_000207"
     CDS             complement(93035..93985)
                     /locus_tag="LP468_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2079775.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(93986..94825)
                     /locus_tag="LP468_000208"
     CDS             complement(93986..94825)
                     /locus_tag="LP468_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2079776.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(94822..95568)
                     /locus_tag="LP468_000209"
     CDS             complement(94822..95568)
                     /locus_tag="LP468_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2079777.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            95806..97176
                     /locus_tag="LP468_000210"
     CDS             95806..97176
                     /locus_tag="LP468_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2079778.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(97231..98127)
                     /locus_tag="LP468_000211"
     CDS             complement(97231..98127)
                     /locus_tag="LP468_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2079779.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(98241..98411)
                     /locus_tag="LP468_000212"
     CDS             complement(98241..98411)
                     /locus_tag="LP468_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079780.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(98408..99085)
                     /locus_tag="LP468_000213"
     CDS             complement(98408..99085)
                     /locus_tag="LP468_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2079781.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(99176..100081)
                     /locus_tag="LP468_000214"
     CDS             complement(99176..100081)
                     /locus_tag="LP468_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2079782.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            100256..101710
                     /locus_tag="LP468_000215"
     CDS             100256..101710
                     /locus_tag="LP468_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2079783.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            101726..102757
                     /locus_tag="LP468_000216"
     CDS             101726..102757
                     /locus_tag="LP468_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2079784.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            102764..103951
                     /locus_tag="LP468_000217"
     CDS             102764..103951
                     /locus_tag="LP468_000217"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL2079785.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            104107..105489
                     /locus_tag="LP468_000218"
     CDS             104107..105489
                     /locus_tag="LP468_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL2079786.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            105461..105847
                     /locus_tag="LP468_000219"
     CDS             105461..105847
                     /locus_tag="LP468_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079787.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(106047..106715)
                     /locus_tag="LP468_000220"
     CDS             complement(106047..106715)
                     /locus_tag="LP468_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL2079788.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(106904..>107449)
                     /locus_tag="LP468_000221"
     CDS             complement(106904..>107449)
                     /locus_tag="LP468_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBL2079789.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSLVQFRKTTVTVV"
BASE COUNT        30785 a        22396 c        18934 g        35334 t
ORIGIN      
        1 aggcttggaa aaagtcgcga cgcatacgat gctagtgttt gctgcaatga atttaaagaa
       61 attagccacc tggctatgga aaggcaagga gcctttattt ttttgttcaa aaattcgaaa
      121 cgaagtagat aaaaagctgt tccaagctcg agttacgagt ttggaacagc ttttgtctac
      181 agtctgagga ctaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt
      241 ttattggatt attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac
      301 tgagtcatat agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt
      361 taaaatcaat acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat
      421 atatacagtc ccataggtaa agtgccacag gactgtatat ttttttattt gagattacct
      481 gaaatgattc catttacttt ttatctcatt ttttcctact agttagtatc aaatactctc
      541 ctattttctc aataaactat tttgggttac atggtatctg aaacagctaa aaccttgtca
      601 ttacagcaaa aaatcacttt atctccgttt catttcagat acatttcact taagcggatt
      661 ccaaaaaaac aaaagaaaaa ggaaccccta gttagcctat gctttttatt ggttcctctc
      721 aaaacacggt catataacaa cggggtgggg taaatgaatg aaaaaggtgg aggaaacatt
      781 attcaatagc tgtcttaaat acttcgttat aaaatgtgaa caaataaaag acatctatcc
      841 ctattttcta cacttccact ttactaccat ctttgaatcg tacaattttc ttaactcttc
      901 tcgtttacct caattcattt tcaagtggaa tcagctcatc atctaacatt ttacgccatg
      961 ctcgcttcat ttcttgtggg tatttaaatg gcttcgcttc tggatggttg gctttatatc
     1021 cttcgtaatc cttactgttg ataattgctt tcatattagg aattggatct tcacctggca
     1081 tatattgcag attagaagca tgtaattctt tctcagaaac aaaccactca ttggaaaaga
     1141 catgaatcaa atcatcactc gcttgtgtaa aatagcgacg tttaatgaca aagatatctt
     1201 cattactatc taaagtcccc acatcaaacg catttaaaat ttgtcggtaa acttctttga
     1261 ctccttctgt tttattcaat ttagccaaag ctttttcaat ttcttctcgt gcatctgaac
     1321 tattcgccgc ataagttcct agtaattgat caatataagt agaatcaata tcatacaact
     1381 tcgtggtatt ttcactataa aattcgatcg tggaaaaatc ttctccctct ttttctggtt
     1441 cttcctctat taatgaaccc ttcacggtct cgtacacgcc aatttgttct tccaaaagtt
     1501 gaatttgatt gttcaaggtt gaagatttca ccatgtcatc attgtaatcg tcataagtca
     1561 ctaacgattc ataagcacga ttcaattctt ggaatgcttt gacgtactcg atacggattt
     1621 caagtggcgt atgttcatca atggattcca tggatgaaac ctcttttaac ttaccatatg
     1681 cttgcttgaa tctttttttg gattcctgat aacttggata aatcaaaccc gattcttctt
     1741 ttgcttctga atacagtttt gtcgcatcct cgacattctt ctccattgtg gctggctttc
     1801 ggaaagtaac aattagtcct tttgtttttt ctggatacgt acggttcgta cgtgaaaaag
     1861 cttggatcaa tcctgcatac tctagattac gatccacaaa tagggtttga atcgtaggtg
     1921 cgtcaaaacc tgtcaataga cgatccacta cgatcactaa atcaatttgt ttcccaaatt
     1981 gtttgaattc cgctcttttt cgtgccaaac gattattgat gtctccgtta taacgctcaa
     2041 tgtctgctaa tgaccaggaa gtattataat actgattata ttcctcaata attttttgca
     2101 tttcttcttg ttggacactt gaatctcggc tgttttcttc taatgaatag gtaatagcga
     2161 ttcgtggaaa atcaggatcc tccatcgttc ttccttcacg aatgggctga ttaggaaact
     2221 cttttgttaa ccagtcaggt tctttcgtca tttctttgat cgctcgataa tactttttgg
     2281 ccatgtcaat ggaactcgtg gttaagatcg cagacttcgt tggacggcca tttcgaaaat
     2341 caaattttgt ataggcattg tctggacgga acattttatg aatgactttt tggatatgtt
     2401 catctgcttc aaaaacagta gggtccaaat aactttcttt tttgacaggc tccatttgat
     2461 caatcatacg attgatctgt tccggtgaat actctgcata tgtttctact tcttttaatt
     2521 tccgatagat tttattctct aatgaagtcg gctccacggt gttttcatgc tctacttgaa
     2581 atcctaaaac cgagccatct tctaatgcat tcttgatggt ataggtatgc aagacctctc
     2641 catactgatc atgggtcgta cgtgccaatt gccctttggc ttgtttccga ttctcaggga
     2701 aaatcggtgt acctgtaaag ccaaaccaag tggatttcgg aaacattttt ttgatttctt
     2761 ccatattttc agcacttaac gctcgatgac actcatctac tacaaacacg atatgttgcc
     2821 ccattaattt ttggaagcga ttggttcctt ttttctcttc ttgttttttt gcatatttca
     2881 acgccgcatc tagcttttga cgggttgtaa taatcacaac atttgcattg gcatctgcca
     2941 acagagtttc acttaactct ttggcacttc ctgttcccac gatcaagcta ttcgctttgg
     3001 cgttcccgga agaaatccca gtattaaatt ccgaagcaaa tttcgtaaac tctgtggtgg
     3061 tttgattatc taaatctttg cggtccacta acatgatcgt ccgatcgatc cccgattttc
     3121 gtgctaaaag cttagtagat acaaaactag tcaacgtttt tcctgaacca gtcgcatgcc
     3181 acacatatcc tgattgatgt ttatttgcag caataaacaa ggcttgaatc gcatgtactt
     3241 gataaggatg taacaccatg aggattttat tgtcttgatc ttcactgaca atcgtataat
     3301 ccgcaatcaa gcgatgagca tccgggatat ttagcacttg tttgcaaaac tcatataagt
     3361 tttctacctt tttattatct ttcgttcgcc aactaaataa aaacttagga tgcaaatcct
     3421 ttggtaaggc atttgcaaaa taccgagtgg tttgttcatt ggaaaccaca aacaactgta
     3481 aggtcgaaaa gatattgttc cgaaacatac cttcttctgc atattttttg atttggttaa
     3541 acgcctgata aaaactatct tttgcggtta cttgtttcag ctcgatttgg acaatcggta
     3601 atccattgat cagtaaggtg acgtcaaaac gtcgatcccg tgcttctatg ttacttccac
     3661 gttttgcaat ttgatggacc acttcatagg tagagattcc tccaccaatg tcttgattag
     3721 aataaagaat gagcgagaca gaacccagtt gcggatcttc ccgttcaatc gtgatccgag
     3781 ccattccatt ttcacctttt aaccatttcg cagcatcaaa gggggttttc gttcgtagta
     3841 acaattctgt tttgatcgtt tcaaattctt tatcggtcaa aggaaaatca ttcagttctg
     3901 cttgattatt tgagatgatt ttttggcgta aattgaccca aagatcttct tctgatttta
     3961 gatcgggacg atacgtccac tgattatgcc cttcccccaa tacacggatc aactgttctt
     4021 cgacttccgc ttcctcacgg tgactaattt tcatttatct tccctcccta aacaaacatc
     4081 ttttgtaaga agcctttttt cgtttccttc agcaaatcta acttacgttg atgaagagcg
     4141 atcgtgtcgt cgagttgttt gaagaaagcg ccgatttttt gttgttcctc tttattccta
     4201 gtaaaaggaa acttgatatt agcgaaattc tcatagaata agtattctcg tacgcttcct
     4261 tcagtgttgc gcttgacctc tttgataaat gttggtgact tgataaactg aagtatgaac
     4321 tcattatcta agtcctcgct cattttcaca actacataaa gagagctaac aatgaccgtc
     4381 ataccaagat tgttaaatgc aattgatcct acgtttactc ttgctggatt ataggcgaat
     4441 tcatttggtt caacgaattt ataatttgtt ttttctaaat catccaacct actaccatca
     4501 aactgttctg tttgagaaat taaacctgct ttattactta ccgaataggc agggaagtct
     4561 aaatctttcg tgttcttttt tccagtcttc ttactaaact ctttgaactt acgctgttcc
     4621 caatcttccg taaatccagg aaaccgaatt tctggcactt ttgctccgtt tttagggaac
     4681 attttttgta agaatccttt tttcgtttcc tttaataaat ctagcttacg ttgttgaaga
     4741 gcgatagtgt cgtccagttg tttgaagaag ttcccaattt tcttttgttc ttctaatatt
     4801 ggaaattgta ctatccattt tttcacttct gacattggta cgagatttgt aattgctgaa
     4861 cctggattag ctcctgtgag ttttctttgc ataaaatctg cacgaataaa ttgaataaaa
     4921 tattctgaat ctgtgatttc tttatttatt ctaagtctaa tcaaagcctg attgaataca
     4981 cccggtttta tttgctttgg tactcttgaa attctcccaa ttgttccagc gccactcatg
     5041 ataaaatcgc ctggttctaa tttaaatttg attaattcat tatatttttt ttcagtaatt
     5101 ttatatcttg tttcgtaatt atcataaata gcattttgtt gttcatagac aacaaaattg
     5161 ctattagata caaagaattc tttctttaag gcactcccaa atggtcccct ccttactcca
     5221 tcttttttat caagtaagca ttcaaactta cgctgttccc aagcttccgt aaatcctggg
     5281 aaacgaattt ctggttgtat atcattactc atgtttgaac acctccagcg caccttgtaa
     5341 ccacgcttca ttttcaggtg ttgtttgcag ggaagagata gcttctaaaa gttctttttc
     5401 tagcacttgc tgttcttgtc gtatcttctt gatgtcattt ccgacatgaa ccatatcaat
     5461 tggttcttct tcttcaaacg tatctacata gcgtggaata tttaagttat agtcattttc
     5521 tttgatttca tcaaagtttg ccaaatgagc gtatttctcg acatcttttc tttcagcata
     5581 ggtttcgagg attttttgaa tgttttcttc cgataattta ttctgatttt ttcctttgac
     5641 aaattctcga ctagcgtcaa tgaataatac gtctcgagtt tggcggttct ttttcaatac
     5701 aatcaccgtc gttggaatcg atgtcccgaa gaacaagttc gcaggcatac cgatcacagc
     5761 ataaatactg ccgtcttcta gtaatttttg acgaatgacc ccttctgcag cgccacggaa
     5821 taaaactccg tgtggcaaga cgatggccat agtccctgtt tccttcaaat gatagaaacc
     5881 atgaagaaga aacgcaaaat ctgctttgga ttttggcgct aattttccat aacgattaaa
     5941 ccgagaatcg tctaagaagg tcgtatctgc tgaccaatta gccgaataag gtgggttcat
     6001 tactactgca tcaaatgtgt aaggttcatc tgttggccaa tccttattca acgtatcccc
     6061 attgcggaga ttcatttctt cggcatctac cccatgtaaa atcaagttca tttttgctag
     6121 attgtatgtc gttgtattta attcttgccc atgatattta acgttatctg ggtgagttaa
     6181 gtagttacgc acatttaaca tcaatgaacc tgaacccatg gttggatcaa aaacactaaa
     6241 gaatcgtcgt tctttttgat ccaacgtcac gatttgtgcc atcatatcag aaaccatatg
     6301 aggcgtgtaa aattctccgg ctttcttccc tgcttctgaa gcaaattgac tgatcagaaa
     6361 ttcataagca tccccgatca cgtccccatc gtgacctaaa acttccacgt cattcaattt
     6421 cttaatgact tcggtaatcg tcacatttcg ttgttgctca tctgttccta gtttttttga
     6481 ttggagatcc acatcatcaa ataacccatt aaattgattg taggtagatg ccaattgcac
     6541 aaaggctttg tttagatcat tcaattggaa cgttgcttgt tttgcttgat ccgctaagac
     6601 gttgaaaaga tactctggcg aaatcgcata ccccaaaata tcaacgattg ttgcaatcag
     6661 atcttctttt gattcttcat ctgaaagtaa ttcgcgatac aacatcgttt gtttgcttac
     6721 cgtatcatat tcctctaagg attcatctgc taaaagaacc acttgttcca acaaacggtc
     6781 ggataaatat ttatagaaaa tcagtcccaa taaataattt ttatattctg acgcatccat
     6841 tttgctacgg agattatctg ccgcactaaa taatttttga tttaattctg cacccaaaaa
     6901 gatacactcc tatctcttat ttaaagttgc tatataccct cttattttag catactccct
     6961 tttagaaaaa gcaaaaaaaa aagaaagaaa cttattcttg ctaataaact acgcgaaagg
     7021 agtctaacgt tgtttgatat aacttagact gatcgttaac ttatttttta tatttctaca
     7081 tagttatctt tagaaccatt tcagatacat atgaaacaat tacatatgat tttttcataa
     7141 aaaaacagta ctgtctagta gtataaaata tacaaatttc ttaaaaattt tttcactaaa
     7201 atcactacct gaaacagtct aaaacactta tatatcaacg tttaatgaaa ctatctccgt
     7261 ttcatttcag atacaaataa atatagtcgg gctccaaatc cgaaaaaaaa tacccccagt
     7321 agcttatcct aagctactgg agatgtataa gtacggtcat ataacaacgg ggtagggtaa
     7381 ataaatgaaa aagatggaag aatcattatt caataacttt tttaaatact tcgttgtaat
     7441 cagttacctg tccgttctta aataccacag aataatcttt tttcccattt tcaagtaacc
     7501 gaagtggaat atctttacca actttctctg tcactgcatt actgatacct gttagattag
     7561 ctaataaatc tgataaagat tgagcatctg tagaaatctc tgtatcagta tttatcgtga
     7621 ttcctttatc ttcatttaca agtttccaag taggtggtat agctgtgtat gtttctacaa
     7681 atgaattaag tttttcatta agtgacttct cttttatatt tccatctaaa aactctgtat
     7741 atatggcttg agctatacta aaacaaagct ggccttgttc taataatttt acatcattag
     7801 ttagtaaagc tgtgttcacg ttatcaatcg cttcaagaag agtatctttg gtgtccctaa
     7861 cagctttagg tgtgccttct ggaatttccc tacttgatac ctcgtccatt ttatcttcca
     7921 taaacccctt aaaatcatat ctttctccca aatccataga agtttttgag aaagctttca
     7981 tttctgagtc tatttcttca ataatattta acatgtctga tacatattgt ttaggctgat
     8041 tcgtttttaa tctatatgtg gtaaatatct caattcctcc aattatcaat aaaattgcca
     8101 aacaaatcca taataatttt ttctttttca tttttcctcc tatacactgc tgttataaca
     8161 gtgactaatg taaagatttt cccagcaatc atcagactat tatttacagg gaatcaaaaa
     8221 aactccttag taagcttaca cctttaggag ttcctgtttg aacggtatgc ataatacatt
     8281 taaatcaatt taacattaac acctcagtat atggtatctc tacatataca cggtcttttt
     8341 ttggatagta ctcgacattt atattgatag cacttccatt gtctaacgta gctttagccc
     8401 ggtacgtgtt atcaccatta tcatgagtga tcgtcacatc atcacatgtc cgatttaagt
     8461 tatactgttc ttgtaaaatc tgagttacca atggtacaga tgacttctct agtccagatg
     8521 aacccgtcat tcttgaaaaa attataccta taatagccaa tacaacgata cctataatga
     8581 caaacttctt attcatattt actttattca actttttatc tcctatctcc aaaatgattt
     8641 tctctcatca gtaactcatt gacatcccca atagtacacc aaagatggct ccagctaccc
     8701 ctgctatcat caaaatcgta cccatttgtt catctttctc tcgatataag taacccataa
     8761 taacagcaac agcaccaaat accacaggaa taaatgctaa tgatactacc atagaaatcc
     8821 aaccaataat caaatacagc ttccctgtct cttgtccatg tacgatttgt tccttcattt
     8881 cattaattgt ctgctcagta cttttcttta ctgtgtctgt tccggttgtc tcatctgttt
     8941 cttgtaatgc tccgcaaaac tggcaatact tactttcatt tgttatttct ttaccacatt
     9001 ttctacaata catgtcttct cctcctaaaa tcattcaatt gcttattagc taactgttta
     9061 ctttattaaa tacatcagaa aacagctcat ttattggtac acttaatatc tcagaaagca
     9121 ttttcatttg atagggttta ggaatcgttc tccctgtttg ccacgaactt acacattgct
     9181 gtgtaacatt catttttttg gctaactcag tttgggaaag tcctttttct tttctgtatc
     9241 ggctgagatt acttactttt ttcatgattc tcccctcctg ttttattata tacaacaata
     9301 tgatgtattt caactcataa aatatataaa tacttcaaat gtcattacaa atacaacaac
     9361 ttgttgtact ctactgagaa ggggggtgta ttaatgaaac agaagcaata tgcaaaggtc
     9421 attagagaaa agcgaaaagc actcgggtgg acacaaaaag aattagctaa aaaaatcttc
     9481 tctacacaac aggcagtagc aagatgggaa aattctgtaa cagaacctaa cctcgatagc
     9541 ttaacagctc tttctagagc cctaggaacc cctgtaagcc attttctaga caatgttgac
     9601 atagattatg aggaagagtt tttggctctc tatcgctctc ttagtactga agatgcaatt
     9661 cgaacaattg actatatgaa gctattaaaa aggcaagaaa atgaacgcaa tcagctattg
     9721 aaagattgaa aaataaataa cccaccgaac tttaacggtg ggtgtattga gatgaaataa
     9781 gattaagagc tatggataac ctgtctagtt taatataatt gggtctcttc tattccttac
     9841 tctccgtcca tcatctcttg ttacacttgt aaattgataa ataggaacta attcaactcc
     9901 tgataatatc aattctttta ttacttcatc tatccctgcc cctttcgcta gatatactaa
     9961 aaaactactg cttgctttca cattgtatag tttcttaata tccttagaag ctcgttcaag
    10021 agtgaatcct tgtttaacaa agtagcctct gttttctatt aaagcatttt tcacgctgtt
    10081 atccctgaca tttcgtaggc gttcacaaac agtgttaata agttcttttt ctgtcattag
    10141 atatgtccct tgccacgata agccctgtaa aacttcatgt gcttcatcta aaatcaattg
    10201 tttttccttg ctaagttctg atcgggaatt ttgaggaaat actcttttag cctctttttc
    10261 gttaaaacat atcttaaccc attcataaga aaaatattga tatgtaaaat gaaatttttc
    10321 cagaagtgga aggatatctt cattcaattt ttgaatcaca gaagttgcat taaaaacgtc
    10381 taatcgatag acattgcttc tcttatgttt aaagtttcct aacgctttct cttcctttaa
    10441 cctatttagg tattcgagca tcttcaaagg aacatcttca tcatctaatt tttttatcaa
    10501 tcctataaaa gtcataagtg atagtaactt attacattta tctatgtcat aagttttacc
    10561 atagtaagaa ctcatttttt tagctaattg ttcccccgac aaaatacaag tcacactttc
    10621 cttactatca tcaaaaaaat taacatcaga aagcaagaca tcatagacac gtcgcatttc
    10681 ctctagataa ttccttattg tcctgaaaag tttgtctttc attgattcaa gagtgtcaaa
    10741 aagtactttt gattcctctt tcaattttcg aaaatgtgta ggatacaagt ctaggttctc
    10801 taatagccaa ttaaatgttt ctacccgact gtctttcttt aaaattagca tcacaactcc
    10861 aataaaattt tcactgatat cacaattact ggaatgacaa taaaaaatgg aatgcccagt
    10921 tttactggta aaaatactag cagagggatt atgatcgttg tgaaacagac atcttaagtt
    10981 tttacttgac ttaagtaatt tattcatatc aatggttaac aatctttcat aaatctcatt
    11041 aaaagacatg tcggaggaat caaacaggca gtctttaaac cactgtttca tttcttcttt
    11101 gtcgtcattt tttatcaact taacaaaatc ggtttcattg actagttcat actctctccc
    11161 tgaatcactt tgacaatttt tagaacatgt catggtaaaa tcaatcggaa gctcagtaat
    11221 atctaacatg ttgtcttcat taattattat cactgcatct gacttatatc ctccaaaaaa
    11281 cattctattc gaagcattta cattgtcatc acacccgggg atgttctttt tcaagtattc
    11341 gtaaacagca accattttac catagtcagt aattgcttct tttaatagaa agacaatctt
    11401 gtatttttct agattttcag agtaccgaat acttttttgt atcgcaaacg cagaattatg
    11461 aactaaattg atagataaaa ccttttctat gcttaagtat ctactatcat ctttactcaa
    11521 atctactacc ttccccttct catctttaac agtgttatcg acatccagaa taattactct
    11581 ggtttccaca aaactctcct tgtcattgcc tttattcttt gtcttgcttg gaataaatga
    11641 ttgtgatgaa tttagtatct ctacaaactc atctcttgta acttctctat agttatctaa
    11701 acacctatct cttacatcag ttttttcttt ttttgtaact ggcttctcta ataatttttc
    11761 ttgatctaca taaattggaa tattaatcat tgatgtttcc atttgtgttt cctccttata
    11821 aaattctgtt aaagactaaa acatacagat aataaaaaca aactctttat tactatatgt
    11881 tttagtctta tttgtttact caacctttat accgttccat gaaactatca atatcagatt
    11941 ttttaaatct aatgaccgta tcaattttta taacaggtaa cccgtattga gaaacatatt
    12001 ttctaatcgt tcctactgat acacctagat attcacttgc ctgctgatag tccatatact
    12061 ctagagtgac tccagaaata atgtcttcta gcataggctt tagcactgta attatctctt
    12121 tcacttgttg ttcaacttgt atagaaacaa tgctatcaat gatttgtaga gacatatttc
    12181 cccctccttt cgtgattgct tgaacaaatt ttctaagaat tatcttcgta ttttttgctc
    12241 aaaataaaag tattttgtta ttaaccgatt aatcaaacaa aaaatgatta ccagttcatc
    12301 gacatacaca taatacctcg ataaaaaagg ggtgtcaaca gctttgtaaa atttatttac
    12361 aacacccctt ttttgaggta tactaatttt aggaggtgtg gtcaatatga taaaacgtcc
    12421 accaataaat tatttagaac gaaaaaagat actcggaaca aaaataaaag ctataagaaa
    12481 gagtaaaaaa ttaacacaac cagcatttgg tcttatgatt aacaacggtc aattaattga
    12541 caaaaaaact atctacgaat gggagaaggg aacctattta ccaataccag agcgattatc
    12601 ccgaattgct gatttgggaa atatgagtat agaggagtta gtttgtggca atgtagaaga
    12661 atatattttg ggaattattc tttatagaga tagcattgta ctagatggta taacatttcc
    12721 agataaaaac ctgttccagc atcttcgtca acagttccca ccagtacact ctaatttaga
    12781 tacatggctg gatagatatt ccaaattaga accagagatg caagaattta ttgctaacaa
    12841 gacttgtaat aaagttaaaa atgaaaaaat tagtcttttc aatatcttaa aaatagaaga
    12901 attattcatc aatgctattg tagaagaatt tgacaataac attcttttcc tcactagcag
    12961 tatagaagaa ctactagaaa gaatggtaga tgaatggcta cctattcaat tgaaagacat
    13021 gtcttatccc gaagaagctg tgagagaaat tactgataat ataaacaagc tagaacaaac
    13081 gatttcatca attgggaaaa aatacactaa gaaaaaaatg aagggaggtg ataccatcta
    13141 gtggtaagta ctccttgtaa actaagagga gatgatttaa tggcaaaaat atcaaagtac
    13201 aaaaagaaaa acggtcaagt ggcgtggatg tataaaggac acattgccac cgatccacga
    13261 actggtgaaa aaataaatac tacgagaaga ggttttagta gcaaacaaga agctcaaaaa
    13321 gattatgacg agtacagaca tcaaatatta tacggtgtta aaaagaaagc acctgatatg
    13381 acatttgaag acctgtataa tgaatggata actcatcagc gtaccagtgt taaagcttca
    13441 acaatcgcaa tctcagtaag atacgcaaat aatcaaatac ttccagcatt tggtaagctt
    13501 aaactatcga atatctctgt cccatattgt caaaaagtgg tagatgaatg gcacagtaaa
    13561 tatgaaagtt acgattatat gagaaaacag actgcacaaa ttttacgcta cggggttgca
    13621 atgcaatata ttgacaataa tcctatggaa aaaacacttc ttccacgaaa aaaagagtat
    13681 gagaaaaatc gtaaatttta ctcaaaagag gagcttaata atttactgga tgcttttaaa
    13741 gattttggta acatgaaaca atacgccttc ttcagattat tggcatacac aggtatgaga
    13801 aagagtgaag tactcgcttt acagtggaaa gacatagaca cgtttaataa agaactacat
    13861 gtcaataaaa ctcttgctgt agatgaattt ggtaaagtta taattcaatc tccgaaaaca
    13921 agagcttcta gacgagttat ctctttagat actgagactc tttctatcct caacaactgg
    13981 aaattacagc aaaaagaaga gtatttaaaa cttggataca atactagctc taaagagcaa
    14041 catgttttta caacagttaa aaacactcta tacattccaa acactgttaa tgattggtta
    14101 agatatattt tgaaaaaata taacttgcct cgtattacac ctcatgggtt tagacataca
    14161 catgctagtt tattattaga agcaggagaa tctgtcaagg tagttcaaca acgattaggg
    14221 catgaaaata gtaaagtgac attagacatc tatgcacata ttacaaataa tgcacctaag
    14281 aaaacaggtc aagactttgc tgatatgatg gctcatcagt aaaagagctg gtcaaaatct
    14341 ggtcatttct agtatacagg caaaacaaaa aagctagaac ccttatatat caagggttct
    14401 agctcctata acaggtttac ccaacactgc cttccatctc ataactgatc aatcgattga
    14461 gttcgactgc atattccatt ggaagttctt tggtgaatgg ttcaacaaag cccatgacga
    14521 tcatttcagt tgcttcagat tcggtcaggc ctcggctcat cagatagtag agttgttctt
    14581 ctgagatttt tgagactttg gcttcgtgtt ctaaagagac ttggctgttg tggatctcat
    14641 tgaatgggat cgtatcggat ttcgaccatt cgtccatgat gatcgtgtca cattcgatat
    14701 gagagatcga acccgcactg tttttggcaa aggttacttg tcctcgatag tttacttctc
    14761 cgccgtcttt tgaaattgat ttagagacga tagagctaga tgtatttggt gcattgtgga
    14821 tcatttttgc acccgtatct tggatttggt ttgctcctgc aaaggcgatg gagagcatgg
    14881 tgcctcgtgc accttttcca tctaagtaaa cacttgggta tttcatcgtt gtttttgcac
    14941 ctaggtttcc gtcgatccat tcaacggttg cgccttcgta tgcttttgct cgtttggtta
    15001 ctaagttgta cacattgtct gaccagtttt ggatcgttgt gtaacggcaa tacgcatctt
    15061 ttcttgtaaa gatttctacg atggcggcat gcaggctgtt acttgaataa gtaggtgccg
    15121 tacaaccttc gacatagtgg atgcttgctc cttcgtcaac aatgatcagc gtacgttcga
    15181 attgccccgt gttttccgca ttgatccgga agtacgtttg taatggaaca tcgactttga
    15241 cgccttttgg cacgtaaata aaggtcccac ctgaccatac ggctgaattc agcgctgcta
    15301 atttgttgtc ggttggcggt acaagttttg aaaagtactc tttgaataat tcagggtatt
    15361 ctttcaaagc agagtcagtg tcagtaaaga cgattcctaa cttttcgaat tcatctttca
    15421 tattatggta cacgacttct gattcatatt gtgcggaagc accggctaga taagctcgtt
    15481 cagcttctgg tataccaatc ttttcaaatg tatctttgat tttttctggt acgtcttccc
    15541 agtcacgagc gggtttgtca cttggttttt ggtaatattt gatggcatcg aaatcgatgt
    15601 ctgaaaggtc ggggccccat gtttgcattg gcattttgtt aaatgtttct agagatttca
    15661 gacggaattc aagcatccat tctggttcgc ctttgattct tgacatctca cggatcactt
    15721 cttctgtcaa gccttctcct gtactgaaaa ccggttcgac atcatcgtga aacccgaatt
    15781 tatattcttc taattctggt acgcccatgt tctcactcct cttccttgtg gtaatgatgg
    15841 aaagctgcgg taccatcgtt ttccattgct tttcctagtg ctttccaggc aagtgtcgca
    15901 catttgatcc gagcgggaaa tttagctaca ccaccaagca tagcagcatc gcctaattgg
    15961 tcgggatctt tgacttcttt tccttggaca agctgtagaa agtctacagt taaatgttct
    16021 gcttcttcta ttgattttcc gatgacggcg tctgtcatca tcgaggcact tgccgtactg
    16081 atggagcagc cactgccgtc aaaggcgata tttttgatga ttccgtcttt tacatcgact
    16141 tgcaattcga tcacatctcc acatgtgggg ttgttcaatt cgatcttgct tgtcgagtca
    16201 gtcaagcttc cacgatgatg cggatgggaa gaatgatcca agatcacttg acggtataaa
    16261 ttgtctaatt tagatagtcc catgttggaa aaactccttt gttgccatga ttgcttcaac
    16321 taaacggtcg gcgtcttgcg ttgtgttgta gaaataaaag ctcgcgcgag cagtcgctga
    16381 tacttcaagg tacttcaata gcggttgcgc acaatgatga cctgctctga cggctacccc
    16441 ttccatgtct aaagctgtcg cgacatcatg gggatgtaac ccatccaaat tgaatgcaac
    16501 gactcctgtc cgaaaattcg ggtcttgtgg accataaaca gtcaatccat caattgcttg
    16561 taattttggc aacacataag cggctagttc ttcttcatat cgatggatat tgtccatacc
    16621 gagtttttgc aaataatcga ttgcatggcc taatgcgata gcgccggcga tatttggtgt
    16681 ccctgcttcg aatttccaag gtagttcttt ccatgtactg tcgtataatt cgacaaaatc
    16741 gatcatttcg ccaccaaatt caacaggttc catttcttct aaccattttc gtttaccata
    16801 taaaacacca atacctgttg gtccgcacat tttgtgtccg ctgaaagcaa agaaatcaca
    16861 gtctagtgct tggacatcaa tggccatgtg cggggcagat tgagcaccat ctactacgat
    16921 gaccccgccg ttttcatgga caagttcagc taattcttga acaggattga agacacctaa
    16981 gacattggat acatgagcaa tggagacgat tttggttttg tccgtaatct ttttcgctgc
    17041 atcctccata tccaggaagc cttcttctgt tagttcgata tatttcaaga cagcacctgt
    17101 tcgttttgcc aactgctgcc acgggataac attagaatga tgttccatgt aagagagcac
    17161 tatctcgtct cctgctttga tatagcggtc gccgaaggtt ctggctaccc aattcaagct
    17221 tgtcgtcgta ccacgagtaa acagcacttc tgctgtttct tttgcatgga tgaacgcccg
    17281 tactttttct cttgcttgtt cataatcatg ggtcgcgcgt tctgctaacg tatggacacc
    17341 gcgatgaaca ttggcgttat cgtgttcgta atagtacgct aatgcctgga gtacttgttt
    17401 tggcttttgg gtcgtcgctg cattatccag ataaactaaa ggttcatcat tgacgtcttg
    17461 aaataagata ggaaaatcat tgcgtagctt tttagcatcg atcatccatt caacttccct
    17521 tcgattactt cgactaattc tttccgaact tgttctacag ggattgctgt taagacagaa
    17581 ccgaggaatc ctcgaatcac taagcgctct gcttcttctt tatgcaatcc tctactcatc
    17641 agatagtaca tttcttctgg atcaactcgt cctacactgg cagcatgtcc agcagttact
    17701 tcgttttcat cgatcaaaag aataggattc gcatcaccac gtgctttatc agaaagcatc
    17761 aagacacgac tttcttgttg ggcatctgca ccttttgccc ctttcaagat gtggccgata
    17821 ccattaaagg tcaatgttcc tttttctcgg atcactccgt gttgcaaaat atgcccgatc
    17881 gtatgagggg ctttattggt tactcgtgta tcgattcctt ggatttgtct gcccgagctg
    17941 attgccacga ttttgacttc tgcgtgtgca ccttctcctg ctaaatctga gtcaaagtca
    18001 gcgatcacat gaccgtcatt catgacacca attgcccagt cgacagaagc atctcgtaaa
    18061 atgtgcccac ggcgattcat ataagaagta atattttctc ctaattgatc tacggctgaa
    18121 tatttgattt ttgaaccagc tttagcgatg acttccacga tgatattacc tgatgatttt
    18181 gctacttgtt ctttggttgt ctggaaacgt tccagataag aaaattcact atgttcatct
    18241 gccacgatca acacatgctt gaagaagtgc tcatcggatg cgccatcttg aatgaataag
    18301 gactcgagtg gttcatcgat cacgacattt ttaggcacat acaggaaaat accgctgttc
    18361 ataaaagcta catggagtgc agtcaattgg tcttcgttca tgtttactgc ttttttcata
    18421 taatattctt ggactagttc tggatattcg atcattgcag tgaacaagtc ggtaaaaatg
    18481 actccttttt ctgctaattc cacaggcagt tgttcaaaaa tcgtccatga accttgttgg
    18541 acaagcacag gattgtcttt cattgcatca aatgccggaa tcgtgcctgt ttcactgatg
    18601 gtttgtgttt ctttcacatc aaataacgac cagcgatgga atttcacccg atcgatatgc
    18661 ggcaatggca gttcatctgc tttcgctagt gcgtcttgac ggaaggttct catccaatca
    18721 ggttcgcctt tacttaaaga aaaatcattt accgcgtcaa gataatcgag ccagtttttt
    18781 tctttcattc ttgctccccc ttacgcttct tcttctttat agtcgattcc taattcttta
    18841 ctgataccag cgtagccttc tgcttccaga cgtttagcta ggtcagcatt ccctgtcatg
    18901 actactcggc cttccatcat gatgtgaacg acatcaggtg tgatatagtt caataatcgt
    18961 tgatagtggg tgatgatcaa tgcaccgaaa ttgtctccgc gcatttcatt tactccttta
    19021 gcaacgactt tcaaagcatc gatatccaga cctgaatcga tttcgtctaa aattgcaaat
    19081 gtaggttcta acatcaacaa ttgcaggatc tcattccgtt tcttttctcc gccagaaaaa
    19141 ccttcgttca gataacgttc agccatttct tctggcatat ttagtaaagc cattttttca
    19201 tctaactttt tcaaaaatgc cataacagaa attttgtcgt tttcatcacg tttcgcattg
    19261 atcgctgcac gcatgaattc cgcattcgtg atacctggta tctcacttgg atattgcata
    19321 gctaaaaata agccaagtcg cgcacgttca tctacttcca agtctaaaac atttttcccg
    19381 tcaaacaaaa tttcgccttc tgttacttca tagtttggat tgcccatgat agcggcagat
    19441 aaggtagatt ttcctgtgcc gttaggtccc atgatggcat ggatttctcc ggttttcatt
    19501 gttaggttta cgcctttaag gatttctttt tcctcgatcg acacatgtag attttttatt
    19561 tctaagacag acatgcatta tacccccaaa ttctctttcg ttctcactca ttttagacta
    19621 attgagaatg aagcgcaatg accttcctta ctaaaatcaa atatctttta tttattatta
    19681 aacaattttg atttctaaat tagaataggt ataaaaaaga tgagaaataa gccattacag
    19741 acttatttct catctttttt gttccatacc ttattttgca tcagccttta ctggtttaac
    19801 agagccgccc catttgtctg tgatccattc ttggacttct ttgcggtgaa gcacttcaat
    19861 cagttttttg attttgtcac tgtcttcatc acctttacga gtcgcaataa tattcacgta
    19921 aggagagttg tccttttcaa gcaatacggc atcttctaat ggattcaacc ctgcgccgta
    19981 agcgaagttt gcgttgattg caactaggtc accttcatca ttttggtacg tagaagctaa
    20041 aagtgatggg tcgatcgtat ggttgaactt caagttctta gggttttctt caatatcatc
    20101 gaatgttgct gtttccagat ctactccatc tttgactttg actaagccag catcttgtag
    20161 aattgtgatg atgcgtcccc agtctgattc agaatttgaa gtaatgattg ttgcaccatc
    20221 ttttaattcg gaaacatctt tgactttttt agagtacaag cccattggtt cgatgtggac
    20281 agcaccggca ttgacaaagt catatccttt ttctttgatt tctttgttca aataaggaat
    20341 atgctggaag taattggcat caatgtcgcc ttcttccaaa gattggttcg gtaatacata
    20401 gtcatcgaat ttgacgattt caagatcgat tccttcatct ttcaataatg gtttcacatg
    20461 ttccaaaatc tctgcgtgcg gtgtcggtga agcgccgact ttcaatgtcg tgtcgtctgc
    20521 tttatttgct gaatctttgc tgtcgctgtt gttaccgcat gctgctaatc ctacagtcag
    20581 caaaagcgct gctgcaaatc caaaaatttt ctttttcata tcctacatcc ccctatatcc
    20641 tattatcttt tgtctgtttt cttagttaag aaatcaccga ttccttgaac gataaatacg
    20701 attagtaaaa taattaaagt cgcaacgaat gtcactgtta gattaccacg ctggtagcct
    20761 tcctgccaag caagacctcc aagtccacct gcgccgatcg cgccggccat cgcagtaaat
    20821 ccgatcatcg agatcgttgt aactgttaat ccagaaatca atgcgggaat actttcaggt
    20881 atcaagacct tccagatgat ttcccagtaa cttgctccca ttgcatctgc tgcttccagt
    20941 acaccagggc tgacttcacg aaaagcaatc tctactagac gggcataaaa tggtgctgcg
    21001 gataaaacaa gagctggaat ggctgcttgc gcacctagca tagtgcctac gattgcttta
    21061 gtaaatggaa tgatcaaaac catcaggatc ataaatggcg ttgaccggaa aatattactg
    21121 atgatcgata cgattccata aatgattcga gcatacggtt tgtttttgcg tccaatagag
    21181 taaaggatca atcccaaaac taatccgatg atcgtcacta agaccattga gattaatgtc
    21241 atatatagtg tatcaaggat agcctgattc atcgtttccg ggttgatttg tttaaaatct
    21301 agatatgttt ctgaaaagct tttatccacg atggatcacc tcaattccta ctccttgttc
    21361 tttgatgaac acttctgctt gatctaattc tttggtttca ccagtcatca agacagtcaa
    21421 tgaaccaaag gaaccttctt tcacttgttt gatctttcca tacacaacgt tgacatcgat
    21481 gttatagcgt cgaatcgctt gggaaatgac tggctcgttg gcatttcttt cgctaaaggt
    21541 caaagttgcc aaacggccgc ttggattttc tttgatgagt tcagctaata gttctgtcga
    21601 atcagcttct ggttcgatgt cttgttgtac aaagcgtttg gttacttctt ttttcggttg
    21661 tctgaagaca gtcaatacgt ctccttcttc tacgactttc cccaactcca tcacagcgac
    21721 tttgttgcag attttgcgga tcacattcat ttcatgtgtg atcaagacga tggtcaaatt
    21781 caatttctta ttgatcgcta acaataagtc taatacttct tctgttgttt gcgggtccaa
    21841 tgcgctagta gcctcatcac aaagcaggat ctcaggatca tttgccaatg ctcgtgcgat
    21901 accgacgcgt tgtttctgtc cgccggaaag ttgtgaagga tatgcttgtc cgcgtccttc
    21961 taacccgact aaacgcaaca gttcttctgc ccgttcttta cgtttgctct ttggtacgcc
    22021 agctaattcc agcggcagct ggatattttc aagtacagtt cttgaccata acaggttgaa
    22081 atgctggaag atcataccga ttttctttcg gaatgtacgt aattctttgt tttttaattt
    22141 tgtaatatct tgatcgttta cgatcacttc gccgctcgtg ggaagctcaa gtccattcag
    22201 gagacggact aatgtacttt ttcctgcgcc agaatagccg acgattccat aaatatcccc
    22261 tttttcaacg tttagtgaaa cgtcattgac ggcttggatg tttccgtttt tcccattgaa
    22321 tgtctttttg acattcgtta gttggattaa tgacatgcca ttcacatctt tctcttatga
    22381 tttttcaaac aaaaaagcct tcgccctctt gccttaagca aaaggacgaa agcttgaact
    22441 tccgtgttac caccttgatt taccgttact tcgcaataac agcctcttcc agtacttgga
    22501 cttagcttct ttccgtatac tgtcgcgctg taacgggcac tcccgtagta agtttgctta
    22561 cgctcgctta ctctgctcta agaccatctt ccatctcatt ttcgttaccc attttcagca
    22621 aacagggctc tcttcaaacg tccgtgacat gtactcttct tttcaaagct ttctcgtttc
    22681 atataggatt gcttatgatt atagcaactg gaagaatcag tgtcaacttt tttcaagtga
    22741 ttttctgatt ttataattcg tcaaattctt ttggatcaac atctttgaaa cttaagatcc
    22801 acgcattcat ttcatctgaa tcattcaaga tattgatatc ttcaccgatt ttatcattaa
    22861 cagaagaaac tgtacccgtt agcgggctgg caaattcatt gaccgctttt tccgcttcaa
    22921 cttcgatcag aggttcatct ttttttagcg attgtcctgc ttttggcaga ttggcaaacg
    22981 tgatgtctcc aagttcttct tgcgcttcat ttgtcaaacc aacacagtat tcttttccat
    23041 taaataagat ccaaaggttg tcctttttct tcaaatgctt gcctgccatt ttatatcagt
    23101 tctccttcat aaattttttc attgaatcca attgcaacaa gctggtcctc tcgtaagatc
    23161 agtggtcgct tgatcagcat accatctgtc gataagactt ggctcgcttt tgaagccgta
    23221 aactcgccta cttgatcttt cagtccaagt tcccgatatt tcatcccgct tgtgttgaac
    23281 aggcgacgga ttggtacttg actcgtttct agccaagtct caatcgttga ggccttcggt
    23341 acttctttga tcatatcaac ggtttgataa ctaacgccat gctggtctaa ccacgctttg
    23401 gcttttttgc atgttgaaca tttcgggtac cagtaaaagg tgtacaattt tcttacctcc
    23461 ttgaagatct tgcaggtgct tcattttggt atctcatcga taatatcaac ccgataccga
    23521 tcatgttccc taaaatcgag gatcctccct gactaatgaa aggcaatggg atccctgtta
    23581 aaggaagtaa tccgatattt gctccaatat tctcaaagac atggaacagc agcatcatga
    23641 tcaaaccgct tgcgatatag gcgtaaaatt cattattcgt atcgaaacac acccgaatca
    23701 tacgatagat taaaataaaa tacaagaaaa tgacgaatgc accaccgata aagccgaagt
    23761 tttcaccgat aacggtaaaa atcatatcgg actcacgaac aggcacatag atattgctta
    23821 cgttgaatcc tttaccaaac aagccaccgg taccaattgc caaaagtcct tgggccggct
    23881 gataactcat tcctgacgta tcatggaaag ggtccagcca tgaatcaata cgtgcaaact
    23941 gataagattt gaatccaact ttataaagca agtctcttcc gccttcagtc gtaaccaaga
    24001 agatcgttcc tgctccaacg actactgcca agattactac aggtgcgatg atgcgccaag
    24061 agattccaga catcaggaaa atcccgccaa agatcgcaag aaagacaagc atcgttccaa
    24121 agtcatcttg ggccatgatc aatgctaaaa ccggtattgt cacgatcaag agcttcccaa
    24181 tcagccaaaa gtccgatttc atcgtccgtt cttttacttg cgtattatgt ttagttacga
    24241 tcagtgccat catcaagatg tacgcaatct tcatcaactc tgctggctgg aaagtaaacg
    24301 caccgaatcg aaaccagttt ttagaccctg ttgaagcagc taaattctga tcatagaatt
    24361 tgagcaagag tcccattacc actaacccca aaccataaag gtaaggagtc agtttccaga
    24421 tccatttgga attcaaatgc atgatgacaa cgattgctgc cgctccaact aaataccaga
    24481 caacttgcat ccctacgcct ttcaagactg ctggattgtt cggatcatgg ctaagtgcta
    24541 catataatga gagcagacca atcaaacata acagaaagac tggtaaaatc acgccataat
    24601 caatacgatt atcgttcgaa gcttttaatt ttttttccat gtttcatccc ttttcttaaa
    24661 aaccatactg ctgattatta tagcggtcca gttagataat ggaaagtctt tccatagaca
    24721 tttgggaaaa attaactttc cgtttgtgca gttgcttgag caaatgcagt acaaaagcct
    24781 actgcttatc tttagtgtat catagaactt tttttgatac atgcaattat ctaccagctg
    24841 agattctcct cgctgtgaga agtttctgtg ctttcattgt atcgaaggat ctcttcggca
    24901 atctctagca gctgatcaga aaccagattg gttcgttgga tgaaataaaa atatcgatgg
    24961 aaattcaacg gagtcattgg cacattttct ggaacagagc gcttagacaa aatcgagcga
    25021 ccgattcctt ccttcagcaa cgcaacaatt acatcgttac ttttcacgat catcttctta
    25081 tcttggatat tcatctcttc aaaataacgc tgcgtgtaat gaaaaacacc agagtttgct
    25141 tctcttacaa gccacaattt gctttttggg tccccagcga tgactagctg gtcttccatc
    25201 aaagagtatc tttgtacgcc ggaagtctct aatggctttt cgataaaacc aaaatcggat
    25261 tcatgtttcg ctacttgttc taatgattca tgagaattcg tgatttcgat ctcaaaatgc
    25321 actttaggaa accttttgat cagatgtttc atcaactgag gcaaaagata gacagcaaag
    25381 gtgtgggaag caacgatccg acatacttct tcttcatttt gttcattgag caatttttgc
    25441 tgagtttctt cccattcttc taacaaaacc agtgtccgtt catataataa gtcggcttgc
    25501 ttagttggaa gcatctcttt tcttccgtta cgttgaaaaa gatcgatatt caattcccgc
    25561 tccaactgtt tgatttgatt cgagactgct ggttgagata aaaacagtac ttctgctgct
    25621 ctggaaaaat ttcttgtttc atatactgct cgaaaagtcg ttaataactt aaacatggca
    25681 ccacttccat aactttttat gataattact ataaaaacta tttgatttaa atatacaaaa
    25741 aaccatctat aatagaaatg tacaacaaaa cagttgctga tccaactagt aacttagatg
    25801 aagacaatca gctgtctgct tgctcgtaat catacattcc tattcatttt acaatgtatt
    25861 cgttcatctt ggtactaaaa tctattaaat aaaaaggaga atattatata tgaagaactt
    25921 tttgaaaatt attccgatcc cgatctgcgg gttgatcctt gggttagctt cccttggaaa
    25981 tctgtttaaa gactatcacc atgttgcttt aggcaatcta actggcggta tctctatgat
    26041 tcttatgata ttcatttttg ttaaattgtt tatcttattc gaacacacga aacaaacgtt
    26101 gcatgatcca atcatcgcct ccgtttcacc aacttttacg atgtcactca tggttatttg
    26161 tacttatttt gtttcatatg aaagtattgc accaattgtc aaattcattt ggctgtgcgc
    26221 tgttatcttc caagtgatcc ttgtctttta tttcaattat caccatgtta tcaaagctga
    26281 tctttcaatt gaagcaattt atccaagctg gtttatcatt tacgttggat ttggggtcat
    26341 cactgtaact gccgggaact tcttcccact tattggaaaa attttctttt ggatttcatt
    26401 gatctgctat gcgttcttat tgccgatcat catcaaacgt gtctttttcg taagaaatat
    26461 ggctcatccg acacgtccgc tgattacgat cgttgcagca cctggttctc tttgcctaac
    26521 aggttatctt aaaaactttg ctgaacctaa tttttatctt gtcgtagcat tgttcgcttt
    26581 atctcaagta ttgtatttcg ttgtgctgtc tatgcttcca cgtttgttca agcttcgttt
    26641 ttatccaagc tatgcagcct ttacattccc gcttgttatc tctgcaacag ctatatttac
    26701 tactgttcat tacttcaaca gtttaggtat ctatagtagc gtattggatt tcttaaaagt
    26761 tgcggaatgt ctgtttgcaa gtgtagttgt cttctacgtt cttgctcatt acgtacgttt
    26821 cttaattaaa gaacatagca aacatggaaa atttgtttct aaaaaaatcg cttaataatc
    26881 gattcaatag gttgtgaaaa agctgttctg catcaagtaa taagaacggc caaacaaaaa
    26941 cagctgttca tgtttttgta ctggttgggc ttattaccgc agatgcaagc ttttgaacac
    27001 cgtttaccaa gaggtcgtaa aagaagtggt cagcttcaag aaataagaag gaatttacga
    27061 aaattgcttc tcaaattttt gtgaaatttc ggcttatttc cgtagaagct acttctggaa
    27121 caccgtttat tcgaaacaag aggtcgtaca agacttttgt cacgacctct tgttcttttg
    27181 tcaaaatact ggtttagtgc tactatgttc gagtatgctt ttagtattta ttgacgaaag
    27241 gaaccgatca aatgaaatca ttgtcacatc caataaaatc tgtaaaggat tcagcggtcc
    27301 gcgaaatctt acccggttta ctgctttctt ttgccatcgc tgccttcagc aggcttcttg
    27361 ctatttatct gccacagtta ggtggagcga ctattgctat tttattgggt attttattag
    27421 gaaatacttt ttttaaacag cctgttctag caatcggcac aaaatttgct gaaagcaaac
    27481 tattagaatt ctctgttttt ttactaggtg caactgtcac agctcaaacg attgctcaaa
    27541 ttggtgtaaa aggaattgtt tttgtgttac tgcaaatgtc agtcactatc atcggtgctt
    27601 acttgattgg taaaaaactg caattcagcg atacttcttc tttgatgatg gctggaggaa
    27661 acgctgtttg tggttcttct gctattgctt caatcgcccc ttccatccat gcgaaagagg
    27721 aagaaaaagg acagatcatc acactagtca atctactggg tactgtgatg atgttgactc
    27781 tcccttttct tggattacag ttgtttggtg gaaatctcat tgaaaaaagt gcacttttgg
    27841 gtggtacact ccaatctgtt ggtcaagtag tcgctggggc aagcttactt gacaattctg
    27901 ttgtcgaatt cgccatgcta tttaagattc tacgtattat gatgctcgtt gttgttgtct
    27961 atctgtttga aaaattcatg cacaagaaac aaccagctct gtttgaaacg ccaactgata
    28021 cgcagaaaaa acgaaaatta ccgcttcctt ggtatgtatt agggtttgtg atcttttgtt
    28081 tggtcaacag cttgttttct ttacctgtag ttattgacca atcggcacat tttatcagca
    28141 gctggtttga gatcactgct ttagcggcaa ttggtctgcg tttagacttt gcaaaattca
    28201 tgaaagaagg tacacgcttc ttatcttatg gattagctgt cgggcttctc caaacagtga
    28261 tggctttact atttatttgg ctgatcaaag tttagaatga acatgaaaaa acagttgtga
    28321 ttctcgcatg gaacaatgtc cgaatcacaa ctgtttttaa ttttgcagat atccttctaa
    28381 caacaacaat tggcgtttga tttcaacccc atctattgcg tttcccatat atcctgtcag
    28441 ttttccattt tgcccgatca ctcgatgaca aggaataacg attggcaatg gattggttcg
    28501 atttgcctgc ccaatcgctc gcacagcttt cggactatca acagcaacgg ctacttcttt
    28561 atacgttcgg atttctccat aaggaatggt cgacaaagct ttccagacat tttgctgaaa
    28621 aggcgtacct ctctttatag ataaaggaac atcaaattct tttctttttc ccgcaaaata
    28681 ttcttcaaac tgttcttgtg tgcgcgttaa aattcgctga ttcgctgatt cgctttctga
    28741 aattggctga aaagatacag cagtcaatcc ggattcatct gcatctaacc ataaaaagcc
    28801 gataggtgtg tgtattttca ttttgtttgc tcctagtcaa tagactggaa cttcctcctt
    28861 tttctctatc caaaactact tgccaactaa taaaaattgt tcttaaaagt ttgataaacc
    28921 gaggaaacat ggtaaactaa atacgttagt ttacaaaaag aatacctgtt cttttacgta
    28981 aaatcaaatt ttaaaggtgt tatttaaggt ttattaaatt ttgaatgtaa accatatata
    29041 aacatacgat tgaaaggata gaaacgatga aagtatcaat tgttgtccca tgttttaatg
    29101 aagaaaaaac tgttcctctt ttttttgatg aggttgaaaa attcaaaggt gcccatgagt
    29161 tcgaatattt gtttattgac gacggatcaa aagacggtac gttagcagca atcaagaagc
    29221 tagcctcagc ttatccttat gtccgctttg tctcattttc cagaaatttt gggaaagaag
    29281 cggctctgta cgctggattg caagcttcta caggagattt agtgaccgtg atggatgttg
    29341 atctgcaaga tccgcccgaa ctgcttcctg agatgatcaa ccggatcact acttctgata
    29401 tcgattgtgt cggcacccgg cgttcgactc gtgaaggcga gcctgcgata cgcagtttct
    29461 ttgcgaaaaa attctaccag ttgatcaata aaatcagcga tacagaaatg gtcgatggcg
    29521 ctcgtgattt ccgcttgatg actcgtcaaa tggtggatgc cgtcctagaa ttaacagaat
    29581 acaaccgatt ttcaaaagga ttatttagct gggtcggatt taaaacagaa tatatttctt
    29641 atgaaaaccg cgaacgtgtg gctggcgaaa catcttggtc cttctggaaa ttattcaact
    29701 actcgattga tggtatcgtg aacttctcgg atgcaccgtt aacgattgct tcatttatcg
    29761 gcgctttgtc ttgtgtcggt tctggtattg caattttgtt cattattttg cgggcattgt
    29821 tgtttggtga tcctacatca ggatggcctt ccatggtctc gatcttcctg ttcattggtg
    29881 gaatccaatt gttatgtctt ggaatcatcg ggaaatatat tgggaaaatc ttcttagaaa
    29941 cgaaacagcg tcctgtttat atcataagag aaacagaaaa agtgaagcca aatgaattga
    30001 agcctcacca ataatatacg tcaaatgaag taaacatttt tttaaatgaa aaaggactgt
    30061 gacaaaagtc ttgtcacagt ccttttttcc gaataaatgg tgttccagaa gtagcttctt
    30121 cggaaataag ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat
    30181 ttcttgaagc tgaccacttc tatcacaacc tctttcatat cttattactt cttcattgct
    30241 gcttttagtg ctgctgctaa tgggctttct tctggttctt ctgcttgtgc atattttttc
    30301 agcaagcgtc gttcttcatg tttggtcatt ttcttcttct gctctttttt atcaagcaat
    30361 ttttctgtcg ttccatcgta tttacaacgg aaataagcac cgtttttacc ttcgatgatt
    30421 tccattttcc ggtgacattg cgggcatcga tgattagaga cttttggatc ttttcttctg
    30481 cggtagttgc aatctgaatt ggtgcagaca tagattttgc cgtcacgtgt gtttttctcg
    30541 cgcagattgg ccccacattc tgggcatttc ttttgggtaa tcgagaaatc ttgatattct
    30601 tgtttgcttg atttgatctc attcaccaag cgttttgttt ctttttcgat tccattcaag
    30661 aaggttcctg cttgtttctt tcctgcagca atagcttcaa ggtctttttc ccagctttct
    30721 gtcaaatctg gtgttactaa agagggattt accaatacta ataattgctt acctttagga
    30781 gatacttgca gtccttgagg ggtacgttcc atcagttcag atttgattag tttctcgata
    30841 atctctgcac gcgtagctgg ggttcccaga ctgtattttt ccatttgacc aagcaagctt
    30901 gcttctgaca atggtttagg cggtgcagat agttcttttt tgatggcgaa atcgggattg
    30961 attctcattc ctttttccca tttgactgtt tccgtctcag tttcagtttc gcctttccat
    31021 cctgcttgga cgacacgatt ttgccgaaaa atgaatcgtt ctttaccaaa ttcaaccgta
    31081 acttttgttt ggctgacttt atggggttga gcaaacagtc ctaaaaaacg agagacaatc
    31141 atttgataga tttttcgctc ttcattactt aatttttcat aacgtgctct gttttcagtt
    31201 ggcaaaagtg catggtgatc ggtcacttta ctgtcttgga atacttttgt ctgttggacg
    31261 atggctccgt ttttcaaata ctgcttgacc tcaggagcaa agtcgctgac tgcttgcaat
    31321 cgttctttca tcgtactttt catgtcattt gtcagatatt tgctgtctgt acgcggataa
    31381 gtaacgatct tatgggtctc atacaaactt tgtacaagac ttaatgtttt ctttgcagaa
    31441 tagccatagc gttgattggc ttctctttgg atctctgtta aatcataagg caatggcgca
    31501 gattccgttt ttaatttttc ttggacttct gtgacagttc ctttgcttgt actgatcaat
    31561 tgaacaagtt tttgtgcttc ttcttgtgtt tttaaagcaa attgattttt ttgaagcatt
    31621 ttggcttgtt cttttccagc ttgcaacgtg atcgtgaaat acgtttgtgg acggaactgc
    31681 tcgattttct tttcttggtc tctcactaat gctagtgtcg gtgtctgcac acggcctgct
    31741 gataaattat ccgcgtactt cacagttaag gctctggtca cattcaatcc taccagccag
    31801 tccgcttttg cccgggcaag agcagattca tacaatgcat catattcttt cgcaggtctt
    31861 agttgcttga atccagtttt gattgcttta tctgtttgag aagagatcca taaccgcttc
    31921 actggtttat tgaaatgcac atactctaag atccagcgag caacaagttc cccttctctt
    31981 ccggcatctg tcgcaatgac tgcttctgag acatcttttc gctgagccag ctgcttgatt
    32041 gcttttaatt gatgtcctgt tttaggaagt ggtttgattc ctagtttttt agggatcatt
    32101 ggcaacgtgt ccatttgcca gctctgccat tccttattca gatcttccgg cattttcaat
    32161 cctaataaat gaccaagggc ccaagtaacg atcaccttgg gtccttcata ataatttttg
    32221 tgcttttgat tagcaccaag caccttgctt aggtctttcg caacgcttgg tttttccgct
    32281 agaattagtt gtttcataaa attcctttct gctttctact gtgatgggct gatgattttt
    32341 caacaacgca agtcccttgt attgctgtaa atcatcgtca cactcttcac accagcgctc
    32401 atctccgtca ttccaaaagg cgctgagaaa gttacttttt gcattgatat attcataatt
    32461 ttgatggatt tcgttccatt gtttttcgta cgcttgtcgt gcttcttcga aagactcgaa
    32521 tgtttcttct tcttcaatat cttcttccca gtcttcaaaa aaccaccaag gctcattgtc
    32581 cccgaacatg gtaattactt gatacatact cgtgctcctt ctttcagctt ttctagactc
    32641 atcttagtca cttttcaaga aagttgcaag aattttctct tataaaaggg tcatttaatg
    32701 aacatcttaa aattgttaca aatgaatctg attgtttaag gcaaagtagc gataaagtta
    32761 ttgatcatcc aaaaatagct gtcttctgga tcgattgttg gttcttttgt aaagtatcct
    32821 aaaaaacgta aggaaagata accgtggatc atactacgaa gttccctgct tcgatgaact
    32881 ttttcttctt tcgttaattg aaaagcctca aatatctgca aaatgatctg attcgtttca
    32941 tggattccat ctaataaaac agcttcattg gtatgcggta cactgatcag taactcatac
    33001 actgcttgat ttgaaaaagc aaaggatcga taagtttctg catagatctg cagtgcttcc
    33061 tgaccacttt ttcccacaag agcccgtcgc agctggtcat taagttcctg cagaagtttc
    33121 gctgttagcg ctgttttgac atcacgaata tttttgaaat ggttatacag cgagggagcc
    33181 ttgatatcca agcgtttggc taaatgctga aaggttattt gctgaacatc catctcttct
    33241 gctagttctc gaaagcagtc gatgattttc tcttgagaca gatttctttt tttcatttcc
    33301 atgtttcctc tcataaaata aatccttcac tctttcagtt taccacgaaa aagaaagaga
    33361 aaaaagagac tttcattgat aaactacata ttgtagttta taataaagag ctgtagatga
    33421 aaattttcag aaagaaggag tctaattggc tgcaagaata aaggaaaaat tatttaggaa
    33481 aagagaaact tgggaacaaa acttgtttgt cttatggttt ggaacattta tggctggtat
    33541 cggatttagt ttagtcatgc cttttatgtc actttacata gatacgttag gtaattatag
    33601 tacgtcacaa ttgaactttt ggagcggatt gactttttca tctactttct tggtgactac
    33661 gcttatctct ccttggtggg gaaaattagc cgaccaaaaa ggaagaaaat tgatgctgtt
    33721 gcgtgcttca ttaggaatgg caatcgtcat ttctttgatg ggttgcgtga ctagtgtgta
    33781 tcaattagtc gcattgcgtc tgcttcaagg gattttttct ggttatatca gtaatgccac
    33841 tgcccttgtc gcaactggga cgccaaaaga aaaaagtggt caagttcttg gaaccttagc
    33901 aactggttct gttacaggaa cattacttgg accgcttctt ggcgggatct ctgcttcagc
    33961 gtttggctat cgccctacct ttttcattac agggatcatc ttatttttcg tcttcttgtt
    34021 gagtctgttt ttcgtccatg aaaaatttgt cccagtgaaa aaagaaaaca tggtttctgc
    34081 caaacagatt ttcaaagact tgaaatatcc acacgtcgtc atcggtatgt tcgtcacaac
    34141 gatgatcatc caagcatcca acaattccat tagtccaatc atcagtctgt acattcgcca
    34201 attgctgcat ggacatggga atgttacgtt gatcagcgga atcattgctt cgatacctgg
    34261 gattgccact ttgatagccg ctccaagatt tggtcgctta ggtgacaaga ttgggagtga
    34321 aagaatactt gcgattggtt tgggttttgc gattctggtt tatatcccaa tggcattcgt
    34381 cacgaatgtt tggcaattag ctgccttacg ttttttgatt ggtatctctg atgcttgtct
    34441 gctccctgct gtccaagcat tgatcacaaa atattcgcct catcaagctg ctggacggat
    34501 cttcagttat aaccaatctt tccaagcaac tggtaacgta gtagggccta tgatcggctc
    34561 cagtgtttcc agtgcatttg gttatcgtgg cgtctttctt tcgacttctc ttcttgtttt
    34621 ggtcaacttc ttgcttgtac gacacaatac acaagagatc catcagcaag aaactgcaga
    34681 agaaaaagct tcaggagtct ccatagcttc agggcactct ccttctcata gacaataagc
    34741 gtaaatgaaa aacactgctt gaacagttgt cacagactgt ccttgcagtg tttttgttta
    34801 ggcctgtttt ttcaagaact cagataagag gaataatccc ttttccaagg tttctttttt
    34861 acaacagtaa cctagtcggg catgcttcgg taaatcaaag gcacttcctg gtactaatag
    34921 tactcctgtt tcttctaata aattgataca aaatgtctgg tcatcttctt cgatggctaa
    34981 tttaatgaaa gaagtagaga cgtaattggg agcgacaagt tcaactttcg gttcattggc
    35041 tacccattgt tttaaaatca caaggttctc tgtaatgatc tttttgtttc gcgccaatat
    35101 tttttcttta ttcttcaatg catgtacagc aagatcatct gacaggactc cgccgcaaat
    35161 catcgtgtag tctcgatact ttcgaaaaac ttctgccaac tcaggtccag tagctgtcca
    35221 gccaatacga atacctggaa tggagtaggt tttggatagg gaattggttg ctataccttt
    35281 ttcatagaca tctacgatcg acaagaattc acctttatcc gttaaaggcg catatacttc
    35341 atctatcaat acatatgcat ctactgtacg agcaatttct gcgatttttt ctaaagtttt
    35401 ccgatctagc aatgtgcctg taggattgtt tgcactattc aaacagatga tttttgtttc
    35461 aggtttgact aaggcttcta gctgttctaa atcaaactgc caatcttctt cttccttcaa
    35521 atgaacaaag tcaacagcgg cacctaaaga tttggggatg tcatataatt gctgataagt
    35581 aggaagcatc gaaacaacat ggtctcctgc ttccactaac gcgtatagag ctaaaagatt
    35641 agcaccagtc gctccattcg tttgtaagat gttttccgga tcgacggttt gataaagaga
    35701 agcgacttct tgtttgaaaa catctgatcc ttcgatccag ccatagtcca atggttcgtt
    35761 tttgcgtttt tcgaaaaatt tacttacgct agtcccatct aagccaacga gttcgtctaa
    35821 tgtcaatgct tcgatcgagc tttgtgcaat atcatatacc gctttctttt cccatttatt
    35881 tagccattct tctacaccga aatttgcgat tttcatgttt ctttccccct tatatcttga
    35941 tccagcctac agcaagcaac ccgattgaaa gcagtgcggc cacacaaatc agcccaatca
    36001 ttactttttc ttttcccgta atttgatgtt tggtttcacg acaagcgatc cagtagaagc
    36061 aaaaaccagg aagataggca atactacata aaaggacata agaaaatcct gctaaaatga
    36121 tgcccatcaa ttcaaaaact acagcaatcc caccgatcac tacttgtttt ttgattcctt
    36181 cttttaaaga aaactggact tgatagatcc cgacaagtag ataacaaatc aaaattgccg
    36241 ctgtacataa agaataggca aattgatagg cataatcagt aactaagaaa gtcaataaga
    36301 atagattagt caagattgca gtaacaacta acgaataagt tggggcattt tttttattcg
    36361 tttttcccca acctttcggc aacagaccgt ctcgagccat caacatcgtt gtttctgctg
    36421 ggagcatcgt ccaagacaac caagaaccaa tgatcgaaat aatcaagccg atattgatca
    36481 gcgctgctcc ccaatttccc acgattcctt ttaaaatatt tgccatagca ggttgtgaaa
    36541 tagttgctaa ctcttcttga gataagacgc cgtatggcaa gatcgaagca aggatataga
    36601 taaacaataa acaaagcaga ccaatgatcg atgcttgctg ggcttctgaa cgtttcttcg
    36661 cgcggttggc taaaacactt gcgccttcga tccctacaaa gacccacatc ataaccatca
    36721 aacaaccttt aatctgcaac cagatcgttc cttgctgccc tgttccattc actagattat
    36781 cagatacgtt accccaaaaa tcagcagtga atatattcac tttaaatgcg ataaatacaa
    36841 atattaaaaa taggaataat ggcactaatt tacagatcgt cacgattgta ttgatgacgc
    36901 tcgctccttc aactccattg tttactaata aagtcagacc ccaaataaaa atacttgcaa
    36961 ataaaataga aggaacattt tgtccacctt tgaatatcgg gaaaaattct cccatggcgc
    37021 tcatcagcat cgttgcaaaa gcaacatttc ccagccacgc agacaaccag taaccccaac
    37081 cactgatgaa gccacctaat ttaccaaatg aagcttccgc gtaaccgaaa ataccaccat
    37141 ctagatctgg acgcttttct cctaaatgat tcagcgataa taccaaagct aaaataccaa
    37201 tcccaacgat tatccatgaa aggatcgctg gccctggagc tgcagaacta gccagatcac
    37261 ttgtgatccc aaacacaccg cttccgattg acgaactgac aaccagagca accagtcccc
    37321 atttgctaat acccgtcgat ttcttttcca tttccatcac cctcacttat aaaattgaac
    37381 aaatcacttg caaaagattc ccttctattt tgcaactgct cttgcttaac aaaaagcaac
    37441 tttattcata ttattggata ttatgaactt tttacacaag tatttcaagt ataaaatgaa
    37501 taaaaattaa ttttattgca aaaaaacagc tatgctatcc aaaagaaaag gtgtttcttt
    37561 tgttagccat agctgttttg attcatttaa tatcgcttaa acgtattgta aaacttttgt
    37621 ttcttgatat gcgtggtcga tcaaaccacc acccagacat tccattccat cataaaatac
    37681 aactgcttgt ccaggagtga ttgcacgtac aggttcgtcg aatacgactt ctgcacgatt
    37741 atcatccaat aagcgaactg tcacaggaac gtcttgctga cgataacgga atttcgctgt
    37801 acacttgaat tcttttggca ttggttcatt cgtcgtaaag tggatttcac ttgcatccaa
    37861 gcttgtggca tacaatgcag gatgatggaa cccttgcccc acatataatg tgtttgtcgc
    37921 tagatctttt cctacaacaa accagggttc ttgcgaatct cctccgccac cgatccctag
    37981 tccttgacgt tgaccaatcg tataatacat caagccagca tgttgtcctt tgacttcacc
    38041 atcaagagtg accatatttc ctttttttgc tggcagatag ttgctcaaaa attgtttgaa
    38101 gttcttttca ccaataaagc agattcccgt tgaatctttt ttcttagcag tcgcaaggcc
    38161 tgcgcgttca gcaattgccc gtacttctga tttttccatg ccgcctagag ggaacatcgt
    38221 ttttgaaagc tgttcttgtg ataattggct aaggaagtaa gtttgatctt tattattgtc
    38281 tactccacga agcatgtgga ccacgccgtt ttcatcgcga gtgacttgcg cataatgtcc
    38341 agtagctaca taatcggcgc caagatccat tgcataatcc aagaatgctt tgaatttgat
    38401 ttctttgttg cacatcacgt ctgggttagg tgtacgtcct gcgcggtatt cggctaggaa
    38461 atattcaaat acacgatccc aatattcttt ttcaaaattc acagagtaat aaggaatccc
    38521 gatttgagca gctactttcg ctacatcctt ataatcttcc gtggccgtgc atacaccgtt
    38581 ttcgtccgtg tcatcccaat ttttcatgaa tattccgatc acgtcgtatc cttgttcctt
    38641 taacaaaagt gctgttacag atgagtcgac accgccgctc atccctacga caacgcgtgt
    38701 tttgctgttg tctgtcatga tatcaccatc atttcaatta gattctgaaa catctacgag
    38761 ttgaaggtcg caacttttca gtattttaca ttatacgtca tatttctgaa aatttcatcc
    38821 cttaattatc aagtcgtaaa aatactgttc tactggacct attcagtaca caaacatgat
    38881 agtcaaccaa aaaatcactc atcttttgag cattcgatat aaaaaattgg catactcata
    38941 aaaagggcca gcctttcggc aataaggaat aattttataa attgtgaaaa actatttttc
    39001 aaaattgctt cttatcgctt aaagctgcac gtctcattta caaccttttc tttttagatg
    39061 ttatgagttg ctcagataag tgattttgtt tactctaaga aaaaagggag gcaaaagata
    39121 catgaattac tttatcagtg atatgcactt tttccatgaa cacttattag gaaaaaacga
    39181 ctttgctccg cggctctttg caaatgtgga tgaaatgaac caacagttga tcactagctg
    39241 gaatgcagta ataaaagaaa ccgaccatgt ttatcatcta ggcgaccttg ctatgcatcc
    39301 gcaatatgaa aaagcaaatg cagaaatttt ggaactggtc actcaactgc aaggaacaat
    39361 ccacttgatc aaagggaacc atgacagtcg cgcttttttc cgttatttag aaaaaaatga
    39421 tcctaggctt actgacggaa gtcccaaatt ttatttttat gatgtaggtg ccatcgttaa
    39481 attcgaccat caacaatatt acttgactca ttatccgatg ttgctcgggc ctaacgacac
    39541 tatccgcaat cttcatggac atatccatca ttacagcgta cctatcgaga acgatgtcaa
    39601 tgtaggcgta gacgcaccgg aaagagaact cttaaaggaa aaactaccat ttggcactcc
    39661 gttatctgag caacaaatca aagaaatcta tgaagcaaag aggaagtacg ataggtcgtg
    39721 aaaaaactgc cctatatcaa gtattaaaca aataaagata attactcata tttttcattt
    39781 gagtaggctt attgccacag gaacattagg atcagaaatg gagttgtaac aagacttctg
    39841 tcacaactcc attccatact attcgtcttt ttgctcatgg tgttctttta ccagtttttt
    39901 ctgtaattct ttatcataat ttcgggcagc tgacgttaaa aataaaacga ttccgcataa
    39961 taaaatcccg attccggaaa acaagaacat tttttctacc cctaaacgat cagctaatgg
    40021 tcctgcaaat aataatccaa ttggacctgc caggttcatc aaagagttga agttccctaa
    40081 gacacgacct aaaacattcg attcataact ctgctggatc attgccatca gcagtgtatt
    40141 gaaatatggc gttgcacaac ctgctcctgc attcaagata agaaagtaca agaacccttg
    40201 actatcgttt ggaaccaatc cgcttgcacc gatcgtcagg cccataatga tgtaggctat
    40261 aataataggt ttcattcggt ctttccatgt tcctataaaa ctgatcagtg caccgcctaa
    40321 gagcattccg actgcgtaga ctacttccac tgctcccgcc tgtccaacgg aaccaccaaa
    40381 gtaatctagc gtcatcaatg gatacagact gattgctggc atgaacaaca gcatcacaaa
    40441 tgcaccattg atcgttatgt accataaccc tttattatcc atcaattgct gcagcccaaa
    40501 ttttgcatct ttaaaaatag taagcggaac ttccaatatt tcaggagaaa cttttgggat
    40561 cttcacaaaa atcaataagc cgacaccaaa aactgccccc aatacatcta ataaaataag
    40621 gtaattgaca ggaacgactg aaaacaaagc cgcacctaga gctggcgcaa tgatgaaatt
    40681 cgctgattgg accattccta actgtccatt cgtccttgtt atgtgagaag atggaacgat
    40741 tgtcggcata atcgactgga tcgttggcat ttggaatgtt tgtgcgaccg aacgcataaa
    40801 caaagacaca aaaactagcc aaatcgggaa ggattctgaa atcgttccga ctactgctaa
    40861 aataagcgcg aaaatcgcta caataatatc cgtgacaatc aaaagagctt ttttatccca
    40921 gcgatccact agcggtccta caaatgggct tagtaaaacc atgggaatca ttcctagtaa
    40981 agtagcaaaa ctcaaaattg tcgccgaacc ggtttctctt gtcaaatacc agatgatcgc
    41041 atattggacg accatactag tgattcctga caaaaactgt cccgataaaa agaacaaata
    41101 atttctcttc caattcgtta aaacgaccga ctgttcattt tccataaaca tccctctttt
    41161 ctttttcatt ttgtatagcg tttgcacaac aatcattata cgggattctt ttttcaaaaa
    41221 ataccttttt ccctaaataa caatcgtttc aatttaaatt tctttactta gaaacaataa
    41281 atcagcaaaa tattaaaaat aacaacatgt gttaaattta aaaataaaaa agacaactaa
    41341 tttgcgtcgt ccttacaaag ttagtcatct aacaataggc cgtttcaaaa ctagttgtct
    41401 ttttatatcc acagatcatt cgactttttc gaataaccca cggctaatca tcccatccat
    41461 cagaaaataa aatttatctt ggctcatttt ctgttttgga tctttgaaaa tattgactgc
    41521 tttcaatcca tttgctgtag tgatcgacat tttcaatgtt tgaatatctt ttgatacagt
    41581 gatttttaat ttgaatcctt ctttgctttg cggcgtggca tctaatggtc ggatcaattg
    41641 ataattgcct ccgtttgttt ctgtaaatcc attatcgcgc aatgtatatc tttttgcatc
    41701 aggatgcaaa cgatagctaa ttggtgcgcc cagtaccgtt gctgttgttt caaatgccat
    41761 gattttcacc tcgataaaat tagtttctct ttattataaa agtttatcct gatttttact
    41821 aggtttttca gttaagttcc ctaaaaaatg aaggcgttct ctcagacatc tgttcatata
    41881 agaatgactt cactagttat tttttgacag cacgaactaa ttgatcaagg aaatactgga
    41941 tgtcgtcttc ggtatttccc aaaccaaagc tgatacggat ggattctttt agtatcggtg
    42001 tatcttctcc atacattgct tctaatacgt gtgaaggctc gatatttcct gctgtacaag
    42061 ctgaaccagt agaaatagcg accccattaa gatcaagctt catcagtagc aaatcatttg
    42121 cttcgccaat taagcgaaga ttcaacacat gagggagttt attcgttaaa tcaccattta
    42181 cttgataagg gatttcgttt gcttctaatg tatcaagaat caattgctgg aatcctttat
    42241 atttgttgtt acgtgcttca cgttcttcag gtgacagcag ttcaactgct tttgccatac
    42301 cccagatccc tgctaaattt tctgtacctg cacgccgctt ttcttcctgc tccccgccta
    42361 aaagcaatgc agggatattt actccgtctc gtttatataa gaaaccgacg ccttttggcc
    42421 cattgatttt atgagcagag atacttaata aatcgattcc taattcttct ggatggatcg
    42481 tttggtttcc gtacgcttgt accgcatctg tatggaaata agctggatga tccgctaaaa
    42541 gttcaccgat ttctttgatt ggcatcaaat ttccgatttc attgttcccg tacatcacag
    42601 agaccaagat cgtatcttct cgtaacgctt ttttgacctc ttcgatcgac agattccctt
    42661 tttcatctac aggcagatat gtaacgtcaa acccctttgt ctctaaatat ttcatggtat
    42721 taagaacagc aggatgttcg atagctgtag tgattagatg tctgccttct ttttgacgcg
    42781 agaacgctgt ttctaagata gctgtattat ccccttctgt tcccccactg ttaaagatga
    42841 tctcgtgagg ttttgcttgc agactgtctg caatgatttg tcttgctgtt tccaattttt
    42901 catgcgcgtg gcgaccaaat ccatgtatgc ttgaaggatt tccaaacgtg tcttgcatga
    42961 ttgccgtcat cgcttcaatt acttgtggat gcatgggggt agttgccgca tgatccagat
    43021 aaatagtttt cacttcattc atcccttcca aattattgct aggcacattc tagcataaaa
    43081 tagcgaacaa accaaagaag agctcatttt tgtctagagg acgtttcatg ggcatagaaa
    43141 aaaggagctg tgacaaaagt cttgtcgcag ctccttgaag ctgctcactt ctgtcacaac
    43201 ttctttccct cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact
    43261 catcggtgta ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac
    43321 gattgttaag ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat
    43381 atctttgatt ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga
    43441 cgcacaggca tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag
    43501 cgttgctcct gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc
    43561 gatcacataa ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct
    43621 gttcaaatat tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac
    43681 tacgatgtca tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt
    43741 aaataaatta tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa
    43801 agtcagtact cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat
    43861 cggttcatga ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac
    43921 attgatcgtt ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata
    43981 gtaatcattg acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact
    44041 ttcttcgata ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa
    44101 ttctgttccg aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa
    44161 aatcttcaac gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta
    44221 ttcttcgata gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag
    44281 gaagtgaaac tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt
    44341 tgtcgtgtac tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca
    44401 cccaatgatt gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc
    44461 cttcacgtat acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct
    44521 catgattgcc attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg
    44581 taggaagtcc tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag
    44641 ccgtattttt cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat
    44701 aggcaaggag aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt
    44761 tcttatacct caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc
    44821 ctgacctttt ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata
    44881 actcgattgg ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag
    44941 tatattttgc tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt
    45001 gatcttcaaa aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag
    45061 tgctggctaa ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt
    45121 gattcagttg ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc
    45181 agtttgattg ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta
    45241 agataatggg cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa
    45301 acaagatttc tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga
    45361 taaaccagct acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg
    45421 agaaacagac gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt
    45481 ccttgcatat tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc
    45541 gcttcaacct ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca
    45601 atttccagaa tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga
    45661 tatgaagaat gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga
    45721 taagacgtat tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga
    45781 tatggctgtt cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac
    45841 ggaacaagca gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa
    45901 cgcagattac agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga
    45961 taaactggac ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat
    46021 cgtaactgat ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc
    46081 gttattcaaa agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga
    46141 agaattccgc caagtcagcg gaatctattc tcgcgtattg tctggaacag acgaagcaat
    46201 gcctcagaaa aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga
    46261 ttactacgga aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa
    46321 aaaaatgatc gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac
    46381 aaaagaaaaa gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa
    46441 gatcccagca ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct
    46501 ttcaaatact cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa
    46561 accagtggat cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc
    46621 atttcggaat gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga
    46681 acaatcaagc tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca
    46741 tgcatttgat aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac
    46801 agaagaagat cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg
    46861 tctgcctttt gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga
    46921 tgcaggcggt ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga
    46981 ggaattcttt gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca
    47041 acttttactg caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa
    47101 aaaccttgac gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc
    47161 gccagaaaaa agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa
    47221 ataagaagga atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc
    47281 gaagaagtta cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa
    47341 gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta
    47401 ccgagaaact ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct
    47461 gagtattaga gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat
    47521 accgagggtc agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca
    47581 tcaagtaata agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag
    47641 aaggaagtga gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg
    47701 ttttacatca taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa
    47761 ctacaccgat taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg
    47821 tttttgggag tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag
    47881 aaggttttcc atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt
    47941 tgtcatttcc cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa
    48001 cagattctgt atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt
    48061 ctagcgtata ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag
    48121 cacttgactg tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga
    48181 caggcgttcc ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa
    48241 tgatatttcc ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat
    48301 tttgttcatt tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg
    48361 aagacggtga ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc
    48421 tttccttttc tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac
    48481 ttccattttc atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact
    48541 cgatccaatc ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat
    48601 tccaatagta gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct
    48661 gctctctcat ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg
    48721 tgtttcctgc tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac
    48781 tgctattgac gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga
    48841 aagacaaact attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc
    48901 cattaccgtt accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt
    48961 ttttgatgat tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt
    49021 catctgcatt atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt
    49081 tggccgcaaa tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt
    49141 tcttgactaa gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt
    49201 ggattcctgt atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag
    49261 aaatctgtaa tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc
    49321 agtagtgact gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct
    49381 tgttttctgg atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc
    49441 cttttggaat cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct
    49501 gcccagcata tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt
    49561 ttcctgcatc tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt
    49621 ccactgtatg aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg
    49681 gatagttttt atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg
    49741 tctgataatc aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct
    49801 ctcctgttgc tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag
    49861 tatgatcttg gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc
    49921 gagtaggtct ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc
    49981 cttctacctt gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat
    50041 ctgaagcgta taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt
    50101 caggatcgta ataatatgcc tctaaaccag tattcgtttt tttcatctct acgtccagtt
    50161 tagtaatcga gttcgtggcc ggaaacagat tcccatgacc gtttccgaat atattataag
    50221 aacctgtttc tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga
    50281 cactcccagg agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg
    50341 tccccaatcc aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat
    50401 ccgagtccca gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg
    50461 cctgcccaaa caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt
    50521 gggcattcgt ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt
    50581 ctttggggat tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc
    50641 cgccgttatt cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac
    50701 tagcacttgt gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt
    50761 gcttttttgt cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat
    50821 ccatatcttc actagttctt ggtatttcct ccattgttga catcccttca atgttcacgt
    50881 gtgcattttc ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta
    50941 aaaccggggt actgagcata aggagattca tcattagcgc actgtatttt atacgttttt
    51001 ttaacaagtg tattcctccc gtaacaaatt agaaagcgtt tacttaaagt attacctaat
    51061 ttatttttac tgtcaataaa aaacaaaatt ataataagtg tattttataa aaagaaaaaa
    51121 tataacttaa gttgttgata ataaagagat ttattaacgt aaaaagaata agttttttta
    51181 aaataacgta taaaaaagag cataaaacaa agtcgtttgt tttatgctct tcttttatta
    51241 ttttgtgctt tttattttat caaatcactt tgttttttta taaaatttct gcgcctagtg
    51301 tggactcaaa atgtctcaat gcccattcat gtccaacggg atcgaaactt gccacggcat
    51361 ctttgaaaat atggagtttg tatcctagat tatacgcatc gactgctgta tgcaacacac
    51421 agatatctgt acatacgccg gtcaaataaa tatctgtgat ctggcgttct cgcaaacgga
    51481 tgtctagatc tgttccacta aaagcggaat aatgccgttt gtctatccaa taaacatttt
    51541 cctcttgctc atagtcttgg tataaacttt ttaaagagcc gtacaattcc cgtccacccg
    51601 ttcctatcac attatgcgga ggaaataagc ggttctccgg atgaaaggaa tcttttggat
    51661 catgcgcatc aatggcaaaa acgacaaaat ccttttgatc aataaacttc tttgtatgag
    51721 cagtcagctt tttttcaatt acttgtcctg ctgtcccagt agtcagcttt ccatcctctg
    51781 caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc ctccttatac
    51841 gagatgtttg acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt cttcgataaa
    51901 ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac gtacgatcaa
    51961 aaatgggata ttgaactgac gagctgtttg tccaacagcg gctccttcca tttcgcaagc
    52021 taatgcttca gggaaattcg ttaagatttc tttgatttta tctggcgagt cgacaaatgt
    52081 atcacctgta acgatcaatc cttcttttgc gttcaaattc gttgcttttg ctgctttaac
    52141 catttcactg cgcaaatatg tgcttgcttc ataatataga ggcattcctg gtaattgtcc
    52201 tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa gctactttgt ctgatataac
    52261 gatgtcacct acttgtaagc cttcaccgat tccgccagct gaacctgtat tgatcaccat
    52321 gttcacgccg tattgttgga tcaacagact tgtggtaata gatgctaaga cttttcctat
    52381 accggaacgt acgacgatca cttcgtggtt acctaatgaa cctgaaataa ataaagcgcc
    52441 tgcgcgttcc catgataatg gttcgcttag gttctctctc aaaattttta cttcttcttc
    52501 cattgcgccg ataataccga ttttcatctt tttaattcct tctttctata taaatgcgat
    52561 tgctaaaaaa accacacata acattaggat aacaataata agagatttca tcaaaaaaga
    52621 gttccatttg gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg gtttattctt
    52681 tttgctttct ttacgataaa agctggcaat ctttttttct tcttgctgat aagctgtttc
    52741 tgcttttcgc tgttttttta atgactcgct tgcttgtgct tgttgtcgct tgcgaagttc
    52801 gcttcgcgta ataagcggtc ctttggccat aagccgatcc ctctactttc ctttggtcaa
    52861 tagttcccag tattgaatcg cataaatcgt ctttgcatca caaatcaact gatctttcat
    52921 cgcttgttgc gcctcttcaa gagttagatg atacaactcc agtacttcgt cttcatcttg
    52981 tgctaaagga ttctcgacct tctctacccc ttgtgcatga taaatatgaa ggacttcatt
    53041 tgcaaaacct ggtgaaagat acatcgaagt aagatggctc agcgacttcg cacgatagcc
    53101 agtttcttct tctaattctc tagctgctgt catttcggga ttttgtcctt ctcctggatc
    53161 gatttttcca gctggaatct ccaaaatcac tttttctaaa ggttttcgaa attgtttgac
    53221 aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag gatgaaatac
    53281 cagttctctc ttcgaagttc ctccatctgg caaacgaact tcgtctacag caacatcaat
    53341 aatttttccg ctatagattt ctttgcgact gattgttttt tcttcaaatt gctcattgtt
    53401 cagcatatct tctcctgctt tctttgtaat cataactgct tttttttcat ttttcaattt
    53461 ttctcaaaaa ctccttatta gtttaccata gataaacctt agattttctc taaatataga
    53521 aaatccttct ttagtccgat actctttata gtagtccgta tgctaaaata agtatgtaat
    53581 cgaataacga aaagaattca atactcaacg ataaatgaca tggagggttt attatgataa
    53641 aacgaaattg gccgtggctt ctagcattgg tcttgctatt tctctttgtc cgaaacaata
    53701 gtttttcttt tgttctagga cttttattga taggtgtagt tttagttttg tggggactct
    53761 ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc tgcactgact gacgaacttg
    53821 aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt cgacaaacaa
    53881 tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag acagccaaac
    53941 ttaaagcaat cgatctccgc catgatccag tcaaagcagc gaaagcttta ttcaaagaat
    54001 tggtgaaaga accaaaccga ctgcatgaag caagtcagtt tctttatacg catctgccga
    54061 atctagttga tttgacaaat aagtataatg agatcaatga ccatgagatc aaaaacaaac
    54121 agacctatga aaaactagaa gaaagcgcgc agatcatcga ccagctgtca gctttaatcg
    54181 cacaagatta tcaaaaattc gttgctgagg atctagatga tatcgacgta gagatatctg
    54241 ttgcgaaaca gagcttaaag cgtgataata aatatgaacc agaacaaaag gattaactct
    54301 tttgttcata aaagaagact cggaacattc agatgatgtc tggctgtttc gagtactttt
    54361 tctaaagtag agacattcat gtaagaatcg agaacagatt caacaaggag gaatttttta
    54421 tggatcataa accgactgaa acaaaagatg ttacaccagt taacgataca cttgaagatt
    54481 tattgaacaa cccgttttca actccaacag atacgctgac cacttcacaa caagcggaga
    54541 ttgatcagct ccaagagcaa cagacagctg ctcgtttaat tgacaaacta ccggcggaac
    54601 gccaagaaca agctaaacag ctagcagcaa aaatcgatgc taatgatgca cagtctgtca
    54661 tcagctacgg atcggctgcc caagcaaaat taagtgaatt ctcacaatcg atgttgaatc
    54721 atgtgcaagc acaagatatt ggtcctgtag gagattcctt aactgaactg atgtatcgtc
    54781 tccaagaagc caatcctgac gaactgcgtg ccggagaagg gaacatcttc cagcgtgtct
    54841 tcgggaaggt caaacaatcg atctatgaag tgacagcaaa atatcaaaag attggtgcac
    54901 aaattgacaa gatttcagtg aaattagata aagaaaaaga cggtctgcta aaagataatc
    54961 tgatgttaga acagctttac cagaaaaaca aagactactt tgatgcactg aatatttata
    55021 tcgctgctgg agaattgaaa atggaagaac ttcaaacaac gatcattcca gaagcgatga
    55081 aaagagcaga agaaactggc gatcagatgg atgttcagat tgccaatgat tacacgcaat
    55141 tcctagatcg tctggataaa cgtacgcatg atcttcgctt agctagacag atcacgatcc
    55201 agcaagcacc acaaatccgt ttgatccaaa acacaaatca ggccttggct gaaaagatcc
    55261 aagcatctat cgctacagcc attccgctgt ggaaaaacca agtcgtgatc gcattgacct
    55321 tgcttcgtca aaaagatgca gtaactgctc aacgccaagt ctctgaaaca acaaacgact
    55381 tattgaagaa aaattcagaa atgctgaaaa tctcagccat cgaaacagcg aaagaaaatg
    55441 aacgtggaat cgtggatatc gagacccttc aaaccactca aaatgatttg atcgaaacaa
    55501 tccaagagac attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat gcagaagtag
    55561 agcttggaca catggaagaa gatctgaaac aaaaactgtt ggatttaacc caatagatca
    55621 cctttcgctt gttactaaaa caaacgccca acaacagttt attacaactg ttgatgggcg
    55681 tttttcttat ctttcttcta acttctccat tggagtctat ttctcattca tcttgctgtg
    55741 tccatagcca tagccaaaat aaatgatcag tccaataacc attacgatac cgaacacgat
    55801 ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg agacgattgg
    55861 caatagcgga acgaatggca ctttgaattc tccagctttt ggtttgccaa acatttttct
    55921 caacttcagt aagcctagac taacaagcat caaataggcg agcgccatga tattcgttag
    55981 ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat acagctgcca caccagcggc
    56041 ataagtcgct tttttcggtg tacgatgctt ttgatcgatt tctgtcataa acttaggaag
    56101 taagccatcc ttgctgacag caaacagtaa acgagcaagt gaatacatca tcgagatcgt
    56161 taccgtcagt agcgttaaaa ttgcccctac agcgatcacc gcgcccactg ttccatgtcc
    56221 tacatacctc attgcaaaag ccactgggtc attgactcct agttcagtat acggaacgat
    56281 tcctgtcaag atcagcgtca cgatgatgta aaggacagta gcaatcagta tcgaaccaat
    56341 gattcctctt ggcacatctt tttgcgggtt tttgacttcc tcggctgcca ttgcaacggc
    56401 atcaaatccc aagaaagcaa aaaacacaag agctgcacca tctagcacac cggaaaaacc
    56461 aaaaggcatg aatggctgcc agttatcagg tttaacgaaa aatattccta caatgataaa
    56521 caacgcgatg ataccaaatt tgacatatac catggcatta ttcaaacgta atgctttctt
    56581 ggcttcaagc gacacgatgt aagtgacgaa tatcactacg agcaccgcaa tcaagtcaat
    56641 gtatgtacca ttttccggat tgtacccgcc agttaatgct tgtggaagtt cggcccctaa
    56701 acttttcaaa aaaccttgca tatagccaga ccatccggaa gcaacagagg aaaccgctag
    56761 taaaaattcc ccgatcaaca accaccctgt cagccaggca gcaaattcac caaatacaac
    56821 atacagatag gcatatggcc caccaatcac tggcactcgc gaagcaaatt ctgcgaaact
    56881 tagtccagac aaaatgacaa cgattgcagc taagacaaat gaaagtgaca gtgctggacc
    56941 agcattttga ttggccgcaa cccctgtcac cacaaatatt cccgtaccga tgatcgcacc
    57001 aattccaagc atgatcaaat cagacgtttt tagttctttt ttcatctcac tcgtatgatt
    57061 gagattgatc tctttcttac gaaacaaatc cattgaagtt cctccccatt ttaggttgga
    57121 aaacagcgat taaactgttt tcatataccc taaaaggata ccacctaaaa tgactaaaag
    57181 gcaaccaaca ataacataaa tgagctcttt tttcgttttt ctttcgccaa ggatgaaaat
    57241 cccacctaaa gtagagataa tgatccccat ttgtgaaagt gagaagccaa cagctaaacc
    57301 aagtgatttg actgttagaa gcatgcagat gtttcctaag ccccataata atccacagat
    57361 catgtttttc cacacaaact gatcgacttt aactttacgg aaagcaaaga agcttgcgcc
    57421 taagatcatt ccgatacttt gaggtaagat aattgacatc gcatccaaat tcgcccagtt
    57481 gacgatgatg gtatatacac cataaccaat cgtagagaag atcaatgctc taaaaccctt
    57541 accaaaatca agcattttat tatctgtatc tatttttcct tcgtcatctt gtcgggcagt
    57601 caaatacgca ccgcttacaa gaagagctaa agcaataata ccgtatacat aatctttcgt
    57661 ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta attgaaaacc
    57721 agtagacaat ggtagcccta cagaaacacc catgtacttc attccatgga actgtccatt
    57781 ttgtccaaca ctccaagcta agccggataa aaatccgatc aagaaaatcc aaggggtgat
    57841 tacaggacta acaacgaaaa agacaactaa agaaaacaga aatgcaccga tcgtcattcc
    57901 tagtgtttgt tgattggcat cgccaccaat tttaccactt actaaaccaa tactacccca
    57961 tgccaacata gggactaatg ctattaaaat ttccataacc aatctccttt tatttcacat
    58021 gataagaaac ttatcagcga aaacgttaac aacacaagca ctttttttcg tttctaacga
    58081 ttttctaacg tttttcatta taaaaattta agattgggaa aaataaagtc attgttgtcc
    58141 cttttccttc agttgattca gccgtcaaat ggatacctaa tttttcggcc agattttttg
    58201 ctaaataaag tcctaatcct gttgaatgtg ttttgctaag tcgaccattt ctcccagtaa
    58261 atcccttatc aaagatccgt ttcaagtctt ccgctgggat accgatccct gaatctttaa
    58321 ctgaaaggct gactccttgc gcttcctttt ctatgctcac aatgatgttt ccgtgatccg
    58381 gcgtatattt gatggcatta ctaagcaatt ggttgaagat aaaagcgatc catttagcat
    58441 cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg aatatttttt tggataaaat
    58501 aatttgcctg actgcgtatc acaggctgaa tgattccttt tagtccatat tcttggatga
    58561 ggtagtcccg cgagaaactg tcgagtcttg cataatacaa aacttgttct acgtattcat
    58621 cgatttttga taattcattt tctagtaatg tatacttttg atcgtcaata tcgaactcga
    58681 tcgaacgaac tagcaattta gaagcggaaa gtggcacttt gatttcatgg acccatgagt
    58741 caatataatc tttttggtct tgttgattac tgattgctga ttgcattact tcttggtgtt
    58801 cacggatcag ctgattgata tattcttcta ccagtttttc ttcttctgtc ctcccaccac
    58861 tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc taattttccc caccatcttc
    58921 tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa gacgccctca atcaaagcta
    58981 aataagcaat tgtgctcaaa tcaactttga tgtttggcgc cagccacatc acaaagatcg
    59041 tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca ctgatctttc aaatatttaa
    59101 aaaaattcat cttaaccgct catcctttca gggaacgata tatccctgtc ctacttttgt
    59161 ttcgatatat ccttggatac ctgcctgttc gatttttcgg cgtaaccgat tgatgttgac
    59221 tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac agtgctcgca gcaatttttc
    59281 ccgacttaag atctttccat tgtgcttcat caaaataaat aatagacgat attcattttt
    59341 gctcaaatca atgatctctc cgttgatttc catacttccg ttgtcaacat tcaacgtaat
    59401 gccattgtgg ctcatcattt cactagataa ttctgtgtag ttgtaagaac ggcgaagtaa
    59461 tgcattgatt tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa aatcatctgc
    59521 ccccatgttc atagccatga tcatatccat attcgtattc ctgctggaga taaaaatgat
    59581 cggtactttc gatacttcac gtattttttg acaccaataa tagccatcca aaacgggaag
    59641 attaatatct agtaatacaa gctgtggttc ttctctttca aagtctgaga acacttgatt
    59701 gaaatcggtc gttccaaagg tttcaaattg ccatttctca agttcctcca tgatcaattg
    59761 tcgaatgatc tcttcgtctt cgactaccat gatttttgcc ataaaaaatc cctccatctt
    59821 tcttcttgct actacaatat caaagaagcc cttgtgaaac aagttggctt acctggaaaa
    59881 tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc gtttgtctct
    59941 tccaagcagc ttaaatttat tatgttattc ttaataattg gtctattatc tgttattttt
    60001 ctttcgttgt ttttgtcttt taaattttcg ataacaccaa taaccgaaaa gcgttagcac
    60061 tagcaatata cctagaagga gtataagtaa tcgataaaga tggtattttt ttgtctgttc
    60121 tatctttgaa gagacttctt ctgtaaaggg aactcgtctt cctgtcacta gtaatcggtg
    60181 agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact agatcctgct tttctctaat
    60241 tgctaatgta tttgtttttg ttggaaggac aacaattttc tcaacgactt cataagcgag
    60301 catccgacca tacacttcaa gatagaatcg gtcatcttgc tccatttctt caagatccgt
    60361 aaagagtttt ttctcagcaa taccgctatg ggcggtaatc acggaatgtg tactctctcc
    60421 tccagttgga aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca aaagatcatt
    60481 cgtttcatca aataaaggca agctaacatt gattttcgga atatagatgg ctccgatcat
    60541 atgttgttcg taatattctt ttcctggatt ttggacattt ctaaccgctt gctcaaaagg
    60601 atctttgact tgtcccattc ctgggattac tgatgtatga gcaagcgtct gatttttctt
    60661 ttcatgcact gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa gctgcttttg
    60721 ataattctcg atccttcttt gatccaaata attgctgaga gcatctgcta aaaatggata
    60781 tgtaaaaact gcagctccgg caagaaacat cactgccata aataattgta ataaaagact
    60841 gatttgggtt tgaggtctat tacctatttt ctttttcatt ttcttcacct tcttatttaa
    60901 aaaaactgca gcaaccttta taaaaccgat tgctgcagct tatttttgtt gcttatactt
    60961 cagacttcat tttagattta cggtaccagc tgtacgctcc aatcatcaaa cttattccga
    61021 ttagtaagaa tgccaagagc ccgttcccac cagtagcagg aagtgacccg cgtttcatat
    61081 tcggtactct ttctggccct ggattttcta ctcctacgat ctgaatttct tcattatagc
    61141 ttccataaga gatgataaat tcagtaaagg ctgcctcacc tgttggaagt acataacctt
    61201 ctggcgccat ggtctctttc atttgatagg ttccataatc taacccttga acctcaaagt
    61261 atccatttcc atctgcgaca aattctgttg cttgtccgct tgttgcccac tcaattctat
    61321 ctgctcctga ttcataaaca gctaaaggcg actccccttt ataaaatatt gcgtattcag
    61381 aacggtcttc attccacaat tcgaatcttg catctttaag caattcactg cttgatgcat
    61441 catatttttc aaactttctt ccacctgttg tgactttctc tggcggctct actccttctt
    61501 cataatcaaa ttcatcattt cgtccgattt caataaccgc tgtgttgtta tggaaatcat
    61561 ccgcttctag ttctgtggaa accttcaaat tatacgtgat cgttaaatct cctccacgtg
    61621 catctgctaa tctacctaaa gtatctactt tggctactcc attttcttct gtcaaaatcg
    61681 tcacgacaaa cccgttgctt actacttcta ctatataatc ttgtcctttt gttaaaatcg
    61741 tctcgccggc tcgcacttct atttcctgat cataataagt tagaccaact gtaggcgtat
    61801 ctgtgatttt gtaatttttg ataacagcgc ttccgttttc aaggacagaa tcgatgaaat
    61861 aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga tcaatataag
    61921 aaatcgtttc ttgttctcca gcttcattaa taatcgttac ttgtctaagg tcgctttcct
    61981 ctacattcat ctgtttatct gcttctctga tttcgttttt cggatacaaa tgcacatctg
    62041 tattgtatgt gtctttccat gtagaaccat cccacacgcc atccaccata tcaggcatca
    62101 tcactggcat cataacaacc attggagacg cgattctgga aatatgagct ggcgaataag
    62161 tttctaagaa aagatagact ttatctctag aagaaggtgc ttcttccgtc acttggacgg
    62221 tagagaatac cgcttctcca gcttcattcg ttgtttgttt gtcaatactt gtcagtcgat
    62281 attttaaaaa ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct tcggcagaat
    62341 taagaccgtc ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg taatatactt
    62401 ccgttacgtc aaacaaatca aaatcgactc ctggaatatt ttcttcacca aaatccgtag
    62461 aaaccaatcc gctattcggt cgttcttccg gaacagatga gaaacctttt ttgtgtaatg
    62521 taatcgtcac ttcacttggt ttttgtgcga cttcttcggc tttgactagt tttccgttcc
    62581 cgaaaatccc tattcccgca gtaacgagta acagtacact cattcccgtg acaatcattt
    62641 ttttattcat ttttttctcc ccgttctttt tttattaata aaacagcacc taacaataaa
    62701 agaattccta gtaaagaaat caacgttctt gcttcattcg tttgcgggaa tacggaccat
    62761 tttcctgatt gacctggatt gcttggacca ctcggctctt tcggtttgtc cgttgtttct
    62821 tttacggtct cgttataaac acgtggtgtt gcggattcat aggcagagac tggaactttc
    62881 ccggattcta attcagccat ctcctgtccg ttaactacta catattgtgg ttggcctttt
    62941 gcatccaccc aaaattcagg gatgatgacc tcgattctct tacttgcttc atccatctcg
    63001 taaccttcca caccttttaa ttcttcaaaa taataggtgc cagaaggcaa gaaacgttgt
    63061 cctgtcgtaa caaggccctc tttatccgaa atgaatttgc ttacattttt gtcattcaaa
    63121 ggatcattgt ctgctggttt gatccattga tttttcaagt cattagcagg agccatatct
    63181 aaataatatt tccccccttc tatcatctga tatagagcaa aaacagcacc ttctaatggt
    63241 tttccttttt cagttgttcc tctttgacgt ccatacttga agaagtatgg atctcttaga
    63301 taaccgacat ttttaggata gatatgaatc tcttgcagtt cctcggttga ttctgtcggg
    63361 tgataaattg gcaaaatagc agcaattggg atagctgtct gatcgatatc aacatccaat
    63421 ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg atcttggttt
    63481 ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt atctttccca
    63541 gttgttaccg aagtccctat ttggacaagc ctttcttctg tgattagctg acggatattg
    63601 tttctgttcg tttcagcgat ttgctggacg aattctttag gagtcatgtt ttcagcagct
    63661 tttttttcat gataataatc ggtcatgtcg taaatggcaa atgtcgctcc atttagtggc
    63721 accgtctgtg aaatgatatc tgctgtttcc cctgcttcct cagagatagc caagccatca
    63781 ttttcatggt attcaaattg atcgttataa tcgatatctc gaatcatccg tttatgcaac
    63841 acgaattcca cgacatcttc ccctgattct tctgccgaca tcgcatgtgg aagaaggact
    63901 gctgcaagcg gtagtaaaac aagtaattga agcatcaaac acaacagctt tttcattacc
    63961 ttgctccctc ctttttagat tgtctgacaa acaaaccata ggctgctcct gcaagcgcca
    64021 tgaagaatgc agcaagcagg atatagaata atcgtccgga tcctcctgta gcaggcaacg
    64081 gattttcagg atcgttcccg acactaagct gtaatctgat tcgatttgtc tccaaaagtt
    64141 catattctaa ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga taatacgaaa
    64201 tctcaacttt tagtgtaccc gcttcttttc ctggaactac ccgatcattt tctatgtcag
    64261 gttcttctcg ataactaatt tctaaaataa agtaacctgg aagttttcta tagctgtcag
    64321 gtgacttcac ttccttgatc cgatagaccc cttccaacaa gtctgaagca ttgaataggg
    64381 aagaatcgtt tggatctggt gccaagcctc cctcgatgat ttcatactct cctgcactat
    64441 tttgtttctc aattgaaaat tctgcgcctt caagacgtcg gctattcata ctgtcaattt
    64501 tcaaaagttc caaatcgatt ggcgctagtt catcttctaa ggttacttgt agtacaccat
    64561 cgatgatttc atagccttcc ggcaagggag cagtttcgtc ttcgatgacc gtatcttcaa
    64621 tgataaactt accttcttca ttcagtgcaa actggaacac ttgatcagat agccgatacc
    64681 catttggtgc gacagattcc gagacctcat attcaccaat agacagatgc agaggttggt
    64741 cgtaatttaa atcgacatac ttttctactc ctacggcacg agaatagaag tatccgatcc
    64801 caggcaaacg tttcgattct tctggttcta acggattacc agtgtatgct cgatacagcg
    64861 ggaaggaaga atcccccact ttcctgatat cgaaacctgc accatctaat gtatggcctt
    64921 catggtctaa ttttctaact cggatctccc gataatcaaa cgtattgtaa gcagtgaatg
    64981 ctacccataa acgatcctct tcatctgttg tatacgtgag atattgccaa ttttcttcac
    65041 ctgtttgctt gagttggata gtccctatag cattatcgta aagtcgcaag atccatgtgt
    65101 cattttcatc aggttctttg aaaccttctg ggttctggct ctcaatgatt ttgtattctg
    65161 catagttggt agtttcttca ctatccttat aaacaaatga atctggctct ccgattggat
    65221 gaataacttt ctcaccatcc acgattacat atttcccgtc ttcatctact gaatagaacg
    65281 tgagtctccc tttctcttcc tctacttcgt tcacaccaga aagccctttc gctactggat
    65341 atccgatttc cagtccgtta ccatctgttt cataaagttc aaactctgcg ccattgattg
    65401 gcatattact gccttcaatt agtttattga tattcatgtg gattggcttg aattcatttc
    65461 gcatttccag tttgacatac aactcatcat actctgtgcc ttctatgtta ggctcttgta
    65521 caacagaaag cttgtgatat tctccttcat aataggaatt cggatcttta ccttccggtc
    65581 cgccgactct cgaaccagat gtatattcat ctacaagctc gtagtgacct aacatctcat
    65641 cttcgttggc tgcatatttt ttgatttgga attgatacgt ctcatctact aactgataac
    65701 gtggtggtcc agcgatctct ctgatccaaa atatgtcgct gactgctcca gtttcatctc
    65761 ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt ttacttgttt
    65821 cgattggttc ggcttcccca ctctctggat tttggtcata taatgcaaat tcgactccag
    65881 ccaacggctc gccattttga cccttcttgc tgacttggaa attacggcct ttatgttcgt
    65941 aacgaatgga agaagatggg aaatacatcc gtccagtagt gatatcattc tcataatcct
    66001 ccaggttctg aatataggcc atattgttca ctgtgcaaaa atttccgtct tgagctcccg
    66061 catcaagttt tacttggtac ttgatcctga ccatttcccc ttcacctaaa gaaatcggag
    66121 aaaatttata agcttggttt tcccgtccga catacgttgt cggagtcgcc actacttctg
    66181 gtggggcttg tccatgacgt tcttcatccc atatttctgg ctcttggtac ttcatgccgt
    66241 tttctcctgg atctagatgg taaaactgaa tatctgccga tctgccagct ccaaatggtg
    66301 agacattaaa accagtttca tcataaagtg tggcttgctg gatcgttctc ttgaaggtag
    66361 aagagatatc ctccaaggct gtaacaatgt cattcttgtt gttcgcattg taatatcgcg
    66421 gtgttacgcc atcttcttct aaatcagcaa tatttttcaa tacatttcgt ccaatagcat
    66481 ctagtcgttg tctcccgcta acgtttccat cgattcctaa accaatggag aagatacttg
    66541 gcgggttctc ttgatacttg tttttcagcc aatgatgata agcaactgtg ttgatcgcag
    66601 atgacttttc ttgcgaagta ggactgccat tcgtattgtt attagaagaa ccatcaccaa
    66661 cccagtgagt cgctttatta tctccttctt ttacctctcc ataacgatag tgtacattta
    66721 cttcatcttc tggacggtta aagtcagatg cataggtaac tggatgagta aaccctgcat
    66781 tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta tcttcagcaa
    66841 tcttatcttc catcacagtc cagttgctcc aagctccatt agtgctcgta cgataacttg
    66901 actgaatcgg tgcataactg aaggtcggtg tcccatctcc cacaacgatt aggatttttt
    66961 ctggatttct attttctccg ccattgtctt tatacaatgt ttcatagcca tttttaagcc
    67021 ctagtgtaag cggagttcct ccgattggtg tacgatttaa tgctgtattc tcacttcccg
    67081 tcaaacgatt gatatcattt gtcaatggaa agatgtccga actgatttgc tcatggttat
    67141 tgatagctgt actattatgg taaaaattca ccataccgat tcgaatatcc agactcgggt
    67201 cagagagcag atctttactc atttcgttta ctgcctcaat caacgcagca tttttagttt
    67261 gactattggt cccagcggtt aattcactca tactcgctga cttatctaga acaaaaacga
    67321 tatcgattgg actgatttcc tttttctcgc ccccgatgac atctagatag acattgtaaa
    67381 gggttgttgc atcttcagga tgtagatcag atgctgtgct gcttggcaga acaggttcta
    67441 cccatttttt gatgtacgcc ccgttataat ccaagtaact gttttcaaaa ttccgttcat
    67501 ttccccaaag ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct gcagttgatc
    67561 cattattagt agcatagtcg taatttcgcc agttcgctcc cccgtttgta taatcactat
    67621 catcgatcaa gttctctccg tcatatggcg agcctttgtc tccttgatag cgttcattgc
    67681 tttgtgtcca atttcctaac acttttgtat agtcattcgt tgtaaacttc atctattctt
    67741 tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat cttttctgtt
    67801 tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac ataccattct
    67861 tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga ggatagacct
    67921 gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat tgctaaacgt
    67981 attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc aagggtttct
    68041 tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa tacctcatcc
    68101 tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata gactgactgg
    68161 aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa ttttaaccct
    68221 ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat caacaaaaca
    68281 atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat atccttttta
    68341 gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa attttataac
    68401 gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta cgctttcctc
    68461 gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt cgtacaatta
    68521 atacagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc tcctcctaaa
    68581 atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa acaagcaaat
    68641 aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac tgataaaaag
    68701 gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt gtaaaggaca
    68761 agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat aaaaagcaaa
    68821 ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc tctagtatca
    68881 ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt agagatatta
    68941 ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt ggcgaacttg
    69001 ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct cctttttaag
    69061 aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca agaaactgaa
    69121 acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa ggatcaacgt
    69181 gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa atgcagtaat
    69241 ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga gaagcgcgct
    69301 taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc caccccaata
    69361 gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta aactatcttg
    69421 ctttccataa aaagagaagt tctcacgaaa ctttttccag aatagtgaac cgagcttttt
    69481 ctcttcattt tttttgtaat gataaatcat atacagaact gttcgacttg cagttcctaa
    69541 tgtgaaaaca ggcaagacgc acaggaacca tagtagctgt aaatggataa gacgtggaat
    69601 ccattcaatg atttctaaga aataatcatt ggctttttta ccaatcgatc gattcatcat
    69661 ccttttgaac ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc aaaaaagaac
    69721 agcaaaatcg tcgggatcaa gacaagtgtt gctcctgcca tcagataatt ccattgtgtc
    69781 gttgcttggt tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc ttgatcttgg
    69841 atatataaca gaggacctaa gaaatcattc caagctgcgt tgaaggaatt gatcgcaatg
    69901 gtaatcaagg caggtttcgt caatggaagc atcaaatgac tccaaatata caaatgattc
    69961 gctccgtcga tttcagcagc ttcgatcaat tcattattga tcgataagta aaattgacgc
    70021 atcagaaata tattgaacgc attgccgaag aacgatggaa cgatcagggg caaataagta
    70081 cctacccagc cgatcttgga gaataataca tattgaggga tcatcgttac aaaccccggg
    70141 atcatcatcg tagaaagaac caaagcaaac atcagctttt tcccaggaaa atcaagcttc
    70201 gcaaatccat aagcaataaa agaatttgaa aggacattac cgatcactac tagcacagtg
    70261 atgaataatg tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt atccagatag
    70321 ttttcccata cgattttttc tgggaaaaag gtcggaggat aacgaacgat ttcttccatt
    70381 ggtttcaatg aagtaaacac catccaaagc aatggaatga tcaaaatgat tcctattact
    70441 gtcatgagga cataacttag tatttttttt gtttgccgat tcacactggt ctttttgaaa
    70501 taatccatca tttgccgtca cctccagaat aatagaccca cttaggtgca agcttcaaat
    70561 tgacaaacgt cagaaccaac acgatcagaa acaggatcat tgacatagcc atcgcataac
    70621 ccatatcaaa agctacgaac gccttgttcc acatatgcag attataaaaa agcaaagaat
    70681 ttgcaggtcc gcctgttcca tttttcgtca tgacataagc ttcttgaaaa atttggaaag
    70741 aaccgatcgt agaggtgatc acatcgtaaa aaataatagg agtgattaat ggcaaagtaa
    70801 tacttttgaa ctttccccaa acgcctgctc catcgatttc tgctgattca tataaagatc
    70861 taggaacatt ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa ctccatattt
    70921 tcatcaaaat caacgcaggt ttcgtccatt gtggatcaaa cagccaagct ggtccaggga
    70981 tatggaacca gcccagaaat gtgttgatca atcctgcaga tggagaaagc agctgcatcc
    71041 ataagatgta gactgctact cctgataaga ctgccggtaa atagaaagct gtacggaata
    71101 cactgattcc tttgattttt tgattgagta ctgtggctaa aaacacactg aaaatcgtcg
    71161 tcagcggtac attgaagatg acgaaataaa cggtgttgta taacgatttc caaaataaat
    71221 catcgtgaac gaacattctt ttgaaatttg ctagaccaat gaaattcatc ttggatgtca
    71281 aattataatc ggtgaaacta ccaataactg aaaaaagcat aggccctagc ataaatacca
    71341 agaacccgat aataaaaggc gagataaata aataggccca tcttgcttct tttttctttc
    71401 ggatagataa acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc aaaaatggat
    71461 tattgatttt gcttgactaa gttttctact gctttttgtg catctgccaa tccttctttt
    71521 ggtgattttg ttcctaaaag aatctggtca atctgttcat tcactaatgt cgtgtaatcc
    71581 ggagcatcta aaggaactgg tgtgatcacc gtatttttaa agttttcgtc cgccatttga
    71641 tagatcattt ttcctttatc cgttaggttg tcattattca ctaaattctc attggctgtc
    71701 ttgctcgcca tgatatcaaa acttttttcg ccgaattttt cttgtacttc tggagaagaa
    71761 agatatttga tgaattcata agaggcctca ggatcttttg ctccgtatgg tacttccaag
    71821 acgaatccgc caccccacga ccaatggcct gaaccttctt ctttttctgg gagctgcatc
    71881 acgccaaaat caaaatcatc cggtgcattt tccatcaaac tagagtaata attgatattt
    71941 tgggcacgca tggctactaa tccggaaata aatggatcag atacaccaga cccaaattcg
    72001 gcttctaatt tattgatcgt atttttccca taataatctt gccagtcttg gatccactcc
    72061 aaggcttcca ctttattttt agtatcaatc ttgacttttt catctttgtc aaaccaacta
    72121 gtcccgttat ctgcgtttag cgcccataca tcagccccta aattccataa tggataaaaa
    72181 ccgatgcgtg taaattcttt tccttctttt ttatctagtt tacgtgctgt ttcttctaat
    72241 tcatcccaag ttgtcggtag atcttgttca ctgattccag cttctttaaa taacttttta
    72301 ttataaaaaa tgacttgtgt atctgtattg aatgggatcg cataaggatc accttcatat
    72361 tctactgtat cccaaagctg cggataaaaa tccttagaag tgtctttttc tacatatttg
    72421 gagagattag ttgcttgctg tgcttctgct ctttgggcaa cggaatttat gtcctgtaca
    72481 ataacatcgg gtgcatttcc agctgttatt gcagataaag atttagtcca gatgtcaccc
    72541 catggctgat acttataatt tacatggatc tcgttttgtg attgattgaa atcctcaatg
    72601 atttcttcga tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa atcaatattt
    72661 tttcttccat cacttgtttt ttcagaagaa tttgctgcac ttgaactggc atcgcttgca
    72721 ttacttgatc cgcatcctcc taataaaaac aatgctgaac ttgccagcaa ccctgtaaac
    72781 aataattttt tcatatttta cctccaaatt ttaatgtaac cgatgccggt tttaatataa
    72841 cgatatcatt ttgttctgaa aataacaatt tataaggtat gattctaaaa aaattattaa
    72901 tgataccaat actttatata attcgcgagc gctttctttg aattttttaa tctttcgtag
    72961 cagaatgaga atgtattaaa aatagattag gaggaatttt gatgtttaga caccagaaag
    73021 aattgcagtt tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg
    73081 agctgatcgg cggccaatat ggcgagatga gtgtagctat gcagtacctg ttccaaggct
    73141 ggagctgccg aggagaagaa aaatataaag atatgctgat ggacattgca acagaagaaa
    73201 tcggccacgt ggaaatgttg gcgacaatgg ttgctcgttt attagagggt gcgcctgttg
    73261 aagatcaaga agcagcgatg caaaaagatc caacaatcgg tgccattatc tctggaatga
    73321 atccacagca cgcgatcgta gctggcttag gacctcgtcc tgctgacagc gtgggcaatc
    73381 catggagcgg tgcctatatc attgcgagtg gcaacttgtt agcagacttt agagctaatt
    73441 taaatgccga atcacaagga agacttcaag tagcacgtat ttacgaaatg atcgatgatc
    73501 gtggcgtaaa agatatgctg tctgttctcc ttgcaagaga tagctatcat caaaatctat
    73561 gggaatgtgc agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc ccaagtactt
    73621 tcccgcgtga caaagaacga aaagacattg cttatgactt ctataacttc tcagagggag
    73681 accaaagtag tgaaggttct tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc
    73741 aatggttgaa agaacctaag atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa
    73801 aaatgtatgg gacacctcca ttcaagaaat aaatatctac ccgtagaaac acccgttttt
    73861 tgttccacac gctttgtgag caaaactgac taaagtcatt aatcataacc acccttcaaa
    73921 agggtggttt tctctagagc tataagctca aatcaccggc cagcgcctaa agacgctggc
    73981 tttcatattt tatgttcaag ccatattgcc tttgccagtt ttgcccacct cttaaaaggt
    74041 ttatgtacta ctccttagcc cttaaaagga tcgtcttact ctcgtacact cagcttatct
    74101 aacgcactat catgtttttc ttgttcttga atgtactttt tgatggtcgc ttcattttgt
    74161 cctacttttg tcacatagta tccttccacc caaaagtgtc gatacccaaa tttatatttt
    74221 agatttgcac aatctcttga tgatctcctg aatattggct cgatattgat tataaattat
    74281 ttttcttcta tactttggtg tgaatacaat gtggtattta cacatctact ttgtacgggc
    74341 taaactattt ccctttattg ctccacccgc atagcaagtg gttttgtatt tcaatcgctc
    74401 ggcgcgctca attaggtcta aagacaataa atctaaaaac ccgctgcttc actgacagaa
    74461 acaacgggtt ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat ctattttatt
    74521 tttttgattt tttataaatg gaaaatgctt caagaagtcc aagaaataaa gccgtataaa
    74581 aacaagaacc tatgaaatct ttatttatta gatattcaac agaaatcccg ataacactag
    74641 ccaacaatat atttatcaga agtgtaaaat aaggatgctt tttatagaat agaactagtg
    74701 ttgttttcat agactctcct ttcttcatat ttccaattaa tcacaaattc acggcattac
    74761 tagaaaaatt aaaggggcgc agaagtggaa aaatactctt cgactttccc tacaaaccag
    74821 gccatcttgt gtttaataac tataccaaat ctaaggtacc tctaaatcta aattccattt
    74881 gtggcggtga cctccaattt ttaactcttc tatctcccat ccagtataca taaccttgat
    74941 acttcgacca cttatatatc gaacacacaa atacctatcc attgcaggag tactacctaa
    75001 cttagttgct acttgcatct aaataacagc tgaaaagata ggacttactc ttagtaaagt
    75061 atctgaacta ttaattttta aactatcatt tttatcctca actacatgca catctgttgc
    75121 aacttcactt tctgtctcat ccagataaat gattaaggaa tcgggaattg caatatcttc
    75181 agctgacgct ggaatagttg agctaaatta gtcatcatat ctttattata aaataaccaa
    75241 cagcaaaaaa tacaatgaaa aacaaacttg gaactaatgt atcattaata aatgttgaaa
    75301 aattcagcaa ctcattactg tatgatttta gcagcccaac caacatatac cctataaaag
    75361 ctaataagat ggttaggaat cctttagaat ttttactcat tcatagacac ttccttaaat
    75421 aacttttatt atagaaggta ttgtaaataa taatattgac aaaaagtgac tcaaaataaa
    75481 aaaaaactta cattatactg gaatgaactg tattgatagt gtacctaaaa gctctactga
    75541 cataagatcg tgtaatcggt aaagtaattt tattaattat acgggatgta atcaattaga
    75601 gaataaacta atcataaaag gtacttttac attcataatt gtcgctttga gattctactt
    75661 tggttcacta tctgacccaa ttgcacattt tcgatcatta caagtattgg tgtcgttaga
    75721 acaactaaat aaaaactagc ggtagatttt tcagaatcta tgctaatttc tgtatggatg
    75781 ttccagtgat ggcaaatttc tcttttcatt gtttttcttg tcgcatgata tgcctttttg
    75841 tgttattcag ttaaactata gaaattcttt cctagacaga tcttgatccc aaattttacg
    75901 tttttgagca tcgatatagt ttaaaatgac attactcata tctaaagagt ttagattttt
    75961 taggactaaa actgtcagtt gttctttttc ttctttctgt taaagtattg tcgcgacttt
    76021 tcgtatacgt taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa aacgaatgac
    76081 ttgaggaaat cacctcaatc attcgtttaa aatgctatat attctttagt ttaagatacg
    76141 gaaattaatg ccatcgacca cactagtaga atgaacgaca tttacttggc ctttttttaa
    76201 tttcgttatg tttagcatat aaaaatatta tagagtttac ttacaatgct taaaacatat
    76261 actgtataat ctgatcaatt ttagccatgt cttgcaatgg taagttttct atttttttga
    76321 gttttcgttc cttaaaatca agagatttta attgtgtaat aattacttgt ccttttatat
    76381 ctagctcttc aggtaatgag taacgtgtcg gtaaattctt tatagtggaa gtaattggac
    76441 atatgaccga aaacattgtt ttacggttaa attcataacg agagacgact agtcctggtc
    76501 gtcttttttg aatttctttt cctacggagg gatcaaaatc aatccataca atatcacctt
    76561 ttttaggaat ataaattctt tcttctgaca ctataaaatt tctctccctt caggagttaa
    76621 atcttcccat tcgtctttct cataatactc ggcctcttcc ccaccactaa atggatcttc
    76681 aatttttgga actaacgtaa ttgttccatc atcagaatac acaacgatat attcttggtt
    76741 ttctgaaggt ttctttccgt tatcagaagg taaagttacc actacagaac ttccttgtaa
    76801 tctagatttt gtaacaagca ttatcatcac tcccttaata aaagtatact atataacact
    76861 aagtaacgca aaattcccct ttgtaaacta tctagaaaat tgttttgttt aaagtatatc
    76921 ttattggata taaatagaaa taaattgtag ccagttcatt ttttctttaa ctaaaaaaat
    76981 aatccaagaa acattgaacc tatggatcca aaagctaccc aaatactata gctaaccccc
    77041 cgctaccttc aattttgcag ataaaacgct ttgggagaaa atttcaaaga caacaggcca
    77101 tcctatcatg cccgattata aacaaaaagc tggctattcc ttttgctctg acaaatttca
    77161 attgggaaag ttcacgaaac tagcaggtga agaagtttca actgttcgga tcaaagaatg
    77221 cccgcttcaa atagaaacat tggttcaacg aatttcaact agacaagact ttgctattgt
    77281 agaacgtgag atcgtagcta tttttgtaga agaagggatt ttacatgatc caactcatat
    77341 caatgtggat aaatggcaac ctcttatcta taaattcaga gaatatacaa ctgccaacca
    77401 gtcgttaact ttgaatttta gattccaaga attcaaagag tcataatgat aaacatcgtt
    77461 aggtataaat aaaaaagact cgcagcacga gtaaaaaaca aatagaagct atacattaga
    77521 aaggtcgact gtgaccctat agatgcagta tatgcagctt atgagcattt cttctgttct
    77581 ctttgttttt gggatctgtg ctgaagtctt tttcgttttt tgccgctctt tctttgaaaa
    77641 atcgattatg ttataccttc tccattacta attcaggcat ctgctgagta atgatttttc
    77701 gcgcaaaaga aatatctgtt acccaaggtt cgatttgttc ttcagtcaag acaagcggca
    77761 ttcggtcatg gattggtgcg actgtgcggt taggttcagt agtcattatg attgattctg
    77821 ccattttttc atcctgatgg ctacgataaa aaccgccaat atacactatt ttttccttat
    77881 ttgaaaacat aaatttgtct ttttcttcat tccactcatt gggaaaacac aacgattttg
    77941 caaaaatggt tgatgaaagg tctttttttc ttctactgtc tctgcacggg cattaatcat
    78001 caattgtcct tttttaaatc cggtaaatcc ccacttcatg atttccggag tgaggatgtt
    78061 ttcttcctct tttcttaacg tcacaacaag atttgacgga aaaacttctc cagctgctaa
    78121 ttctgctgcc tgcttcggtt gtttcgtctg ggcttctcga taataattct gaaggagctc
    78181 tgactctaga tcaaaaaaat aacgaccaca catcctaatc cctcccaatc tttttttcta
    78241 tcatacactg caacaagaag ttcgcaccaa caaaacgctt tcaatttttg tagaactaaa
    78301 aaagttgtga caagtgacaa actctccagt gaatggtatt ctcctgccaa ctcctcggtc
    78361 acaagtcaca atattcaaca aacatgagaa gctgcttttt gaaattgttc cttgtgactc
    78421 ggagtgaaac ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc agtttctcgg
    78481 tattaagcca aatttatgca aaaatgtaga aagctatttt cacaaaattt ttcttaatac
    78541 tcgaaactaa gcgacttttt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct
    78601 gcggtaataa gcccaaccaa acgaaaaata tgagcagcta tttttatttg gctgttctta
    78661 ttacttgatg cagggcagct ttttcacaac ctctccacta aacgatgttc aatcagctaa
    78721 ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc
    78781 taatactcag gtcaaagcgc tgatttcaca acctctaata cacggtgttc cagaagtagc
    78841 ttcttcgaaa aataagccga aatttcacaa aaatttgaga agcaattttc gtaaattcct
    78901 tcttatttct tgaagctgac cacttctgtc acaacctcta attattaaag aaccttttgc
    78961 gaagttaaca atctttcttt gaccaattga aaattctgcc taagtagtga tagatcctgt
    79021 gtgactttca acaataagat acttccctgg atttcagcaa tcaacgcttt ggcttgacgg
    79081 tctgcttctt catcggacag tttttcttca gaaagtgcca ggatattttg tttcgtatac
    79141 ttgacccatt gattgactaa ttctagtagc aacagacggt attcttcatc cactgtactc
    79201 aactcaataa tcaaattacc tacaggacag ccatgataag tgatctgtgt ctcatgatca
    79261 gcgaaaatcc agtccaacat ttcttctaat gcttcttctg gctgttttcc agcatttaag
    79321 atgtcttcga acaattctgt ctgccatacg tccatatgcg catggatcac cgctagacaa
    79381 acttcttttt ttgaagaaaa gtaataataa aattgacctt ttcctgtatc agaagctgct
    79441 agaatatctc ggattgacgt ttcatgatag ccttttttat aaataagatc tttggtcgct
    79501 tccaagatct tttcctttgt tttcaatgat attctccttt ttcatttctc atagtcctat
    79561 attatacagt aaattcatca ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt
    79621 atctgacaca gccctcacta taaaactgtt ctcatatagc tagatgttca ttgattcaag
    79681 aactgcgagg acaaaagcaa ttcctatctt atgatagttg ctctaatact tcctctgttg
    79741 tcatcacttg atctgcaata aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc
    79801 caggagcacc aattgcatct gtcgctacca caacattgaa tccactctct accaattcac
    79861 gcatatggga atcgctacac aagtttccgt tcattccacc aagaattact gtgtcgattc
    79921 cattttttct caattggagc gccaaatcat tgctttctgg tccaaagatt ttatgaggag
    79981 agctgatgat cgtattttca tccaaataag gtttcaattc ttcgataaaa tcggctcctg
    80041 aaccttcttc cactgattca tattgacttt ttctagcaaa catctgctgc tcaagcatca
    80101 tatgttctcc tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa taatgaggag
    80161 aaataaagag tttgtatcct ttttcttttg cttgttttac catttcaatc atattttcga
    80221 tcgtattgta tttttctaag atatcttttg tcaaaccaaa gccaccgcct gctggtttca
    80281 agaactcgac ttgcgggtca gtgagaacta ctgctgtatt tttattattg aacatggtgg
    80341 attctccatt cgttatttat tttaatacat catttagagc ttcactcatt gtcggatgag
    80401 aatagatttg atctctcaat aacgtataag gaagttttcc attcatagct agcgaaatca
    80461 agttgatgac ttcatgagaa tcttccgcat agatacttgc ccctagaatc aagtcagttt
    80521 cagggtcgac taaaactttg aatacacctt taggatcttc taatacttgt gctttaggga
    80581 caccgcttgt catatacttg aataatttgt aattgacgcc ttgtgctttg gcttgttttt
    80641 ctgttaaacc tacattggat aaagtcggag tgataaatac actgtaaggc acagctttcc
    80701 ggttattcgt tgttcgttta ttctcgccct tcaactgatc cataatgatt cgataatcat
    80761 ctagagagat ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt
    80821 ctgcatctgt acgaaggtat tcatccacag cgattgctcc gcgatctgtt agtttaacat
    80881 ctgtattttc taatccaagt gatgctgtac ttggttttct tccagttgca gccaaaactt
    80941 ttgacgcttg gattgttact tcttggccat cttctgtaaa ggtgacggca gctgttgatt
    81001 cttggtctgc tacttgatct acagatacac ctagatggaa ttcgattccc gcatttgtca
    81061 tgtcttctaa aatcatttgc gcgatatctt catcttcacg tggaagaaat tcagaatggg
    81121 catcaagaac gacaacttta gatccgtatt cattgaacat tgatgcaaat tccaagccaa
    81181 tatatccagc cccgatgatc actaattttt ccggtaattg ttcctgatcc atcgcttgcg
    81241 tagaatcaat caagtagcga cttgtattca atcctttgat tggtaaaatg attggttcag
    81301 aaccagtatt gatgaaaatc cgttcgcctt caacaatcac tttttcacca ttattcgtca
    81361 cttcgatttg atggttagaa agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct
    81421 catcgctgat catatgataa tttttggcgc gaagcatgcc cgtcaatttt tctttccgag
    81481 caacagcctc tgtaaagtcg attcctcttt ctccattgaa aatcaatgat ttagaaggaa
    81541 tacagccgat gttgatacat gttccgccat acatacgtgt tgacttttca acgactaaaa
    81601 ccgattcacc ttttgaagct aacgccttcg ctaaagtctt accgcccttt ccaaaaccga
    81661 tcacaatatt ttgatatttt tccatcattt ttccctcgct tcttttttac ctaccgattg
    81721 gtacaaaaat atgataaccg ataattgtct attctccaaa tcatctgctt tatttgtcaa
    81781 aaaaaaccag acaaaaagcg gtcctttcac gtttttagtc tggttcgatt tcctttattc
    81841 ttctaaacaa tcgttacttc tacatcgata tttcctctag ttgctttgga gtaagggcag
    81901 aattcatgcg catcttctgc aattttttgg gcttcttctt cgctgatgcc atcgatatgc
    81961 acttctaata ctacaccgat ctgatagccg ccatcatcta aattataaag agagacacgt
    82021 gcttttactg tggactctgc tgtcattcct gcttctttga tcatatgttg taccgcccca
    82081 ttgaaacaag aagcataacc tgctgcaaat aattgttctg gatttgttcc ttctgcatgg
    82141 attcctggag gagtgatttt catatgcatc gagccatttg gtgcctcgac ttctccattg
    82201 cgcccgccat ggttgatcat tgctgtttcg tatgcttttt tcattgtact gctcctttcg
    82261 attgaccatt tgctacttgg ctataattat agtgtatgac aagtaaggcg ctttctacaa
    82321 aaattctgct tattcgaata ccagaatgcc gtcttctact atttttccaa aaaacaaaaa
    82381 aatactactc gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa tcttttctac
    82441 ataatctttt atatgattga ttttaagata catatatacc agaaagttga ccccataaac
    82501 caatactgtt aaaaaaataa ccatattcgt taccattttt tcctcctttt gctggtctcc
    82561 ctaccagcac tcgatttaac cataccactt tttttgccgt ccaagcaact agcctttcaa
    82621 aaagactggt ttattctgct gttaatgatt caagatcaga aaaatgtccg aataattttg
    82681 ctaattttac taacgccaac ttgttctttc cgaattcatc attttctatc tgtaatacta
    82741 gtaacggctc atgtaagctt aaacggatca aaaaccagcc gtttccgtat ggctcttcta
    82801 gatcatatcg aataccttct tcattttccg ggtcgaagtt catccctttt tcttcttcca
    82861 acagtcgctt catttcttct aatatcttgt ttccttgttc gcgtggttca tcgctgaaca
    82921 attttaatcg gatttcttgt acttctacgg gctgtttcaa ctctttgatt tgttcatcta
    82981 atgtgatacc ttttcttttt aattctggca aaagcatcag gatctttgcg atgacatatg
    83041 caccatcatc cagaaaatag ttttccttga atgcagcgtg tccgcttgtt tcgatggcta
    83101 gctgtgtatc tttcccaaga cggttaagtt ctaatgcttt attgattaca tttcgatagc
    83161 cggaaatata acgaacttgg atgcctcctt tttcttcaat gaatctttgt agatgagaag
    83221 aagtagggga attcgtcacg attcttgttc ctggatgctc ttttaatacg attgtactta
    83281 atactgcgat caaattattt cgattgatca ctgttccaga agcactgaca actgcagaac
    83341 gatccacatc tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa acagcctgct
    83401 tgatactttc catcgcttct ttattatcag gatttgggat atgattagga aatcggccat
    83461 ctggttccaa aaattgggaa cctgttgaat ccgcacctaa gctattcaat actttttcag
    83521 caaagaatcc accagcacca tttccggcat caacaatgat tttccaacca tttagtggtt
    83581 tgctttctag tgttccaatc ccctttttaa tttttgtgac taaatcttgc gcataaggtg
    83641 tcaaaaggtc tgctttttct acgcttccag tttgttcgct ttttattttt tgctgctgtg
    83701 ataggataaa agcaatatct tctttttctg ctcctccttc tgaggtaaag aattttattc
    83761 cattataata atagggaaga tggctagcag tcagcataac cgcagcatcg cacgagaact
    83821 gttcaaattg agtggacata aacatagcag gcgtagtagc taattcgaaa tcgatgacat
    83881 gtatcccttg ttctttcaga ctttggatca acgcctcttt cagtgctggt ccgcttatcc
    83941 tactgtcatg accaatccca atcgtccatt ttttatttgg atcggttgat ttcttctttt
    84001 tctttatcca gtttgctagt ccccagccga tcttttttac catgtctgtc gtcaagttta
    84061 cttcatatcc ttcaactggt aatgcgattc ctcgaatatc cgatccattt tgcagcgctt
    84121 tcatatcttt catataaaag tcctcctcat ttattccctc attttttcca gcttttctgc
    84181 aaatcgctgt gcttcttctt ctgagcggca aataataatg aatgtatcta caccggccat
    84241 cgttccgaca acttcagggt aagccacttc atctagccaa ttcgttacca catcggcacc
    84301 atttcgttca gtcaatacga taaccatgaa ctgaacagac tggatacgca aaacctcgcg
    84361 tctaattgct gtacgcaaac gttcttcatt taaagaaaca gatggctggt taaataatgt
    84421 atagcgtact attttgtttt cattttgact ttttactaac ttcatttctc gaatgtctcg
    84481 agaaatcgtt gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc
    84541 ctgtgtccca ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt
    84601 tttcatatta gacacctctc aatgttgatt atagcaaaag ataagtaata tttcttcata
    84661 ttttggtatt ttttactttt attttttgtt ttcattcagg ttgctaacct ttttctattt
    84721 taacacgcaa aatcgtcttc attttttcag gtgctgattt tcttggatcg ctgatgtaaa
    84781 tctctttgtg ttctttagaa gctctttcat agccttcttt tgcgatgaat gcttctaatt
    84841 tctcaaacgt tgctggttct tcggcatagg gcccgacgtg taagatttgg gcacaaagac
    84901 cttcttccat ctttttgaat actacttgtt ctttcaagtc ttccggaagt ttgctagaac
    84961 gctgaatggc ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg atcatcaatt
    85021 gataagaaaa atgttctttt ttcatcactg gttcatgcaa atacttttct tgcagtcccc
    85081 attgtccttc cagtggatag acagtataca tctgataatc aggaatcagc caattttttt
    85141 taggcgacat gcgtattgca tagctgactg catatagaca ggctactctt cgtttaaagt
    85201 cttcctgatt cgggtcgccg atccctctga tgctaaagaa tgatttttta ggaacctcta
    85261 gtatttgcgg gctttttttc atactatagc tcttgtcttt acgccattca attttttcca
    85321 tttttcttcc tccgcgaaat tccatttagt tatttattat catacctctt tttgagtgac
    85381 ttggctaatc gtgttgacac tatttttcag tttgtgctag aataagtgaa gtaaataaat
    85441 cgtacagata acacgtttcg gcgtgtcgag agagaggcgg tttctatttt tataatagaa
    85501 atcactctct ttttttacga aattttttag aggtgatgta aatgacaaaa caaaaacagc
    85561 tgcttttagt acctgcagta attgcaacag ggatgatgtc ttttgcgggc gtattgatcg
    85621 agacggccat gaatgtaact ttcccaactc ttatcagaca gtttgattta acgactgcac
    85681 aagtccaatg ggtaacaacg atttatcttt tgatgatttc gatcattgtt ccgctgtcta
    85741 cttatttgaa tcgcaatttt agtctcaaaa aactcttttt agcttcaaat ctgcttttct
    85801 tggcaggtat aatgatcgat ttcttctctc ctaccttcat ggtcctattg tttggtcgat
    85861 tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat gttccatatt atcttgacat
    85921 ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg tactttgaca acggccattg
    85981 ctccagcaat tggccccact tatggaggca ttatgacttc acattttaca tggaatcata
    86041 tcttcctgtt tcttgtgccc gttttgattc tttctttgat tatcggctgg tttgctattc
    86101 ccgagatggc agtacaaaaa agtggttatt tggattggat aagcgtttta ggaatttgtc
    86161 ttttgtttag tggaagtcta acatttttga gtacgttggg aacagtttcc agctggattg
    86221 ctttaatcat cggcggtatt ggctggttcc ttttttacta tcgaagtaaa aaagtggagc
    86281 atccactgat ccgactgtct attctttcaa ataaaacatt ccgcttgttt ttgattggct
    86341 tcttagttta tcagttttta ttacttggtg tatcttttgt cttgccgaat ttccttcaga
    86401 tcgttcaagg aagtagtcct tttgtcgctg gattagcgat gcttcccggc gcagcggttg
    86461 gtgctttgct ttctcctttt tccgggaaaa tgctggatca atatggtccg aagaagccaa
    86521 tttttgctgg gctgattctt tctttgattg gttggctagc attattccta ctcataggac
    86581 acgcttcagt gggtgtattg attgcttgtc atgtgtttta tatgatcggt atcggattat
    86641 cttacagcaa tatgatgacc accggaatga atgcactgaa tgaagaacta caaggagacg
    86701 ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc tgtggctact tcattagtag
    86761 cggtcattat caattacgtc cagcatcata cttcccataa ctatgaagtg tctactacat
    86821 taggatcaaa agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat
    86881 tcgcctatta tctgttcttt gctaaaaaag cgtagattcc atatacggca ggtgttgcat
    86941 ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta tggaaaaaat
    87001 tgccattatc ggtggcggga tcattggtat gaccctagcc agttacttag atacatcaaa
    87061 attcaatgtt gctttatttg atgaagggac aggacaggca actaaagcta gcgctgggat
    87121 tatctcccct tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg
    87181 cgctgctttt ttccctaaac ttataaaaga tttccaactt gatcaaacga tttacgcaca
    87241 atcagggaca cttttgcttc gacctgaaaa agatttagct gaattggctg ttcttgccga
    87301 gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa tggctttcac ctgaacagac
    87361 atctcaagca cttccgttat tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg
    87421 tctggatgga aaagcatatt tagaacatct tggtcagcgt ttagcacaaa aacaaatgga
    87481 gcagatccag gcaaaagtca ctttgcataa gaagagcgat tcttggctca tcaagggacc
    87541 gtttggagaa tacacagctg atcgtgtaat tttgacacct ggcccggcac ttaagccttt
    87601 attacaagaa ttaggctatg ctgcagatat acgtccgcaa aaagggcagc tcttagcatt
    87661 tcagacatct tataagatga gtcaagactg gcctgttgct atgcttgacg gagaagctga
    87721 tttcattcct ttcatggatg gaaagatcct tttaggtgct acccatgaaa acgatcaagg
    87781 ctgggatttg gctcctacta gcgaagctta taagggattg actaagagta cagaacagtt
    87841 cttgactgat ccagatcaga taaaaaactg gccatacgag ttccgtgtag gtacccgtgc
    87901 ttatacgtca gatttttccc catttttcgg cgtactgcca gatgatccaa gcttactggc
    87961 tgctagcggt ctaggctctt ctggcttgac cacaggtcct tatatcggct atctattagc
    88021 caacttctta aatactggtc attggcctac ggaagattat caaaaggaca tctccaccta
    88081 tattacgaaa aatccatcat agaaaaacag ctttttcaag taaggatccc gagcgatatt
    88141 gcgcatggat tacttcttga aaaagctgtt attttagttc aatttctgaa tcaaattctc
    88201 caaactttct tttgcttcat ctggcaagag atcttttcct atctgagctt caatgaatcg
    88261 taaacgaata tcaagtcgtt gtttcaccag atttttatag gacgtatcct caaaagaaac
    88321 aggaaaatct ggtataggta aatagtggat gtcttcaaat ggaccaaacg acttgaattc
    88381 tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt tgattttttt
    88441 atcatcgaaa tatccagtat tcaggacata gcaggctgtt tgctgtttca aaaacaactc
    88501 tcgaaaagct tgatagtctt ccctaagagg atagacacgg aaaggattag caaatggttc
    88561 aatgactagc tcatctagct gtctttttgt agtgatattt tccgcgtctg atcgttttgt
    88621 tgctaatgtt gcaccaaaag acgctgctaa aactgggtca ttgatcttga taattggcgg
    88681 aagcgaatca tctttcatga tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac
    88741 tcggtcgggt gtcgcataac gtgatttgac tgtccgccca tttccgtttc gtatatctcc
    88801 tgttactagg actttttctc ctttacttgt acatgtcacg cccacattct gacaagtaag
    88861 gaaagaagaa atggccggat catcagacgg atagtcttgt gttttatcaa agtaagaagg
    88921 ttccaaggca gtagcaaaac cattttttcg agaaataacg aaagcatcgt catgcaagat
    88981 cgaaacagag tgaccttccg tatgttttgc taaggtaatc gttgattttc cagaaccgga
    89041 caacccaaat acagccatcg tataggtctg gtcattacta gcatattgtt tcatcccacc
    89101 gtggcaggca ataaagccat tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt
    89161 ttttaattct ccaaagtaac gtaatcctag cacaaccgct gtattatgga gagcatcaaa
    89221 caaaatgagt ccatttggaa atgtttcatg tgtccattcg ggatcacaaa agatataaag
    89281 atctccctca tcaaaggaaa cagacttttg ataagtctct aagatcttcg aattcgctgg
    89341 ctgaaaattc agcaaataag aatacaaatt gttctcaaat ccttctggaa tcagcaaatg
    89401 actttgcaca gaaaattctt cagataggcc aacgattact tttgtatggt aaaactggcg
    89461 cttgcgactt tgatacacag cttctcttaa aattttctcg tatttgcttt gttccttgtc
    89521 taagtcctca aagatccgcc gagcacttgc tgttcttccc acaatgcttc catcattgaa
    89581 tactagtgtc ctaacatcag ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc
    89641 tgtgatgatc gttcctggac tcccttttgc tagttgataa gctgtcttcc tatcaaaaac
    89701 ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac tggataacag
    89761 tggatttcca cttgtgattt cgtttaattc gagactctct tttgtactca tggctcctcc
    89821 tcattcccta aacaaaaaaa cgttttcttt attatacatt attcgagttt ttatttgtac
    89881 tgctgcgctg tgggaagcaa acgagttatt tttcacacaa aaaaaccgag aacttgaata
    89941 aacaagtttc tcggtttcat cattttcctt ttatcggctt agtaccagcc gtttgctaac
    90001 cagaatgttt tagcagcatc ccatgaacca taacgagatg ttacatattg ttctgctaca
    90061 cgttcttgat tggcagctga atagtcgccg tttaagtatg aagcatctaa ttgataacgg
    90121 ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg attctttttg tgcgatccat
    90181 tcttttgcag agcttgaagt tggcgctgtt gcagcagctg gggcagcagg agctacttca
    90241 actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct
    90301 gtattttctg ttgttttgtt ttctgttgtt gctgaagaat catttgaagt tgggattgtt
    90361 aattgttcac caacataaat gcggttgatg tttgcgatcg aatttttttc agcaattgca
    90421 tcgatcattg agttgtctcc tgcaaatttt tgtgagatct tagataatga atcacctgat
    90481 tttactgtat aaacttcatc agcgtgagca tttgtagttc ctacaaacat tgcagtagca
    90541 ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg aattcatatt aaactccttt
    90601 ttttctccgt tttttattct ttcgacgcta ttaactttat catttagaaa tatttcatag
    90661 gtaaaagaaa catgacattt aatgacaaaa taacgaatta tttaatattt gtaacattta
    90721 aacaaatatt tttttgatac aaaaccataa aagccttgtt gtataagcaa agtaatcgtt
    90781 tttctatgtt ttttttattt ttgaatgaaa aacgcagatt ctgtaacatt cactgcaata
    90841 atccataaaa aaaagcaaaa aaatttttga tttttatcaa attctcttaa aaaaatgtaa
    90901 aaaatacaaa aaaaccagta attgttacaa caattactgg acaaaaactt tgaataatgt
    90961 taactatttt tttattttaa ctttctccgc aataatttct gggcatgttc caattcgttt
    91021 ataacgactt cttctgtttc tttagctaat atttcatcta atacatcaag ccatttttcc
    91081 ggttcttttg ttcctagacg tccaatagcc caagctgctg ttcctctgat gacagggcgg
    91141 acatctgtta aacattctga aatctcaggc aatgccgttc gatcacctag attagctaaa
    91201 gcaatcaatg cgtttctctg caaaggtttc ttcccacgcc atgaaccagc taaatgccca
    91261 aattgctgtt tgaagtcttt attagacatc gaaagcattg gctttaattt tggatatatt
    91321 tcgtctactt ttggttccat ctcttcatga aaatgaaaat cttttccttg attgtaaggg
    91381 cagactaact ggcagatatc acatccataa atgacatttc gcattttttt acgatattct
    91441 tccggcatca tcccttttgt ctgagtttga taagacaaac atcgctgggc attcattctt
    91501 ccgtcaccaa gcaatgcttt tgtcggacaa gcagtcacgc agcgcataca gtcaccgcaa
    91561 ccaaattctc ctggtttatc aggctcaaat acaatattag taacgatctc accaagatag
    91621 acaaatgaac cgaactcttc agtgatcaac aatccgtttc gtccaataaa tcctaaacca
    91681 gctcgctgtg ctacagcgac atcgatcagt tctccagtat ctacttgcgg agctagacgc
    91741 cattcctctt ctttttgcca tttttctgct cttgtttgga tgaattcgat caatcggttc
    91801 aaacggtctc tgagtatatc atggtaatcg atcccccaag aagcacgagc aaactgcccg
    91861 cgtttttcat ccctaggcac ttcttcatgg atcctagtag gatacgcaag tgcaatggaa
    91921 atgatcgatt tcggctgatc aaatgtcatt tctggataaa gacgctcatc gatatttgga
    91981 tgttcaaagc cagaagtatg gccagctgct ttttgttctt ccaacgattc ttttaatgaa
    92041 tcaaaaggtt ccgccgtggt gaacccgatt ttgtcaattc ctaatcgttt gctttcttgt
    92101 atgatttctt cttttaatgt catggtcttc ctcgcttgct gttaacggct gtataaccca
    92161 taatatagtt tttctttttt cagctggaca aactggatct gctgatcggc attcttcttt
    92221 tcttccatcc atttttttct tgcagcaaat acttcccaat aatttgttga aattaatttt
    92281 cttttgttat ctaatgcatt aaaaaaattc aatgaaactg gttttgtact taacagttca
    92341 tggagcctta cctcttccca tggcgaaaac tcagacagat cgcgggaata caatacttct
    92401 tcatagagat ttttttgctg tgtgtacgtg aatgtttgcg ggattttccc aggcctagca
    92461 atttctacta gacgattata aaacatattc attaatttgc tgttggcaat aaattgactt
    92521 ttataatagg ccgactggat ctttttgatt actccttctg ctttgatgac tgaaaataat
    92581 gcaggccatg ctttgacggt tatttcgtcg ttttgtttaa ctaatacgcc aggtgtgaag
    92641 ccgactggag aaaggaacac aaaataaccg ataccggtat tttcatctaa aggctgaaat
    92701 tcatcaaaca accatttgcc tatgtacagc tcttcatctg gttctgttgt ctcattttga
    92761 tttgctatga ataatttagc taattctgct tcaagaaatt gaaggtcttg atccttgtcg
    92821 gtattttcct gctggctgat caatcgaaag acttcttctt taatcgtata tttatcttta
    92881 cgtgtaaaat tcatagccac accttccttc cttactctaa ctataacgga atttcttcaa
    92941 aaaaggtatc tgtacgacga aaaacagcat aatttttttt catatctctt ataaaaaatg
    93001 caaggtctgc tcctcaagct agaccttgca cttttcagct ttcttttgtt tgtgacaaac
    93061 cttcatggat cgtttcaata ttccatttca tcatctgata gtaagaatct ccttgttctc
    93121 cttcttttgc tatggaatca gtgaacagtt tatcatagat tttcaaaccc gtttcttttg
    93181 ctacccgttc catgcttctt gagtctacac tggtttccac gaataaaacc ggtacttctt
    93241 ttgctcttat ctgatcaatg atcgctttca tttgatcagg cgtaccttga ctttctgtat
    93301 tgatctccca tatataagct gctggcaaat catatgctcg tgaaaaatac ttgaatgccc
    93361 cttcacttgt tactaataat tttttgttct cttcgataga agcaaaactt tccttcgctt
    93421 gtgtatctaa ttcttttagt ttttccacat atgcttctgc atttttttta tagagtgtcg
    93481 cattttctgc atctttttca gagaatatac gtgcgatttc ctccacatat tttattccgt
    93541 tagataggtc tagccaagca tggggatctg cttttgtatg ttcttcaccg ctagttaaat
    93601 aaagaggttc tacatttttg ctaactgcaa aataatcttt tccttcttct tttttagccg
    93661 tttccatcaa gttatcgaac cagctgttac ctgtttcaag attcaaaccg ttgtataaaa
    93721 taacatctgc atcgcttgcc tttttgatgt cttctggtag tacttcatat tcatgcggat
    93781 ctgttccgac tggtacgata ctgtggatat ctatttgatc tgttccgacc tcttttgcca
    93841 tgtccgccaa gatcgaattg gtagccacga ctgacaactt ttctttactt ccttcatccg
    93901 cttggtcaga agcctgcttt ccgcaaccgg ctaataccaa gaaactaact gccaagatta
    93961 aaaagagtga tttttttgtt ttcatctatc tgcttccttt ctgaaataaa attccttttg
    94021 ttggagaaaa taaaaaagca aggataaaaa atgcggtaca tgctaacacg atcgtagctc
    94081 ctgatggcca attgtaacta taactgaaaa acacaccgac aactgcactt agcataccga
    94141 ttcctgcagc tgtaatgatc attttcagta aatggttcgt tagcaagtaa gccgtggcgg
    94201 ctggtgtgat caacatggca atcaccaaga ttgttcctac tgtctgtaaa ctgactacag
    94261 ccactaatgt caaaaagaac atcaaaagat aatggatcag cgatgtgttc agcccataag
    94321 cttttgccat tgtcggatcg aatgatgtga tcttcaattc tttataaaag aaaaagacaa
    94381 atatcaagac gattccacta acgagtgctg tcagcaacaa atcgctttcc ctaacagcta
    94441 agacattccc aaataaaata tgatacaaat ctgtcgcact ctgggcatat gaaatcaaga
    94501 taatccctaa tgcaaaaaag gagctaaaga caattccaat cgctgtatca tttttcaatc
    94561 ggctccgctg agtcacgaaa ccaatcactg ctgctgttag catcccaaaa gcagtggctc
    94621 caaagatgta actaaaacca aacatataag aaatggctac acctggaaga actgcgtgag
    94681 agatagcgtc tcccatcaaa gacatccctc gtaaaataat aaaagaaccg atgactccag
    94741 aagcaagtcc tacaagcatg gaagtgacca aagcgtattg caggaattga taattcatta
    94801 atccatcaat aaaggattgg atcatttttt ctctcctcct tttactaaat gtctgatgat
    94861 ctcaccatag gccaattgaa ggttcttcga tgtaaagact tcttgtactg gaccggaagc
    94921 gatcagctgt ttatttaaaa gaataacctc atcgaaatat tcttctactt tatgaagatc
    94981 atgatggacg atcaaaatcg tttttcctga attcttcaat tcctgcaaga tgtcaaagat
    95041 ctttcgttca cttaacgcat caatccctac gaatggttca tctaaaaaga tccattctgc
    95101 tccttgggct agagctcttg caataaaaac tctctgaagc tgtccacccg atagttcgct
    95161 gatctgtctt ttggcatatt cttccatccc tacttttttc aaagcttgtc ttgcacgttc
    95221 tttttctttt ttcccaggtc tttgtccaat tcgtaaagat ggatatgttc ctaaaagtac
    95281 aacgcctaat acatcaattg gaaaggaaag atccaattca cttcgctgtt ccacgtaggc
    95341 tattttttta cggactgagt ttaccgactg tccagaaaag gtgactttac cagtagtagc
    95401 tggtatcaac tctagcaaag atttcataaa tgttgatttt cctgcaccgt ttggtccgat
    95461 aataccggta attttttgtg gatttatcgt caagttgata gttttcaaaa cagttttccc
    95521 ttgataagcg gctgaaaggt cttgaattac aatggccgta cgttccaaat cttacactcc
    95581 tttttaggtt tacctaactt tttatttaaa tatagtttaa ctaaaatgga aagcattttc
    95641 aagtagaatg atgaaaaagt ttttttcgaa ttttcctcgc attttatgaa aattttctgt
    95701 agaatcacat caagagttca ataaggctaa cctaataatg aaaaacatgt gttgaaacgt
    95761 ttgattattt tttcttgttg actcaacaac gaaaggagtt tttgtatgga agaagaaaag
    95821 ttaactcgaa gtcttagtgc ccgtcatatc caaatgatcg cactaggtgg aacgatcggt
    95881 gtcggtctgt ttatgggtgc ctcctcaacc atacgttgga cagggccctc agtgatggga
    95941 gcctatgcga ttgcaggatt ctttttgtat ttgattatgc gtgctttagg cgaaatgctt
    96001 tacgttgatc cttcgactgg ttcttttgca aattacgcga gcgagtacat ccatcctgtg
    96061 gctggctact tgaccgcttg gagtaatatt tttcaatata ttgtcgtagg aataagtgaa
    96121 gtgattgctg taggatctta tatgaattat tggtggcctg atttgccggc aattattccc
    96181 ggaatcattg tcgtcttgtt tcttatgctg gcaaatctta tttctgtcaa ggcgtttggc
    96241 gaattagaat tttggttttc gatcatcaaa gtcataacga tcattttgat gatcattgca
    96301 ggtcttgggg taatcttatt tggatttggt aatcatggtc aggcagtagg gatttcaaat
    96361 ctttggaaaa atggtggatt cttcactgga ggcgtcaaag gatttttctt tgcattatcg
    96421 atcgttgttg cttcctatca aggaatcgaa ctgatcggaa tgactgctgg tgaagcagag
    96481 aatcctaaaa agacgatcat tgaagctgtc cagtccacta tcggtcgaat cttgattttt
    96541 tatattggtg ctatttttat cattgtgagt atctatccgt ggaatcaatt gagtgagatt
    96601 ggttcacctt ttgtacaaac tttttctaaa gtcggcatta catttgctgc aggactgatt
    96661 aattttgtcg tgattacagc ggcattatca ggttgcaatt cagggatttt cagcgcaagt
    96721 cgtatggtct atacacttgc cataaatgga aagatgtcta aaaaatttct gaaactatct
    96781 cgtcacggtg cgccttttta tcctgtcgta gcaatctcag gtggaatctt aattggtctg
    96841 atcttaaatt atcttctacc aatgttcatc aaccagtcag aaaatatttt cgttttcgta
    96901 tacagctcaa gtattttgcc tggtatggtt ccttgggtag tgattttgat cagcgagatt
    96961 cgcttcaaaa agaagcacgc agataaaatg catgatcatc cttttaaaat gccactatct
    97021 ccttatacga attatgtgac acttgctttt ttagctatcg tattgatttt catgtttatc
    97081 aatcctgaaa cgagaatctc attgattatt ggactcgttt tcttgcttta catgacgatc
    97141 cattactttg tacgcgaaaa aagaaccgga aaataaaaaa agaacgaagc ttcaccttag
    97201 tggaagcttc gttctttttt attgctttta tcaattcaat tttagcgtct caccgggagt
    97261 caggaaataa ttctccatgc tcatcccatt cagcgacaag atcgtttcta ctggtacgcc
    97321 agttcgttcg gctatttgat ttggaccttc tccttccaaa actacggttg tcgcagcctg
    97381 tgaagtcgcg ctgttggtat tagtttcaga ggaatctgtt gtgtcttgtg ttgttcgagc
    97441 ttgcatttca gaagcttcta ccgactctgc tgtctcagaa tcagaagatg ttgtgtcttg
    97501 tgtgcttgtt gactctgctt gaagagaggc gctagtctgc aaataaatat cggaaatctt
    97561 agcgacatga ttcgtataat tagccgataa ttgattgatc aaagtatcta agtctacacc
    97621 gtctttattt tctgctgcct gatacgctgc acgtaatttt ctgatccctt cgtcggagat
    97681 tgcttgaagc tcacgtgctt tttggttagc aactgctgat aaaccagcta ttccctcttg
    97741 atttccctga atttctgtct ggtattcttc aatcaatgca ggcgtctttt cttcgatctt
    97801 tttcgaataa tcatttacga ttgcttgaag ttgctctggc aaaccatttg ctgttttttc
    97861 ttcagaagtt tgtgtctctt ttgttttagt tgatgactca cttgtttgtt tcgtctctgt
    97921 tttctttgtc gttgtttccg ttatggtcgt acttttcgct tctgacgaat tttttccatg
    97981 aaaatataga cccgcaactc ctcctgctat gatcaaaaac acggcaactg ctgccccaat
    98041 catgatcatc cgcttacgag ctgcctgttt ttgctgtctt cttcgggtca tccgaacatt
    98101 ttctccccac tcattttcat catacatttt tttcaccacc aatttttatg tataatagcg
    98161 ttatcaaacg cttcatattc ttattgtagc aaataattgt cgctgtgcac atttttatct
    98221 ttgttattta taagaaaatt tcaccagttg agatgattcc aagattgtcc gtcgatttct
    98281 ccttgcagct gcattgttcg ttcgtctatc tcagccatca gtttctttat ttcatataag
    98341 agcgcacggt cttgatattc tgatttttcg cttaattcat ctaattgttg gatcagccaa
    98401 tcatttgtca taatgaagtt cctttcattt cttgcagtgt aaaggtcaag tcttcgatct
    98461 gctcttttgc ctcagtcagt gcttctacga tatatgcttg tttttcagat tcttcttcct
    98521 gcattttctg attttcctgt actctttgaa taaaccagtc aatccgctga gtcagcgatg
    98581 gtttgccttc caatgagaga tactgctgat aagcaattag cttctcccaa cgtttttcct
    98641 gggataaata cataaattgt gctaaaacga atggcggaag ataggtcata tggaatttat
    98701 ttgcgattcg ctgatacggc ctcaaaaatt cggaaatcgt atattcttct tttcctccag
    98761 cttggtattc tttttccgcc acacctgttg tcaatacgat tcctagttct ttccctttta
    98821 atacatgtgc tgctcgttcc aagacattat cttgccaaat ttttaaatga gcaggagaac
    98881 tataccagta aaacggaaac tggaaaatga tccgatcatg ctgggccaag agctgtagtt
    98941 cagtctctat atctattttt ccgtctggat aacttgattc caaatgatgc caagtagctg
    99001 gtaaaccagc agaagcttct ttgaaaaatt gctgatttaa agattcttcg atcgttggat
    99061 ggctaatgat gataagtgta cgcatccctt ttcctccttt ttagtcttcg ctttacagtg
    99121 tagcataacc gccacaagtt tcttttgccg atgcttgtca ttttaaccag actaatcagg
    99181 ttgtccaaga aactgtggtt tgtttttcca actgtttttt caaggtatcc aaagcaatat
    99241 tcttaaaatt tttgtttttc atacgtttac gatagttcgt agccgtttct ccggtactct
    99301 ttttgaacat tcggctaaat acgactagac tattgaaccc tacttgatag gcaatacttt
    99361 ccacggattc atccgtcaga gaaagaagaa acgcccctcg attgatccgt accccgatca
    99421 aatattcctt gatactggta cccatatgat ttttgaatac tcgcgacaaa tggctccgat
    99481 tgaccgctaa atgctgggcg atttcctcaa cagacaattt ttcagcataa tgtgcctcga
    99541 tgtatttgac tgtttcaaca gctaaagagg aatgaacctt ttgtacacca ccgctgacct
    99601 ttccgccatc ttttaaaagg actgataaaa aacggtaggt taatgctgtt aactgtaatt
    99661 cattttccaa ggtttcttcc gtatctttca tgcattctaa aataatgtcg atatattttt
    99721 gtatgtcaga agagaccatc gtgtattggt cttctctgaa aagcgactgc cgaatgattt
    99781 cttctgcagc actcccacca aatgaaagcc agcaatacat ccacggatct tctccatctg
    99841 ataagtaaaa cgtcgagtct cctggacgaa tcaagaacag atcacctttt ttcaattgga
    99901 attgttgatt tttcacatga taagatcctt tgccttccat cacgacatgc aggatgtaat
    99961 cattgcgaat agcaggacca aaagaatgaa acggcatcgt tttagagaaa ccacaaaaat
   100021 caaaatacaa ttctttttct acttgttgat gttccttttt taaaaaaatc gattgctcca
   100081 cgtctatccc tccttactcc tttagtataa tgcaacaaaa agttaaataa aagtcacaga
   100141 aatatattaa aaaggaagcg atttcttgtt aagtttaagt cattaaaaga tctttgttat
   100201 tcgttgtaac cggtttactt agtattatat attgaacagg agaggaatac agattatgaa
   100261 aagcaaaatg atccaacgtg tgtcctacgc tttaggcgct tttggacacg acacattcta
   100321 tgttacatta agcacttatt ttatggtatt cgtgacaagc cagatgttcg caggaacaga
   100381 taaggcaacg aatgcaaaaa tgattgctac agttacaagc ttagttgtag gtatccgctt
   100441 agttgaaatt atttttgatc ctttgattgg tggcatcatc gataatactc gtacaaaata
   100501 cggtaaattc aaaccatggt tagttatcgg cggcgttgtt agttccgtac tcttggtagc
   100561 aatctttacc aatttctttg gcttagctac tcataatacg actttattta tcatattatt
   100621 tgcaatcgtt ttcatcttat tggatagttt ttattcattt aaggatatcg ctttttggtc
   100681 aatgattcca gctttgagta cggaaacaaa ggaacgtgaa aaatttgcta cgtttgctcg
   100741 tttcggctct tctctaggtg caaatggtac tactctagtc gttgtcccta tcgttacttt
   100801 ctttacctat cttgttactc ataaacatat tgaaggcgct tcaggctggt tctggttcgg
   100861 tgtgattgct gctgttattt caggcggtac tgcgattatc actgccttgg gcacaaaaga
   100921 agtcgatact gcgatccgtc agcaaaatga aaaagctggg atcaaagatg tgttcaaagc
   100981 agttgctcaa aatgatcagt tgatgtggct tgcccttgct tatatcgctt atgcgattgc
   101041 caatgcagca acaactgccg tattattcta cttcttcaaa tatgtacttg gccaaccaac
   101101 tgaattttgg atcgttggtc tagttgctgc cttacttggt ttagtagctg ttccactatt
   101161 cccaatgctt acacgcgtca tctctcgtcg ctacgtttac cttggaggga tcgcaatgat
   101221 gatttcttct tactttttct ttacgatcgc aggttcaagt ttgccaatcg ttatcatcgg
   101281 gctagtattg ttctacttcc ctcaacaatt gattttctta tccgctttga tgacgatcac
   101341 agactctgtt gaatatggtc aatggaaaaa tggtatccgt aacgaagctg ttactctatc
   101401 aattcgccct ttactagata aaatcgctgg tgctttgtct aacgggatcg tagggtttgt
   101461 cgctatcgct tctgggatga ctggtaatgc tactgctgct gatatcactg ctcatggcgt
   101521 aacgactttc aaagcttatg cattctatgc tcctgctgct ttgatgattt tctccgctat
   101581 tatttttgct tggaagatta cattgacaga gaaaaaacat gcacaaatcg ttgagaaatt
   101641 ggaaaacaaa ttggctccag ctgatacaat ggaagatgaa cttcacgatg cagtagatcc
   101701 ttcccattaa gaaaggatct tgaaaatgaa gattacagaa aaagattttg gccaaggtta
   101761 tcacttgata accttggaga acaaaaacaa gctagcactt tctatctctg atttaggtgc
   101821 tagaatcgtc agtttaaaat caaatgatcg agaattagtt ttgggatttg acaccgctga
   101881 agaatatatc gaaaaagatc cgtatatcgg tgcttctatc ggtcgcaccg cagggagaat
   101941 cgaaaatggc cacttttctc tcaatggaaa aacttaccaa ttagccacag atccaaaaac
   102001 tggacataat ctgcatggtg gtgctcctgg atttgaatta aaaaaatggt cttatgtcat
   102061 tttgaatggc gaaaatgaag cttctgtcat ttttactact acaagtcccg acggagaaca
   102121 tggttttcca ggtacaatgg atgtggaaat ccgctatact ttgacaaaag ataatatctg
   102181 gcgagtgacc tctcgcggca ccagtgacca agatacttta ttcaatccga caaatcatgt
   102241 ttacttcaac ttgacgggag atgcttctca gtcaatcgat caacatgagc tttggctcaa
   102301 tagcgaagct tatgctcctt tgcgaacaga tagtattcct ataggggtaa aagaaaatgc
   102361 tgcaggaagt gctttcgatt ttcaaatacc taaaaaatta gcgtccgttt ttgctagtga
   102421 tttggatcaa aaaaatcttg ttgacggaat cgatcatcca tttttcttaa aagaaaccgg
   102481 cttgggtaaa gaagccgctc gcttgactag ccccgataaa agaatccaag tagatattgc
   102541 tacagatgct tctagtgtgg ttattttcac tgcaaatttc ggcacagaaa caccagaaat
   102601 gcgcaaccga aaactggcac atcacggtgg catcacattt gagactcaaa cagctccagg
   102661 tgcagagcgc ttctcagcat ttggttcgat tcatttaaaa gccggatcag tatttgaaac
   102721 agtgacagaa ttcaaaatca aaacaagaaa ggaataactc atcatggaaa tcaaaagaag
   102781 cttaaacaca aaatttgccg aaacattcgg acctaaaaaa actacacaat acttctcacc
   102841 aggacgcatc aatttgattg gtgaacacac agattacaat ggaggccatg tcttccccgc
   102901 ttccatcact tatggaacgc aaggtgtagc agcacctcga gacgataata aaatattagt
   102961 ttattccaca aactttgacg atatcggtgt cattagtttt actttagatg agctagaata
   103021 tgataaaaaa gcaaactggg caaattacgt aaaaggaatg gtccttaaat taaaagaagc
   103081 tggacactca atcgatcatg ggtttgagtt attagtggaa ggaacaatcc ctaatggtgc
   103141 aggactttcc agtagcgctt cattagaatt attagtaggt gttgtattag aagatctgtt
   103201 tgatttaaaa acagatcgct tggaactagt ccaaacaggt aaaaaagtag aaaatgaatt
   103261 catcggtgtc aattcaggta tcatggatca gtttgccatc ggcttcggtg agctagatca
   103321 tgcaatctta ttagatacaa atacgctgaa atacgaaatg gttccagtga aactagatgg
   103381 ttatgcaatc gtcatcatga atacgaataa gcggcgggaa ttggcagatt caaaatacaa
   103441 tgaacgccgt agcgaatgcg aagaagcctt ggcacgtttg caaaaaactt tgcctatctc
   103501 ttctttagga gacttagatg aagaagaatt tgaatcaact attgaccaaa tcggcgatga
   103561 tacattgata cgcagagctc gccatgccgt ttctgaaaat cagcggactt tgaaggcaaa
   103621 agctgaatta gaagctggga acttagaagc atttggtcaa ctgttaaatg attctcacca
   103681 ctctcttcgc tatgattatg aagtaactgg gatcgaatta gatacactag tagatgctgc
   103741 tcaaaaacaa gaaggtgtct taggtgcacg aatgacagga gctggatttg gtggctgtgc
   103801 gattgctctt gtcaaagaag aaaatatacc tgccttcaaa aacaatgtct atgatgaata
   103861 catgaaagtt gtcggctatg ctccggaatt ttatgttgca cacattggaa atgggacaac
   103921 aaagatcgat ccagaagctg ttcatgtttg ataaaaaaat caacgatctc agctaaaaac
   103981 aaatagataa aaataacctc tcagcaattt ccaaatgtga gccttttgct cgtatttgaa
   104041 aattgctgtt ttttattgac acggaaagag aacgtgtgtt ctaattgtgt tgaagaggtg
   104101 attgttatgt gggcgaatca aaatccggta tttgtttatg aaaaagaacc ttcaagagat
   104161 attttatgta ttgactgcaa atctttttac gcctccgtag agtgcgttga aaaggatctt
   104221 gatcccctta caactaaatt agtagtcatg tcctatccgt ccgattcgac agaaacacgg
   104281 ggtagcggat taatcttggc ttccagtcct gcagcaaaaa aagcttacgg catcaccaat
   104341 atcagccgtg ccagagatct tcccttcccc tatccaagtg atttatatat tgttgcccca
   104401 aggatggcct attatatgga aaagaacaga gaaatcaatt ctatctataa aaaatatgca
   104461 gacgaagcga accatcatgt ctattccgtc gatgaaagct tccttgatgt aacaaatagc
   104521 atggcactct ttggtaaaac aaatgcgtac gacatggcta aactgatcca taaagatgtg
   104581 tttgagcaga ccggaatcta cacgactata ggaattggcg ataacccgct acttgctaaa
   104641 ctagccttag acaatggctc aaaagacgga aagcaaatgt ttgctgaatg gcgttatgaa
   104701 gatgtaccag aaaagttatg gaaaatctca gatatcactg acttttgggg aatcggcaaa
   104761 cgaacagcaa aacgtctgaa acaaatgggt atacattctg tttatgattt agctcacgcg
   104821 gattattatc acttgaaaag caagctaggg gtcatcggta ctcagcttta tgcccatgct
   104881 tggggcatcg atcgaagttt tttgggacaa gaatatacac caaaatcaaa aagtatcgga
   104941 aatagtcaaa tcctagatag agattataca agacgagaag aaatcgagat cgttatcaaa
   105001 gaaatggccg accaagtcgg cactcgcttg agacgatctg cagcaaaaac acaagtagtc
   105061 agcttatggg taggatactc tttaggctat cttgatccaa atggcaagac cgggtttcac
   105121 cagcaaatga aaatcgaagc gacaaatgct agcagagatc tagcagatgc tttattgacc
   105181 attttccacc agcattacca ctaccaggat attcggcgtg taggcgtgaa ctgttccgac
   105241 ctcgtatacg cgacaggttt acagcttaac ctttttgaag atcctgaaaa gcagataaat
   105301 gaagcgaaag ttgattttgt tgtcgatacg attagaaaaa aatacggctt tcaatcaatc
   105361 atccatgcgc atagtctctt gcaaggagga cgcgccatcg cacgtagttc tctcgttggc
   105421 gggcatgcag gtggtatgag tggattagaa ggtggaaaag atgagacgga cagcaaaaaa
   105481 attcattgac tataacgagt atcgagatcg gccatttgga ttaaaatggg ggactgcttt
   105541 tgcgatggaa gaactagtca acggtatcaa aaaaaatgaa gaagaagcac gcaaacagcc
   105601 tcttcctaaa caacaaatga cattgcaaga aatcgatagt atactgacag aagccttttt
   105661 atctcgtaaa gcagtaatca ttcagctcaa tttaaaagat gaatttggaa gactcttgga
   105721 tgaggtcgaa gggcacttca ttggtgaagc ctatgaagat tactttatga ttgaccatca
   105781 gccgatattg tgggaagacg tacggtatat tgagttaaag gaaacaaaaa aatggtttgt
   105841 gacatgagag gttgtgacag aagtgatcaa cttcaaaaaa taagaaagga tttttcgaaa
   105901 attgcttctt aaatttttgt ggaattttgg cttatttttc gaagaagcaa cttctggaac
   105961 aacgtatatt agatatcaga ggttgtgaaa aagtcgctta gttttgagta acaagccaag
   106021 gcgctgattt cacaacctct gtctatctat ccatctattc ggtaagattc atgcatgacg
   106081 tcttctttat ttagtatgta gagccctttt tcttctgacc attcaacata aatcagctgt
   106141 tttacatctg catagccttc tttcttcaag ttctccataa gccatgcttc agtcaattga
   106201 ttggactgaa gcactttatg ctgaatttgc ccttcatcta caagcaggat cgataaagct
   106261 ttgtcttcat ctgatttttt caatacactc atttgaccgg cattctctag gataacatgt
   106321 ttggcatttt caagaaaaaa gcattcttgc tgtcttaaga ttgctcgcaa ctgctccatc
   106381 tcgatatggt tatttgtcaa ctctgtcatg ttgatgacgc cgtctttgat tagaacagat
   106441 ggctcgcctt tgacccaacg attgaccttt tcattttttt ggacgatacg ttcgatacca
   106501 taaatcatta ctgcccaaag cgcaatggca aataggacat gccctacatg gacattgtca
   106561 tcataggttg attcttctaa gatcccacct aaaacaagcg tatagactaa atcaaacggt
   106621 gtgatttctg acatggattt cttcccaagc aaacgtacca ctaataataa accgatcaac
   106681 ccgaacacca gtttcattgt aattgaaaaa atcatttttt ctccccctaa ctatctgtta
   106741 attaaattat atatgctttc tcacgaacac gcatggaata tacaaggaag aaatgtatcc
   106801 ttttactaaa aaaaggactg tgacactgta gtgaccccca aaagttagac ttttttggag
   106861 tggagaaatc cactcctttt ttttatgctc taaaatgata tttttacaca accgttacgg
   106921 ttgttttacg aaattggacg agactttgcc agtttaattt ctgttttatc cgttcattat
   106981 tgtagtaata gatatagcta tcgatggctg attttaattc ctcgaaacag ttataaactt
   107041 tcccgtgaaa aatctcttgt tttaataagc caaaaaaatt ctccataagt gaattatcta
   107101 agcagttccc tttccgagac atgctttgaa agattttgta ctccttcaat ttgtttctat
   107161 aagctttcat ttgatacgcc caaccttgat ctgagtgaaa cgtacgacga tagggacaat
   107221 cgttagtggt ctggatagct tcctccaaac cttccattac cgctaatgca ttgggctttt
   107281 cagagatacg ataggataaa atctcactat tgaacatatc cataaaagga tctagataca
   107341 atttcttttg acggataatg cctttggcat ccacttcatg gtatttaaat tcagttgtat
   107401 ccgtcgtgat tttctgatgg cagatactgg tgtagaaacg acgatggat
//
LOCUS       DAFEML010000003        99790 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFEML010000003
VERSION     DAFEML010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 99790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.003"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(552..2165)
                     /locus_tag="LP468_000222"
     CDS             complement(552..2165)
                     /locus_tag="LP468_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2079790.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="LP468_000223"
     CDS             complement(2306..3214)
                     /locus_tag="LP468_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2079791.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3414..4520
                     /locus_tag="LP468_000224"
     CDS             3414..4520
                     /locus_tag="LP468_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2079792.1"
                     /translation="MVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATTLEVYVA
                     NGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPDIISMAD
                     TSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWASDFTPAL
                     CYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFINMLAQQ
                     NQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMFVAGGWY
                     ATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQQFLTFM
                     LTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4747..5664
                     /locus_tag="LP468_000225"
     CDS             4747..5664
                     /locus_tag="LP468_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2079793.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5657..6490
                     /locus_tag="LP468_000226"
     CDS             5657..6490
                     /locus_tag="LP468_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2079794.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6573..7691
                     /locus_tag="LP468_000227"
     CDS             6573..7691
                     /locus_tag="LP468_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2079795.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7685..9583
                     /locus_tag="LP468_000228"
     CDS             7685..9583
                     /locus_tag="LP468_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL2079796.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRYYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9577..10800
                     /locus_tag="LP468_000229"
     CDS             9577..10800
                     /locus_tag="LP468_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2079797.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10886..12820)
                     /locus_tag="LP468_000230"
     CDS             complement(10886..12820)
                     /locus_tag="LP468_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2079798.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13046..13702
                     /locus_tag="LP468_000231"
     CDS             13046..13702
                     /locus_tag="LP468_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2079799.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13785..14129)
                     /locus_tag="LP468_000232"
     CDS             complement(13785..14129)
                     /locus_tag="LP468_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2079800.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIF"
     gene            14321..15250
                     /locus_tag="LP468_000233"
     CDS             14321..15250
                     /locus_tag="LP468_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL2079801.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15261..16097
                     /locus_tag="LP468_000234"
     CDS             15261..16097
                     /locus_tag="LP468_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL2079802.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16345..17121
                     /locus_tag="LP468_000235"
     CDS             16345..17121
                     /locus_tag="LP468_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2079803.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17297..18040
                     /locus_tag="LP468_000236"
     CDS             17297..18040
                     /locus_tag="LP468_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079804.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18033..19613
                     /locus_tag="LP468_000237"
     CDS             18033..19613
                     /locus_tag="LP468_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL2079805.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19864..20343)
                     /locus_tag="LP468_000238"
     CDS             complement(19864..20343)
                     /locus_tag="LP468_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2079806.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20359..21111)
                     /locus_tag="LP468_000239"
     CDS             complement(20359..21111)
                     /locus_tag="LP468_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2079807.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21228..21298
                     /locus_tag="LP468_000240"
     tRNA            21228..21298
                     /locus_tag="LP468_000240"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21260..21262,aa:Gly,seq:ccc)
     gene            21659..22384
                     /locus_tag="LP468_000241"
     CDS             21659..22384
                     /locus_tag="LP468_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL2079808.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22639..22905
                     /locus_tag="LP468_000242"
     CDS             22639..22905
                     /locus_tag="LP468_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL2079809.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22902..23333
                     /gene="ruvX"
                     /locus_tag="LP468_000243"
     CDS             22902..23333
                     /gene="ruvX"
                     /locus_tag="LP468_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL2079810.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23358..23663
                     /locus_tag="LP468_000244"
     CDS             23358..23663
                     /locus_tag="LP468_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL2079811.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23744..24889)
                     /locus_tag="LP468_000245"
     CDS             complement(23744..24889)
                     /locus_tag="LP468_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2079812.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24950..25597)
                     /locus_tag="LP468_000246"
     CDS             complement(24950..25597)
                     /locus_tag="LP468_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2079813.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25791..26084
                     /locus_tag="LP468_000247"
     CDS             25791..26084
                     /locus_tag="LP468_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079814.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26128..26439
                     /locus_tag="LP468_000248"
     CDS             26128..26439
                     /locus_tag="LP468_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079815.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26436..27060
                     /locus_tag="LP468_000249"
                     /pseudo
     CDS             26436..27060
                     /locus_tag="LP468_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27201..27359
                     /locus_tag="LP468_000250"
     CDS             27201..27359
                     /locus_tag="LP468_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079816.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27360..27722
                     /locus_tag="LP468_000251"
     CDS             27360..27722
                     /locus_tag="LP468_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079817.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27759..28607
                     /locus_tag="LP468_000252"
     CDS             27759..28607
                     /locus_tag="LP468_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBL2079818.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28597..30072
                     /locus_tag="LP468_000253"
     CDS             28597..30072
                     /locus_tag="LP468_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBL2079819.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30338..30745
                     /locus_tag="LP468_000254"
     CDS             30338..30745
                     /locus_tag="LP468_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBL2079820.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30748..30963
                     /locus_tag="LP468_000255"
     CDS             30748..30963
                     /locus_tag="LP468_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079821.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30967..31347
                     /locus_tag="LP468_000256"
     CDS             30967..31347
                     /locus_tag="LP468_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2079822.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31481..31636
                     /locus_tag="LP468_000257"
     CDS             31481..31636
                     /locus_tag="LP468_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBL2079823.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31705..32178
                     /locus_tag="LP468_000258"
     CDS             31705..32178
                     /locus_tag="LP468_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBL2079824.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32175..33869
                     /locus_tag="LP468_000259"
     CDS             32175..33869
                     /locus_tag="LP468_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2079825.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33835..34020
                     /locus_tag="LP468_000260"
     CDS             33835..34020
                     /locus_tag="LP468_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079826.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34024..35199
                     /locus_tag="LP468_000261"
     CDS             34024..35199
                     /locus_tag="LP468_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2079827.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35192..36715
                     /locus_tag="LP468_000262"
     CDS             35192..36715
                     /locus_tag="LP468_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2079828.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36771..37055
                     /locus_tag="LP468_000263"
     CDS             36771..37055
                     /locus_tag="LP468_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL2079829.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37042..37377
                     /locus_tag="LP468_000264"
     CDS             37042..37377
                     /locus_tag="LP468_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2079830.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37672..38298
                     /locus_tag="LP468_000265"
     CDS             37672..38298
                     /locus_tag="LP468_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079831.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39040..39876
                     /locus_tag="LP468_000266"
     CDS             39040..39876
                     /locus_tag="LP468_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL2079832.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40375
                     /locus_tag="LP468_000267"
     CDS             39941..40375
                     /locus_tag="LP468_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2079833.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40443..41765)
                     /locus_tag="LP468_000268"
     CDS             complement(40443..41765)
                     /locus_tag="LP468_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL2079834.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41919..43559)
                     /locus_tag="LP468_000269"
     CDS             complement(41919..43559)
                     /locus_tag="LP468_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL2079835.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43889..44359
                     /locus_tag="LP468_000270"
     CDS             43889..44359
                     /locus_tag="LP468_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL2079836.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44988..46091
                     /locus_tag="LP468_000271"
     CDS             44988..46091
                     /locus_tag="LP468_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2079837.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46375..47055
                     /locus_tag="LP468_000272"
     CDS             46375..47055
                     /locus_tag="LP468_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2079838.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47145..48179
                     /locus_tag="LP468_000273"
     CDS             47145..48179
                     /locus_tag="LP468_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL2079839.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48193..48528
                     /locus_tag="LP468_000274"
     CDS             48193..48528
                     /locus_tag="LP468_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079840.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48512..50992
                     /locus_tag="LP468_000275"
     CDS             48512..50992
                     /locus_tag="LP468_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079841.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            51048..52607
                     /locus_tag="LP468_000276"
     CDS             51048..52607
                     /locus_tag="LP468_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2079842.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52604..53968
                     /locus_tag="LP468_000277"
     CDS             52604..53968
                     /locus_tag="LP468_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2079843.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54139..55209
                     /locus_tag="LP468_000278"
     CDS             54139..55209
                     /locus_tag="LP468_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079844.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55224..55892
                     /locus_tag="LP468_000279"
     CDS             55224..55892
                     /locus_tag="LP468_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079845.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55912..56490
                     /locus_tag="LP468_000280"
     CDS             55912..56490
                     /locus_tag="LP468_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2079846.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56893..57804
                     /locus_tag="LP468_000281"
     CDS             56893..57804
                     /locus_tag="LP468_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2079847.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58060..58977)
                     /locus_tag="LP468_000282"
     CDS             complement(58060..58977)
                     /locus_tag="LP468_000282"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL2079848.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59179..59616
                     /gene="zapA"
                     /locus_tag="LP468_000283"
     CDS             59179..59616
                     /gene="zapA"
                     /locus_tag="LP468_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL2079849.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59674..60222
                     /locus_tag="LP468_000284"
     CDS             59674..60222
                     /locus_tag="LP468_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL2079850.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60337..62697
                     /locus_tag="LP468_000285"
     CDS             60337..62697
                     /locus_tag="LP468_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL2079851.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62784..63098
                     /gene="trxA"
                     /locus_tag="LP468_000286"
     CDS             62784..63098
                     /gene="trxA"
                     /locus_tag="LP468_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL2079852.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63280..65058
                     /gene="uvrC"
                     /locus_tag="LP468_000287"
     CDS             63280..65058
                     /gene="uvrC"
                     /locus_tag="LP468_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL2079853.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDAFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65203..66102
                     /locus_tag="LP468_000288"
     CDS             65203..66102
                     /locus_tag="LP468_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079854.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66095..67357
                     /locus_tag="LP468_000289"
     CDS             66095..67357
                     /locus_tag="LP468_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079855.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67520..69418
                     /locus_tag="LP468_000290"
     CDS             67520..69418
                     /locus_tag="LP468_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL2079856.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69717..70436)
                     /locus_tag="LP468_000291"
     CDS             complement(69717..70436)
                     /locus_tag="LP468_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL2079857.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70773..71105
                     /locus_tag="LP468_000292"
     CDS             70773..71105
                     /locus_tag="LP468_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079858.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71092..73095
                     /locus_tag="LP468_000293"
     CDS             71092..73095
                     /locus_tag="LP468_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL2079859.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKHQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73114..73584
                     /locus_tag="LP468_000294"
     CDS             73114..73584
                     /locus_tag="LP468_000294"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL2079860.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73605..74189
                     /locus_tag="LP468_000295"
     CDS             73605..74189
                     /locus_tag="LP468_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL2079861.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74204..75190
                     /locus_tag="LP468_000296"
     CDS             74204..75190
                     /locus_tag="LP468_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL2079862.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75180..75491
                     /locus_tag="LP468_000297"
     CDS             75180..75491
                     /locus_tag="LP468_000297"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL2079863.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75513..77294
                     /locus_tag="LP468_000298"
     CDS             75513..77294
                     /locus_tag="LP468_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL2079864.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77287..78663
                     /locus_tag="LP468_000299"
     CDS             77287..78663
                     /locus_tag="LP468_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL2079865.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78670..79305
                     /locus_tag="LP468_000300"
     CDS             78670..79305
                     /locus_tag="LP468_000300"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL2079866.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79335..80690
                     /locus_tag="LP468_000301"
     CDS             79335..80690
                     /locus_tag="LP468_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL2079867.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80882..82276)
                     /locus_tag="LP468_000302"
     CDS             complement(80882..82276)
                     /locus_tag="LP468_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2079868.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82368..83339
                     /locus_tag="LP468_000303"
     CDS             82368..83339
                     /locus_tag="LP468_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL2079869.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83336..84118
                     /locus_tag="LP468_000304"
     CDS             83336..84118
                     /locus_tag="LP468_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL2079870.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(84287..84658)
                     /locus_tag="LP468_000305"
     CDS             complement(84287..84658)
                     /locus_tag="LP468_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2079871.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84792..85235
                     /locus_tag="LP468_000306"
     CDS             84792..85235
                     /locus_tag="LP468_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL2079872.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85278..86087)
                     /gene="yidA"
                     /locus_tag="LP468_000307"
     CDS             complement(85278..86087)
                     /gene="yidA"
                     /locus_tag="LP468_000307"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL2079873.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86106..87473)
                     /locus_tag="LP468_000308"
     CDS             complement(86106..87473)
                     /locus_tag="LP468_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2079874.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87457..88287)
                     /locus_tag="LP468_000309"
     CDS             complement(87457..88287)
                     /locus_tag="LP468_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL2079875.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88450..88887
                     /locus_tag="LP468_000310"
     CDS             88450..88887
                     /locus_tag="LP468_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL2079876.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88963..89583
                     /locus_tag="LP468_000311"
     CDS             88963..89583
                     /locus_tag="LP468_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL2079877.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89772..90278
                     /locus_tag="LP468_000312"
     CDS             89772..90278
                     /locus_tag="LP468_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL2079878.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90295..91194
                     /locus_tag="LP468_000313"
     CDS             90295..91194
                     /locus_tag="LP468_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL2079879.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91281..92165
                     /locus_tag="LP468_000314"
     CDS             91281..92165
                     /locus_tag="LP468_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2079880.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(92357..92428)
                     /locus_tag="LP468_000315"
     tRNA            complement(92357..92428)
                     /locus_tag="LP468_000315"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92393..92395),aa:Arg,seq:ccg)
     gene            92488..93822
                     /gene="rpoN"
                     /locus_tag="LP468_000316"
     CDS             92488..93822
                     /gene="rpoN"
                     /locus_tag="LP468_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL2079881.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93971..95062
                     /locus_tag="LP468_000317"
     CDS             93971..95062
                     /locus_tag="LP468_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL2079882.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            95103..96104
                     /gene="gap"
                     /locus_tag="LP468_000318"
     CDS             95103..96104
                     /gene="gap"
                     /locus_tag="LP468_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2079883.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            96214..97404
                     /locus_tag="LP468_000319"
     CDS             96214..97404
                     /locus_tag="LP468_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL2079884.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            97508..98263
                     /locus_tag="LP468_000320"
     CDS             97508..98263
                     /locus_tag="LP468_000320"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL2079885.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            98379..99677
                     /gene="eno"
                     /locus_tag="LP468_000321"
     CDS             98379..99677
                     /gene="eno"
                     /locus_tag="LP468_000321"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL2079886.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        33101 a        17043 c        20570 g        29076 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaagatac aaattggtga
     3421 tagctttgct aaacattacc ctattattca gcttaagtgc atgtggaaaa actaacgaag
     3481 aagtaacagc aaacatcgca gatccaatga taaaaaaagc cactacatta gaagtatatg
     3541 tcgcaaacgg caaactgaca aactatgttg aaaatgctgc aaaaatctat aaccgcaaaa
     3601 ctggagcaaa tattgactta aaaattgtga atgtagcttc gggaacagca acagtacaaa
     3661 tgatcacccc aaaattggta acacacgaag atatgccgga tattatctcc atggcagaca
     3721 cttcagcagc aggtgtgctg gaaaaatttc aagatgcttt ttatagtgct gatgaatatg
     3781 gattttatga caaatatggc gatcagtttt atgatcaaaa attgaatatt ttgcgtcaac
     3841 aaacgagtaa tgaaacgatt attccttggg ctagtgattt taccccagca ctttgttatt
     3901 atcaaccaaa aaaatttgct gaaataggtg tagattttga agaaatcagt tcttgggaag
     3961 aatatatcca ggtggcaaaa gcattaaaag aaaaaactgg tagttttgga attgccttgc
     4021 cagaatctgg ggaccaagaa ttgtttatca acatgctagc ccagcagaat caatctttgc
     4081 ttgatgaaga aggaaatatc cgtctgaata ctaaagaagc gaaacatgct gcaaagttaa
     4141 tcaaagaaat gatcgactca gatattgtac atttctacgg tgcacaagat gctgagaaag
     4201 catttcaaga atctgcaatg tttgttgctg gcggctggta tgctacgaat atgtctttga
     4261 attttcctga tgcatctgac aaatggcgca tggctccact gattcctttt tcaaaagaaa
     4321 atccaggaaa aggtgcagta tcaggaggat caagttttta tgtccctaaa gatgccaaaa
     4381 atccacaagt ggcacaacaa tttcttacat ttatgctgac agatgaagaa tgcttagcca
     4441 acgcactgga gctgggcgtg gctacatcta actcattggc ctatcaaaca gaagcagctg
     4501 agaaaaagtt tgactactaa ggaggacaaa aatactatga actattgaat aaaatcaatg
     4561 aaaatacatc aaatactgtt ttaccagcca cttattcaga tgctacgtct tatttgacta
     4621 ccgctgcata taactattgg caaacaggtg attttgaaaa ttcatatcta aaagaagcag
     4681 aaaattttgc tcataagtac ggcgtaaaat taactggtga ttaaaaaata ttaggaggac
     4741 ttaacgatga tgcaatcttc gttaccaagc aagacaataa agaacagcaa gaaaaaagca
     4801 acagatacgt ctcataaaaa aagtgcttat ggattggtca caccttttgt tattttcttt
     4861 attgtgacga ttttgattcc catcattatc tcgtttgctt ttagttttat gaaaattggc
     4921 tactcatttg aatttgttgg atttgacaat tatctagcta tcttccgaga tccattgttt
     4981 attaaatctt acacgaatgt tttgattatc atggcaggat caattccaat aacgatgcta
     5041 ttagctattt actttgctgt tttattgaat tcagcacagt taaaaggaaa aggatttttt
     5101 agaactgtct attatattcc aaccattaca tcaacggtgg ctgtagcttc cgtattcatg
     5161 acttttttca atccgactgg gttattcaat ggatttttga atgcgctagg aattaacggt
     5221 gtacagtggt taacaaatcc tttttggata cgaatatcaa tgatcatcac gatgatttgg
     5281 cttagtgtag gatataacac tattttattt ttagctggtc ttcaagggat ttctaaagag
     5341 atatacgaaa gtgctgaaat agatggagca tcgaaatttc ggcaattctt tttattaacg
     5401 atccccatgc taaagccaat cattttaatg gccacagttt tagccactat caatggcttg
     5461 ggtaatttca atatcccaaa tatattcttt gggacttcca atggaccaga aaattcagct
     5521 ttggtcgtag gagtcaattt atataaaaca agttttgaaa tggttgattt tggaaaagcc
     5581 tctgctattg cctggacgat ggtgtttgta tctgttatat tatcggctat tcaatttaaa
     5641 ttcggaggtg ataaaaatga ctaaacaaaa gatacaaagc agaattttta cgtacgtcat
     5701 tattgtgttt ggtgccttaa tatttttgat gccatattta tatatgattg tagcttcaac
     5761 gcaaagtaat caagaaattt taagtggcgg aatcaatttc aagtttgggg atatgctatt
     5821 aaaaaactgg caagccatca tggcgagata taattatccc ttgattattt ggaattcgat
     5881 tgttattgct gtaatcagta cagttttagc tacagccagt tctacaatgg cgggttatgc
     5941 attagcaaag tatcgtttta tggggaataa actgttgttc aatacagtta tgctatctag
     6001 gatggtgcct ttttttacca cattgattcc tttattttac attatgagtc gtttaggatt
     6061 atcgaatact tatgcaggtg tgatcatccc ttcgattgcc agtacaactt cagtgtttat
     6121 gatgcgacaa tatagcagtc aatttcctac agcactgatg gaggctgcca gaatcgatgg
     6181 tgccaatgag tgggtgattt ttacgaaaat cgctgtaccg attttatcac ctacgattat
     6241 tactagtggt ttacttatct ttatgggaag ttggaatcaa tatctatttc cattagtcat
     6301 gctttcagat aaagataaat atacggttcc cttaattatc aaaaatatga cggtttctag
     6361 tacaggtgag ccaattaatt atggcgcaat tatgctaatt ttagcaactt cagtgatccc
     6421 aatggtcttg atttatgtgt gggcgcagtc taaatttaag gagaatgaca ttggagctgc
     6481 aaataagtaa aaaaaataac gaatgttaac catctagttc gttctaggag caactccaca
     6541 ttcataaaaa ttaaaagaat ggcgggatat ccatgaatga acagacgaag gaatggtcaa
     6601 gaaaaatttt gaatgtagct tctgaaaaga tagatgcgga attagacaga atggggaata
     6661 aaattccata tatttcttac aacggaaaat atacagacgt aataaaggac agaggaatcg
     6721 actggtggac caatggtttt tggagtggta ttttatggca gctctttcac aagacaaaac
     6781 gagaaaagtt caaagaggca gcaatacaac aagaacaatt attagaatct gccctgtacc
     6841 atttttcaga cgttcatcat gatgtaggtt ttttattctt accatcggct attgcacatt
     6901 atcaacagtc tcaaaacaaa catagtcgac aactagggtt acatgctgct acggtacttg
     6961 ctggacgcta taatatttca gggaactatt tagtagcatg gaatgaccat aaacctggtt
     7021 ggatgattat tgatagtatg atgaatttac cattactgta ttgggcttcg agggaaactg
     7081 gtgatccgag gttctctaaa attgctcggc agcatgcaga tacaacagct aagtatctag
     7141 tgaggaaaga tggatcaacc gggcatatcg cagaatttga tgcagaatca gggaaatata
     7201 ttcggttact tggcgggcaa ggatacaatg agaattcttg ttggagcaga ggaaatgcat
     7261 gggctttata tggattcgcg ttaagttatc gttacacaaa aaatccgtac tatctagcta
     7321 tagcagaaaa gatagcagta aattttattc agaaaatcga aaaaactggt tatattcctc
     7381 tcattgattt tgctgtaaaa gattcgaata ttgataccag tgctggagta tgcgctgcat
     7441 gcggtcttct ggaattagca ggatatgttt cctctgtacg atcaaaaatg tatcatgaag
     7501 ctgctatcaa tatactccaa aagacagaaa agcactatgc aaattggaat atggatgaag
     7561 atgggatcat tggaggcgga gcagaagcat accatagaga actgacttat aatgtgccac
     7621 tgatctattc tgattatttt tttattgaag gcttacttcg attagaacag tcggaattag
     7681 ctatttggta gtaaaaagag gagaaaatac aatgaaacat ccagtaccac tattaaggac
     7741 cagacaggat tactttgact tatttaaaaa gataaatcaa ccactccagc cgttttatcg
     7801 agcaagtggc gcacaaattg attatataca tcaaggggta ggatatggaa ataaaattgc
     7861 aggaatggaa ggattctctc gggttttatg gggagcgggg cccgcaattg accaattaga
     7921 tgaacgatgg ttgaaattaa ttctatcagg aataaaagct ggaacagatc cttcccatcc
     7981 cgattattgg ggagaaatac atgaaagaga ccagcgtatg gtagaaatgc ccgcaatgtt
     8041 attagcgtta tatcatcatg aacaattatt atggaaaaaa ttagatacag gagaaaaaag
     8101 ccagattatt cattggttct cgcaaatttt tgaatatgaa tgtgcagatg gtaattggca
     8161 attttttaag ataattgtcg gaacaattat ccaaaaattt ggttatccag ttaaagaatc
     8221 agcactgaaa gaagcatttg ataatataga aaattgttat cttcaaaatg gctggtatcg
     8281 agacagttca agaggtcgcc aagattatta taatcctttt gcatttcatt attatggttt
     8341 gatttatagc gtactagaac cagaaaagcc cattagccag atatataaga accgagctat
     8401 tgatttttct agagactata ttcatttttt tgcggaagat ggtgcaaatg tgccttttgg
     8461 tcgaagcatg atttatcgtt ttgcagtttc aagcttttgg tcagctatgt tgtgggccga
     8521 tcttttgcct tttaaattag gtgaaatcaa ggggttagtc aatcggaata taagatggtg
     8581 gatgcaaaaa gaaatatttg atgaaaaagg tatcctgaat attggttata cctaccctca
     8641 attgacattg actgaaccct ataatagtac gttatctcca ttatggctga ataagatttt
     8701 tttattgttg gcgctacctg aagaccatga gtattggacg gctaaagaaa tgcctatgcc
     8761 tattcgtgaa ggaactaaac ttctttcaga agccaatttg ctcatacaac atgataatgg
     8821 acatacattt tttttgaatg cgggacaatt agggccaaat ttccatacat tgaccaatga
     8881 aaaatattta aaatttgctt attctagtca atttggtttt tcgataccgc gagcgaatca
     8941 attgaaagca gaaatggcaa tggattcaat gctagggatt cagcgagcgg acacatatat
     9001 cacgaccagt tttaagaatg agagcatcaa aacctatgga cagttcatcg ttcgaaataa
     9061 tgtacgagac attgtatgta agaaagaggt acttgcctct acatgggaac ctactttaca
     9121 ggcaaaaatc agaacttggc ttattccttt tgaaggctgg cagattcgcg tacacaaagt
     9181 agaattagat acagaatatg ttctatatga gacagggttt gctattgaat gttctcctga
     9241 gaaagaagga ataatcatag aagaagacaa ggaaaactat agggtgagtg aagctggctt
     9301 ttcaggtatt atctgtttaa gtgacgatac tattaaacga aaatccacag ctattatggg
     9361 tttgcccaat acaaacttga tgacatggga aaacactttt attcctggat tagagggtac
     9421 atttggaaaa ggaacccatt ggctcggaac aggagtggtt gctcatcaag atcggtatta
     9481 tagtttagaa gtatggaaca atcgtcccaa aattgatttt gatgggacaa ccgggctaac
     9541 tatccaaaat aaaaacaata aaaaaagact aaaattatgc taaaggctgg tggggaaatg
     9601 cttgataaag tgatgtttga agagataata catccagaaa aatggataaa tgaatgttat
     9661 aaagaattaa tggaaaaaga atggaataat gagatcgagc gttgtcgcag acacacggag
     9721 aggttaatca aacgtatcag taacagtcag tatcaattcc caagcgagtg tcctataaaa
     9781 ggacgttatc cattaagaga caatattggt tggacagaag gattttggac aggaattaat
     9841 tggttgttat ttgagaagac gggtgatcct ttatttcaac aaacagctga aaaagcagat
     9901 atagatttta tccacaggat tgactgtcaa attatcacta atcatcacga tcttggtttt
     9961 ttgtattctt tatcaaccgt agcagattat aaaataacgg gaaatcgaaa aatgaaggaa
    10021 gcttcaattg atgctgcaga aacattactt cagcgttttt gggagaaggc aggagttata
    10081 caagcttggg gagatcctag tgatccttca caacaaggta gaatgatcat ggattgttgc
    10141 atgaatcttc cattattgta ttgggcgagt gaagaaactg gaaatcaaaa atataaaaaa
    10201 gctgctcagg ctcatattca aaatgcagca gattatttag taagagaaga tggttcaact
    10261 tatcatacat tttatatgga tgtcaaagat ggaaaaccaa gatatggaag tacgcatcaa
    10321 ggttatagtg ataattcctg ttgggctaga ggccaagcat gggggattta cggttttgca
    10381 ttaagttatc gttatttgaa agaacaaaaa tattttgatt taagcaaaat attagccaat
    10441 tattttatga atcggttgcc agaagatacc atttgttatt gggatttgat ctttgatgat
    10501 tctagcagag aagaaaaaga tacatctagt atggtgatca tggtttgtgg attattagaa
    10561 ttaatagaat caggtctatt agacaaaaca gaaaagaact tataccagtc tgctgtttgg
    10621 aaaattatgc gacaattgaa agaaagatat gctacaacgg aagaagaaga tggcttttta
    10681 acacagtctg tttataataa gcccaaaaat aatggggtaa atacaccttg tatttggggt
    10741 gattactatt atttagaagc tttagtgaga atgactagta attggtcttc ttattggtga
    10801 aaaaggtaaa tatggaattt ttgtttgata aaataaaaaa agaaaaacca aaacagcatg
    10861 aatggtttct gttttggttt tttcgttaat tttcatattc ttctaattcc aagcttagtt
    10921 cttcccattc cgtcaatttt gtttcttgat cttgtctagc agcttctaaa tcttggttca
    10981 gctcattgag ttttacgtga tcttccaggt tttctggcgc gaccatttct tgttccaact
    11041 gatcgatcca ttcatcgatc cgcgccattt cttcttcaac ctgagtaatt tttcgttgaa
    11101 ggctacggat aagcttttgc tgttctttgc tttggtaata atcagatttg ttcgtgggag
    11161 caggagcaga ttctggctca tcttgtgcca acaattcggc gatttcttct tcttcctgct
    11221 ttttctctaa ataataatca tagtctccta gatagacttt gctgccattt tcagagagtt
    11281 cgacgacttt tgtcgcgatc cgattgatga aatatcggtc atgggaaaca aaaagcagtg
    11341 tgccgtcata atcgatcaat gcattttcta atacttcttt gttgtcaata tctaaatggt
    11401 ttgttggttc atccaaaatc aaaaaatttt ctttgttcat cgctaacttg gctaaagcaa
    11461 cccgtgcttt ttcaccgcca cttagcagag ggattggttt ttctacatct tcgccagaaa
    11521 ataagaaagc acctaaagca cttcggatct ctttttctgg agtggtagga tgctcatccc
    11581 acaattctgc taggatcgtc ttgtttgtat gcagatcagc ttgaccttga tcgtaatagc
    11641 cgatggtgac atttgtccct agcgtttctt ttccacggat aaaagggatc tggtgaatga
    11701 ttgatttcag caacgtcgat ttcccgatac cattcggacc tactagagca atcgcttctt
    11761 gacgacggat atctagattg attggttcag ataaggtgac attatcatat ccgatagcgg
    11821 catcttcgat ttgcaagact acatttccag aaggcttttc tatactgaat agaaagtttg
    11881 cttgtttttc atccccttga ggacgatcca gccggtccat tttttctaat gtctttctgc
    11941 ggctttgcgc tcgttttgtg gtagaggcgc gaacaaggtt ccgagcaacg aagtcttcta
    12001 atttatggat ttctgtttgc tgcttttcat aagccttcca ttcacttgct aactgttctg
    12061 ctttcaaatc tagatatttc gaatagttac ctttgtaatg gcgcattttt cttctgctta
    12121 attcatagac ttcattgact actttatcta aaaaataacg gtcatgggaa acaatcaata
    12181 atgcaccagt atagctttgc agataattct caagccagga aagtgtctcg atatctaaat
    12241 ggttcgttgg ttcatctaga atcaaaatgt cagggtgttg caaaagcatg cgagctaaag
    12301 ctaaacgtgt gcgctgtccg cctgataaag tatcgatttt ctgatcataa aatgaagaat
    12361 cgaatttaaa cccatgcaat acggaacgaa tttcattttc ataaccatag ccgtttcgat
    12421 ctgaaaaatc gtgttgcagc cggtcgtatt cttttaaata agaactataa gcaggtgtgt
    12481 ctggcgtacc ttcgctaatg aaaatctcta gctcgcgcat ccgctcttcc atttgtctaa
    12541 cttgttcaaa agctttcagc atctcgttcc aaactgtttc attggaatca agtcctgtgt
    12601 cctgagcgag gtatccgaga gtcgctgttt tatttttagc gatctttcct tcatcaggtg
    12661 cttcaattcc agcaatgatc tttaataaag tcgattttcc agcgccattt ctgccaacta
    12721 aagcgacacg agcgcctgta ctgatttcta aatgtatgtt ttcaaataag acttctgcac
    12781 caaaatggcg agcaatctga ttggcttgta ataatatcat ggaatcctct tttctacttt
    12841 gtgaattctc ctcaaataaa aaactatttt tcaattagta gtctaccata aattccatta
    12901 tactgcgaga tttgcagaaa tgataaataa atgaataaag aataaaattt cacaatatct
    12961 gagcaatgga attgattttt tcctataaat actgctatga tggagaaatc aaagatgtaa
    13021 ttagacaata cgtggaggtc atttcgtgaa agatcatatt attccaaagg cgacagctaa
    13081 aagactgcct ttgtattatc gctatttaag gattttaaat aatgctggaa agaaaaaagt
    13141 gtcttcaact gaattaagtg aagccgttca agtagatagt gcaacgatcc gtcgagattt
    13201 ttcttatttt ggcgaattag gaaaacgtgg gtatggttat gatgtagaag atcttatgca
    13261 cttttttgca aagacattaa acgacgatca attgacaaat gttgcgctga tcggtgtagg
    13321 gaacttggga agtgctttac taaaatacaa attccatcaa agtaatagca tacgtatcag
    13381 ttgtgctttt gatgtgaatg aggaaatcgt tgggcgcatc gtagacggta tccccgttta
    13441 tccaatggaa gatatgtcag aacaaatcaa gatccaacaa atcgaagtag caattttaac
    13501 gatacccgct gaaagagcac aagaagtagt caatcagtta acggaagcag gaatcaaagg
    13561 aatcttgaac tttaccgctg ctcgattgaa tgctccgtca gatgtattga tccaaaatgt
    13621 tgatttgacg aatgaattgc aaaccttgat ctatttcttg cattctgacg caaatgcgca
    13681 ttccgaaaat acagcagaat aaaaataaaa agcgattgaa caaatgaagg caaaactttc
    13741 acttgttcaa tcgctttatt ctgtttggac aacgattatt ttgttcagaa gatttcttca
    13801 taagaaaggg aatcatcttc tgctgtcagt tcatctagta gataacggat ttttttaaag
    13861 tcgatgaacc gtgcttgccg aaagacttct tttccttgat gaaaaatcag gacaactggc
    13921 gcagtcagca cttcaaattt actagctact tctggtgttt caaatgcatc caaatgaagt
    13981 gccggaatat cataatgtgt gagaagttcc tctagtcgtg gacgaacagc gtgacaaaca
    14041 ctgcaattag gcatcgaaag ataaatgacg gcaacggatg actgttgcag tatgtcttga
    14101 acttcagtca agttagtggt ttgtttcatt tttattctcc cttttatgat agaagtgata
    14161 tgtatgagac cttaatttaa tgggaataac agaaaaagtc aattgaagtg ctttggtaaa
    14221 aaataagagt tgtgtaaaaa tttacagagc aacttgtttt ttttgaataa aagcgtatat
    14281 ttgcaaagcg aatgaactag aaataaaaag gaggaaactc atgttttctt ttattccaaa
    14341 ttcggttttg cagatgagta cgattttctt atcgatcgtt attgaagcat tacctttcgt
    14401 attattaggc tgtcttatct caggcgcctt acaagtattt ttgaccccag aacgtgtgaa
    14461 gagatggctt cctgaaaatc gtatcttctc tatttttact ggttcgatct taggattttt
    14521 ctttccttca tgtgaatgcg gcatcgtacc gatcgttcat caatttgtta aaaaaggcgt
    14581 accagttcac acagcgtttg cttttatgct gactgctccg atcatcaatc caatcgtgat
    14641 tttttccact tttatcgcat ttggcaattc ttggcagatg gcaagctggc gggtgatagg
    14701 cagctttttt gttgcccttg tgattggtgt ctggcttgcc tattttcaaa aagacgctgt
    14761 attgaaagaa aaaatcacgt ctaaagtagc agaaaatcac catcatcatg tccatgaaga
    14821 agaacaaagt gagaagaatg aaccaaaaaa tcagctgatc catcaaactg ggcatgtgtt
    14881 gacacattca atcgacgaat tttttgatac aggtcgttat ttgatcattg gcggattaat
    14941 cgcagctgcg atgcagactt atttaccaac tagaattatg ctaacgctcg gctcaacaaa
    15001 gattttagcc attatcatca tgctgttatt ggcctttacg atgtctcttt gctcagaagc
    15061 agatgcgttt ataggatctt ctttgttaag tctgttcggc acagcacctg tagctgcctt
    15121 tttggtcttt ggcccaatgg tcgatatcaa aaatctactg atgatgaaac gatattttac
    15181 aggacgcttt attttatcgc tgatcggact gattgccctt agcgttattg gattcacatt
    15241 atttatttag gagggaaaat atgctgcggt ttttgatttt atctgggtat ttcgaattga
    15301 tgatgtactt gcaagtttct ggcaaactcg atcaatatat caatgtccat tatcgctact
    15361 tagctattct ttcaatgatt ttatctgctc ttttggcttt agttcagctg tatttgtggg
    15421 tcaaaaacgg aaaagcagaa gaaaaggcac acgagcacga tcatgaccat gggttgtcaa
    15481 aaccttatca acgtggaatc gcttatgtac tgctagcttt gccagtaatc gtggggacgt
    15541 tgtttccaac agttagtctc gacactacga tcgtagaagc caaaggattt aatttcccag
    15601 taagtaaaga atcagtaggg gatccggaga tgcagacaca atacttaaag ccggatacca
    15661 gtatttattt caacaaatca gactacttag accaaatgaa tgagttgaaa gaaaagtatg
    15721 gggataagca aactatcaag atcacagatg aaaactattt agaagttatg gagctaattt
    15781 ataattaccc tagcgaattc attggcaaaa aaatcagcta tgaaggattt gtttaccaaa
    15841 caccgaacga tagcaataca gatatcttct tgttccgatt cggcattatc cattgtgtgg
    15901 cagattcagg agtctttggt ttgttgacgc atatgccgga aggagtaacg gttaaaaatg
    15961 atgaatggta taaaatagaa ggaaccatcc aatcagacta ttatcaacca ttcaagcgtg
    16021 aaatcccatc tgtagttgtt acaaacgctg agaaagtctc tgctccgaaa aatcagtatg
    16081 tgtatcgttc tttttaaaag aacaaaataa ataaacatag ctcagacagc tgacacgcaa
    16141 ggacgtcggt tgtctggctt tttttgcatg atgtattcat ttgtttgata tttattttag
    16201 aagcagcatc ctgaaagtat ttgatatcgg tttcaaaggt gttggaaaag attgtgaaga
    16261 gaattacaat ttattcctaa catgtatgtt gaaaagttgt atgaaatgat tttgatagta
    16321 aaatatcgag tggaggtact ttttatggta acgcgtatat ttattttgga tgatagtttg
    16381 gtttttgaaa aaatgctagt agaaattttg gaagaatcca gaattttatt aagtccttgg
    16441 aaatttgaga tcgttcaggg attgaacgtt atacaatttg ttgaattcat taaaaataat
    16501 gaaatctatt cctcagatat ttttttccta gacatcgatt tgaacgccta ttatagcggt
    16561 atcgaactag gcgaaatgct tagagaaaag aatgaaaagt gtaaaattgt ttatctaacg
    16621 tctcatccga ataaagcaat aactgttatt aatcgaaaga ttacgcctag tggttatttg
    16681 ataaaagaat tcacttatga aaaaaataaa aaaagcatcc aaagttactt attgaaagaa
    16741 aaagaaaact atcctgttca acatgctacg aaaaaaaggt ggacaactgt ccgttatggt
    16801 aatagcgatc actatatcca ttacgatgaa atcctttatc taatgagcat gccaggttat
    16861 aaaaataaaa taggcctagt attgaaagat gaagagattc tcgtaaacgg cacaattaaa
    16921 aaatataaaa aatcactcga atatgagtat ttatgtaaag atttaaaagc ttatatcatt
    16981 aatactgaaa acattacatc tattagcaga gtaaacgaaa tagtaacatt tgcaaatgga
    17041 gaacaactag agatgggaaa gagaagtatt gataaactaa agaattttat gcaagaaaag
    17101 atagaaaatg aatcatttta aagaaaacaa agactcatat cttacctgtt agaagagtgt
    17161 tttcctgtag aagagaacaa cccaagtagc agcctagtcg tttctatcct tttttgttat
    17221 gcactctttt tgacatttac tccaccaata acgaagggta caataaaaag taataacaaa
    17281 caaaaggagt acagaaatga ttgaattcat caatgtaagt aaaagttacg ggaaaaaaca
    17341 agcattaaaa gacttgtctc tctcgataag acaaggggaa atttttggat ttttaggaca
    17401 taatggtgcc ggaaaatcaa ctacgattaa aagtttagtt agtattattg aaccatcatc
    17461 gggaacgatt ttagtagatg gaatgaaatt gacggaaaat cgattgagta tcaaacaaaa
    17521 aatcggttat gtgcctgatt ccccagatat ttttttacaa ttgacggctg gagaatattg
    17581 ggacttgatt tcagctgcct atgaattaga cacacaaaaa aaagaaaagc gtttagcaga
    17641 attgacagcg ctttttgata tgtatagtca tcaaaatgaa acaatcgcaa gtttttcaca
    17701 tggaatgcgt caaaaaacga ttttgatcgg cacgttgctg ccagatccag atatttgggt
    17761 attggatgaa cctttgcaag gacttgatcc tcaagcagca tttgatttga aagaaatgat
    17821 gaaggctcat gccgcaaaag gaaaaacagt cattttttct acacatgtat tggataccgc
    17881 acaacagtta tgcgataaac tggctatttt gaagaaaggt gaattgattt atcagggggc
    17941 agttagtgaa ttattgaatg gctcacctga tgaaacgcta gaaaagattt atttgaaaat
    18001 ggctggaagg caagcgacag gagatggacc gtatgtataa gcgacaatta ttagaattaa
    18061 ttcgagttaa tcttttatat gttaatccac agctcacgaa taaagcaaga gagaaaggaa
    18121 aaaagggaaa gcgattaact atctatcttt tgtctcaaaa tcttttttca gggctgattt
    18181 ttttactgat ttacggattt gctatgtttg ctatgaactt tgttaaattg ccaggtttct
    18241 ttacttatta cgtggcactt tttggtatgt taggtttaac tcaaagtata tcagtcattt
    18301 ataatatctt ttttgaagga aatgacctgc aagtattttt gcctctgcct tttggacaag
    18361 aacaggtttt ttcagcaaag attttggtag ttgctttgac catcattcct tttgtttttc
    18421 cgcttctagt catgtttatt ttaaccggat ggcgagctga tctagggatt ttgcttacta
    18481 tcattatctc aatccttttg ttttctctat ttttgattat tcttttttgt ctggctagtt
    18541 tgattgtttt tggtttggct cgaacagcag tgtttaaaaa acatagaaaa acagtttcta
    18601 gtatcttgct tggcagctcg atgctgatcg catttgctgg aatcatgtgg atgaatcatc
    18661 aaacggggac tattgaaaat gagttaacag atcggcatcc gatttcgata ttattgccat
    18721 tctatgatgc tgccagtcag ccactttctc aacaaggttt attgggttgg ggaatactag
    18781 ctatcacggc tctgggattt ttccttgctg taaaacagct gatagtacca aagcttacag
    18841 agcaactgac tgattcaaac agtgagttca aaataaaaag aacccataaa aagaaccaaa
    18901 atgtgcatca gcttttattt agttacaatg ctcaattagt aaaagaacct aatttgatta
    18961 tgcaagttct ttcttcttcc ttgttaactc caatcatttt tattcttgct tttgccctag
    19021 gaggcgaaat aaaattaact gatttagata ataagttaat cggtgttgtt ttcctggtag
    19081 ggatcgcatt ggctttctta acagttaatc agacttcttt tatcagcaat cttatttctt
    19141 tggatcaaga aaattttctg tttatccgtt ctttgccaat ctctatgaac caatatttaa
    19201 aagaaaagtt cagattcgga tggatattgc agagtttttt aactggtggg atcgcattat
    19261 taagcggact gtcttttcag ctgcctttgt tttttatccc tagcttgcta tttggttctt
    19321 tattcggctg ctacttattg tcactacgtt atttcgctag agattatcgg ttgctgctgc
    19381 tgaactggac caatattaac caattattta acagaggttc aggaagtttg ggtttagtcg
    19441 caactatgat gggttcattg atcatcagta ttattcttat cgtcttatac ggaatgttgg
    19501 ctttgtttta tccattttgg ttagtgaata ttcctgtgat cggtttagtt ctaatacttt
    19561 ccgctctatg gatcgtttat tatcaacgaa cgttttggaa aaaatttgaa taaagaagag
    19621 gggccgtgac aaaaatcatg tcgcagcccc ttttttacag atagagggtg ttcaaaagtc
    19681 agtttctcag tattaagtca attttatgta aaaatgtgag aagctatttt tacaaaactt
    19741 tttttaatac tcataattac ttcttattgc tcctgcggtt acttgtcgca atgtttgtga
    19801 gatattttgt catcgctcaa ggctgaacgt ctctttcaca accttttctt tgttacactt
    19861 cgtttattta aaaagccgtt tttttcgttt catcatgatt gcgtcacgct ttactttgaa
    19921 attacggatg ttatggttaa agacttctga taatacaaga cctaaagcga ttgctccagc
    19981 aatcataatt gcttggaccg cataatgagc cgcttctcga taggattcag taacgagatt
    20041 tcgaaccgct tgataagcta aaccaccagg gactagagga accatcccgg gaatattgaa
    20101 aatcgttacg ggcattttca aacgtttaga gaaaagatcg ctgatgaatg ctactcctaa
    20161 agaaccaagc aatgaaccaa aagcagcaga tccgcctatt tgaacacaga tccagtagat
    20221 catccagcca aaagcaccag aaagaccaca acaaatcaat gaacgcctag gtacatttgt
    20281 aataacggca aatgccgcag tcgctaaaaa actaaaagaa aactgaataa atatcgtccc
    20341 catacttgtg ttcctttcct aataaaaaag ctggaaaata aaagcaatcg caaaaccgat
    20401 catcgtagca gtcatcatcg cttctgttcc gcgagaaact cctgagacat aatgtccagc
    20461 tagcaaatca cggatagcgt tcgtaatttg aactccagga actaaaggca tcacacatcc
    20521 gataatgatt agatcctgat tgcttcctaa gccaaaacgt acgctgtaga tagcggctat
    20581 gccaatcaat aaagaagata aaaattccga taaaaatttg attctaaaaa atttcaaact
    20641 atatagataa gctgcgtatc ccaatcctcc aatgactaaa gtcacaggta aatcggtcat
    20701 ctttccgcca aataacacca taattgttcc actgatcact gccgcgctaa cgatttgcaa
    20761 ccagacagga aagaaagaac ggtctcggtc gattgcttgc agttcgcagt aaagttcttc
    20821 taatgttagc tctgaagcaa catatttacg tgaaagatca tttactttta ctactttttc
    20881 taaattaatc gaacggttgg taatttgttc cattcggatg gtcgaggtac gatcaagacc
    20941 aataaagaga ccggtttgag tgacatagct gaccaaacgg aaatttccag aagctaaagc
    21001 aattcgactc atcgtatctt ctacccgata catctccgca ttgctttcca tcatgatttt
    21061 cccagcgagt aaacaagtgt ccagcaacag atctaattct tttcccgtca tagcatcttc
    21121 tccaataatt gattgattag ttttatttta ctacaaaaca taccagaagc gtaaagaata
    21181 aaaaaacttg aggaaggaat aaaagaggcg tatactgttt ttgtattgcg ggtgtagttt
    21241 agtggtaaaa tcccagcttc ccaagctgat gtcgcgggtt cgattcccgt cacccgctta
    21301 aaataggttg tgaaaaagct gctctgcaac aagtaataag aacagccaag caaaaacaac
    21361 ttcttatgtt tttaacttgg atggacttat taccgcagat gcaagctttt gcgcaccgtt
    21421 taccaagcgg ttgtgaaatc agtgtattgt cttgagtatg aagaaaattt ttgaataata
    21481 ataaatacct tacagataga gtggtgactg attagagacg aggaatccgt ctcttttttg
    21541 tatttttaag ccatcttaaa acaggtttta ttttttgctg tttctatttc tttctagtat
    21601 ttatttatag gggaacatat gttaagattt agggagctgt tagtaaagga gtaaagaaat
    21661 gagcaaaaaa acaaccaagg cgatcgtggg gatcgtcgct gctgtgattg caggggcatt
    21721 cggtgtttcc accacacaaa aagattcaga tatctttcag cagattacaa ctatttttga
    21781 ttccacacca caagcttctc aagtagcgga tgtgccagaa tatgatggaa aacatcaaga
    21841 aatagaaatc aatgggaatc agccggaatt tacaaaagag gatcttagcc tttccaaagg
    21901 aacatgggaa agctattcaa atattgataa attgaacaga gtaggacaag ccaatgctat
    21961 gcttggaaaa gatttgttcc ctactgaaaa gagagagcct ttgtatattg acccgacagg
    22021 ttggaaacaa aagaaattaa gtgacgggca atggttatat aatcgcagcc atttaattgg
    22081 tttccagctg actggtcaaa ataacaacat taaaaacttg atgacaggga cacgttcgtt
    22141 gaatgctcca tacatgcttg ctcacgaaaa tgatattgcg gcatatatca aagaaacaaa
    22201 tcatcatgta cgctaccgtg tcactcctca ttttgagggg aatgaactgg tagccagggg
    22261 agtgcaattg gaagcagaaa gcattgaaga caaaaaaatt gaattcaatg tctttatcta
    22321 caatgttcaa gatggctaca cgatcaatta tgagacagga caagcaacaa aaacaaaaaa
    22381 ttagtagcag ctattcgaat tttttatgaa tattatgaaa aaattgtgta aaaacataca
    22441 ttcaaagaaa tatagcgtat actttatgaa aagagtactt ttgataaagc tacagaaaaa
    22501 aggaaaaaaa catacaaata gtgtttctta atttattcgg aagtttggaa tatttgtttg
    22561 tagttttccc tttcttcgag taaaataagg ttgtagaagg taagctggaa ttaccttgcg
    22621 ggaaagaggt gtagaatcat gggttttaca gatgaaaccg tacgttttgg ttttgacgat
    22681 agtcgcaaaa aagaagtgag cgaaacatta gcgattgttt atcgggcttt ggaagaaaaa
    22741 ggctacaatc caatcaatca gattgtcggc tacttgcttt ctggagaccc ggcctacatt
    22801 cctcgttatc gtgatgctcg aaatttgatt cgccgtcacg aacgcgatga gatcatggaa
    22861 gtaattgtca aggactacct ctcaaatcat ggagtgaatt tatgagagta atgggcttgg
    22921 atgtcggttc taagacagta ggtgttgcta tcagtgaccc ctttggctgg acagctcaag
    22981 gagtagagat cattcggatc aatgaagcag aagaagagtt tggctttgat cggttgaagg
    23041 aattagtagc acaatatgaa gtagaccggt ttgtagttgg attacctaaa aatatgaaca
    23101 attccatcgg accaagggca gaagcttcca tgtcatacgg agaaaagatc aaagaactat
    23161 tctccttgcc agttgattat caagatgaac gattaaccac tgttcaggca gaacgtatgc
    23221 tagtagagca ggcaaatact tcaagagcca aacgaaaaaa agtcatcgat aaattagcag
    23281 ctgtgatgat cttacaaaat tatttagacg gctcaggtaa gcaattattt taataataaa
    23341 agaaaagagg taatcttatg acagaacata accattccca cgaccatgaa ggacacgaac
    23401 acatcacatt ggtggatgac caaggaaatg aaacattata tgaaatccta ctaacagttg
    23461 acggacaaga agaatttgga cgtaactatg ttcttttata tcctgctggt gtttcagaag
    23521 atgaagatgt agaattacaa gcttatgcat acatcgaaaa cgaagatgga acagaaggcg
    23581 agttagaaca aatcgaaaca gacgcagaat gggacatgat tgaagaagta ttcaatacat
    23641 tcatggcgga agaagaagaa tagactataa agctaggaga aaccttgata tgatagggtt
    23701 tctccttttt ttatttttta ctgtatgcca tattgtatgc catctagtca atatttaagt
    23761 gttgtactaa tttttcaaca gtcttttctt tcgtttcttt tgccaagtga ccgtaacaat
    23821 cgatcgtctg actaattttt gtatgccgta atctagtttg aacttctacc atagtagctc
    23881 cagcgtccaa gagcattgaa gcatgagtgt gtcttgctac atgcacaccg agaaatggaa
    23941 ccatagcttt ttcacaaata gtaatcaatc ttgcataaat agcgtggtgt gtgattagtt
    24001 ctttatagat accacaaaaa atcatagtcg gatcagttac accaagtgtc agcatatatt
    24061 tccgctgatt aatctgccat ttttttaata tagaaattgt tctttcatct agtggaagaa
    24121 ccccagcact acaatcagtt ttaggatcac tgattttata gccatttttg gattggctta
    24181 gtgttttatt gatggtgacc gtattttctt gaaaatcaat gtctgaccaa ttcaatgcaa
    24241 gggcttcact gatcctaacc ccgctataaa agagaaagcg tagtaacgtt ttatcaaagt
    24301 cgtttcgata agtttcaggt ttgctgttta ggtaatcaaa caaggtgatc agttgttctt
    24361 tactgtaaac tttgaccttt tctttatgct tagtggtggt tcttttaggc attaatacgt
    24421 tgtctagtgg attagtctca ataatcccaa gattgatagc gtagctaaaa atacgcttag
    24481 aagttgaatg aagtaccttg tattggtcag tagtttcagc ccagctattt acaatttgtt
    24541 gggctttttt taccgtgact tcattcacac gaagatttcc atattttgga agaatccact
    24601 ttctaaactt gatttcagtt ttcatgaagg tggcttctcg gacagtggtt ttatatgttt
    24661 ctagccacaa gtcataaact tctttaaacg tttcgttgtt cgctttttta ataccgtttt
    24721 tatcgtagtc cacttgcaag cgtgacaagg caagctgggc ttcttttttt gttttgtaac
    24781 ctcgtctacg aaccttatca ggtttgccag tcattttgtt cattccaaga taggcttcat
    24841 agagccaaaa tttacctttt ttagtttcat attgcttgaa tgttgccata atagttttcc
    24901 ctccatagtg tagcaagccg tgggggcggt tggaggaggc agtttattat tattttgaat
    24961 agtgtttatt tagctcagta acaagagctg tgaactcttt tagaagatca ttttcataaa
    25021 attcttgata ctcttttttc tcatctgtat ttttttctga atcattaatt aatgagtcat
    25081 atcgtaaaag cgtatttaga agagctgcga gataagcaat tggggtactc ccgtcaggaa
    25141 attcaattcg agatcctgtt ttaagatatt ttattgcgtt tgttaaataa atcttctgtg
    25201 agacagtcag gttatcttct tcgatgttat tgatagcatt agaaagatta gaatcaatta
    25261 tagagttatt tttttcaata gtttttttca attgcttttc aagcacattt cgcttaattt
    25321 cgggcatcat atgcatatct cttaatgtat aagatccgtt taatagatag gtagtggata
    25381 catctaatac ctttgaaagt tgtttaagcc tggtgttatt gggaagatta tagccatttt
    25441 cccaattact aacggcacct ttactggccg gtggggataa tttacctcca agttgttcca
    25501 ttgagagtcc cttttcaatt ctagccagtc taattctttg tcctgtctcc actgcttcgg
    25561 ggtatttttt tctagccaca ttttcaccac cattcatata ttttctctac tatatcacga
    25621 tttaaatatg tgtgaaacat aaaagttcaa aaaagtatgt taaaattctt gcaaatgaaa
    25681 aggtatgatg gtatattgag tttataagag gtatagaaat gtattcaaga gcctcttgca
    25741 tttttttaaa atctttgtat agaaatgtat gctaacgagg ggggataaat atggaattaa
    25801 aaattgacaa actcacgctt gatgatccag cttttaaaat tattgacgat cgagttgttc
    25861 aacaagtaga gcaaactcaa ggaacgttac tttcattatt agaaaaaaag taccagtttc
    25921 caaaatatat gaacaaggca caagctgcta agtatatgaa cgtttcatac aatactatga
    25981 tgcagaaata tgttcctaac ggtttaaagt tgattatagt tgatggagtc gtaagaattt
    26041 cacaagatga atgtgatcgc tttatggaag aataccaaaa ataaacgcaa gccgtggggg
    26101 caaagggatt aataggagga aataataatg gaatcgacac aaaataaagc aatcgaaaaa
    26161 gtattatcaa caattcttac agaagacaca gcggcagaat tagcaaactt ggaaggcaaa
    26221 gcgctagaag aaacgtttga atgtttgtac gaacaaatgg actatcaaaa attgctacca
    26281 caagaaccaa cggtaagcgg agtattgcgt ggcttgaacg atttagtaca agcagagttt
    26341 aaagaacgac tttctattga agagtatcaa gaaattttgt atcagcaagt tgagttgtta
    26401 gcgagcttgc tagggcttga actggaggac gttgaatgaa aactgaaatt tggaacggac
    26461 acattataag atttgtcgat attaatgatg aatggtgggc agtggcgaaa gatgttgcgg
    26521 aagcgttagg tcttaaacag gttactagag ccattcactc tttgcctaaa gatggggtta
    26581 ctactagtaa ggtcatcgat tcattgggca gaacacaaga tgtaaacatc atcaacgaaa
    26641 aaaaatattt accgcatggc attcaaaagc cgtaaaaaag aagccgaggc atttcaagac
    26701 tggattttcg acatcatcaa agaactacgc cagtccacag gacttgaagg ctttcaagta
    26761 ttccgcatgc tagacaaaga acaccaaaaa gaagcaatga ctaaattaag ccacgctatt
    26821 actgaaccaa aaccagtaga ctacattaaa gcgaatgtga tagccaataa agctgtatca
    26881 actatttatg gtcattccaa aatggtaaaa aagaaagata tgactcctga aatgttggtt
    26941 gatcgtgaac ctattttaga tgagacagta gaattaatga ctgttaaaga aaaatatggg
    27001 ttgcagtttt cagtgagtga gaaaatttat aatcgttctg ctgaattgca gacaacttag
    27061 gagcattaac atgatcgaga acaaagaaaa agccttatcc ataacagtct tggcggacag
    27121 gataaaggca acttaattgg gataaaaccc gatattcttt gttccgatta taccatatta
    27181 aaaaatcgga gggaaccatt atgaaacgaa acttaattat aggaagcatt ttaatcggcg
    27241 gaattttcgg cttattacca ttaattgcaa aaatagctat ctttgcagga ttagcgttat
    27301 atctcttcac tgcttatgac gagtacgact atcaattaag aactggaggg cataagtaga
    27361 tgtacaaaac aaaactatta aaccaactcg atagccttga attagaggaa attaatcaag
    27421 ggatcgctga actagaaaat aatatcggga aaacctactt tggaaattca ttcaatgaaa
    27481 aactaacagt tttgtatgta ctcaaaaaac atgcagaaca caaaataatt tgtcgagaaa
    27541 tcaacgagct aaaaaatcag attttaaccg catggttaaa cattactgat atgcaagaag
    27601 caagggtgaa aacatttaat acatgggtaa agtatcagaa tcaattaaaa ggtgctgaat
    27661 ttgttcggga tgggttgaaa tacgaacttg agcagttgaa gctcatggag gtgtctgaat
    27721 gatttatacc agtattttga aaaaggagga gaggtttatt ggcaaataat tatcaagcag
    27781 caacggaatt acaaaagtcg ggatggtcaa tttatccctt atctcctgga actaaaattc
    27841 caataaaagg ctctagtggt tggaatgatg caactaacga ttctaatcaa attaatgaat
    27901 ggtggacgga agatgcaact agaaatattg ggttaatgct tgaagatcat caaatggtgg
    27961 tagttgacct agatcaacat tctgaaacac gaaacggcgt tgagaattat aaaaaacttg
    28021 cttcaatgta tgatccattt ccttctactt atacggaaat cacaccaggt aaaggaatcc
    28081 atttcttctt taaaattcct gatggtgtaa ttatccaaca agaaacaggt gcatttgctg
    28141 atatcttcgg gcgtgatgat aaaggtaaaa gtttaagcgg gattgatatt atcactaaag
    28201 gagttccaat agcgccaact atgattattt caagaagtgt tgggagagca tatgaaccta
    28261 ttgaaaacgt atctctaaat aatattgcac cagctcccga ttggctagtg aacctactgc
    28321 taaaaaaacc gcaagaaata aagactcaat accgacccgt agcaaaaaca gggacagcaa
    28381 aaaaattaga tatgattgtt caaggcgctg gcgaaggtag tagaaacgat catttaacta
    28441 agttatgcgg ttggttacta tggcacggtg tagataatca aactttagca gaattgattt
    28501 atacagcaaa tgcgtacaat gaaccaccgc taaaagataa agaagtgaat caaattattc
    28561 gatcgatgat taaaaaagat ttgaggggga aagctcatgg ctcataagca taaattagat
    28621 agtattttag actttcccga agccagcgag cgtgaagaca atatcattga attgaaaacc
    28681 tggatgtcac gattaagatg caataaagac gatcagatta aaagtaacag tgttgtgaat
    28741 gcagaattga ttttaaccaa tgatagcaat ttagctggaa caattgctta taacgaattt
    28801 agcggataca ttcacctatt aaaagattct ccttggatca atcgtaccgc tggagaatgg
    28861 gaagacagtt ttgaggatgc cttaacggca tatattgaag aaaactacaa tgtagttttt
    28921 gatgacaaca aaatacacaa agcagtagta aatgtggcta gaaagaatgt tttcaaccca
    28981 gtaaaagaac gtatcgaaaa agttaaatgg gatcaacagc ctagactgga aacactgttt
    29041 attgaccttt taggggtaga cgacaacctt tacacacgag aagtaacaaa acgttggata
    29101 gtcggatcag tcgcacgtat ctataaacca ggaataaagt ttgagatcgt tccagttttg
    29161 gatggaccgc aagggattgg taagagtacc gttccagcat tactttacac ggatgatttt
    29221 ttcaccgatt cattagattc gctaggtgaa aagaaagatg attatatgca gcttcaaggc
    29281 aatgtaatta ttgaacttgg agaattatct tcaatgaaca aaactaaaat tgaacagata
    29341 aaaaacttca tcagtgccaa gatcgataaa attagacctc cttatggtcg gaatgtcata
    29401 gcttgggcaa ggcaatgtgt atttattgga acgtcgaatg atgggcagta tttgaaagat
    29461 gatacaggaa accgccgttt ttatcctttg ccttgtaaga ataagccaaa gatgaatccg
    29521 tttaaaacaa aggatgaata ttttcttcaa gtgttagctg aagcaaaggt gctttttgat
    29581 aaaggacaac gaatctattt tagtcccgat gaagataaag aagtcttaga aattgcaaaa
    29641 gactatcaag aggatgccaa gatggagaat ccaattaaag aagcaatcac taaatatttg
    29701 gaaatggaaa tcccgtataa atgggaagaa gctccagcgt gggcgagacg ttcttattat
    29761 cagaactatc ctgacagtaa atgtaatgag aaaaatttac agcatttcta taatggagct
    29821 actatgcaac aagagtttta tttagttgat agcgtactca ccgctgatat tttggaagct
    29881 gtttttgata aacaagcaaa ggatttattg aatggtcgat cagatgcaga aactaaaaag
    29941 attgccttga ttattagcag tattcctggt tgggaacgga agcaactgcc aaaaagaaat
    30001 aaacgacgag gattttacaa taagtcaaat gcctatgaaa ataaaaatcg agctggaaag
    30061 tacaaaaagt aacgggtagt aacgggtcag taacacctag cccgttacta gtttaccctt
    30121 actgccccaa gggatacagc aatttggtaa cggggtaaca ccttatttcc ttaaaacttt
    30181 tgaaatagtt agctaatatg ctggggaata atgttactgg attttacccg ttacctgtta
    30241 ccaaaacgct agaacccttg tccccgttgg gattgagtgg taacgggtac ctgttacgta
    30301 ggtgttacca cgtgttacga atcaaggagg aaagtaaatg ctcaatatta tttcaacaaa
    30361 caaagcaccg aactttcaat atacagatga aatggatcgg tttctaatga acacgctggc
    30421 atttagtgtg ggattggtaa cagaagatta ttccacattt gatccagaag tattaaagat
    30481 aatggaagaa gaacctgatt ggctgcagga gtcagtagcg tggtgtcaat cgctagtagt
    30541 gggatcattg gtagatagtg gcaactatga tgatacaggt gagctaatgg atgaatttaa
    30601 ttgtctgctt aacctatatg atcgagcgag acaacgagag cttacatcga atgaggataa
    30661 tttgttttta aacatccatg ataagttctt ggctttgcta ctaacagatg atgaattgat
    30721 aactaattta ttggaggtag aataattatg catatggaaa gtattagata cttcgatggt
    30781 gagaaacaca ttgagtattc aaacactcaa gaagatgtag actttattag ttttgaggaa
    30841 gataaaatca ctaaagttaa ttttaaagac ggaacgtgct tgaagatagt ttcgccttat
    30901 attgaataca aatcaaaatg ggaacaagat gattctgacg aacgagatcg ctttggttgg
    30961 taatctatgg cagttaaaaa acaatgtaat catgctggat gtaaaacatt gattgattat
    31021 aggcagaagt attgtgggaa gcataaagca aagcaaacgg caattaagcg tgaagaaaga
    31081 aagcaaagcg aaggtaaata ttttcaattc tatcaaagta gaacatggcg aaaggcttca
    31141 tacttgtatc ggttaaatca tccagtatgt gaggattgcc tagaagaagg cttgataagg
    31201 aaagctgatg ttgtagatca caaaattgaa ctaaaagatg attggaatag acggttagat
    31261 gaaactaatt ttcgttcttt atgccatgca caccataatt ccaagacagc caatgaaaga
    31321 caaagacgag aaaagagtac cctttgagtt aagggggcat agtgtgaaac ttactgacaa
    31381 tcgatgccta ctcattttgg tacaaataac cgttgtgaaa aggcataagg gtaattacaa
    31441 ataacgatta cacttgtaat cacaagtgaa aaagtatata atgaaagtag gagatttatt
    31501 gaaaaataca attgttatta ctgataaaac agggaaacag cgcaccattg agttacctca
    31561 ttttggtcaa gtgaccattc aaatgcagaa cggaaaaatc atttatatag ataaattaga
    31621 taaagaaaaa ttctgatcga aaaacgaagg aatgtgagct taattgctta cgttcctttt
    31681 tcttttgtct gaaaggagga caacatggga caccctaaaa tattacacga tacaaaaggc
    31741 aatatatcaa gtgaagaaaa agcaatccgt gtggacgcta gagaagaatt gttcaagcag
    31801 caaccattaa taaatatcac gccccctgac tggatggcag cgagcgctag aagtgaatgg
    31861 aatcgtatcg taccaacatt aaaaaaagat tatccattga gtgaagcaga ttatggttca
    31921 ttggtagcct attgtttagc ctttgctcga atgaaaacag ccgaagccga gataagaaaa
    31981 tcaggtacgt ttatcacatg cgaaaacgga gtaaagaaag ccaatccagc ggttcgggtt
    32041 caatcacaag ctatgagtga tttgaaaaaa caagccacct cactaggtat gaccttagaa
    32101 tcacgatcaa aactagcttt gaacaaggtt aaaaatgatg aacccgaaga cccgttcaaa
    32161 gagttgatga attcatgaat gattacattg agaaagtcct atcaggtaag ctgattgcac
    32221 ccaagaaaat tatccaagcg tgtgagcgtc atataagcga tttggagcgt tctaagtcag
    32281 atagcttccc ttatgtgttc gatgaagaac aagccaccaa agcgattaaa ttcattgagt
    32341 tgctaccatc tacggacggt aaagcaatca agatgttagg atttcaaaaa ttcattctag
    32401 gcagtcttta tggctggcgt actaaagaag ggaattacag gcgattcaat cgagcgttta
    32461 ccagtatgag ccgtaagaat gggaaaacgt atatcgcaag tggcatggct gccaatgcgt
    32521 tgattatgga acaagaacca gcagaagcaa ggcaagtatt gtttgtaagt aacgctttga
    32581 aacaagctaa attgggctat gatatgctgt ctaattcact tagaaacgtg gtcaagtcta
    32641 gtaagttttt aagaccacaa ctgaaaatta tgaactctaa gattcagcac ttgccctcta
    32701 attcgttcgc tatggcactg gctagtgaaa ccagcacgct agatgggttt gcaccaacaa
    32761 ccgcaattct tgacgagtgg cacgaagcaa aaactcgtaa aacgtacaac gtcattaagt
    32821 caggaatgac ccaacaaaag aacggcttat tgtgtgttat tagtaccgct gggcttgatt
    32881 taaacgttcc tatgtacgag gaatacttat tgttagatcg tgtgctaaaa ggcgaagaac
    32941 aagccgacag gtactttata gcgatatggg aattggacga tcccgaagaa attcacgatc
    33001 aagagaaatg gatcaaagcc aatccgattt ttgaaagtga agaaatcaaa aaagtaatga
    33061 ttccaaccat tcaagatgat gtgaaccttg ctttgaaaca aaataacctt aattctgtat
    33121 tggtgaaaaa cttcaattta tggagacaag cgagtgagga cagctatatg attgctgaag
    33181 actggcaggc aaccgaagta gaaccacaag atattacagg caagcccgtt tatatcggag
    33241 tggatttatc taaaacagat gatttaacta gcgtttcatg gatcgtaccg ctagataacg
    33301 gcgaacttta ttgtgattca catagctttg tagccaccaa atatgggctt caagacaaag
    33361 aaaagcgcga cggtttgcct tatcgagaac tagaaaaagc tggtgagtgt tccattactc
    33421 aattagaaag tggaatcgtg gactatgacc aagtatttca gtttattcaa gatttgattc
    33481 aagaaaatga tttggaatgt atggggattt gttatgaccc gtataacgct aattcgctta
    33541 tcagtaaagc tgaaaaagcc aactacccaa tgttagaagt aagacaagga acgattactc
    33601 taaacgttcc gacccgaact tttagagaac aagtttatga aggcaacgtt attcacaata
    33661 aaaatacgat tctcacccat gcagtgaaca acgctatttt aaaaacggat aacaacggca
    33721 ttcagattaa taaatcaaag aacagtaaca aaattgatcc aatagctgca ttaatcaatg
    33781 cctatgtgtt tgcaatggat tacttcacca caacggaagg agcgaaagca gacaatgaat
    33841 tttatacaag tgaagaattt tctttctaat tacattcata ccgttctttt acttcttgga
    33901 ttggtgtgtg tgttggttgc tatcacctta ctaacaaatg tctactatgg cttgttagcg
    33961 ctgggcatag tgcttattgg ggtagcggtc atgctaaata cagaacagaa gggaggttaa
    34021 aagatggcat tttttaaagc gagacaaaat acaacgggag atcctttcct acaacatgtg
    34081 gtatcaatcc aatcggatga ttacaccacc agctttacaa gcgttcgtgc attaagaaat
    34141 agtgatgtgt ttgcagccgt tcgaattatt gctagtgata ttgcttcaag tccgattcaa
    34201 ttggtcaaaa acaatatgcc acaagctgat aatgaactgg tgaagttact aaacgagaaa
    34261 cctaattcag aaatggatgg ttggcattta aagtttgctt tggcggtcaa tatgttgcta
    34321 aacggtaata gctttgcaga gattaaacgc aacggtgaaa aggtagaaga aattcactta
    34381 ttacctaact caagtgtaac ggttactcaa ttagataatg gtacgttgtc ttatcagatt
    34441 ggtgataaaa aaagacgtgt gaagtctagc gatattttgc acttcaaata tttcacccaa
    34501 gatggtttaa caggattacc accactttat gcgttacgtg atgaactgaa aattcaacaa
    34561 gctggcaacc gcacattgca caatttcttt actcgtggtg tcagtgggtc aggtattttg
    34621 aaggttcata agtcagattt agacggatca gcaaagaacg caattcgtga aaagtttgaa
    34681 gaagccaacg gttcaagtag tggagataat gctcttagaa cgatcattct tgatgaaaca
    34741 atggactaca aaacattaga aataaacacc gatgttttga agcttatcaa ttccaatgat
    34801 tggaacacaa aacaaattgc caaggcgttt ggtgtaccga ttgagcgttt aggcgttgaa
    34861 aatgaacatt ctagcaccgt tcaaagtaat ctccagtata tccaaagtac gctgattcat
    34921 tactttaatg tgtttgtgag tgaattagat acgaaacttg aaaccaatat ccgatttaat
    34981 tccgatcagt tactagagac tgatcctgaa acaaaagtaa aaaatgtatt ggatcaggtc
    35041 aaagggtcac ttctcacgat taatgagggg cggtcgaaaa tggggctacc ccccatggat
    35101 ggtggcgatc gtttactagc aagtttgaac tttacgtatt tagatacgtt ggagaaatat
    35161 caattaaaag aacaggaagg agttacacca gttgaataat gaagaagaaa aggaaaaacg
    35221 gctgacagaa gaagctgagc taacagccga ttctcccaaa gtagagaaag aaaatgaaaa
    35281 acaaccaaca gacggcaaaa ctatttcagg ctatgcgttg aaattcgggc aaccgtcaaa
    35341 agatttaggc ggctttgtag aagtgattac acccgaagca ttaaaagagg tggatttatc
    35401 aaatgtgttc ttattatatg gacacgatta ttcaaagcca ctagctagtg tcaaagcagg
    35461 tacgttgaaa ttgaatgtcg atgatacagg attacatttt gaagcagagc taaccgacac
    35521 gacctattca aatgatgtgt atgagaatat ctcaaaaggg gttgttgatt ctatgtcctt
    35581 tgggttcgtg cttggattag attcattcga caaaaaagaa gatggcacaa ttgaacgatc
    35641 aatagataaa atcaaagcac ttaatgaaat tagtgtcgtg accgttcccg cttatgattc
    35701 atcaaatgtc caagtaaata agcgttctta cgaatcgttt atgagtaaca accaagcaaa
    35761 acaaacaaac aatagcttag aatccacttc taaagcacaa aaggagagta ataacatgga
    35821 aaaaacttta atcgataacg aaaaaacaga attgcgtggg tatgaagaat atatccgttc
    35881 acaaggcgaa gtgcgtgatg gagtcactac tgtaaatgca gcggcagttg ttcccgaaga
    35941 agtaatcggt gaagtctttg atttgaaacg ttcaaattat aacttagctc aatatgcaac
    36001 agtaaaaaca gtatcaaatg gacaaggtaa atatccagta gcaactaacc aacaagcagt
    36061 gttagcaaca aaagctgaac ttgctgaaat tggtgatatt gacgctgaaa tgtttacttc
    36121 agttgattat aaagtagaaa ctcgtgctgg taagattgcc ttatcaaatg aggttgtgga
    36181 agattcagca gtgaatattg tacaagaggt caaagatcag ttagcgaaat tggtagaaaa
    36241 cactgacaat aagcatatca tggatttatt aaaaacattc actaagaaaa cggctgctac
    36301 gttggacgat ttgaaacaac tatacaatgt ggcattagac ccagcattaa ataaaatggt
    36361 aattctaaac caaagcggat attaccacct agatacattg aaagattcag atggacgtta
    36421 cattttacaa cccgatgtga cagcacctag tggtaaatca ttattcggta tgccagtagt
    36481 attgattgca gatacattgt ttgccaatcc taaagctgga acattcccta tgattatggg
    36541 ggatattgca caatctatct ttgttgctcg tagaaatcaa gtaacgactc aatgggaaaa
    36601 attcgattac tactcacaag gacttgcagt gatcgttcgc aacgattata agaaaattga
    36661 tcaaaatgct tcagtgtata ttgagtttac gccagttgta acaccaaaag tatagaaaaa
    36721 tattgggcgg cggtttatcc cactgccttt ttttcattag gagagataaa atggtaattt
    36781 tggatagcat aaaaaaaagt atgcggatcg atcacactat tgatgatgac tttattcaac
    36841 aattgattga tacagcaggc gaatatataa aaagtgctat tgatagtagc gcaacggata
    36901 aagatatgga taattatcag caatttgatt tggcggtgtc attacttact caacattggt
    36961 atttgaaccg tcaagaagcc agcagcgaac ggataccagt aacggtacaa gcattagtac
    37021 aacaaatgag aggtgcttat tatgccaatc attaagaatg taaatgaatt gactgagaga
    37081 gtcaagttta aaaagacaaa acgggtaaaa gatgaagatg ggcagatggt ggatagtgaa
    37141 gaaactgtat ttgaatgttg ggctaatgtg cgttcacaaa tgctaaaaga cgtgcttgct
    37201 agtgtaggta ccattcttga aggaacgttg acgtttatta ttcgatacga tcaagattat
    37261 gaactaacaa acgatatgaa agtagcttgg aaaaacaaga gttataaaat tatttcaatc
    37321 aatgaaggaa cggcgtttaa agattataca acgatcatag ctaaacagat ttcttagaat
    37381 gattacactt gtaaacgttg tgggtattta gtataattaa ggtagtaaat gaagggttag
    37441 ctgcctgaat tttgcaagac ttagctagtc gaaatctatt gttggactga aaattgtagg
    37501 tgtggttgca aacatgctgg actaagaaag atgatagatg atgaacgttc aattttaata
    37561 caggcatgct aggactgatt ggatggtttt ggcaagctga ttgtgtagaa atcaaagaac
    37621 acgtctgttg tggacgtgtt ttttttgtta taattcaaaa gaggtgattt aatggacaaa
    37681 gcagagttta caaattttta ttggaagtat tatctacatt tagaaaatga gtttattaat
    37741 accacagatt ttgtgatgct cgatgagaat aatttcaaaa cattctctat tgaatatcaa
    37801 aaactactac tagcgattgg ttcggagtgt gagattattt tcaaagaact ttgcggattt
    37861 gatagcagta gcaataaaag cataactgat tttaaagctg ttattaaatc tagcgaatta
    37921 atgtgtttgg ataatggtgt tagggttatg aattctttaa cattgacttc actaaaacct
    37981 tttggagatg ggtggcctga agatacacca gattggtgga aaatatataa cagagtaaaa
    38041 catggtcgtt cttcaaatta taaggaagca aatttggaaa atgtgttgta tgctttagca
    38101 agtctatatt tattagagga atatttgcat aagaaagtaa tactagaagg tgaagtagac
    38161 tttataagtc cagagtcaaa tctatttacg ttatcttggg aaagaaaaca ttcgtcgatg
    38221 caaaaagtga cgtttgaaaa agtggattca aattatgtag ctccactcat tgattttaaa
    38281 gaacaagaag aaatttaaaa acccccacgg cttattgaag tttttgtatg ccatattgta
    38341 tgccatttgg tttaaatcgc ttgaaaaata gtgatagata actctaattc atttagtcat
    38401 aaacgctgtt ttgataacct ttatagttct ttgatatggg tttctcattc atggcggaag
    38461 aagaagaata gaacaaaaga atgaattaat aagatataaa aaaagggatt gtgacaaacg
    38521 tcttgtcaca atcccttttt ccaaataaac gatgttcaat cagctgcccc tcggcattcg
    38581 ctcgaaaaac ggcgaaatat gaagaactat tttgccattt gtttctctaa taatcaggtc
    38641 aaaacgttga cttcacagtc tcttccttaa acggtgttct cctgccaact cctcggtcac
    38701 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    38761 agctgaacgg caggctcacg acctctttct taaacggtgt tcaaaagctt gcatctgcgg
    38821 taataagttc aaccaaacga aaattatgag gagctatttt tgtttggctg ttcttattac
    38881 ttgatgcagg acagcttttt cacaacctct tttcgtttag cactaaattt ccttaaaaag
    38941 tagaaaagct ttcgaagcct cgtttgtttc ttttactgta taataaaaga aaagagtaac
    39001 aatcgctaaa agatataaac aagagaaagg aaatacaaga tgattggtct gatttatttt
    39061 gtggtgatcg ttctggcgaa cacagttggc gctatttccg ggatgggtgg aggcgtgttg
    39121 atcaaaccga ttcttgatct tatcggcgcc cattctgttg cagggatttc tttttactca
    39181 acagttgcgg tattcacgat gtccattgtt tcgactgtgc gacaagtatc aagcgggaaa
    39241 tcactgaatt ggcagattgt cggttgggta tctagtggag ctgttgttgg aggagtagtc
    39301 ggcaacattg tattcgaagt ttttttacag ttatttgaaa acgagaagca tgtgcagctg
    39361 atccaaattt ttttgacggt attgaccttg gtttttgcgt tcttctacac caagcatcat
    39421 cagccaaaat ttcatttgac gtcatggact tggtacctta tatgtggggg ggttctgggc
    39481 tttttagcta gttttttagg tattggtggt ggaccagtca atgtttcttt gttgatgctg
    39541 atgtttgcat tgccaataaa agaagcaaca ctatattctc tatctacgat tttcttttct
    39601 caactggcaa aattggtaac gattgcttta acaagtagct ttatgcgctt tgatttatct
    39661 atgttgtttt atgttatccc cgctgctgtt attggaggtt tgtggggagc aagatttagc
    39721 agggttttgt ctccaaaaaa agtgaccttt atttttcaag taattgtcct cgtggttctt
    39781 ttggtcaatt gttacaatgc ctttgtcatc ttacaaacat taggagaatc tagactaacg
    39841 caagtcaaaa tcactgaaac atattgttct aaatgaaaaa aagagtatac tatgataaaa
    39901 aaattcattt taaaaaatca gaaattggct ggtgatttgg atgttacggg aaatgcgttt
    39961 agaagatgca gaagcactac gtgaaatcaa tgcggatcaa ttagggtatg atataccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gctgaaggag ccagagaaaa attttttctt
    40081 ggtttatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttt agcgatccaa tgttcaatat tatggcactt gctgtgtcta aatatgctga
    40201 aaaaagaggc atcggaaagg ctttgatgac tggcgtagaa gaagaagcga aaaaacgagg
    40261 aataacgaca ataaggctta attctgcaga atacagagta gaagcacacc aattttatga
    40321 acacatcggt tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatctt
    40381 tatcaaaaaa atacccgatc accaagccga tacttgatga tcaggtattt ttgttttttt
    40441 gactaagaaa gtaattgcat caagaaacca gagatgatca aaacgatggc accaccaagt
    40501 cgattgccca tttgagcaaa agcaataagt tccatccgat tagctgcaga taagacggct
    40561 acatttcctg ttccgcccat cgagttgttg cataagccag cagtaatagt tgattcaatt
    40621 ggatataaac caaacaaacg accgacaaat cctgaaacaa ctgaaatcgc gataacactt
    40681 gtcagacata agacaacaaa ttgccatgtc aaagcagaag ctaatacatt cagattcagc
    40741 aacgcaatac cgataccggc aagaacagct gctgtcaagt ttttgacaat caagttattg
    40801 aacatgatag ctgcatcttc ataatactct ggtaataggt tggcgatttt acagatgaca
    40861 acgataataa tcataaatgc gtaagcatgg actttaggaa caaaatagtt accaatttgt
    40921 cctaagatga agaaagtcaa tgataccatc aaaccaacac ctaactgtgg aatggaaggt
    40981 ttcacagttc gaggttttcc atcgccaaga tcgccttttt ccattaattt accattgccg
    41041 ttgaattttg gcattgattg tccagcacga gcaactaatg ctgcaccgat gatagctaag
    41101 acatttgtca ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc atccgtacct
    41161 aaaacatttg cataaatcgt tgataaagga acggctccgg ctccaacacc accagccatc
    41221 gcaggtaatg agatgtataa aacggaattt gcaaaaccat ttccgataag catgcccacg
    41281 agtcctacgg caaaaaagga gacgaccatt gaaataagtg caacgggaat aaaacgaaca
    41341 gaagctttca tcaatagatt acggttcata ccaaggatgc taccagtaat caaggcagca
    41401 atataaaagt cccaaaagcc catattgctg acaaagtttt ctgtggattt cactacatat
    41461 tcaggtaaga tcccaaatgt agcaatcgca gcagaagcga agatcgcaaa aacggaacca
    41521 ccacccaaat aacttttgac gatagggatt tttgtcccga taaaatgaaa taaattaccg
    41581 aaaataacca aaactgcgat tggtccaatc atattcgtcg gtaatttccc taaagccatt
    41641 gcaatgatca ggacaaggac catgatcaaa taaagtggca aacttacgcc ggtgattttt
    41701 gtggaccaaa aaccttcttt tttcttttcc tcaactgcag ttgcagttgt tgttttttgt
    41761 gccattttta cagatccttt cttattctgt atcatatgaa aaaagccaaa gaaaagcgac
    41821 aaaagagcag gagttggctg gccgctgttt tgccgcagtc gcttttttct ttttagacgt
    41881 catacaaagt ttctgtatgt tcttttacta taacgatctt aatcttctaa agatttatat
    41941 tcaggaaccc atttagcaga ttcaactgct tctttgatat ccgtgatttc ttcacgattc
    42001 aagttttgtg cgacaactga ttttgcgaca gtttcagcaa tcgtttgaga aaattcagtg
    42061 atttttgcta ctggaggcaa gatagctgct cctggttttg ttacatcaac gattccgcct
    42121 aatgctcgac tagcttgaga aatgatttca gcatttactc gtgtagctgt tgaagcaatc
    42181 aaaccaagtc ctaaacctgg gtacatcaaa gcattatttg cttgaccgat ttggtaagtt
    42241 acaccattat attcaacatc agcagcaggg atacctgttc caactaatgc ttttccgtcc
    42301 gtccattcta ttaaatcttt tgcttttgct tctgccaatt ttgttggatt agacaaaggc
    42361 atgatgatcg gacgtggtgt atgagcagcc atttctttca cgatttcttc agtgaatgct
    42421 ccaggttggg tagaagtacc aatcatgatt gtcggatgga tcgcttttac aactgcttct
    42481 aagtttgtca attcatcagc attagtgaaa tctgagcgtt tgcgagcgaa tgggatttga
    42541 ccaggagtca atccttctgt atcttcaaac aataaacctt gtttatctac ttgatagaaa
    42601 tgttggcgtg cttcttcttc aggtacacct tgacggatca tctcatctaa aaggatgttt
    42661 gcgataccca caccagcagt accagcacca aatgtcaaaa ttatttgatc tttcaattgt
    42721 tcaccggata tattcaatcc gcctaataca cctgctagga caacaattcc tgtaccttgg
    42781 atatcgtcgt tgaaagtagt gatttgatct tcgtattttt ctaagatcgc tgcagcattt
    42841 cctcgtccaa aatcttccca atgcaataac aattctggga ataattcggt agctgattga
    42901 acgaattgat cgatgaattc atagtaagtt tcgccttcta cacgagcatg acgattgcct
    42961 aagtataagg gattattcaa taattcttca ttattagtac cagcgtcgat cgatacaggc
    43021 aaaacttgtg ctggattaat accagcagca gcagtataga ccatcaattt gccgatagcg
    43081 atgtcaacac cgttcacacc ccagtcgccc atacctaaga ttccttctgc atcagtcaca
    43141 acaatcaaac gaatgtctcg tccatctgcc gcgttcttca aacttgcttt gatgttttct
    43201 ggttcgtcga ttgaaagaaa tgcagcatct tgcggtttca agaaaatttc gttgtattgt
    43261 tcgattgaat ccgcaacgac aggatcataa acgacaggca tgaattcaac taaatgttcg
    43321 cccatcaatt tataaaacaa tgtccgattc gtattgaata gattcattaa gaagatacgt
    43381 ttttccaaat ctgtttgttt gcttaagtat tgaccataag cttgaacaga ttgttgttcc
    43441 agtgtttgga cagtacttgg aagcatacca gtgattccat attttgcccg ttcttctttt
    43501 gtaaaagctg ttcctttatt tagaaaagga ttatttaata agtttaaccc tgtaagcatg
    43561 aatgattcct cctaagtttt aatacaaacg aagtatagaa gtcagatgat gatatagtca
    43621 aaaagagcag gtatgataaa ttttatttat atgtaatata gccaaaagaa atcaaaatag
    43681 cagtatttgt tctttttata tcgacaatcc ttgcttgaat actatgcgta tctcttatat
    43741 gctagagaaa gaaaagtaga agaataaggg atagatggaa tggataaata ggatttctga
    43801 ggaaaaaagc acatgatagc gttgatagga gtcacctatg tcaggtgata aaaatacata
    43861 agtagaaaat taagaggagg aagagaaaat gaaagaagtt caattgatta gaaaaagcga
    43921 actatcagaa ggcggttgca atgcatgtgg cgtagtagaa gcgacaagct atacattaaa
    43981 attagattcc aatcaagcaa taatctctga actgacagta ggcggtcttg tggacagtct
    44041 ggcgcttgct gaaggtttta ctggagaaga tatttatgag atgttttcag aagtccgtca
    44101 gttaaaaaaa ggagaaaaat gcatagaggt tcatcatgag agcccgaatg tgaggttcaa
    44161 acgtggtgat aatgagatga tcttcaagaa tcatgtgtct gatcacactg aactatatga
    44221 aatcgtgaat caaatactgt ctgggatttt tgaattagga ccttatgagt tcaaggaaga
    44281 aaacggtaat ccaaaattaa atgaagaatg gcaagaaacg attgaaacac aaagaaacaa
    44341 tccacactta tttcaatagt cttccacagt atttcgtaaa aatgttgatg aaaaagaaac
    44401 accgtgaatc agaggtcgtg aaaaacctgc cctgcatcaa gtaataagaa cagccaaaca
    44461 aaaatagctc ctcctatttt tcgtttggtt gggcttatta ccgcagatgc aagtttttga
    44521 acaccgttta aggaagagac tgtgaagtca acgttctgac ctgagtatta gagagacaaa
    44581 tggcaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    44641 gaacaccgtt ttatcgagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat
    44701 tttgtgaaaa tggctttcca catttttgca taaatttgac ttaataccga gaaaatggct
    44761 tttgaacacc gtttattcaa aaaaagggac tttgacacta cttttgtcaa agtcccatcg
    44821 gttttttatc tatttttatt acaatcattt cttccagagt agtgacatct ggaatggctg
    44881 aaatgtaaac agattatttg cctgtatcaa tgtcgaagag taatataaaa agtgtaaacg
    44941 ctatcatatt gttcatcatt caaattttat agagagaagg cattgagatg gaaaaaacat
    45001 atcaagcagg tacaaatgaa ggaatagtag attttatcaa tatggaagat ttagaaatcg
    45061 cggcttcaca agtgattcca gctggtggtt atggttacat cagcagtggt gctggcgact
    45121 tatttactta tcaagaaaat gaacgggcat tcaatcatcg tttgattatt cctcatgtat
    45181 taagagatgt agaattaccc gatacaacta cacattttga cgaagaaatg ctgactgcac
    45241 caatcatcat ggcaccagtt gctgctcatg gattagctca tgtgaaggcg gagaaagctt
    45301 ctgcaaaagg tgtagcagat tttgggacga tctatacagc aagttcttac gcttcttgta
    45361 ctttagaaga gataagagaa gcaggcgggg agaaagcacc gcaatggttt caattttata
    45421 tgagcaaaga taatggaatc aatttggata ttcttgaagt ggccaagcgt aatggagcaa
    45481 aagcaatcgt attgacagcg gatgcaacag ttggcggaaa ccgtgaaaca gaccgcagaa
    45541 acgggtttac cttcccgctg ccaatgccga tcgttcaggc ttatcaatca ggagtaggcc
    45601 aaacgatgga tgctgtatat aaatcttcca aacaaaaact tagtccaaaa gatgtagaat
    45661 ttatcgctgc tcattctgat ttgccagtct acgtgaaagg tgttcaatca gaagaagatg
    45721 tctatcgatc attagaatct ggtgctggtg gaatttgggt atctaaccat ggtggccgtc
    45781 aattagatgg ggggcctgct gcgtttgatt cgttgcaata tgtggcagaa gcagtagata
    45841 aacgtgtacc aatcgtgttt gacagcggtg tacgacgtgg acaacatgtt ttcaaagcaa
    45901 tcgcatcagg tgccgatctt gttgctattg gcagacccgt tatttatgga ttgtctttag
    45961 gaggaagtac aggagtccat caagtgtttg atttctttaa aacagaattg gaaatggtca
    46021 tgcaattagc tggaacacaa acagtagaag atatcaaaaa aataaaattg cgtgagaatc
    46081 gttttattta agaaataaat gacgaaaaaa ataggagtgc ggcagatgat gccgtactcc
    46141 tatttttata gttcaaggat gtcactaata gaataatttg aaacgaaaaa ataaaattga
    46201 aatattgttt catacttaat aaaaaaggaa gaatattcat gtaaacgatt ttattgtttt
    46261 tttctctttt atacaaaaag ggtcataatt tcaagtaagc ggatgaattc atgaggattt
    46321 tttgcatact gtctctacta tacttaggtc actaagaaaa aggagtgatt tattatgaaa
    46381 aagaacatga ttgggacatt attactttca acacttcttc taggcggctt ggcaacacca
    46441 gcttttgctg agggtcaagc gacttcaaaa ggagatatta cctttactga accaacaaat
    46501 accgttgagc ctcttaaccc tactgatcct tcaaaaccag tagagccagc agatccggaa
    46561 aatccagcaa ctggccagac aggttcttta acattggatg tagttcctga attgccattt
    46621 ggtacacacg agattgaaag cggaacaaaa acgtatcaag tagacgcttc aaaaaacgat
    46681 acaccttatc tccaagtatc agatcgtcga ggtgtaggtg cagatggcca agcacaaggg
    46741 tggaacgtga cagtttcggt ttcagatttt gtaaacggtt cacaagtttt gcaaggcgct
    46801 gaattagatt ttggaacatc cactgttaaa agtacgtcag ataacgaatc cactggacca
    46861 actagtcaaa ctgtaactgg gttgagtaaa gcaagtgcag cgacaccaat atttacagca
    46921 gcaaaagatc aaggtctggg aacatggctt tctgtttatg atccagcaaa tatcacactg
    46981 aaagtgccga aagcagcagc tggaacattc acggctgatt tgacttggaa cctcgtggct
    47041 ggcccagtag catagagtat gaaataaatt caacaaactg cggtgaaaat actataggtg
    47101 aaggattttt taccgcagtt gttgttgaaa ggatgtggtg gacaatgaat caaagtaaac
    47161 gactgtttgt ttcgtttttt tctattttaa gtctattttt catttttccg tcaatcagcc
    47221 aagcaaagga ttcagcagga gactttggaa tcaaaccggt atttccagag aaccaaatag
    47281 ataaagcaat cggttatttt gatttattag tggcaccgga acaaaatcag acactagaag
    47341 taattatcag caattcttca gatgaagaac gaacatttga ggtctctgtc aatccggcgg
    47401 taacgagtga tggtggaacg atcgattata gtcaaaaaaa cccaacgtta gatgagacat
    47461 tgccgtttga tgtccgtgac gttttgctca ttgcgaaaaa ggaaatcaat gtatcagcac
    47521 atgcagaaac aactatacct atagaagtga aaatcccagc aaaaagcttt aagggacgtg
    47581 tattagcggg tattcatgtt tcacctaaag aagaagctga aacagaaaat gctacagaag
    47641 gagcacaaat caaaaatcgt attgcttata atctcgcagt cgttttacaa gaaagtcaag
    47701 agacgataga accggatctg aaacttttat caggagattt ggacgaggtc aacgcaaagc
    47761 caactgttca gcttcgtttc caaaatcctc agcctaggat tatcagcaat ttgatattta
    47821 cgagcaagat cttttatgaa aatcagcttt atattgaaaa tacgtctaat gaatttttag
    47881 ttgcaccaaa ttcgaatttt cacttgaatc ttgatttagc tggtgataaa gcaaaagccg
    47941 gcgattaccg cgcagaaatc atagcaaaat caggcgacag taatgaatgg cgatttacac
    48001 aaaactttac gatcaaaaaa gaaaaagcac aaaaagtaaa tgaaaattcc gtttttgcag
    48061 tacaagaaca atctttccca tggctttatg caggattggt tgctgcagtt ctagtgttat
    48121 ggttgatttt gctgtttttg tgggtccaca agaaaaagaa aaaaggagaa acaacatgat
    48181 gaggtgattt cgttgaaaac atcgatctta ttgggaggga ttattgcaag tttgctgttc
    48241 ttcagctggc aagagccagt ccaagcagat accaaaagtt caggtacgat tacattttat
    48301 gatctaagtc cagttccgca tccaagtggt tcagtcaatg gcgcatcaaa acagcagaca
    48361 cagctaccga tttataaaga atctaatcaa catggcgtat tcccggagac gaatgaagaa
    48421 aagatccgtt ttctttattt gatcattggt atagaattat ggcttcttgc gtggttgttg
    48481 ttatggagaa gaaaggaaaa ggaggatgaa catgttgcta caaaataaat tttcattttt
    48541 tcgctccttc ttttttactt cgctttttgt tttaagtata tttatctttt caccttcggc
    48601 agaagctgtt ggagcaacgc ctcctgccat ttcttatgat ccatacacgt atgaaaatat
    48661 cgtacctcca aatggtggac gtagtgcagt caatggcggg aagcttgtcc aactaactgg
    48721 ggctaaccaa ttgcctaaat tgactgctac ttatttgaac gatggttcaa atgatccttg
    48781 gaaaggtggc acggtccgtt ttcattggga aagccatgtg aaactaacaa atgtacttga
    48841 tttggtgaat atcactgcac aaggatttgc atttgtggcg atcatcaatt tgccggaaca
    48901 tgtatcaagc agtgatgtat taaaagcaat tgactggaac aacgcctact tgtatattgc
    48961 cggtgccccc atcaaggtta ctagcggtag tttattatca gcaggaagcc ataccttgcg
    49021 ttttgggatg gggtcgtggg atacaaatac tctattggca gatattattg ctattattac
    49081 gcgaggcgaa ttcaacgtgg acgatatccc gcttcaattt gatgttacag ctaatgtcgc
    49141 gaagatgaca gaaaacggag ataaatatga tacgagtcca aacaaaattt tgaccaaggg
    49201 taaattacaa ccttctatgt ctaaaaaggc cgttttttct gttgattttt atgattcgaa
    49261 taatattatc caagatcgta tgttcaattc gattttagct ccagctgcag gtagatttta
    49321 tcctaaatta actggcggaa acttgaatcc aggagcatat gcattttctg caagtgcaga
    49381 gataaatacg tggaatagtt acatctcaac aagtgattca acaggaaaat ataatacatt
    49441 tgctgatacc acagaatacg tggatggaaa taaccagaac cttccaggct ctaccaatag
    49501 tcggacattg acgatggggc tgactgaagg acgttttgat cagttgccat ttagtcgctt
    49561 tgatcgcgta gtcaactatt ttacaggaaa aaacgttaca caaggagcaa tactgactca
    49621 tactccagca agcacaagtg gattgaatca gacagccaat atcgtgtaca gtgggaaaga
    49681 tgcgcaaggc ggattgcttt ctcctgttgc tttaaaggta ttggagcagt acaagctaga
    49741 cggaacggtt ttaccaacaa acttaacagc cgatagtcag tggggaaagc tcctttcttc
    49801 tgcatcgtac caagtcacgg ccaattggtc agcaactgaa ctaaaaaagg gttcgatcca
    49861 ttacaggctt tattcgaaag gaacccaaaa attagcgaca ggatggacag atcaactttt
    49921 ccaaacgatc caatcaaata acgggggtgt aaatacagct acttctacac tacctgcatt
    49981 ggcttcaggg caatattatt ttgattatcg cttggtggac gatgtactta ctaacatgta
    50041 tccgtctttt gcgtacaaat ggcagtctga acaagctgga atcaccactc ttcctcaaat
    50101 aacagtggct aattttccat ctgtgagtgc agatagtcag ctaaaaaacc ttagcagaca
    50161 acctgagaca ggagatcccc tgtctgctct atcaggagat acgattcaag aaaatgtgac
    50221 attcacgtta acaaaatctg gggatgcgat aaccgacaaa aaaatcacga tctcacttcc
    50281 tgaaaatact acttatatca atggttcctt aaaattaaat ggtacaacta tcgcagatac
    50341 cggcattcaa caaggagttt ctgtcccagc agatctattg agcaaaatag gagataccat
    50401 tcatcttact tacaactatc aattaaatac tgtagatact tctgtacaat ccgtcagcat
    50461 actgacaaag gcagctgtac tttccagcaa tattacatta gcagatggtg ctaagcttcc
    50521 taacccagtt gtccaaacat ctgctaaaac aattcttgtc cccaaacaag aattaacatt
    50581 agttaatgta ccagatgatt ttacatttgg taacgatctc cccaaaccgt tgaagacaag
    50641 ttattatgaa gcaaaaggcg atttttcttt tgatgtgcgg gatactcggc ttccaagcac
    50701 gtctccttgg caactgacag ggacattgac ttctttattt aagaatgatc aaggtcaaga
    50761 attaagcgga acaaaattat acttcaatca ttctggatca aaacaattga ttcagcaagg
    50821 tcaaaacacg ttgatttatg agagtgatgg aacagctaaa ggagaggttc tcgttgactt
    50881 tcccgatacc gatggtttac tcttagaggt aaatagcagt acgaatgctc aacctggcgc
    50941 aacgtatcaa ggcatggtca catgggaact gacagctggg ccaaccagct aagtgattag
    51001 aatttgtatg gatctgtgat aactgtcaca gatcctcttt ttcaaggatg agaaggaaac
    51061 ttctgctgtt aaaatcagaa atgcttggag gagtggactt ggaacttttc agtttgcttg
    51121 aaaaaaatga acaacggcaa atcaaacttt tccaactttt attagaggaa aaaggagaga
    51181 tttccgttaa taacgtactt acccgcttat cagttgatcg ggctaccttg aaagaagatc
    51241 tgttttattt acaagctaac ttggaaaata tcaaacaatt ggaaattgtt atccaagaag
    51301 ggaatatttt attaatcaga catggaaata tagcagcagt cgatgtttat tatcattgct
    51361 acttgcgcta ttctacaaaa tatcagatac ttctttatct gttggaaaat ggctcatttg
    51421 atcggcagaa acttgtcatg gaacttaata tcagttcggc tactttgtct cgcagagtga
    51481 aggaattaaa tgattcttta aatgagtttc atctgaaaat aaaaagcggg cggctgaccg
    51541 gtccagaaag tcaaatttgt tatttttatt tccaattatt ttggtttgga cgtccttatc
    51601 ttgaaaacaa aaaagaatac agtgatttat caggaaacac ttttttagat ctgctgcaaa
    51661 aagagtttag ttttactatt acagaagaag gacgattgaa atttgaaata tggctttcca
    51721 ttatgaagaa gcgaatgcgc tgtacgaaaa aatccaaacc agattatagc aatcttcctg
    51781 ttggattgtt tcaaacgaca caatttttat tggacctcca tacatttttg acccgttact
    51841 tctttcaata tgcctttcct tggaatcaaa atgaaacgtt ggttttttat cttttcatga
    51901 tcagtaactt tacattagat acacataact cgcatgtcca ggagtttttg ataagcgaaa
    51961 aatacaaaga cgacgtagta gctcaattga atcgaacgtt taaacaatcg atagaagaat
    52021 atttctcttt ttatgttttt ccagaagaga tttcgcaaaa gattgcgttg acagtgatgc
    52081 aaaatcacgc tcattttgcc tattttagag gatggatgaa tatttttggc caagaaggat
    52141 taaaacagcg gttaactgaa gtagaagata aacaattcct ggttttatgt gaaagattgg
    52201 tcagacaaac atttgctatt gttgatttta ctgaagtaga cgaggaaaat gcccgctttg
    52261 aattatttgc tcgctatgca tctattttgc ggacgctgat caagcagtta gaattacgtc
    52321 tgcaaattgc ttatgatctt ccttatgaaa ggctaatggc ggatatcgtg aaagaaatca
    52381 tccaggaaca attgctgaat acgatcaaat atgatttagt cgaatacgag aaagaaaagc
    52441 agtatgatat cattttgact agccaattga aagagtaccc gtcacagaag tccgctaaag
    52501 tttttgtatt cactagcaac gaatataatt atgatttccc ctatttgaac caatttttaa
    52561 aagaatgtta tttagaaaaa ttgaatttaa ggatgaataa aacatgaaaa tcgtgatcat
    52621 tggtgcttcc catgcaggca tcacagctgc cctaaatcta agaaaacttc aaccgaaagc
    52681 agaagtttta ctgatcgatg aagatcataa agatggacta ggctatgttt caaatggaat
    52741 caacctttat ttaaaaggaa agatacgtag tttagctgaa gttgcccata acatgcggac
    52801 tcttcaagaa agtggggcaa aactgatcac cgaatggaga gtaactgaac ttgatccaga
    52861 caaacatcag ctcatcctcg catccaaaga aggaaaaaac gagaccataa cctatgataa
    52921 attaatcgta gcaacaggtt cctctcctgt caccttgtat aaacaaattg aagctgaaaa
    52981 tgtctacacc tataaaaatc tagtgcaatc taagcaagta cttgccgctt taaaagaagc
    53041 aaaagaagta gtgatcttcg gtgctggtta tattggattg gaattagcag atgctttgag
    53101 aaataaagga tacattattc atctagttga ttatatgccg aatgttttat caagatattt
    53161 cgataaggat atgatcaaca gttttcaaaa tcagctgcaa actaagcaaa tcaattttta
    53221 tccaaatgaa ttcttgatcg attggaaaaa atcagaagag aaagtagtat ccgtacaact
    53281 tctatctcaa gcaataaagg cagatatggt cattttttct gcccaaactc gtcctaatac
    53341 gacattgtta aaagaaaaag tggctttgta tgaggatgag actgtgatag tcaatgaata
    53401 tctgcagaca agtgatccgg acatctatgc gattggagat atcgtcccag tcagttttga
    53461 caaaaataaa cggcatctct ttttaccttt agttactcga gctgtacata tggcaagagc
    53521 agtagcgcta actttgagtg gtcagccaac cgcttacgac ctcagacaaa agataacagc
    53581 agcagtcatt atagactact ttttaggaac tgtagggctg acagaagatg aagcgccatt
    53641 cttggaacaa aataccggtt cgtgttcagg agaatttgat ctatttccac aatacgatga
    53701 agaaaacaaa acagtaaatg caaagctgat ctaccatccg gatacattag aaataattgg
    53761 cggacagctg ataagccaag aattcttatt atcagatttg aacctgcttg cggatatcgt
    53821 gaaacacaaa actacgattc cacagctagc agttgaggat tttggatttc tgtctgaaca
    53881 cacctctcgt tttcactacc tcaatgagtt agcttttaaa gtactagcta agagagcaaa
    53941 tagcaataga gtagataaaa gactgtgaga aatatcacgg tcttttattg tgtggggata
    54001 taataaatat taatcaatcg agaataaaaa attcatataa tgaaatagcg gaagaatttt
    54061 ttgagcataa tattcgccaa aaatttatca agtgataaaa ttgttgtata aaatgattat
    54121 ttcaggagga ggagttaaat gtttttagca ttaaatgaaa ttatgcattc aaagttacgt
    54181 tatgcgttag ttgcaggggt gatgtttttg atcgcctacc tggtattttt tttgactggg
    54241 ttagcttatg gcttagctca agataatcga acagcagtcg acaagtggga ggcagattcg
    54301 attgtgcttt cgaaagatgc aaattcaaat ctagggatgt ccatgattac taagaagata
    54361 gcagaagaag tcgaaggtgg gaaagtggcg tatcttgccc agacacctgg agtcgtgact
    54421 agtaaagaca gtacagaaga aggaaaaatc aatgttagct tcttcggtat cgataaaaat
    54481 caattcatca tgcccaatct tgttgaagga aaagcttttg ataacgatga tgaggcagta
    54541 ggcgatatta gtttgaaaga agaatatggt ctagccgtag gagatacagt taagttatct
    54601 ggtagtgaca agacgtttaa actaactggc tttacggatc atgccaaatt caatgtctca
    54661 ccagttctct atacaaccat caatgcttac caagagatcc gcttcgaaaa agaagataca
    54721 agtgaaaatg cacggattaa cgcaatagtt gtcagaggta aaatcagtaa tttacctgaa
    54781 gatttagaac agatcaaaat ttctaaattc atcaatgaat tacctggata taatgcgcaa
    54841 gtattgactt ttggatttat gatcggattt ttgatcgtta ttgcggctat tgtgatcggg
    54901 attttcattt atgtactgac gatgcaaaag attaatatct ttggtgtaat gaaagcacaa
    54961 gggatcacag gaggatttat tgcgcgttct gtagtggcac aaacattcat tttatcattt
    55021 gttggtattc ttcttggtct attaggaaca gtgggaacat cccttgttct acctgatgcg
    55081 gttccattcc aaagcaattg gctgtttttt ggcgtcatta gcttgttgat gctggtagta
    55141 gctgtgttag gcgcactatt ttctgttcgg acaatcgtaa aaatcgatcc gttgaaggca
    55201 attggataag aaggaggaag agcatgaaag caatagaatt taaagaagta gaaaaaagtt
    55261 tccaagatgg cgaccaagta gttaaagcat tgaaagaaac aaccatgagt atcgataaag
    55321 gggaatttgt tgcaatcatc ggtccttctg gttcaggtaa aagtactttt ttgactttgg
    55381 caggcggatt gcagacgcct agcagtggct ctgtatttat caatgatcaa gaattcagta
    55441 atcaaaaaga aagtgaacgc gttaaactac gttttaaaga aattggcttt attttgcaag
    55501 cttccaatct ggttcctttt ctgacagtaa aaaagcagtt attattagta gataagatca
    55561 aacatgaaca tcgtcaaaaa gaagcaaaag aattatttga gcagcttggc gtggataagt
    55621 tgatcaacaa gtatccagaa gaactatctg gtggagaacg gcaaagggtc gcaatcgctc
    55681 gtgcattgta caatgatccg tccattattc tagcagatga accaactgct agtttggatt
    55741 cagaaaaggc acgagaagta gtcgatatct tggcaaaaga atcaaaagac aaaaataaag
    55801 caacgatcat ggttactcac gatacacggc tgattgacaa atgcgataga atatttatga
    55861 tggaagatgg tgtattgaaa gaaaaagaat aaccaaaaag caggtggaaa aatggtccat
    55921 cgatacaaca aagatacaca gcaaaaaatt ttgaaagaag cgactgactt gtttatgtcc
    55981 aagggatatc tcggcacttc aacaagagag atcgcacaaa aagttgggat cacccaaccc
    56041 aatctctatc attatttcgg tgataaagaa aaactatata cggcagtttt agaaaaccac
    56101 ttaaaagatg ttggaaaagc tttgagagaa atcgttcaaa caagcgaaac gggatttcaa
    56161 gtaaccttga caaaaatggc gcagtttttg attgagacac atctggtcga tttgtttctg
    56221 atgcttcacg atcttgaaag caatctttca aaggaaacaa gagatcatct tttctttcta
    56281 tggaagaaaa attatcgtga accttttgaa gaaatctttt cagcaaacca atctgtgcta
    56341 agaaatggga tttcaaaaga aatcgcagca aggcattttt tcttagtgtt agcaccttac
    56401 atcactcggt cgaaaagacc tgtggaagaa ccgctaaatg tggcgcaatt gatcgattta
    56461 tatttgaatg gtgtattagg agaagcgtaa agctgttata tagggagaaa aatagttagg
    56521 tgaagaagca agatatgacg aagatcgtta tatcttgttt tttttatata ggtagttttt
    56581 cataaataca aatttgttat tctctcatga ttatcagggt atatttttat ttattatgtc
    56641 ggtgttccag gaagtgtttt aatttaataa cgaagaaatt aattgtttgt agaatgaagg
    56701 aaactattta ttgggtagat gaatcaccac gaatagtcaa aaggagattt caggatatgc
    56761 caaaaatgaa aaaaatcatt ttagcagtaa tgttattttc tacggttata tcttttacag
    56821 cccctttttt gcgtacttaa gctgatttta agttttgacc cttagtctgg atctacgagg
    56881 tgagagtcaa gaatgaaaaa aataattgga gcttttgtat ttgcaatcat tatcattatt
    56941 atctgttttc aaatagatgt ttttggtcaa aaaaagatag ttggacaaac ggtcagcagt
    57001 acgaacagta cggttacaaa gacaaaggaa tcatttgatg atacagaaca agagacatta
    57061 atcaaaatcg gaaaaaatga ccgtacacta tatacagatg actcgctaac taccccactt
    57121 gcaactataa acggcggaga gctggcggag tttctttctg aaacaaaaaa tgcttatcag
    57181 atcaagacaa atgatggcta tactggatat ttagccctcg aagatggaac caaagtcaca
    57241 aagaatatac aaacaaaacc ggaagagcta tctgatgcag tgattgtatt agatcctggg
    57301 catggcggaa atgatactgg ggcattaagc aatgatgaac aaacagaaga aaaagatata
    57361 acattaagta cagccataaa agtaaaaaag gcgctagagg atgctggagc aacggtttat
    57421 ttgacccata ctacagatga attagtacag cttggagata tatgcgacta cagtgaagaa
    57481 aaaaaggcag atgtctttat cagtttacac gcagactcta cggaatatgc gaatgaagca
    57541 actggaatca cgacatatta ttactatgga caagaggaaa cattagcaca gacaattgct
    57601 gactccttca ctgatctgcc tctggattca agaggaatct ccactgggaa ctatcaagtt
    57661 cttcgagaaa atcttcaacc ttctatttta atcgagatgg gttatatgaa taatgatagt
    57721 gatttaaagg aattagtaac agacagttat cagcagcaga ttgctgcaag tttgacacaa
    57781 gcattgacca cttattttca gtaataaata agcccagcca aacaaaaata gctcctcata
    57841 tttttcgttt ggccgggctt attatcgcag atgcaagctt ttgaacaccg tttaaggaag
    57901 aggttgtgag cctgccgttt aactccgcgt cacaaggagc aatttcaaaa aacagcttct
    57961 catgtttgat gactattgtg acttgtgacc gaggagttgg catgagaaca ccgtttattc
    58021 ggaacaaggg actgtgacat gacttttgtc acagttccat tattttttta gcagcttcaa
    58081 agctttttct gtattggcaa aatgaagttt ggcatatttt tcaagcatag gcatgccgcc
    58141 tttctccaat agttttgccg ctacttggtc agatttcgtt ccagctcctg atggaagggt
    58201 gattccagct tcagctgatg ctttgtgtaa ctcttccaaa aagctggcac gactgatgat
    58261 agaagcagca gcaacagcta aatgatattg ttctccttta gtaacgaagt acagtttttc
    58321 ttgtaattga tttttttcta aacgcgcata ttttttaaaa tttgcttccg gcgtaaactg
    58381 atcgatcaaa atcgcttctg gtttttctgg ctcgattttt tttagcagca aatggatcgc
    58441 ttgattgtgc aaagcgactt tcatccgaac ggcattgtat tttggttgga tctcattgta
    58501 tttttctgga gataagacaa gcagtttata ggggatggtt ttttttaaga tgtcagcaag
    58561 ctggatgatt tggctatctt ttaactcttt tgaatctcta acaccaagtt tacgtaattc
    58621 tgcaagctga tcacgtttca cataagcagc acatactgtt agcggaccaa aatagctgcc
    58681 atttccgacc tcatcactac ctaaaacgga taattgactg atattttttg gcaaagaaga
    58741 ggctgttttt gctggcttgg cttgtttatc ctgtgcctcc ccccatttat cagcttctat
    58801 tgctgcattc gtaccttgaa acatcacttt tccggatgta taagcggtaa tggtcgtccc
    58861 gtcttttttt gcagcaaagc tagtataagg aatctgttta tttaacaaat aagagcgata
    58921 gtatgctttc atttgactaa gttggtcgtt tgttgctttg ataatgacgt tgctcataaa
    58981 attctcctcg tttttataca taaaactata ccgcaactca cgacttttcg ttttctaaga
    59041 gattgcgaga catagcattt ttttaaagtt tatcatataa tagttaagta tgtgaaaaat
    59101 atttgtggag aacggtgaaa gaaccaactt catggtacac taaataaaac tttcatcaaa
    59161 taggaggaaa tgattcgtat ggcgcacgaa aaaacacgct acaaagcagt gattgccaac
    59221 caaacatata ctattatcgg acgggaaacc aagcatcata tggatatcgt aacgaagctg
    59281 atcaatgaac agttagcaga attgaaacaa ttatcaccac aaatggataa tgaacaagca
    59341 gcaatcttga tggctgtcaa tgcgctttcg gatcaattga agaaacaaga aagaatcttg
    59401 gagctggaag aagaaacagc agaattaaag aaaaaaatga tcaaatttac agagcttgaa
    59461 aatcgtgtga aacgcattga agcaatcgag aacgaagctc gggaagtatt gaaagaaaat
    59521 ggtcaagcag atcataccat taaaaatcat gtggaagcac aacagatttt aaacgagaaa
    59581 cgaaaaggac aaattaaaca aaaatcttct aattaagatc cttttatcaa aataagaaaa
    59641 atttaaaaaa gttagaagag aaaggaacgt agcatgctga gtttgctgat tttattttta
    59701 ttgctaattg cgtttttttc tggagcacgt cgcgggtttg ctttgcaaat catattcgcg
    59761 attggatatg tattgtcatt tattgctgcc cagcattttt acaaaccatt agcaagtcat
    59821 ttggaattat acattccata cccagctgtc accccaacat caaagttagc attttttgat
    59881 caggtatttg cttttcacct agatgaagct ttttatgcag gaactgcttt tctgattatt
    59941 ttgctaattg gctggctgct tacccgattt gtgggggttt ttgtccatgg attgacgtat
    60001 gtgccgatct tgagacaggt agactggatt gcaggaggca tcctgtcact aatcatggct
    60061 tacgttacta tatttttgat tttgcagtta cttgcctttg ttccattaga tgtggtccaa
    60121 aatcaattcg gcgagcatag tttcgctcgt tttatcgttg agagaacgcc atttcttacc
    60181 aacaagatgt atgagctttg ggtaacgaat attttgaatt aaggaaaata gtgctggaaa
    60241 atatttcgtt ttttgtacag agtagtttat ttaagaaggc tgcgtagcgt atgtccggca
    60301 cagctctttt ttcatagtga aagataaggt gataaaatga ataaccgaat ccttgaaaca
    60361 ttggaatttg aaaaagtcaa acagatggtc agacaatttg tagtgactgc acaaggaaaa
    60421 gaagaactgg cagaattggt accagtgagt gagaaacaaa cgatcacaaa ctggcttcaa
    60481 gaaactgagg atggattgaa agtgcaacgt ctgcgaggcg ggatccctat acctaaactt
    60541 gaaaatatcc gtccccatat gaaacggatc gagatcggag cagacttgaa tggagtggag
    60601 cttgcacaag tttccagagt attgtctacg acaagcgaat tgaatcgttt cattgatgat
    60661 ctttctgaca gtgaaatcga atttgcacgt ttgtatatgt gggcagatca gttagtcacg
    60721 atccctgttt tgagccgccg tttaaaggaa gcaatcgatg aagacggacg cgtgactgat
    60781 gacgcttctc ctgagttaaa gagcataaga cagaacattc ggcgaagtga acaagctgtt
    60841 cgtgaacagt tagatgggat cgtccgtggg aaaaatgcaa agtatttaag tgatgcgatc
    60901 atcaccatgc gaaatgaccg ctacgttatc ccagtcaaac aagaataccg cggtgtattt
    60961 ggcggtgtag tccacgatca aagtgcttca ggacagactt tatttattga accaaaacaa
    61021 gtggtggatt tgaataatcg tttgcgtcaa taccaaatcg ctgaacgaaa tgagattcaa
    61081 cgtattttaa gtgaactttc tgctgaactt gttccccatc gtcaagaaat catccacaat
    61141 gcttatgtga ttggtaaaat ggatctgatg aatgcaaaag cacgatttgg taaagaagta
    61201 aaagccatcg tgccgggaat cagtgaagac aatcatgtcg tcttgaaaca agcaagacat
    61261 ccactgatcg atcaggaaaa agtagtttct aatgacatca caatcggaaa agactatcaa
    61321 gccatcgtca ttacaggacc taacacaggt gggaaaacga tcacgttgaa gactttaggt
    61381 ctgttacaac tgatggggca agcaggatta ccgattcctg caggtgaaga aagtcaaatc
    61441 ggtatttttg aggaagtatt tgcggatata ggagacgaac agtcgattga gcaaagtcta
    61501 tcgacctttt cttctcatat gacgaacact gtagatattt tatcaaaagt caatgaaaaa
    61561 agtctggtat tatttgacga gctcggtgca ggaacagatc cgcaagaagg tgctgctcta
    61621 gcaatcgcaa tcttagatga tcttggtaaa aagtctgctt atgtgatggc aacaacgcat
    61681 tatcctgaat tgaaagttta tggatacaat cgggcaaata cgattaatgc cagcatggag
    61741 ttcgatgtgg atacactaag tccaacgtat cgtttgctga ttggcgttcc tggacgaagc
    61801 aatgcgtttg aaatctctag ccgattaggt cttgatacag aagttattga tgaagcgaag
    61861 cagttgatga atgatgagag ccaagattta aacgaaatga tcacagattt agagaatcgc
    61921 cggaaaatgg cagagaccga atatctggaa atgcgtcatt ttgtttctga ggcacaagaa
    61981 cttcacgatg atttgaaaga agcttacagc tatttctttg aagaacgtga aaaagaaatg
    62041 gaaaaagcaa agaaaaaagc aaacgaagtc gtgtcagagg cggaagaaaa agcagaaaaa
    62101 atcattgctg atattcgtaa aatgcaacag cagattgggc aaggaaatgt gaaagagcat
    62161 cagttgatcg atgcaaagac ccaattagca aatctacatc aagaagaaac tttgaagaaa
    62221 aataaagtat tgaagaaggc gaaagaacaa aaaacgttga aaccgggaga cgaagtgttg
    62281 gttacgactt acggccaaag agggacgctt ttacgtaaaa acgggaatca gtggcaagta
    62341 gaaatcggta tattaaaaat gaatgtgtcc gaagacgagc tgacgcctgt tgctcctcaa
    62401 aaagagccga cacaacgagt tatccatgct gtacgatctg aatctagtag tcacgtgccg
    62461 aatcaattgg accttcgagg aaaacgatac gaagaagcgc taagtgaggt agatcaatat
    62521 ttggattctg ccattctagc tggttatcct caagtgacta ttgtccacgg aaaaggaaca
    62581 ggcgcacttc gcaagggaat tactgattat cttaaaaacc atcggagcgt caaaagcttt
    62641 gagtttgcac cggcaaacca aggcggaaat ggtgcgacaa ttgttaaatt taagtaaagc
    62701 ttactaaagg taagcagatg gttcgctatc caagtataga aatgctatac taatcataga
    62761 ttttaaaaat ggaggtcttt gatatgtcac aagtaattac agataagaca tttaatgaag
    62821 aaacagataa aggacttgta ttgattgatt tttgggcaac ttggtgtggt ccatgtcgta
    62881 tgcaagcacc gattttggat cagttggaac aagaatatga tgaagaagaa ttcagaattg
    62941 ctaaaatgga tgtggatgaa aatccagaaa ctcctcaaca attcggtatc atgagcattc
    63001 caacattaat gttgaaaaaa gatggtcaag tagtagaaaa agctgttggt gttcattcaa
    63061 aagaacaact acgtcaaatg atcgatcaat atttataaaa acttacagca aaaataagct
    63121 gagggtggga ctgaatccag ttccgtcctc ggtttttttg cggttgagtt aaggttattc
    63181 aaattaatat tttttgagta taattacgtt gtcaggctgg attgtttttt tgacagacat
    63241 gctataataa ctttaattga atatgaaggg gagtaccaga tgaacgaacg aatcaaaaac
    63301 aaattagctt tacttcctga tcagcccggc tgttacttga tgaaagataa aaatggaacg
    63361 atcatttatg tcggcaaagc caaaatatta aaaaatcgtg tccgctcata ttttactggc
    63421 agccataata cgaaaacgga acggcttgtt agtgaaatcg aagactttga atacatcgtt
    63481 acagaatcga atatcgaagc attgctctta gagatcaatc tgataaagaa aaatgatcct
    63541 aaatacaaca ttatgttaaa ggatgataaa acctatcctt tccttaagat aacgaatgaa
    63601 aaatatcccc gtttggtgat tactcgtaaa gtactaaaag acaaagcact gtattttgga
    63661 ccatatcccg atgtcggtgc ggcgaatgag acaaagaaga tcctcgatcg attatttcct
    63721 ctgagaaaat gcaaacctag tcagacgaag gagccttgtc tttactatca tttgggacaa
    63781 tgtctgtgtc cttattattt cgacgtagat ccgaaagtct atacgaaaat cgttgatgaa
    63841 gtgaaaaagt ttttaaacgg aggacacgaa aaaatcgagt cagagatcca tcagaaaatg
    63901 gaaaaagctg ctgaaaacat ggagtttgaa aaagctgcag aataccgaga ccagatccgt
    63961 gccattgaga caatcatgac tcgccaaaaa atgacaaata ctgatttact ggatcgagat
    64021 gcatttggtt atgcgattga caaaggatgg atgtgtgtcc aagtgttttt cgtaagacaa
    64081 ggaaagctaa ttgaacgaga tgtttcaatg tttcctttct ataacgaagc agaagaagat
    64141 ttcttgactt acctcggtca gttttatcag gaaaatgagc atttcattcc taaagaagtc
    64201 ttgattcctg atacgatcga caagcccagt gtagaagctt tgttagctac gaaagtgctg
    64261 caaccaaaac gaggagaaaa gaaaaaatta gttgaattgg cgaataagaa tgcctcagtt
    64321 gctttgaatg aacggtttga tctgattgcc agaaaacagg aacggacgat cggagcagtt
    64381 gaacgtttag gaaacgcgat gaatatcccg accccaatac gtatcgagtc ttttgataac
    64441 tctaatatca tggggacgaa tcctgtggct gcgatggtcg tattcattga tggaaaaccg
    64501 gcaagaaaag aatatcggaa atataaaata aaaacagtca acggaccgga tgattatgca
    64561 tcaatgagag aagtcatcta tcgcagatat tcacgagtga ttcgcgaagg gttgccttta
    64621 cctgatttga tcttgatcga tggaggaaaa ggacaagtag atgtggcaaa agatgtctta
    64681 gaaaatcaat taggaatcga tattcctatt gctggcatgg caaaaaacga taaacataaa
    64741 acaaatgagt tgctattcgg tatagatttg gctgtagtac cgcttgagcg aaattcacca
    64801 gagtttttct tactccagcg aatccaagat gaagtccatc gattcgcaat cactttccat
    64861 cggcagctac gcagtaaaaa cagttttgct tcccgattag atgaaattga agggttagga
    64921 ccaaaacgaa aaaaaatgct gcttaaagag ttcaaatcgt tgaaaaatat cacagcagcc
    64981 acgacagaag aattacaaga aatcggactg ccgaaaaatg tcgcacaaaa cgtatttgat
    65041 aaattacatc aggaatgagg aaagggcact ttacaaagaa agtaaagtgt cctatcattt
    65101 tatgtacaac aaaaagagcg tttacgtttt gttggtaaat aataaatcgc ttacgtctgg
    65161 tgtctaagga tatatgtgat ttcttgaaga aggagtgaag aaatgttaga agtcaaggat
    65221 cttgttaaaa cttttgggaa ctacacagct gtcgatcatg tctctttcca aatccccgat
    65281 ggaaaaatca tggggctaat tggccaaaac ggggctggga agacaacgac ttttcgtttg
    65341 atcttggatt ttttgacaca agaccaagga gaagtgttat ggaatggcca tcatcttggg
    65401 gagaaagatt atgatgtcat cggttatctt ccggaggaac ggggacttta tccgaaagta
    65461 acgattcaag accaactgct ttattttgca gaacttagag ggaaatcaag aaaagagatt
    65521 gaaccaaaaa tcgatttttg gatggaaaaa tttcaggtaa aagggaaaaa gacggataaa
    65581 gtaaaatctt tgtctaaagg aaatcagcaa aaagtccagc tgatcgccac gttaatccat
    65641 gaacctaaat tgatcatttt ggatgagcca ttcagcgggt tagatccggt aaatgctgaa
    65701 ttgctaaaag atggaatatt ggaattgaaa aaacatggtt catgtgtcat tttttctagc
    65761 cacaatatgg ataatgtaga aaaaatctgc gatcatttga tcatgttgcg aaacggaaaa
    65821 atggttttga atggaaaagt acatgagatt cgtgaatcat ttggccgtac gaagttattc
    65881 ttggaatctg gtttaagcca acaggaagta gaagaaatcg aaggcgtgaa aaaagtgatc
    65941 cttcatgaag acaatacgtt agagattacc ttagaagatc ctgaagctgg gaaagaaatc
    66001 tttactcgtg cgactcagtt cggctacatt cctatgttta accagcaacc gccaactttg
    66061 gaagagattt tcaaattgaa agcaggtgaa atcgatgcgt aagttttgga ttattaccaa
    66121 agatgtctat ttaaaaaatg ttaagtcgat ttctttcttg atcatgatat tagtcccttt
    66181 tatcatgctg ggtatcattt atgtagcagg aaactttgct caacaaaata gtgatgtcaa
    66241 taaaatcggc gtattggctg ataatgagca aatcagtcag caaatgagcc aagtcaaaac
    66301 agatgatttt gagttcaaag cagttgattc tgaagaaaaa gcacaaaaag agctttcgga
    66361 agaaaaaatc gatgcgtatt tagtagtctc aactgagaat gataagataa atgggatgct
    66421 ttatagcgaa aattcattag gacaaagtac acaactactg atacaacaac aactgactgg
    66481 cttgcaatcg atgcttcgag caagtcaatt aggcatttca ccagaagaag tagctagctt
    66541 gagccaacaa gcaagtttga ctcgacaaaa agtcaatttt gattcaaaag gaaaaatgac
    66601 agttggagaa gataactcga cagtccaata tgtcgtaagt tatgtagcaa cgattgtctt
    66661 gttcattatt attttgacgt atgcgcagat cattgcacaa gagatcgctt ctgaaaaagg
    66721 cacgcggatc atggaagtga tcctgtccag tacgactgca caaaagcatt tttacggaaa
    66781 actaacaggt gttttacttg ttgcattaac gcaaatggca ttatacggta ttatttttgg
    66841 tataggatac agtcaattca aagatatgga aatggtcaaa aatatattag acggtatctc
    66901 attggataac ttgattggac cattcttgtg gtattctctt ctattcatga tctttggcat
    66961 tttgattttt tctgttttag cagctttatg tggctctttg gtcaacaaag cagaagatac
    67021 agcaaaagca attttgccag tgacttatct atctctaggc ggatatatgc ttggattgat
    67081 actaggagct tcagatccaa acaatatcgt tattcggatc acttcgtata ttccattctt
    67141 atcttcatat attatgccgg ttcgcttagc aaatgagaca gtcggtatgg gtggagcatt
    67201 gatttccttg ttggtacttg tagccgtaac attcttattg atgatcttgt ctgcaaacat
    67261 gtacaaatcg aatgtactcg tgtatagcga aggcggatta tggagttcat tgaaacaatc
    67321 gatttcaatt atgagaaatg aacgaaaaaa agcataaaat atagaaaaat atagaaggaa
    67381 gctggacatt tattgttccc agcttctttt ttgtatagac ctatttctat ttttttatta
    67441 tattggatat atatattcat tgaaaataga gcataacaac tttataatgt tgagtatacc
    67501 aatttttgga ggcgttttaa tggaccgcta tttagattta ctttcagaga agttccctac
    67561 aacggaagat gtcatcacgg aaatcatcaa tctcgaagca attttgcagc ttccaaaagg
    67621 aacagagtta tttttgagcg atatacatgg cgaatttcct gcttttgatc atattctgcg
    67681 tatcggttca ggaaatctta aagaaaagat caaagacctt ttctctgaac aaatgacgga
    67741 aacggagatc agccaattca ctatttttac ggcttatcca gaatatgtgt tgacgactga
    67801 ttggtacaaa aaacaagata aatcccagct gatccatcgt ttgatcgatc ttttacggtt
    67861 tacgacagtc aaatacactc gatcaaaagt tcgaaaagga ttgccgaaag aatatagcta
    67921 tatcattgag gaactcttgt atatcgatga tcgtatcaac gggaaaaaag actatgtaaa
    67981 aaaaatcatt gaacaacttg tcttgatgaa ggaagaagaa aaatttttaa caaaacttgc
    68041 gcagacgatc caaaaatctg tcatcgatca tttgcatatc gtgggtgata tttttgatcg
    68101 aggaactcaa gcagccaaag taatggatcg aatcatggat ttttcctctg tagatatcca
    68161 gtgggggaat catgatattt tgtggattgg tgcgtattgc ggctctgagg catgtttatt
    68221 gacgctttta cggattgccg cacgctacaa ctatttattt gaattagaga aagaatatgg
    68281 attaaattta cgtccattat tttcttttgc ccatcaaacc tatcagaaga atccagtatt
    68341 tacccctaaa aacaggaaag atctatctga aagagagcaa gaagaattag aaaagatcca
    68401 tcaagcactt tctatcctcc aattcaaatc agaacatcag ttgttgaatc gacgacctga
    68461 atttaaaatg gacgatcgta aattgttgga aaaaatcaac tatgaggaat caacgatcgt
    68521 tttagaaggt cagctctatg agttgaaagg gacttgtttt caaacgatcc agccagatga
    68581 tcctaaaaaa ttcttggaag aggaacaaaa agtgatcgat agtttgatgt attcattcca
    68641 gcactcgtta agaatgcaaa aacacatgac gtttttgatc gaaaaagggg gaatgtatct
    68701 cacgaacaat cagcatgtac tgttccatgg ctgtatacct gtagatgaaa aggggcagct
    68761 cttagcattt gaattagacc aatcttatcg cggaaaagaa ctgctgggat tttttgaaaa
    68821 acagataact gaaagcgcaa aagatttgac tgcaaatgaa gatttggcga ccgatttgat
    68881 ttggtatgcg tggagcgggc cattttcgcc tttattcggc aagagtaaaa tggcaacttt
    68941 tgagcgctat tttctcacag agcctcatac gcacgtcgaa aaaagcaatc cctattatca
    69001 cttgcgagat gaagagtggt tcagtgaaaa aattttggca gaattcgatg caaaagaaga
    69061 aggttcagca atcatcaatg gacacacgcc agtaaaagta aaaaaaggag agtcaccgat
    69121 caaagcaaac ggaaaagcat ttgttattga cggaggtcta tccaaagctt atcaaaaaac
    69181 aaccgggatt gctggctact cattactatg caattcttac ggtttccaaa tcgtgacaca
    69241 ttatccgttc ttgcctattg aacaacaatt tgcaaaaaaa tctgatcaaa cgaatgtaaa
    69301 aaaagtgatc gagcagcagc tcccacgcaa acttaatcgg aatacgacaa aaggaatgga
    69361 attacagcaa cagattactc aactccaaag gctgttggat tatcgaaagg acgattgaga
    69421 aaaatgctag ccaacattgc tcaatagact aaaaagcgac tgcaacaaaa ggcgtgtcgc
    69481 agtctccttc ggaattagct caaaaaacgg taaaatatta gaagctattt ttctgtttat
    69541 ttctctaata ctcaggtcag ggcgctgatt tcacgacctc ttccttaaac ggtgttctcc
    69601 tgccaactcc tcggtcacaa gtcacaatat ccaacaaaca tgagaagctg ttttttgaaa
    69661 ttgctccttg tgactcagag ttgaacggca ggctcacgac ctaatcagaa aaacgattaa
    69721 aattcattca caaagaaatc gaataaacgc tgttcagatg aatctacacg atgagaaagt
    69781 tccggatgcc attggacacc aaggattttg tgcatattat ctttactttg gactgcttca
    69841 atgagtccat cgttggaaaa ggcgatggct tttaacaaag gagaaagatc tttgactgcc
    69901 tgatgatgat aggaattcac aaagtatgaa tcagggagaa ggtcacttaa taaactgtcc
    69961 gaaacgattt tgacttcgtg agttgcaaac tgcggggcag tgggctgttg ttcgtgtttt
    70021 acggaccatt ttggatataa tgaaagatct tgataaagtg ttccctccaa cacgacattc
    70081 aatagttgaa gtcctcggca gactgcaaaa atcggttttc tttgtttcaa tgcttccaag
    70141 atcaatgcct gttcgaattg gtctcgttga atatttgttt ccgtcagttt tggatgaggg
    70201 tcttccatgt aaagttgcgg actaacatcc tgaccgcctg caagaatgag tttgtcgatt
    70261 ttctcaatta gttgaggcgc tgaatctgga gacatgactg gcagaataag aggtaatcct
    70321 tgagcatcta aaactgcatc cacaaatccc tgcggtgtat agcttacttg atttccttgg
    70381 aaagtatctg tcgctcgaat cagttgattc ccggcaatgc cgatgattgg tttcattttt
    70441 attcccccta aagtagacta attgtaacaa ggatttaaaa aaatttaaac tatgtaagac
    70501 ttgcccctat acttatctgt tcttgctgtg ttactatctg taaagagaat tttcgtgtga
    70561 aattcatgac gatagttgaa aatattgctt aatttgttat aataaaaagt aagcagaaat
    70621 aaaaaggttg ggcgtaagct tcaaggatct agttcttcaa ggggtgagaa ggacatttta
    70681 ttgaaggggc ctgcctatac taagttatct ttagaggtac atactttcaa tgaaaaaaga
    70741 aagcatgtac ctctttttta aatcgaaagg aagtgaagca agtgttagaa gctttggaac
    70801 aaatccgaaa agcagaagaa gaaaatgaga agcgtgctcg aaccctacgg cagcagttga
    70861 agacctatgc agaagaaaaa gagcaagaat tggagataat ccaaacgaac agtcggcaac
    70921 agctgaaaca gttggtagaa gaaaaagaac aattcgaaaa gcaagaatta gaaaaagaaa
    70981 aaatgaaatt gaaagcagaa gcagacaagg tgcaagcaac tttgaaagac caatatcaaa
    71041 agcatcagag tcaagcaatc ggtgcaatca ttgaaagggt gaaagaaact tatggccgtc
    71101 actaagatgg aaaaagtgac cctcatttca gataaaagaa atcaggagag gattttacaa
    71161 gcagtacaag gaatccaaaa tgttgaaatc cgggatctgt atcaaaatag aacaaacaac
    71221 cagtgggtag aaaaatattt tccagatacc acgattattg ataaagaagc aaaattaagc
    71281 gctttaggca atcggctgaa agacatccaa gaagctatcc aattcataca acaccacggc
    71341 gatagccgtc aaaagaaact ccatttgaaa catcaagaac tttccttaca agacttggaa
    71401 gcaaattatt ccgaagaaaa tttcatgaat aaattagaag aagtccttga tttaaaagaa
    71461 aagtgggaac agctaactga aaaacgtgat cgtttagaag aagaggaaga atggcttctt
    71521 cattggcaac agctggatat tgctccaagt atgtatgcaa gtaagacgac catttttgag
    71581 atggggactg tgagtgcagc aaattttgaa agtttcaagg aagaactaag taagcttgat
    71641 gacgtttata tggaagaaat agattatacg ccaaaacaag tttatctttc gtatgttgct
    71701 ttaaaaaaat cagttgctgc tatagaagaa attgctggga aatacgggtt caataaagaa
    71761 acgtatcctt atgaacaaaa tcctaaagaa aaattgcaag aaaccaaaca gcaattatcc
    71821 attgttcacg agcagcaaaa aaagataacg acagcgttag gtcagtgcag cggctatatc
    71881 caagaatttg aatgggtaga agaagtcaca cttgccgttg cagaacggga aaaagtaaaa
    71941 gaacggttta tccatgccac ttatctgatc gttttgcaag gttgggtaga tgcagaagaa
    72001 aaacagaatt tgatgcatgt gttaaacgaa actgtatcag aagaagatat atacgttagt
    72061 ttcgaaacac caaactcaga agagattcag caggaagtcc ctactaaatt gaaaaaccat
    72121 ccgcttatcg aaccttttga attgctgact gaaatgtaca gtctgccaaa atatgaagaa
    72181 gtagatccaa cgccttggat gacaccattt tatcttgtct tcttcgggat gatggtcgca
    72241 gatgttggtt acggattgct gatgctcatt gggacaatac tagctcaaaa actatttgtt
    72301 ttaccccgcg ggatgaaacg tttcgtaaaa ttctttgaga ttctctcggt accatcgatc
    72361 atctggggat tgatctacag ttcatttttc ggacaggcat taccaaaaga actatttggt
    72421 atccgcttgc ctttcccaat cctatctacg acggatgacg tcaatacgat tttgatttta
    72481 tccgtgattt tcggtctgat acagatcttg gttggattat tcgtggcagc aaaggaaaat
    72541 atcaggagga aagattactt gagtgctgtc agtgatggtt ttgcctggca agggatcctg
    72601 attgggatcg ttattgcatt gattggtgtc atgttgataa aaaatacagc atttgtttat
    72661 cttggcgcgg ggctatcgat cattgctgct ttatgtatct taatcgtgcc gattatccaa
    72721 tcgccgtcta aagtcaaggg tgctgccaaa ggagcgtata atctttacgg attgactggt
    72781 tatatcggtg atttagtcag ttatacacgt ttgatggcac taggtatttc aggcggaagt
    72841 attggcgcgg cattcaatat gctagttgct ttcatgccgc cagccgctcg attcagtgta
    72901 gggatccttt tgatcatcgc tttacacgca ctgaatatgt ttttgacact gttaagtgcc
    72961 tatgtccatg gtgcacgatt gcagtatgtc gaattttttg gaaaatttta tacaggaggc
    73021 ggacgtgcct ttgacccgct gaaaacggcg gaaaaatacg tcaacatcaa tcataagaaa
    73081 aaaaacaata aataattgga ggatttttat acaatgatgg attacttaat tagtcaaaat
    73141 ggtggaatgg tatttgcagt attagcgatg gcaacagcga cgattttttc agggattggt
    73201 tcagctaaag gtgttggaat gacaggtgag gcagcagcag cgttaacaac aagtcaaccc
    73261 gaaaaattcg gacaggcttt gattctgcaa ttgcttccag gtacgcaagg gttgtatgga
    73321 ttcgttatcg cctttttgat ttttatcaac ttaggaaatg atatgtcagt tgtacaagga
    73381 ttgaactttc taggcgcttc tctgccgatt gcttttacag gtttgttttc aggtatcgcc
    73441 caagggaaag ttgcagcagc aggtatccaa attttagcga aaaaacctga acatgctaca
    73501 aaaggaatca tttttgctgc gatggttgaa acatatgcga ttttaggttt cgttatttcc
    73561 ttcctattag tattgaatgc ctaagcataa aggaggaaaa gcagatgaac gccattgaaa
    73621 aaatcatctc tcagatgaat gaagcagcag agcaagaaag agcggcgtta gagcaagaag
    73681 agcgaatgaa gatcgatcaa aactttgaac aaaaacgtac gcaaatcgaa acagaacatc
    73741 aaaaacaaaa agaaaaacaa atcgaattac ttgaaaaaaa ataccgtcag cttaggaatc
    73801 gccaacaagt agaagtacga caagaaaatt tgaatgcgaa gcaggaattt ttacgacgat
    73861 tgtttgcaga tgcaatagct gaaatggaga attgggatga atctgaacaa atccagttta
    73921 tcaaaaattc attgtattca ttacctttga caggcaaagt aacattcatt gctggagaaa
    73981 aatcagcagc ttatctttct cagacattgc tggatgaatg gaacaatgaa cttcccttta
    74041 tgatggtttt aagtgatgaa actgttgctg atcaagcggg ttttctgata aacgatcaag
    74101 gagttcagta taattttctt ttcagcagcc ttgtacaaga tatccaagga acgatgagtt
    74161 ttgagattgc caatcaatta ttcgaataag gagggatcag tgtatggaat accacgaact
    74221 aaatcccttg attcgcggaa gagagcttga acttttgtcc aatgagacat ttgaacggat
    74281 gattcaaaca aattctgtcg aagcacttgg tgaaatattg aaatccacga tttacagtcc
    74341 atatatttat gacggatatg aatatgactt cgaacagaat cttttaaagg agcagagccg
    74401 tctatttcgc tggttaaagg aatcagcacc ggagcctgaa atcgtttgga tctatacgat
    74461 gcgctatact ttccataatc tgaaggtttt gacaaaagcc gagatgacaa atcaaaatct
    74521 ggaccatttg tatatcgacg atggatttta ttcattagaa accttgaagg atgccattca
    74581 tacgcaagtt tcaaatgaac tccctgaaag cattatggac agtatacgag aagtacgtga
    74641 ttattttgaa gagtctacca ttcttcaggg aattgacgtg atttatgatc gacagttttt
    74701 gacagagcag cgacggcttg ccgataagct aggatatcaa gaattgctga cagaagtcat
    74761 tgcttttatt gacttgacca atatcacaac gatggctcga ggaatattgc agaaaagaac
    74821 atatgggttc atgacgacgg tactttccag ctcgggaagt atcgaaaaag aagtattttt
    74881 gaactttgta gataaagata tggaagatta cacgaatttt ctattagaga cagattatgc
    74941 tgattttctg cgccctgtca tccgtgaggg aaatcttgat ctcgtaaagc ttgaacagtt
    75001 gaaagatgat tatctaagtt cattgtatca agaagcacaa acccaggctt tcggaccact
    75061 gccactacta gcctttttga acgcaaaaga ggtagaaagc aaaaaccttc gtttactggt
    75121 tatcggcaaa agaagccatt tcgaaccaga aacaatcaga aagcgggtga gacaagtcta
    75181 tgacgcataa gatcggtgta gttggcgaca aagattctgt tttgccattc aaattgtttg
    75241 gctttgatgt tcgttatggt acaaccaagc aaaccgttcg tcaggcaatt gaagaaatgg
    75301 caaagaatga gtatggcgtg atttatgtca cagagcaatg tgcagcattg agcccagaaa
    75361 cgatcgaacg ttacaaggaa caaatgatac ctgctatcgt attgattccc aatcatcaag
    75421 gatcattagg gatagggctg gaagaaattc aaaaaaacgt agaaaaagca gtaggtcaaa
    75481 atatcttata gtatgaaaag gagatagaaa ttttgcaaat tggaaaaatc ataaaagtct
    75541 ccggacctct tgtaatggct gagaacatgt ctgatgccag tatccaagac atgtgtctag
    75601 tgggagatct aggagttatc ggagaaatta tcgagatgcg tggcgatgtg gcgtctattc
    75661 aagtatatga agagacttct ggaattggtc caggcgaacc ggttcgctct actggtgaag
    75721 ctttatctgt tgaattagga ccagggatca tttcacaaat gtttgacgga atccaacggc
    75781 cattagatac ctttatggaa atcacacaaa gtaatttctt agggcgcgga gttcaattgc
    75841 ccgcattgga ccatgagaaa aaatggtggt tcgaaccaac agtagaagcc ggagaaacgg
    75901 tgagtgctgg agatgttatc gggatcgtag aagaaacaaa agttataaaa cataaaatca
    75961 tggtgccaaa tgggataaaa ggaacgatca aaacaatcga aaaaggttca ttcactattg
    76021 atgaaacagt atgtgtcatt gaaaccgaaa atggtgacaa aaatttgacg atgcttcaaa
    76081 aatggccagt aagacgtagt cggccaatca aagaaaaatt aaacccggat gcacccatga
    76141 tcactggaca gcgagtgatt gatacattct tcccagtgac aaaaggagga gcagcagctg
    76201 tacctggtcc ttttggtgca gggaaaacag tcgttcagca tcaaattgca aaatgggccg
    76261 atgtggacat ggttgtctat gtgggatgtg gcgagcgtgg aaatgagatg acggatgttt
    76321 taaatgaatt ccctgaattg attgacccta atacaggaga atcgttgatg gaacgtacgg
    76381 tattgattgc taatacatca aacatgccag tagcagctcg agaagcttct atctatacgg
    76441 gaatcacaat tgcggaatat ttccgtgaca tgggttatga cgttgctatc atggcagact
    76501 ccacttcacg atgggcagaa gcacttcgtg agatgagcgg acgtttggaa gaaatgcctg
    76561 gtgatgaagg ttatccagct tatcttggtt cacggcttgc ggaatactat gaacgatctg
    76621 gaagagtcat tgcattagga tcagaaggtc gcgaaggaag tataaccgca atcagtgctg
    76681 tatccccgtc tggaggggat atttcggaac cagtcacaca aaatacattg cgggtcgtaa
    76741 aagtattctg gggtcttgat tccagtttag cccaaaaaag acattttcct tcgatcgatt
    76801 ggatacaaag ctattctctt tattcaacag aagtagggaa gtatatggat catatccttc
    76861 aagctgactg ggcatccatg gtcaccgagg gcatgcgtat tttgcaggaa gaacagcagc
    76921 tgaatgaaat cgtgcgtttg gtagggattg attccctttc agataatgac cgtctgacat
    76981 tagaagtggc aaaatccatt cgtgaagatt atttgcagca aaatgctttt gatgatgtcg
    77041 atacattcac ttcaagagag aaacaattca aaatgttgaa gatgatcttg acctttggtg
    77101 aagaaggacg ccgtgcgttg tcgttaggtg cttatttaag tgagatcatg gacggtaccg
    77161 tatcgattcg tgaaaggatc ggacgaagca aatatatccc ggaaacagaa ttagaaaaac
    77221 tagatcaaat tattggtgaa atcaagcaaa cgatgcaaac gatcgtttca gaaggaggca
    77281 tgagcaatga ttaaagaata tcgtacgatc ggtgaagtcg tcggtccatt gatggcggtt
    77341 gaaaaagttg ctggtgtcaa atatgaagaa ttaatcgaag tccgtatgca aaatggcgag
    77401 attcgtcgtg gacaagtatt ggaagtccaa gaagataaag caatggtcca aatattcgaa
    77461 ggaacaagtg gtatcaattt acgtgactct tctgtacgat ttttaggcca tcctttagaa
    77521 ctaggtgtat cggaagacat gatcggtcga gtattcgatg gtttgggacg accgaaagat
    77581 aacggaccag agatcctgcc tgaaaagcat ttggatatta acggagaagt aatcaatcca
    77641 gtagctcggg attatccaga tgagtttatc caaacaggta tctctgcaat cgatcatttg
    77701 aatacattag ttcgtgggca aaaattacca gtattttctg gctctggtct tcctcataaa
    77761 gaattagctg ctcagatcgc gcgacaagca acggtactcg attcatcaga tgatttcgcc
    77821 gtagtctttg ctgctattgg aatcactttt gaagaagctg aatttttcat ggaagatttt
    77881 cgtcaaacgg gcgcaatcga ccgttctgtc atgtttatga atttagcaaa cgaccctgca
    77941 atcgaacgta tcgctactcc tcgtatggct ttgactgctg cagaatatct tgcttatgaa
    78001 aagggaatgc atgttttggt tatcatgaca gacatgacca actatgcaga ggcattgcga
    78061 gagatttctg cagcacggcg agaagttcca ggaagaagag gatatcctgg gtatctttac
    78121 acgaacttag ctactttatt cgaacgagca ggaagaatcc gcggactaaa aggatcggtt
    78181 actcaaattc cgattctaac aatgccagaa gacgataaaa ctcatccaat ccctgacttg
    78241 actggttata ttacagaagg acagatcatc ttgactagag agctttacaa gagtgggatt
    78301 cagccaccaa ttgatgtact cccgtctctt tcgcggttaa aagataaggg aactggaccc
    78361 ggaaagacaa gagaagacca tgcagctacg atgaatcagc tttttgcagc ctatgcacaa
    78421 ggaaaacagg caaaagaatt agccgtagtt ttaggtgaat ctgctttatc tgatgtagac
    78481 aagatctatg cgaagtttgc tgagcggttt gaaaaagaat atgtcaatca aggattctac
    78541 acgaaccgtt cgattactga aacacttgat ctagggtggg aactgctatc gatgttgcca
    78601 agaaccgaat taaaacgaat caaagacgac atgctggaca aatatctgcc agaagggaag
    78661 tgagttctga tggcacgatt gaatgtgaat ccgacccgca tggaattgac tcgattgaaa
    78721 aaacagttga caactgccac aagagggcat aaattattaa aagataagca agatgaactg
    78781 atgcgtcaat tcatcctgtt gattcgaaag aacaaccagc tgcgtcaaga aatggaagag
    78841 tctatgacag aagcaatgtc tgattttgta ttggcaaatg cttcgatcac ggaacctttc
    78901 atcgaagaat tatttgtttt gccggcggaa aacgttgatt tgtctatcgt agacaaaaat
    78961 atcatgagtg taaaagtacc tgtgatgaat tttgaatatg atgaacagct gacagacaca
    79021 cctttggaat acgggtattt gaattccagt gccgaactgg atcggtcaat cgatcggttt
    79081 actaccctgc ttccaaaact tttggaactg acagaaatcg aaaaaacttg tcaactgatg
    79141 gcgagtgaaa tcgaaaagac acgtcggcga gtcaatgcat tagaatatat gacgatccct
    79201 caattagaag aaacgatcta ttatattcgt atgaagctgg aagaaaacga gcgcgcagaa
    79261 gtaacaaggt tgatcaaagt aaaaaatatg ggtaccactg actaagtggt atcttttttt
    79321 aaaagaggaa aacgatgatt aaacaaagca aacaaataaa gaaacgtttg ccggctgttc
    79381 agcttctcgc attaggattt tttctcctga ttttagttgg cggcggccta cttaccctac
    79441 cattttttag taatagtggg catgggacaa attttatcga tgcgcttttc actgcaactt
    79501 ctgctgtctg tgtaacggga ttgacaacat tgaatacagc agagcattgg aacagtgctg
    79561 gtcaattttt gatcatgctt ttgattgaga tcggcggtct tggttttatg atggttccga
    79621 ttctatgctt tgcattgata aagaagaaag tcagtctcag cacacgtatt atattaaaag
    79681 aagcgctgaa tctagaagaa gtatcaggtg tgatgaagct catgctttac atcctaaaat
    79741 tggcctttgt tatccaattg attggtacgg ttgctttatc ttttgtattt gtgcctgaat
    79801 ttggctggtt gaaaggtatc tggtacagtt tgttccatgc aatctctagt ttttgtaatg
    79861 cagggtttga tttgttagga gacagtttag ccaatcacca gcaaaatgtt tatttgatca
    79921 tggtggtatc tgctttgatc atttctggtg ggttaggctt catcgtatgg cgtgatttac
    79981 tggaatatca tcagaaaaag aagatgacga ttcattcaaa aatcgcatta accgttacag
    80041 gtaccctttt attaggcgga ttcgttgtgt tctttttcac agagcgcaat ggggcaacgc
    80101 tagtggaagg gaatatgttt caacgattgg caaacacctt ttttatgagt gtgacaccta
    80161 gaacggctgg atattattca gttgattacc tccatatgag ccatgcaggt ctgattttaa
    80221 cgatgttttt gatgtacatc ggcggaacat ctgggtcgac ggccggcgga ttgaaaacaa
    80281 ctacgttagg tgtgttgctg atccagatgc gttcgatgtt gaaaggacgt acgagagcgg
    80341 aagcatttgg ccgtaccatc cgacaaggcg cagtgttgcg ggcacttact ttattttttg
    80401 ttacgttgac gttgtgtgta gtcgccatca tgattttatc ggtgactgaa acgataccta
    80461 aaacttctgg catcgaatat attgcttttg aggtcttctc tgcgtttggt acagtaggtc
    80521 ttacgatggg attgacgcca gacttgactg caatagggaa attgatcatt atagcgctta
    80581 tgtacattgg acgagttggt gtattgactg tggtcttctc tctgatgaca aaagcacaaa
    80641 gaacacaatc aaaatacaaa tatccagaag aaagtgtcat gattggataa tttcatcttc
    80701 tgacagaaac ctagtgattt agtaaaataa gaaaataaaa taatttttct tgcttcttgg
    80761 atactttaag tgcaaaatgt tcgtttattt tttgaggcac tacccgttgt tgaacctcgg
    80821 gtagtgcctc ttttttattg aaaggaatca ataagatttg attcctttat ttatcaatag
    80881 gttataattc atattttttt attttttctt ttacgatact tagtccagaa gctaaaattt
    80941 caaggttatt agaggatagg gaaattcgaa cgaatgcatc tggttgcgca cgtgtagtaa
    81001 agcgtctgga atgataaagt cggataccgt tagcaagaaa gtcattctca attatcttag
    81061 ggtcaatctc aggatcaact ggaagaattc gatagtaagg gacacgattc gttggttttt
    81121 ctactttgaa aagagaatca aaaagctgat tggctctttt tgtaagactt aatttagttt
    81181 ctaagatcct atttgcttca tttgaatgga ggatttgagt gatgacttcc acatctaatc
    81241 cagaagtttt cacatttata ttaaaaattg cttgttctat cttgctttgg acatgtactg
    81301 gaactacaag ataagcaact cgcaatccag aacaaataaa ttttgtcatt ccagctaagt
    81361 agattgtttg gttaggtaat aaattttgga aaggaggaat gatcgtatgt tgatagtaag
    81421 ttgttaaaaa tgaatggata tcatcttcaa taacccatag accttctttt tcaatcactt
    81481 cggctaattg ctctcgtctt ttgtgagaga tttgaaaccc tataggatta ttacaagaag
    81541 gcataagaaa gacaccatga atcttctttt ttctacattc ctgaatcaat atatcaggtc
    81601 gcattccttg ctcgtcaaaa tcaattggaa cgatctctaa atgatataac tgagccaatt
    81661 caatgaaatt agcgtatgta tatcggtctg ttgctattct atcacctgga gagaaaagtg
    81721 cagaaagtgt gatagccaat ccattttgaa caccggaaac aatagataga gattctaagg
    81781 acggaatgac tccttgagtt tttaaccaat ttgctgcagt agtcaattga aaatttgtgc
    81841 ctttgggatc ttggtaatta agcaaaccaa caagatttgg gttattacta gttgattgaa
    81901 taaacgggac aacgaattta ttacattctt caaaagaact aaccagacca aaatcaatga
    81961 tatgttcggt tacttcattg gtagagatgg tgatggactc aaagacattg ggagaaataa
    82021 atgtgccact tccaatattc gtatacagca aacctttctc aattccatat ttataagcct
    82081 tgccaacggt agtaaaattt aaatctaaat aatcagctag ctctctttgg gagggtaact
    82141 gagtgttttt ctgtaattta ttctttaaaa tatcttgttc taattgttga atcaacgatc
    82201 gataataagg acgcttcaat ttttgtttgt ctggtcgcca agttaacggg taattgtcat
    82261 aagaattaat aggcattttc tccactcctt aaaattgtat accatacaat tttaccattg
    82321 attgtattga ttttagaagt taatcttttg tgaggaggga attgtctatg aaaattatta
    82381 attttgagga agtagtagct tcttttagtt ttgaagaagc gattcaagta atgaaaaaat
    82441 gtttttttga ttatgaaagt ggtaaaatca gccaaaatcc tcgattggtg gaaattttac
    82501 ctgacggaaa aggcaaaaat atgtttgcga tgatgcctgc ttatttgggg gagaacagat
    82561 attttggcac aaaagtcatt accgcttttc cggataatca tcagtatcat ttaccttctc
    82621 atttaggaga gattttcttg tttgatgctc aaaacggact acccaaagca ttgataaacg
    82681 caaatgcagt cacctggatt cgaacagctg ctgtatctgc gctggcaaca gattacttag
    82741 caaatccgca tgcagaaaca cttgctttaa ttggagctgg tcaacaagca ttgtcgcatt
    82801 tgactgcgat ttctaccatt cgtcccatca ctacagtgtt tgtttacgat attttagaag
    82861 aaagacgaaa tacttttatc gctaaagcta aaaaacagta tcctaaaata acgtttataa
    82921 atgcaatatc agtagaagat gcagtacgtc cagcggaaat catttgtacg ttgacctcta
    82981 gtaaagaggc atttcttcaa aaagagtggg taagggaaga cgcacatatc aatgctgtgg
    83041 gcacatttac tcctgataca agagagataa gtacatcgtt gatggaaact tctcaaatct
    83101 atgtagatga ttactcagct gccttaacag aaagcgggga cctgcttata gccatggcag
    83161 aaggagattt agaggaatct tgtattgttg gtacattagg cgaattagtt tctgagaaaa
    83221 aaacatttta taaaggagaa tcgaggccga cgattttcga cgcagttggt ctagctattg
    83281 aagatctttg ttgtgcagaa tatatttata acaaattaga gaaaggggct ttaaaatgaa
    83341 cttagattat tacgtagttg atgcatttgc agatgaggtg ttcaaaggaa atccagcagc
    83401 ggtttatgtg ctagaagaat ggctgccaga aggtacgatg caaaaaattg ccattgaaaa
    83461 caatttatct gaaacagcat ttacagtgaa gaaaaaccaa gaatttgagc ttagatggtt
    83521 tacgccagat cgagaaatcg atctttgtgg tcacgcgaca ttagcaacag catttgtttt
    83581 atttaactat tacaaaatac ctgatgaaac gattaaattt tctactcaaa gcggtaatct
    83641 atttgtgaca agaattaaag attattatta catggatttt cctagtatta tgccgaaaaa
    83701 agtgccgata ttgtctgaat atgaagaagc gattggggct aagattaaag aagcctactt
    83761 agcacgtgat ttatttttcg tattagaaga tgaaaaaacg gtggctaaat tgcagccaga
    83821 ttttacagct atcaaaaatt ttgaattagg aataggagtc atcgtgacag cagaaagtgt
    83881 gcaaaaagac tttgtttcta gaaccttctt tccaaaatta acaatcaatg aagatccagt
    83941 atgtggatca gcacattcta atcttattcc ttattgggca gaaagaatga ataaaacaaa
    84001 attgtcagct tatcaaatgt catcaagggg cggggatcta gaatgtgaat taaaagaaga
    84061 tcgtgtgata ataggaggaa aagcagtttt gttttctaaa ggtacctcgt ttatttgatt
    84121 tctttcaaat gaattaaaaa taaattggtg gagagtggca accttatagc tacaatggtt
    84181 gttaaaaaaa gacgcaaact ttttcaattt aatgaaaagt ttgcgtctca ttttaattat
    84241 tggtgtttgt tttttattca atcaagagta aaatgcccca tactaactat cctcggatga
    84301 cttcgatttt ataaccatca gggtcaatga caaagtagta agaaggcgca gtgccaggta
    84361 atccttttaa gtcagtaatc tcaagaccgg cagctttatg ttgctcgtgt aatttttcta
    84421 gatcatcagc tgctatagcg atatgaccat agccgtctcc tagatcatac gcaccatgat
    84481 catagttgta agtcaactct aattcatagt catccccagg aagtgtcaaa taaacaagtg
    84541 taaatttgtt ttctggaaaa tcacggcggc ggctttcttc aaaaccaaat gccttttgat
    84601 aaaattcgat tgatgcttca agatctttca ctcgaacaca tgtgtgagcc attttcatag
    84661 attcatctct ccttttcctt ttactcaatc ataacaaaaa gaagtaagga aatagttgat
    84721 ttgtgcttgt tcatgagaaa tttctcatgt aaaatggata gaaaataaaa ctgttaaggt
    84781 ggaaactatt catggataaa ccaatttttg gtgaaaaaaa gcaatttgct gattatcaaa
    84841 cccgttatgc agcatatatt gtcatagaaa gagatcagca gattgcagta atcgaggctc
    84901 caaatggtgc tttttttctt cctggcgggg aaattgaagg agaagagacg aaagaagaag
    84961 cgattgtccg tgagctgata gaagaaatgg gaattgtggc agaaatttct tcttatctgg
    85021 gagaagctga tgagtatttt tactcgaatt atcgtgcaac ttattattat aatccaggat
    85081 atttctttgt tgctgattct tggaagcgta taggagaacc aactgaaaag accaataaaa
    85141 tttggtgggt gagccctcaa gaagcgcttg tgaaattgaa acgtggtagc caccgatggg
    85201 cagtcgagag atggatcgaa aaaaataaaa actgaaagaa agcgagtaga tcagctttct
    85261 ctcagttttt ttatttatta cagtacatat tttttgattg cttcagctac accgtgctcg
    85321 tcgtttgatg aagtgatgac atttgctgct tctttgacaa gagaaacggc atttcccatt
    85381 gctactccta gaccagcata ttcaatcatg gataagtcgt tctcgttatc tccgatagcc
    85441 atgatttcat cttgatcaat accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta
    85501 cttgcttctt tatttagtac ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta
    85561 tcacggaaag tttgcggtaa acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc
    85621 atcatcattt tgacgatgtt catgtctggt gtcatttctt caggtgttcg atattttagc
    85681 ggcatcttga ctaaacttgc ttcgtggatc gtataagcgc tgatatctcg attaggcgtg
    85741 tagatcgctt tgtcatcgat cgaatggaga tgactgccga cacggcgtgc catcacttcg
    85801 atctctagga aatcttcatg tgtcagtccg tgacgggcga tgattttacc tgatttcgtt
    85861 tgttgtacga gtgccccgtt ataagtaata acgtaatcat tatcttgaaa aaggttcaac
    85921 tcgtttaact gttcctggac acctggtaag ggacggccag tgcataaaac gatcgaaaca
    85981 ccttttgcaa cagcagcggc aatcgcttct tttacttctt ttgttacttc tcttttctca
    86041 tttaataaag taccatcgat gtcgatagcg actagtttga tagacataat ttcctccaat
    86101 atattttaat ttatttcaat caatgcgcca ttacggatat ggctggcaaa ttcttgataa
    86161 gtttcgtcaa ataaatcata atgatcacgc aaggacggat caaccatttc ttttggaaag
    86221 aaaaatcgct catctccttg ttcttgtccc gctaatgcag caacaagctg actaacctgt
    86281 gataattcta tcaaagttcc gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct
    86341 tgttctgggc gataaaaatc ataaggtaga tcgtagctag aattcacagc agtgtaataa
    86401 acaggattat atccgacctt ttctactaac aaagtgagtt cttggactaa ttttgaatcc
    86461 cggttgccag aaaaagtagc agatttcagt ggtttacgat tcaaaaaacg tttagctaaa
    86521 tcatttaaaa taggatcagc agattcagac cattgagtaa agtaagtgcc caagacccca
    86581 tcatcaagtt tgaggtattc ttctaaagta aagcttccgt caagaaatgg cagaagtaat
    86641 tgagaatgga gttcaaaact gctggcatct tcttgataca actcgtgtgc gcgatgaagc
    86701 agatgctcca aaattacttc cataccacgg gaaacaggat ggaagtacac ttgcacatac
    86761 atttgatatc ggctaacgat ataatcttcc actgcatgca tgccactcat ggaaaaagcg
    86821 atcccgcctt cataaggacg aatcacacgt aatattcggg taagatcaaa tgttccatat
    86881 tctgttccag tgaaataagc atcccgaagc aaatagtcca ttcgatctgc atcgatctga
    86941 ctagaaatca tttggacaac ttgtgggttg gggtaagttt tttggatcac actagctacc
    87001 ttttcaggaa aaccttcttc tactcggtta agaatctgat acacttctgt ttctggagaa
    87061 gtgatgatct ctacagtgat ggcttcatga ttcgtatgga agatatgttc aaatgtatga
    87121 gagtaaggac catgaccgac atcatgcaac agtgccgcac ataaagtcac cagccgttcc
    87181 tgatcatccc agcctccgtt gcctattttt tcttttgaaa aatttcgaga aaagatatcg
    87241 cagattcgtc ttgaaatctc ataaacgcct aatgaatgag taaaacggct atgttctgct
    87301 ccgtgaaaag tgaaagaaga agtgcctaat tgtttaatgc gtcgtagacg ttggacttct
    87361 ttcgaattga tcaaatctaa gattacttga tgctggacat ggatatagtt atggactgga
    87421 tcacgaaaaa ctttttccat aggcagcatt tgatatttat aaggggttgt cataatgtag
    87481 ctcctttatg ttattacgtt gttccattct ctggatttgg ttgttccatt gctccagctg
    87541 gatttctttt tttagccagt cggtagaatc ctgtaaatca cttgcagaat acagcttttc
    87601 aaaagctttt gcaaatgctt ctttgacttc ttttacaaaa aggggttggt caagcagttc
    87661 ttcaagtgtt gccattgtag caggatccac tgcaggatag ccatttgtac caaagtcttc
    87721 ttttaaagca gattgataaa atcgcttcat gacttgcccg cgtttttcct gattaccgtt
    87781 gacacttaag tacatcataa cagaaatccc atttttgatc cgacgctgag cgataccggc
    87841 aaattttttg ccatggatgc ttaaatcata agttccagga caataagaat gggtgatttc
    87901 gaatgcttgt atcggtgcct ttggaaaagc gtatttagtc aataggagca tttgctcgta
    87961 agcgtcatct atggttattt tttttgtgtc actttggggg aaaatcaaag aaatattcaa
    88021 aattccttca tctgatacga tccctaatcc acctgaattt ctgatcactg gagcgtaacc
    88081 tgcatctttc agtgtttgga tcccgtcact tagaaaagga gttcgaacat ccttcatacc
    88141 taagatgact gtgcagtcat attgccagaa atgtaaaaag atttgctggt gttctttaga
    88201 atattccgtt aatatatctg ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg
    88261 ctgatctagt cgaatcgcag ggttcattca accggctcct ttgtataaat tcatattttc
    88321 tacaatatta tactctaaaa tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg
    88381 gacaagttgg ttgacaaaac aaaagaaact aggaacaatg tagctatgag aagtaaagga
    88441 gaatgaataa tggaattatc acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta
    88501 aaacagcaag gggaagtgca agatttttat tttgatttga aagggcaaat ggtgacaatt
    88561 ggcgatacgc tgtacatacg ttataaagag attcaggagg agacgggcga tgagattcct
    88621 gtaacgatca aattagttcc agatggtcat gtacagctga tccgtgcagg agaaatgcgg
    88681 atgcgtttga aatttggcta taaagaacgg ttagaaacat cctatcgaac accatacggt
    88741 atgatccaga ttgctacttt tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca
    88801 ggagggaagg ttcgaatcga ttatgatctg ttcatgggac cggaaaaaat cggcgaatat
    88861 tatttgacct tggattttac agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga
    88921 ttttgtatga taaggagtag actgtgaaag gacgtgtcct gattggaaat tagtgtattt
    88981 gaaggtgcaa acaaaagcga attatcaatg atcgaagtag cacacgcgat cttagaacaa
    89041 cgtggcgatg tcatggattt ttctgattta gctaaccaga tccaaaacta tcttgggaaa
    89101 tcagacagtg aaattcgtga ttcactcgca caattttata ctgacttgaa tattgacggc
    89161 agctttatct cattagggga taatcgttgg ggcttgcgtt catggtatgc tatcgattcg
    89221 atcgatgaag aagtaaacca tggaatggac gaagaggatg aagatactcc acgtcgccgt
    89281 aaacgcaaga aagtcaacgc ctttatcaat gatgatgaag acgcgatcga ttacaatgac
    89341 gatgacccag aagatacaga tctgacagaa gaagatgacg atgatctgtt tgatgacgat
    89401 gatgatgaag atgaagaaat cgctgcttat aattctgact tgcaagaaat cggagcagat
    89461 gacccgacag atgatgaaga agacttgcca ggaaatatcg aagaagattt aagtatcata
    89521 gacgaagacg atgatgatga agattatgaa gaggaagaat tttctgactc tgaaaaagaa
    89581 taaacattat tttcttacga gaggttgtga cagagacgat cagcctatca gaataaggag
    89641 gtgtgacacg atttttgtca caccttcttt tttgtatata aaaatcccaa gtaaatacat
    89701 aaaaaataaa aaaattgaaa cttttagcgc accttgtacg tcatattaag tgaggcagaa
    89761 aggagtggag aatgattttt actggatata agaaaaaacg gcagatcgaa aaataccgtc
    89821 acctgctgaa tggactcatc gaaactgatt atcaaaaaat gttccgtatc acgatgaatt
    89881 acgtacatga taaagaagag gccttagatg tgatgcaaga tagttttcat aaagccctga
    89941 actattttga aaaagaaaaa gagatcgagc attttagtgc atggttttat cggatattga
    90001 tccgcacggc attagatagt tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa
    90061 ttcaagatat cccccaacag ttacctttag aaacttccgt tgcagagctc catatgattt
    90121 tagataaaat agacagtccg gaaaaagaga ttctgatcct ctactttttt gaaggatttc
    90181 gtttgaaaga aattgcgact atcttggata tgaatgaaaa cacagttaaa acgaaaatgt
    90241 accgctcatt gaatgcttta cgtcaaatcc tagaatgaag gagagaagag tgccatgtat
    90301 tcccaaaaag aaaatttaaa aaaactaaag aaaacttata aagaacaagc aattcccaaa
    90361 gggcttaaag aggagatccg ccagcgtttt attatcgaag agcaatcatt tataaaagca
    90421 aagcggagaa agagacgtct ccaagggttc ggagtatctt tggctatcgt aatgattaca
    90481 acaagtagcc ttctttttaa tagtcaagtt cgaagctttg cagaagattt acccatctta
    90541 ggatcagtca ttgaattgat cttaggcgaa cgctttactg atcgatctga aaaaatcgat
    90601 attcaggtac cgaagatcaa tacacaaaat gagaaagaaa ataaaacaat tcatggatta
    90661 aatcaaaaat actttcgcga aggacaagca gattttgaaa aagctgaaaa agaatatgga
    90721 aattttgaaa cggatcatta ccaagttttg ggagattatc agaaaatcgt agacgataac
    90781 cggtttctcg tgattgaaag gcagatcacc caaacagcag cagatagcca tgttgaaaaa
    90841 agatacgaca caatcgacaa gaaaaacagt gtccagctct cacttccact tttattcaaa
    90901 gatgacacct atctatctgt tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc
    90961 aaggaagatc catctaagta ctattggact gagcaagata ttcaagaagg gacgatagaa
    91021 aaaccaacac ttgttacgcc tacacgaagt ttttatttga acaaagagca tcaattagtt
    91081 ttgacttttt ctcaatacga aattgctcct ggttatatgg gtacaccaga atttgtcatt
    91141 cctaagtccg tgacaaaaac gattttggca tcggaagatt atttggatca ttagacgaga
    91201 agtagttgcg actagcagtt tcaattttca agtaagtaca agtaaataat aagaagagaa
    91261 aaagagaaag aagagatata gtgaaaagaa attatttagt tatcagtatt attgctttat
    91321 ccgtgctttt gtttttcgaa attacttcgg tggcctcctt gatcaccgaa gtaaaaggac
    91381 aaacacactc ttcggagcat tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta
    91441 aaagccaatc aactgaaaca gctaacgtca aagaagccat tcaagaatca gcggaaaagg
    91501 tacaaagtca gtcatcacaa tcaacacaag acagtacaaa aacgagccga gatccggctg
    91561 tcaaaagcgt cgcaatcagc tttgatgatg gaccaggagc gaccacaaca ccgcagcttc
    91621 tgcgaatctt aaaagaaaaa aacgtgcatg ccactttttt cgtcttagga gaaaatacgg
    91681 cgcagcatcc tgaaatcgtg aagcagacag ctgaagcagg gcacgagatt ggcaatcaca
    91741 catacgatca tcagaatctg gccactcttt ctgcccagtc gatgacggag gaagtgacga
    91801 aagcagacac tgagatcaaa aaagtcactg gcaaaacccc cacttttgtt cgtccgccct
    91861 atggttctgt cacgaatgta ggagcaacga tcatccagcg accgatcatc gaatggtctg
    91921 ttgattcaga agattggaag acaagaaatc ctgatttgat tttgcagaag atccaagcaa
    91981 cagtatacga tggggcaatt attttattcc atgatatcta tcctgaaacg attcgtgccg
    92041 ttcctcaagt gatcgattat ctgaaagagc aagggtatcg catcacgaca gttggggatt
    92101 tattagggca tccaacggct gtcgagaact attatggcag aaacgatcat cggccagttc
    92161 agtaagtgag acaagtatct ttaataaata acacatttta ataagtagtt gaacacataa
    92221 ctaccttact tgcaaaggct taacaatatc tatacaggta caacaaaaaa ctgtccacca
    92281 attttctttg gcggacagtt ttcacttaaa aataaagaag caactattcg taaattatgc
    92341 taaaatagca gtagaacgcg tcctgaggga atcgaacccc cgtctcaaga accggaatct
    92401 tacgtgatat ccactacact aaggacgcaa gcactgggat aattgtaact aaacagataa
    92461 aaaattacaa ggggattgga caaaaaaatg aaatttgagc aaaatttttc acaaaaacag
    92521 cagcagacac agaaactagc catgacgcaa cagttgcaac agtccatcca agttttacaa
    92581 tataacagtg aggagctgtt ggcattcgtt gagaatcaag caatggaaaa tccattggtg
    92641 gaagttgttg agccggaatg gcagccagat tacataaaag cttcttcatc ttcttatgaa
    92701 ggagaagaga caaattacct aaatcagatt cctgatacaa aagggtcttt atttgattca
    92761 ttgatcgaac aagtccattt gaattaccga gatacttttt tgaggaaaat cgttctttat
    92821 cttgtagaat acatcgattt gaacggattt ttgacgatta gtttagaaga agccggaaaa
    92881 gagattggag ctacgcctat ccaaatgctc gatgcgttga ctctgattca gcaattagaa
    92941 ccagctggag taggtgcacg tagtttgcaa gaatgtctca tgcttcaaac agaacgagat
    93001 gattatgcgc cggaattagc ttatatcgtg ttggaagaat gttttgagga actggtggag
    93061 cgaaaatgga aagaaatcgc acaacgtttt tctgttgatc tacatgctgt tcagcagata
    93121 ttcgactatt tacaaacgtt gagtccaagc cctggccgga ttttcgaccg tagcagcgaa
    93181 ttgtacatta ttcctgatgt ccgggtatta gtggacgacg ataaaaatgt acaagttatc
    93241 tcaaaccgaa aaaatcagcc aaatatacgc tttcaagaga gttacttcaa acaaatgtca
    93301 caacaagcag ataaagaaac tgaaaattat ttaaaagaac ggaaacagga attcgaatgg
    93361 ttgaagaaaa cgatcctaca acgtggggat acaattttgc gggttgctca agtcattgtt
    93421 tcccggcaaa aagctttctt tatcgacaag gaacgtccaa tcaagcctct tacgttaaag
    93481 gaagttgcaa ctgagataga tgtgcatgaa tccacggtca gtcgtgcagt caacgggaaa
    93541 tatttggaaa cagacttcgg tgtatttgaa ttaaaaaaat ttttcactac acgaattcct
    93601 acgaatagta cagaacagac agaagacctt tcagcagata cagcgaagaa aaagctgcag
    93661 gaattagtcg atcaagaaga caaaaacaag ccgttgtctg accagaaatt ggttgaattg
    93721 ctgaaaaaag atgagatagc gatctcaaga cgaacagtag caaaatatcg tgatttatta
    93781 ggaatcccga gttcatcaaa aagaaaacgt tatgataact aatcagtcaa aagactagaa
    93841 aaagtatttc actttttcta gtctttttag ttgaaaaacg agagcaaaac tgttagactt
    93901 acagtcgtga ggttgagatt tccctttatt gatgtgaaat tcgaatagtt aatttctttt
    93961 tttatcgtat atgggtcgtt ttaagtctac attggacgta aagtgtccaa ctaaggagat
    94021 cgctatgctg gatgaaataa aaatgattga atctgttgca ccagatatta tcgaagtgtt
    94081 gcaagaacgc tataaaattt tacgaaatat ctattggatg cagccgattg gacgtcgaag
    94141 tttatcggaa agtatgggga tcacagaacg agtattgcga acagaaacag atcttttgaa
    94201 aaatctgaat ttgatcgaca cctcaaaaag cggtatgacg ctgacaacta agggcgaaga
    94261 agtttatcaa agccttgaaa acttcatgga tcagctttta ggtacgcatc aaaccgaaca
    94321 acagttggca gaatattttg gtaaccaacg ctgtatcgtt gtttcaggaa acagcgaaga
    94381 gcagaccaaa gtggctgatg cattcggcga agcgctgagc gaagccctag accgactact
    94441 tccagaaggc gagaatatca tcgctgtgat gggaggaact actatggctg tggtagccga
    94501 acaattgtct aatctggaaa ataagaaacg gcataacctg tttgtccctg caagaggcgg
    94561 gattggtgaa gcgataactg tacaggcaaa ttctgtcagt gcaagaatgg ctgctaaagc
    94621 aaacggtaac caccgtgcac tttatgttcc ggaacaatta agtctggcaa cttacaattc
    94681 tttactcaat gagccatcta tccaagaagt cttaaacttg attagtgaag cgaattgtgt
    94741 tattcatagt attgggcgtg cattacacat ggcagcacgt cgtaagatga ctgaaaaaga
    94801 attagtcatg ctgaaacaag caaatgctgt tgcggaatct tttggctact ttttcaatga
    94861 aaaaggtgaa gtcgtttata aggtccctag aatcggcata gaattgcaag atttggaaaa
    94921 agtcccgatc atcatggcaa tcgcgggcgg aaaatcaaaa gccaaagcaa ttcgagctta
    94981 tatgaaaaat gcaccaaaac aaacgtggct catcactgat gaagctgctg caaatgagat
    95041 tttaaaaggg gtaacccttt aaaataaata tttttttgat tttcataagg aggaaatctt
    95101 aaatgacagt taaagtaggt attaatggtt ttggacgtat tggacgtcta gcattccgtc
    95161 gtatccaaga tgtagatgga atcgaagtag tagcaatcaa cgacttgaca gatgctaaaa
    95221 tgttggcaca cttgttaaaa tacgacacaa ctcaaggacg tttcaacgga acagttgaag
    95281 ttcatgaagg ttcattcaac gtaaacggaa aagaagttaa agtattagct aaccgcaacc
    95341 cagaagaatt accatggggc gaactaggcg tagatatcgt tctagaatgt actggtttct
    95401 tcacttctaa atcagcagct gaaaaacatt taacagctgg tgctaaacgc gttgttatct
    95461 ctgctcctgg cggaaacgat gttccaacaa tcgtttataa cacaaaccac gaaacattaa
    95521 ctggtaaaga aacagttatc tcaggtgctt catgtactac taactgttta gctcctatgg
    95581 ctaaaacatt gaacgacaaa tttggtgttg ttgaaggatt aatgacaact atccacgctt
    95641 acacaggtga ccaaatgact ctagacggac ctcatcctaa aggtgacttc cgccgtgcac
    95701 gcgctgctgc tgcaaacatc gttcctaact caacaggtgc tgctaaagct atcggtttag
    95761 taattcctga attgaacggt aaattagacg gagctgctca acgtgttcct gtaccaacag
    95821 gttcattaac agaattagta acagttcttg aaaaagaagt aactgttgac gaaatcaatg
    95881 cagcaatgaa agaagcttca aacgaatctt acggatacaa cacagacgaa atcgtttctt
    95941 cagatatcgt tggtatgact tacggttcat tatttgatgc tacacaaact aaagtaatga
    96001 cagttggcga caaacaatta gttaaaactg ttgcttggta cgacaacgaa atgtcataca
    96061 ctgcacaatt agtacgtact ttagaatact tcgctaactt ataagataga caaacgtaca
    96121 agtgtaaatt atagacatgt acatttaaaa gcggggaagc aatcgcgctt cttccgcttt
    96181 ttttgataat aagtttattc aggaggaaat aaaatggcta agaaaacagt gaaagatatc
    96241 gatttaaaag acaaaaaagt tcttgtccgt gttgacttca acgttccttt gaaagacggc
    96301 gtgatcactg acgacactcg tatcaaagca gcattgccaa caatcaacta cgttctagaa
    96361 caaggcggaa aagcaatcct tttctctcac cttggacgtg taaaaacaga agaagataaa
    96421 gaaggaaaat ctttagctcc agttgcaaaa cgtctaggcg aattattagg taaagaagta
    96481 acattcgtac ctgaaactcg cggagaacaa ttagaagaag caatccgcaa catgaatgac
    96541 ggcgacgttg tcgtattcga aaatacacga tttgaagata ttgacggtaa aaaagaaagc
    96601 aaaaatgata cagaactagg taaatactgg gcttcattag gcgatgtatt tgttaacgat
    96661 gctttcggta cagctcaccg tgcacatgct tctaacgtag gtatcgcttc aactggtatc
    96721 ccaacagttg ctggattctt gatggaaaaa gaaatcaagt tcatcggtga agcagtagaa
    96781 gaaccaaaac gaccaatgat tgcaatcctt ggtggcgcaa aagtttctga taaaatcggc
    96841 gtaatcgaaa acttgattcc taaagcagat aaaatcttga tcggtggcgg aatgacttac
    96901 acattctacg aagcaaaagg aatcaagatc ggtaactctc tagtagaagc tgataaagtg
    96961 gaactagcaa aagaattaat cgaaaaagca ggcgacaaac ttgtcttgcc aatcgacaat
    97021 gtctgtgcac cagaattttc aaatgatgtt gaaacacaag taatcgaagg agacattcct
    97081 gatggtttga tggctttaga catcggccca gcatcagtaa aattatttgc tgatacatta
    97141 caaggtgcaa aaacagttgt ttggaacgga cctatgggtg tatttgaaat gagtaacttt
    97201 gctaaaggta caatcggtgt ttgtgaagca atcgctaact tagaaggcgc aacaacaatc
    97261 atcggtggcg gagactcagc cgcagcagca gaacaattag gatttgctga caaattcaca
    97321 cacatctcaa caggtggcgg cgcaagcttg gaattgcttg aaggtaaaga attaccagga
    97381 ctagcagcaa tcaacgataa ataaacgacc aagtttgctc aattctgacg agtaatcgat
    97441 caaaaggtga agggagtttt catgactccc tagccatttt tcaataaatt aaggagtgtg
    97501 ttcctcaatg cgtaaaccta ttatcgcagg taactggaaa atgaacaaaa ctgcatcaga
    97561 agcaaaagaa tttgctgaag cagtaaaaaa caaaatccct tcaaatgaca aagttgattc
    97621 agtcatcgga tctcctgcat tattcttaca agaattaatg acatcagctg aaggtacaga
    97681 actaaaaatc tcagcacaaa actgctactg ggaaaactca ggtgcgttca ctggtgaaac
    97741 ttcaccagca gctcttgctg atctaggtgt tcattatgtg atcatcggac attcagaacg
    97801 tcgtgaatat ttccatgaaa cagacgaaga catcaataaa aaagcgaaag ctatctttgc
    97861 aaatggtatg acaccaatcc tatgctgtgg cgaatcttta gaaacctatg aagcaggcaa
    97921 aactgctgaa tggatcgaag gacaaattac agctggttta gctgatcttt cagctgaaca
    97981 agtgtcaaac atggttattg cttatgaacc aatctgggca atcggtactg gtaaatcagc
    98041 tgacgcacaa atcgctgacg aaatttgtgg agttgtacgt caaacagttg aaaaacttta
    98101 tggaaaagaa gtatcagaag cagttcgtat ccaatacggc ggttctgtaa aaccagaaaa
    98161 tattgctgaa tacatggcaa aagaaaatgt tgacggtgct ttagtcggtg gcgcaagctt
    98221 gcaagcagat tcattcttgt cattgttaga cgctgtaaaa taattgttga aaatttgcga
    98281 aaaatgcaag aaatgtttgc actaatgagc aaaattaact aaaatcgtat atgagggaaa
    98341 tcccttagga aaaaacaaac tcaaaggaga gacaaaacat gtcaattatt actgatgttt
    98401 acgctcgcga gatcttagac tcacgtggta acccaacaat cgaagtagaa gtatacacag
    98461 aaagcggagc ttttggccgc ggaatggttc cttcaggtgc ttcaactggt gaatacgaag
    98521 cagttgaatt acgtgacgga gacaaagctc gttatggcgg taaaggtgta actaaagctg
    98581 tcgacaacgt aaacaacatc attgctgaag caatcattgg ctacgatgtt cgtgaccaaa
    98641 tggctatcga caaagctatg atcgctttag acggaactcc taacaaaggt aaattaggtg
    98701 cgaacgctat tttaggtgtt tctatcgctg ttgcacgtgc agctgctgac tacctagaag
    98761 tacctttata ccactaccta ggcggattca acacaaaagt attgccaaca ccaatgatga
    98821 acatcatcaa cggcggatca catgctgata actcaatcga cttccaagaa ttcatgatca
    98881 tgcctgttgg cgctccaaca ttcaaagaag ctctacgtat gggtgctgaa gtattccacg
    98941 cattagcttc aatcttgaaa gctcgcggat tagcaacttc tgttggtgac gaaggtggat
    99001 ttgctccaaa ccttggttca aacgaagaag gttttgaagt aatcatcgaa gcaatcgaaa
    99061 aagctggcta tgtacctggt aaagacgttg ttcttgctat ggatgctgct tcttcagaat
    99121 tctacgacaa agaaaaaggt gtttacgtac tagctgattc aggcgaaggc gaaaaaacaa
    99181 ctgacgaaat gatcaaattc tacgaagaat tagtttctaa atatccaatc atctcaatcg
    99241 aagacggatt agacgaaaac gactgggacg gattcaagaa attaactgac gtattaggcg
    99301 acaaagttca attagttggt gacgacttgt tcgtaacaaa cactcaaaaa ttatctgaag
    99361 gtatcgaaaa aggaattgct aactcaatcc ttatcaaagt gaaccaaatc ggtacattaa
    99421 cagaaacttt cgaagctatc gaaatggcta aagaagctgg ctacacagca gttgtatctc
    99481 accgttctgg tgaaacagaa gattcaacaa tctctgatat cgctgttgca acaaacgctg
    99541 gccaaatcaa aactggttct ctatcacgta ctgaccgtat tgctaaatac aaccaattac
    99601 tacgtatcga agaccaactt ggtgaagttg cagaatacaa aggtttgaaa tctttctaca
    99661 acttaaaaaa caaataattc ttttctaatg aagatacatg atcgactatt gaaagatagt
    99721 cgagtatgat cacttagtta agtaatcgaa ctctctactt gctgaaatat cagcaggtag
    99781 agagtttttt
//
LOCUS       DAFEML010000004        94572 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFEML010000004
VERSION     DAFEML010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 94572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.004"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            476..1339
                     /locus_tag="LP468_000322"
     CDS             476..1339
                     /locus_tag="LP468_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2079887.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="LP468_000323"
     CDS             complement(1468..3090)
                     /locus_tag="LP468_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2079888.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="LP468_000324"
     CDS             3339..3860
                     /locus_tag="LP468_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2079889.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP468_000325"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP468_000325"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL2079890.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="LP468_000326"
     CDS             5941..6759
                     /locus_tag="LP468_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL2079891.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="LP468_000327"
     CDS             complement(6862..7059)
                     /locus_tag="LP468_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079892.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="LP468_000328"
     CDS             7228..7806
                     /locus_tag="LP468_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2079893.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="LP468_000329"
     CDS             7901..8038
                     /locus_tag="LP468_000329"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079894.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="LP468_000330"
     CDS             complement(8851..9354)
                     /locus_tag="LP468_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2079895.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="LP468_000331"
     CDS             9713..10738
                     /locus_tag="LP468_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2079896.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="LP468_000332"
     CDS             11061..11939
                     /locus_tag="LP468_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL2079897.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="LP468_000333"
     CDS             12415..12531
                     /locus_tag="LP468_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2079898.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13460..13798
                     /locus_tag="LP468_000334"
     CDS             13460..13798
                     /locus_tag="LP468_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079899.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13892..14122
                     /locus_tag="LP468_000335"
     CDS             13892..14122
                     /locus_tag="LP468_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079900.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14522..14893
                     /locus_tag="LP468_000336"
     CDS             14522..14893
                     /locus_tag="LP468_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL2079901.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15167..15859)
                     /locus_tag="LP468_000337"
     CDS             complement(15167..15859)
                     /locus_tag="LP468_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2079902.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15862..16647)
                     /locus_tag="LP468_000338"
     CDS             complement(15862..16647)
                     /locus_tag="LP468_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2079903.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16884..18284
                     /gene="lacG"
                     /locus_tag="LP468_000339"
     CDS             16884..18284
                     /gene="lacG"
                     /locus_tag="LP468_000339"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL2079904.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18309..18626
                     /locus_tag="LP468_000340"
     CDS             18309..18626
                     /locus_tag="LP468_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2079905.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18639..20312
                     /locus_tag="LP468_000341"
     CDS             18639..20312
                     /locus_tag="LP468_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL2079906.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20326..21957
                     /locus_tag="LP468_000342"
     CDS             20326..21957
                     /locus_tag="LP468_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL2079907.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22448..24013)
                     /gene="guaA"
                     /locus_tag="LP468_000343"
     CDS             complement(22448..24013)
                     /gene="guaA"
                     /locus_tag="LP468_000343"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL2079908.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24072..24995)
                     /locus_tag="LP468_000344"
     CDS             complement(24072..24995)
                     /locus_tag="LP468_000344"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL2079909.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25191..25796
                     /locus_tag="LP468_000345"
     CDS             25191..25796
                     /locus_tag="LP468_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2079910.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26104..27120
                     /locus_tag="LP468_000346"
     CDS             26104..27120
                     /locus_tag="LP468_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2079911.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27261..28562
                     /locus_tag="LP468_000347"
     CDS             27261..28562
                     /locus_tag="LP468_000347"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL2079912.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28608..29270
                     /gene="deoC"
                     /locus_tag="LP468_000348"
     CDS             28608..29270
                     /gene="deoC"
                     /locus_tag="LP468_000348"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL2079913.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29291..29689
                     /locus_tag="LP468_000349"
     CDS             29291..29689
                     /locus_tag="LP468_000349"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL2079914.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29755..30837
                     /locus_tag="LP468_000350"
     CDS             29755..30837
                     /locus_tag="LP468_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2079915.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31049..32611
                     /locus_tag="LP468_000351"
     CDS             31049..32611
                     /locus_tag="LP468_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079916.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32604..33737
                     /locus_tag="LP468_000352"
     CDS             32604..33737
                     /locus_tag="LP468_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079917.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33737..34693
                     /locus_tag="LP468_000353"
     CDS             33737..34693
                     /locus_tag="LP468_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079918.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34792..35958
                     /gene="deoB"
                     /locus_tag="LP468_000354"
     CDS             34792..35958
                     /gene="deoB"
                     /locus_tag="LP468_000354"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL2079919.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35982..36800
                     /locus_tag="LP468_000355"
     CDS             35982..36800
                     /locus_tag="LP468_000355"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2079920.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36817..37524
                     /gene="deoD"
                     /locus_tag="LP468_000356"
     CDS             36817..37524
                     /gene="deoD"
                     /locus_tag="LP468_000356"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2079921.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37822..38508)
                     /gene="gpmA"
                     /locus_tag="LP468_000357"
     CDS             complement(37822..38508)
                     /gene="gpmA"
                     /locus_tag="LP468_000357"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2079922.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38680..39261)
                     /locus_tag="LP468_000358"
     CDS             complement(38680..39261)
                     /locus_tag="LP468_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2079923.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39394..40077)
                     /gene="rpiA"
                     /locus_tag="LP468_000359"
     CDS             complement(39394..40077)
                     /gene="rpiA"
                     /locus_tag="LP468_000359"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL2079924.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40396..40809
                     /gene="rpsL"
                     /locus_tag="LP468_000360"
     CDS             40396..40809
                     /gene="rpsL"
                     /locus_tag="LP468_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL2079925.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40893..41363
                     /gene="rpsG"
                     /locus_tag="LP468_000361"
     CDS             40893..41363
                     /gene="rpsG"
                     /locus_tag="LP468_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL2079926.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41457..43544
                     /gene="fusA"
                     /locus_tag="LP468_000362"
     CDS             41457..43544
                     /gene="fusA"
                     /locus_tag="LP468_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL2079927.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43716..44903
                     /gene="tuf"
                     /locus_tag="LP468_000363"
     CDS             43716..44903
                     /gene="tuf"
                     /locus_tag="LP468_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2079928.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45310..45618
                     /gene="rpsJ"
                     /locus_tag="LP468_000364"
     CDS             45310..45618
                     /gene="rpsJ"
                     /locus_tag="LP468_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL2079929.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45649..46278
                     /gene="rplC"
                     /locus_tag="LP468_000365"
     CDS             45649..46278
                     /gene="rplC"
                     /locus_tag="LP468_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL2079930.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46306..46929
                     /gene="rplD"
                     /locus_tag="LP468_000366"
     CDS             46306..46929
                     /gene="rplD"
                     /locus_tag="LP468_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL2079931.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46929..47219
                     /gene="rplW"
                     /locus_tag="LP468_000367"
     CDS             46929..47219
                     /gene="rplW"
                     /locus_tag="LP468_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL2079932.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47258..48091
                     /gene="rplB"
                     /locus_tag="LP468_000368"
     CDS             47258..48091
                     /gene="rplB"
                     /locus_tag="LP468_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL2079933.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48134..48412
                     /gene="rpsS"
                     /locus_tag="LP468_000369"
     CDS             48134..48412
                     /gene="rpsS"
                     /locus_tag="LP468_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL2079934.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48435..48782
                     /gene="rplV"
                     /locus_tag="LP468_000370"
     CDS             48435..48782
                     /gene="rplV"
                     /locus_tag="LP468_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL2079935.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48796..49452
                     /gene="rpsC"
                     /locus_tag="LP468_000371"
     CDS             48796..49452
                     /gene="rpsC"
                     /locus_tag="LP468_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL2079936.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49455..49889
                     /gene="rplP"
                     /locus_tag="LP468_000372"
     CDS             49455..49889
                     /gene="rplP"
                     /locus_tag="LP468_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL2079937.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49879..50067
                     /gene="rpmC"
                     /locus_tag="LP468_000373"
     CDS             49879..50067
                     /gene="rpmC"
                     /locus_tag="LP468_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL2079938.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50092..50358
                     /gene="rpsQ"
                     /locus_tag="LP468_000374"
     CDS             50092..50358
                     /gene="rpsQ"
                     /locus_tag="LP468_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL2079939.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50416..50784
                     /gene="rplN"
                     /locus_tag="LP468_000375"
     CDS             50416..50784
                     /gene="rplN"
                     /locus_tag="LP468_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL2079940.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50821..51129
                     /gene="rplX"
                     /locus_tag="LP468_000376"
     CDS             50821..51129
                     /gene="rplX"
                     /locus_tag="LP468_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL2079941.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51157..51696
                     /gene="rplE"
                     /locus_tag="LP468_000377"
     CDS             51157..51696
                     /gene="rplE"
                     /locus_tag="LP468_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL2079942.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51715..51900
                     /locus_tag="LP468_000378"
     CDS             51715..51900
                     /locus_tag="LP468_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL2079943.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51936..52334
                     /gene="rpsH"
                     /locus_tag="LP468_000379"
     CDS             51936..52334
                     /gene="rpsH"
                     /locus_tag="LP468_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL2079944.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52366..52902
                     /gene="rplF"
                     /locus_tag="LP468_000380"
     CDS             52366..52902
                     /gene="rplF"
                     /locus_tag="LP468_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL2079945.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53063..53419
                     /gene="rplR"
                     /locus_tag="LP468_000381"
     CDS             53063..53419
                     /gene="rplR"
                     /locus_tag="LP468_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL2079946.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53440..53940
                     /gene="rpsE"
                     /locus_tag="LP468_000382"
     CDS             53440..53940
                     /gene="rpsE"
                     /locus_tag="LP468_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL2079947.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53955..54134
                     /gene="rpmD"
                     /locus_tag="LP468_000383"
     CDS             53955..54134
                     /gene="rpmD"
                     /locus_tag="LP468_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL2079948.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54178..54618
                     /gene="rplO"
                     /locus_tag="LP468_000384"
     CDS             54178..54618
                     /gene="rplO"
                     /locus_tag="LP468_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL2079949.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54618..55913
                     /gene="secY"
                     /locus_tag="LP468_000385"
     CDS             54618..55913
                     /gene="secY"
                     /locus_tag="LP468_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL2079950.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55975..56622
                     /locus_tag="LP468_000386"
     CDS             55975..56622
                     /locus_tag="LP468_000386"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL2079951.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56813..57031
                     /gene="infA"
                     /locus_tag="LP468_000387"
     CDS             56813..57031
                     /gene="infA"
                     /locus_tag="LP468_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL2079952.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57064..57180
                     /gene="rpmJ"
                     /locus_tag="LP468_000388"
     CDS             57064..57180
                     /gene="rpmJ"
                     /locus_tag="LP468_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL2079953.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57198..57563
                     /gene="rpsM"
                     /locus_tag="LP468_000389"
     CDS             57198..57563
                     /gene="rpsM"
                     /locus_tag="LP468_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL2079954.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57591..57980
                     /gene="rpsK"
                     /locus_tag="LP468_000390"
     CDS             57591..57980
                     /gene="rpsK"
                     /locus_tag="LP468_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL2079955.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58060..58998
                     /locus_tag="LP468_000391"
     CDS             58060..58998
                     /locus_tag="LP468_000391"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL2079956.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59026..59406
                     /gene="rplQ"
                     /locus_tag="LP468_000392"
     CDS             59026..59406
                     /gene="rplQ"
                     /locus_tag="LP468_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL2079957.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59678..60517
                     /locus_tag="LP468_000393"
     CDS             59678..60517
                     /locus_tag="LP468_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2079958.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60493..61362
                     /locus_tag="LP468_000394"
     CDS             60493..61362
                     /locus_tag="LP468_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2079959.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61352..62149
                     /locus_tag="LP468_000395"
     CDS             61352..62149
                     /locus_tag="LP468_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2079960.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62352..63098
                     /gene="truA"
                     /locus_tag="LP468_000396"
     CDS             62352..63098
                     /gene="truA"
                     /locus_tag="LP468_000396"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2079961.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(63553..66222)
                     /locus_tag="LP468_000397"
     CDS             complement(63553..66222)
                     /locus_tag="LP468_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL2079962.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(66460..66648)
                     /locus_tag="LP468_000398"
     CDS             complement(66460..66648)
                     /locus_tag="LP468_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL2079963.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            66918..67280
                     /locus_tag="LP468_000399"
     CDS             66918..67280
                     /locus_tag="LP468_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2079964.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            67332..69014
                     /locus_tag="LP468_000400"
     CDS             67332..69014
                     /locus_tag="LP468_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL2079965.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            69131..71167
                     /gene="recG"
                     /locus_tag="LP468_000401"
     CDS             69131..71167
                     /gene="recG"
                     /locus_tag="LP468_000401"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL2079966.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            71216..72217
                     /gene="plsX"
                     /locus_tag="LP468_000402"
     CDS             71216..72217
                     /gene="plsX"
                     /locus_tag="LP468_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL2079967.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            72339..72581
                     /gene="acpP"
                     /locus_tag="LP468_000403"
     CDS             72339..72581
                     /gene="acpP"
                     /locus_tag="LP468_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2079968.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            72849..73853
                     /locus_tag="LP468_000404"
     CDS             72849..73853
                     /locus_tag="LP468_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079969.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            73854..74798
                     /locus_tag="LP468_000405"
     CDS             73854..74798
                     /locus_tag="LP468_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2079970.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            74798..75760
                     /locus_tag="LP468_000406"
     CDS             74798..75760
                     /locus_tag="LP468_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079971.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            75787..76701
                     /locus_tag="LP468_000407"
     CDS             75787..76701
                     /locus_tag="LP468_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2079972.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            76727..78508
                     /locus_tag="LP468_000408"
     CDS             76727..78508
                     /locus_tag="LP468_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2079973.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            78856..79542
                     /locus_tag="LP468_000409"
     CDS             78856..79542
                     /locus_tag="LP468_000409"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL2079974.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            79562..83143
                     /gene="smc"
                     /locus_tag="LP468_000410"
     CDS             79562..83143
                     /gene="smc"
                     /locus_tag="LP468_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL2079975.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            83152..83961
                     /locus_tag="LP468_000411"
     CDS             83152..83961
                     /locus_tag="LP468_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2079976.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            83972..84970
                     /gene="ftsY"
                     /locus_tag="LP468_000412"
     CDS             83972..84970
                     /gene="ftsY"
                     /locus_tag="LP468_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL2079977.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            85157..87424
                     /gene="gshAB"
                     /locus_tag="LP468_000413"
     CDS             85157..87424
                     /gene="gshAB"
                     /locus_tag="LP468_000413"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL2079978.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(87513..87965)
                     /locus_tag="LP468_000414"
     CDS             complement(87513..87965)
                     /locus_tag="LP468_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL2079979.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            88115..89065
                     /locus_tag="LP468_000415"
     CDS             88115..89065
                     /locus_tag="LP468_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2079980.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            89058..90017
                     /locus_tag="LP468_000416"
     CDS             89058..90017
                     /locus_tag="LP468_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2079981.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            90014..90769
                     /locus_tag="LP468_000417"
     CDS             90014..90769
                     /locus_tag="LP468_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2079982.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            90792..91745
                     /locus_tag="LP468_000418"
     CDS             90792..91745
                     /locus_tag="LP468_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2079983.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(92389..92685)
                     /locus_tag="LP468_000419"
     CDS             complement(92389..92685)
                     /locus_tag="LP468_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL2079984.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            93040..93396
                     /locus_tag="LP468_000420"
     CDS             93040..93396
                     /locus_tag="LP468_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2079985.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            93406..94305
                     /locus_tag="LP468_000421"
     CDS             93406..94305
                     /locus_tag="LP468_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL2079986.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        30401 a        16886 c        20147 g        27138 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgttttattt tccctctgtt
    13441 tagccaagta acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt
    13501 tcgtgctaca gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc
    13561 tagtgagcca attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt
    13621 tatggtggta aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat
    13681 tgaaaaggtg agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat
    13741 cattttaacg gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac
    13801 actagtgaaa tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa
    13861 atcgatcatc aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat
    13921 ttattacgtg aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag
    13981 tcgctactca attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa
    14041 aactgttttt tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga
    14101 ttatgttagt atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg
    14161 ttattgtttt ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt
    14221 atccagagta ttttatttta acttttgtat atttagtaag tagctacaca cttctatata
    14281 aattcagaag ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat
    14341 aatatttttg atttatatag gaaattaaaa atattataga atcaacactc agagaacggg
    14401 ttggttttta atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga
    14461 agttggttac cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat
    14521 aatgagagat tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa
    14581 tgaattatct gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga
    14641 ctatattgat atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat
    14701 aaaagctttt atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct
    14761 agtaggaaaa ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc
    14821 tttgtctatg ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt
    14881 ggaaatcttt taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga
    14941 tgatttttaa gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag
    15001 atagagatga acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat
    15061 ttcactaagg atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag
    15121 gaggtgtgca tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg
    15181 atgtggcaga caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat
    15241 ttagctgtgc ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg
    15301 ttccgatccc cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac
    15361 aatcagccgg agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt
    15421 tcccagggaa agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat
    15481 cgaaaatatc aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg
    15541 gaatctgttg gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct
    15601 cgttttcatt ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg
    15661 cgatctcaga ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc
    15721 gaccatgaat attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta
    15781 tcatatgcag ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat
    15841 caaatataat ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat
    15901 ttgcagatcg acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt
    15961 aatgagcaga tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt
    16021 tttattatca acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc
    16081 tccttcttcg gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa
    16141 tgcttttgta aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc
    16201 ggtatttttc cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag
    16261 aatatcaaaa actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt
    16321 cgccaatagt tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa
    16381 ggaggctgct gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt
    16441 gtgagaaagt tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag
    16501 cagcttgccc gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc
    16561 taattgattg atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat
    16621 agtaagcaat ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca
    16681 tataaacgga caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat
    16741 gtttgttaca atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt
    16801 tgttgacaaa tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat
    16861 tatagatttg aggagagatg tacatgctta aattaccaga agattttatt tttggcggag
    16921 ccacagcagc ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt
    16981 gggatgactt tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc
    17041 atcaatatgc aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat
    17101 ccattgcttg gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg
    17161 ctttttatca tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt
    17221 tgcatcattt tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa
    17281 caatagaagc atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg
    17341 tgtggagtac ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt
    17401 tcccaccagg aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg
    17461 ttgctcatgc ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg
    17521 tagttcactc attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg
    17581 cctttttaga cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt
    17641 attcaactga aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc
    17701 attttcctga agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag
    17761 ggatcaatca ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc
    17821 ataacggtac gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta
    17881 tttataaaga aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat
    17941 atgacttgtt gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg
    18001 agaacgggat ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa
    18061 tcgactattt gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg
    18121 tgaaggggta ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca
    18181 aaaggtatgg cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag
    18241 cttactggta caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg
    18301 aagaaaagat gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag
    18361 gcgacgctcg cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac
    18421 atgttgattc ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa
    18481 caaaaatttt agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc
    18541 atgggcagga tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg
    18601 tactgtacag acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa
    18661 tcgaaaaagg gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc
    18721 gtgacggatt tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg
    18781 ctgcggttcc tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga
    18841 aagtctataa ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct
    18901 gcttggctga ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg
    18961 tgatgctggc ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat
    19021 tttcaacgga atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa
    19081 cagttaattt atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag
    19141 ttcctggaac gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg
    19201 cggccgtttt aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa
    19261 tcattacggt gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta
    19321 tctggggagc gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc
    19381 cggcaattgc ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg
    19441 gtgaacaagc ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag
    19501 gaactggggc aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt
    19561 tgaaggcagt tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc
    19621 tatttgcggc acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg
    19681 ttgtaaacgt ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt
    19741 acgttttgcc ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta
    19801 tcttagcttt tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat
    19861 tttgcaaagc atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg
    19921 caaccgagga aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag
    19981 ttatcagcga tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa
    20041 gtgcgatgtt agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg
    20101 caatggcggg tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct
    20161 tagcaccgca agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa
    20221 tcaagctggt tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag
    20281 ctgttcagtt tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt
    20341 tggttgcgta aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa
    20401 actgttgaag catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat
    20461 atggaaaaat ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt
    20521 ttaaaaaata atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt
    20581 aatggagaaa gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa
    20641 cgagcaaaaa atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt
    20701 gatcctggga aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat
    20761 acggcattgt acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat
    20821 cctgatatgg ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag
    20881 tcttggggag aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc
    20941 caagctgttc gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt
    21001 ggcgatacag gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt
    21061 gatttaattg gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc
    21121 aatatgaatg cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat
    21181 gggcatacaa cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct
    21241 gcggggggat atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat
    21301 cggattcagg cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg
    21361 tacaacggaa atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc
    21421 actatgggaa acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca
    21481 agcttgcgtg cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc
    21541 gaaagcgatg gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc
    21601 gctaagggta cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt
    21661 tggcaggatc aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga
    21721 acttacacat tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat
    21781 atcaaaaatt atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca
    21841 aaaattacaa tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc
    21901 aaggcttcag gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact
    21961 gcggatcgtt tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc
    22021 aggaatcgaa cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt
    22081 ttaccaaaac gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt
    22141 caacgatttc gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt
    22201 tgtttaagaa agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga
    22261 tagaaaaaag ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg
    22321 aaacaaatta acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa
    22381 atcaagcatt ttagctattg aagaatgttg atttataggg attccccctc catattatgt
    22441 tggctcttta ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac
    22501 ggttgacgtg ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg
    22561 ggatacgggc aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg
    22621 tgtagtcgta agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag
    22681 tgaaatattg ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag
    22741 catcagattc gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac
    22801 caagaccagg accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag
    22861 tccctaattc acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt
    22921 gcatatcttc tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg
    22981 taccagattc gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt
    23041 caccagcaag ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt
    23101 tacgtttttg ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat
    23161 tgactttgat gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt
    23221 cgcctttgcg tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt
    23281 tttgtaaaag aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt
    23341 ttttgtcacc aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg
    23401 tccagttacc ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt
    23461 attcggaatg acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt
    23521 ggatagaagc aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt
    23581 tagttaccaa gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca
    23641 agacagcttg atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag
    23701 gctctacgga accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata
    23761 caggaatacc taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac
    23821 tgtttggtcc gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag
    23881 taatgcggtg gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca
    23941 attggttata ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg
    24001 caacgtttgt caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact
    24061 attttaaaat gctaatattt tcgcatgaaa atcgaatcga tgatgtgatt ttcagtttta
    24121 tggagaatta tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa
    24181 ttcacatttt tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca
    24241 aaacgataat aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga
    24301 tccaaatacc atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa
    24361 aagtcgctga cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg
    24421 atcaagatat caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca
    24481 tgtgagtaaa caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg
    24541 atcagcatct ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct
    24601 tttaatatac gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt
    24661 ttgaaggtac gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct
    24721 acacttccgg cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa
    24781 cctttactca agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga
    24841 ggtacataga tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta
    24901 tctagttcat cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct
    24961 cttgccacac ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca
    25021 atggaactat tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc
    25081 tttttgtata atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat
    25141 acataaaagg atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc
    25201 attactattc tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa
    25261 aaggcagaac ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt
    25321 atggttcacg tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga
    25381 tcttagatgt gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc
    25441 ggtttgttga aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa
    25501 agcgtaacca aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg
    25561 aagaaaccta tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac
    25621 atgaaatttt gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga
    25681 tccagaagaa acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg
    25741 cagaaatcgt cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag
    25801 ctgaaaaata gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca
    25861 gttctttttt tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat
    25921 agtaggaaca gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga
    25981 aggctgccaa gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct
    26041 ctattctttt cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat
    26101 aggatgaagc tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc
    26161 tcacagattt tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg
    26221 tcgatcgtga atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga
    26281 cattcaaaga ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg
    26341 atcgaaggtg tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct
    26401 cgtcatagcc aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac
    26461 ggaatcttgc tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt
    26521 tatcaaaaaa tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg
    26581 cttatcgtaa aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc
    26641 catacgaaga tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc
    26701 aacggatatc gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa
    26761 catggagagt tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa
    26821 gatatcacgg ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc
    26881 gatgaattgg gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag
    26941 ctgtcagaat acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga
    27001 ttttatgctg cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac
    27061 aaagtgttcg aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa
    27121 ctcggcggta tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt
    27181 tagtaaacca gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg
    27241 aagacaagga ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa
    27301 acgagctgtc gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc
    27361 cagattatca agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag
    27421 aaatcacgaa cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc
    27481 ttgaaggaat aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga
    27541 ttttagcccc cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc
    27601 taggttacac aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc
    27661 tttcggatga agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat
    27721 caggaaactt ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg
    27781 ttgattctct tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag
    27841 atgcaatcgt tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg
    27901 caagacgtct ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg
    27961 cggttatctc agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg
    28021 tcgaggcaat cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg
    28081 ccttaggaag ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa
    28141 cgttgcttca agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc
    28201 aaaatcaagg gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct
    28261 acacaatgga gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat
    28321 taggaattgc tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc
    28381 acgctgttgg attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac
    28441 tattgacgat ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa
    28501 atattgaaat tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat
    28561 aaaggaaaaa agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc
    28621 gaatgatcga ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta
    28681 tcgaagaagc aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc
    28741 tagcgaaaga acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc
    28801 taggagcaaa cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg
    28861 cagatgaagt cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag
    28921 tccaaaaaga tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta
    28981 ttattgaaac atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag
    29041 ctgcaggcgc tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag
    29101 aggatgtccg tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg
    29161 gtatccataa cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa
    29221 caagcgcagg agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa
    29281 ggagaagctc atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga
    29341 taaagcctat gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg
    29401 caagatttat caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga
    29461 gcgcacagct tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt
    29521 agcggggcac acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga
    29581 attctgttcc cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac
    29641 gaccgttcgt gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat
    29701 tcagtcagct gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa
    29761 aaagcaaaat tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca
    29821 tgcggcaaca acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact
    29881 gcagcattga tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg
    29941 gaaggactag aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa
    30001 tatttccaat cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct
    30061 ggattcaaaa cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca
    30121 acaaacaata caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac
    30181 gttgtatctg caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct
    30241 tatacgactg aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat
    30301 cgttttgatg ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa
    30361 atcaaagtat tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt
    30421 gctcaaggta tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt
    30481 aacggtgtat tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt
    30541 atcggtgttg accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa
    30601 aacttcacat tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa
    30661 aaatcagcgg acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac
    30721 ggtgttggtc taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca
    30781 aaagaaaaaa tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac
    30841 catttctata gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa
    30901 ttgttcattt atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta
    30961 atgtttgttt caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag
    31021 atagaaatcg ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca
    31081 gaatattacc aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa
    31141 ggcaggagaa attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa
    31201 cgtgctttcc ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt
    31261 aaagatcaca agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt
    31321 tatgcttgtt gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg
    31381 cgcagggatg cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta
    31441 tggattgtca gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg
    31501 ggtagaaatt ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac
    31561 agctgtattg acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa
    31621 agaaggcaag tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga
    31681 ccgctgtaca gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac
    31741 ctcacaacaa ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa
    31801 agaagcgaag cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg
    31861 tggattagaa gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat
    31921 cgctggaatc gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa
    31981 ggcagaaagc ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa
    32041 aatcactgaa catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct
    32101 agatatgaca ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa
    32161 aaacggcatg ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata
    32221 tgatgttcga acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca
    32281 aaaagcaatt atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc
    32341 aactcgtgga ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag
    32401 ggacaaatac aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc
    32461 ggatcgtatt gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac
    32521 atctgaaaat gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga
    32581 gttagaaaag ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag
    32641 tgcctgtact ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg
    32701 gttttcagcc catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag
    32761 ggataggtga aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg
    32821 tagctaactc agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga
    32881 tcgtcagtgt ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt
    32941 tatgcgtgat cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc
    33001 gagcattttt tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat
    33061 acgtaagcac atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact
    33121 cttccaatat gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg
    33181 gcggctctcg cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc
    33241 tgctgatgaa gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg
    33301 cttctgagta tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg
    33361 gcgctttggc agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg
    33421 ttcaaacgac ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg
    33481 gatcagcaat cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac
    33541 ttggcatgca gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga
    33601 ttatcttctt tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag
    33661 ggaaaaaaca agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg
    33721 aagggggcga actataatgt cgactatcga attaattgcc ttgatcctta cttctacact
    33781 ggtttattca acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg
    33841 gatcgtaaac gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt
    33901 caacttgacg atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg
    33961 tggcgtcgta ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc
    34021 tgaccatatt atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt
    34081 gatcaaagca tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt
    34141 ttctttccca ggattagcag atattccggt cattggacca attttcttta aaaatacatt
    34201 cttacctgct tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac
    34261 gaaattcggc ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg
    34321 tatcaatgta tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat
    34381 gggcggtgct gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg
    34441 acaagggttc atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat
    34501 gggtgcctca ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc
    34561 agttatttct tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat
    34621 tgtgctggtt gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat
    34681 caaatcaaaa taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct
    34741 cgcccttttt gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa
    34801 cgcgtacatc tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag
    34861 ttcggtgatg ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt
    34921 ccacatttag agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg
    34981 aaagatcatc aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg
    35041 acaggccact gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat
    35101 ggattccctg atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt
    35161 aacaaacctt atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca
    35221 ggcgatttaa ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa
    35281 atcattcctt tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat
    35341 gatccgtata tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc
    35401 acacgaacaa gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat
    35461 tctttgaaag aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac
    35521 ggacaaggaa tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg
    35581 ctgaaagtta tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat
    35641 gcattatacg gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac
    35701 ttacgaattc cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc
    35761 gatcacggaa acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta
    35821 ttggtttaca gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat
    35881 atttcagcaa cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc
    35941 ttgaaattat taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga
    36001 tgttacaaga aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt
    36061 tgattctagg ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt
    36121 cttatgatga gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag
    36181 tttatgggtc tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg
    36241 aaggtcattc catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc
    36301 attcagtcat tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt
    36361 tgatgctgat taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg
    36421 aagatgcaat gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag
    36481 caacagcaaa agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg
    36541 gctattctgg accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag
    36601 ccgatgcagt agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa
    36661 aagtgttagg aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc
    36721 atgaagaagt tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag
    36781 aaacattgac attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa
    36841 gaaggcgaga tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt
    36901 gcggagactt ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt
    36961 accggcaaat ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca
    37021 gccaccatct atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta
    37081 ggtacatgcg gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt
    37141 gcagcgacca gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc
    37201 agtgatttca atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt
    37261 catgtaggaa atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc
    37321 caattagctg aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta
    37381 ggcgcgaaat accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc
    37441 ggtgaagaaa caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga
    37501 ttggaaacag cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata
    37561 agaacatcca agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa
    37621 atgtaagctt ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc
    37681 acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg
    37741 agaagttggc aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca
    37801 gtcccttttt tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt
    37861 taattcataa acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga
    37921 gataccttcg atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac
    37981 agttttgttg tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc
    38041 taatgtcact ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg
    38101 acggtcattt gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta
    38161 agaacgacgc cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt
    38221 caaaccttgt aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac
    38281 ccaaagttga tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac
    38341 agaagtgtaa gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt
    38401 tgcttcttcg attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa
    38461 tgcattccat tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc
    38521 ttttaagata ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg
    38581 aagagatttc catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa
    38641 aaaacgaaca gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat
    38701 ttctttttca ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga
    38761 agaaataaat tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt
    38821 ttttgcatcg atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc
    38881 aactaatgta cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg
    38941 gaaatagatt tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag
    39001 cccgcgatct ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg
    39061 atgaagttgg caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa
    39121 atgaacagca gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca
    39181 accaaagtca gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg
    39241 tgcataacca ataattttca tggtgattcc tttctagcag tgattttcta actggatata
    39301 acagtaaaaa tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg
    39361 tcttttttta ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat
    39421 ctcaacgcct ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg
    39481 ttctactacc ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac
    39541 ttctagatgc agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc
    39601 gtctgtacgc aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga
    39661 gccataaggg atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga
    39721 agaatcaacg atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa
    39781 agcagcgccg ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat
    39841 tgtcaaatcg actacgggga cttcatcaat actctttaac ggtattccta atttttccgc
    39901 ttgttctttt gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat
    39961 acggcgacca atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat
    40021 catcccgtcc tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt
    40081 tgcgtccacc tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac
    40141 ggtaaaaaga taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc
    40201 ttgttgacat gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct
    40261 gtgaagaaac gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt
    40321 tattttttat cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga
    40381 aggaggaaac aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag
    40441 gtggaaaaat ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa
    40501 actaacgtaa actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct
    40561 aaaaaaccga actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa
    40621 gttactgctt atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta
    40681 cgcggtggtc gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta
    40741 gatactgctg gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct
    40801 aaagcttaat tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac
    40861 tatgaacaat atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac
    40921 gtgatgtttt accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg
    40981 taatggttga cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga
    41041 tcaaagaatc tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc
    41101 aacctgttct tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg
    41161 aagttcgccc tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct
    41221 tgcgcggtga acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca
    41281 acacaggtgc ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg
    41341 cgtttgctca ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct
    41401 cagatagtgt ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga
    41461 ccagagaatt ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg
    41521 gtaaaacgac tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg
    41581 aaactcatga aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta
    41641 cgatcacttc tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca
    41701 caccaggaca cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg
    41761 ctgtaactgt tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc
    41821 aagcaacaac ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg
    41881 ctgacttctt atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa
    41941 tccaattacc aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga
    42001 aggctgaaat gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag
    42061 aataccgcga attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg
    42121 atgaagaact tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag
    42181 aaggtatccg ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat
    42241 ttaagaacaa aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt
    42301 tagatatccc agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg
    42361 cagacgacag cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag
    42421 gtcgtttaac tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa
    42481 acgcaacaaa aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc
    42541 gttcagaaat ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca
    42601 caactactgg ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat
    42661 tcccagaacc agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa
    42721 tgggtgtggc tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg
    42781 tggaaacagg cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg
    42841 accgtatgcg tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc
    42901 gtgaaacttt ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta
    42961 aaggtcaata cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg
    43021 aatttgaaaa tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa
    43081 ctggtttgaa agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca
    43141 aagctaaact ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg
    43201 ttgctgcttc tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac
    43261 caatcatggc tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg
    43321 taactgctcg tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg
    43381 ttcgtgcgat ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta
    43441 ctcaaggtcg tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag
    43501 tacaagaaga aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat
    43561 agtcctgcaa agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa
    43621 ttatcgatga tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata
    43681 aaaaatatat tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt
    43741 ctaaaccaca cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa
    43801 cagctgcaat cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc
    43861 aaatcgatgg tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg
    43921 agtatgaaac agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg
    43981 ttaaaaacat gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg
    44041 ctgacggccc aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc
    44101 cttacatcgt tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat
    44161 tagttgaaat ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc
    44221 ctgtagttgc tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa
    44281 ttcttgaatt aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca
    44341 aaccattcat gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta
    44401 caggtcgtgt tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg
    44461 ctgaagaaac ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact
    44521 acgctgaagc tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc
    44581 aacgtggaca agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag
    44641 aagtatacgt gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc
    44701 gtccacaatt ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa
    44761 ctgaaatggt tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg
    44821 ctatcgaaaa cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg
    44881 tcgttacaga aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg
    44941 acgtaatcgc tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca
    45001 ggatcaggaa aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt
    45061 attttctaaa tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg
    45121 tgagtttata tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta
    45181 atcagaatga tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca
    45241 cgaacgagcg tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga
    45301 gggaacaaga tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt
    45361 ttagatcaat cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct
    45421 ggtccaattc cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa
    45481 tacaaagatt cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg
    45541 aacccaacac caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac
    45601 atcgaaatca aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga
    45661 atcttaggga aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca
    45721 gtaactgttg tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat
    45781 ggctacgaag ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct
    45841 gcgaaaggtc atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa
    45901 aatgttgagc taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca
    45961 ggagacatta ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa
    46021 cgccacggac aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg
    46081 tcaatgggtc cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg
    46141 ggtggcaacc gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat
    46201 gttatcttga tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca
    46261 gctgtgaaag ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca
    46321 ttattcaaac aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga
    46381 attgaaccta atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga
    46441 caaggaacac acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg
    46501 cgtcaaaaag gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga
    46561 ggtggcgtag tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt
    46621 cgtcgtttag caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca
    46681 atcgaaggct tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac
    46741 ttatctatcg actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta
    46801 tcagcacgta acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac
    46861 gttgtatcaa atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg
    46921 cttgcataat gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc
    46981 ttgccatgga tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag
    47041 taaaacaagc ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg
    47101 tacgtgcgaa attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag
    47161 cgatcgttac attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag
    47221 cactaataga taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc
    47281 tacctcaaat ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac
    47341 acctgaaaaa tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg
    47401 catcactgta cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa
    47461 acgtaacaaa gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc
    47521 agctaacatc gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa
    47581 aggactagaa gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa
    47641 tgctcttcca ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc
    47701 tggtaaaggt ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga
    47761 aggcaaatac gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg
    47821 ccgtgctaca atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc
    47881 tggacgctct cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa
    47941 tgatcaccca cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc
    48001 tccttggggt caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa
    48061 acttattgtt cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga
    48121 gaggaggttc accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat
    48181 gaaaaaagtt gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg
    48241 ccgttcaaca gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa
    48301 acatgtacca gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc
    48361 tacaagaact tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg
    48421 gaggataaat ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc
    48481 gcacttcacc tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag
    48541 atgcaatttc aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat
    48601 tgatgtcagc agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag
    48661 taagcgaagc ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag
    48721 gatcagcttc tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat
    48781 aaggagggat aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc
    48841 cgcgactggg atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat
    48901 ttaagaatcc gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa
    48961 atcgaacgcg caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt
    49021 attggtaaag gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt
    49081 aaaagaatcc atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta
    49141 ggtgaaggaa tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa
    49201 gccatccaac gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt
    49261 ctaaacggag cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat
    49321 actttacgtg cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta
    49381 ggagttaaag tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa
    49441 ggagggaaat aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa
    49501 aaatgcgcgg ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag
    49561 ctgttgattc acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc
    49621 gttacatgaa acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg
    49681 ccaaagcaat tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac
    49741 cagtaaaacg tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg
    49801 aagcgttacg tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg
    49861 aaatgggtgg tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg
    49921 cttgatcaag aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca
    49981 ggtcaattag aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa
    50041 actgtgttgc gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa
    50101 ggaagaaatc aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca
    50161 attaccgttg ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat
    50221 tctaagaaat acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga
    50281 attatggaaa ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa
    50341 gaagcagtta ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa
    50401 aggaggatac acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc
    50461 gcacgtgaaa ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc
    50521 ggtgatgtga tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt
    50581 gacgtcgtta aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca
    50641 tatattaaat ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga
    50701 acacgtatct ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt
    50761 tcactagcac cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt
    50821 atgtttgtta aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa
    50881 ggcgttgtac tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc
    50941 gttaaaaaac accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa
    51001 gcgccaattc atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt
    51061 ggctacaaag aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta
    51121 gataaataaa agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat
    51181 cttaaagaag taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca
    51241 cctaaagttg aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa
    51301 aacttagata aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca
    51361 aaagctaaaa aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa
    51421 gttacattgc gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta
    51481 ccacgtgtac gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat
    51541 actttaggta ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa
    51601 gtacgtggta tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag
    51661 ttgttgacac aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct
    51721 aaaaaatcaa tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact
    51781 cgttgcgaac gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt
    51841 tgcttccgcg aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa
    51901 aaagtaaatt cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag
    51961 attttctaac tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg
    52021 catcaaaaat taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg
    52081 ttgaatacat cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa
    52141 acggcgaacg tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg
    52201 tcaaagctga cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt
    52261 ctgaaggtgt tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg
    52321 cttacgtatg gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga
    52381 aataaagtcg ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca
    52441 gttaaaggac caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc
    52501 gaaggaaacg aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat
    52561 ggaacaactc gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa
    52621 gcgttagaac taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg
    52681 aacgttggtt actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta
    52741 ccagctaaca cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct
    52801 gcaaacattc gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt
    52861 ggcgaatatg tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca
    52921 tagaagccag cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt
    52981 ttacttgtgc cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa
    53041 taaaaataaa gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa
    53101 gagacatcgt cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt
    53161 ttttcgttct aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct
    53221 agcaagtgcc tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca
    53281 agctgtcggt aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt
    53341 tgaccgtggt ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga
    53401 aaatggacta gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa
    53461 catttggaat tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt
    53521 ggacgtcgtc tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtagga
    53581 tttggtacag gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg
    53641 aagaaaaact tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt
    53701 gcttttagtg gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct
    53761 ggtggaccag ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct
    53821 ttaggctcaa atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg
    53881 aaacgtgcag aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa
    53941 ggaggacaac aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc
    54001 ctcaaaacca acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg
    54061 ttaagccttc taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg
    54121 ttgaagaaat ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg
    54181 aaacttcatg aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt
    54241 ggtacttcat ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt
    54301 tcaggcggcg gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta
    54361 ccaaaacgag gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta
    54421 ttgaaccgct ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc
    54481 gtgaaaaacg aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta
    54541 actgtgaaag cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga
    54601 tcaatcgagg tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta
    54661 gatcgaaaat cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta
    54721 ctgtaccagg cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca
    54781 tgttgaactt ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt
    54841 caccatacat tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat
    54901 ttgttgaatg gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat
    54961 atctgacatt agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat
    55021 acgctcaatt aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga
    55081 ttctaacagc cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta
    55141 tcggaaatgg cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta
    55201 tcagagaaat ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg
    55261 ctatttttgt ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt
    55321 tccaacaagc tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta
    55381 caagcagcta tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta
    55441 gttcgtttat tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg
    55501 aaaactggta caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga
    55561 tttatacgat tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg
    55621 agaaattagc ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta
    55681 aggggactga agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct
    55741 tccttggttt agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat
    55801 caatcggatt aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga
    55861 aacagttaga aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg
    55921 tgttgaggtt tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac
    55981 ctcattttaa tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat
    56041 gcttatggta ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa
    56101 acagctcttg gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa
    56161 gtaacaaatg gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta
    56221 ttagatggct ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat
    56281 ttgaataaaa aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa
    56341 cgtctagccg gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac
    56401 cctacaaaag ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa
    56461 gatgataaac ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca
    56521 atcttggctt attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc
    56581 gatgctgtat ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg
    56641 acttgcatta tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc
    56701 gacttctaga gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt
    56761 tccgccattt tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa
    56821 agaagatatg attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa
    56881 agttgaacta gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca
    56941 ttacatccgt atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa
    57001 ccgtggccgt attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt
    57061 atcatgaaag taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt
    57121 aaaggacgcg ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa
    57181 ttggaggtgc tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg
    57241 tagtagtttc acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag
    57301 ctgatgctgg tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg
    57361 ctatccgtgc agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact
    57421 tgaacatcaa acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat
    57481 tgcctgttcg tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg
    57541 ctatcgctgg caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa
    57601 aaaaagtgaa tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc
    57661 attctacatt caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt
    57721 ggtcatcagc tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc
    57781 aaatggcagc agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag
    57841 taacagttaa aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag
    57901 gtttagaagt gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc
    57961 caaaacgccg tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg
    58021 aacaagacac ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca
    58081 agaatcgcaa aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa
    58141 agagggtatg ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca
    58201 ggtgctgcca tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa
    58261 ggtgttagag aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg
    58321 tatggccaag aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct
    58381 ggcgatatta tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt
    58441 gtctctgaag gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt
    58501 caagcagatg aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc
    58561 tacacacctg ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa
    58621 gattttgata aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca
    58681 atgagtttgt ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat
    58741 gaagcaaaaa atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg
    58801 gaaatgacga tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca
    58861 ggaatcaata ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt
    58921 aacttaggac gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt
    58981 ttacgtaaag aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa
    59041 ctaggacgca catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta
    59101 atcaacgaac gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa
    59161 aaaatgatca ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc
    59221 gtacgtaatg aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct
    59281 ttacaaaaac tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca
    59341 cgcattttga agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt
    59401 gtctaaaatc acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt
    59461 ggaagatatt tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag
    59521 taagcactca tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt
    59581 tgaaggcata aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata
    59641 gtgttagtag gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga
    59701 aaagataaat tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt
    59761 tacaattgat aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac
    59821 acttgccaaa acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa
    59881 tcaaatattg gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca
    59941 aaatccagac aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga
    60001 aaatcaaggg attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt
    60061 tagaatggct gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg
    60121 tgttgccatt gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac
    60181 cagtatgcta gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga
    60241 agaaagtcaa ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa
    60301 tcggatacta gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt
    60361 ttctgctggt cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa
    60421 gagcgcactg aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat
    60481 ggtggattgg ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca
    60541 ccatttgaac aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact
    60601 gcattagtag ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt
    60661 gttaagccaa caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat
    60721 aataagaatt taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca
    60781 cagctattcg aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc
    60841 agcgaagaag aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa
    60901 agctatttgg aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc
    60961 gctggtgtgc ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt
    61021 gatccccagg gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag
    61081 atcactattg tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc
    61141 tatgtgttgg aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac
    61201 attgaatggc taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa
    61261 ttaatggcta aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac
    61321 gctatcgtcc attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta
    61381 tatgcctgga gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt
    61441 ttattttatc ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt
    61501 tttcacatta ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat
    61561 tcgcccattg atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg
    61621 cggagaaact tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg
    61681 cctctttatt ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac
    61741 tacaccgcct ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt
    61801 acggttccca gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac
    61861 attgatggac gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg
    61921 tgaaggaaac ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt
    61981 cagcagcttc aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg
    62041 tggggaagga agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat
    62101 cattgctttt gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg
    62161 gccgctatct attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga
    62221 caagaaatat tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa
    62281 gaaagaacga aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag
    62341 gagagaaaaa catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg
    62401 gattccaaaa acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa
    62461 aaatggcaaa tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac
    62521 atgcgatcgg gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc
    62581 gtttcgcgct agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt
    62641 cagaagactt ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata
    62701 tagggaaacc acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg
    62761 atttggaaaa aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt
    62821 tttgtgcatc aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg
    62881 aggtaaatga aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata
    62941 agatgatacg gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag
    63001 atagtatccc agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc
    63061 ctgaaggact ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca
    63121 gcttcaagaa ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg
    63181 cttattttcg aagaagctac ttctggaaca ccgtttaagg aagaggtcgt gaaatcagcg
    63241 ttttgacctg agtattagag aaacaaacgg gaaaatagct cctcatattt tgccgtttgt
    63301 tgagctaata ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc gtgagcctgt
    63361 catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct ttgatgaata
    63421 tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct attttttctg
    63481 taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt ctgaacaggt
    63541 tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt gttcttctat
    63601 tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga cataaagaat
    63661 aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt caggcaagta
    63721 actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg cgtctttgaa
    63781 attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt cataaggaat
    63841 agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt ttctgccagt
    63901 ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat aggctacaac
    63961 atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat aaaaacttgc
    64021 agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt gaccagaaat
    64081 gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag aactttctaa
    64141 ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag gcacatggac
    64201 ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga cgccagtcgt
    64261 tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga atgtaaaata
    64321 ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca aattatctgt
    64381 cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg gcaatgcatt
    64441 gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc catatttact
    64501 gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat ccatcagcaa
    64561 agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac ctaatttatc
    64621 caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac cactgtaacc
    64681 atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt aaaacgagtc
    64741 ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat cagtatataa
    64801 actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt tcgtattgac
    64861 cagtgcttca gcagacatga tcaataataa caatatactc agatgattga atgaaagttt
    64921 tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca ctgtcaatac
    64981 aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc atgccaccgc
    65041 aaagagagca gctacgacca aaatgattcc taacaacagc ccacgatcgt cttgttctat
    65101 cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat aggcataacg
    65161 gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg gaacaagata
    65221 aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt tcaacggtac
    65281 tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg cgtaaacgaa
    65341 cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca tgattagatc
    65401 cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct cgccatttga
    65461 ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg ccagtaaaga
    65521 agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca atagacgggc
    65581 gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac tggataaaaa
    65641 caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa cacgatgaat
    65701 ccccaaaatc actaatggaa gataaaaaaa tgcatccagc cacatgatga tctccgaatg
    65761 tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc cccagcgagg
    65821 aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga ccttaagcaa
    65881 agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca ccagtggcgt
    65941 gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta gagaagcatt
    66001 ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg catgaaaatt
    66061 agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag gatagattcc
    66121 gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag ctgctgcgta
    66181 gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt tccaccaaat
    66241 ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa aaagagtcta
    66301 gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg tataacaaaa
    66361 ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt tattaaataa
    66421 aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt caacttttcc
    66481 tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga ccataacgcg
    66541 aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt gtgaacggtt
    66601 gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg taatttcctc
    66661 ctttgccttg atttggagca atagaataat tcagctcata ccagactaac atatcatata
    66721 gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa gaataattgt
    66781 aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg ggtaactgcc
    66841 ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag ttttttaccc
    66901 gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc attgaaatta
    66961 ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc ggtgttgtag
    67021 gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt aaagaaaatt
    67081 actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat gtttatacga
    67141 ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa aaagtgaaat
    67201 acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt gtacaaggtg
    67261 ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg atctgaagga
    67321 ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa atggtccagg
    67381 caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat gtattccctg
    67441 tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga gctaaggcag
    67501 tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca aaaggattgc
    67561 tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt ggattttcta
    67621 agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc ttcactcatg
    67681 gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt ttgacagtag
    67741 ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat gtcgttgaag
    67801 taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca gacttgcttc
    67861 cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg tttgtttatg
    67921 agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat gaaccttctc
    67981 cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa ggtcaaatgg
    68041 cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc ggagaaggac
    68101 ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat ggtataggag
    68161 attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat acagaaaacc
    68221 caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc aaagtcgaca
    68281 acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac gagtttgcga
    68341 aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt aaaggcgtcc
    68401 aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa acaatgaatc
    68461 caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa gtgattgtct
    68521 tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta gcagatatcc
    68581 cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg ctttcattca
    68641 atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg tctagcgttg
    68701 tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta gagatcaaag
    68761 aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca gatatcacag
    68821 caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc gtaacgatct
    68881 tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa ctaacagaaa
    68941 aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat ccttatctat
    69001 tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca ttcataaaag
    69061 gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt aaaggaggga
    69121 ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag tcggagaaaa
    69181 aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac tgacttatta
    69241 tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg atcaagaaaa
    69301 ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg gttataaaaa
    69361 aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt ctttttttaa
    69421 tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat acggtaaatg
    69481 ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa caatggatga
    69541 cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag ttgatctaat
    69601 caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa acaaccttgt
    69661 ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt ttccaaaaga
    69721 ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct ttttatttca
    69781 aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt tggagatcct
    69841 ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac tgacaaatgc
    69901 acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc atatgcagcg
    69961 acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg cgttatacgc
    70021 taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct tggcacaaca
    70081 acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg cattgattac
    70141 ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc aaggggaaat
    70201 taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc agaatttagg
    70261 tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag tacttcgtga
    70321 aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta gaacattagc
    70381 tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag ctggacgtat
    70441 cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg attggacgaa
    70501 aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg aagaatcaga
    70561 agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac tatttgcacc
    70621 aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag aagtaatcat
    70681 ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa ttgaagtagg
    70741 ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat ttggattggc
    70801 acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct actgtatctt
    70861 agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga cagagaccac
    70921 caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg aagtatttgg
    70981 cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg atggaaatgt
    71041 tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt ggcagatgct
    71101 tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata atcgttattt
    71161 cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg aaacaatgaa
    71221 aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag aaggcgtggc
    71281 tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag aagcagaaat
    71341 caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg aaaaaatcaa
    71401 tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa tggtccttgc
    71461 tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga atacaggcgc
    71521 gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac gccctggctt
    71581 gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc tggatcttgg
    71641 cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag gttcttttta
    71701 tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca acggaacaga
    71761 agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga atgaaacaag
    71821 cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg ctgatgtagt
    71881 ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa cagcaatgaa
    71941 tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa aaatgggcgc
    72001 tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt ccaaacatgg
    72061 cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag caacaggccc
    72121 cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag atgtagttgg
    72181 acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct gaagcgatcc
    72241 gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag ccatggtgta
    72301 ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa gaagtattta
    72361 acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa gtgacggatg
    72421 aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa ttcgttttag
    72481 agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa attgaaacag
    72541 tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata aaagcaaaga
    72601 aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt gacacgtaaa
    72661 agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt aaagcggttt
    72721 tctatataat tattaataat tcattacaca aagataagaa taacctttgt tataaaacga
    72781 tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa gcagagaggg
    72841 gtattcgatt gtccgataac caattattag aagttcagaa cctacataca ggattccgac
    72901 tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac aaaaacgaga
    72961 ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact acgattatgg
    73021 gattacttga tcctaataac acaaaaatta caggtgagat tttatataac gatctgaatt
    73081 taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc ggaatgattt
    73141 tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag atcaaagaag
    73201 gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca ctagaattgc
    73261 tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc catgaactat
    73321 caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa cctccaatcg
    73381 tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag attcttgatt
    73441 tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact catgacttag
    73501 gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag ttcgttgaag
    73561 tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc tctttactga
    73621 actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa ggtgtcgttc
    73681 cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt ccatggatac
    73741 cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac cacttggtac
    73801 gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg tagatgacag
    73861 aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga ttcttcaatc
    73921 gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa aaaggaaaga
    73981 catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa gccgttgtgg
    74041 gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta acgaagcgaa
    74101 gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa gattcaatgt
    74161 ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc cgaaattttg
    74221 aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat atcgttggga
    74281 tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa cgtcaacgtc
    74341 taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat gaacctgtat
    74401 ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga atacagcaag
    74461 aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa cacatgtgcg
    74521 acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga gaagacattt
    74581 ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg caaatcgatg
    74641 tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag tatatccaaa
    74701 accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg atcacaacta
    74761 cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga ttctgcgacg
    74821 tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct tattagccca
    74881 agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc cggcagtgat
    74941 cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt acttccgttg
    75001 gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac gctctgttgc
    75061 tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga cagttgtcct
    75121 tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa attcaatctt
    75181 ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat ttatcttcgg
    75241 cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa gtggatcaca
    75301 aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga aatatattct
    75361 gttaccatca attacccaag catttttggc gactgccgtc acaatccaat atctgcgaag
    75421 tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca aaggggtacc
    75481 gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga tggcttctca
    75541 aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa agatttttgg
    75601 ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact ataccgtgat
    75661 cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac tttcagatat
    75721 catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag aaaggagaat
    75781 ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc tatggggata
    75841 cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt aggtttgcta
    75901 gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga caaagtgatg
    75961 tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca aggacaaaag
    76021 ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat cataggtgct
    76081 agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat cggggttgga
    76141 ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat gcggatcgtt
    76201 gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc gattatttcc
    76261 agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt agctaaagcc
    76321 cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag tgcctcaaaa
    76381 acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa tctaagttca
    76441 ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga gacaactttg
    76501 actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt gatcggttat
    76561 gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc atcaatcctt
    76621 attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg ttctgcagat
    76681 gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga agaaaacgat
    76741 ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg gcggaggtac
    76801 agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat taacttttcc
    76861 aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag ctgcggtcgc
    76921 aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt catatgatgc
    76981 agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt tcagaatcac
    77041 agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga caatcaaagt
    77101 aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg tgattttccc
    77161 ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca ctttccgtaa
    77221 catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg gaatcaaaaa
    77281 aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca tgcttcaatc
    77341 gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg tagcaatcaa
    77401 agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc cttattacat
    77461 gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact actggaatgg
    77521 tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg caactgaagc
    77581 attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt acgataccta
    77641 taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata cttatctagg
    77701 attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc cagattcaaa
    77761 aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata atgcagtagg
    77821 tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc cagtattcca
    77881 gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag cgaaaaaact
    77941 attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag acaaagatgg
    78001 aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc aaccattggc
    78061 agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca caacaggtcg
    78121 tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg aaattgatgt
    78181 ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat ggggaccaaa
    78241 tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga tcaacgatat
    78301 cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa aatggcaaca
    78361 atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag tattgccagt
    78421 caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat gggcaaatgt
    78481 ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag ggcgatgtcc
    78541 tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca aggcgctgat
    78601 ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta agtcaaattt
    78661 atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga aactaaacga
    78721 atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac cttttgaccg
    78781 aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa aatatccata
    78841 aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa ctataacatc
    78901 gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta tgtgaatgag
    78961 catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga tgccgtttta
    79021 gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga aggaaaattg
    79081 acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc caaagaatgt
    79141 cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg acgtacgcga
    79201 ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct tgaccaggga
    79261 ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa agcaggtgct
    79321 ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa atcaggtgat
    79381 gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg agtattttgg
    79441 atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc gaaaaaatta
    79501 gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt gagggaaagc
    79561 tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca agacagtcat
    79621 tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa aaagcaatat
    79681 tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc gaggcggaaa
    79741 aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata ttgcagaagt
    79801 cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg agatcagtgt
    79861 aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac aaagctgcag
    79921 attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat cgttctcaat
    79981 catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc gtcgtgggat
    80041 ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag cagaacagaa
    80101 gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg aattggaaga
    80161 acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac ggctaaaaga
    80221 aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag caaaaaaaga
    80281 ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca aactatctga
    80341 gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg cgcaagccga
    80401 tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac tgaagcagac
    80461 agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa gctcgcaaga
    80521 atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa agcttcaaga
    80581 aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg aagcaaatct
    80641 cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat tattggcaga
    80701 attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa acgaactgaa
    80761 gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt tagccaagca
    80821 atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat tgacacaaaa
    80881 gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa tgatccaaca
    80941 aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt atcaattaat
    81001 gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc aagaaaacta
    81061 ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc tttcgggtat
    81121 tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag ctatcgaagc
    81181 agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg ctcggcaagc
    81241 catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac tgacgacaat
    81301 caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag aagggtttat
    81361 agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg ttcaaaacct
    81421 gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg cgcaaacgat
    81481 ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg gaggatccat
    81541 gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa atcaagaatt
    81601 gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac aagaaaaaaa
    81661 agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag ttttgcgtac
    81721 acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac aaaacatcat
    81781 aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga cacgtgaact
    81841 gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca aacaaacaga
    81901 tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc aagaaagcga
    81961 ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac aagcagatct
    82021 tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg cccgagtcca
    82081 aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga cattgacagc
    82141 agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta acgaattatc
    82201 tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc gagatagaag
    82261 gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg agcaaaaagc
    82321 acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa tgattttaga
    82381 taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag cttcccaaga
    82441 ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct taaaagaaca
    82501 gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac aagtcagtga
    82561 aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa accaattgtt
    82621 tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag tatttgaagc
    82681 tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta aagctgaatt
    82741 agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag tacaacctcc
    82801 tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac ttacagccat
    82861 cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct tagatgaggt
    82921 agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga gcgatttcca
    82981 agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg cagcagatgt
    83041 actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg tacggatgga
    83101 agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa aatgatcaaa
    83161 ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat ttcagatgag
    83221 aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct atgtacagga
    83281 cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga tgaaggtgac
    83341 tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga aatcatggaa
    83401 aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca gcaattggat
    83461 ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc cccaaggaag
    83521 caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga tataagcgat
    83581 attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga agaattagat
    83641 cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat caaaacaaga
    83701 agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat ttctttattg
    83761 gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga ggaaaatgat
    83821 ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt gcctttcgtc
    83881 aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc caaagtgatc
    83941 caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa tcaagcgtgc
    84001 ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg acaagggttt
    84061 agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca attttcgaac
    84121 agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag atgtaggttt
    84181 tgaaacagcg atacgaatca ccgaagcatt acgtcaagaa gtgaaactca gaaatgcgaa
    84241 aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct atgaagcgga
    84301 aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag ttattttgtt
    84361 tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc atcagttcaa
    84421 aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg gagcaatcga
    84481 ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca atgcaggagg
    84541 cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc aggcagatgt
    84601 tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga acgaattaga
    84661 aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa cacttcttgt
    84721 attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca aagaaacaac
    84781 agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg gtatcgtact
    84841 tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg aaggaatcga
    84901 tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag gattactaaa
    84961 agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc tccttgtttg
    85021 aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact tatttgtaag
    85081 cggttctcaa acaatttcgt tctttttctt agactttttg attataatta gattcatatg
    85141 aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca atgcgcgccc
    85201 ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg atcttgcagg
    85261 aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc acccctatat
    85321 ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg attctattcc
    85381 cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta taccgaaaga
    85441 agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg aagagatcat
    85501 tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag caaaagaata
    85561 cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg gcgatgagtt
    85621 gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat tcaaaacaga
    85681 actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca cttatttatt
    85741 cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc cgcaagaacc
    85801 tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg tgaaagtttc
    85861 ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag aagggaaact
    85921 ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga aagtcgcaga
    85981 tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga atccttatgc
    86041 aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga tgtacatgtt
    86101 atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga ctcgaaataa
    86161 caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag gtagagaaat
    86221 tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc tttatttagt
    86281 agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga aactctatca
    86341 agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc aatattataa
    86401 agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac tttctactca
    86461 gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag atgagtcgga
    86521 tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg caaacatgac
    86581 aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa cgaaaaaagt
    86641 cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca tggaagaagc
    86701 ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta aatcaaccaa
    86761 ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt atcaagcagg
    86821 tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta tgccgggaac
    86881 ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc gagtccctgc
    86941 taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa aaaatagtga
    87001 ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag gtgaattaga
    87061 acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag ccaatcaaat
    87121 tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg atatgactga
    87181 tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac taggagctaa
    87241 gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa ctgataaaaa
    87301 agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg tttatccttt
    87361 tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc ctgaagtatt
    87421 ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc aaaagctttt
    87481 tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca gaagcttttt
    87541 ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta ttttttttcg
    87601 atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc gaattcctca
    87661 ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt cgttgctagc
    87721 tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat ggaagcatct
    87781 ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat catttcagca
    87841 acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg ctgttcttca
    87901 gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac atcatcttgt
    87961 gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc atattcccaa
    88021 taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact taaaataaga
    88081 atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac tagtagcatt
    88141 attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac aattgtcaga
    88201 actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt tgccacgaac
    88261 gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca tgcaacattt
    88321 gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg cgcgtttagg
    88381 tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat ccttgacagc
    88441 attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat tgttcctcca
    88501 gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca ttggttcagt
    88561 tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat ggcttcaagg
    88621 gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg ttccattgtt
    88681 gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg aatcgtttgc
    88741 agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct tagtatcatt
    88801 ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag tgatcattcc
    88861 gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg taactgcttt
    88921 agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga tttttcctta
    88981 tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc tttatcttct
    89041 gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt atgcttgttc
    89101 ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac tggcattttg
    89161 catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta gctgtcagca
    89221 gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct tcagtattgg
    89281 gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc ggaggagtga
    89341 cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg atggtcgggc
    89401 tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt tttttattac
    89461 tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt ttacaagtca
    89521 tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc tttggcaata
    89581 tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg tacctgttat
    89641 ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca gtaaacctcg
    89701 ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt ttgacaggga
    89761 catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca aatatcagtt
    89821 atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt ctggtagcta
    89881 tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg aatacaacag
    89941 tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg attcgcgaaa
    90001 ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg gaaaatcagt
    90061 ggttaaagat gtacagttaa cgattcctga aaagaagttg actgctttta tcggtccaaa
    90121 tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa aagatacagg
    90181 tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat tagccaaaaa
    90241 attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga aagaattagt
    90301 agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg aggaaatcgt
    90361 tcaggaatca ctggaacaca ttgggttaga agaaatagcg gatcaatcga ttgacactct
    90421 ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag acacggatta
    90481 tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc aaatcatgca
    90541 gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc ttcatgatat
    90601 caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac agttatttac
    90661 gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat acgaaatgga
    90721 catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa actaacatta
    90781 ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca tttggtttag
    90841 cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc agcacacaaa
    90901 ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg ccaaataatc
    90961 cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct cttggtgttg
    91021 gagataaggt agttggagca gctacaagca gccttcctga gtatctttca tcctataaaa
    91081 aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat cagcttcagc
    91141 cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta agtcaaattg
    91201 ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc cagcaaaatg
    91261 tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa ttagaggaat
    91321 tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa aaagcactag
    91381 tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga ttcggtttca
    91441 tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc actcacggtc
    91501 aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt gtagtagaca
    91561 gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat gaactggtag
    91621 cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat gtctggtatt
    91681 taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat caagcattta
    91741 aatagcataa ataacagagg attaaactct catactatgt aacaataatg tttcttacat
    91801 tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt aaaatcgtat
    91861 tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg tgaattcatt
    91921 atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg tgatccattt
    91981 tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga aacttagata
    92041 aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga tgttccatct
    92101 gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt ttctgtccag
    92161 cgttcttatt actcaaaaca aatcgcagtt gtcacaatct cttctaaacg atgttccatc
    92221 tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat tttctgtcca
    92281 gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac aatgttcaat
    92341 cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt aggcatgtgt
    92401 ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg cgggaagctt
    92461 actccaccgt tttagtaatt gatagaaata actctcttct gctttgattt tatactcgct
    92521 taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa tatccaatgc
    92581 tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac cctcgatatt
    92641 ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga ttcctccaaa
    92701 gaagtctttt atttgataag tttactctac cgaagagttg ttaataatcc gtgaacaaaa
    92761 agtaattctt tttccaatag ttgttaaagg ttttttattt tttatagtat tttttgttat
    92821 ttaagaaagg aataaggtta aacaaataac aggttgcttt ttgggtcttt ttccgttcaa
    92881 gaaactgaac gaagaaaagg gaaagttgtc tcttttgtga taagagaaat cataataaac
    92941 gaatgactta ctttccaata aattgagaac agtcagaacc agacaaatta gttgcatctg
    93001 atgaataaag tgattattct atgacatgag gtgatacaga tgaaattaga agtgacaaaa
    93061 gaagcacaag aagtattgaa gaataaatta gaagcagacg atcaactttt attagatatc
    93121 gaaaacggtg acggtccatt tgcagaaagc caagtcagtt gccaattgga tacggcattt
    93181 cgattgatca ttgtcaaaaa agatacacaa acagatctaa gtctttattc tgtagtggct
    93241 gatacaccag ttggaccaat caaaatcaaa gacagtgcaa tactttacat ggatgatcca
    93301 tccacacttg ctttagaacc aacttataat agtttacaat taaaaggacc aagcggcttg
    93361 agaaaaggca acttgcaagt tgttcgaaaa gactagaggg ataaaatggg aaaattggcg
    93421 atcatcagcg acctacatgt ggacatcaat aaattcggcg aatcagagct gatgcagctt
    93481 tggcaagttt tgcaaaagca caagatcact cggcttcatc tagccggaga tacggctaat
    93541 aaagtagacc gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt atctacgaca
    93601 tttcatttcg gcaatcacga gttggcagat gtgcccaatg aacagatgat ggaccatttt
    93661 ccagacccac attttttaaa tgaacggtat attgctttaa atgagcagac cgttctttta
    93721 gggatgaatg gctggtacga ctatcagttt tccgaattga aagattacga ggcaatcgta
    93781 cgaatgaagc gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac agatctcgag
    93841 gtcaatgcag aaatgcttgc agctgcaaaa aatttgctag accagctgga agcaaaaaaa
    93901 cttgaggtga ttttatccac tcatttcgtt cctaaacggg catttatcat gtatcaatct
    93961 gctccttatg agcgttggaa caaattaaat gcatttttag gatcagaatc attcggagaa
    94021 ttacttgacc gttattcaaa tatcaaacaa gtagtttttg gccatacgca tcgtcgcttt
    94081 gaagataaat ccatcggtca cacgatttac agctgcagac cttttggtta ttattatgaa
    94141 tggcagctga cccgagattt tgtcttgaaa gaacagttgc tagacagcta tgatcctatg
    94201 aaattacgtg tcctcttgcg tgcccatcac ccagcttttc aggcctatca aacacaacat
    94261 ttgcaagagg aatttgaaca agcgatgaca atcgttccgt attgagacag cattagtaat
    94321 gtgtaaaaga aaataccttg taaaacataa ggataagtaa gagcagtaga tccatttatc
    94381 gtggatatgc tgcttttttt gcggaaaata atcagcgaat gtttatttga tcggatgatt
    94441 tgtaactcgc agagtactag atgcaagcgt gtattctttt tttgaacgat aatcacaaaa
    94501 aaaaatataa tatacatttt ttatttaatt ataattaata ttgattgaag tctaggcagt
    94561 caagtcgaga gt
//
LOCUS       DAFEML010000005        83709 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFEML010000005
VERSION     DAFEML010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 83709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.005"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            85..972
                     /locus_tag="LP468_000422"
     CDS             85..972
                     /locus_tag="LP468_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2079987.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LP468_000423"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LP468_000423"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL2079988.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LP468_000424"
     CDS             2274..2720
                     /locus_tag="LP468_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2079989.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LP468_000425"
     CDS             2993..4345
                     /locus_tag="LP468_000425"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL2079990.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LP468_000426"
     CDS             4516..4803
                     /locus_tag="LP468_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079991.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="LP468_000427"
     CDS             5029..5472
                     /locus_tag="LP468_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2079992.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="LP468_000428"
     CDS             complement(5478..6662)
                     /locus_tag="LP468_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBL2079993.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="LP468_000429"
     CDS             6930..7628
                     /locus_tag="LP468_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2079994.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="LP468_000430"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="LP468_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL2079995.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="LP468_000431"
     CDS             complement(8438..8971)
                     /locus_tag="LP468_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2079996.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="LP468_000432"
     CDS             complement(9268..11649)
                     /locus_tag="LP468_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2079997.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP468_000433"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP468_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL2079998.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="LP468_000434"
     CDS             12350..12889
                     /locus_tag="LP468_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL2079999.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="LP468_000435"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="LP468_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL2080000.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="LP468_000436"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP468_000436"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="LP468_000437"
     CDS             13996..15162
                     /locus_tag="LP468_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL2080001.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="LP468_000438"
     CDS             15208..16704
                     /locus_tag="LP468_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL2080002.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="LP468_000439"
     CDS             16785..17468
                     /locus_tag="LP468_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2080003.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="LP468_000440"
     CDS             18113..19303
                     /locus_tag="LP468_000440"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL2080004.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="LP468_000441"
     CDS             19405..20358
                     /locus_tag="LP468_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL2080005.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="LP468_000442"
     CDS             20427..21776
                     /locus_tag="LP468_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080006.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="LP468_000443"
     CDS             complement(21959..22282)
                     /locus_tag="LP468_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080007.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="LP468_000444"
     CDS             22411..23574
                     /locus_tag="LP468_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2080008.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="LP468_000445"
     CDS             23644..24993
                     /locus_tag="LP468_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2080009.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="LP468_000446"
     CDS             complement(25038..25469)
                     /locus_tag="LP468_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080010.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="LP468_000447"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="LP468_000447"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL2080011.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVCEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="LP468_000448"
     CDS             28699..29295
                     /locus_tag="LP468_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2080012.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="LP468_000449"
     CDS             29417..30565
                     /locus_tag="LP468_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2080013.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="LP468_000450"
     CDS             complement(30603..31016)
                     /locus_tag="LP468_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL2080014.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="LP468_000451"
     CDS             31095..31526
                     /locus_tag="LP468_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL2080015.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="LP468_000452"
     CDS             complement(31625..31858)
                     /locus_tag="LP468_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL2080016.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="LP468_000453"
     CDS             32041..33711
                     /locus_tag="LP468_000453"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL2080017.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="LP468_000454"
     CDS             33858..34244
                     /locus_tag="LP468_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080018.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="LP468_000455"
     CDS             34231..34929
                     /locus_tag="LP468_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2080019.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="LP468_000456"
     CDS             34934..35398
                     /locus_tag="LP468_000456"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL2080020.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="LP468_000457"
     CDS             35395..36306
                     /locus_tag="LP468_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2080021.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="LP468_000458"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="LP468_000458"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL2080022.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="LP468_000459"
     CDS             37094..38377
                     /locus_tag="LP468_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL2080023.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="LP468_000460"
     CDS             38390..39316
                     /locus_tag="LP468_000460"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL2080024.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="LP468_000461"
     CDS             39335..40615
                     /locus_tag="LP468_000461"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL2080025.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="LP468_000462"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="LP468_000462"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL2080026.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="LP468_000463"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="LP468_000463"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL2080027.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="LP468_000464"
     CDS             44940..45716
                     /locus_tag="LP468_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL2080028.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="LP468_000465"
     CDS             45713..46645
                     /locus_tag="LP468_000465"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL2080029.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="LP468_000466"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="LP468_000466"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBL2080030.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="LP468_000467"
     CDS             47365..47994
                     /locus_tag="LP468_000467"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBL2080031.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="LP468_000468"
     CDS             47982..48296
                     /locus_tag="LP468_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080032.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="LP468_000469"
     CDS             48334..48975
                     /locus_tag="LP468_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2080033.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49018..49710
                     /locus_tag="LP468_000470"
     CDS             49018..49710
                     /locus_tag="LP468_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL2080034.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="LP468_000471"
     CDS             49707..50609
                     /locus_tag="LP468_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2080035.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LP468_000472"
     CDS             complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LP468_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL2080036.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52663..53286
                     /locus_tag="LP468_000473"
     CDS             52663..53286
                     /locus_tag="LP468_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080037.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53736..54785
                     /locus_tag="LP468_000474"
     CDS             53736..54785
                     /locus_tag="LP468_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080038.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54782..55663
                     /locus_tag="LP468_000475"
     CDS             54782..55663
                     /locus_tag="LP468_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080039.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55666..56436
                     /locus_tag="LP468_000476"
     CDS             55666..56436
                     /locus_tag="LP468_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2080040.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56715..57569
                     /gene="aroE"
                     /locus_tag="LP468_000477"
     CDS             56715..57569
                     /gene="aroE"
                     /locus_tag="LP468_000477"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL2080041.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57747..58910
                     /locus_tag="LP468_000478"
     CDS             57747..58910
                     /locus_tag="LP468_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2080042.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59027..59437
                     /locus_tag="LP468_000479"
     CDS             59027..59437
                     /locus_tag="LP468_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2080043.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59611..61839
                     /gene="topB"
                     /locus_tag="LP468_000480"
     CDS             59611..61839
                     /gene="topB"
                     /locus_tag="LP468_000480"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2080044.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62010..62294
                     /locus_tag="LP468_000481"
     CDS             62010..62294
                     /locus_tag="LP468_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080045.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62454..62690
                     /locus_tag="LP468_000482"
     CDS             62454..62690
                     /locus_tag="LP468_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2080046.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62687..63085
                     /locus_tag="LP468_000483"
     CDS             62687..63085
                     /locus_tag="LP468_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL2080047.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63752..64695)
                     /locus_tag="LP468_000484"
                     /pseudo
     CDS             complement(63752..64695)
                     /locus_tag="LP468_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
     gene            complement(64991..65935)
                     /locus_tag="LP468_000485"
     CDS             complement(64991..65935)
                     /locus_tag="LP468_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080048.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66156..67370
                     /locus_tag="LP468_000486"
     CDS             66156..67370
                     /locus_tag="LP468_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2080049.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67392..69407
                     /locus_tag="LP468_000487"
     CDS             67392..69407
                     /locus_tag="LP468_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL2080050.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69490..70863)
                     /locus_tag="LP468_000488"
     CDS             complement(69490..70863)
                     /locus_tag="LP468_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2080051.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70889..71173)
                     /locus_tag="LP468_000489"
     CDS             complement(70889..71173)
                     /locus_tag="LP468_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2080052.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71175..73190)
                     /locus_tag="LP468_000490"
     CDS             complement(71175..73190)
                     /locus_tag="LP468_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2080053.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73369..73674)
                     /locus_tag="LP468_000491"
     CDS             complement(73369..73674)
                     /locus_tag="LP468_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL2080054.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73763..74794)
                     /locus_tag="LP468_000492"
     CDS             complement(73763..74794)
                     /locus_tag="LP468_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2080055.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75001..75876
                     /locus_tag="LP468_000493"
     CDS             75001..75876
                     /locus_tag="LP468_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2080056.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76028..76870)
                     /locus_tag="LP468_000494"
     CDS             complement(76028..76870)
                     /locus_tag="LP468_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2080057.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76962..78839)
                     /locus_tag="LP468_000495"
     CDS             complement(76962..78839)
                     /locus_tag="LP468_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2080058.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78836..80257)
                     /locus_tag="LP468_000496"
     CDS             complement(78836..80257)
                     /locus_tag="LP468_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2080059.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80260..83649)
                     /locus_tag="LP468_000497"
     CDS             complement(80260..83649)
                     /locus_tag="LP468_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2080060.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
BASE COUNT        26765 a        14816 c        17289 g        24839 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta tgcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 tacttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccgatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggtat aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa
    52681 gtagttaaat cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat
    52741 ccaagtaagt attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt
    52801 gcaatgtttt tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg
    52861 tccataccaa ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa
    52921 caaagccggg cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg
    52981 cttgatgttt ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat
    53041 ccgatcgttt atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg
    53101 acatttattt tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga
    53161 ataactgatt ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc
    53221 aaacaattag aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct
    53281 aattgagaca ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga
    53341 acaagtgatg tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa
    53401 ttcaaaaatt cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt
    53461 atcaaaacgt atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt
    53521 attaatggtg agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat
    53581 ctatgctaga catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta
    53641 aagacaatga ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata
    53701 ataaataaaa agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag
    53761 ttgtagtaat tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg
    53821 aaaaagaaag tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat
    53881 acgtgagcca tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag
    53941 aaggattaaa agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga
    54001 gcaagctagc cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa
    54061 tcgcaacacc tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag
    54121 gtgctgtaac ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta
    54181 atgtaacagg tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt
    54241 tgttgccaaa tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat
    54301 accaagtagc acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg
    54361 cggtgccttc cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt
    54421 ttatctatgt tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag
    54481 caaacaaagc aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac
    54541 tagcaacaat cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag
    54601 aacttgcgag tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg
    54661 atacagtgat caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga
    54721 aggaaaaagc caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca
    54781 aatgatcgta tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt
    54841 catgacttat cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg
    54901 tgctgctgtc tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt
    54961 aggcgtaggt gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa
    55021 gataccggtt attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt
    55081 tgtgatgcga acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca
    55141 tcgctttggg ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat
    55201 cttgattgct gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac
    55261 aggagacaac gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt
    55321 aggtttaact ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga
    55381 cggatatgca gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat
    55441 catcggtgaa gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt
    55501 cggcagtatc atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac
    55561 ttatctgaag ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa
    55621 gaaagcactg aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg
    55681 acaatcaaaa atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg
    55741 gatgaaatta accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt
    55801 gctggaaaaa gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg
    55861 atctctttta aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt
    55921 tctcgagttt tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat
    55981 ttgctacttg cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat
    56041 caaaaagaag attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg
    56101 gatactccag cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg
    56161 acgatcacag ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa
    56221 acagctaaag cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt
    56281 ctcatgatca cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc
    56341 caaaaaggga aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc
    56401 gaccttttgc agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag
    56461 tagaaggact tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata
    56521 aacaattaaa catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa
    56581 atagaatatt ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc
    56641 tagacgtttc gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac
    56701 aaaggaggaa taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg
    56761 cttctcacag tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg
    56821 cggtgtattt agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc
    56881 gaacttttga tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt
    56941 atctggatga ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg
    57001 aaaagggtcg tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag
    57061 aagctgggat ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa
    57121 aggcagtcac tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa
    57181 acaaccaaac attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt
    57241 gtaagataaa agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa
    57301 gctgtcttct agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc
    57361 tcttagatat aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta
    57421 gagaaacacg tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg
    57481 gcatgttgat ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga
    57541 tccatgtgat tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct
    57601 cgcataaacg gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt
    57661 tttattaaat tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta
    57721 tcagtaagaa acgaggagga accacaatga gtcggatgga tcgctataag gacatccata
    57781 agaaggcgaa acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac
    57841 gaacgcgtat ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat
    57901 ttgaacattt gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac
    57961 aacaaaaaaa taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa
    58021 gaaagcgatc gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag
    58081 gtatctcatt ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga
    58141 cttcagaaac ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg
    58201 gaagtgatac acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg
    58261 atggtccttc ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc
    58321 caggggtagg acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc
    58381 gtcaaacttt agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca
    58441 aatcgtttga aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa
    58501 aagatctgaa tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg
    58561 ttcttttgca gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac
    58621 gccaacagca agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc
    58681 gtgcacctta tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt
    58741 tcttgacgaa aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg
    58801 tgccagtaga cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa
    58861 ttgataatca aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa
    58921 gatcaagaag aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa
    58981 aaacgctttc ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct
    59041 gaacttcaaa aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga
    59101 agcatcaggt atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga
    59161 agaagcaaaa aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt
    59221 tgcagatacg ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt
    59281 catccagaca agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg
    59341 taagattgag atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga
    59401 tcgatttggc atcaactggc agattaacca agagtgacag ctaaagatga atattttctg
    59461 gaaacatcaa gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg
    59521 actatacggt atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc
    59581 cgcaaaaaat taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct
    59641 tcacaagcaa aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat
    59701 gaaatcagcg atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg
    59761 gtagatatgg ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat
    59821 ttgcctattt tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt
    59881 tcgatcgtaa aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat
    59941 cgagaaggtg aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa
    60001 aagaactatt tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt
    60061 aagaatctcc aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag
    60121 aacgctgatt ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga
    60181 aaagggattg atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt
    60241 tatcagctgc aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt
    60301 ttaattacga caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa
    60361 acccaagaag agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac
    60421 ggacggattc ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg
    60481 ctatctagtt tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt
    60541 gatgctgctc aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt
    60601 tacattacag aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt
    60661 ttaggaatag aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg
    60721 aaaaaagttc aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc
    60781 tttgcgaagc tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg
    60841 gctatgtttg ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa
    60901 ttaaagctaa aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc
    60961 atcaagtcaa aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca
    61021 gaagtagaac tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga
    61081 acgttgatca cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa
    61141 attctcaaag aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat
    61201 cttaagcaga agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga
    61261 atcactcttt gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg
    61321 cgctgggaag ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta
    61381 gagaatatca aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag
    61441 gtagactttt cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac
    61501 gatcaattag gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc
    61561 gctacatgct tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag
    61621 ctgactaaaa cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa
    61681 ggttttactg gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca
    61741 atcggttttt cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa
    61801 gaaacatcaa gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg
    61861 aatatttatt ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat
    61921 caagcaaaaa cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga
    61981 aaaaagtgca ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc
    62041 aagcatttct aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa
    62101 cagcatattc accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt
    62161 atttttttca taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg
    62221 tggtggtagc ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc
    62281 aatattttgg ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt
    62341 tgtcattttt tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac
    62401 ttggatataa tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa
    62461 aaatgaaaaa gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag
    62521 aagtaaaaga attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg
    62581 atggttctgt acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt
    62641 cgatcatgaa tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc
    62701 gactaaagaa attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat
    62761 gatcggtgta aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt
    62821 attcaatcaa gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt
    62881 agctaaaaaa catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt
    62941 gtttcttcaa ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat
    63001 cataatgatt accactagtt cattggattt cgattcacta aagtccaaga taaccagtta
    63061 tttacgacaa accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc
    63121 atgtcattaa ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata
    63181 aaaatatgga aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt
    63241 gaatagtagg aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac
    63301 ataatatata ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt
    63361 atcaaaaatc gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc
    63421 agtttttctt actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt
    63481 taatcaaata tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt
    63541 taattaacca cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt
    63601 catatgttca tatgtacgga tacattttcg gaccgattaa ttttaaccat tctgtttatt
    63661 tgcttaccta ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt
    63721 tttaggattt ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta
    63781 aagcacttgt tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa
    63841 cttcacgaac accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt
    63901 cgtattcacc agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag
    63961 cttttacgat acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa
    64021 tgatctcata agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa
    64081 tacgatggtc tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc
    64141 atgcagcaac ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt
    64201 caacttttaa tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag
    64261 taccgataac acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat
    64321 ctactgggtt tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta
    64381 cgatttggcg catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt
    64441 tttggttgat accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac
    64501 ctgaccatac agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt
    64561 ccccttctgc tttttcttga ttcacatcga caatactaat tcattagaga ttccttggtt
    64621 gatcattgca taagcgatac ttgttccaac aaaacctgta ccgacgatta ctactttacg
    64681 acttgttttt ttcatgaata aacagctcct tttcataact atttgttact ttcatgaaaa
    64741 gtatagtctt gtttattcat tttatcaaca tgttaattat aatagttgtt attataattt
    64801 ttgatggaaa cgaattcctg aatacgcata acagataaat gacaaatgtt tacacctata
    64861 tcccctgata atacaaccaa aagtttagaa ctgaaaataa atccaaaaaa attcgctgca
    64921 acgatataat aagacagcaa tcgcacctaa aacaattttc cttcatatgc tttagtgaaa
    64981 gattttcttc ttaatgttta tttctccatt cattgggagt acatgttgaa tacttcttga
    65041 ataatttgaa taaagaagtc gtttgtttat atccgatacg attagcgatt tcttccaacg
    65101 aaaaactcgt ttcttgaatc agttccaacg caaagtcgaa ttttttcttt agaaccagtt
    65161 cttgaaagga agcatcaaaa tacattttca atttattact aagatagacc ggattgtagc
    65221 caaaatgagc tgctgtttct tttaacgtac aagaagtaaa atgcttatcg atataatcta
    65281 atactctaag catctcattt tctgcgcatc catctgctga tgaaaagctt tgttgttcta
    65341 ataaatgagt caattcgatc agtaatagtg atgtatagag atttaacgaa cggatcttat
    65401 gactgtatgt atcaaaataa atcaacagca tattttcaat caaatgcgtc aaacgacttg
    65461 tttttccgcc gcgaaaatga atgaattgtg tatgttcccc tttttctttt gatgcattta
    65521 tcaaaaaaga agaaagtaga ttatttgtgc ttgccaaatg attcaatatc tctgtagata
    65581 aggtttcttc ttttaataag atgttgatta aaatatcctc ttgccctgtg tattcgattc
    65641 tttgagtagc ttctttatca atgatcacca cgtcactttc ttccatctct atcctttctc
    65701 cattaataat ttgtaaacat gtaccgctat acatataatt gatttcaaca aaatcatgtg
    65761 tatgctcggg aacttccgca tatcgacggt gtttactgat atgaatattt ccctgttgaa
    65821 atagatcccc tcggtggatt tttggcggtg tctgaagatg gtaagctaag tttaaatcat
    65881 tgatattcat tccttgttca cgctgcagag tttcgattga ttcttcgtta cgcaaaaaaa
    65941 atgtctaatt cagctagttc caattgactc cctccttttt gtaagcggtt tctttcgctt
    66001 attagttcac gctgtactgc tattatatgc aaagctattt ttggtttcat aaagactttc
    66061 tatggttggg acatgaactt cctgtgattc cgctattgag agaataacca cttcatacta
    66121 tatttttgat aagcgcttac aaaaatgaaa ggaacatgct tatgaataaa aagatgatga
    66181 aattttctct gctgtcagtc tctcttattt tgacttctgc tggtgcagtc acgtctgcaa
    66241 ttcccagtat gtcagctact tatgccacgc gttctttatc tgctgttgaa ttattaacga
    66301 ctgctccctc ttttatggtc actatttttg ttttgattag tagttttatt gctaggaaaa
    66361 tcggacaaaa acaaactgtg atcatcggat tagtgattgc atcgatttgt ggtatcctcc
    66421 ccctcttctc acaaagttac agtattgtct tagcttcaag agctggacta ggtattggct
    66481 ttggattgat caattctttg gcagtcagca tgattgctgc cttttatcac ggagatgaac
    66541 gagcctctat gattggtttt caaagtgcat ttcaaggatt tggtgcagct ttaatgacat
    66601 ttgttgcagg acagctagta cagttcggtt ggcaatatac ctttttagtc tacgccatca
    66661 gcttacctat tcttgtcttg tttgttttgt ttgttcctac acctgaaaca actgaacttc
    66721 aatcgcatgg cacagcccca acaagacaag taatcaaaac gaatcctaaa atgattagtt
    66781 atggtatttt tctcttgctg gtcatcgtgg tatataatgc tgtatcgatt aaattagcca
    66841 cagtcctgac gacttattct ctaggaaacg aaactaatgc agcgaatatc ttaacaatca
    66901 tgcaattggc aagtatggct gccggagttt gttttggctg gcttcagaca aaagcacatc
    66961 gctatatgct tacactttct ttactactga tgggaatcgg ctttgtattg attgccactg
    67021 tgataaacct gtatgtgatt gggtttggtg cgatcctaac aggaatttct ttttcgttat
    67081 tcattcctta cttattcaac caagtaagta tccaagcgcc caagtacgcg gagagtttca
    67141 atacttcaat cttattggtt ggcgctaatt taggtacttt cattgcacca tatggtttgc
    67201 tctttctctc ttttgcttct cttgggagta aaacacttgc tgttttcgtc aatggcagta
    67261 tcttgctgtt gattagcgcg cttattagcc ttctagtagt acacaggacg aatagaaaga
    67321 cagtgataag agtagatgaa gaaataaaag aacaattgac aacaaaataa atttgatgga
    67381 ggtcgtgtaa aatgacaaat gaaaaacata aagatagatg gctttggtat cctggagact
    67441 ttgagatccg ccatggactg ctacaaaatt tccaacggga agaacgaggt tttgactggc
    67501 cagcgtactg gtacatggat gattgccatc ggaacgtcaa gtttaagaga tattactttc
    67561 ttgatcaacc ttccatgttt aaagtgacga tccaaggagt tgggtatgta gaaattaatg
    67621 gacaaaaaca tccatgtgga aaatggctga cttgtccagc tggtaaagca aaaattcgta
    67681 tctttgtagg acatacatca gggctaccag cgatgtttat cgagggagac gaagtaaaat
    67741 cagatattgg ctggacagca agtaatttta ttgaagaata tccagctggc tggagtccgc
    67801 tttatgtcga tatcgcaaaa gatccaaatc aaatctatta tcaaaaagaa tgcgtccatc
    67861 cagtcactga aacggagatt ggcggaggaa tcttattcga ttttgggcga gcagtgaatg
    67921 gctgtgtaga actaatatct ctggatgacc atatcgaatc tatcactcta tgttatggag
    67981 agtccgatgt agaagctatg gatatcgatt attgctacta taagcaaata ggaatgacaa
    68041 gaaaaatgaa agctcgtaaa cgcgcttttc gctatttgtt tataccagag gtttctactg
    68101 gaatggttca acttcaagtt tttcatgaat ttttatctct ttcgaaacaa gctgcttttt
    68161 caagcgattc ttctttactg aatcagatct ggtcagtatc agaagaagcc ttcaagttat
    68221 gtagtgattt gttttttatc gacggtatca aacgagatcg ctggatttgg tctggagatg
    68281 cgtatcaatc attcatgatc aatcaatatc ttttttttga cgaggaaatc aataaacgaa
    68341 cgatattagc attaagagga caaaatgaaa tcaagcagca tatgaatact atcgttgact
    68401 attcgatctt gtggttgatt ggtatcgaaa accactatat gatgacgaaa gactatgaat
    68461 ttttacgcat cgtctaccct aagatgcaat cattaatgag atacttgatg gagcaaacga
    68521 atgaattagg gtttatttat gggagagcaa aagattggat atttattgat tggtctgaaa
    68581 tggataaaga aggaacgctt gctgcagaac aagtcttatt actgaaagcc tatcattcca
    68641 tgatcacttg cggagatatc ttagctgaaa catatggaga gaacgaaaat tatcatactc
    68701 atctctatca agaaaaatat caactattga aacaaaacct atttgactac ttttgggatg
    68761 aagaacttgg cgcttttatc gattgctatg aatctgggag aagaaatgtg acgcgtcatg
    68821 cgaatatttt cgctgtttta ttcgattttg ctaacaaaga ccaacagcaa tcgatcttaa
    68881 agaatgtctt attgaatgac actatcacac agattactac tccatatttc aaattctatg
    68941 aacaagatgc tttatgcaaa ctcggacaga cgaatatcgt ctaccaaacg attcttgatt
    69001 attggggagg gatgttatct catgatgcgg taactttctg ggaagaatac gaccctactc
    69061 aaacaggaaa tgaaaagtac agtatgtatg gagatcctta tggaaaaagc ttatgccatg
    69121 catggggagc aagcccaatc tatcttttag gacgctattt tatcggtttg tatccaacaa
    69181 agccaggtta tgaagaattt atgatacaac ctaatctaga ttcatttgaa acactgaatt
    69241 gtacgctacc tatcaaagat ggaaagattt cgcttgaaaa aacaaaagat aagatcgtga
    69301 ttacttctga tagaacaggc ggaacagtga aaatgaatgg taaaagttat cctcttctag
    69361 caaaacagcc acttgtctta acaagctatt caaaaataaa tgcataaaac aaaaaactgc
    69421 ttgcgacata tcagaagact ttaaatcttc ttctgatatt gtccaagcaa tttttatttt
    69481 gaagtttgct taattctgtt ctttagaaac aatgtttgtt ctttttccgg caaaaagaaa
    69541 gctagataat acgacaagta aaaagaaagc gatgattcca actgtcaagg ctatttgacc
    69601 gtattctcct agtttcccaa gtacaagtcc tggtactaga taatcagtat cggcaaatgt
    69661 agaagaagcg attttaagat ctcctaatac tggaaggata aataatggca gccaactaat
    69721 caataagcta ttgaaagcag aacctaatac cgcccctctt ctaccgccag tcgagttgcc
    69781 gaagacacca gaagcagctc cgcagaagaa atgtcctact accccaggaa tgataactgt
    69841 agtttgcaag cctatcatag caaacatgga tagtgttcct acaaagaagc taacaaaaaa
    69901 gccaattaat acagcattag gtgcatatgg aaaaacgata ggaacatcta atgctggttt
    69961 agaatcgggt acgagttttt tagcaatccc ttggaatgct ggaacgattt ctgccaacac
    70021 cattcgaacc ccttgaagga cgataacaaa cccagctgtg aatgttccag cttggatcag
    70081 tgcaaagatt acagcgttgt ctccattgct tagttctctt tcaacaaatc caggaccagc
    70141 taacaaagca agtgcgacat atacgatcga catcaagagc atgatcgata cagtagaatc
    70201 tcgcaaaaag ctgaaacttt taggaatctt tatgtcctct gtagaacggt ctttgtttcc
    70261 aaaaaacttt ccgatccatc cactagaagc ataaccgata tttccggtat gccctaacgc
    70321 aacttgattg tttccagtga tgttcttcat aaacggttga caaagagcag gcgtaatagt
    70381 taatagtgtt ccttcgaaga ccccgcctaa taagatcatc cacaaatttg cagtaaaccc
    70441 cgcgcttact aaaatgactg ctgttagaca agaaacataa agcattgctt gacctgtaag
    70501 aaaaatgaat ttatatcttg tgaatctagc aagtaaaata ttcacgatca tccctactag
    70561 catgatcaaa gcagtaggtg taccgtattg ttgcaaagca atcgccacta ctgcttcatt
    70621 gctaggaact actccttgag tatgcagagc tgtttggaac atcgaagcaa aaggggttag
    70681 tgaattactg attaaaccag caccgccgat cagtactagg aatccgacaa atgttttgat
    70741 agttccttgg atcacttctg aaaatttctt cttctgaaga acgagaccaa gcagtgcaat
    70801 caaagaaacg aggatggagg gctgactgac gattgacaca aacaaattca acaatttatc
    70861 cattgatagt tcctcccttg aatcattttt attcttttga caagatcttc gttacttttt
    70921 cttttacttc ttcgctgtca atgatcgatt gcaaaggtac gagcttttca tcaggtatag
    70981 aagttagcgt atctttcaaa gaatgctcaa tgaagaaata atcagccata tcgctagata
    71041 cacttccaac atccgtatga cttacttcaa actcgtccac atctgctcca agatctgcaa
    71101 gtgcttgttt gatgttcatc tctaccataa aacttgttcc taatccactt tgacatactg
    71161 caaaaatttt catatcattc gtctcctttt cttatgatcg ctaatatttc ttcttttgtt
    71221 gatgcgtgta ataaatcttg aagattttgt ttattagaaa gtagctttgt taaatttgcc
    71281 aaagcccgaa gatgtgcctc attatcgata gcagctaaac agatgaacaa actaatggga
    71341 tgggctggat tatcaagcag atccacaggt tgttgaagtt tcagcaaaga catccctact
    71401 tcgtttacgc catcttctgg acgagcatga ggtaatgcga tgtgatcgcc aatatggata
    71461 aacgcaccat actgctccac gcgctcgatc atagctttga tataactttc ttctatttta
    71521 ttttctgata atagcggctg tgcggcaaat gtgattgctt cttgccagtt ttttggttga
    71581 tccgataatt ggatcatttc ttctgttaat aattcagata gcataggacg ttgatcctcc
    71641 ttcttttcta aaagtttgtt cattttacga tttaatactt gatagagctt ttcttcgtct
    71701 acgccttctt ttaattcgat ataaggcagt agcgccgaca acaattcttg ggcagaaggc
    71761 attgaaaatc ctggtatcag ccaatctctt tgtacttgat tgatcagctg atttttttcc
    71821 aagtcagtca tgattggatg cagaacatag agagactttt tcttatcagt aagtgtgaga
    71881 ggtacagtag aaaaaataat atcgtaagaa gtttcgtcaa cctcgtgtaa gcggtcagct
    71941 gaattagtct ctgtaaaaaa gatcatcggg aataattgct gaagttcact ttttaagatc
    72001 aatgaagagc taatgccact tggacagacg atcacggctc ttatttttct atttctttct
    72061 tctgcgtccg cttttctgat ctctccgcca aatagtatag tgaaaaaacc aatctcttct
    72121 tcagggatgc tcttccctat tcgtctttct aacggaagta atgcttttct tgtcatttcg
    72181 tagatggaag catattgatg cttaatttga tcgatcatca cattaggtaa ataaaaagaa
    72241 taggaaatac gaaaataggc agggaccaag tgataaaaga cattcatcaa taattcacga
    72301 aacgaagcaa attctacggc catcaggaat tccatgcgat ggatgacttc tgaagaacat
    72361 tccagcaaaa aatcaagtgc aggctcctgg acatctcctt caacgatcga tgctaagcaa
    72421 agagagaaaa atataatctc cgaattttga tgttcggaat agccaaggcc agtcaatact
    72481 tgtcgactaa tgtcagtgac tgcaagagaa gccaacagtt cagcatcttt taccagttcc
    72541 atggatgttt ttccaattcg aatggttgtc aaactcaaat aataagctaa ttcatccatt
    72601 cgatttggtg cgaatcgaag atctgatagt gaaatcgttt tatctagcaa atctctaact
    72661 ttggcgtaat aatcaatgga aagggttgcg gttaaatacg tgagcccaaa tcttccagca
    72721 agtgactgca tcaaacgagc agtgcgattt tttgcttctc ttcttaatat tgcttctgac
    72781 cctagcagcc taaaaccagt tttcctagta tacgacagct gacaatcttc cacttctaat
    72841 tcatttctta tctttttgat atctgacagg actgtccctt tagaaacctg aagaaaatct
    72901 tgaaaatgaa aaacagaaac agacgttgca gtcgaataaa ccatcaaata aagaagatct
    72961 cttcgctctt gttcggtata cacagcttca aatcgagtaa tatccaaaaa tttttctgcc
    73021 cagtcgattg ctcggaattt ctttatacgg atacgggtat catccacata ttcggcaaaa
    73081 ggagttaatt gtttgatcgc ctcgcttgta tttacttcga tgatctctgc tgctttttct
    73141 agactgattt ctcttggtgt tttcaggaga taactaattt tgtagttcac agcgctgttc
    73201 acctcctact tatattctag tatggtagcg cttttaaatc gaggggtgtt tggtacaact
    73261 tacagttgga ttttttttac gactgtaccg aacgatttct atcgaatgga tacagaaaaa
    73321 aagcaggtga ccaaatgtct cctgctttta tgaattgatt tcgtccgatc aatgatgatc
    73381 atgtttattt tttgaggtca gttcttcaaa tttttctttg acatcttcaa ccgctttttc
    73441 gatatctttt tcaaagtgat tgggctcatt aggctttgtt tcctcttcta cagaatttga
    73501 accagataaa gctgtttctt tattttctgt ttcaccagag tttgtgccag ctaatgattc
    73561 ttctttgtct tctgtttcac cagaattagt tcctgctaaa gccacttctt cttctgtttt
    73621 aggggccatt gaacctctta atcgtttgtg tttttcaccg tcataatttg tcatgttggt
    73681 tcctcctagt agttctatac tttttcatcg tacaataaga cagtttatgc gtcaaaaaac
    73741 aaacccgatt cttacaaata tgtcatattt ttccttctga ttcttgaatg cttttgattc
    73801 cttcttccaa aattttcatt tgtaagattg tttcttcatc tttgatgact ttttctgcgc
    73861 cattaactaa tgtctcgtaa atcccttcgt agacacggct gtaatcacca acctcggaaa
    73921 ttactttttc ttcatgataa ctcccttgtt catctatata ggtcaataca ccataatgtt
    73981 cgggcaaatc gataccaaag tcttcatgat caggcatgta aaacattttc agatgttctt
    74041 cttgtcgatc ttttgtttgt ttcacgaaca tccctttttt tccgtaaacg acgaaacttg
    74101 gacgttcttt gatgcggaaa taactggatt ttatcgaaat tttcatattt ccatagaaaa
    74161 aatccagatc gaagtaatca ttcattcgtc ctttccctaa aagttgacgt acatcatagc
    74221 tgatatcatc tggttcgccg aaataagaaa gaacttgatc tactgtatga caagcatgtc
    74281 catataaata gctgttcgca gtagaaaatt catgcgtatt ttctggtact tccggtctga
    74341 aataatcata atgcatttct acttctaaaa tatcccctaa ttttccgctt tcgattactt
    74401 tttggactgt caagaagtca gaatcgaacc gtctgttttg gtaacattgg ataaatagac
    74461 ctttttcttt tgctaatgca aataactctt ctgcttcctt tgacgtttct gcaaaaggtt
    74521 tctctactag tacattctta ccatgttcga gtgccatttt tccatattca taatgaaatt
    74581 gactaggtgt agtgatgaca actaattgga tctcaggatc atcccaaaga tcagacagct
    74641 gatcagtata ttcgatgtct tcgaatgttt tccacactgg ttcagatggg gaaaaaattt
    74701 ttttgatatt gattttgttc gtaagttttc ttgaaaaagg caaatgatag cgatttgtac
    74761 tctttccatt gccaagataa gcgattgtaa gcatgagtgg tgcctccttt tattgatgtt
    74821 ttcagtatat cctagaaaag cgcagaaagt atttataata gctattctgg taaaaaagtt
    74881 cagaaaaaca cttgttatca ttcggtttgg tgaaattaat gttcaaagta aggataaaaa
    74941 tcaaaaagat agtagcggaa ccaagtgttt atcagtaaga tagaatttgg aggtcagatc
    75001 atgcttattg aagaaaaact aacaaaacaa gagttgttta ccacgacaga gaaacggatt
    75061 gtcgattaca tccgtaggaa tatcgaagct gcagtctaca tgacgattga agaattagca
    75121 aaagctacgt atacttccca ttcagctatc attcgtttat gcaaaaaaat gggattcagc
    75181 ggatttaaag aattccgttt cgagctgggg cgggaagttc atcaattgat tgctcagttc
    75241 aatcaaacga ttgatcctaa ttttcctttt tcaagtgaag atagcactca gcaaattgca
    75301 aagaaaatgg cggatttatc gatccagtca ataaaaaaag cacaattgca gattgaacat
    75361 gaagatttag atcaaatcgg taaagtattg aacaaggcac agcgaatctt tctttttgca
    75421 aaaggtgatt ctcaaatcac ggcaaggaaa ttccagaata aaatggtcaa gttgaataag
    75481 tttttgatca tggctgaaga atacagtgat tcttcttgga atgcagccaa tttgactagc
    75541 gaggattgcg ccatttttat tagctacagc ggtcgcatcc atcattatga acgaataatg
    75601 acctatttga agcatgtaga ggcccctacc ttgctgatta ccggaaatca gcattcagaa
    75661 atggccaaac aggctgatat gtgtcttgtt atatcgcagg aggaatatga ttttgctaaa
    75721 gtagcgactt tctcctctca aattgccttc gattacgtat taaatacgtt attctcagtg
    75781 atatattctc aaaattttga agagaatatc cgcaacttga aaaacaaaca agaattgatg
    75841 caaaaaggcc ttcttaaaga atatcggaaa acttaagaaa agatcctcat ttagtaataa
    75901 gaaagatagt gtttgatagg ctctctttga tatcatcata aaaacaggct gaagttttct
    75961 ttttcaaacc tcagcctgtt tgtttacgga acgattcgaa tagatatatt atagaaatga
    76021 ggaatagcta acttctgttt cttattttga acgattgacg aaaaagatat ataagaagga
    76081 ggaaaatcag tatacatgca gctaacaatc catacaggaa aaatcgtttg ttctcggata
    76141 ctttctgtac ttctttttga acttcttttg catgataagg aacccggtgc cctctgacaa
    76201 gtaagcgatg actgttgacc atataaggtg tacaagttag gagtgtcacg aaatcctgcc
    76261 ctttttcgat tctcagatct tttgtatcag tcggttctac cgtcttgatc tgatcgactt
    76321 gataagcgag tgtccgtcca ttgatttcga tatagaaaga atcacctaaa gtcagtttcg
    76381 gtaagtctgt gaacaacttt gcttgaggca gtcctcgatg gctggaaata acggcatgtg
    76441 tattttctcc ccccgtagga taagacgttc cttccaataa tgaggcacct ttttctagca
    76501 gcacagtatt cgtttcatca aaaattggca aatggacatt gatctcaggg atcgtcaaaa
    76561 taccgatcgt atgtttctca aaataggttc tatccttttt cgcaggttct tttttcttag
    76621 taaagggatc tgcacctgga tttccacctt cttttgctaa ttgctggttt ttctttgtca
    76681 tgttttcttg gattttagcc atgacttctt cattttcttt gaccgcttgt tgctgataat
    76741 gagagatgat ctgctgatcc agataattat tcagcgcgtc gctaacaaat ggataagcta
    76801 gtatccctat tcctgagaga agcaagaaaa gcatcagcag atctagaagt ttccttttct
    76861 ttggtttcat ttgtgttctc cttgtgatga ctgtttgata ataaaagaaa aaggagcatt
    76921 tgcgtaatcc gctgctcctt tttccaattc ttgcaaaaag actaaatctg actgtgcttg
    76981 cgtctagcaa agtacagtcc agcaatcagt agaaggacta ctcctgcacc gatatacaca
    77041 tagattccct taccgcctgt tgaaggaagt gtacctttgt gtttatttgg tattttttca
    77101 ggagaaatca actgtcctgc tgttacataa gattgttcat cgatagtaaa tgctacacgg
    77161 tttgttaatg gaacatattt ttctggcgct ttcgtttctt ccagatagta cgtgccatat
    77221 tttagacctg tcacatcgat taaaccgtta cttgtggttg taaaaaccgt tgctgattct
    77281 ttcgccgata cccagctgac ggcttttgtg gatgggtcga tcgataaata tttcgctgtg
    77341 tcactatctt gatcacgaac gacgaattct gctccagcaa gtgtttggtc tgatgtaacg
    77401 tcaccatcta ctttaacaaa tcgtttgccc ccagtaacga catcgactga cggtggtgtt
    77461 tgatcatttg tatgcccgtt atcgacattt gcttggttag aaaatccttt ggttggatct
    77521 gctttttcgt tcaaatgcat atagtaaacg aatttcaatg taccgccagg agttaatgaa
    77581 ggaatataat tcggatcaac tgaaaccgtg aatccgtctg tttgctcagt gacagaataa
    77641 tttactgggt cgatttcttt atttccatca tataaggcat aagcatacgt tcctgaagaa
    77701 tcattatcaa atgttaaagc agcgtcatga gtatcgataa gtttgaatgt tgtgtacttg
    77761 ttttgcgttc cttctttatc agcgatacct aatgggatat tgacagaaat ctcatattga
    77821 attttttcac cgattgcgac atcttttcca ttcaattgag gtgttgtttt atcaacttta
    77881 gacgtatcat ttttgatggt cttttctact ggtgtttggc tatttgccag gatctcaaaa
    77941 ggcgtgattg tttgcttttc aatcatttcc gcattatcag gagcttttac ttcttctaaa
    78001 ttatattttc caacttctaa atgattaacg atcaactggc ctttttcaat agatgcctcg
    78061 gcaaagtcat tgttgccgat gtcataagaa tgaccagtaa tgaaatgttt ggctttggtt
    78121 tgatcagttg tccaagtgta caatccatct gtgacacttt ggatgtattt tttgacgctt
    78181 ggtgttcctt cttctttaga aataataaat tctgctccat ttagtgcttc gttttcggca
    78241 gtaccgattt ttgtaacttt caacgttcca tcattaccga ctgtattttt agggtagaga
    78301 tggatagtat ctagttcttc tgtcccgtat ttataagagc catctgcttg tttgatcatc
    78361 tcatatacag ggaaagctaa aaccatgttt gcggcagctg acactccgtc ttttggttct
    78421 tctttgatcg tgtagactgc atctttccca ttttgttttt taggtaaaga taaagtgaca
    78481 tttccatcag catctgtcgt tcctgaagca actggtgtac caggagtcaa agactggact
    78541 gcttgttttg ctgcatccac ggacgctcct ttatctcgtt gcgcataaaa ttcttgagtg
    78601 acgttataaa ctgaaaatga aatatcggct aatccttggt attgatcgaa ttcgctcatt
    78661 tctttcccgc tgttttggat taaaggatcg ggtaaatcag tcattttctt tttatgaagg
    78721 atgacttgag ctgctgtctc ctctgcaaac actttttttg cgccgaagct gtttgtgagt
    78781 aatggtaaaa taaggaaaag gactcctaac ataacgttta tttttttatg atttttcatt
    78841 ttttcactcc tgttcttttt ttgataaaca accagattgc aaagcttgcg aataccatac
    78901 caacaacgcc taaaagtgta tttttcgttt cgtttgtttt tggaagaaat ggacggctat
    78961 tttctttttt attgactact ttcaatatac tgtccgcctc tttatcctca gaaagaaaag
    79021 ttgaaatggt aaacggaatt tctgtttcac ttaaaatata accagaaggt gcttcgatct
    79081 cttttaatcg ataacttcct gttttcaacc cggaaattga aaaagcgcca tttttatcgg
    79141 aaatcaggtg aagcgcatct gattcgttct ttgtccactt gtatccgttg gctgtttgct
    79201 ggaggtaatt tcctgctttg tttttaataa ggaatactgc gccagctaat cgtttatctg
    79261 gtttatttgt ctcgattttg acaaattgct tactccctgt atatacagag actttctttg
    79321 tactgacacc aaaaccaaaa tccagtgttc cgttgttgtt gatttccttg ttcgcctgtg
    79381 ctgtactgct tagctgcatc tgataagaaa tggtcagttt ttttccagca tatttttcca
    79441 acgaagggat cgaaaataaa acatcaaatc cgtgaggttt cttgtgtatg acaaagcctt
    79501 ctgtcagctt ttctccattc gatgaaatcg ttaaactatt aggtaaaaac gttaatgctt
    79561 catccgcact atctgacaat tcgaactttt gatagtcaag gatatttaca ggaattgtcg
    79621 tatgcaagga ataagtgatt ttttcaccaa tcgtaaaatc atttctaggc tcttctaata
    79681 ccttctcaaa aggtggatca gggtagtcgt tttcttcatt tttaggatac aaatggatag
    79741 ttgaaagttt ttgattgttt tgtccatgta caggaagaac aactaccata ttctctgcct
    79801 tttctttgac gacttctggt actttggatt caatgaaaag atacgcttta tctctttttt
    79861 cttgatcttt agcggccaga gaaaaagaag cgataccatc ttcgttgtta agagttgtag
    79921 ttgttgcttc tgcggtaaac ataccggaag acgcaccgtt ttttgcgatc tctgcttgtg
    79981 cttcttctac cgttttgccc ttttcccgta gatggtaaaa agaatctgtg acatcataaa
    80041 cttggaatgt gacaccattt aatcctcgat acgtttgtaa taaagctttt tcttgtccgt
    80101 catttggatg atttttcggc agttgcccgt ttgggaaaag caatttgtgt aaagtaatct
    80161 gaaccatttc tgtttctgtt tctgttgcta cctgagtaaa agctggttta aatagtaaca
    80221 agaagagaca catactaagc caaccaagtt ttttcatatt tagctgcccc ctctttcttt
    80281 tttcaaaaaa agataccaaa tagaaaacgc acaaccaatc atccctacta gatagattcc
    80341 taaacggcca attcctcccg tttcaggtaa tggtactttt gcctgattcg tgatgtctaa
    80401 agaaatctgg ttgtttttgg ctcctggtga cagaacagat tcatgatctt gtccatccac
    80461 ttgaattgac ccatcttcgt gtataactat agtaactggc tcttttagac cttggtatcc
    80521 ttctggtgta aaagtttcgg tcagcgtata agttccaggt tttaaatttt cgaatagaaa
    80581 ggtatctgtt tcttgtccat cttttggcga ttctaagtcc atttctggtc cctgcagtct
    80641 gaattttgct ccttttaatg tctgtccgtt gtcttctttt ttgtgtaccg ttagatcaaa
    80701 cgcttttagt cgattttgat gagtgagcgt ccatacatta tttgtcatct cggtattttt
    80761 tcccgtgtaa atgatttttc catatttatc gatttggaat tcataatttc ccggcgaagt
    80821 atcatatccg gcaggaccag ctgtttcaac gactcgatat ttaccaggtg tgagtgaatc
    80881 aaaactggca agaccttttt cattcgttgt ttggctgtca attggctgat aagtaccatt
    80941 tgcttctttt ttctgtaggg aaaatgctgc tcctttaaga tttatctctt tgtccgtccc
    81001 ttgcatcgca tacttacgta ctgctacagg aacttcaaca aaaggatttt caatagtcaa
    81061 ctggatcgta tcatcggaag tagtgactgt ttttccatca atggttaccg taccatcaga
    81121 agcgatcttg atttcccaag tagtcttttt gcttaatcca tgcccttctg gagcttttgt
    81181 ttctgtcagc gtataggtca tttctttttg caatttgaca ttttctggaa gagaataggt
    81241 tccgtcgcca tgatctgtta gtaaagtatc aatagaatct cctgttaatt tgaaaacagc
    81301 gccaataaga tccttttcac ctgtagagga atttttcgtt attttcaagt ttaacggtgt
    81361 gaattgttta gtatttttcc atgtcattgc atctatttgt tgagaatcgt atcctggtac
    81421 aggtaattct ttgattgttt ggtaactgaa tgcttgacct tgattattgt attgaggtag
    81481 tgataatatc tcttgataac tttctccgct atttgcagat aatttgtcaa tgtctgcacg
    81541 ttcccacgta tttgttgtat ctttagctgg tttaatgatt cgaatatatc cgtttttcca
    81601 agctgcagca tttgtcgtat gttcccgttg aatctcaaaa gtaacttgat ctggacgatc
    81661 agctagattg ttgtcaaatt cttcccataa ctttttgatg tgaagactga ctccgggagc
    81721 tttagcagat ggtataccga attcagctaa ttcattggta tcaatgtttg gctggaaagt
    81781 tgtcctgccg ttcatttgat accagaaatt tggatggaag tcctcatttt ctgtttggat
    81841 tctcacttgg taatggattt ggatttcttg gtcttttcct aaatagatct gattgctctt
    81901 gatggtattt ccttctatgg aaatagatgg agtgaccgtt gtaggacttg tccccacact
    81961 cttgactgaa agtgtaccag gctgataaat gaatggttct gcgattggat catttatttg
    82021 tccattgctt acagttgctg agatctgtac agcttttttg gctaggtatt cagagatatc
    82081 tgttgcatga tcagctgatt catagtaaag atcgcctttt tcatctgatg aaaccatttg
    82141 tcgcatacga gactctactt ctgcttttga gagaccagct gccggatcgc tttgaagttg
    82201 gatgccaaga ccatgtattt cgattcctcg ttctttgagt gccatcgctt ctccgatggt
    82261 tgcgataaac gtactgtcga ttcttctgga tagattgttt tggtcaggtg catcatagat
    82321 tcttgagatt agagaagtat ttcccggccg atcttgcgta ttagaaaact gagttccgta
    82381 ataattgctg cttgattgtg cgtgtacccg ctgtacttta taggaaaatg ttggtacacc
    82441 atccgtcagc aaaacgatca cttttttatg tccatttgga acggatagca tgcttcctgc
    82501 atctcttagt gctttttgtg taaaagtacc accatttgtc cgtgaaggtg taatggattt
    82561 tacttgattt ttcactgaat caaatgaacc catctgtact gcaccgttac tgtagctata
    82621 tccttcgctt gagtagccga catatcccat attgattttg tctgtgatac cgctatctgc
    82681 taaagtatcg acaaaacgat cgacaccaat ctttacttca ccgatccgat tattgtcgtt
    82741 catacttcct gaccagtcta cgaccaatac gagatcaaga ggcgtgatat ctttttgtac
    82801 atttccacga gcattcaaat aaacatcaaa caatccgggt gtacttgttt cctttgcata
    82861 ctttcgtatc gcatagtctg cttgattacc ggttcctcca tattcgatat acgaatgggt
    82921 ccgatcatta ggatctccat tccaagaatt tataccatcc cattgatttg ttccgttttt
    82981 attgccttga tgatcaagaa catttgtatt tcctgtaggt tgccaactgg ctttaggata
    83041 agtgccctga tcatctgttg tatattctgt aggaatcgtt tgattagatg gcacactcac
    83101 agctggcaag gataatgtag gcaatgtaaa tgggctgaca gaattttcgt tttcttttga
    83161 tgattcttct tctatttcgt ctggctttgg tactgacaca tctgtatctt tcttattttc
    83221 tgtctcatca ataatgtcat attctttatt atcgacgatc agcttgtttg cctggctgtg
    83281 gtaaagtgct ggatcgattg gaaaactcag atcgatagtt tgtttagtgt ttgatgagat
    83341 ttccaacgta attttcccgc tatttacctg ataagcatag ccatctcctt cttttctttc
    83401 cacatcactt aagtaatttt cgactagacc aatttctttt tctatctttt cagcactggt
    83461 gttattcgca tttagcttga tgttcagtgc tttttttcca gactgatccg aaatgacttc
    83521 agctgaaatt gtttctaaaa ctgttggatc atctgtagtg tctgctattg cagataatgg
    83581 cacaaagttt gataaactca atattatcag catgaaaata actttcagtt tcttccctgt
    83641 ggtcgtcatt tttcccctcc tttttctttt tttctgtttt gacgtgaata gtgaaaatta
    83701 ttaaaataa
//
LOCUS       DAFEML010000006        69096 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFEML010000006
VERSION     DAFEML010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.006"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(23..391)
                     /locus_tag="LP468_000498"
     CDS             complement(23..391)
                     /locus_tag="LP468_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBL2080061.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="LP468_000499"
     CDS             complement(1002..2393)
                     /locus_tag="LP468_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL2080062.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="LP468_000500"
     CDS             complement(2606..2992)
                     /locus_tag="LP468_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL2080063.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="LP468_000501"
     CDS             complement(3048..3671)
                     /locus_tag="LP468_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL2080064.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="LP468_000502"
     CDS             complement(3735..4403)
                     /locus_tag="LP468_000502"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2080065.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="LP468_000503"
     CDS             complement(4415..4855)
                     /locus_tag="LP468_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080066.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="LP468_000504"
     CDS             complement(4914..5585)
                     /locus_tag="LP468_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2080067.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5770..6168)
                     /locus_tag="LP468_000505"
     CDS             complement(5770..6168)
                     /locus_tag="LP468_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL2080068.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="LP468_000506"
     CDS             complement(6165..6938)
                     /locus_tag="LP468_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2080069.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="LP468_000507"
     CDS             complement(6935..7618)
                     /locus_tag="LP468_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2080070.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="LP468_000508"
     CDS             complement(7785..8672)
                     /locus_tag="LP468_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080071.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="LP468_000509"
     CDS             complement(8669..9538)
                     /locus_tag="LP468_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080072.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="LP468_000510"
     CDS             complement(9675..10961)
                     /locus_tag="LP468_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2080073.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="LP468_000511"
     CDS             11234..11812
                     /locus_tag="LP468_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2080074.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="LP468_000512"
     CDS             11812..12741
                     /locus_tag="LP468_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2080075.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="LP468_000513"
     CDS             12738..14474
                     /locus_tag="LP468_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2080076.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LP468_000514"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LP468_000514"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL2080077.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="LP468_000515"
     CDS             complement(15370..15879)
                     /locus_tag="LP468_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL2080078.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LP468_000516"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LP468_000516"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL2080079.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="LP468_000517"
     CDS             complement(17180..18271)
                     /locus_tag="LP468_000517"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL2080080.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LP468_000518"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LP468_000518"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL2080081.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LP468_000519"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LP468_000519"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL2080082.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LP468_000520"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LP468_000520"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL2080083.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="LP468_000521"
     CDS             complement(22234..23208)
                     /locus_tag="LP468_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL2080084.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="LP468_000522"
     CDS             complement(23189..25072)
                     /locus_tag="LP468_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL2080085.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="LP468_000523"
     CDS             complement(25090..27315)
                     /locus_tag="LP468_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2080086.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="LP468_000524"
     CDS             27430..28464
                     /locus_tag="LP468_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080087.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29544)
                     /locus_tag="LP468_000525"
     CDS             complement(28531..29544)
                     /locus_tag="LP468_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2080088.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29622..29810)
                     /locus_tag="LP468_000526"
     CDS             complement(29622..29810)
                     /locus_tag="LP468_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL2080089.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30250..30378)
                     /locus_tag="LP468_000527"
     CDS             complement(30250..30378)
                     /locus_tag="LP468_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2080090.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="LP468_000528"
     CDS             complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="LP468_000528"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2080091.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31865..32920)
                     /locus_tag="LP468_000529"
     CDS             complement(31865..32920)
                     /locus_tag="LP468_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2080092.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="LP468_000530"
     CDS             complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="LP468_000530"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL2080093.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="LP468_000531"
     CDS             complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="LP468_000531"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL2080094.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="LP468_000532"
     CDS             complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="LP468_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL2080095.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="LP468_000533"
     CDS             complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="LP468_000533"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL2080096.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="LP468_000534"
     CDS             complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="LP468_000534"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL2080097.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40682..42241
                     /locus_tag="LP468_000535"
     CDS             40682..42241
                     /locus_tag="LP468_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL2080098.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42352..44283)
                     /locus_tag="LP468_000536"
     CDS             complement(42352..44283)
                     /locus_tag="LP468_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2080099.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="LP468_000537"
     CDS             complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="LP468_000537"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL2080100.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45212..45964)
                     /locus_tag="LP468_000538"
     CDS             complement(45212..45964)
                     /locus_tag="LP468_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2080101.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46124..46333)
                     /locus_tag="LP468_000539"
     CDS             complement(46124..46333)
                     /locus_tag="LP468_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080102.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46344..47672)
                     /locus_tag="LP468_000540"
     CDS             complement(46344..47672)
                     /locus_tag="LP468_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080103.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47808..47963
                     /locus_tag="LP468_000541"
     CDS             47808..47963
                     /locus_tag="LP468_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080104.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(48037..48624)
                     /locus_tag="LP468_000542"
     CDS             complement(48037..48624)
                     /locus_tag="LP468_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL2080105.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48707..49957)
                     /gene="clpX"
                     /locus_tag="LP468_000543"
     CDS             complement(48707..49957)
                     /gene="clpX"
                     /locus_tag="LP468_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL2080106.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50204..51493)
                     /locus_tag="LP468_000544"
     CDS             complement(50204..51493)
                     /locus_tag="LP468_000544"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL2080107.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51647..52579)
                     /locus_tag="LP468_000545"
     CDS             complement(51647..52579)
                     /locus_tag="LP468_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080108.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52736..53395)
                     /locus_tag="LP468_000546"
     CDS             complement(52736..53395)
                     /locus_tag="LP468_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2080109.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53398..54423)
                     /gene="sppA"
                     /locus_tag="LP468_000547"
     CDS             complement(53398..54423)
                     /gene="sppA"
                     /locus_tag="LP468_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL2080110.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54436..54726)
                     /locus_tag="LP468_000548"
     CDS             complement(54436..54726)
                     /locus_tag="LP468_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080111.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55135..56940
                     /gene="glmS"
                     /locus_tag="LP468_000549"
     CDS             55135..56940
                     /gene="glmS"
                     /locus_tag="LP468_000549"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL2080112.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57012..58367)
                     /locus_tag="LP468_000550"
     CDS             complement(57012..58367)
                     /locus_tag="LP468_000550"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL2080113.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58391..59560)
                     /locus_tag="LP468_000551"
     CDS             complement(58391..59560)
                     /locus_tag="LP468_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080114.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59557..60444)
                     /locus_tag="LP468_000552"
     CDS             complement(59557..60444)
                     /locus_tag="LP468_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL2080115.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60633..64325)
                     /gene="nifJ"
                     /locus_tag="LP468_000553"
     CDS             complement(60633..64325)
                     /gene="nifJ"
                     /locus_tag="LP468_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL2080116.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGVSPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64524..65045
                     /locus_tag="LP468_000554"
     CDS             64524..65045
                     /locus_tag="LP468_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2080117.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65744..66301)
                     /locus_tag="LP468_000555"
     CDS             complement(65744..66301)
                     /locus_tag="LP468_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080118.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66480..67091)
                     /locus_tag="LP468_000556"
     CDS             complement(66480..67091)
                     /locus_tag="LP468_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080119.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(67204..67461)
                     /locus_tag="LP468_000557"
     CDS             complement(67204..67461)
                     /locus_tag="LP468_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080120.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(68058..68336)
                     /locus_tag="LP468_000558"
     CDS             complement(68058..68336)
                     /locus_tag="LP468_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080121.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(68370..68621)
                     /locus_tag="LP468_000559"
     CDS             complement(68370..68621)
                     /locus_tag="LP468_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080122.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19332 a        14926 c        12142 g        22696 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cacttttaaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg ctgcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat tttcttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct ttttttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag ctgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    29341 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    29401 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    29461 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    29521 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    29581 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    29641 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    29701 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    29761 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    29821 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    29881 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    29941 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    30001 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    30061 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    30121 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    30181 tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct
    30241 ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac gatcattctt
    30301 aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat
    30361 tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga
    30421 tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca
    30481 aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct
    30541 ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca
    30601 actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct
    30661 tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct
    30721 tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac
    30781 aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg
    30841 gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat
    30901 gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca
    30961 tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg
    31021 atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta
    31081 aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga
    31141 cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg
    31201 aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg atcttggata
    31261 taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac
    31321 tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc
    31381 attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc
    31441 tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg
    31501 atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata
    31561 aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag tatttctact
    31621 tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc
    31681 attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt
    31741 tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta
    31801 taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt
    31861 ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt
    31921 catccgttaa acgttcgact tcttttacga attctttgct gacaacctct aattcttctt
    31981 catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt
    32041 gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga
    32101 tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat
    32161 agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca
    32221 agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt
    32281 tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca
    32341 tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta
    32401 ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta
    32461 gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga
    32521 agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt
    32581 ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg
    32641 taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca
    32701 cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga
    32761 ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt
    32821 caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc aataattctt
    32881 ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg
    32941 ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt
    33001 tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga
    33061 cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag
    33121 ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca
    33181 attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa
    33241 tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt
    33301 tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat
    33361 tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt
    33421 catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag
    33481 gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag
    33541 gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat
    33601 tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt
    33661 ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt
    33721 ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg
    33781 catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta aattggataa
    33841 ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag
    33901 aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa
    33961 taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt
    34021 tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt
    34081 gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag
    34141 tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag
    34201 ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt
    34261 ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact
    34321 cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat
    34381 agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat
    34441 cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa
    34501 acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc
    34561 actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg
    34621 tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat
    34681 caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga
    34741 gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt
    34801 gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc
    34861 gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc
    34921 gtattttgaa tgaggcaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc
    34981 tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt
    35041 aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac
    35101 tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa
    35161 tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc
    35221 aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa
    35281 agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc
    35341 agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca
    35401 agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc
    35461 catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc
    35521 atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt
    35581 tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat
    35641 ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa
    35701 tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg
    35761 tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa
    35821 ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg
    35881 tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga
    35941 tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta
    36001 tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt
    36061 gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct
    36121 tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt
    36181 aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt
    36241 cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact
    36301 tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg
    36361 atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct
    36421 tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta
    36481 aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg
    36541 cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact
    36601 acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt
    36661 ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg
    36721 acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg
    36781 attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct
    36841 tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt
    36901 tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc
    36961 aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca
    37021 tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg
    37081 ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct
    37141 ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta
    37201 tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt
    37261 ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact
    37321 tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt
    37381 tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa
    37441 tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat
    37501 agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac
    37561 tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt
    37621 cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga
    37681 ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt
    37741 tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg
    37801 accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga
    37861 gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt
    37921 tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa
    37981 gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg
    38041 actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg
    38101 atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca
    38161 tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt
    38221 gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt
    38281 taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc
    38341 ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac
    38401 tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc
    38461 ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc
    38521 tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag
    38581 taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata
    38641 taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac
    38701 atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg
    38761 aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc
    38821 atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac
    38881 aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc
    38941 attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt
    39001 ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct
    39061 acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac
    39121 ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc
    39181 cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg
    39241 tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa
    39301 actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc
    39361 tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag
    39421 agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta
    39481 attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc
    39541 tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa
    39601 gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt
    39661 tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc
    39721 aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc
    39781 tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc
    39841 gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt
    39901 gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc
    39961 catacattga ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc
    40021 ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc
    40081 ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc
    40141 ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg
    40201 gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt
    40261 cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc
    40321 ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc
    40381 ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc
    40441 cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc
    40501 gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa
    40561 ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta
    40621 tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg
    40681 aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa
    40741 aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga
    40801 aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt
    40861 aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa
    40921 tgaaccggat atcaagggaa gcgggattcc acaagtagag ggacagcttc gcggggaatt
    40981 atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg
    41041 tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca
    41101 aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg
    41161 tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt
    41221 agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat
    41281 cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga
    41341 ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg
    41401 catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt
    41461 gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta
    41521 tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc
    41581 cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc
    41641 ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat
    41701 cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga
    41761 ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc
    41821 aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc
    41881 tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt
    41941 attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt
    42001 tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg
    42061 gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg
    42121 tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc
    42181 aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta
    42241 acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga
    42301 ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt tctatgcttc
    42361 tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga ctgctccgat
    42421 agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga aaatcccgcc
    42481 gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta aagcagaacc
    42541 aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa tcgatccttc
    42601 cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat ctgttttgct
    42661 gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta ccattcctcc
    42721 agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag ctaaagttgc
    42781 tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg ccatcattcc
    42841 agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca agaaaccgtt
    42901 caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga aaccagtaat
    42961 cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg attttggtaa
    43021 gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc caccaatcag
    43081 tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa atccaacgat
    43141 caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg gcagcatgaa
    43201 accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt aattccctag
    43261 atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag aaagcgcaat
    43321 agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca tcaaatcttt
    43381 gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc tttcttttcc
    43441 atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact cttctggttt
    43501 acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc gattcatctc
    43561 tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt cagcagtcaa
    43621 tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac ccatttcttt
    43681 cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg ttggacaagc
    43741 tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag cttgtgtttc
    43801 ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca agtcttggac
    43861 ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa tcagcaatcg
    43921 agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag ctgcgatcat
    43981 gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt tttggctttt
    44041 tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca tggcgattcc
    44101 atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt tatatgtttc
    44161 gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga ttgcgccttt
    44221 tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat ccttgatatt
    44281 catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg cagcaactca
    44341 tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc gcaagcaact
    44401 ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat aaagccagca
    44461 atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac attcgtttta
    44521 taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat cagcacattc
    44581 tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac agattggaag
    44641 gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa cggtttctta
    44701 acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc acctttttct
    44761 cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg cgcgcttcct
    44821 gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa ctcatcgatt
    44881 tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtgtc tgattttagt
    44941 ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat ttgttctttt
    45001 tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag tgctgtagat
    45061 tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc aggtaacttg
    45121 aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg tacgatataa
    45181 tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta attgttgtct
    45241 tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc gtggctgctt
    45301 ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca atcaatacaa
    45361 atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct ggatccggag
    45421 tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta ttaaaatgaa
    45481 aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc agctttatcg
    45541 ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca tgttgaacgg
    45601 aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct aacgtagtag
    45661 agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc gatttggcga
    45721 tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc tcaaaattca
    45781 ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta ttctccagct
    45841 cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca agatcttgtg
    45901 atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt tcctctgtaa
    45961 gcattttcac gatcacctca atacaaataa tagcatattt tttttctact agcaatataa
    46021 atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaaataa aaaaccagtc
    46081 agaaagactg gttttttatt tttttgtcta tcatcaagcc gttttatcgt tttttatttt
    46141 cgcttcttgt ttttttcata taaacagaag caggttttct ttccttatga agaagataat
    46201 aataaagtcc catcccgcca aacatgacca aaaaaccgat gactgatcga ataggaaaat
    46261 taggaacaaa aaagagacag acggataata atgatgccgg aaccattatt cgataataga
    46321 gttgtttatc cattttcttc acctcatatt ttttgtaaag taatcaattg ttctaattct
    46381 cggtaatcta aaaattgcac acgcagatgc tgctcacctt tcttgacatc gaattggata
    46441 cttcgccgct ttttctttat tcgtttgaag gtaacatcag agagtctatg tttgatttcc
    46501 tttaacggta attctgacag ggattctgaa ggaacataga ttcttaagga taaaagatac
    46561 tcttgatatt tttcatctgt tacctctact tctagatatt ccctaatata ataacaataa
    46621 gcttcgattc cattatccaa agcaacagtc ggatcgataa ctttatagca catcatgcgt
    46681 gatcgattct cgtcaaccca aggaaaatac gcctgagcat ttagtgttcc gcgaacacgc
    46741 ctttctttat aatctccttg ttggatatca taactttttg ttacaaaaaa tgaagcattc
    46801 tttttaggaa caggttgcat ttgtgcattc tgatactgga cagattggat cgtatggtca
    46861 gtgtaaatgt attcaacgaa tggcggtttc aataaaccga caccattgtc ccaagcaaga
    46921 tgatcaaacc caagctggtc cctaaaatag gattgaaaca tttgattgtt tggcttttgc
    46981 cagttaaagg ggtctcgata aagctggata catatgactt cgttttctaa ttccttcact
    47041 ttttctactt gttggatgtc gagaaaaatc ggtttaggga tgatttgatg ataatagcga
    47101 ctataataca tttcccaaca cgaagtgaaa cataaacctt ggtaaaaaag atcgtatcct
    47161 ggaaattggt tgcaatcgac tactacttcc ccgttttgtt gtttcatttt aggtaaatgt
    47221 tcgatttcat cctttttctc aaacaatagc cgttgagaga tctgttttgt attgtgatag
    47281 ataaactcgc tataagctcg catataggcg aacaccccat gagcaatcat ttttttctga
    47341 atgaagtctc gaatcaaaaa ttgcttttct ttgaaaacag agatagacaa tacatttttt
    47401 atcaataatt gattatcttc caagcgaaaa ctacattcgt tctcgtcatt tcctacaact
    47461 aaccaacttt cgtctcttac cgatgctagc attatttttt cttgaagctt tcgaagatca
    47521 tacggatccg cttgttgtgt gaaagagcgg ataaatgttg gctggatcaa cagacgtgtc
    47581 aaaatagccc aatcgcttat ttcctgtttt ttttcttctt catttaagtc tgtgagctgg
    47641 atagtcatca ataatttatc ttcgccaatc attttctcac ctctttcaaa tctttttata
    47701 atttaattat aaccaatgat aaagaaaaac taaaacttta tgtcttagaa accaatttgg
    47761 acgattacat gatagactaa gtaaaaagaa acaaagaggt gtttacaatg gggttgaaat
    47821 ttgaacgtac agataattta gataaacttt tcgaatcatt tgctgtcgat ccggaaaaaa
    47881 cagttgcacc aaaagaagag atcgatcgat ttctaaaacc acagccacaa aatgaaaaga
    47941 aaaaagacaa gaaacaaaag taagttaagc tcaaaaaaag acttaccagc caaactttta
    48001 tgaaagagtt tgactggtaa gtctttttta ttctttttat gattcaattg cttgttcgat
    48061 tgctgcccac gcttcttctt ttccctgttt tgtaacggaa gaaaagagaa taaacgtgtc
    48121 attgcgatca aaatccaacg cttttttgat ttcgctctca tgcttgttcc atttaccacg
    48181 agggatctta tctgccttag tggcaacaac aattacaggg atatcataat acttcaaaaa
    48241 ttgatacatc tggatatctt cttgagaagg cttatgacgc aaatctacta aagaaacgac
    48301 cgcacgtagc tggtctctag tcgttaaata tgtctcgatc atctttcccc attttgctcg
    48361 ctcagttttg gatacttttg catacccata tcccggaaca tcgacaaaat gtaatgcgtt
    48421 ctcgatcaaa taaaaattca atgtctgggt ctttcctggc ttaccggaag tacgggctaa
    48481 attctttcga tcaatcaatg tgttgataaa agaagatttc cctacatttg atcgtcctgc
    48541 cagagctatt tctggcaatt gtgtatctgg atattgtttt ggtgccactg cacttatgat
    48601 aatttcagct tgatggactt tcatggtctc tctccttaac aaggtgatga ataaagcaag
    48661 cggctgtcgc aaaagccaaa atgactttta cggcagcctc ttttcatcaa cccgcttttt
    48721 tctctgaatc tttatagatt actgttggct caccagacaa ttcagctgct tcttttgtga
    48781 taatcacttt ttcgatgttt tcatttgaag ggatatcaaa catcacatcc atcatgattt
    48841 cttcaatgat ggaacgaagt cctcgagcac cggtattgcg ttcgattgct tttttcgcaa
    48901 tggctctcaa cgcttcaggt tcgaattcaa gttcggtatt atctagagaa agaagttttt
    48961 gatattgttt gactagcgca tttttcggct cagtcaagat ccgtaccaga tcatctgttg
    49021 tcaatttctc taaagctgcc ataacaggta atcgtccgat aaactcaggg atcaatccga
    49081 attttagtaa atcttcagga atgatatgct gcatgacact ttcgtcttca gaaagttttt
    49141 ggttttgtgt accaaatcca atcgtctttt cgcccatacg attcttcaca atcgtttcga
    49201 tgccatcaaa tgcaccacct acgatgaaca atatgttcgt cgtatcaatc tgaataaatt
    49261 cttgatgtgg atgtttacgt ccgccctgag gtggcacact tgcaacagtt ccttctagaa
    49321 ttttcagcaa ggcttgttgg acaccttcgc cggaaacgtc acgagtaata gatacatttt
    49381 cgcttttacg cgcaatttta tcgatctcat caatatagat gatccctttt tctgcaagtt
    49441 ccacattgta atcagcagat tgaagcaatt taagcaaaat gttttctaca tcttccccca
    49501 cataaccagc ttctgtcaaa cttgtcgcat ctgcgattgc aaaaggtaca ttcaatgttt
    49561 ttgctaatgt ttgtgctaaa aatgttttac cagaccctgt aggtccgatc aagcagatat
    49621 tgcttttttg cagttcaaca tcatctgtgt tttcttgtgc ttgctgattg acacgtttat
    49681 agtgattgta tacggcaaca gctaacgagc gttttgcgcg atcttgtcca atcacgtagt
    49741 tattcaatac ttcaagaatt tctagtggtt tagggacttc agtgaattcg cgtacagctt
    49801 cttcataaaa ttcttcatca atgatttctt tacataggtc gatacattca ttacagatgt
    49861 agacccctgg accagctacg atctttttca cttcttcttg ggttttcccg caaaaagaac
    49921 agcgtacggt ctcattgcta cttggattgt catacatggt cttcacccct taacttgcaa
    49981 aaagtatgca agaaactatc aaagacttta cagtctttta ctatcataac atagtttagt
    50041 aaaaagaaaa agtgtttaac aaaggatcaa ctgacctata cctttgcatt ttttactctt
    50101 aacaaaaaat aaggaactgt gacaaaatcg tgtcacagtc ccttatttcg aataaacaat
    50161 tttctagaag tagcttcttc agaaatgatt tattacttga tttctattct ttcgcttctg
    50221 tcgctgtacc tgtgatcaat tcgattgctt ttttcattgt cacatcatgt tccagcatat
    50281 cttctgtcaa cacgcgtttg atttgttcga ttggcatgtt gtatgtttct gataattctt
    50341 ggatttctgc attgatttct tcttctgttg cttgaagatt ttcagcagct gcaattgctt
    50401 cgatcacaag atttgttctt gtgcgcattt ctgcttcacc ttcgaattgt ttatgcaagt
    50461 cttcttctgt agaaccagtt aattgatagt acatttcagg agagatacct tgacgttgca
    50521 tgttgttcaa gaattcgtcc attgaacgat gtacttcatc atgaaccatc acgtgtggca
    50581 attcaacgat ttctgcgttt tcaacagcca tacggatcgc tgcttcatct tttgcatcgt
    50641 ccgctgcttt ttcttttgtt tctactaatt ctttgcgata tttttctttc aattcgtcta
    50701 atgttgatac ttcgtcatca acatcttttg cgaattcgtc atctaattca ggcacttctt
    50761 ttgcttttac ttcatggatt gtcactttga agactgcttc ttttccagca agatcttctg
    50821 cttgataatc ttctgggaaa gttacattta catctagact ttcacctgat ttatgaccaa
    50881 ctaattgatc ttcaaaacct ggaatgaatg agcctgaacc taattcaagt gagtaatttt
    50941 cgccttttcc gccatcaaac gcttcgccat ctacaaagcc ttcgaagtcg attactactg
    51001 tatcgccatt ttcagctgca gcatcttctt tgataactaa ttcagcttgt gcttcttgtt
    51061 cacgtttgat acgtgcatcc acgtcagcat ctgttacttc acggtcttgt ttttcaacaa
    51121 ctagatcttt atattgtcct aattttactt ctggtttcac tgttacttca gcagtgatta
    51181 cccagtcttg acctttttcc atgctttcaa catcgatttt tggttgagaa acaggatcga
    51241 tgccagcttc tttgacagca gcttcataag cttctggtaa tacagcattc aatgcatctt
    51301 catataaagc ttcttcaccg tacatacggt tgaatacttg acgagaaact ttccctttac
    51361 ggaatccagg tacgttcaag ctttttttca ctttattaaa cgcagttgtt aatccttttt
    51421 ggatttcgtc ttgcgcaatc gtaaatttta aaacaccatc attcgtgcct tttttttcaa
    51481 atgttgcagt catttaattc cctccgagtt tagaaattca ttttatacat caaaaacgtt
    51541 tcatgcatac ctttaaatag tacactaacc ctttcaaatt gtaaacatat tgaatggata
    51601 gaatccttgt ttttcataac atttttatct ttttcactga taaaatctaa tggaagaaga
    51661 tcatttgctg caaaattttt tctctttttt ttaaaaaatc ttgtttttca tcttctgtac
    51721 cttcatacat cgtttttcct gtacacgcct ctacagtcag ttgaaaccag cgcttcgggt
    51781 cttcgatgta tgtatcatag acaggataaa caattgcaga ttgcaacgtg aattcttctt
    51841 ttaacacgga actaagcagc gcatcttcat tcccgtaacg atctgaaaat acacataatt
    51901 gctggtaact tgcctgctgc tgcggctttg gcagatcttt tggtatgact ttgactaact
    51961 tttcttcaat cgtcaaatag aaaacaggat ggcattcgtt caattgccta agtgtctcca
    52021 gtaattttgc ccttgctaaa atatggacct ctggcgatac aataagttta ctcgctgttt
    52081 ggataaactc atgataagga agctgttcga tctcatcaat agacgcaagc tgacgtgcag
    52141 gttccaacga aggaagttcc tccgatttat tgtggagtgc cttgatcttc tgcctctcca
    52201 tttgtccgga taattcttct gcaaattgga ttttttcaat gacccgctgc tcgaaagctt
    52261 cataaaaatc tgtacttgct atcaattttc tagcatataa aaaatcttgt gtactgatta
    52321 acaagtcaaa ataaaattca gcaaactcct cattttgaag atactgtttt tcatgcaaga
    52381 gtgcttgctt caatgcttct tttttctcgt ccaactcgta aagacaaaaa acaagcaggc
    52441 tattagcctc aaagctttct ttcaactcgt aagctcgttg aaataattct tttgcctgct
    52501 gatattgctg gtttgctagt gcttgttgtg ccactcgcat taaattctca tatttttctg
    52561 gaaaatcaat cggcttcacg cagtgtcctc ctcttgctca tattcagctc atgttcaata
    52621 gtagcaaaac aaaaaaagca tgacaattaa aaataactga agcaccctct aaaagctaga
    52681 ttttagatct gacttttaga aggtgctttc aactgttact gctttttatt gctcatcagc
    52741 tgttgacttc ctggttgaac gctttgatca gattgatcgt aacaacactt gtattagtga
    52801 aaaaatcgcc cagatgttgc tttttctgat taaagactgc tggaagatac cctaacatca
    52861 gcaaaggaaa ttttagaatg aaccggcaag caccttctct aactaaaacg gttgaccagc
    52921 taagttcttc ttcatcaaag ctgatgactc gaataccaaa gatcattttc ccaatcgttt
    52981 ggccatgatt gaatttcgtc aataaaataa aatacgctag ataaataagt aaggctgtga
    53041 atccgtagag actcagataa gaatctgaaa aattaagcca acctagattt ttggcaatac
    53101 caagtgttaa acgcgtaata gctccgatac acaaaagatc gaccaagaag gcaaacattc
    53161 ggataaaaaa acctgcatag aaatacttag gaaaatcatt tgcttttggc ggttcatttc
    53221 ttgtgtccgt atactttttc catttacgtt gtttcttttt gatttcttcg ggcgtcaaag
    53281 gctctctttc aaaagagctc agtacctttt gggaaaagtt ggagtcaggt cctacagcag
    53341 gctgctgttg cttatctttt tcttgttcct tattttcatt tgaaagctct gacatgctta
    53401 ctcacctccg taataataca ttgcttttgg tgattccgct gtccctagat tctcaagaac
    53461 ggataagatc tgactagtct cagaaggctt caatccctgg aattctgcta gtttacttcc
    53521 taaccatgta ctagcaaacc cagatggcgt ggaagaatat tctactagtt ccgcatcttc
    53581 aagctgttgt tcctttcgta tagcttttaa agcatcttca ggaaatccca attcatcgac
    53641 taaacctact tcttttgctt ggacaccatc ataaatcctt ccatcagcaa tttttttgac
    53701 ttcttcttca gatttattcc gtccctcgct gacgattgct acaaaacgac tatatgcgct
    53761 gtcgatatat gcttgaagca ccgcttcttc ttcttttgtc tctggtcgcg ttcctgaacc
    53821 catatctttc aacgctccgc ttttaactgt tgtatcttcc acacccagtt tttctagaag
    53881 tcctgaataa ttcaatcctg acatgatcac accaattgag ccggtcactg tttcttctgt
    53941 tgcaaagatt ttatctgctt gagcagaaat atagtagcca ccgctagctg ccatgttttt
    54001 catgctgaca tacattggga tatcatgttc tttacgaatc gtatccaatt tcttagcgat
    54061 ttccgcactt tcgtagacac cgccaccagg agaatttact tctaaaaaga tacctttgac
    54121 tgttggatct tcttcaatcg ccttcagttg ttccataaaa tttttatgat tgtaaccttc
    54181 agaagcaaat aaacctgaag accctcccgc agcaatcgtt ccatctactg ataattttac
    54241 gattttttgc gtactgtctc cctcttccaa cacatttgga gctagttctt catccccata
    54301 taaccaactg ttcaatccct caatttgatc gttttcctga ggcttagtca aactagctga
    54361 aactaacgaa accacaaata atcctgcagc aatcagaact gctgcccaac gtcttttatt
    54421 cattctttct cctttctaat acaagttttt tatgacgatc acagtttctg actgctcaga
    54481 agtgtcgaac cgctctgctt tttcttcccg cgcatacccg gaaaacgact cttttgttaa
    54541 ttcatcttct accgtaaact cacgagcttg agcaacttcc aaggcatcag gtgcgatttc
    54601 ttggatgcta tcccagccag tatctaaaaa tattttcgta tcatctgata caccagctga
    54661 tgcttcgaat ttggacaatt gtttttttaa cattcccagt gtcatgatct caatttttga
    54721 atccattttt actcctcctc tatccgatta ctttctattg taccgaactc ctgaaaaaga
    54781 tgatagataa aaacccatta ttttttgaca taaaaaggac atttgacaaa gaatttgata
    54841 tataccaatt tattttttat tctttttttg ttgacaagaa cattcgcaaa aggttatgat
    54901 tttaaatgtt tccagataaa aaacaaaaag gaggatagtt atacctttta ggatagcgcc
    54961 aggtctgtgt aaacagatga cgaggagagg gtttatcgaa agattcggcg gatggcccta
    55021 gggactgcac tctacagaaa atccacaaaa aatgtctgca aagataaaac aaaaggattt
    55081 tcctgcagct ggaagcattc atacgaattc attatagaaa gtaggatgtt ttttatgtgc
    55141 ggaattgttg gaatgattgg attaaaaaat gtaacaccag gattgattga cggtctagaa
    55201 aaattagaat accgtggtta tgattcagct ggtatctttg tctcagatgg cacaactgat
    55261 tatctggtca aagcacaagg cagaattcaa aatttgaaaa acaaaataaa tattgatact
    55321 acaggaaata taggtattgg tcatacacga tgggcaactc acgggcaacc ttctgaagaa
    55381 aacgcccatc cacatacttc ccaaagtgga cgcttcgtgc tcgttcacaa cggcgtaatc
    55441 gaaaactttg aagaacttaa aattgcttat ttagcaaatg accactttat tggtgagacc
    55501 gatactgaga ttatcgctca tctaattgaa actttcgcga aggatactac aacgcaagag
    55561 gcgtttttaa aagctttgcg ggtcatcaaa ggttcttacg ctttcgcttt gattgatcgg
    55621 acagcacctg atgttattta cgtcgctaaa aataaaagtc cactattaat cggactcggc
    55681 gatggattca atgtgattgc cagcgatgca atggctatgc ttgctcatac gaaggaattc
    55741 gttgagattg aagatgaaga gatggttacc gtcacatcag aaaaagttat tattcaaaat
    55801 tttgcaggtg acatcgtaga acgttcttca ttcgaagcac aagtagatgc ttcagatatc
    55861 gagaaaggta cctatccttt ttatatgctg aaagaaatcg acgaacagcc tattatcatg
    55921 cgtcgtatcg ctcaaaaata cgtaacagaa gacaatcgtg tctctcttga tcaaaagctg
    55981 gtcgatacat tgtctgatag cgatcgaatc tatatcgttg cttgcggaac tagttaccat
    56041 gcggggttag caggtaaaca gactttggaa aaattgacac agattcctgt tgaggttcat
    56101 ttagccagtg aatttggcta taacacacct cttctttcaa aaaaaccatt ctttattttc
    56161 ttgagtcaaa gtggcgaaac agcagacagc cgccaagtgc tggtaaaaat caaccgtctc
    56221 ggctaccctt cacttacgat tacaaatgtt gctggttcta ctctttcgcg ggaagcatcc
    56281 tttacactgc tattgcatgc tggacccgaa atcgcagtag catcaacgaa agcttatact
    56341 gcacaaatag ctgtactaac tttattagcc aaagctatcg gtgataaaaa agaatttgaa
    56401 acttctcttg tattcgatat cactcatgaa ttgagtttag ttgctaatgc gatggaatcg
    56461 gtcatcgccc aaaaagatta tttagaagag ttggcagaag tatatctcag cgatacaaga
    56521 aatgcctttt acattggacg tggtgctgac tacaacgttt ctcttgaagc tgctttgaaa
    56581 ttgaaagaaa tcagttatat ccaggcagaa ggttttgccg ctggcgaatt gaaacatgga
    56641 acgattgctt tgatcgaaga aggaacacca gtgatcggaa tcatcagtga agaagtgact
    56701 ggtgcgcata ctcgaggaaa cctgaaagaa gtcgaaagcc gtggcgctaa aacactagtt
    56761 attgtctcag agggattaga aaaggaaagt gaccagctgg tgctaccaac tgtccaccct
    56821 tatctaacta ctctaaccac agtcgtaccg actcaattac ttgcatatta cgcaacgcta
    56881 ttacggggat tcgacgttga caaaccacgt aatttagcga aatcagtgac agtagaataa
    56941 taaaagaaca aggaccagtg tcagacatct gacactggtc cttgttcttt tattttttat
    57001 gaaaatatct cttaatccag tccgatttct tctttgacta ctgccgcgat tttatcgaca
    57061 tagtaattaa ctttctcatc agtaggcgct tctgccatca ctcgaagtaa tggttctgta
    57121 ccggaaggac gaactaggat tcttccttct gatcccattt cagcttctgc ctcttcaatc
    57181 acttttttga ttgccggaac atccatcgca ccgtttttat cacttacgcg gatattcact
    57241 aatttttgcg gatagattgt tacctctgct gcaagctctg ataatttctt acctgtctgt
    57301 ttcatgatat tcagtaactg aattcctgaa agcatcccat ctccagttgt gttaaaatct
    57361 aagaaaatca tgtgcccaga ctgctcgccg ccaaagttat aatcgttttt gcgcatttct
    57421 tctacaacgt aacgatcacc aacttgtgta acgacatctt tcaaaccgat tccttccacc
    57481 gctttgtgga atcctaagtt actcatgaca gtcgtaacga tcgtatcttt tttcaatcga
    57541 tttttttctg ccaagtattt agcacagata aacatgattt tatcaccgtc gacaatgttt
    57601 ccaagttcat ccaccgcaat aatacgatcg ccatcgccat cgaaagctag tccagcatct
    57661 gctccttttt caacgaccat ctcagctaaa cgttctggat gggtagagcc tacgccgtca
    57721 ttgatattta acccgtctgg atttgtgccc attgtataaa aatctgtttc aagatcggca
    57781 aacaaacgat taacacttgt tgaagttgct ccgtttgctg catcgacaca aatggtcaaa
    57841 ccggaaaggt caccgttgat cgtttgtaca aggaattgag aatatttcaa taagccttct
    57901 ggaaattctt ctacagttcc caatccttca gctgatggac gaggcaattc atccacttca
    57961 gcatctaata atgcttcaat ttctagctct tggtcatcta ctagtttaaa accatctgca
    58021 ccgaaaaatt tgattccatt atcttgtgct ggattatgag aagcagaaat catgacccct
    58081 gcgcttgctt tttgcaaacg tgtcagataa gcaacacctg gtgtagagat cacacctagc
    58141 tggaacactt cgatacccac cgataaaagt cctgaaatca gcgcttcttc taacatttga
    58201 cctgagattc ttgtatcccg ccctactaac acgcgtgggc gttttccttc ttcttcatgc
    58261 tggcttagga cataacctcc gcaccgtccc agcttaaatg caagttctgg cgtaagttcc
    58321 ttgttggctt caccgcgtac gccgtctgtt ccaaaatatt tacccatagt tgtaaaatta
    58381 ctcctttaac ttaattttct gaggaatttg ttctgctcat ttgtgttgat tcgcttgttt
    58441 ctgatgtttc ttctgtactt gtggtcgagc tgcttgtccc agattccgaa ctggaagaaa
    58501 tggttgttgt cgatggttcc gttcctgaat cagcagatga aatacttcta ctcgtacttg
    58561 tattttcttg tgtccgactg ctcgtcgaag cagagctact gcttgacgtt tgcaacacgg
    58621 gtgtaatctc cacactaact gattcgggct tgatacttaa cccctcttct actggtattt
    58681 caattttacg agttgttcga tgattgatac ctgagacatt gatcggtaca gcaatactgt
    58741 caccgatcga tgcaagcaaa tcgctagagc cgcttacttc tgcttccagt tttgaaaaac
    58801 tgaaatcata gctttctacc ccggcagctg gtgttccttg ctgtatccca taaagtcgta
    58861 ccgacttgct tggcttgatc gaatcagctc tcactgttac ttgcactgga tcagagacga
    58921 tacttaatac ttcccctgct gcattcagcg cctgtattgg gacctcacta ttaatcccat
    58981 catctgtgac catcgaagcg tccacatcag ctactactcg tttgatttct gccaatgttt
    59041 tgtcacctgt agtgatagag acttttttag gactaacgga agtatcatca agttcatatc
    59101 cagatggtgt gaacgttgaa ggaatcaacg tttccacatc gaaatctttt attacctttt
    59161 tctcaaccgt tactgtaata gtcgatggtt cgatctttgc tgtgacagca ctgctcaaat
    59221 tttgaatttt tagcggaact tcatgtgttc cttcgcccag cttagtgata tctgctgtga
    59281 cgcggaacat ccgtgtatct tcgtttgcct ctgcattcaa ctgaactcgg tttgcactgg
    59341 aaagtttgac agtcactgca ttttcatatc catggatata gtagcgcttt gaatcataag
    59401 aaatcttgat cggcaccccc gtaactgttt gattatacgc ttcatttcca gaaagcgtat
    59461 ttggaacgga ctggccattt gcattgaagt acagcgcaat actgaacagc aatgcaataa
    59521 aactgtaaag aatgcttgtc cgtttctctt ttgagatcat ttgcgatccc ctcccttagt
    59581 cataccgtct aggaaagatt gaatcacgtt tttcttgttt tttgttttct cttcagcaat
    59641 tagttctcta cgcaagattg ccaaatattc ttgctgggat aagccagcca tcagttcatt
    59701 atctaacgtg atgctgacgt ccccggtttc ttcagagaca acgatggtaa tcgcgtcact
    59761 gacttcgctt ataccgacag ctgcccggtg tcgagtcccg aattctttag ggatcaacat
    59821 actttctgat agaggaagat aggcgcttgc tactgcgatc tttccttctt ttacaataac
    59881 tgcaccgtca tgcagcggtg tattaggaat aaagatattg atcagcagct ccccagtgat
    59941 atctgcatct aaagcaatcc ctgtctcaat atactcatct aatccagtat gacgttcgat
    60001 agtgatcaac gcaccgattt ttcgcttgga catatattgg atggctttgt caaaagacaa
    60061 gatcatcttc tcatcttcct gctgttcgct ttttgattgt ttgaaaagcg aactgcgtcc
    60121 aagatgttcc agtcctctcc ggatttccgg ctgaaaaatc acgatagcag ctatcacccc
    60181 gtacgtaatg acttggttca tcagccaaga caaggtgtgc agaccaatga tttccgctac
    60241 gattcggata acaataaaaa tagctacacc tttcagaagc tgaatcgctt ttgtgcctcg
    60301 cagcagttgg atcagtttgt atacaagata ccagacaacc agaatatcaa gtatgttcac
    60361 caaaaaattc agagagaaca agtcaccgga aaacatttgc tgccaatagt ccaaattaaa
    60421 aagttccccg atttgaaatg acataaaaag cctctcttct cttttgagat ttcctctcta
    60481 gtatatcata tgttttaatt ttagaggctg atatgctcgt atttttcttg agaaaaacgc
    60541 ataattttca agaaaattgc aagtatgcgt tttatttttc tctgcaataa atatttttaa
    60601 acttcagaga attattcatt atattttttc tgttattttt cctttttttc ttttgtagct
    60661 tgttccattt ttttacgtcg ttctgctctg gcagctcttc tagcagctct tctttcttct
    60721 gcttcaaggt ccgtcgtttt ttcttttcta gtcttaacgg gtacatcgat agattcctct
    60781 ggttcaagtc gtttcttgat tttttctaat tctcccgtca gtgcagcata gttgtaaaaa
    60841 cgtgttttag cgtcgtggac agtcttttca aataaagctt ttgcaagatt tggatttgcg
    60901 ttatctagcg aggaaaagcg aacttgtttc ctcatgaaat caggcatagc agagaaatca
    60961 ggttttttgt agtccaaagt cattgggttc ttgttttttt cgaccattgt agggttatat
    61021 cgatataatg accaataacc agaagaaaca gcttcttttg cttctttaag cgattctttc
    61081 attccgccaa gcaagccatg tgtgatacaa ggcgtatagg caataatcag agaaggacca
    61141 ggatactttt ctgcttcttc aaatgccttg atcgtttgca tttgattggc acctgaagca
    61201 atttgcgcca cataaacatt tccatatgtc atcgccatca ttcctagatc tttctttgaa
    61261 gcatactttc cactagccga aaatttagcg attgccgaag ctggtgttgc ttttgaggtt
    61321 tgaccgccag tattggaata gacttcgtta tccaaaacaa ggatattcac gtctgctccg
    61381 ctggcaagta catgatcgat cccgccaaaa ccaatgtcgt aagcccatcc gtctccacca
    61441 atcatccatt ggctgttttt tacgaataga tcctttctct tgtatatatc ctccagttca
    61501 gggaaaattg atcgttcgct ttcgatcgca gcttgcagtt ttgctgctct ttgctgcgtt
    61561 ccttcactct caaacatgtg tactaaccag tcttccatca attctcgtag ttcttctgat
    61621 acttttggca atacttcttt gattgaactt gccaaagcct cgcgacgagt ctgtgccgct
    61681 agaagcatac cataaccaaa ttcagcatta tcttccaata aagaatttga ccatgcaggc
    61741 ccttgaccac attcattggt cgtataagga gaagcaggag aaacaccgcc ccaaatagaa
    61801 gaacagcctg tcgcattcgc gatcatcatt cgatcaccga acatttgtgt caataatttt
    61861 acataaggtg tttcgccaca gcctgagcaa gcgcccgaga attcaagaag cggttgattg
    61921 aattgtgtag acaagacagt attctttcct ttgactggat ttgctttttg tcttaatgtc
    61981 attgcaaaag cccaattcac agcttgttct ttctgttctt cataaggctt catcactaaa
    62041 gctttttctt ttgcgggaca agcctctaca cacagaccac aacctgtaca gtcttccact
    62101 gaaacttgga tacggtattt tacgccgtct gcgcctcgca tttctctcac gataaatcct
    62161 tctggcgctt cttccatttc ctcttcatct gctaaaaatg gacggatggc agcatgagga
    62221 caaacaaagg cacattcatt acacatcgta cagcgatcac taatccactc aggtacttct
    62281 aaagcgacgc cccgcttttc catagaagcc gttcctaaag gcatttcgcc agttgtcatt
    62341 ccatttgcta caagtgtacc aacagagagt tgatttcctt cctgtgcatt cactggttca
    62401 agtatttctt gtatataacc agtgttcctt ttattgattt tttcaggcat ctccaacgtt
    62461 ctccaatggt ctgggatcgc gacttgatga agcagttcgg tcgtccgatc gattgcttgt
    62521 atgttttttt ctacgatagc cattgattta tgtccatagc ttttcagggc ttcttctttt
    62581 agcagcggaa gcacctcatc aaaaggaatg atgtcagcta atttaaaaaa agccgtttcc
    62641 attgccgtat tgatccggcg tcccaaaccg acttcttggg ccaatctcat ggcattgatc
    62701 gtatagaatc taatgttatt ttcagccaag taacgtttta attttaaggg cagatgcgtt
    62761 tctaattgtt cgtcgctcca aagagtattc aataaaaaaa tgccacctgg cttcaatcct
    62821 ttgaccaagt catagctatg caggtaagct ggtgtgtgac aggcaacaag gtccgcatgc
    62881 tcgacaagat acgctgaacg tatcggcgta tctccaaaac gaagatgaga gacagtcaga
    62941 ccgccagatt ttttcgaatc ataataaaaa tagccttgcg catatttatc ggtgtgatct
    63001 ccaataatct tgatagctga tttatttgct ccaactgttc cgtcagatcc aaatccccaa
    63061 aacttggcct ggaatgtttg cggttctgtc aaatccagac tttcctttgg ttccaaagat
    63121 tgataagtca catcatccac gatccctatg gtaaaccgtt ttttgcgtat gcttgggtct
    63181 tttttcaatt catcaaaaac tgctgagatt tggtcgggag tcacatcttt agaccccaat
    63241 ccgtagcgac caccaataac agccgggcga agttcagaat catataacgc actttgaacg
    63301 tctaataaga gaggttctcc acctgcccct ggttctttac ttcgatcaag aacagcaatt
    63361 gtttttactg tatgaggcaa cttttgcacg aatgtttcca ctggaaaagg acgataaaga
    63421 tggatattca aaaaacctgt tttccgtccg tttgcattca agtaatcaat cgtttgttca
    63481 atcgtctgtg caactgatcc catagaaaca atgacttctt ccgcatcgtc tgctccgtaa
    63541 taagtcacca agtcataaga agttcctcgt aatcggttga tctctttcat atatttttga
    63601 acgatttcag gtaatttatc ataatagggg ttgatcgttt cccgttgttg aaaatggatg
    63661 tctggattct ggttcgtacc actaacagtc ggatgattgg gattcatccc tcgtttacga
    63721 aatgaagcta atttctcctg attgatcaga ggagctaatt cttcatattc caaaacttcg
    63781 attttttgaa tctcgtgact cgtacggaat ccatcaaaga aattcaaaaa agggacttct
    63841 ccttcaatag aagcaagatg ggcaacaggt gctaaatcca tcacttcttg tacactgctt
    63901 tcagctaaca tagcaaatcc tgtttgtctt gcagccatca cgtctccgtg atctccgaaa
    63961 atattcaacg catttgtcgt cactgcccga ctagcaacgt ggaaaacact tggcagtagt
    64021 tccccagcaa tcttgtacat attcggtatc atcaaaagca gcccttgtga agcggtatat
    64081 gtagttgtca gtgcaccagt tttcaatgat ccatggacca caccagctgc tcctgcttcg
    64141 gattgcattt ctactacttt tactggttga ccgaatacgt tttcttttcc tgctgctgac
    64201 cattgatcta ctaattcagc catggtcgaa ctgggtgtta ttggatatat tgcagcaatc
    64261 tcggtaaatg cataagaaat atatgcggct gccgtattgc catccattgt tttcattttt
    64321 cgcatgattc atcatccttg ttcatattct ctcttattat ctgttccatt ataacgtaaa
    64381 acatgccatt tttttctttt atttataaaa atattttaca tgtatctatt tgaattggtc
    64441 atctaatttt tagacaaaca gtctaaatcg ttgccttttt ttgtcagaca tgtataaact
    64501 ataagcgaaa gaggtgtttt aacatggata tatcagtgat tgatgcaacg aaaacaaata
    64561 cacaaaaagg aatcctttat ggttcatcga atgctcctaa aaaaatggtc gaattcatca
    64621 acttagcttg tccgtattgc cgacaatggt ttgaagaatc ttatgagcta ttagaagaag
    64681 cagtccaaag cgggcaattg cagcgagtga tcaaattgtt cgataaagaa aaagaaagct
    64741 tacagcgagg gaacgtgatg caccggtatc tcacaatcag cgatggccaa aaagcgatca
    64801 aagagatcaa acaaatattc gatactcaag acgagtggaa acatctttct ctccaagaag
    64861 tagcggattt tgcagtagat aaactaaagc tgacagaaca aaaagacgaa cagctgagcc
    64921 aagctgtcat caacgaagct gagcaagcac atattcgatt tgttccaact gtcatcttgg
    64981 gtaaagaaat ctttgatgaa tctatttcaa tagaggaatt aaaagaattg atccaaacaa
    65041 aataaaaaaa taaggagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    65101 acgtataaac ggcggaagca gaagcaactc cttcttattt cttggagtta aacgcttctg
    65161 tcccagcctc cttattccga ataaatggtg tccaaaagct tgcatctgcc agattatctc
    65221 atttcttatg acaagctaag caaattatct ccaccaaata atttattcat atttttgact
    65281 tgcgcatact aactaattct taaattttca tacaaaattt ctcaatttcc cttaacgagt
    65341 aatatttatg tacggtgatt ctcactagta tcccaatcac tttttaagtt atcccgattt
    65401 caattctact tcaaaaatag ttgcttttat gtatgctgtt agttgattag atggtcattt
    65461 gttgagctag gtcgtttatt ttaaacaagt tgtttcttta gcttatacct atctcgtcta
    65521 ccaaacgcaa gatggcaaac acaaatgcat acgcatctgt atttgccact ttgattcgta
    65581 taaagctaac aactattaac tcctctcagc taatagttgc tctctttttt attcagattc
    65641 atttttgctg atcacagcct agtatttcaa tggttttgaa cactaaacca aattgttcca
    65701 ttacaacatt cactggctga tgaaatggat tagtagattt cgattattca aagcgatttt
    65761 ctattggtgg atcgtgttcc caactaataa gacggattcc aaacctatcg tacagatctt
    65821 ctaaaccact tataaatttt gcacctattt caggtgtttt attgcgtgga tattctattg
    65881 ttacgccatt aaatggatac caattaggat taggctctct ttttttctgt acatctccca
    65941 tagaatagtt agcactttct gggacataat atattcttcg accatcctct aattcatcta
    66001 ataagatatt tcgtgatcgt ctatcacttg ctaaatgtag acgccacgtg cgataccatg
    66061 ccatgctacc tgcatctgca gaaaatccat caaataatgc aacaattgta tcttctatca
    66121 caatcctttc cccatctact tcatattcta atctaaaatc aaactcccct cgggtaattt
    66181 ctggtcttgg tggcttagga cccaatatta ttctacttaa aaccgcattc gttcccagat
    66241 gaaacacagc tataacaaca ataatgatta atattttgtt tctatttgat aaatttctca
    66301 ttattcgcac atcacctcta cattctcaca tattagttcg taatactcct ttaatatcaa
    66361 aatatctact ggtcgtaata atattcgcta tgaattccta ctactcgtat aagaaaggcc
    66421 aaatcatcag cttttacttg ctgatgattt ggcttgtttc tatttatcgt aattgttttc
    66481 taatcaccaa aattgttaac aatcggttca gatatttccc agttgattaa ggtaattccg
    66541 tattgtgtca aaacttcttg cgcttctccg aaattaagta cagttcttat gtatccactt
    66601 tctcctaata taaagtctac ctctctttta aaaccttcct cgagatttct aagggctata
    66661 tgtggtttta atgacattga ttgtacattt tcccccatat aatattgcgc acttcctcga
    66721 ctaaaataga ttcctagatc gtccccaaaa ggtagatctt ctctaccact agctaatcta
    66781 cttctccatc ttcgttctct tttcatagaa cctgcgctga actcacaccc gttaaactca
    66841 gctatgacag tatcttcaat tatgttaatc tgtccatcta gttcgtattc aatcctaaat
    66901 ggaaattctc cataggtgat ttccggttcg ggtattttag gtgagattaa tgcaaagaaa
    66961 ggaaatatta agcttggcaa catcaaaaaa actcctccta tgatcacaat tcccgatgta
    67021 atccaaaata taatttgtac aattctcatt gatccattgt attccatttt attcccccta
    67081 ttactattca tatccgccta tctatatcga tcttccaatg cagagataat tgcttccata
    67141 ccttgatttt ttactgagtt acctatgcga gatatcattc tccactaagg tgcatcatat
    67201 tgtctatcta acatgattaa ttctccaata ggtgtatact cctccaaaaa caacatttaa
    67261 tgcatctccc tcgacaacat aagctaccat gtttgctgta tatgtgtttg agtctaattc
    67321 ataagcagat aaatttactg tcgctggatt aaatataatc gcattcgtat ttatagctac
    67381 tgaatttgct gcttcagcac caccttttga atgtccgatc attgtgattt caatagtagg
    67441 atttacgtgg acagccctca ccgtttaccc tgaccattat agaaatcgct tacttttttg
    67501 aactacgcaa caaaggatac aatgctccta acttcactgt ctccattttt gtccactaag
    67561 gaatataaaa aataggcatt aattcattta attcggtcac aacacgttac cttttaaatc
    67621 attatactgt atctcataca ttattatcaa taaactatta taaaaatgca aaaaatgctt
    67681 tatcaatcta ttttgtaatt ggtcataata tcattgaaat cataccctgt atcgattttt
    67741 cctatgaatc tcgtctattt gtgattgacg aaaaagaggc aagacagaca ctggaatggt
    67801 aattttaccc actattttgc tccaactatt tgtaatcgta cccacttttg aaataccgag
    67861 atgatcattt taattgatat gctgattccc aagcaaaacc ccaagaaatt aaatgctcta
    67921 tcgcatctag cttcttgggt tttgcttata taaattccaa catttaaatt ttttatgctg
    67981 ttcggtctca gaaatgccgt ttttgcttat atcacaatat caagatgtca aattattcgt
    68041 gttgccgatg actttgatta atttttttca aattgtttat taagactaat gctgtctttt
    68101 tgcagatacc aatgttcgaa ctttttaaca ttatcatatg atcctgcaag ttttaacttc
    68161 ttaccattag atgttatcaa agttataatt aaccttgcct ttttcccatt aggatctttt
    68221 attttatgaa ttttctgcag gtaatctctc ctaatggcag ctatttttac ctcatcagtg
    68281 ctgataaacc attgatcatc cacatacata ctgcctgtta tgttgtgttt ttccatttct
    68341 tccgagaacg aaaagtttaa ggctcgttct tacttccaaa gttgaatgag tccatggatt
    68401 ggacttagtg tgagaattga gaacaacaat aagaatccat atcctcccgc aaacatccct
    68461 aaggctatac tgtctctcca tccataagta ggattagaag agaaaagagt caccgtttgt
    68521 aataatatga aaaggaataa tccagcacaa acaccaaaga taacaactcc aaacattgaa
    68581 tttttataca atgaccattt atttataggc ttttctttca ttttacttcc ccctactgtt
    68641 ctgttcacac ggaatgaatt caaagttcat aagccctcct ctttgaacat atgaatacga
    68701 cttgctaact atactttaaa aaagcttgtt ttaagcggtt ataggcgagt tgtaatctct
    68761 attcatctca ttagcaaata acttgccgaa aagtctactg aaattaaagc agatagtgga
    68821 agaattattt agccaggata gacactattt gtgaaacaca tgtctttact tttgaaattc
    68881 tatgatgaaa agccttggaa tacagtagct cttaattggt aatacttttt ccattataaa
    68941 taacctcttt tcattttata tttatcccct ctaaaaataa tatctaatct aatattttaa
    69001 acttatattt ccctcgctgt gctaatagag cattactaaa taaatagaaa ctagaaaaaa
    69061 gcattacgcc tgccagaata aaccaattat ttgtat
//
LOCUS       DAFEML010000007        67762 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFEML010000007
VERSION     DAFEML010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.007"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(98..1228)
                     /locus_tag="LP468_000560"
     CDS             complement(98..1228)
                     /locus_tag="LP468_000560"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL2080123.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="LP468_000561"
     CDS             complement(1877..3079)
                     /locus_tag="LP468_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2080124.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="LP468_000562"
     CDS             complement(3139..3342)
                     /locus_tag="LP468_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL2080125.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="LP468_000563"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="LP468_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="LP468_000564"
     CDS             4879..5691
                     /locus_tag="LP468_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080126.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="LP468_000565"
     CDS             complement(6715..6867)
                     /locus_tag="LP468_000565"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2080127.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="LP468_000566"
     CDS             complement(7058..7936)
                     /locus_tag="LP468_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2080128.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="LP468_000567"
     CDS             complement(7975..9093)
                     /locus_tag="LP468_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL2080129.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="LP468_000568"
     CDS             complement(9090..11189)
                     /locus_tag="LP468_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL2080130.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="LP468_000569"
     CDS             complement(11240..12061)
                     /locus_tag="LP468_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2080131.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="LP468_000570"
     CDS             complement(12058..12867)
                     /locus_tag="LP468_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2080132.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="LP468_000571"
     CDS             complement(12889..13383)
                     /locus_tag="LP468_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2080133.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="LP468_000572"
     CDS             complement(13395..13883)
                     /locus_tag="LP468_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2080134.1"
                     /translation="MFLKVGTGIAYMKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDYEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQEIKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="LP468_000573"
     CDS             complement(13960..16656)
                     /locus_tag="LP468_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2080135.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKEYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLKHILSSEMKPVEFNRLIQELIKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKAEEPNYDMKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="LP468_000574"
     CDS             complement(17084..18157)
                     /locus_tag="LP468_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080136.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="LP468_000575"
     CDS             complement(18154..18981)
                     /locus_tag="LP468_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080137.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="LP468_000576"
     CDS             complement(18982..19788)
                     /locus_tag="LP468_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080138.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="LP468_000577"
     CDS             complement(19800..20885)
                     /locus_tag="LP468_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080139.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="LP468_000578"
     CDS             complement(20902..21444)
                     /locus_tag="LP468_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2080140.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="LP468_000579"
     CDS             21702..22691
                     /locus_tag="LP468_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL2080141.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="LP468_000580"
     CDS             22688..23425
                     /locus_tag="LP468_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL2080142.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="LP468_000581"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="LP468_000581"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL2080143.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="LP468_000582"
     CDS             23989..24621
                     /locus_tag="LP468_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2080144.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="LP468_000583"
     CDS             24706..25353
                     /locus_tag="LP468_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2080145.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="LP468_000584"
     CDS             25358..26341
                     /locus_tag="LP468_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBL2080146.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="LP468_000585"
     CDS             complement(26744..28258)
                     /locus_tag="LP468_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL2080147.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="LP468_000586"
     CDS             28396..29202
                     /locus_tag="LP468_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080148.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="LP468_000587"
     CDS             complement(29377..29946)
                     /locus_tag="LP468_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080149.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="LP468_000588"
     CDS             complement(30029..32089)
                     /locus_tag="LP468_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL2080150.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="LP468_000589"
     CDS             complement(32366..33844)
                     /locus_tag="LP468_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080151.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="LP468_000590"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="LP468_000590"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL2080152.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="LP468_000591"
     CDS             complement(35150..36070)
                     /locus_tag="LP468_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2080153.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="LP468_000592"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="LP468_000592"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL2080154.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="LP468_000593"
     CDS             37799..38332
                     /locus_tag="LP468_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL2080155.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="LP468_000594"
     CDS             complement(38822..39346)
                     /locus_tag="LP468_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080156.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="LP468_000595"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="LP468_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL2080157.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="LP468_000596"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="LP468_000596"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL2080158.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="LP468_000597"
     CDS             complement(41068..41748)
                     /locus_tag="LP468_000597"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2080159.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="LP468_000598"
     CDS             41874..42743
                     /locus_tag="LP468_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2080160.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="LP468_000599"
     CDS             42769..43284
                     /locus_tag="LP468_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080161.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43924)
                     /locus_tag="LP468_000600"
     CDS             complement(43331..43924)
                     /locus_tag="LP468_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080162.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="LP468_000601"
     CDS             complement(43949..44128)
                     /locus_tag="LP468_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080163.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="LP468_000602"
     CDS             complement(44205..44714)
                     /locus_tag="LP468_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080164.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="LP468_000603"
     CDS             complement(44810..45190)
                     /locus_tag="LP468_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2080165.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45519..46268
                     /locus_tag="LP468_000604"
     CDS             45519..46268
                     /locus_tag="LP468_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL2080166.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46452..47729)
                     /locus_tag="LP468_000605"
     CDS             complement(46452..47729)
                     /locus_tag="LP468_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080167.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47808..48452)
                     /gene="pcp"
                     /locus_tag="LP468_000606"
     CDS             complement(47808..48452)
                     /gene="pcp"
                     /locus_tag="LP468_000606"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL2080168.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48651..49595)
                     /locus_tag="LP468_000607"
     CDS             complement(48651..49595)
                     /locus_tag="LP468_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL2080169.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49597..50283)
                     /locus_tag="LP468_000608"
     CDS             complement(49597..50283)
                     /locus_tag="LP468_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL2080170.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50757..51077
                     /locus_tag="LP468_000609"
     CDS             50757..51077
                     /locus_tag="LP468_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL2080171.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51231..52136
                     /locus_tag="LP468_000610"
     CDS             51231..52136
                     /locus_tag="LP468_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2080172.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIETIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52133..52906
                     /locus_tag="LP468_000611"
     CDS             52133..52906
                     /locus_tag="LP468_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2080173.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53087..54511)
                     /locus_tag="LP468_000612"
     CDS             complement(53087..54511)
                     /locus_tag="LP468_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080174.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54722..55168
                     /gene="nrdI"
                     /locus_tag="LP468_000613"
     CDS             54722..55168
                     /gene="nrdI"
                     /locus_tag="LP468_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL2080175.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55233..57215)
                     /locus_tag="LP468_000614"
     CDS             complement(55233..57215)
                     /locus_tag="LP468_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2080176.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57229..58125)
                     /gene="murQ"
                     /locus_tag="LP468_000615"
     CDS             complement(57229..58125)
                     /gene="murQ"
                     /locus_tag="LP468_000615"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2080177.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58128..59189)
                     /locus_tag="LP468_000616"
     CDS             complement(58128..59189)
                     /locus_tag="LP468_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2080178.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59400..59966)
                     /locus_tag="LP468_000617"
     CDS             complement(59400..59966)
                     /locus_tag="LP468_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2080179.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59994..61496)
                     /gene="eat(A)"
                     /locus_tag="LP468_000618"
     CDS             complement(59994..61496)
                     /gene="eat(A)"
                     /locus_tag="LP468_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2080180.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61754..62875)
                     /locus_tag="LP468_000619"
     CDS             complement(61754..62875)
                     /locus_tag="LP468_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2080181.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63001..63942
                     /locus_tag="LP468_000620"
     CDS             63001..63942
                     /locus_tag="LP468_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2080182.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64092..64988)
                     /locus_tag="LP468_000621"
     CDS             complement(64092..64988)
                     /locus_tag="LP468_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2080183.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65257..66597
                     /locus_tag="LP468_000622"
     CDS             65257..66597
                     /locus_tag="LP468_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080184.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66815..67258
                     /locus_tag="LP468_000623"
     CDS             66815..67258
                     /locus_tag="LP468_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2080185.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT        19969 a        13996 c        11787 g        22010 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaataa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagccca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcgcc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaaataa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tagccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataac gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccaac ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaaa atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt ccttttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgctggc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttatttcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt cataatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcactttcat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacataaa aaaaagtgtc
    13921 taacctgaaa aaatcagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tcgaaacata ataaaattca tcttcatctg gtttcatatc
    14101 ataatttggt tcttctgctt tttctgtccg cgccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata taaagattta gttttacgcg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacctcact catcacgatt gttgggttca gaaagttcaa
    14281 acggtctgcg attccttcca atgaaaagaa ttttatcagc tcctgaatca aacggttaaa
    14341 ttctaccggc ttcatctcag aactcaaaat atgcttcaaa ttggctgctc catcaccatc
    14401 taaaatatca tatacattga tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtat tccttcgtga aaacttcgat ggactcatcc gataaatgat gacgaaaaac
    14581 atccttcagt ttatccgaga tacccaatcc cgacatgcag gaaatgatga tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaac agaaagtagg tcctccaaga cactcttcct gttcccaata taataaatga
    45361 aagtaagaaa ttatattttc aagaaaacaa acagaaaatt atcataacac aaattattta
    45421 taattgaaag actagttttt tttcaagaaa agcatacaat agattgtgtt agtaaataca
    45481 gaacacacta catttagtgt cttaaggagt cctcatacat gaagtcatat tttcagtttt
    45541 tagctcatca gctaaaaggc tggccgcaac aaaattatta tcttttcttt ttcagtcttg
    45601 gctgccaggt catgactctt gtcaatagtc ccatcacttg gctgtccgtt attacattta
    45661 tcggtaccac gcttggtgta ttgtgtattt tatccatcaa tgcggcaaaa tcagtcaacg
    45721 gtattttagg tattttgtct gcgatttgtt ttattatcgt tgggttttca gcaaagaact
    45781 atttaagtat cggtgaacag attgcttata tgatcacatt ggatatcccc gtattgttaa
    45841 gtaaagaatg gaatcataat atggcttcaa aaatccgaaa attcactgga aaaagctggt
    45901 ttatcgcaat catcagtact ttccttgtct atcttgtttc aggattcctg attggtcgtt
    45961 atacagatga tcctcggccg tgggtagatg ccattgcttt ttctattagc ttgactgctg
    46021 gtatcatcag tttcttgcgt tacaacaacc aatattactg gtggttagct tcagggcttg
    46081 ctcaaatggt cctttggtat atttcattta cgcatggatc tgcaagtttg gcgatgttcg
    46141 tgaacagctc tgtttacttg ctgaatgatg tccttgcatt taccgtttca ccttggtata
    46201 accaaaaaga acgtgaacgt atgcaaaaaa tggaagaaga atactacaac gcacaacaac
    46261 acgcataaaa aaactgagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa
    46321 cacgtataaa cggcggaatc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
    46381 tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca
    46441 gcctctattt tttatagtaa ttccttcaga tactttcttg cctcatcatt gaaacgcagt
    46501 gattcttcta acttctgata atattccaac gcttgtttct gagcttcagt aaaacgataa
    46561 tgttttcctt tccatttgtc gattgtctct tgcacatttc cagattggat atctttcact
    46621 actagttgcc atttttcttt tgagactgta cggtctttct tatcagcaga ttgtatagct
    46681 tctcgttctt tacgcaatac ttttaaaaaa ccatttctga ctatccgagg aatgctgtcg
    46741 aagaaccctt ctgtaaaacc atagtgacaa tattgcttcc aaataaatag atagattttt
    46801 ggttggatga atcgttggtt tttcgcaaaa tattccatct gagcagtgac ttctggtgtt
    46861 cgttgacgtt ttgtctttct caacacggaa ataaatgttt caaaataagc attaggatgt
    46921 actggcactt cttcatatac gatggattgc caatctttac gtaaaaatgc gcgatagttg
    46981 atcaagaatt cttctacatc ctttactaat tcttctgcaa agtcgtcaaa tagttctttt
    47041 tttatctgtc gcttttttga ctgcccattg atgtgttcac ttattttctt gatttcattt
    47101 tccaatgctt gataatccgc tatgtaaatc ggcatttcta cttggcgaaa ttctgcgagc
    47161 cgctgagcta attttatatc cggtaaatat ggctgtttca tccgacgatt ttggtacaag
    47221 acaaaacagt atttttgcca tagtccttca ggaaaatcga tattcttctg cttaagccat
    47281 aataattcgt ctaaggccag atcaactttt gtcattccct gatggatcga agctgccact
    47341 gtcggagaga catgcaggtg atcggcaaag tggttgatgc ctagttttag gatctttccg
    47401 gtttttggcg atttaacgat gtattgcact tttaattctc taccacactc acaatacaat
    47461 ttttgctggc ttcgttttgt tcgaaaaaac ggattgatct tgaagtcaga aaacacccaa
    47521 tctgttgcag ctaaataatg ttcttccata aaacgagagc tgattagata tcggcggtgc
    47581 ttatcgacta gttcccgctg ttttttcgtt aattttgcat agatctccca acgttgactg
    47641 cttgtgtatt gtttagaaat tttgatggga tagcttttgc tgatttcttt tggaaaccat
    47701 tcttcaaaga cggattgcca ttcttccacg gctgtttctt tcctttctaa ttacaaaaag
    47761 ctggctacta acataacgtt agcaaccagc cagtgtttct tgctaaatta gtgagttgtt
    47821 ccggcatttc cggaaatatc ttctttattt tctactgctg cttcaactgc ataagtcaaa
    47881 gaagaagcaa tgtcttctaa agacatagaa ggcgtaccca ctggacgatc gatcacttga
    47941 tcgggtgaga atggcacgtg gatgaaccca cctcgaattg ccgggaattg tgtttcgatc
    48001 aaatgaagca aacgatacat gatatcattg cagacaaatg ttcctgctgt ataagagatg
    48061 tacgctggta gaccatgatc ttgtacattt tttgtcattg ctttgattgg caatgaggta
    48121 aagtaagcgg ctggaccgtt ttcttctaaa gccgtatcga atggctgatt tccttcatta
    48181 tcagggattc ttgcttctgc tagattgatt gcgacacgtt cgaacgagac tgctgaccgc
    48241 ccacctgctt gtccgacaca gatcacgaca tctggttggt gctgttggat ggcttctttg
    48301 actacttgac tgcttttttc gaatacggtc ggtacttcca ctttgatgat ttcagcaccg
    48361 ctgatttcat ctggcatttt ttttactgct tcataggctg gattcacttt gtccccacca
    48421 aatggatcaa aacctgttac tagtactttc atctgttgtt cctccgtccg attgatttaa
    48481 catatggtta tcttttatca taccattttc cttgaacagc gtaaataaag gaaacaatag
    48541 tttaaataac ataacagatc aaacttaata tattcttata aaaaaatagt gttccactac
    48601 aatgttagaa gaggttgcga caattattct gtcacaaccc ctctcttcta ttatttaaat
    48661 agaatcatat aagcaatttg gaaaactagc ataaataacg caataaacaa ctggtttttg
    48721 atcactccgt atttgtcttt catctccagc atcgctacag gcacgatatt gaagttagca
    48781 gccatcggtg tcagcagggt cccacaaaaa ccgcaagtca atgcaaccat tcctattaac
    48841 gctggattcg ctccatgact aaatacgaat ggtgcaccga tcccaaccgt catcacggtg
    48901 atggccgcaa atgcattccc catgattacc gtaaatatca ccatgccaag agcgtaaatg
    48961 atgatgccga tgttcacatt tccttctgga acgatcgtac ctactgcatt ggaaatcact
    49021 gtcccaactc cagcgcttgt aaataccgca cctagagaag ctaaaagcat tggcaacatg
    49081 cttaacggcc ctactgtgcc cagcatatct gctgcatcat ctaaaaatgt acttggtcga
    49141 ttatctcgag aaaagaacat caagattagc atggctgcaa aaacaccgac gcccacgccg
    49201 actaaagcac ctaaattggt aaatagagca aacaagatcg caaagacacc gatactcaaa
    49261 gctggaataa aaattttcat tcctagtttg tctgacattt tttccatata ttcttttgat
    49321 ggaagccggc tttctccttt gctgactttc ttagcaattg ctggtatggt catcgcaaag
    49381 atcaagccac cgttcacgat tgccggaagc catcttcctc ctgcaataac tacccctaag
    49441 accgtccaga aaaaggctga cccataacga tgaggattgg ttttatctgt taaatttctt
    49501 actccagtgt aaatcaatac gagtcccatc acgatataaa ggatctccag taatttatcg
    49561 cctaataaaa tatcaggatt tgtaaaaaag tccatcttat tgcccctttc ctggataata
    49621 tttcttcgct aatttctttt ctttaagata gaagtagaca cttgccacaa ctaaagccgt
    49681 gatagccact ggaacttcca ctaaagcaag ctgtcccaat gttacgtcat atcctagatc
    49741 tttcagtgtt gattggacta gcaacgcccc tgctcctccg atgaatagta cttggccaaa
    49801 gaaccagcag acattttcca tagctgaagc catacctttt agttcttctt catgcttagg
    49861 atggacttct aacccttttg attcgatggt ccccaatgcc atcggtaaaa tgattggacg
    49921 aacaaatcca gcaactccac caaaactcac gttaaaagcc gcaaagatca ttcgaaagat
    49981 cccataaata tctacaatca taccagcaga tactttcttg aatcgcttga tcaaggaagc
    50041 cgctgattct ttcagaccat ttctttcaag cgttcctgtt gccaacataa tgatgataaa
    50101 aatcgccatc ccgcgattgt ttacaaaact tgtacctaaa agttctaaca ttccttgaat
    50161 gccaagaccg ccagtcaaag ctgtaacaac taaagcaacc attacgatca atatcgagtc
    50221 taatttaaat gcaaacccga gaataacaat caagacgcct aaaaggctaa gataattttc
    50281 catatatttt cctccataaa atgacaatat ttttttaatt ataaagcaaa acacataaaa
    50341 aatatagttg ttttctcacg aaatagacac tatttttaaa tatttttcgt tattttttta
    50401 tcacaaaaat tatcttactt attgtaaggt aaagcttttt ttaatttatt gcccgataat
    50461 atatagaaat aaggtctagt tactgttttt tttaaatgat taataaataa caacttcttt
    50521 ctatgaaatt gcaaagcatt catcttcttt tccgctaacg atatatccgt cagtgcttgg
    50581 tacactttac taaaaagtat gagattgccg atatctggat aggtgtgcta tactacagaa
    50641 aaagatatac aatctgccac cgggtaggat aaagaggatg atcattccat taggtctttg
    50701 aagggatgat tttcctcttt ttgtgtattt ttttatagtt aaggaggaat gtaagtatgg
    50761 catggatgga attaatcata gcaggaattt tggaagtatt ctggtcaacg atgatgaaat
    50821 ggagtgatgg tttttctaaa atcaattatt ctttttacac agtgattggc atgattgcta
    50881 gtttttactt tttgtcaaag gcaatcaaaa gtttgccgat gagtctctct tatcctatct
    50941 ggacagggat tggcgcagtt ggttcggtca taattggtgt ggtcttgttt catgataagc
    51001 tgaatctttc cacttggttc tttgtgggga tgctactcat cagtatcatt ggcatcaaga
    51061 ttactagcgg ccactagaca cttggaataa gtactgatca gaaaaaataa gcctttttat
    51121 ttaatattca atttttttat gaaaaaataa gaaataagtc caatgaccta gcgacttctc
    51181 cactcatcag gtgtatgctt gtactatcta tagaaaagga gtgaatattt ttgaaaagtc
    51241 tttcggtcca agaattatcc aagaactttg gtcacaaaca agccctcagc gatgtcagtt
    51301 ttagcttatc ccctggcaaa atcgttggat tagtaggtcc taatggcgct ggaaaaacaa
    51361 cgatcatgaa agctatttta ggactgatcc attactcaga tggaacaatc tgtattggtg
    51421 aaaatgagat ttctccctct agtcataaag ggttggaaca agtaggagca ttgatcgaat
    51481 acccgggtat ctatccattc ttaacaggct atgatcatct gaagttattc tctgaaacca
    51541 acgatgtatc tgctatcgaa actatcgtga atcagctcaa gatggaaaag tacattcaca
    51601 aaaaagcgaa atcctactcg ttgggaatga aacaaaaatt gggaattgct cttgccttac
    51661 tgaaccatcc gtctatcgtt attttagatg agccgatgaa cggtttggat ccacaagcaa
    51721 caagagatgt gcgaaaaatc attaccgact tggctactca gggcacctct ttcttgatct
    51781 ccagtcactt actcagcgag cttgaaaaaa tggtcgatga gctgatcctg atcaatcaag
    51841 gaaagatcat caaacaatgt acaatggctg aattgaacca aacagcgcaa gatttcatcg
    51901 ttatctctac aacaaatgat ctagctgctc gaacgatctt gacagaagct ggatatactt
    51961 tggaagatcc tgataaaatc aagcttttaa aagaaaacga agaattatta ggaaccgtga
    52021 tccagctatt gtctgcacaa aatatccatg tgacagacgt ccagcatctg acgaatgatt
    52081 tggaatcttc tctattggaa attctggatt cagtaaaggg ggaagaagaa aaatgacatt
    52141 gcttgtaaaa caagaattat ttaaattgat caagaaaaag tcaactgctg ttttatctgt
    52201 tctattagtt gttttgctca taggaacagc acttctagcc aaaaaataca cgacgatcat
    52261 tgatccagtt gaaatgactg ctcagctttt tagtgccaca tcttggattg tctttatcat
    52321 gattgcagct gcaagcacga tcatttcgat ggaagcacaa tatggtacat tgaaaaatct
    52381 cctttatcga aagtattctc gaggagaaat attagtaagc aaatggatca cattagttat
    52441 ttattctgtt tatttatacc ttttagctat tattgtcact gtgttgatga aactgattct
    52501 tttcccttcg atttccttca cggagaaggt ttctactggt caaacactga tccaaagctt
    52561 gttcacttat actttgggta gttatatcgg tttatggctg attttaagtt tagtgttgat
    52621 gattgcttgc tttatcaata gttccggcgc atccatctca gcaggaatcg tcttttattt
    52681 tgcttcgtca atcatatctg gtatccttat tgcactcatc caaaaatggg agtggatcaa
    52741 atggaatccg atcagtatgt tgaatctgca aaaccaaatt ggaaacgaag agatcatgaa
    52801 gcaattgact catctttcta ctaatcaaat gctattcggt aatttagctt acatcgtttt
    52861 gttcttagca ttaggatatc tcgtatttaa gcgaaaaaat gtatgatgac tcatcaaaaa
    52921 agaggctgtg aaagagacgt tcagccttat tgccgattgg ctgtctctta aacaccgttt
    52981 attctgaaaa aggagctgtg acaacatttg tgtcacagct cctttcctag tatgtttttg
    53041 aataaacgac aggctcacaa cctctcttta tacttctttt atacttctat acgtgaagca
    53101 tcccagtggc aaataaaacc attgcaatca ctccgaccat cgtcacacct ataagtaaaa
    53161 tcttatctaa gtggatatgt tgtacaggct cgttttgctc cttacgtgct ttgaggtaaa
    53221 aataaatgcc tggcaagaaa agaacaagaa caagcattac ttcattaaag gctacgacta
    53281 gcatagccca tacttgaaag gcacttgcta aaagccctac taaaaattgg acccattctt
    53341 tccgctgata agaaagtttc atttggtaca atcctaagaa aagccacgtg aagaaaatag
    53401 ctgctgtacc aagtgtgtaa gcaaagttat aagcactgtc agtgaataat aatgaaagta
    53461 aaaagacatt cgtacataac gtcgtcaata cgatagcata agttggtgcc ccatttttgt
    53521 tgagttttcc ccatgcttta ggcaaaagtc cgtcttcagc catgtttccc attgtttcaa
    53581 tcggtaagat cgtccatgag agccaaacac caactaaaga aatgatcaaa ccgccgttga
    53641 tcacgactgc tccccattta ccaaccatca tttcaaacac atagcccata gcaggctgcg
    53701 ccttgatcgt ttgcagctga ttcatcgtca ttgtcccata tggaagcatg gaaaccaaga
    53761 cgtaaataat aatcaagccg aatatcccta gaatcgttgc tttcccaaca tctgattgtt
    53821 tttttgctcg tgaacctacg acagaggctc cttcaatacc aacaaatacc caaagcatca
    53881 ccatgatgca actcaatact tgactggaaa acgggatcgg ctgtccattc gcattcaata
    53941 taatgtcgct agaaaagtta tcaatgaatt gttggatcga aaacgtgctg atagctacta
    54001 caataaataa aaataatggc actaatttac agaatgtgac gatagcattg acgaaactag
    54061 cattttcgac tccccgattc actagccatg catatcccca taaaaagact gtactcatca
    54121 cgatcgatgc cagattttgc ccaccttcaa atactgggaa gaaatatcct aatgcgctca
    54181 tcaacaatgt tgcaaaagct acgttgccta accagcatgt gagccagtaa ccccaaccgc
    54241 tgataaaacc agcgaaacgg ccaaaacctt cttctgcgta actaaagatc ccgcctttta
    54301 aatctggacg ttttttattg atattattga tcgacaagga gagcatcaac attgctgttc
    54361 ctacgagtac ccaactgaaa atagctgggc cgccagccga tccggagatg tccgtcataa
    54421 taccaaatac gccacctcca atcgctgaac caattactaa ggcagcaagt ggaattaaac
    54481 caattccttt tttctgttgc tctgtatcca tgtaagcatc ctccaaaata aaaccgcttt
    54541 tatcaaaaag tataacaaac cttttttatt tttacttaat taataaaaac tttaatagaa
    54601 atataattct accggctttt ttctcattat acaagcaaag cgcctagtcc ctttccaaat
    54661 tacaccacca aaaaacttaa aaaagatgct atactaaaag gaaagaattg gaggatgatc
    54721 catgaacatt ttatatatat cgatttcagg aaatacgcgt gcctttgcca aacatctagc
    54781 agaatatgct gaaaaaatgc atgcagaaga tcctgtcaat cctgaagtta ctttaaaaga
    54841 aatccatgaa aatagtgatt ttacgaaaga aacagaacca ttttttactt tcgttcctac
    54901 ttatttagac ggcggaaatg gtttagataa cggtgataca gaaatcttga ccgaaacgat
    54961 gcgtgaatat ctggaacatg aagacaatca taaactttgt cttggtgtag tcggtagcgg
    55021 aaataaaaac ttcaataatc agtattgtct aacagccaaa caatatgcac aaacatttgg
    55081 ctttcctttc ttggcagatt atgaattacg gggaacacca tctgatgtga cacgaattta
    55141 tcagatttta gcagaaaaca ataaataata aaaaagaaga agctgaaaaa tagatttcag
    55201 tttcttcttt cgtttctatt gtttctatca tattaagctt tgacatccat cacaggtgct
    55261 tttgcttttg ctttacctgt tttttccaag acaaagtttt ttacacgatc catattggtt
    55321 accaagacga tcatggatgt ttctttgcct gctgctttga tcgcttctaa gtcagcttct
    55381 gctacaagcg tatcaggtgt cacttgctgc ccttctgtta ctttcacatc aaatggcgta
    55441 ccgcctaagt caactgtgtt gattcccata tgaagcaaga tttctaaacc atttggcgtt
    55501 gtgatcccaa tagcgtgttt cgttgggaag acagagctga ctaccccagt aactggagaa
    55561 tagatatgtc cgttttctgg ttctacaaag tagccttcac ccatcatctt ttgtgcaaaa
    55621 actggatcac ttgctttatc taaagaaaca actgttccgt cagcaactga tgagaggata
    55681 gtcacacttt cagctgaagt ttgaggtact actttttcag gcacttcatt tactgtggct
    55741 gtttcagtcg ctaattcttc tttttctaaa cggtctttag gaataccgaa gaagaatgta
    55801 gcaacgaagc caccagcata agctgccaat aatccaagga tgtagcctaa ccatttaccg
    55861 tcagagatca atgggatcaa agcggctcct gaaggtccaa tagcgatagc cccgacattt
    55921 ccgatcattc cgatcactgc cccgccgata cctccaccga tacaagcagt aataaatggg
    55981 cgtcctagag gtaatgttac tccgtaaatc aatggttcgc cgattcctag gatcccgact
    56041 ggtaaagctc ctttgatcat ttctgttaat tctttatctt ttttgcagcg aatccataat
    56101 gccaatgctg cacccacttg tcctgcacca gccatcgcaa gaattggaag caatagcgta
    56161 cgaccagttt catcaatcat ttgcacatgg attggagtca aaatttgatg cagtccgaac
    56221 ataaccatcg gcaagaataa tgtgcctaga acgaagccgg caaatgctcc accaacgcca
    56281 agtacccagt tgatcccacc gaccatgcca tcagaaatga aacctgctaa aggcatgatg
    56341 aagaaaattt caatcagacc gatggcaatc aacgaaagag ttggtgtaac gatgatatct
    56401 accgcatcag gtactacttt atgcagtttt ttctcaacga ttgacaatag ccaaacagcg
    56461 aagatgacac ctaggatccc accttgtcca gctgcaagag cttcaccagt aaataagttt
    56521 ttcagtggtg cttccggatt catccctgtc agcatcacaa cggccccgat aactccacca
    56581 agagttggtg ttgcaccaaa aacttgtgca gcattgatac ctgtatagat aactaggtag
    56641 ctaaacatcc cgtttttcaa gatgttcatc acatcgatat attgttgcca tgttgctgca
    56701 tcaagtgttc cggctgtgac taagtttgct aaaactgcgg caatccctgc cacgatccca
    56761 gtaccgacaa atgcaggaat cattggcaca aagatattag aaatgtcttt taataccgat
    56821 ttgattttag atggtttttg tttcgatttt tgtgccgctt tcatttcttg tgcccgttcg
    56881 tttacacggt cttttccaga tgctgatgaa tttgctgtag ctgtacttac agaagaaagt
    56941 ttttctccta atttcacgcc tgccaaatca accatttgct gtgctacttt gttcactttc
    57001 ccaggtccga tgatgacttg aagctgttca tcttctacta caccaagcac tcctggaatc
    57061 gcttttaatt cagagacatt tacaagatca tcattgatga tcttcatacg cacacgagtc
    57121 atgcagtgga caatgctttc tacattgccc atgccgcctg cccctttata aatttgtttt
    57181 gccagttctt ccaaagtcag ttcgtttttt gccatggtct tttccccctc ataaggtccc
    57241 ttttacaaat ccgtttgctt cagctaattt tgcttgagct tcctctttat cactatttgt
    57301 caaaatcatg acgatagcca gcttaacatt ttgatctgct tcttcaaagt acttttcagc
    57361 tgtttcgtaa tcagcttctg tcgcttgcat gatgattcgt tttgagcgtt cgattagttt
    57421 ttcatttgtt ggtttgacat cgaccatcaa gttattgaat actttaccta taccaatcat
    57481 actgatagta gaaatcatat tcaagataag tttttgtgct gttcctgact tcaatcgagt
    57541 agagcctgtc aaaaattctg gacctgcatc gacttcgatt gggaaatccg cgtgtttact
    57601 gatttcggct tgtttattgc aagaaatcgt tcctgtgaca gcaccgatcg attttgcgta
    57661 atctaatcca ccgatcacat atggtgtacg accgctagct gcgataccaa taactatatc
    57721 attttttgtc aaattcagct tgattagatc ttcttgccct agctcataag aatcttcggc
    57781 cccttcgaca gctacagtca ttgcttcttc tccaccagca attagaccta tgaccatttc
    57841 cggttctaca ccgaatgtcg gtacgcattc agcagcatct aacacaccta gtcttccact
    57901 tgttccggct cccatataaa tcagacgtcc acctttttta aaggactcaa tcgtgttagc
    57961 aatcactggt tcgatacttg tcagttcttt ttcaaccgca gcggccactt tctgatcttc
    58021 tttgttcatt agttgaacgg cttgagaaat actcatctca tctaatccaa aagtttcttg
    58081 gtttctgcgt tccgttgtta ggttctctaa attgattttg ctcattttta tcttccttct
    58141 tttcttataa attgatagtt cataccagct ttgatttggt tgatcaatgg tagctcttct
    58201 ttgataactt tagctactac attcactttt tcatccgctg gcaaatcata tttggttaat
    58261 tggatctcac ccatatagcg caaatacttt tcgttatcta aagtaataga ccctttcata
    58321 cgcgtagctg tatttcttgc tgggataggc ggaatctctc gaaaacgtgc atctacgctt
    58381 cgtatgacat ctcttgcatc gtcttgccga ttcgtatgct tccctaatat atattcgtaa
    58441 aattcttcat ctacaggttc cgtatggagc aagactgtct gttctttttg gaaagaagca
    58501 aattgctcct gaacgttttc tgacagacct gcatctccga tgtaaacaat atccgtgtta
    58561 cttgctaata gatctagagc gcctgcaaga ggatggatcc ctcgatgttc ttccaaagtt
    58621 ggcaatcctt gatatagtgg gcctctcaac tctgtatctc ctggtacaaa accttggaca
    58681 aggagacctt gaattttgag ccattgattt tttttctgat accattcttt gtccagccct
    58741 gtttcgggac gtggataata attatgccaa gcttcaatct gtgagaaatc agcttctgct
    58801 tctttcaatt catcgatatc tttaggcgtg atcgtgctag cattcaaact gattttcaat
    58861 tgatgtgacc agtcggcaat ctgctgattg gaaatatgat aatccattct taaacctgtt
    58921 acaccaattg ctttcaaagg cgttagatct tctaatgaaa aacccgctcg ttccaatgcc
    58981 tctcctgaaa tatcgaccat caattctagt ttattctttt tcgcttcgct tcctagttcg
    59041 atcaatcgct tttgatatgc cgaaacatca tcttctggta tatgcatgga agtgaaaata
    59101 ccgacaaagc cattggatgc catttggcgg atatactgtt tcttctcttc tgacaaagaa
    59161 tcgttcataa atattgaaaa gccaaacata ttatccctct ttttctgtat ccgtcttcat
    59221 ttctatgact agagtatata tctaaagaaa caaaatttca atacttttat taaaataatt
    59281 aaatttcatt tctaaaggtt gagtttatat tatcaaaaga attgtcataa cctaaaaaag
    59341 gcactgctaa gcaaaagcag tgccttgaaa tattttattt aaataacaca aaaacataat
    59401 tactcataag aaaccaattc tgtattatct accatgaatg taaagaaccc ctcattaggc
    59461 atcggatgaa aataagcatt gatcactctt atcaaggcat tatggcaaac taacagatag
    59521 acattttctt cgtcttcgat gcattctttc aataaaggaa cgatccgtgc atacacatct
    59581 aagactgact ccccatttgg gaatcgtaca gcgaacgcta aacgtgcttt ttgaaagttc
    59641 tcatctttgc ttggcagtcc atcataatcc ccaaaatcca tttctaccaa tcgttcatca
    59701 acggtcagcg gcaagctgag acgatcagca actgcttgtg ctgtatctct tgctcgttga
    59761 agaggggaat ggatgatttt cgtgattgga acaggcaaat ctactacctt ttctgctagt
    59821 ttctgtgcct gcatctgtcc tttttcagtc agcggcacat ctgcccgtcc gcaaactaat
    59881 ccttgtgcgt tccaagttgt ttctccgtgt ctcgttacat aaagcatgtg attctctcct
    59941 tcgttggcaa agttcccctt aaccatacct tgttgttctt gagattacaa gggttagatt
    60001 ctctcaagag aaataatctc agtagatact ttatccagga aggtttgatc atgttccact
    60061 agtaacatgg caggtttcac gttcaagatc agttgttcta attgttcttg attgaagaca
    60121 tccaaataat tcaatggttc atcccatgta tatagttcag ctggctgtga taaagattta
    60181 gccaattcca cttttttccg ttggcccata ctcatctgct cgatcttgtt atgaaaaaca
    60241 tctctttcca tcccaagctt tcggaggttg ttcaaaaatg cttggtagtc tacttggttt
    60301 ttctctgcaa attccgccaa cgttcctcga ttgtcttcat aattttggct tgcataacta
    60361 atgctcagat gttttggctg gtatttttct cctataacct tgccgttgaa tgcccccaga
    60421 agataatgga taatggatga ctttcctgca ccgttaggac ctgaaatcgc cacccgctga
    60481 tgaggctcga ttgtaaaatg aattggctcg aataacagat tttcataccc taattgaaga
    60541 tcttctacgc ttaaaagtcg cttatggtga gacgcttggc tattcatcgt caaagaatcg
    60601 atatattcga tatcttttaa tagtttttct ttctcgctga tctgggtctc catccgattc
    60661 acgattgctt tggatcgttt catcgtccgt gcagcatcag cacccactgc tcctttattc
    60721 actcgtctag attcagtatc gatgaatccg acttgtttct ttgttttatc tccttctcgg
    60781 gaacgagacc attcggcttt ttcagctgct gttttcttta gcctactgac ttcttttttc
    60841 aatttttcat tttgagccat ttcaaattca tcacgaagtt ttttctgttc ttcatagata
    60901 gagaaattcc cttgataaag ttccagttga cttttttcga ttgctaaaac atggtccact
    60961 acttcatcga taaatccccg gtcatggctg accacgatga agccttgttt tttctttttc
    61021 aaataagccg ctacttgttt tctaccagag atatccaaat gattcgttgg ttcatcgatt
    61081 aacgggaaat gagtgtcatc cacaaataaa agtgccagta ggacttttgt cttctctccc
    61141 cccgatagtg tgctgaattc tctccataag atttcaggat ctgtttgcat caattggagc
    61201 tctctttcga tttcccatat ctcaaaatcc gtaatatcat ttaacacgta ataggttaaa
    61261 cgttctttat cttttgtctg ttgcgggaaa taggcaaatt cttgctgatg gattacttgc
    61321 ccttgataag gtagtttgtt ttgtagaata ttcagtaaag ttgtctttcc tcgaccgttt
    61381 cgtccgataa gtcctagttt ccattgtgtg tcaaaattta gatttgcttg ttcaaataat
    61441 aatgtgcctt ggctgtcgta gccgaatgtc agatttttta tttcgatttt agacattttc
    61501 catcacctcg taaaaaaaga ccagtcctat tttcagaact ggctaaagag gatgcaaggg
    61561 ttggatacac acaaaaagac ccatacatcg aaaaaaccaa gccaatcccg aaaatctgca
    61621 cactgcttcc ttgtctccac aaggtacagt ctgaatgcag ctttcatcaa tcgacttaat
    61681 ttttcaatgc acggatccct cactttgtcc tatatttgaa attacgatag cataaagaaa
    61741 atgattttgt caactacttc gggaggatgg tgaaaaatct gctaagtgtc tgtcctaaga
    61801 tttttgtttt ttctaatgtt tgcctgtgtt ccattgcttc ttctaaacct attggaccca
    61861 aatgaatact taagacaatt gggagaaaat cagaaagtcc ttctagctct tggtctctac
    61921 ttccgcaaat agcgattatt ggttttcgat atttttttgc aagcactgct acaccgtatg
    61981 gaacttttcc gtggatcgtt tgctgatcga tccgcccttc tcctgtaatg atgacatctg
    62041 cttgttcgat ctttttttcc aatccagtga tttggctgac taaatcgaaa ccagaaacca
    62101 tcttcgctcc caacaaaaaa agggctccac caataccgcc tgctgctcca cttcctggaa
    62161 tatcatctaa atccacctcc cagaaatctt ttatttgctg agcaatcttt cctgcttgtt
    62221 tatctaagaa agctagcgtc gtatctattc ctcctttttg tcttccaaat tgccaagcag
    62281 ctccttgttg acctgtatat ggattggtaa catctgcagc gataatcaat tttactttag
    62341 aaacaagaac gtttcttcga tcaaaatgaa gttttttagt agataataaa ggatttcctt
    62401 ctgtgtaccc ttctaaagaa gcacccaagg attggagtaa tcctagacca ccatcgctac
    62461 acccgcttcc tcctaaagtg acaataattt gttctacttc ttgaagcagt gcatctttaa
    62521 taagttctcc taaggcataa ctggaagcaa gtcggatagt ttgatccgtt ggtttatcaa
    62581 gtagatctaa ccccaatgct tgtgcagatt cgatgactgc ggtgtttttt ccttgccaag
    62641 ttgtcaataa atagctgatt tttcgctgac ggaataagag atccatccca tcaatggtac
    62701 gccatgttcc cctgagcgcg taatagattg cttctgcagt attttctccg ccatctgcaa
    62761 tcggcacatt gatttttctt cctttacgat cttcccagcc atttagaact gcctgattta
    62821 gttcaaatga agaagcactt cctttaaatg aatcaattgc cgccaaaata tccatctgta
    62881 tccctcactt tcttcttaag taagacactt tttttcattt ttttcaaaca aaacaatgct
    62941 attttcttcc atttttctat atactaaaag ggaactcatt gaataaagga gagaaaaaac
    63001 atgaaaatcg caatagctgg ggccggagca atgggcagcc gaatcggatt gatgctacat
    63061 caaagcggaa atgaggtcct cttgatcgat cgttggcctg ctcacattga agccattcgt
    63121 acaaatgggt tgattgctga ctttaacggt aaagaagtgg tcgcaaaact gccaatctat
    63181 tcaccagaag aaatcatcga aagcaacgaa cacgtggact tgatcgtagc attaacaaaa
    63241 gccaatcaat tagatgatat gttttgttcg atccaatcca ttattactga caatacttat
    63301 gttttgtgtt tactaaatgg attaggtcat gaagatgtac tggaaaaata tgtgccaaag
    63361 aaaaatatct tatttgggat cacgatgtgg acagctggtc tagctggtcc cggaaaagtc
    63421 acattgttag gtgatggaga aatcgaacta gagaacttgg aaccagaagg cgaagcattt
    63481 acaaaaaaag ttgtagaagt ctttcaagaa gcaaatttaa atccgatcta tagccataac
    63541 gttcgttatt ccatttggcg aaaagcttgt gtaaatggaa cattgaatgg tttatgcacg
    63601 attttggatt gtaatattgc tgaactaggc gcgcaaaaag cggcagagag catggttcga
    63661 acaatcgtat ctgaatttgc ttctatcgca gcaaaagaag gaatcatact agatcaagaa
    63721 gaagtgtacc aacatattgc ttctacttat gatcctgaca acatcgggtt gcattaccca
    63781 tctatgtacc aagacctgat caaaaaccat cgtttgactg aaatcgacta catcaatggt
    63841 gccatttggc gaaaaggaca aaaatatgat attgctacac catattgtgc ctttttgacc
    63901 caattagtcc atgcaaaaga aggaatcctt ggcgcagaat aaaaggctct ctgatgagaa
    63961 tcagctgaat cagcagctgg ttctcttttt ttaagcccaa taaaagatca aaaagaaaac
    64021 acaactctca tgatgccata agaattgtgc ttgtttgttt cagtacataa tctcttcaaa
    64081 atgtaggttt tttatttgtt ttcaacagag gagaggtcat attcgtattg ctcataaata
    64141 gtggaatcgt tagtgataaa tcgttttgcc caattttctg catcataaaa ttccaatagc
    64201 tctgatagga ttggcttaaa tggtgtatgc agaaattccg gtaattcatc taaatcacgt
    64261 tctcgaagca aaaaaatatt ttcaggacga taaaaatgat aatgagcaat cgcttgatta
    64321 tccgtcacta gtttcttttg aaaatacatg gattcaaatg tccgcaaagt cactccttgc
    64381 tgaccctccc gcaacagttc cagaatcccg cgcgattccc ctgttttttt caggtactct
    64441 tcataagtaa gatatccagg ttgttcattc cctcgatgtg gaagaatgaa atagttggtc
    64501 gtaacatctc tttttataaa ttcctgctta tagctttctg ctcgttcttt tctcccatta
    64561 ttcgttgcac caaaaaatag atccgtcttt ggttcgctag aagaaaaatt catatgtttc
    64621 gaataaaatg aactattatg tttcagccca agttcttttg cttccaaaaa atcaaaatga
    64681 taaatctcat cgattgccgg ttcatcttgt gcctgcttca gcatcgcctc gtgttctgct
    64741 ttgaagtgat tccaaaaaaa taacacaatt tttgcattgg taaatgggcg cacgcgtcga
    64801 gccatctcca tatcaaatcc ataatctaaa aaaacgatca gctgataatt tgccaactgt
    64861 tgtctagctg atttaatgaa ttccgactgt agtaaatctt ttccggacca aacatctaaa
    64921 gagcggatgg aaggcaaaaa ataaagtgat ttattttttg caactagcag tacgtcattt
    64981 ttgttcatct tttccgcctc actttctctg tcactttttc ctatgatagc ctgtttaaat
    65041 agtaaaaagc cagtaaaacg tttcctatat ttgtatgaaa atttaacatt tgtatgaaaa
    65101 tatgatgaaa taaatcattc ttctattaaa attcgcctaa aagttttctg aatagttgta
    65161 attgtctgaa aatttgttat cattagtcat tgttaaatat tgctatttat tcttaatata
    65221 aattttgatt gtgaatttaa aagaaagagg tcatttatgg aagataaaaa attgaaaaaa
    65281 caacttagct ccagacatat caccatgtta gctttaggtg gagcaatcgg tgcaggtcta
    65341 tttaaaggaa gtggcgaagc gattgggatc gccggccctt ctgtattgat tgcttttttg
    65401 attggtgggc tgattttata tatcgtgatg aaaggtctgg gaaaaatcgt tttaagcggt
    65461 ggcgacacgc atcacggatt atctggtttg atacgccctt atctaggtgc tcattctgct
    65521 gattttactg attgggtcta ctggtctatg tggattatca atatcatcgc tgaagctgtt
    65581 gcagctgctt cctttttgca gttgtggttc ccgcacattc cagcctgggt atttgttttt
    65641 atgttggctg ttttaactac gatcatcaat ctttattcgg tacggttatt cgcagaaaca
    65701 gaatattggc tggcttttgc taaaatcagt gtcattatct tactgatcat ttttgctact
    65761 tatcttgtcg gtcagcaaat gttgggcaca ggcgttttcc ctacccttca gcaattgact
    65821 gaccatggtg ggtttactcc tcatggtatg aagggaatca tcagttcttt gcttgtagtt
    65881 atctattctt acggcggttc tgaactgatt gctatcacgg taagcgaagc agatgatcct
    65941 aaacgtgcga ttcctaaagc aatcaaaggt gtcatgggaa gaatcatttc cttttacatc
    66001 attcctttgt ttttgctttt gattcttttt ccttggaata ctttagcagg cacgaatgtc
    66061 agtccttttg tgatggtatt tgaaaaaatg aatatcccat ttgcagcgga tatcgtcaat
    66121 tttgtgattg tccttgcttt gttctcatct atcaattcgg gtgtgtatgc atcttcaaga
    66181 attttgttct tccgtttgaa ggatcgaaaa ggttcctcta gaaaactagc tgttttaaac
    66241 aagcatcaag taccgcaacg tgctgtttta ttttgtacca gtgttcttta tcttggtgta
    66301 gctctttctt attttgtcgg tgacaaatta tttggctatc tggcaggttc cctttcgtat
    66361 acagtattat tgatctggat cattatcagt gcggcatcct ttgtactggc actaagaaaa
    66421 ggaacattat gggataaagg aatcagcttt tttgcattag ctgtcttagg attgattttc
    66481 cttggtatcc tgttcacgaa ctccattggg gtaactgtat tgactggcct gctttacctg
    66541 ttcatttatt tcagttatca aaaaaagaat gatgcgttcg tattgacgaa tgaatgaaat
    66601 cgatagaaaa ttttatttta tttatgtgga atagatggag ctattgaaga aaggagttgt
    66661 gacaaaagtc ttgttgcaac tcctttttcc gaataaacag tctcatgacc tcttggtaaa
    66721 cggtgttcaa aaaccctctg tgcaaaataa ttgattgttc tccatgctca tgacatgata
    66781 gaagaaagga atgaaaaaaa ggagtttgtt ttaaatgaaa aagtattgga agtttttgtt
    66841 gatgatcggt gtttcaacgg tagttatgtt tggtatgatg tacttgaatg tctatgcgct
    66901 cgatcatatc ttcttcagtc gtacacgagt attcatggcg ttgatgatgg gtgcagtcat
    66961 ggcagtcatc atgctgttgt tcatgtggaa aatgtatgaa aacaaaaaga taaatgttat
    67021 gatcttagcc gctagtcttc ttgtttttgc cggttccttg tttatggtac gaagccaaac
    67081 tactgtcaac gacacagctt ggatgaaggc catgattcct catcattcta tcgctatcct
    67141 ggcaagtaaa cgagctgatt taaaagatcc tgaagtaaaa aaattagcgg aagaaatcat
    67201 tcaggcacaa gaagaagaga tcgacaaaat gaaaaaaatg atcaaagaaa tggaatgacc
    67261 attatccgtc caaataaaaa aagaggatgt tccagaagtt atcagcttca agaaataaga
    67321 agaagctact tctggaacgc cgtgaataag gggttgtgaa aaagctgccc tgcatcaagt
    67381 aataagaaca gccaaacaaa aatagcttct cctatttttc gtttggttag gcttattacc
    67441 gcagatgcaa gcttttgaac accgtttatt aagaggttgt aaaatcagcg ttctgacctg
    67501 agtattagag agacaaatgg aaaaatagtt cctcatattt tgccattttt tgagctaata
    67561 ccgagggtca gctgattgaa caccgtttat cgagaggttg tgaaaaagtc gcttagtttc
    67621 gcgtattaag aaaaattttg tgaaatggct ttccacattt ttgtataaat ttggcttaat
    67681 accgagaaac tggcttttga ataccgttta ttcgtaaaag ggattgtgac aaaagtcttg
    67741 tcacaatccc tttttatgtt tt
//
LOCUS       DAFEML010000008        62825 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFEML010000008
VERSION     DAFEML010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.008"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..551
                     /locus_tag="LP468_000624"
     CDS             <1..551
                     /locus_tag="LP468_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080186.1"
                     /translation="AILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENTHGV
                     PAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKLVFK
                     DDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILIVSY
                     LIVLVIPFTIYACRHKFQHAEK"
     gene            574..1500
                     /gene="glsA"
                     /locus_tag="LP468_000625"
     CDS             574..1500
                     /gene="glsA"
                     /locus_tag="LP468_000625"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL2080187.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            1708..3168
                     /locus_tag="LP468_000626"
     CDS             1708..3168
                     /locus_tag="LP468_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080188.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            3389..5152
                     /locus_tag="LP468_000627"
     CDS             3389..5152
                     /locus_tag="LP468_000627"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL2080189.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            5236..5694
                     /locus_tag="LP468_000628"
     CDS             5236..5694
                     /locus_tag="LP468_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL2080190.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            5803..6486
                     /locus_tag="LP468_000629"
     CDS             5803..6486
                     /locus_tag="LP468_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2080191.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            6633..7247
                     /locus_tag="LP468_000630"
     CDS             6633..7247
                     /locus_tag="LP468_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL2080192.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            7263..7469
                     /locus_tag="LP468_000631"
     CDS             7263..7469
                     /locus_tag="LP468_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080193.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            8010..9140
                     /locus_tag="LP468_000632"
     CDS             8010..9140
                     /locus_tag="LP468_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2080194.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            9232..9987
                     /locus_tag="LP468_000633"
     CDS             9232..9987
                     /locus_tag="LP468_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2080195.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            10045..12084
                     /locus_tag="LP468_000634"
     CDS             10045..12084
                     /locus_tag="LP468_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL2080196.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(12193..13344)
                     /locus_tag="LP468_000635"
     CDS             complement(12193..13344)
                     /locus_tag="LP468_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL2080197.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(13498..14028)
                     /locus_tag="LP468_000636"
     CDS             complement(13498..14028)
                     /locus_tag="LP468_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2080198.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(14127..14477)
                     /locus_tag="LP468_000637"
     CDS             complement(14127..14477)
                     /locus_tag="LP468_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL2080199.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(14634..16163)
                     /gene="ahpF"
                     /locus_tag="LP468_000638"
     CDS             complement(14634..16163)
                     /gene="ahpF"
                     /locus_tag="LP468_000638"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL2080200.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(16173..16736)
                     /gene="ahpC"
                     /locus_tag="LP468_000639"
     CDS             complement(16173..16736)
                     /gene="ahpC"
                     /locus_tag="LP468_000639"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL2080201.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(16880..17542)
                     /locus_tag="LP468_000640"
     CDS             complement(16880..17542)
                     /locus_tag="LP468_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2080202.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            17726..19372
                     /locus_tag="LP468_000641"
     CDS             17726..19372
                     /locus_tag="LP468_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL2080203.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            19363..20445
                     /gene="uxuA"
                     /locus_tag="LP468_000642"
     CDS             19363..20445
                     /gene="uxuA"
                     /locus_tag="LP468_000642"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2080204.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(20553..22106)
                     /locus_tag="LP468_000643"
                     /pseudo
     CDS             complement(20553..22106)
                     /locus_tag="LP468_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            22254..23395
                     /locus_tag="LP468_000644"
                     /pseudo
     CDS             22254..23395
                     /locus_tag="LP468_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(23521..24600)
                     /locus_tag="LP468_000645"
     CDS             complement(23521..24600)
                     /locus_tag="LP468_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2080205.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(24703..25143)
                     /locus_tag="LP468_000646"
     CDS             complement(24703..25143)
                     /locus_tag="LP468_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2080206.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(25200..25610)
                     /locus_tag="LP468_000647"
     CDS             complement(25200..25610)
                     /locus_tag="LP468_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2080207.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(25790..26224)
                     /locus_tag="LP468_000648"
     CDS             complement(25790..26224)
                     /locus_tag="LP468_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2080208.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(26324..27172)
                     /locus_tag="LP468_000649"
     CDS             complement(26324..27172)
                     /locus_tag="LP468_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2080209.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            27561..29327
                     /locus_tag="LP468_000650"
     CDS             27561..29327
                     /locus_tag="LP468_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL2080210.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            29429..30688
                     /locus_tag="LP468_000651"
     CDS             29429..30688
                     /locus_tag="LP468_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2080211.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            30835..32136
                     /locus_tag="LP468_000652"
     CDS             30835..32136
                     /locus_tag="LP468_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080212.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            32139..32990
                     /locus_tag="LP468_000653"
     CDS             32139..32990
                     /locus_tag="LP468_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080213.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            33003..33818
                     /locus_tag="LP468_000654"
     CDS             33003..33818
                     /locus_tag="LP468_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL2080214.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            33969..35135
                     /locus_tag="LP468_000655"
     CDS             33969..35135
                     /locus_tag="LP468_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2080215.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            35365..36012
                     /locus_tag="LP468_000656"
     CDS             35365..36012
                     /locus_tag="LP468_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2080216.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            36096..37040
                     /locus_tag="LP468_000657"
     CDS             36096..37040
                     /locus_tag="LP468_000657"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL2080217.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            37175..38626
                     /locus_tag="LP468_000658"
     CDS             37175..38626
                     /locus_tag="LP468_000658"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL2080218.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            38647..39483
                     /locus_tag="LP468_000659"
     CDS             38647..39483
                     /locus_tag="LP468_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2080219.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            39483..40139
                     /locus_tag="LP468_000660"
                     /pseudo
     CDS             39483..40139
                     /locus_tag="LP468_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            40212..40901
                     /locus_tag="LP468_000661"
     CDS             40212..40901
                     /locus_tag="LP468_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080220.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            40907..41863
                     /locus_tag="LP468_000662"
     CDS             40907..41863
                     /locus_tag="LP468_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL2080221.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            41907..42419
                     /locus_tag="LP468_000663"
     CDS             41907..42419
                     /locus_tag="LP468_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080222.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(42675..43223)
                     /locus_tag="LP468_000664"
     CDS             complement(42675..43223)
                     /locus_tag="LP468_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2080223.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(43312..44493)
                     /locus_tag="LP468_000665"
     CDS             complement(43312..44493)
                     /locus_tag="LP468_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL2080224.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(44729..46237)
                     /locus_tag="LP468_000666"
     CDS             complement(44729..46237)
                     /locus_tag="LP468_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL2080225.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            46396..46587
                     /locus_tag="LP468_000667"
     CDS             46396..46587
                     /locus_tag="LP468_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080226.1"
                     /translation="MKKRQKKENAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            46790..47707
                     /locus_tag="LP468_000668"
     CDS             46790..47707
                     /locus_tag="LP468_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL2080227.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            47700..48773
                     /locus_tag="LP468_000669"
     CDS             47700..48773
                     /locus_tag="LP468_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080228.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            48921..49439
                     /locus_tag="LP468_000670"
     CDS             48921..49439
                     /locus_tag="LP468_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080229.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            49420..49812
                     /locus_tag="LP468_000671"
     CDS             49420..49812
                     /locus_tag="LP468_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL2080230.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            49888..50823
                     /locus_tag="LP468_000672"
     CDS             49888..50823
                     /locus_tag="LP468_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL2080231.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            50956..51735
                     /locus_tag="LP468_000673"
     CDS             50956..51735
                     /locus_tag="LP468_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2080232.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            51728..52045
                     /locus_tag="LP468_000674"
     CDS             51728..52045
                     /locus_tag="LP468_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2080233.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            52289..53899
                     /locus_tag="LP468_000675"
     CDS             52289..53899
                     /locus_tag="LP468_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2080234.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            54056..54904
                     /locus_tag="LP468_000676"
     CDS             54056..54904
                     /locus_tag="LP468_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2080235.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            55135..55614
                     /locus_tag="LP468_000677"
     CDS             55135..55614
                     /locus_tag="LP468_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080236.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            55647..57875
                     /locus_tag="LP468_000678"
     CDS             55647..57875
                     /locus_tag="LP468_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2080237.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            58004..59647
                     /locus_tag="LP468_000679"
     CDS             58004..59647
                     /locus_tag="LP468_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2080238.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(59720..60265)
                     /locus_tag="LP468_000680"
     CDS             complement(59720..60265)
                     /locus_tag="LP468_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL2080239.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(60288..60773)
                     /locus_tag="LP468_000681"
     CDS             complement(60288..60773)
                     /locus_tag="LP468_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2080240.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(60763..61575)
                     /locus_tag="LP468_000682"
     CDS             complement(60763..61575)
                     /locus_tag="LP468_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL2080241.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(61714..>62825)
                     /locus_tag="LP468_000683"
     CDS             complement(61714..>62825)
                     /locus_tag="LP468_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL2080242.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        20934 a        11234 c        12241 g        18416 t
ORIGIN      
        1 ttgcgattct tgtttgttta ggtgtcatcg gagaaattgc ttcttgggta acctctcctt
       61 caaaagcact tcacgtagca gcagaagaag gattacttcc tgaatatttt gcaaaagaaa
      121 acacacacgg tgttcctgct catttgatga tcgcaaatgg gatcgttgca acaatctggg
      181 cagccgtctt tacattaagc ggcgggggga ataatctttc atttcttgca gcgatgtcat
      241 tgactgttgt aatctacctg atgttgtact ttatgttttt cgcgggctat ttgaagctgg
      301 tttttaaaga tgacagtctt gaaagagcct atcaggttcc aggcggaaaa gttgtaaaag
      361 taatcgttgc ttgtttaggt cttttgactt cactttttgc tttttgtatc tcatttgttc
      421 cacctgctag tatcgcagct ggacagcatg ggatttatga aacgattctg attgtttctt
      481 atcttatcgt cttagttatt ccatttacga tctacgcatg ccgtcataaa ttccagcatg
      541 cagaaaaata aaaaatgaaa gctggttatt caaatggaag taaaagaatt agaacaattg
      601 attggaaaaa atttccacta ttatcaaaca ggacaagtgg cggattacat tccagcatta
      661 gctgaagtgg atcccaaaca attaggtatg gcgatttatg atttggatac aaaacaactg
      721 attgagggag gagacgccga tgtgcgcttt gccatcgaaa gcatgtcaaa agttcccgta
      781 ttgttattag caatcaaaga caacggaata gaaaaagtct ttcaaacaat caacacggaa
      841 ccaaccggtt ttgccttcaa ttctatcatg aatatggaaa tcaatcatcg caaacatcca
      901 atgaatcctt ttgttaatgc aggagcgatt gcaacaacct cgttgattgc cggtaaagat
      961 gcagatgaaa aatttgagcg aatcttgtca tttatgaaag agatctgtga tgatcctaat
     1021 atcacattga atgaagaaat ctatcattct gaatcaagaa caggtgatat caatcgctct
     1081 cttgcttact atatgaaagg taatcaaatg atcgaaggag acgtaccgga gatactcgat
     1141 gcttatttca gacaatgctc cctcaatgtc accgctacag gcatagcaaa attagctgct
     1201 gtgctggcaa ataaaggaat tgctccttgg aatggcaaac aaatcattac tgaagaaagt
     1261 gctacaatcg tcaaatcaat tatgacaact gctggtttgt atgatgaatc aggagagttt
     1321 tccgtccatg ttggtgtacc tgcaaaaagc ggtgtaggcg gcgggttgat ggcagctgtg
     1381 ccaaatcgtt acggcatagg tgtcttcagc ccggcactag atccatttgg taacagcgca
     1441 gctggtatcc aattgttgaa agatgtagtc aaagaactag acgctgacat ctttgaataa
     1501 ccattcttga aagaggctgg ggtaaaagtc caaacggctc aaagctacct acaatgaggc
     1561 tgaaattgtg agcttgtttg acttttgtcc cagtttcttt ttttattggt ttttgaaagg
     1621 gcttttctaa ataaaaagga aacaaaaata cgatttacag atatgattaa ataaaatcat
     1681 aagaaaaact ggaggcgtgt atcaggaatg ctggaaaatt acatcgagcg aaatatattt
     1741 agaaaagtgt atctgtgtga acaattattt gaattccaag aaatagacat cgaacaaaca
     1801 gctatttctc taagggtgac tacaccaacg atccttcacg atctagaaag tctagccgag
     1861 tgtctagaat attgtataaa agaacaagta agagagaagc ataagtataa actcgtattc
     1921 aaacatggta ttgctctttc tgagctcaca cagtttctgt acggtcaatc ttatttttta
     1981 aagtttttaa gttattattt taatggtata ttcacgagta cagaactggc tgatcttgaa
     2041 tttatttctt tgagtaaagt atatacaatc aaaaaaatcg tattggattt ttttaaagaa
     2101 aatgattatt tgaaaaataa agaaatcatt atcccagaat ttgactcgcg gaacatcttg
     2161 ctagctttag tacgttatgt caattgggaa ggctatgaaa ataaaaatcc gtatgtagaa
     2221 gaagcttgta acgagttgat tgattatgta gagactcatt tttttaaaag aagatattcg
     2281 gaagatgaaa agtcctttat catacgagaa atagagatcg caatcggaag aaaggcattt
     2341 ccccttggac tgaaagaaga agataagaaa agcgcagaaa cgaagccgtt atttcaatta
     2401 gtctgtcaag gattggaaga gcaaaaagga attctagact tacaagaaga agatgtctat
     2461 tatatttttt ctttgttcaa cagtagaaat tataccaatg agaacatgga gctgttaaga
     2521 aaagatttcg aagttgttta taaaaatttt gttctcaatg acctatcact gaatgaattg
     2581 attttacaga ttattagtat cgctgaaatc gacgatgcag aaaattttat tttcaagcaa
     2641 tcctttttac aatttgtccg tacgttgtgg gcagatggac aagtattttt accggaaagg
     2701 atctatcttc tatcagaaaa agaacaactt ctgtacggaa aaattgtaga aatattggaa
     2761 gagtggaaaa agaaaaatca aatccaacta agatggaatg aaaatttcat tcgaaaattc
     2821 gtcaaaagtc tttctttgat caacagtgaa caagcgggga gacaggaaat agaaattttt
     2881 gttgtttcag aaagttcagt caaacaattt ttttatcgaa cccaatttca tttgtatgcg
     2941 gaagaaggca tcgctgaaat aaatcctatt ttatttcgtt cattagaaga attgcctgat
     3001 gaatgtctat gtgcgaaaaa aagagtggtt ttgtgcgatg ctgctagcta tcaaaatgga
     3061 ttagaaactg aaaagacaaa gatctatcca atctcattaa aaggtgcaaa catccatttg
     3121 tatcatattg ctcaggaact tcacctatta aaaaaacata tttcttgatg agaccttaat
     3181 taggagacct tctacaaagc tttttaattg tctgtagaag gtttttattt gagtcctgat
     3241 tcgtgcgaag atctacttat ataacaagct ttctctgaaa tttttttaaa atgctattga
     3301 cttagagtca actctaagta gtagaataga taaagtgtaa caaatctatt ttcattaaaa
     3361 gaagatagta cggaggagag aatgtattat gagtacagta ttacatgtat tggatgcaat
     3421 caatagcccc gcagatgtca aaaaattatc tgttgaggaa atgaaacagt tggcagaaga
     3481 gatgcgccaa aaaatcttgc aaaaggacag cgatgtaggt gggcacgttg gtccgaatct
     3541 aggtgtagta gaattaacga ttgcgtttca ttatgtattt gattcaccaa aggataaaat
     3601 cgtttgggat gtttcccatc agtcttatgg tcataagctt ttaactggtc gaaaaaatgg
     3661 ttttgaaaaa ggacattacc gtgaagtgag cggatattcc aaccaacatg aaagtaaaca
     3721 tgactatttt acagtggggc acacatctac atctatcagc ttagcaacag gtttagctaa
     3781 agcgagagat ctgaagaaag aatcaggaaa tgtggtagca tttatcggtg acggctccct
     3841 aagtggtggc ttagcttttg aaggattgaa caatggtggt gttttacaat ccaatctaat
     3901 cgtattagta aacgataatg agatgtctat tgatgagaat catggcagtt tatataaaaa
     3961 cttagctgag cttcgtcaaa ccaacggtaa aagcagcaat aacctattta aagcaatggg
     4021 atttgattat cgttacgtgg ataatggaaa cgatctggaa acggtgatcc gtttatttga
     4081 agaagtaaaa gatattgatc atccgattgt acttcacgtc catacggaaa aaggtcgcgg
     4141 ttatcagccg gcaatcgata ataaaatgaa atatcattgg catgtaccat ttgatctgtc
     4201 caccggggag gcaaagcaag taacttctgg agaaacattt aatatgatca tcatggatta
     4261 tttggataag aaaatgcaaa caagtacagc tcctattgcc gcagtcaatg cagcgatacc
     4321 aggcgccttt ggactgaaaa cattccaaga aaaacatcca gatcattatt ttgacgtggg
     4381 gatcgctgaa cagcactcta tcactttcgc ttctgctttg gcttctcagg gagtacgtcc
     4441 agtcgtcttc caatcaagta ctttcttgca acgggcatat gatcaattat cacatgattt
     4501 agcgatcaac gagaatccag tgattatttt agtcggtggc ggaacgatct cagctagtga
     4561 ccgaacacac caaggaacat ttgacattcc ttacttatca agtatcccga acatcaaata
     4621 tcttgctcca gcaacaaaag aggatatgat ctctatgcta gattgggcgt tcgaacaaac
     4681 agcgcagcct gtagcaatcc gaattcctac acatggtgta gaacatggta cagctatcgc
     4741 aaatgattat agtattccag cctatcaaac agtaaataat ggaggaaaag tagcaatttt
     4801 agctttaggc ggttttcttg aattaggaaa agaaacagta aaagctttta gaaaaaaagg
     4861 aatcgaagca acgttgatca atccaggaac gatcacagaa aatgacgtag aaacattaga
     4921 taaattaaaa gaaacacacg aattagtcat cacattagaa gatggtagtt tgtcaggagg
     4981 atttggcgaa aatatcagtc gttattatgg tgattcttca atgaacgtat taaattttgg
     5041 tgcagagaaa gaattcacgg atagcgttcc tgtagggcag ctttatgaac gttatcattt
     5101 aacaccaaaa caaatcgttg aagatagtct gcgtgtcttg aatattcaat aattcattat
     5161 gctcaccatc cagataattg tttatactag tatctggatg gttttttcat tataaaaagc
     5221 aaaggggtgg atgttatgta tcagcaagta gaagaatatg tcaaaaagtt ccaagaaaaa
     5281 tatcctagtt atcaatcaga aaaattaggt ttcttttcat ttggggatac agaaaaaatg
     5341 gcagacgagt tgagcgaact agttgtaaaa aagataaaga ctggtacatc aagtggttac
     5401 gatctgtata aacaagagaa tgagccttta ccaaaagttg gtcaattaga cgtggtcctg
     5461 aatggaaaaa atgaaccagt ttgtatcatc aaaaatataa atgtgaccat cttgcctttt
     5521 agtgaagtca cgaaagagca tgcttggaaa gaaggagaag gggatcggac attagcttat
     5581 tggcggaaag tccatgctga gttttttaaa catgcttata aagaagcgtt gaacatagaa
     5641 tttacagaag agaagctggt cgtatacgaa gaatttgaag taattttctt ttagtaagaa
     5701 aggtctgctg aaagaaatag ctcattattg tctcctgaat agaaaagggt tacattttta
     5761 tatgaagctg tatttttata taacattact ggaggagata ttgtggatac actggaacaa
     5821 atcaaaggcg gagtcgtcgt ttcttgtcaa gctttggaaa acgagccgct acacagttct
     5881 tttattatgg ggagaatggc tttggctgca aaagaaggcg gagcagttgg tattcgagca
     5941 aatacgacag aagatatcaa tgaaatcaag cgaatcgttg atttaccggt aatagggatt
     6001 atcaaaagag attacgatgg gtcagaagtg tttattactg cgacagaaaa agaagtggaa
     6061 gaacttttgg agacgcaagc agaaatcatt gcactggatg caacttctcg taaacgtccg
     6121 acagaaaaaa caactgctga acttgtccaa atgattcacg aacacggtcg gttagctatg
     6181 gcagatattt cgacttttga ggaagcgctt caagcgcaag aagatggttt tgatcttttg
     6241 tctacgactt tagcaggcta tacagaatat tcacgaaaga cgcagacacc tgattttgat
     6301 ttattgaatc aaatcataga acaagtcgat atcccagtaa ttatggaagg acatactgac
     6361 tctcctgaac aagtagagaa agcatatgaa ttaggtgctt tttcagtcgt agttggatct
     6421 attatcaccc gtccgcaatt gatcactaaa agatatgtcg aagccgcaag taaagcaaat
     6481 aactaaaaaa cacgcacggc acagattctt gacaaaaaag aaaaattgat agatagttta
     6541 aagcagattc taagaagatg aaaaaagcat tacttttcat tttgtcttca agatctgctt
     6601 tttaacgaat tttatagaaa gaaggcgaaa ccatgtttga acggagtcct tcagaattga
     6661 cagaacgtga aaattacaag ttgctgattg gttcagtcat ccctagacca gtagcagtag
     6721 taacgactaa atcagcaaaa gatatagtga atatcgcacc cttcagttac ttcaatatcg
     6781 tcagttcgaa tcgacccatc ttatccttgg cgatccagag aaaacaagat gcagtaaaag
     6841 acacagcaaa gaatattctt gagacaagag aagctgttat ccatatcctt gatgaggaca
     6901 acgtagaaga agtaaataaa acagcagcca atctgcctaa tgaggaaagc gaactgtacc
     6961 tgactgactt gactttaact gattcagtaa tcatttcagt accagcattg acagaagcaa
     7021 aagttcgttt tgaaacatcc ttatatgaac atgtcgagat acggaataaa aataaagtaa
     7081 cagctgattt atttttgcta gaagtacaga aatatcattt aaatgaaaca gtctatgatg
     7141 ataagacagg aaggatcgat ccaagaaaat tgaatgctgt aagccgtttg gcaggaaatg
     7201 attatgcagc aataggagaa attttcacga ttgcacgtcc cgaataaaaa ggagcactag
     7261 ttatgttaaa aataagctat aaaccatcga cagattcaaa agaaatgaaa aaagaatatg
     7321 aaacagtgaa tgattttctg caagggcagt acttagaagt tccgccattg caagaccatt
     7381 ttgtcgttac tactgttact ttagatggta aggaaataga aatgccagat caaacgatta
     7441 gcggattgtt taattacttt aacaaataaa tatttattcc gaaaagtgaa aaaacatata
     7501 aaaaaacaca taaaactaaa aaattatcaa agaatcctgg tgcaactgaa agaatttgca
     7561 acgggattct ttcaacttat ttgttatttt tttctaaaaa atattaaaga ttgttaaatt
     7621 tcactatttc atttcaaatt ccattgccta atcattagga aaagtctatc atgaactcgt
     7681 aaatagaata tagtaataac cttgttaggt gaggctccta tacaaacata ggctgttgcc
     7741 cagaaacgtc gaaagtcgcc aatgggtaaa acagaaactg ttggattaag gctttttcca
     7801 atagctaaga atgttttctt tacgttgtat agtgctaaaa ctcggacgat gagatgatgc
     7861 taggtcagaa ttcttgttcg aaaaggtttc tgaccttttc tttatatttt tgtgactgac
     7921 ttatttgatg agacaaactc gctcctcacc tgacaagtgg attgctgtgt gaggaggaga
     7981 tgcggtgaaa aaagatcgat tggtggattt tgggtcctta tttgactttg tccatgatcg
     8041 gtcttttaga agtatacagt gccagttctt atcgtttatt gcaagccgat gaaaatacaa
     8101 aaagtctatt attgcgtcaa ctaattttca tatttttgag ttggagcgtg atcttcttag
     8161 ctcgttcagt caaactacac tatttacttc accctaaaat agcaggatac ggtttagcct
     8221 tatcgatttt ctttttagta ttagtaagaa tagggatatt cggtgtcact gtcaacggcg
     8281 cacaacgttg gatctctctg tttggcattc aattccagcc ttctgaactg gcaaatcttt
     8341 ttttgatttt ttatttaagc tggttttttc gtgacggaaa tagtagccca aaagatctaa
     8401 aaaaaccatt cctgattaca gtaggtataa cttttctgat tttatttcag ccaaagattg
     8461 ctggagcatt gatgatcctt tcgattgcgt gggtcatatt ttgggcagcg gcggttccat
     8521 ttaaaaaagg gatctatcta atcgttactt tttctgcatt gctgattgga gcagcaggcg
     8581 gggtattata tttaggaaat aaaggttggc ttccacagat gtttaatcat gcttatgaaa
     8641 ggatcgcgac tttaagagat tcttttatcg atagtcatgg tgcgggctat caaatgaccc
     8701 attcgtttta tgcactatat aatggtggca tatttgggcg gggattagga aatagtatca
     8761 caaaaaaagg gtatcttcca gagacagaaa cagattttat tttttcgatt attacagaag
     8821 agcttgggct aatcggtgca ttgtgtgtgc ttttcttatt gttctcatta tgcatgagaa
     8881 tcttttgttt aagcagtcgc tgtaaaaatc agcaagctgg attgtttctt ttaggattcg
     8941 gaactttgct attcgttcag acgataatga acgtgggaag tatcgcgggg ctgatgccaa
     9001 tgactggtgt gccattgcca tttgttagct acggaggaac aagttatctg atcctttctt
     9061 taggaatcgg aatcacgttg aatatttctt caaagataca ggccgaagag ttggcgctct
     9121 atcgacctga aaaacaataa agagaaactg agaaactctc agtttgaatt atcataaagt
     9181 acaatctttt atttttcaag cgagaggttc ttttagaaag aggaattcgc aatgaaagta
     9241 tctcaaaaaa tcatattatc tattttgtta ctgcttacat tagtagttgg ctatttttcg
     9301 attgagttta tccatggatt ttcgtctgca aaacagagtt caactgtgaa aaaggtagag
     9361 ccgaaaagta tccctaccac actaaatgtg gctttgattg gttcagatgc tcgttcgaaa
     9421 gacgaaaacg gtcgctcgga ttcacttctg gttgcacaat acaaccagaa aacacaacaa
     9481 gcaaaactga tctctatcat gagagattca tatgtcgata ttccaggtta cggaatgaat
     9541 aagataaatg cagcttactc ttatggggga gttgatttat taaatcaaac attaaaggaa
     9601 aatttcaaat ttgaagctcc ctattatgca agtatcacat ttcaagattt tatcgattgc
     9661 gttaatgaac tgtttcctgg tggagtcaag atcgatgcag aaaaatctct agatttagat
     9721 ggcgtatata taaacaaagg agagcaagtg atggatggta atactttact ccagtatgct
     9781 cgatttcggg aagacaaaga aggagacttc gggaggatca gaaggcagca gcaagtgatc
     9841 aaagctatct ctcagcagct gaaagacgta acttcaatat tcaagctacc caaagcggtt
     9901 gggaaattac ttggtagtat ccaaacgaac cttccagaaa gtgtgcttct ggattgtggt
     9961 atggatttcc tcaaagacat atgttagaat aaacaggtat aaatagtgaa ataaaggaat
    10021 gacaagcaag agaaggagga aaaaatgaaa agaagtgaca agcacggcaa aaatcgaaca
    10081 ggcgcttata ttgccggcgc agtgatctta atagcagctg cgggtggcgg ttatttttac
    10141 taccagcact atcaagaaac ccaagcagta gaagctggag aaaagacagt tgagcaattt
    10201 gtccaagctt tgaacaaggg agattataac aaagctgcag aaatgacatc aaaaaaggcg
    10261 gcaaataaaa gtgcattatc tgaaaaagag atcttagata aataccagaa tatatacggt
    10321 gctgctgatg tcaaaggact tcagatatcg aatctaaaag tagataaaaa agacgattct
    10381 acttacagtt tttcatataa agcaaagatg aatacctcat taggtgaatt gaaagatctt
    10441 tcttataaag gaacattaga cagaaatgat ggtcaaacca cgatcaactg gcaacccaac
    10501 ttggtttttc cagaaatgga aggaaatgac aaagtaagcc tgaccacaca agaagcagca
    10561 agagggaata ttatagatcg aaatggtgaa ccattagcaa caacaggcaa actaaaacaa
    10621 ttaggagtcg ttccaagtaa acttggagat ggaggcgaaa aaacagccaa tatcaaagcg
    10681 attgcttcct ccttcgactt aacagaagat gctatcaatc aggcgatttc acaaagctgg
    10741 gtacaacccg attactttgt cccattgaaa atcattgatg gagcaacgcc agaacttcca
    10801 gctggagcta ccattcaaga agtagacggc agatattatc ctttgggtga agcagctgct
    10861 cagctgattg gttacgtggg agatatcaca gcagaagata ttgataagaa tccagaatta
    10921 agcagtaatg gaaaaatcgg tcgctcaggt ttggagatgg cttttgataa ggatcttcgt
    10981 gggacaacag gtgggaaatt aagcattaca gatgcagacg gtgtagagaa aaaagttctg
    11041 atcgaacatg aagttcaaaa tggcaaagat atcaaattga caatcgatgc gaaggcacaa
    11101 aaaacagctt ttgacagtct aggaggaaaa gctggatcaa ctgttgcgac aacgccaaaa
    11161 accggtgatc ttcttgcgct tgctagctct ccaagctatg atccaaacaa aatgacaaac
    11221 gggatctcac aagaagatta caaagcttat gaagaaaatc ctgaacatcc attcatcagc
    11281 cgatttgcga caggttatgc tcctggatct acgtttaaaa tgattacagc agcaatcggt
    11341 ctcgacaacg gcactatcga tccaaatgaa gtgttgacga tcaacgggct taaatggcaa
    11401 aaagacagtt cttggggatc ttatcaagta acgcgtgtca gtagtgatgt atcacaagta
    11461 gacttaaaaa ctgctttgat ctattccgat aatatatatg cggcacaaga aacgttgaaa
    11521 atgggtgaga aaaaatttcg tacaggctta gataaattca tttttggtga agaccttgat
    11581 ttgccaatta gtatgaatcc agcacaaatt tctaatgaag atagctttaa ctcagatatc
    11641 ttgctagctg atactggata tggacagggc gaacttctaa ttactcctat ccagcaagca
    11701 gcaatgtatt ctgtttttac caacaatggc acacttgtct atcctaaatt gattgcagat
    11761 aaagagacaa aagataagaa gaatgtcatc agcgaaacag cagtacaaac gatcgtgcca
    11821 gatctgagag aagttgtgca agatgtaaat ggtacagcac attctctttc tgctttaggg
    11881 attccgttgg cagcgaaaac tggtacagcg gaaatcaaag aaaaacagga tgtaaagggg
    11941 caagagaaca gtttcttgtt tgctttcaat cttgataacc aaggttatat gatggtcagc
    12001 atgttggaaa ataaagaaga tgatgattca gcaaccaaac gagcatcgga actattgcaa
    12061 tacctcaacc aaaattatca ataaaaaatt gctttttaag tacagtaaaa ggactgtggc
    12121 gttatcgtca cagtcctttt ttcaaataaa cggttttcac gatgtctctt tcacaacttc
    12181 tttttgattt actcacactt cataaacttt ttttgtaaaa tatttgagaa caagtggaga
    12241 aataagtgta cttaataaaa tcacgataac taaaggtgaa tagtactgtg gttcgatcaa
    12301 ttgactttgc tgtccaattt gtaaaatgat caaagccatt tctccacgcg aaatcatacc
    12361 agcaccgacc atcaatgaac tatgttgaga aaaaccggca atctgagcac caaaataacc
    12421 tccaagcaat ttggtcaaaa tcgctacaag cgtcaatata gaaataaaga gtagttgttc
    12481 actaaagtca gaaaaatcaa cttctaatcc tacactgaca aaaaatactg gtataaatac
    12541 tgcatatcct aaagcctcta cattgtggta tacttcttct ttaacctttg tctgactgac
    12601 agctatccca gcaaaaaaag caccaatgac agagctaagc ccaacaagat ccgctacgta
    12661 agacattcct aaacaaataa ctagcgatac gatgataata gaagaatttg cgtacacttt
    12721 ttctgcaaat gaaagtagga aaggcgcaat ccatttgact aataagaaaa taaaaacaaa
    12781 ataaattagc tgttcaatca aaacaagcgg taaagaagca ttgctagaag cttcccccgt
    12841 tagaaaagat aggctgaaac ttagaactaa aacgactaaa atgtcatcta ccacagaagc
    12901 acccaaaatt gttgatcctt cttttgtatt cactacgttt agttctttta atacttctac
    12961 tgaaatactg acagaagttg ccgcaagaat aatcccaaag aaaatcgctt catttcccga
    13021 aacttggaat gctttgcctg tcaaccagcc aaaaacaacc gggaagatga tcccaagcaa
    13081 agcaacgaac ataccaggtc ggaaatattt tttcaaaaga gataaatcac tttccagacc
    13141 agctaaaaac attaataaga tcacaccaat ctccgaaaag tcatggacta gaatatcagg
    13201 tttgacccaa ttcaatccag cttggcctag caaaacacca acaagtaatt gtccaatcac
    13261 tgctgggata cctaatctcc gcgagatatg tgagccaatc gttgttgaaa tcaatatcag
    13321 gcataaaata ccaataaatt ccattctcat cattcctttg tataaaatat agcccgaact
    13381 tagcataaca tacattattg aaaaaatagg aaaatatact cacaaaaaaa ccaacaatcc
    13441 aaaagatttt tttggattgt tggtttttat acggtctatt ttaataacta aaaatgatta
    13501 acgtatagtc atttttctta ttctgatgaa attgataatc tcctggatgc ccatgaaaat
    13561 caaaataaag ccgaatattt ggaatagaag catcaaactt ttgaatggat tgaacaataa
    13621 gacgaatccg ccaatcaaca acagaatact actataaaca ctccaacttt tagcttttgt
    13681 attcatgctg aagaacaact ggaacaagct gttgatgata acagctaatc caagaagaat
    13741 cggcaggata gaaacgattg caggtgcaaa agcatagacg atcagagcta agatcaggaa
    13801 aaaaagacca ctgaacagac cgatactcca agaacctgtt ttccttttaa aacggtaagc
    13861 ctcaaaaaga ttcaacaacc caagcaaaac aagataggcg gtgatcagat aaccgataaa
    13921 atgaaaaaca gcagaagggt ttagcacaat cgcaatccca gaaataatat aaacagcagc
    13981 tcttaataag gcgtattttt gaatattttg tttaatcgtc tcaaacatat aagaaaacct
    14041 cctttgactt attttaacgt gaactagtca ttttaccaaa ttaaatgtta caaaatgagc
    14101 gaaggagaag aatatctctg gaaaaatcaa cttctgagga tcttttccat ttttttgcct
    14161 tttgctagct catcgatcat tttatctaaa taacgaattt ctttcatcaa gttatcctcg
    14221 atgtcttcta ctcgtacacc acaaacaaca cctgtaatca aggaacgtga aggattgggg
    14281 acaggggctt ccgcaaaaaa ttgttcgaaa gtcacttgtt tttgtagttg atattctagt
    14341 tctgtttggg aataacccgt cagccaacaa atgatttcat ctacttcctc ttttatacga
    14401 tcttttctct ccgcttttgc tacatacata ggataaacgc ttgcaaaact tgtcgtaaaa
    14461 atacgatttt gcgccataat cagtcacctt tctttttttc aaattattta ctacttatag
    14521 tatataagaa aaagagaaga aaaagcgatt attcaaaaaa acaaaaagga ttgtgacaaa
    14581 attcttgtca ccatcctttt ttccgctctc tgacttttta caatcttcat agctcaagtg
    14641 cgcatcagat aatcgaatgc tcctaaagct gcagtagctc ctgaacccat tgaaacaatg
    14701 atttgtttgt atggactatc tgtacaatca ccagctgcga aaacgccggg gatattcgtt
    14761 gcgccatttt tctcggtcac tatttcattt cttggattca tttcgatcgt tccatctagc
    14821 caatccgtat tagggagtaa gccgactaga atgaatactc ctgaaacagc tagtgtatgc
    14881 atctccatcg tacggcgatc gatataggag agagattcta cctgattcgt accgctgatt
    14941 tctttcgtcg ctgcatgttt gataacagtg acattcgcaa gagagactag tttatcctgt
    15001 aagatttgat ctgcttttaa ttctggtaag aattctagaa catatacatg ttttgctaac
    15061 ccagccaaat cgattgctgc ttcaacacca gaattaccac caccgataac agcaatctct
    15121 tttcctttaa ataaagggcc gtcacagtgt gggcaataag caattccttt atttttaaac
    15181 tctttttcgc ctggtacatt gatagaacgc cagtgcgcac ctgtcgcgat gatggcggtt
    15241 tttgctttaa gtgatatacc gttagctaag ccaatattaa taaaatgttg ctctttattt
    15301 aaggaaacgg cctgttgatt catcataatg tcgatagggt aactacgcac atgactttct
    15361 acttgctgca tcaattttgg accttctgtg taagaggtac caatcatatt ttcaatccct
    15421 agtgtttcaa cgacttgtcc gccgaaagaa tcagcgacaa gtcctgtacg gattccttta
    15481 cgtgctgcat agatagctgc actactagct gctggtccac cgccaatcac taatacatca
    15541 taaggttctt tttcaaacaa ctcttcttca atcaaagggc cagtgatttt ttcaacaatt
    15601 tgttcgatcg tcatgcgtcc gctactaaat tcttctccat ttaaaaacac agttggcact
    15661 gccatgattt ttttatcatc gatttctttt tggaacatcc caccttcaat catcgtatga
    15721 gtaatatttg gatttaatac agctaatata ttcaatgcct gtacaacgtc ggggcaatta
    15781 tgacaagtca agctaacata actgtcaaaa tgcaatgttt gtgttatttt tttgatttta
    15841 agactcaaag attcactgat tttcggtgcc cgtccactaa tttgtaacat agccagtaaa
    15901 aaagaggaaa attcatgacc gagggggata ccagcaaaaa cgattccact ttctttgcca
    15961 actggattga tagaaaaact aggtgtgcgc atcgaatctc ttttttccca agagatttta
    16021 ggagacattt ctgctatttc cttcgtaaat tcagctagtt tttgactatt ttcactatta
    16081 tccaaactaa cagaaaaaac aataggagat tcaatcagtg ctaaatattg ttcgagattt
    16141 tgtttagttt ctttgtctaa catatccacc acctaaatct ttccaacaag atcaaaactt
    16201 ggtttcaatg tttcgccact ttctttccat tttgccggac aaacttcacc tgggtgggta
    16261 cgtacatatt gagcagcgcg aatcttatca atcagtgcac tagcgtcacg accgattcca
    16321 tctgcattga tttccatagc ttgaacgatt ccgtctggat caataataaa tgttcctcgc
    16381 tgagctaatc cttgctcttc atccaaaaca tcaaaaatac gagaaatctg atgagacgga
    16441 tcaccgatca tcacgtattc gattttaccg atagcatctg atgtatcatg ccatgctttg
    16501 tgagtaaagt gggtatcggt agagcaagaa aagacttcaa cacctaaaga tttcaatgta
    16561 ctgtattgtt cttgtaagtc ttctaattca gtaggacaaa caaaagtaaa atcagctgga
    16621 tagaagcaaa gaatactcca gttccccata agatcttttt cactgacttc taaaaattct
    16681 ccttgatgat aagcatgtgc attaaattct tcgatttttt tcccaatcaa tgacatagta
    16741 aaacctccaa taataattat ttatttataa ttattgtaat ttagttggag ttgcaaagtc
    16801 aatggatatt ttgttattta ataaagatta ctcaaaaacg aaggttaatt ataaaaatag
    16861 aagaggtcgc aagaaaatgc tactgctgga aatactcggg ataacgttga gtaacagttt
    16921 cctgttcttt cagcatcatg tgtaagtgca atcccgtttg aaatcgagct tcttctggtt
    16981 ttttatcaac taaagccttg agtaaatcat aatgttgttc catgatcgtt tcccatggaa
    17041 gcccctgaat ggtcactcgt aaccagcgga aacgttctaa atgggtatta tggtcatcta
    17101 accagttcca aacttctttt cttcctgcaa tttcgaaaca agcttcatga aataaattat
    17161 ctgcacggaa aaaagcgcgt tcgtcattta ttttgactgc tttttcttgt tcttctaaaa
    17221 tcgtttctag cactattcgt gtttgtgtgt ccaatttgga acaacattca atcatgattt
    17281 gctcttccaa ctgttctcgg acaaagcgag cattttctgc agaaacaaga ttaattttgg
    17341 aaacatacgt accactttga ggtatcgtat acacgagttc ttgctgacgt agttgaatca
    17401 atgcttcgcg aatgggagtc cggccgatag caagatgttc ctccagtgcc ttttcagata
    17461 ttttccttcc aggttctaag tcagcataga taatttgttt acgaatcgct tgataagctt
    17521 gtgattgcaa gctgcttttc atctttattc ctccaaaatc atttctatga acgtagtata
    17581 acagaagagg tctgaaaaac aatctggtat gtcacattaa ctagtaaatt tgtataaata
    17641 gtaaaatttt ggttgacata gcgattttta ttgcataaaa ttcacttgaa tacaaaaact
    17701 aatatgttag tttaggaggg gaaaaatgat tgatttaaac aactggagga actttatccc
    17761 tgaattatct caaaaagaag tagaaatacc tcattttgac cgtgcatcat taagagaaaa
    17821 tggacaaaaa aatcctgtct ggatccattt cggtggcgga aatctttatc gaggatttca
    17881 tgcagaaatc gctcaacgtt tagcggatct aggcgaattg tccactggtg tcattgtttg
    17941 tgaaacattc gatgaagaaa taattgaaag ggcttaccaa gattttgatg atttgattct
    18001 tgaagtggtc atgccaagca gtggagagtt cgtcaaacgt atattagctg cgacagctga
    18061 cagtctgtat tgtcatccag attgttctga acactttgat aagatgattc gacactttga
    18121 aaatcctagt ttacaattag ttacttttgc tattactgaa aaaggttatc gattgaaaga
    18181 tacaaataat aaatatatag gaccgattgc agtcgatata aaaaatggtc caaagaagcc
    18241 atcacataca atgagtattc ttgctgtgct actttataaa cgttttttat ctggagcttg
    18301 gccgattgca cttgtctcta cagataattt ttcacaaaac ggtagtcaat tacgtacttc
    18361 tttgctaacg atcgcaaaag aatggcaaaa ggaaggttat gtacaaaata catttatcca
    18421 atacttatcg aatgaagaaa ttgttgcgtt tccatggacg atgattgatc gtatcacccc
    18481 gaatccttcc ttgtcagtta gcaaaatgtt ggcaaaagag ggcttttcaa atatgtcgat
    18541 tttccaaacc gcaaaaggaa ataatattgc tccatttgtc aatacagagg acatccatta
    18601 tttaatcatg gaagatcatt ttcccaatgg acgtccgaaa ttcgaaaaag ctggggtatt
    18661 cttgactgat cgtgcaacgg tagataaagc agatacgatg aaggtgacga cttgccttaa
    18721 tcctttgcat acgtctttag ctattatggg ttgtttactg gggtatagga gcatagctga
    18781 ggagatgaaa gatccagatt tatcgctgct agtttctgaa atcgggtaca atgaaggcct
    18841 cccagttgtg gagtctccag gtatcattga tccaaagatc tttctggaag aagtaattac
    18901 tgtgcgcttt tctaatccaa atattcctaa tatgcctcag cgaatcgcca cggatacctc
    18961 tcaaaaggtg gcgattcgtt atggtgagac gattaaaaaa tatatggaaa tagaagttaa
    19021 agacccgcag acacttgtat tcataccatt gactctcgct gcttggcttc gataccttat
    19081 tggcattgat gatcaaggaa aaccattcat cccgagtcca gacccactat tgacagacct
    19141 tcagcataag ctttccgata ttcaactggg tacgcaagat acatcacata ttcatgagaa
    19201 aatggctcct attttgtcaa ataaagaaat ttttggtgta gatctttacc aagcagagct
    19261 tggcagaaaa atagaagaaa tgttcatcaa gatggtagca ggaccaaatg ccgtacgaaa
    19321 aacattacag gattacttac aagaacatgg aggaaattta tcatggaaat gacttttaga
    19381 tggtacggat cacaggaaga aaagattacc ttagatgaaa tcagacagat tcctgcggtc
    19441 aaagggattg taggcacatt gatggatata ccagtaggag aggtatggcc tagggagagg
    19501 atcaaagaac taaaagaaga aattgagtct cgtgggttaa cactaaaagt aattgaaagc
    19561 gtcaatgtgc atgatgccat taaaattgga ttaccttccc gtgagcagta tatcgaaaac
    19621 tataagcaga caatccgaaa cttggcagaa tatggaatag aagtcatctg ctataatttt
    19681 atgcctgtat ttgactgggt gaaatctgac cttgactacc gcttagaaga cggctcatcc
    19741 acgttagctt ttatatctga tgatattcca gatgatccaa gagaaatcgt cgcgcgcatc
    19801 gaacattcca gcaatgaatt tggattgccg ggatgggaac ctgagcgctt agctcctatc
    19861 aaatccttgc ttgaagccta tgcatcagta gacgaagaaa aacttcgaga aaattttgcc
    19921 tattttctcc aatcaatcat cccaacatgt gaagaggtag gggtcaaaat ggctgtacat
    19981 ccagatgatc cgccatactc gatttttgga ttagctcgaa tcgtaaagaa tcgagaagat
    20041 ttagattggt tgtgtcgcat agtagacagc ccttataacg gaatcactct ttgtacaggg
    20101 agtattgcag aagatccaga aaatgatgta tatgggattt tagcagaatt ttgccaaaga
    20161 gatcgaatcc catttgcaca tgttcgaaat attaaatttt tagctaatcg agatttctat
    20221 gaggcaccac ataaatccga atacggttca ttagacatgt accgcatact aaaaacaatg
    20281 tatgacaacg gatttaacgg atacatccgt cctgatcatg gaagaatgat ctggaatgag
    20341 acaggaagac caggatacgg cttatatgat cgagcattag gtgctgttta tctaaatgga
    20401 ttatgggaag caatcgaaaa aggaaacaaa agtaaagata attagtgaaa aaaactgtaa
    20461 ttttattatg taaataagaa ggatgttcaa attcttgata cataaatccg gaggttgtta
    20521 ataagcattc ggatttatgt atcttatttg gtctaggaag taacttgatt ttcttttttc
    20581 gattgatcca tgagtgcttc ttcttttaat tcaaagatat attctgagat cctcataatc
    20641 acttttttcc agtcttctgg tgtgatgatt ccttttaaaa tatagatttt tttgatatga
    20701 gaaggcaatt gtttcaaagg gcagtcgctg ataacgatgt tgcagttctc cataaaatca
    20761 ttttgtattt tgatcgattc atttgaaaaa atttgttcta tcttaacgat cagatcttta
    20821 ctgatataaa aatcacgcgt atagttcaca ccaatcacaa ttcgcggctg ttttttgtag
    20881 cgatcataca aatgtactag gtcttcaacc atccattgca cattttcctt ttctaaaata
    20941 actggtaaca agtgttgatt ttgttctctg aaatccatat aaaattgttc aatggcggtt
    21001 tggacttctt tcaatacgct atgttcttga taaagcatga aagtaggaag gggcgtattt
    21061 ggttgattga agttaagaaa tccattataa agtttatttc gtgcgaatgc caatgagtaa
    21121 agaatctttt ctttttcagg tataaacaaa tcaaatacag tacaaaggga ctccaccatt
    21181 tctcttgaat aaagaacatg aggaacgttt gcttttttta aaagtttgta ttgctccaag
    21241 cttgtttctt ccgattcgat tttcgtgata gaaagtcgag ctaaaatatt cactaagatg
    21301 cgttgttcgc gacaaattgg cagattaggt cgcaaaatat ctacagagag atcaataaaa
    21361 aagtcaatat attcatactc tgtgaattct ttttgtacgt ctttcacaga agttgcagga
    21421 aaattctctt tacatatttt taatagaaaa tataatttat ctatcatacc gctatttagt
    21481 cggtcaagta cttctttttt aaaaaaagta ttcatcataa aagccactac ttgcggatct
    21541 tcatcataaa attctgtagc agtacttgaa aagatgttcc aataaatatc taatgctgca
    21601 tattgaattt gtacctcttt tccagaaaaa gactttctgc cattattaga aaaggagata
    21661 gacaaaccgt actatgctaa aaatgcatta atctttttca ttttcgtata caaataagag
    21721 gcactatagt ttgtttgctg actgaaactg ataatcgaat ttgtctgaca gctgaacaaa
    21781 gaagtcaaga tctgataact gactgattcg ttgcagtatc ttccaaatag acgataatag
    21841 cagtaagccg gatcaattcc ttcaaaattc aactttaaaa aaggtttttg cttatcaata
    21901 tgcagttctg ttagattgag acgctcaaag tcttgttcta attctttgat gtatagtaaa
    21961 aaatttgatt cagacatatg gaaatgatct gctaaatatt gtgtagtaat aaagaaacga
    22021 tgttcagata ggaaaagaaa aatatctaat tttgtattgc tttttttctt caagataaac
    22081 gttttaatcg cttcttgagt ttgcatgaaa gaggctcctt tttacttaaa ttgttaaaac
    22141 ttgaaaatat tactgttttt ttcataaatt tagacaaaaa aacagtaaac atataggtag
    22201 aatctctact atcttatttc ttgcatacaa aaaaatcaag gagtgagaga gttatgagat
    22261 attcaaccat cttaatatca acatttgcag ccttaagctt atcgcttact ataaatcaga
    22321 cagtccacac agaggagaca gaaacagcca aatggacaga aaccaagtgg gccaacgtca
    22381 atcgaattac ctttcaggat gaattttcat ccttcaattc aggagtcgca aaattaagaa
    22441 aaggacaaac agcgaccatc aaagcaaaaa ttgactattc gggagactta gcacctatac
    22501 tacaatcagc tgttacattt gagaatgttg atcccacttt gtcgattggc tatgacgaga
    22561 acactttgac tatccaacac aagcaagcga tatttacctt caccgttaca ttaaatcagg
    22621 acttgttaaa accagcgctt tttactgtca aggtatcaga tggactaccg aacgatcatc
    22681 atttaacgcc gtatagtcag cggcagacaa ttgagcaaga ttcagccatc gactcaggag
    22741 gagatcttgt tgaagaacca acagataaac cagaaaatga aaataagcca gaagtaccgc
    22801 ctacagaaaa tccagacgga gaacagaaac cggaaataga acctggagaa gaacccgata
    22861 cagaaactca accagagcca gacaataaat caaaacctga aataacccct ggagaaaaac
    22921 cagatgtaac tccagaacca gatacggatt ctggaaacca aacagtaccg gaaacaaatc
    22981 cagacacaga taatgaaact gaaaatccag aaaaaccaga ggtagatcca gaagaaaaac
    23041 cagatgtgac tccagaacca gatacggacg caagagacca aggaatacca gaaaaaataa
    23101 acaaaaaaac aattcaagag gatggaaaaa aagagagtaa aaaatcaaat ctagcaattc
    23161 taaaaataaa tgaagagcag ctgaataaaa aatcacgaat atttgatagc gcccaatcag
    23221 ctgaaacctt aaaaagtagc aaggatacaa cctttgctgt cctgaaacga aaaataaaca
    23281 gctaccaaaa tccggagagt cacaaaacaa agttatactg tggagcggaa tcattctatt
    23341 aagtatagca acaatgcttt ctgcaaaaag atttaaacaa aacagatctc tctaacattt
    23401 gaataatgtc tgtgaacgca tttttcaaat aaaaagaaat atccagaaaa tgaccccaaa
    23461 ataccagatt gaaatctgat atttggggtc gttcatactt tatctttctt catatttatt
    23521 ttaagggata tctgtttctt ttggaagatg gttcgggatc tttttcactt tcaatacatc
    23581 taaaaagaag gtaaagatcg gaatgccgac aatcaagccc caaacgccaa agaaccgttc
    23641 gctaacaagt aagaccacaa atgtataaaa aatcggcagt tctgttttgc tggacatcaa
    23701 cttcggattc agcacataag actcaattag atggacaatc aaaatcgtaa tcaggatata
    23761 aacaacatct cggatgcctc cttgggaata agctatgaaa gatagaggaa tacaagaaat
    23821 gataacacct gctactggga tcagacttaa aatgaaaatc atgatcgcta aactcagcag
    23881 ctgatgaaag ccaaatacag ccaaggcgat tgtagtgagc aacgtattta aaagagcgac
    23941 aacaaattga gcttctaata ccaaaccaaa tgtattgaca aacttatcgg caaaatagta
    24001 aatatcttga aagaaccaag aaaattcact ttttaaaaac aatcttgaga atacaattgt
    24061 ttttttcttt tcaatcataa aaaagaaact taagatgaat gacatagcaa acgccactgc
    24121 catttttcct atatcctgta aatagccaag cgcaatcgaa gcgccatttt gaagctgttc
    24181 aaaaaaatcg tttcgctcaa tataagtatg gatatattgt aaaacaggat ctgcatcttt
    24241 tggctgatgc tcgtaaaaat taataacgga ctggatcatg tcaaatgttt gatgaataag
    24301 catcgggata tactttgtga atgccagata gataaggtaa acgatcagtg tataaatcat
    24361 gatagctaaa acacctgtag ggattcggac aaatcgctga atgatttgaa caagatgaat
    24421 catcaaataa gtaaagataa atgtgagcaa aatggttgta atcatacttc taactaagaa
    24481 aagaacaaaa acgacaaata ataaaacagt gagacggcgt attttttcat tcgccaaaaa
    24541 acgctgataa acggtcaaat cgacaacctc caaataacaa aaaataaaca cgttattcat
    24601 tatatgatgg aatatgaaaa taagaaagag caaaaagaaa aaccgctaaa tgacgttatc
    24661 ttatgagttg gttttcctca taaaatcgtt catctagcag tttcagccct ttttctggtc
    24721 ttgatgaaaa ttatctagca tttttcgggt cagatgttgc agtgtatcca attcttcctg
    24781 ttcaagtgga agataagact tgatcttttg tggaatacct tctgcttgtt tttgcaacgc
    24841 agcaccttga gcagtcagcg taacatttac gattctttca tcacccgttt cacgctgacg
    24901 attaatataa tttttttctg ctaacttttt tagtaaggga gtcagcgtac cagaatccag
    24961 acacaaatca tttcctagct ctttcactga agtctttttc ttttcccata aaactaacat
    25021 cacaagatac tgggtatagg taagattcag cggcttgagg aggggagtgt agtgtctaat
    25081 gatttcttta gaggcggcat ataaaggaaa acatacttga ttaactaaat atagatcttc
    25141 catttttcca cctccgctgt tttactatag tgtatcatag cggatttaca caaaaaagtc
    25201 tattcactaa ctgctttcag agtaacttct atatttccag ctgtagcttt tgaatacgga
    25261 cacactttat gcgctgcctc taataattct tgcgtttctt ccagagaaag accttcgata
    25321 gatccttcaa tctctacacc taagacaaag ctcgtttcac tttctgaata aagggaaact
    25381 tgtgcactga cagtagaagc cccagagata tttttttgct gtttgatcaa ttctaatgca
    25441 ctgttaaaac atgcactgaa accagctgca aacaattgtt cagggttggt tgcattttcg
    25501 acgcgtttac caggagctgc aatattcaat tcgaatgtac gatcgggatt atgcacttct
    25561 ccagagcgtc cgcctgtgtt gatcattttc gtagaataca tttttttcat aaaattacca
    25621 cctttaatta tattttatac aattgaattt tacacaatat aattgtggaa agcaaagaaa
    25681 tggattggca taagataaat aagagaaagc acatgaaaca gacgcgcttt ctcgaatagc
    25741 aaacatatac aaaaaatatc agagacaaaa aataatctca tcataaacat tacatatatt
    25801 tctcaaaaag ttgttttctt tcttcaaaaa ttacttcacg atggacctga tgaagcatcc
    25861 ataaataacc aaaaggatct ctgaacattg agttagtcac accaaagtcc atcatttctg
    25921 tcatttcttg aatctctaca cagccatttc gtaatgcttt attatgtgtg tcctcgatat
    25981 cagagacgat gatattgaac cagatcgtat ttggatgttc agcagtagga gcagtcaaac
    26041 caagagacgt gttttcatcc agcatatgga atctcgtacc atacaaggta aaaatgactt
    26101 cattattgcc tctagggtaa tctgttgcct caatcagttg tatttcatca aagattgttt
    26161 gatacagttc tagtgctttc aaactatcat ttaatacaaa atcgatttcc gttcctttat
    26221 gcataaagat ctcctctcct tttcagtcga acagttacta gattctttta ttataccagc
    26281 taaagaaaac gcattcaaaa aaatagcgga tttacttacc aactcattcg attggatgat
    26341 aagtaaatcc gcgtcccatt acttctgcta cgctgctgac aatgacaaag gcacttggat
    26401 cgatttcttc tatcaatggt ttcattcggg aaaattcatg atcagtcaca acgatcaata
    26461 aaacctcttt tgactttcga ttatacccgc cttttgcctc tagcagggta aggccacgtc
    26521 caatctcagc acttaagcga aggcggatgt cttccaaata atgttcactc atgaccataa
    26581 cagatttctt tcgattgata cctgtttcga tataagtcat gacaattgaa gtgattgcaa
    26641 tagataaaat agcataaaga aactcttcta ttccaaaaat aaacagatta agagaaacaa
    26701 cgaatgcgtc tgtaaaaaat aagccaatcg aagtattcaa gtggaaatat tttttaaaaa
    26761 tgaggggagg gatcgtcgta ccgccgctag aagagttgtt tttatataaa atcgcaactc
    26821 ctaaagcaaa aatcgcactt ccaaaaatga cagacaacaa ccgatctgaa gtaatcattg
    26881 tttctggaac tattgcaatg attaaaggaa aaaccaagct tccgaaaagt actttaaaaa
    26941 agggtttttt acctaaaaat agaagagcta gtaccaacat aacgatattc aacactaaaa
    27001 taactatagc tcggtcaaag cctaaagcag cttccagtaa tattcctaga ccgctgacac
    27061 ctccagcagc aatatgatga ggccctaaaa acatattgat agcgactcct aatatgaaga
    27121 gggcaaaaat aatcttaatg tatgtccata taaattgtct cgtttctttc atttattcac
    27181 ttccttaatt cattaataat actcttatct tattataact tacttttcac cttaagttaa
    27241 ctttaattaa taaaaaaatt aggctagtct aaattattat gtttcattct tctagaatat
    27301 acttctacgc caaaaactgt taaaaaactt ttactttaga aaattggaga aattgatcgc
    27361 ttaagataaa ttcaggacac taaatagtac aggaagtaga ctaaaacttt taaaagtttt
    27421 aagtctatct atttggcaag tttaaaaaat aaaaattcgg tatcaaaaaa ctgttaccga
    27481 taacattttt gaaagcgttg tcttttgctt ctctatcact tatagtgatg acgtcatatt
    27541 aaaacacaag gaggaaatca atggatacag ctgcaattta tcatcgaccg gaaagtgaat
    27601 atgcatttct atatacgaat acaagatttc gtattcggct tcgtactagg aaaaatgata
    27661 tcaaaaaagt atatgtgcta tgtggagatc catataccat aacaactgaa aaatggtatc
    27721 aaaaacaacg accaatgaaa aaatgtctaa gtaccaatgt tcatgattat tgggaaattg
    27781 aagtgacgag cgaaacaagt cgcttacagt atgcgttcca tgttgttggg gaagataaca
    27841 cggactgttt ttacggtgat caaggaattt ttccttatcg agaaaatgtg attactgaac
    27901 caaattttta ttttcgaata ccttattttc atcaaatcga tcgattcact attccagaat
    27961 gggtaaaaga aacagtatgg tatcaaattt ttcccgaaag atttgcaaac ggggacaaag
    28021 caaatgaccc cgaacacact ttaccttggg gaagtaaaga tccagaccga gaagactttt
    28081 tcgggggaga tttgcaaggt gtgatggatc atttggatta cttgacggac cttggcatca
    28141 atggcatcta tttttgtccc atatttaaag ccacatccaa tcataaatac gatacgattg
    28201 attattatga ggtggatccc gcttttggcg ataaaaaact tttaaaaaac ttgattgatg
    28261 aagcacataa aagagggata cgtatcatgt tcgatgctgt attcaatcat atgggtgtcc
    28321 attcaccaca gtggcaagac gttctcaaaa acggagaaaa atcgatctat aaagactggt
    28381 tccacatccg ttttttccca gtagattctt atcagatgac tgacttacca gaaactgctg
    28441 aaaatatccc atatgatact tttgctttta ctccattcat gccgaaacta aatacagcaa
    28501 atccagaagt gcaaaaatat ttgctggata tcgcaactta ttggataaaa gaattcgata
    28561 ttgatggatg gcgtcttgat gttgctaatg aagtcgatca tcatttttgg aaaaaattca
    28621 gagaagcagt tacagaaatc aaaccagaca tctatatcct tggagagatt tggcattcct
    28681 ctcaagcttg gctgcaaggg gatgaattcc atgcagtgat gaattatgca tttacagatt
    28741 cgattaaaga ttattttgca aaaaagaaaa tcacagcttc acaaatggtc agtggaatga
    28801 atcatcagca aatgctttac agagatcagg tgaacgaagg aacattcaac ttattagatt
    28861 ctcatgatac tgccaggatc ttgacccttt gccaaggtaa caaagaattg atgaagtctg
    28921 tgatggcctt tatgtttctt caaaaagggt ctccttgtat ctattacggg acagaaatag
    28981 ggatgactgg tgaagatgac ccggattgcc gcaaatgtat gatatgggag aaggaggaac
    29041 aagatctaga gctattcggt tttataaaag aacttgtttc tctaaggaaa cagttgtcta
    29101 agattatttc tgaaggttct actcagtggc taatagtaaa tgatcgtgaa gataagctct
    29161 atttcacacg gaaactagag ggacagatca tctatgttta ctttaatcag tcaaaagaac
    29221 cttgggtagt agaacaggaa aatgaggtga ttcttagtca aaattgtcag ttgttagaag
    29281 acgggaaagc agagatacga caatacggat ttttgatcat gtgttgaaaa ctgttaccgg
    29341 taacaacaag aaagcgtttg caaatgaaga tttgtgccca ttataataag ggtgtaacag
    29401 cacgttgaat acaaaggagg aaatgaagat gaaaaaaaga agtgtgaaac agttgggttt
    29461 agggttaatc tctttaggaa tcttaggcgg attagcggct tgtggcaatg gtaactcttc
    29521 agcagaaggg gaagccgatg aaggaaaaac gttaacagtt tccgttgatt ctggatataa
    29581 agattatata aacgaaataa aaaacacttt cgaaaaagaa aacgatgtga aaatcaagct
    29641 agtagaaaag gacatgttcg atcagttgga atcattagcg ttagatgggc ctgctggaaa
    29701 gggacctgac gttatgatgg cagcatatga ccggatcggt gcgttaggac agcaaggaca
    29761 tctggcggaa gtaaaactgg gaaatgaagc agcttacgat gaaacagaca aagcccaagt
    29821 gacttatgat ggaaaaatct acggagaacc tgcagtaatc gagacccttg ttttgtacta
    29881 taacaaagat ttagtcgata cagcaccatc aacgtttaaa gatttggaga atctatccaa
    29941 agacagtcgt tttgcttttg agtcagaagc aggaaaaaat acaggatttt tagctaaatg
    30001 gactgacttt tattattcct atggtttaat tgcaggttac ggtggctatg tatttggtga
    30061 tgatggcaca aatccttcag atatcggttt gaataatgca ggtgctgtag aaggaatctc
    30121 ttatgcaaca gattggttca aaaatgtttg gccaaaggga atgcaagaca taaaaagtgc
    30181 aggagacttc gccagccagc aattcatgtc caataaaact gcagcaatca ttgacggtcc
    30241 atggcaagcg caaacataca aagaaaacaa tatcaattat ggtgtagcca aaattcctac
    30301 tctaaataat ggacagcctt atcaaccgtt tggcggagga aaaggatggg tagtcagcaa
    30361 ttatgctaaa aacaaagacc tctctcaaaa atggcttgat tatgtaacga atcaggaaaa
    30421 tcaagaaaaa ttctttgaaa tggtaaatga aatccctgca aaccaacaag ctagggaaac
    30481 agcaaaggct aaaaacgatg aattaacaac agctgtgatt gaacaatatg aaacagctca
    30541 agcgatgcca aacatcccag aaatgggcga agtttggaca ggtgcagaaa acttgatgtt
    30601 cgatgcagca tcaggttcaa aaacaccaaa agaatccgca gatgaagcag taaaaacaat
    30661 cagtgaagcc atagaacaaa aatactgatt aaaatgataa ccgtccattt ttataaaaaa
    30721 tggaacaggt gcttcagata aaagtggcaa gagcgagatg gaaaattatc ttgctcttgt
    30781 tgccattatc ttaaaagcag tttgcggttt agcaagttta gagggggcat tcagatgcag
    30841 caagataaaa caagcaatat caacgaaaaa aaaatcacgc tttgttcact tattccaggg
    30901 atggggcagt ttgtaaatgg ccaagctttt aaaggtatcg tttttttcgc catattcgtc
    30961 ctattcattg gtcagatgct tctgggcgga tttcatgcat tggtaggatt ggttactttg
    31021 ggaagtatac caatggaaga tcattcatta tttattttga ttgaaggcac tttgcaattc
    31081 atcattacaa tcattttctt gattttttac ggtttgaatc ttttagacgc ttatcgagta
    31141 gcgaagatgc gtcaagaggg caaaaaaatc aatcggacga tgaaggaagt catacataat
    31201 ataggtgatg aaggttttcc ttatctattg acacttcccg cttatcttct catgattttt
    31261 acgatcattt tcccagtcct agttacattg ttcactgcat ttactaatta tgacttcaat
    31321 catattccac cagccagttt aattgattgg gtaggggcta aaaacttttt tagtatcttc
    31381 tttttaagct catatcgtaa tacttttttt gcagtctttt cgtggaccgt gatttggact
    31441 ttatgtgcaa caactttgca aatcaccctt ggtattctca cagcggttgt tgctcaccag
    31501 aaatttatta aattcaaacg tattttcggt atcattttct tattaccatg ggcggtccca
    31561 gcttttatta ctatcatgag tttttcgaat atattcaacg atagcgtagg tgccatcaat
    31621 actcaagtga ttcctttcat aaaccagctt ccttttgtag atatcagtgc aatctcttgg
    31681 aaaacggacc cgaactggac gaaagtagca attatcttag tgcagggctg gttaggattt
    31741 ccctatatct atgtgatggt tacaggaatc ttacaatcga tttcagaaga cttatatgaa
    31801 gcagcaaaaa tcgacggagc aaatgcatgg cagcgctttt caaacatcac gcttcctgct
    31861 gtcttcctag tggcagcgcc aacatttatt acacagtata cggggaattt caataatttc
    31921 tccatgatct atctgtttaa caatggcggt cccggaagcg taggcggagg agctggttct
    31981 actgatattc ttatttcctg gatctataaa cttacgactg gaacttctcc gcagtattct
    32041 atggcttcag caatcacgtt gattatctcc gtcatcgtta tctgtgtgtc attgctggta
    32101 tttaaaaaga caaatgcgtt caatatgggg gattaacaat gaaaaaattt cattcgagtg
    32161 ctcgattcca aaaacgactt tctcactttt ttacttactt ttttctttta atactgtcag
    32221 tcattatcat ctatccgctt ttgatcacag caagtactgc cttcaagtca ggaaatattg
    32281 cagcttttag tttagatctt tcaagtgact ggactttagg aaactttact cggctattca
    32341 gtgaaacact ttacgggact tggtataaaa atacattgat catttctgtc ctaacaatga
    32401 tcgtacaagt gactgtagta actttggcgg gctatactta tagtcgctat cgttttatcg
    32461 gccgcaaatc aagtttgatg ttctttttag tgattcagat ggtaccgact atggcagcat
    32521 tgactgcctt ttatgtcatg gctttcttat tagaagcgct cgataagtac tggttcttga
    32581 caatgatcta tataggcggt ggaattccaa tgaatacttg gctgatgaaa ggatactttg
    32641 acactgtacc aatagattta gatgaatctg ctaaacttga tggggcaggg catttcagga
    32701 tttttttcca gattgtatta ccgcttgtca aaccgatgct cgccgttcaa gcattatggg
    32761 cttttatggg accttttggg gatttcatgt tagctaagtt cctgcttcga acacctgaaa
    32821 atcagactgt tgctgtcggc ttacaaacat ttatttctga tgtgacaaac caaagagtct
    32881 ctctttttgc tgctggggca attttgattg cactaccgat ttgtctatta ttcttctttt
    32941 tacaaaagaa ctttgttacc ggcctgacat ctggcggaac aaaaggatag gagcagagta
    33001 tcatgcaaac atttccgtta aactattttt ccgcattacg tacgccaact caagtgtttg
    33061 cgggacgcaa actattatca tggcctaaat ttttcttgat atttgtattt ttagtttcct
    33121 tgatggtcat gcctgtgact cttttttatg ccaatcagat ccaagcgatt ccattagaac
    33181 aatttctatc cgttcattcg ctgatcgatg aacaaggaac ccaaaaattt tctgaacttg
    33241 aattatctga aactgggtta caagcatcgc aacaaacgat agctgtgacc cctgaaattt
    33301 tggtaggtgt gtctttatct gagaaacaac aatccgatca tggaactttt attgattttg
    33361 agaaggaaca atgggtgatc caacaaaagg ataaatctgg tatacgccgc tatacgatga
    33421 attatagccc atctttccaa ccagattctg tacgtacgcc cgaagatttc caacgatttt
    33481 tagaaagaga attttatgcc agtaatcgtc caacaatcat tttatcttat agtttaagtc
    33541 ttggtcttgt cctatttgtc atgacgagtc tcattttatt cggggcttcc tttttcttgt
    33601 ggatgacaag aaaaagccaa ctttcatcca ttcatacatt caaagagagt gcaaatttga
    33661 tgctgaatgt tatgggaata ggttccatgg cagcagcagt tgtagggttt atccactttg
    33721 actttatctt gatgctaagt gtccaaacaa cgataactgt cttgctgctt ttatgggttt
    33781 ttgtcaaaac aagattcaaa gataagcgtg tcgaatgaca agtttaagcg atttatgcga
    33841 caatgaatgt gaaaaaaatg aaaaataaag tagtttttga aaaatttctg aaaaaattaa
    33901 acttcttagt tgattctttt cttttttagt attaacgtaa tagggtagtt tttttaagga
    33961 ggaaaatcat gttagagaaa actttataca atcaattatt ttcacgttct ttctcgctcc
    34021 ctgtcgaagt aaattattgg gacggtacaa cgaaacaata cggagatacg gacactcctc
    34081 cccaaatcaa aatcaatatc catgaagaaa tcccaatgaa agagattaca agtaacgcat
    34141 ctttggcact aggagaagcc tatatggatc atcgaatcga gatcgaggga agtatccaag
    34201 cattgatcaa cgatgcttat cagcaagcaa acagcttttt acgaggaaaa gattatctaa
    34261 aatggctgcc aaagaaagaa aaacatacga aacaaaaaaa caaagaagat atccatgcgc
    34321 attatgactt aggtaacgac ttttataaac tttggctaga tccaactttg acttattctt
    34381 gtgcttattt caatacacct gaagatacgt tggaacaagc acaaatcaat aaagtccatc
    34441 atatcttaga caaactcttt atcaaagaag gcgaaacgtt gcttgatatc ggttgtggct
    34501 ggggaacatt gatgttcact gctaccaaag agtataatgt caaggcaact gggatcacac
    34561 taagtgaaga acaatacgat ttgattacca aaagaataaa agaagaacat ttagaagata
    34621 aatgccgtgt attattaatg gattaccgcg aactaaaagg cgaaacgttt gatcatatca
    34681 caagtgtagg tatgttcgaa catgtaggtt ctgaaaatct tgaaggttat ttcaaagtgg
    34741 taaaagattt attgaaacca aaaggaacag ctttgatcca tggaatcagc cgacaacaag
    34801 gcggtgcgac aaatgcttgg atcaataaat atattttccc tggcggttat gtccctggtg
    34861 ttactgaatt agttgataat attacaaaaa acgatttgca actgattgat ttggaaagct
    34921 tacgtcgtga ctaccaattg acattagaac attggacaaa gaattttcat caagtccaag
    34981 atcaagtcac gaaagaaatg ggtgattcct tctatcgaat gtgggatcta tatttacaag
    35041 cttgtgcagc ttcatttgaa tcaagtaata tcgatgtgat tcaatatttg cttgttcaac
    35101 ctggaaacaa tgacatccca atgcatcgtg cataattgag gcaaaagtac tgtttaaaga
    35161 ctatttaaaa agaagctaag ttttatgatg ctccagaagt gaactttttt gtctaacttc
    35221 taggattgtc tctaaagctt agtttctttt tctttatatt ttcataataa aagtttggtt
    35281 ctttaatttt taaacatgac agaaaatttt ttcttcgtta tacttgtaat agaatactat
    35341 tttataacaa aggggatcga atcaatgaaa aaaactgtta tttatactag tttatttgca
    35401 gctttgtttt tagctgcttg tcaatcaaat accaatcaag gcacatctgg gaatacgtct
    35461 tccagtagcg aacagcgctc ttcacaggta tcggactcct caacaaaagc aagcacatct
    35521 tcgtctagcc agacaaaaag ttctagtgaa gcaagtactc agtcagatat caaagtgtct
    35581 gcagctcgtg cgatcgaatt gttccaagat aaatacccag atactgcaat tactagtttg
    35641 gaattagata gtgattgggg atcttacttc tacaagatag aaggtgtcga tgatcaaaaa
    35701 gaatacgaag caagaattga tgctcaaaat gaaaaaatgg agacagagaa tccagaaact
    35761 ctagatcgag atgaacaaaa tggtcaaaag aaaaaagaag atggtctgga tgttgataaa
    35821 ttgatcacga ttgaggaagc agcaaaaatc gccgtcgaca aagtaggaag cggtacggca
    35881 acagattggg atttggataa agatttaggt actacttatt gggaagtcaa agtaaaagac
    35941 ggcaatcaaa gtacatcagt caagatcaat agccaaacag gcgaagtact gtcaactgaa
    36001 caagatgatt aagaatttct tcggaaaaca agagttgatt tttcttttag tcatgataca
    36061 ctagacaaaa taacttgttt gaaggagcga tttacttgag tttagaaacg acctttgcca
    36121 atcatatctt tgccaatcct ttgatgaatg catctggtgt ccactgcatg actacccagg
    36181 aattagatga actggctcat tcagaagcag gagcatttat cactaagagc tgtacgatca
    36241 atgaacgaaa aggaaatccc gaaccacgct attttgatgt tcctttaggg agtatcaatt
    36301 ctatgggact tccaaactta ggtttttctt attatctaga gtatgctctt gcgtatgaaa
    36361 aagtgcagga aaaccaaaat caaccgttat ttttttccat tgccgggatg agtgtccagg
    36421 aaaacttgga aatgcttgag aaaatagaaa aaagtgggtt taatgggatc actgaattaa
    36481 atttatcttg tcccaatgtg cctggaaaac cacaactagc ttacgatttt gaggccactt
    36541 atgaaacact gaaagaagta ttcagcatct tttctaagcc gctaggaatc aaattgcctc
    36601 cttattttga ttttgctcat tttgatcaga tggctgatat cttgaatcag tttccattga
    36661 cctatgtcaa tgctatcaac agtgtgggca atggtttgta tatcgataca gaacaagaag
    36721 cagtagtcat caaaccaaaa gaagggttcg gcggcattgg cggagagtat atcaagccga
    36781 ctgctttggc gaatgttcgc gctttttata cacgtttgaa accagaaatc caaatcattg
    36841 gtacaggtgg gattcggaca ggacaagatg catttgaaca tctgctatgt ggcgcaagca
    36901 tgttacagat tggtaccgag cttcataaag aagggccgga aattttttct agaatcataa
    36961 aagaattaac gcagattatg tcagaaaaag gatatacgtc aattgacgaa tttaaaggca
    37021 aattacgcac catttcatag caaagagacg aaggtcatga ttgatcttcg tcttttttta
    37081 taaaaaacac tcgtctgttc attcctgtgc aagcgtactc attgtatgtt agacgaactt
    37141 gtgggaaaat aacagaggca aaaaggagga taatatgaat gatgcaacag aattagcaaa
    37201 agagcttaaa gaaaaagaat ttagttttca agaactagtt acggatatac agaaaaaaat
    37261 aaagaagcaa aatcatgaat tgaatgcgtt tgtcgcgctt gaaccattcg agagtaattc
    37321 ccacgagcta ttgattcccc agtcagaaaa agggccattg gctggtatcc catttccttt
    37381 aaaaatgctc ggtcaagaaa aaaagggatg gctagctact tcaggatctc gtttatttga
    37441 aacacaccga gcttctcata catctaatta tgtgcggcaa gcagaagcga taggtctagt
    37501 tccttttgga caaaccaatg cgccagagtt tggtttcaaa aatattacag acccagtcat
    37561 ctatggccca gcaagaaacc cttggaacct tgaatgtaca ccgggcggat caagtggagg
    37621 agctgctgct gcagtttcat caggaatcgt tcctttagct ggtgctagtg atggcggtgg
    37681 ttctattaga atacccgctt cgttttgcgg attgattggg ctgaaacctt cgcgagggac
    37741 gatgccagtt ggtccatatg cttggagagg atggcaagga gctgctattg atttcggctt
    37801 gacagtttct atgagagaca cggaggcttt attttatggg atgagaagta tccattccgg
    37861 tgcgccatat caagtatcgc cagttgagtg gcaaacacat ccaagaaaaa aacggttgaa
    37921 gatagctttt tgtgttgatt caccgatcca ctcacagatt agtgaagagg cagtacttgc
    37981 tgtaaaaaaa gctgtagatt tccttggaaa agaagggcat gatttgacag agattcctta
    38041 cccactagat ggtcgtaaac tgatcacgtc ttattatcag atgaatggcg cagaaacagc
    38101 agcaatgatc cgctcgattg aaacaggcat ccagcgagct gtcagaaaag aagaacttga
    38161 acccatttct tggactttgt tccaatatgg tcagaagctc tctgccgcta cttacatcga
    38221 ttctctgcat gtatgggatg aagcagcaat tgtcatggaa aacctacatc aagaatacga
    38281 tctattcctt tcaccaacga ctgcatttac cgcccctaaa atcagcgaag atttgcaaag
    38341 tgatgcgata agagcacaga tggaacacat cagtgattgt tctgaagtag aaggtttaga
    38401 cgttgtttct tccatgtttg aggagagctt gaagatcaca ccttatacac agttggctaa
    38461 tctgactgga caaccagcaa tcagcttgcc tactcatttg acaaaagaaa acatgcctct
    38521 aggaatccaa tttatggctg ccagaggaag agaagatttg ctatttcaaa tcggctatct
    38581 atttgaagca aatcatcagt tccatttacc aaatccatgg aaatagcaga aacaaggaga
    38641 agaagaatga agaaaaaaag attgtttgct ctaataacta gtgccttttt tattttaagc
    38701 gcttgcggta cagctgccgc taatcaggaa gataacagct ggagtaatgt agaaaaaaag
    38761 aaagaattag tagtagcgac ttctggcaca ctgtttcccg catcttatta taatgatcaa
    38821 aatgaattag ttggttatga tgtagatttg gcaaaagagg tggctaaacg gttaaatgtc
    38881 aaaatctcct ttaaagaata caacgtggat ggacaaatca cttctgtttc aaaaagagaa
    38941 tcagattttg ctgcgaacga ttttggtatc acaaaagaaa gagaaaaaaa attctccctt
    39001 tcagagactt tcaaatattc atttgacagt atgatcgtac gaaaaaaaga tgattcagga
    39061 atccactcac ttgaagatct taaagggaaa aaagcagctg gcgaacccaa tactagctat
    39121 atgcgtttag cggaaaaaca cggagctaaa ttagtcacat atgacaatgc cacgaatgat
    39181 cagtatttaa gcgatgtagc aaatggtcga acagatgtta ttctaaatga ttattatctg
    39241 cagaaaatgg ccgtatctgc tttaccagat atccctgtaa aaatactgga gaacgtttat
    39301 ttcaatgaaa acgaaagtgg ttttttattg aaagaaggaa atgatgctct gaaaaagaaa
    39361 atcgatggcg tattaaaaga gatgaaagaa gatgggacga caaagaaaat atctgaaaaa
    39421 tattttcaaa ctgatgtttc agtcaaaccg aaagaaacga tggctgagtc ggtgagtgag
    39481 tgatgtactt tcctctaatt gatttttccc tcatgtggac ttcacttcct ttcgtactgc
    39541 aaggcttggt atacacatta gggattggct tcgtgtcgtt tcttttagga aatctggtag
    39601 ggttgctttt gacagtttta ggtcttttgg attggctgcc tctgaatgta tttattcgtt
    39661 tttatttatc gttctttaga ggcattcccg cactagtcct gctgtttctg ttatattttg
    39721 ggttacctta tcaattaagt gccttaacgg cttcagtcat ctgctttacg attaccagca
    39781 gtgcatttat tggtgaaatc tatcgaggat cactagcagg cgtttcttca ggtcagtggg
    39841 acgctggttt agcttctggt ttttctttct ttggggtatt gaaatatatc gttttgccgc
    39901 aagcttttcg aatctcagta ccggcactca gtaacgtagc tatggatcta gtgaaaggta
    39961 cttcgttagc agcaacaatc acagtgccag aaatatttca aaaagcaaag atcataggcg
    40021 gtcggacatt cgattatttt tctctctata ttttagttgc actgatttat tgggtcattt
    40081 gtatcgggat cgaaaaagtg caacagtatt tagaaaaacg ttctattttt tgtttcttgt
    40141 atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa atatgttcgg
    40201 aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta taccaatatt
    40261 gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac caaggaattg
    40321 tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga tgctatgagc
    40381 tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt ggacattata
    40441 attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc cctacaggaa
    40501 taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc tctggtacat
    40561 ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa gctttgacaa
    40621 accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg gagcgaggcg
    40681 taaaatattt tccaacagat caattgtaca aagaattgaa aagacgttca gaaaatcaag
    40741 atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct agtcaggcaa
    40801 tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat ttgaggcaac
    40861 aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt actatcctta
    40921 tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc gaggattgct
    40981 ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc ttaaaaatgt
    41041 gatcgaatta tttcaaaaaa agcaccatcg aatcgctgtg atccaaaatc cccaagtagg
    41101 acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa atagctctgt
    41161 cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt cacctccagc
    41221 gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga aacagttggc
    41281 aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct ggctgcccga
    41341 aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa gttatgcaga
    41401 taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg gatatattgg
    41461 attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc ctagccgagc
    41521 gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga aacattttgt
    41581 ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag caggagataa
    41641 aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag gaatgattga
    41701 attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga aaaagtggtc
    41761 acttatgcat catttggaac ttattagtca cctgctagat catccaaaag attggcttaa
    41821 atattattca aaagttcagg aactatatga agtgatccaa tgattagata atgtaaatga
    41881 aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa gaagaagtag
    41941 aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa ggctctcctc
    42001 aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt gaaagaaaag
    42061 aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta gtctcaagcg
    42121 tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt ccttatttat
    42181 cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca aaaccgttct
    42241 tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt atcgatactt
    42301 atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact tatcaaggga
    42361 tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc atcaattgac
    42421 tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac aatcatatga
    42481 tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa tttccgaaaa
    42541 tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct ttctgaaact
    42601 cccttcatcg agaggtcgtg acatagcttt tgtcacgacc tctcggctta tcctacgagt
    42661 attattcgat acatttatat caataatcct ttttttattt tatctgcagc ttcttggaac
    42721 gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt caactgtgct
    42781 aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc tccacgtttt
    42841 ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg gactaccgtc
    42901 ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta acaatttcct
    42961 actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg agcatattgg
    43021 tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc agaaacaaaa
    43081 taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta agtaatgatc
    43141 ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc agaaggaccg
    43201 ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca agtgaaaaag
    43261 ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat attataccag
    43321 caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca aaattttcaa
    43381 tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg caccagaaat
    43441 gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa ttgctgttgt
    43501 acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa attcatttgt
    43561 aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg ggattccgct
    43621 gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga tgccgaatat
    43681 cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa gcatagcagc
    43741 aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt ggaaaaatgt
    43801 ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata catagggatt
    43861 tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag tgatcacata
    43921 tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg tagacatagc
    43981 cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct tttttatgga
    44041 aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag attccaattt
    44101 gcccatcccg ttgattttac ttaatcctag accaacagct ttcataaata atggaagaat
    44161 cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca tcaatacgga
    44221 aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt caacaccttg
    44281 cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa ccgctgtacc
    44341 aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca tcacaattag
    44401 tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc ctaatgtgac
    44461 aaataaacca ataataccta ataaataact caaataatca ctcctattcc aaattccgtt
    44521 ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca ttactttttt
    44581 agagtgaaac gcattcattt tccattagaa aataaagcga acaaaataaa aggtttaaaa
    44641 agtgtaacgt cttagtaaag tctataaaaa aacgaaacta tcgattaagc taatagtttc
    44701 gttttcaaca tttataagta aactttttct attggtaata tagattttcg gaagggtaga
    44761 caggtgcgca ggtaatatcg attcctagtt ttttcaatgt ttgttcatca tttttattga
    44821 ccatcacagt agagtgggct tgtgctccct caagttcagc tagtttatca taagcaactt
    44881 gagcgattgg attcgttact gcactgattg ataaagcgat caagacttca ttgatgctta
    44941 gtgcatccaa agaggaatga agtgtctttg atttcaatcc ttgtattgtt tcaagaacta
    45001 atggtgacaa taaaggaatg tcatctgcga tatgggctaa atgttttact gcatttaaga
    45061 taactgccgc tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg acttcatctg
    45121 gtaattcgat tgcaatcaca gcagaaggat cttttgtagg actttgcgct tgaatcttat
    45181 ctgcatagtc atgggcaggg actaccacgt ttcggtcttc aggacgtaaa ccgacttctt
    45241 ccataatcag tttgattcga ttaactgctt cttcgtcgat caatcctttt ttgaagtcgc
    45301 attctgtttg gaaataacga cggatgattt cttgtttaga ggcttcttgg acaacggtat
    45361 catccacgat cccaaatcct acacgattca cacccatgtc agtaggagat tgataaacag
    45421 attctttacc agtaattttt tcaataatac gtttgattac aggaaatgtc tcaacatccc
    45481 gattatagtt cacagctact ttattgtagg catcaaagtg gaaggaatcg atcatattga
    45541 catcttttag atcgactgtg gctgcttcat aagcaatgtt cagcggatgt ttcaacggaa
    45601 cattccatac tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct ttttggcttt
    45661 catgatacag ttggttcaag gaagtagcga gctttccact tcctgggcca ggagctgtca
    45721 ctacaacgat tggtttagtt gtttcaatat actcattttt tccaaaacca tcttctgaga
    45781 cgattttttc tacgttgact ggatagtctt cgatttctga gtgtttatag accttgatgt
    45841 ttcgtctttc tagtttattg ataaagactt tcgtggcagg ctgtccacta tagcgagtga
    45901 taacgacact gttgattaat aagccataac cacgtaattc atcgattaac cgcaagatat
    45961 ccatatcata agtaatccca taatcaccac ggatcttatt acgttcaata tctccagcat
    46021 agacgcaaat cagtatttca gcttgatctt tcaatttttg cagcaatttg attttcgcat
    46081 cttcttcaaa tcctggaagt acacgtttcg catgcttgtc gtcaactagc ttcccaccaa
    46141 attctaaata taatttgtca tagtggttca ctcgttccaa aatatacgct gactgctctt
    46201 caatatattt ttctgaatca aaaccaattt ttttcactag gttccctcct taagtactaa
    46261 agcatttttt catttttttg aggattcgtc aactggaaga gcgaaattcc tcaaaaaaac
    46321 aaagaaaatg gtttaaacca acttgtctag atagttattc attggtatga tagtttttga
    46381 taaggaaggt gctacatgaa aaaaagacag aaaaaggaaa acgcatataa acactatatc
    46441 cgttcgattt ttaccggtta tgaaagaatg cttgaagatc ccgaattgga acaattgacg
    46501 tttacttatc taaacgaaga aacgcagcta actcgtgatg agcatcagcg cattcatttc
    46561 acaacaagag atctgcctag taaataaaaa ataagataaa ggtcatcgga ttcgattctg
    46621 tcctatcaga tggaaagact agttgatcga aaaaaaggct gtaccaaatt ttggtgcagc
    46681 ctgttttatg gagcattgcc cgctcttttt tataacaatt ttttacagaa aatggtacta
    46741 ttgaagtatt aataagtgaa aaacagatga gtaagaggag gcaagtagta tgaaagagcc
    46801 agatacaaat gcaaattatg agccagacga actagaggag acgaatgcgg atcaggatac
    46861 aggacaagaa tcgtcttctt tttacgatat caaagaaaaa gcaagcatga atctttccca
    46921 attattagaa gacttacagg cttttgaaaa agctgtccgc gaagaagata tccctgagat
    46981 ctaccgttta tacaatggcc gattgaatga agaattaaaa agaagctcaa atgaaaatca
    47041 cgagatcgat caattgctga tgcgtaagat ccatgatcgt tttttacagg aatttccttt
    47101 tatggaacaa gtagaaaaca tctcgccaac gatgagctat tacaaaatcg gcacttatta
    47161 ccatgatcgg cccacggtcg gtattgatgc aagtctgcca gaaatttttg ttttgcctaa
    47221 gatcgatgaa gagtgggaga aatattccca accggagtca acggactatg acaaaaaaat
    47281 caatgagcta gacgcaaagg tgatcactgc tcagacagaa attgaacgtt tagatgaaca
    47341 aataaaagaa atcaatcgac aaatgactga tttgaacgac aataaaggat tcttgaatcg
    47401 taaaaaaatc gaggaagaaa ttcaagaatt agagaagaag aagcaagtac tatctaatga
    47461 aaaattaggc tggcttcctt atattgagac gcctgaaaca atccagcagc aaaaagaagc
    47521 attgaagcaa gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa aagaacaaag
    47581 gcaaatcaga cgctatttcg gtagcaaaga gggattcggt caagcaatcc atgaattctt
    47641 gatgaattat cttggcaatg agaatcctaa taatcaatct aatgaaggag gttccgagta
    47701 tgaatgaaca cgatgaagca gaatggacaa aaaatgaaga acaaacagaa gatcatgaag
    47761 aaacgaacac ttcattggaa gaacaaacaa gtaatcctct ggatgacaca gaagaaatcc
    47821 ctatgctaga ggaaacaaaa atacacgaaa aagaaaaagt aactccgacg aatacgaata
    47881 ctgcagaaaa cacccatgct tacgaaataa ctgaaaatcc cgggtattta gaaggaaaag
    47941 agcaagatca tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa ttagcggatt
    48001 tacgtatgag aaaagatttg atcgaatcag attttccaca attattagaa tcatatgatc
    48061 gttttatatt gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg atcgaatact
    48121 tcacgtatga attactgaaa ccgttgaatg atattggtct ggaacggtca aattcagctt
    48181 atgacacatg gaaaacaaga catttttcga tcaattatac gttgaatgga caaaacgaat
    48241 tagtcttttc ctttgtatta ccgaccatcg atcaacgata ccaagtggaa tcgatgagtc
    48301 tcctaaacgt atcaccagag acaatggaaa tcaatgtcca agatgaccgg gtgctttctt
    48361 tgatccgaca ctggtcagtg gatcgagtat tctctgcagg gcagatcacg atattcaatc
    48421 acaaattgaa tcaattatta gcccatgcaa gaacacttgg ttttaccgtt aatcagacat
    48481 tactagacaa tacgaagcca cttcgtttga atcttcagag cgaatttgaa ttgacgaatg
    48541 aagtattgga tgatattttt atcgtggcaa tgaaaaatcc atcctacgat atggaaaaga
    48601 tcaacgaaac tacttatcaa gtacgattag ataaaggaca gtctttaacg ataacaacaa
    48661 acgaaaaaga tcaaacagtc ttgtcgatct catctggaga ctacccacga tctgtcattg
    48721 atttctttat caattacgaa ttcttggtcc cattaatggt gagaaagtcc tgattggata
    48781 agttggatta ccagatgtca ttcagataat tctgttccaa aggacttgcg gcagttatcc
    48841 agaataattg tcacaagtct tttctgtatg tactaaatgg acgtgaataa cttgctgatg
    48901 aaggagggat ttcattagga atgtccacaa ataaaatagc acagcttagc ttattgtctg
    48961 ctgcttgtgt agcaggtagg atcgcttttc aatttattcc gaatttccag ccaatgactg
    49021 ctattttttt atttatagta ctttacttaa gcttaaaaga tgcgttaatt gtcatgagtc
    49081 tttctattgc gatcagcagt ttttattttg gtgttggacc atgggtcatc ggccaatgga
    49141 tcagctatac tgttgttctg agtttgtttt caatcgtctg cttgagaaaa acagtgcaaa
    49201 ggaatctatg gttaaaggga gtctgttttt ttctggcggg catggtttac ggaataggta
    49261 tgaccgtttt tgatacgctg ttatatcgtt tgcctcaacc ttggatctat taccttcaag
    49321 gggtgtcgtt tgatttgatg cacagtatag gcaatgttgt gttctttctt gtttttctgc
    49381 cagtcgtcaa acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat aatttatagt
    49441 ttgcttgcaa tgagtgtcag tatactcatt ttgacaagtt gcagtacaac ctatacacaa
    49501 tcggcttcca accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat cacgttacaa
    49561 gaaaatggtc aaaacttttc ggaaaaagaa gtgttcttca aaaaaggcga tgatttactg
    49621 agtattttga aacgaaattt tgaagtcaaa gaagataacg gcttcatcac ttcgcttgaa
    49681 gggcactcac aggatgagaa aaatcaactc tattggatgt ttactgtgga cgggaaaagt
    49741 gctactactg gtgccaaaga gatcaaattg aatgatggac aatcggtcat tttcaatttg
    49801 tctaaactat aagtttcata aaaaactgtt aaagggcgaa tattgccata attcagtgag
    49861 ttcagttgat gaaagaagga aaataacatg gaaaatttta aaaaaagcgg aatgttttcc
    49921 gtaattgctg ctctaggggc taatattcta gttgctatca gcaaatttgt cggctatgca
    49981 atcagtggca gtgccgccat gctaaacgaa agcatccaca gtatcgttga ttgcagcaat
    50041 cagattttgc tgttattcgg tgataaacaa gccaataaag gacagagcga gttgcatcaa
    50101 tttggtgaag gacgagcaaa atactttttc agtacaatcg tcgcaatgat gcttttcttc
    50161 ggcggtgggg cacttggggt gatggaagct tttgaaaagt tgacgcatcc atcccatgaa
    50221 gtgggtaatc cgatcattgt tatagcaata ctgttatttg gtttggtaat cgaaggaagt
    50281 tcgttacgcg tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact ttccacgatg
    50341 cgctttttgc gcgaaagtcg acacagtgaa atactgatta tttttacgga agacttgtgt
    50401 gctgtaatcg gtttggtctt ggctttagca ggaacaatat tgacttatgc aaccgggatt
    50461 gctgcatttg atgcgatcag cggattgctg atcggtttct tgctgatggg agccgccatt
    50521 ttcctagcaa aagaatttta tagtctgatc atcggtgaaa gcgtgacagc aagcgattta
    50581 tcaaaaatca agttagcttt tgaacgtcct gagatcagtc ggctgatcga tataaaaaca
    50641 gttcatttaa gtccaacgga gattttagtt gcagcaaaag cagatatcgt tggtaacaaa
    50701 gagaatgaag cttactcggt catcaatgat attgaaaaaa atatgcgtca gtctcttcct
    50761 gacaagaaga tgtatatata cattgaaaca gataaatatg acccaaatta ttctcgtaaa
    50821 taaaacgttt attcatgaat tgaagcaaaa atgagaaaaa tataatcttg tttttaaata
    50881 aaacggctac aatttagcga atttatgtta caatgagtcc gctgtttatt tgttgtaatt
    50941 aaaggagata ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc tttgcatgca
    51001 gtgatgccac tttgtataag ctatatacca gtaggattag cttgcggagt attgttgcaa
    51061 aaagttggat ttgatcctct cttatcagga ctgttatcga ttctggtctt ttccggtggc
    51121 gcgcagtttt tagttgcatc tatgcttacg acgcaagcat catttgcaac gacattattg
    51181 atggttttct ttttagaatt acgctataca ttattaggag caagtcttgc cggttttatg
    51241 aaaaaagaaa agcggacgtt tttggctgtc ttttctcaat cactgaatga tgaaaactat
    51301 gcggtgaact acttaaagtt ttcaactgac ccttcctgga ataaaagaaa ggctttatat
    51361 gtcaattggt tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa ttttttcggc
    51421 tcggtgattc gagtagatgc tgaccttgtc cattttgctt tgacggccat gttcattttc
    51481 atgtttatca tgcagatgaa aagcgcacta ctgatcttta caggtttatt ctcaggcgta
    51541 ttaggggtcg tattcatggt attattccaa aatactttcg gattgattgc agcaacagtc
    51601 attgcttcat ttgccggatt tatgctggag aaggcattca aaaaagaaaa agctaagaaa
    51661 ctaagagacc gcggtaaaga tgtcaatgag ccgctcttca acttcccgga acaggaggcc
    51721 aatcaccatg actaaactat atttgctact tttagttgct tgtctgttca tcgtggcata
    51781 tatcccgcgc ttgttcccga tgctttattt tactcatcga aaagtgccat cctggttcag
    51841 tgactggatg aaatatgtac cggtggcatt atttgcggcg ttagctttta aagatgtttt
    51901 cattactcat gaacatctgg atattgcttg gaatatcaaa atagctgcaa tgattctagt
    51961 agcaggcgtg gcttacaaaa cacgttcgat ggcgttgtca gttttgacag gacttgcgtc
    52021 tgtctttttg ctgtctatgc tttaaactgt tttattttat taaaaacaga gattgcgaca
    52081 taagttgttc aaactgatct atccgaactg catttgcaac agtcaattct ggatgcaagt
    52141 ttattcgtag ggataaaaaa gattagtgtt ggcttatgat gcaagctctt ttttatttta
    52201 ggaattagag agggatttgt ccttctatga ttttttgcta taatagggaa gatgtttatt
    52261 ttatgaaaga atagttgagg gaatttaaat gaataaaaaa ttgatgcaag gaacattttg
    52321 gctaaccttt gctaatcttc tatgtaaagt tttaggggta gtctatttga ttccctggct
    52381 aagtatgatg gggaacaatc aagatggtat gcttgctacg acattgtata atgttggcta
    52441 tcttccttat ggattgttcc tgatgcttgg tacagtcgga tttccaaatg cgattgcaaa
    52501 aaaagtagct gtagccacaa aagaaggaga taacgctgct tgtcggctga tttttagaag
    52561 tacgatcaat atcatgtttg tcatcggtat cgcctctgct gcactgatgt atttatttgc
    52621 tcctttacta gccggaatca gtccgattgc taacgttaat aatgggatac tagctatcag
    52681 aagtttatgc ccatctttga ttgctatccc aattcttagt gcaatgagag gatatttcca
    52741 aggaaaaaat gatctgcggc cttatggaac ttctttgatt atcgaacagg ctgtgcgagt
    52801 gatcgttatc ttggctggta cttattactt gcgcgtattg actgacggaa ccatattaga
    52861 agctgtattg atcagtacag tcgcttcttt cttcggtggg ttagctgcga ttatccatat
    52921 gtatatcgtc ggacgcagaa aagacttctt cgaacttaaa gattttttga tttccagccg
    52981 ttatttcgaa agagaaaacc gatctgcctc tgtctctatc attcgggaaa cactaccgtt
    53041 tatttttgtc ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa cgatgaaacc
    53101 actgcttcac tttttccgtc cagagatcgc agatcagcaa ctggaattct tattcagccg
    53161 tgcttctgtc aatccaaata aattgacatt gatcctgatc tccatggtag gaacagtagc
    53221 tataagcagc ttgccaatat taagcacgat gaagaaaaaa gatcggatac aaatcgaaaa
    53281 aacagtagga gatagttttt cgattgcgtt attgattctt cttccttcat tgactggaat
    53341 gtctttatta gctggaccac tatacacatt gttttttggc tatgatcctg aaagtgtcgg
    53401 atatttccaa atggctttgc tagcttcttt gtttttctct ttattcacga tcctatctac
    53461 gatgcttcaa tctttgaatc accatcgttt tgcgatccga ttaactgtag aagcaattat
    53521 cctgaaagtc atcttccaag taatcggatt aggattagtt ggcggatacg ggatgagctt
    53581 atcaaatggc ttagcattcg gtattgtctt tgttcgcggc tatcacttta tgtgcaaaga
    53641 ataccgaata gcacctttag caaagatcag caattttttc ttaaaaactt tccgctccac
    53701 cctgattatg cttgcagtat gttttgccgt tttctttttg ctgaatcagc gattgtcaat
    53761 ggaatcaaaa agctatgcaa tgatttattg tgtggctgta ggaagtattg gcggcttagt
    53821 atttttattt tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg ttaaacatca
    53881 tagcagaagc aaagaatagg ttaactaatc gttttttgct gtcacttgaa aaacggcaac
    53941 tcgtatgatt acgcttgtcg tttttctatt ttccaatttt agtttcatat ctaatcttac
    54001 ttatgatata gttataaggt ctggaaaaat tctttgaaac gaggaaatta aacacatgaa
    54061 acttgcagta gttacagata gttcggcata tctgccggaa cgtatcaaga accatcccga
    54121 cttattcgtt attccaatcc ctttgattat ggatgggaaa atttataacg aaggaatcga
    54181 tatcgaagcg gatgaatatt atggactttt aaaaaacagt aaagattttc ctactacttc
    54241 acaacctgtc gtaggggaag ttttgggttt atatgaggaa ttgaaagaga aagggtatga
    54301 cacgatttta agtatccatc tttcttcagg gatttctggc tttgtcaaca cattatttgc
    54361 gatgaaagat gacatcagcg gagtaacggt cattccttat gactctaaga tcactagtat
    54421 gccgatggga cacatggtag aagctgcctt agacttaaat gatgaaggtc agtcccttga
    54481 tgaaatactt gcacatatcg atcgaatccg agataatacc tacgcttatc tgattgtaga
    54541 tgatttgaac aatttagtac gaggaggacg tttgacaaat ggtgcagcgc tgattggcag
    54601 cttattaaaa atcaaaccga tcctgacatt ttctgaaggg aaaattgttt tattcgaaaa
    54661 aatccgttca agtaaaaaag catttgctcg agctgaagaa attattggta gaagaaataa
    54721 cgaaatacaa ccgccagtca aactttacgt gatacatgca aataatttag aagtagcgat
    54781 tgcggagaaa gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa ttggtcattt
    54841 cggaccagtc attggtacac atttaggtga aaaagccatc ggcattgcca tttcagcgca
    54901 ataattcctt ttattcaaaa aacataccaa aaatattcca acatcatctt ggactttcta
    54961 catgttacta atgagcgtgt aaaagaacga gatggtgttt ttatttctat caatgaagct
    55021 ctttttcttt gcaatcctca cttcaatcct ctataatgtc gcatatagtt tagtaaatga
    55081 gtaaactact aatttactta tttactaaaa ataaaaggat gaggagttaa aataatggaa
    55141 ataccaacaa atttaaaaca taaaccagta atcgttgtag aagactatga taaagttgat
    55201 ggaagaaatg cattaaatac ggatgcaaaa gggctttcac tgggccttgc tcagtggaat
    55261 gatcgtggaa aagtcgatat ctcaggcaag gtatggcgac atactggaga aaaatggtca
    55321 cgacagtcgg aagaattacc aatcacacgt attttagatt tagcgatctt agctgcacaa
    55381 ggaagtttat acttccaaga tgcttatcgt tatgaaaaat tttatgatcc agaaaatcca
    55441 gtcgtagaca tcattggatt acaagggaac cgaatgacgg tagaagtaga taccaaaaat
    55501 ccaaagatcg atgaagacat cattttgtat tacgatacac tacaaaaaga cggagaactg
    55561 attggggaac gattccgtat tttaaaacgt cttttagatg agctaggata ttaatagaca
    55621 gagatgatca aaaggggaag agaagcatgg agaatttctc actaacagaa aaccgaacct
    55681 tttcacggct agaaaagcaa atgatctgga agaaaccgaa aagccatcgg acaagtgcag
    55741 aagaatggcg gatcgcctcc gaaatcaaag ggaattggca agatcctgaa atgaaaatca
    55801 gtaacgtact tttggaagga gatgccgggt cggggaagac acaattagcc aaagcactat
    55861 ctgctgatct gcaacttccc tatacaaaag tgacctgttt tgcagatatg gacaaatcag
    55921 atgttttcgg agccttatta cctgtagtag attctaataa ggaacaagac caagaattac
    55981 tagaagctat ttaccaaaca gatacacttg aagctgtact gacactgatc cagaaccatt
    56041 acggcattga tcctttttct gctaaagaaa aattagcaga gctagttcaa aggatcgaag
    56101 ctgattatcc agatgcaatc cattacagct attacccttc tgaaatcgtt cgagcgattg
    56161 aaaaaggata tttattagag attcaagagc cgactgtcat ccgagatgcc tctgttcttg
    56221 tggcacttaa ctcagcgctc gaaccaaatg ggatgttgaa tttaccgaca ggaatcattc
    56281 gtcgccatcc agattgcgtc attgtgatca ctacaaatcg aaattaccaa ggaaatcgcc
    56341 cattaaatga atctttaaga gatcggatgc aacatgcgga aaaaatggat cttcctgcct
    56401 tagaagtcat ggcagaacgt gcgatggcga aaactatgat ccaaaaacaa gaacttctct
    56461 taaagatggc agagattatc cgtttgttgg atgaaactgc aaaagctaac gccatcaaag
    56521 gtgtagcagg aatgcgttct tatttttatt gggcaaatac ctataagcaa ggacaagatt
    56581 tactccagtc gatttatcca aaagttttgt ataaattatc cactgattca gatgaattgg
    56641 caattcttga acaagctttg tctgacagtg gattgctact ggaacttcag gacatattga
    56701 gaaaagaaaa atggggtcat cctcaatctg agcatacaaa aggaagaacc attagcgccg
    56761 aagaagcaaa tgaacgaaac atcactgaaa atgctgaaga aattctgcgc ttagatgaaa
    56821 agaaatcgtt gtctgctgaa gaaccaaatg agggagaaga gaaacaagaa gaaacaatag
    56881 aaaaaaacga gattcctcct caaatgcaaa aagaacgcag tagcgatatc gaaggaaaaa
    56941 atcaaaaaga acaacaaaca ggagatgatt ctcaagaaat gtctgcttct gacatggaag
    57001 cacatgataa ggaaatcaag aagcaactga ataaagaagc gcgacaaatc atgaaggaaa
    57061 cgattcatga aaaagaaggt ctcatcgttc accgaccagc tttccaagga aaaacgccgg
    57121 aagcacgtga gctacacatg caagtaatgc caatagtaga atcacttagc cggcaaattt
    57181 tagagttact ggataatgaa caaacagaga cgtaccaaaa aggaaaatac gaaggtcagc
    57241 ggttcaatgc aagcaaagta gcatatggtg atttgagaaa ttttgacaaa aagaacccgc
    57301 cacatgagca accttcttta gcggtagctg tacggatcga tgaatctggg tcaatgatac
    57361 gggatgatcg gatcgaagcg gcaaaaaaag cagcgattgc cattgccgaa ttttctaaga
    57421 aagtcgatat cccattgttg atttacggag atacagcaga ccgttcgtca agagaaaaga
    57481 cttctttgtt ttcttataaa gaatttgaag acggatttca atggttaaat gaaaaattag
    57541 tcactatgaa accaaggcaa aacaatcgtg atggtgctgc acttcgttta gcagcagaaa
    57601 aattaaacag acaatccgca acaaccaaac tgttgcttaa tattagtgac ggtcagccaa
    57661 aagcgttgcc ggattataca ggcaaaaaag caaaagaaga tatccagtct gttttgaaag
    57721 aatatgaacg tcaaggaatc ctatttgtct ccgcagctat tggccaagac aaagaagaaa
    57781 tcaagtcgat ctacggtgaa agtcgttttg tagatattac tgacttgaat gaatttccca
    57841 agcaaatgat tcaactgatt gcccgctatc tatgataaaa taaagctcaa cgaacgcact
    57901 tagcagattc gttgagcttt tcgtttctag ttaccggtaa caaggatact tctaaaatag
    57961 aatcggttat aatcaagagg gaccgttaaa ggagtgaaac gatatgatac aagaacaaaa
    58021 atggtggaaa gaagcagtag gctatcaaat ctatcctgct agtttcaaag atagcaatgg
    58081 cgatggtcaa ggagacatca atgggatccg tgaaaaactt aattatttga aagatcttgg
    58141 tatcggcttt atctggatca atccgatcta tcaatctcca tttgtcgata atggttatga
    58201 cgtaagtgac tatcaagata tagaagagag attcggaacg atggaagatt ttgatttatt
    58261 gctaaaagaa gcacatgaat tagggatcaa agtgattatg gatcttgtca tcaaccatag
    58321 ttcggatcag catcaatggt ttgaagaatc gaaaaaatct aaagaaagcc cgtatcgcga
    58381 ttattacatt tgggtcgacg gggtagatgg caaagaaccg aataattgga catcgatttt
    58441 cggcggttct gcttgggagt attctcatga aactggacag tattatctgc atgtttttgc
    58501 aaaagaacaa ccagacttaa attgggaaag cgagaaattg aaagaagaac tattcaatat
    58561 gatccgatgg tggttggata aagggataga tggatttcgt ttagatgcga tttctcatgt
    58621 aaaaaaagat gaatattcag taaaagccac agagaaccct ttctcaccct ttcaaaatgt
    58681 ctcaggaatc gaagaacatt tgaccgattt gaaacatgtt tttgaagagt acgatatcat
    58741 gactgtcgga gaagcaagtg gtgtcactgc agaagaagga ccacaatggg tagggaaaga
    58801 cggttatttc gatatgatat tcgaatttga tcatatccat atctggcagc aagaaaaaga
    58861 agggcaatta gatgtcctta aattgaaact tgcattaagc gcttggcaaa cttcattgga
    58921 tggtatcgga tggaacgctt tatatatgga aaaccatgat gttcctcgtg ccgtttcagt
    58981 gtttggagat actcgtcccg atttttgggc tatgtctgca aaagcaatcg ctatgatgta
    59041 tttctttttg caaggtacgc catttattta tcaaggacag gaaatcggaa tgacgaatat
    59101 gccctttgaa tcgatcgatc aagttgatgc agtagattcg aaaagacttt ataaaaggct
    59161 gcttgcggaa ggtaagacaa gagaagaagc attggatatc attcgtgaaa caacgagaga
    59221 caacagcagg acacccatgc aatggacttc ggaacaatat gctggttttt ctacacatga
    59281 accttggctg atcactaatc caaataccaa aacgatcaat gtagaacaac aagaatatga
    59341 accagagtcg gtcctgcaat tctataagaa catgatccgc attagacaaa ccaataaagg
    59401 tctgatatac ggttcttata aagaatatct tcatgaacat ccacaacttt atgtctatga
    59461 aagatattta gaagatgaac aatatcttat tatggtaaac ttaacagaat cacttgctga
    59521 ctatgaactt ccaaaagaag cagatcagtc ctggacatta ctcttgtcaa attcctctag
    59581 cggagaattt gaagctaaag gcatactagc accttatgaa gctcggttat ataaaacaaa
    59641 caagtaaaac ttcctcgtta aagttcatta gttggacttt gcgaggaagt ttttcagatt
    59701 gctctgtcaa ttactcattt caataattcg ctctaggacc accgatatat ttaggacgag
    59761 agcgaagggc tgtcacgtga gcttgtccaa gggttttcaa acgaggtctg acaggtactt
    59821 ggacatgttt gatatgcata ccgattgatg tgtcaccgat atcgataccg gcttgtccaa
    59881 ctacgtgttc cacttcgaca ggatcattga actggtcaaa agcagcaaca gaacaagcac
    59941 ctccagcatg tagtgcagga acaacagaga caatttcgaa attttttgct tctgccactg
    60001 ttcgttctac tactaatgct cggttcaaat gttcacaacc ttggacagct agcgcaattt
    60061 ctttaggatc caacaactct tttaacgtac ggatgatcca ttgaccaact tccgcactgg
    60121 aattttttcc aatatgtcct ccaacgactt cgcttgtgct gcatcctaaa acaaaaagat
    60181 cacctttttt caagtgtgcc tcagccaata tgtcattaac tatttcagtc aattggtctt
    60241 ttaattcttt ttctgacaac ttcattttct aaaaccttct ttttcaatta atattgcttc
    60301 cgtgcttgaa tacgttgaag acttgcagtt ataggaaagg caagtcccat tccaatcaga
    60361 ttttggaaga tgtttcctgg tatagaagcc actccagccg gccaatcata taaaatccaa
    60421 ccggcgatac catagccgat gatcataact aagcttccta ataaaagccc taatccccac
    60481 atacgagtag aagatttgct gaaagaacca gcaacatatc cttgtaaccc gtggatcact
    60541 aatgaaaaaa ctgcccactg cggatatcct gaaatcaaat cgatcaatag accactggaa
    60601 gcaccaacaa ctaatccacc cgttggacca taaagaaaag cagcggtata gatcccggcc
    60661 tcgcataatg tcacaaatcc attcgtagcc ggtacaggga tcaaaattgt taatgaaagg
    60721 gcaactgtca acgcaatcag catagcatag atcgttaatt gcttagtttt catttctcat
    60781 tcctcctttt tgaataccgc cagaccagac acttccggta tgatcgttca tcagcacgcc
    60841 attagaaata caatgggcaa caaatttttt actttctgct actgctttgg taaaatctgc
    60901 ccctaacaca agattcgctg ttattgcaga agaaaaggca caaccggccc cgtttactgt
    60961 tgtagtgtcg atttttttat gagaaaatac ctcataatga tcaattgaat agagaagatc
    61021 cacagcttca tctccagcca tccttgtgcc gcctttgatc acaatgtttt ttgttcctga
    61081 agcagtgagt tctttagcga gatggatcat ttctgttaac gaagagggaa gagcttgacc
    61141 agaaagtaaa gcagcttctg ccaaattagg cgtaatcatc gtaacaagtg gaaaaagttc
    61201 ttcgatgagc tgcgaaatat acaattgatt gatcacagct tcagtttctt tgaatgccaa
    61261 aacagggtct aaaatgattg ggatattttg ttttgttttt atgaagtctc gaacaaccat
    61321 gattgcttca cttgaattca ataacccaat tttgatacca tctaatgaag tcattttatc
    61381 aatcgaaact aactgtcgtt taagcaattc caaagatata gattccagca taaatcgctc
    61441 attaatatct agtgccccta tagaagtcaa ggcgcttagt ccgaatagac caaaattctc
    61501 aaaagttttt aaatctgttt ggattcctcc accagcaaat ggatcagaac cgccaattgt
    61561 caagattctt ttcataacat tttcctccat gaataagagt ataacgaaat tttcaaaaaa
    61621 gaaaaacagc caattggcat atttttatct catccaattt aaaaaaacaa aaagaaaaga
    61681 aagaccaaaa tggatctttc tttccttaaa tagttaggac ttttgtgatt ttaattcttt
    61741 ctcgatttga agccgttgca ctttcattgt agctgttcgc gggattgcat caaaatcacg
    61801 gatgataggg acgttcaagc gaggaagttc atggacttgc tcccaccatc gattccaatc
    61861 catttcttta tcaggagcta aagcaataat cggttgtgga gaatgatttt tatcccttac
    61921 aatcactact tctgccaaaa aatctaacga atctaataaa aagtcttcaa tagctaatgt
    61981 actattgatc gtttcgatca aatccacttg ccgatctttc aaaaataggt ggccatgctt
    62041 atccataaaa ccgtaatctc cgctatccca ccaatcgcca taaacatttt cctggaaccg
    62101 tgcatcttcc ttgtaataag tcaaagcccg tcctttagac agtaattgta tatgaccatc
    62161 tgtgttttca ggtaggacat tcccaactga atctgtaatc cgagcgcttg tcatgtcttc
    62221 cagtccaacg cccatatctc ttgcatcact tgttttcaaa ctctctagtg tatgagcctt
    62281 aagaatcatt ggtccgcatt cactttggcc atatacttga agaaataccg catcctgtgc
    62341 catcgacgtt cgcaaaaatg tcttcattgt ctggttgttt atagcatcaa aagtggagtg
    62401 atagtatcgg atacccgaaa aagcttctgg atgctcctta gcagtaaaac gccactgaac
    62461 aaagttattc ggatgggtct ctagtgcaat tggccggtga gcttccaaca tatgaacaac
    62521 ttttgaactt tgtgcgtttg ctaaaggcat cataggaaat cccatggaca tcaaagaaga
    62581 gataccaata ttgaatctgg aatgcactgg agagatgtga aaagcgatta atttcttttc
    62641 cgaaattttt gtgaaaactg ttttttgcca tttcgtccgc catcccatag aatgagcaga
    62701 atgacaaata agtttaggga taccagttgt accagaagta tgggtcatat aagaaatttc
    62761 atttttgtct aaaaatgatt gagaaacaga caaagcaggt tgttccatta aataaagaat
    62821 aggaa
//
LOCUS       DAFEML010000009        61540 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFEML010000009
VERSION     DAFEML010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.009"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="LP468_000684"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="LP468_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL2080243.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2945..3379)
                     /locus_tag="LP468_000685"
     CDS             complement(2945..3379)
                     /locus_tag="LP468_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080244.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3396..4601)
                     /locus_tag="LP468_000686"
     CDS             complement(3396..4601)
                     /locus_tag="LP468_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBL2080245.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5295..5681
                     /locus_tag="LP468_000687"
     CDS             5295..5681
                     /locus_tag="LP468_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2080246.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5775..5966
                     /locus_tag="LP468_000688"
     CDS             5775..5966
                     /locus_tag="LP468_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080247.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6480..6812
                     /locus_tag="LP468_000689"
     CDS             6480..6812
                     /locus_tag="LP468_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2080248.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7108..7263
                     /locus_tag="LP468_000690"
     CDS             7108..7263
                     /locus_tag="LP468_000690"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL2080249.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7539..8879
                     /locus_tag="LP468_000691"
                     /pseudo
     CDS             7539..8879
                     /locus_tag="LP468_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9120..10736)
                     /locus_tag="LP468_000692"
     CDS             complement(9120..10736)
                     /locus_tag="LP468_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2080250.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEEIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10854..11072
                     /locus_tag="LP468_000693"
     CDS             10854..11072
                     /locus_tag="LP468_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080251.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11267..11728
                     /locus_tag="LP468_000694"
     CDS             11267..11728
                     /locus_tag="LP468_000694"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2080252.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11921..12160)
                     /locus_tag="LP468_000695"
     CDS             complement(11921..12160)
                     /locus_tag="LP468_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080253.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12184..13707)
                     /locus_tag="LP468_000696"
     CDS             complement(12184..13707)
                     /locus_tag="LP468_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2080254.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13725..13847)
                     /locus_tag="LP468_000697"
     CDS             complement(13725..13847)
                     /locus_tag="LP468_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2080255.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13877..14860)
                     /locus_tag="LP468_000698"
     CDS             complement(13877..14860)
                     /locus_tag="LP468_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL2080256.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14884..15033)
                     /gene="rpmG"
                     /locus_tag="LP468_000699"
     CDS             complement(14884..15033)
                     /gene="rpmG"
                     /locus_tag="LP468_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2080257.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15054..15431)
                     /locus_tag="LP468_000700"
     CDS             complement(15054..15431)
                     /locus_tag="LP468_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080258.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15463..15642)
                     /gene="rpmF"
                     /locus_tag="LP468_000701"
     CDS             complement(15463..15642)
                     /gene="rpmF"
                     /locus_tag="LP468_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2080259.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15657..15926)
                     /gene="rpsN"
                     /locus_tag="LP468_000702"
     CDS             complement(15657..15926)
                     /gene="rpsN"
                     /locus_tag="LP468_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2080260.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16449..18215)
                     /locus_tag="LP468_000703"
     CDS             complement(16449..18215)
                     /locus_tag="LP468_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080261.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18175..19929)
                     /locus_tag="LP468_000704"
     CDS             complement(18175..19929)
                     /locus_tag="LP468_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080262.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20039..20608)
                     /locus_tag="LP468_000705"
     CDS             complement(20039..20608)
                     /locus_tag="LP468_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL2080263.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20626..22041)
                     /locus_tag="LP468_000706"
     CDS             complement(20626..22041)
                     /locus_tag="LP468_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2080264.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22052..22720)
                     /locus_tag="LP468_000707"
     CDS             complement(22052..22720)
                     /locus_tag="LP468_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2080265.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22850..23434)
                     /locus_tag="LP468_000708"
     CDS             complement(22850..23434)
                     /locus_tag="LP468_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2080266.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23765..23998)
                     /locus_tag="LP468_000709"
     CDS             complement(23765..23998)
                     /locus_tag="LP468_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL2080267.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24013..24963)
                     /locus_tag="LP468_000710"
     CDS             complement(24013..24963)
                     /locus_tag="LP468_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2080268.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24960..25802)
                     /locus_tag="LP468_000711"
     CDS             complement(24960..25802)
                     /locus_tag="LP468_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2080269.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25804..26523)
                     /locus_tag="LP468_000712"
     CDS             complement(25804..26523)
                     /locus_tag="LP468_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2080270.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27215..27373
                     /locus_tag="LP468_000713"
     CDS             27215..27373
                     /locus_tag="LP468_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080271.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27445..28671
                     /locus_tag="LP468_000714"
     CDS             27445..28671
                     /locus_tag="LP468_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2080272.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28759..29151)
                     /gene="rpsI"
                     /locus_tag="LP468_000715"
     CDS             complement(28759..29151)
                     /gene="rpsI"
                     /locus_tag="LP468_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2080273.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29167..29610)
                     /gene="rplM"
                     /locus_tag="LP468_000716"
     CDS             complement(29167..29610)
                     /gene="rplM"
                     /locus_tag="LP468_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL2080274.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30129..30596)
                     /locus_tag="LP468_000717"
     CDS             complement(30129..30596)
                     /locus_tag="LP468_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL2080275.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30716..32254)
                     /locus_tag="LP468_000718"
     CDS             complement(30716..32254)
                     /locus_tag="LP468_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL2080276.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32334..33020
                     /locus_tag="LP468_000719"
     CDS             32334..33020
                     /locus_tag="LP468_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL2080277.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33221..33748)
                     /gene="msrA"
                     /locus_tag="LP468_000720"
     CDS             complement(33221..33748)
                     /gene="msrA"
                     /locus_tag="LP468_000720"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2080278.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33832..34509)
                     /gene="pgmB"
                     /locus_tag="LP468_000721"
     CDS             complement(33832..34509)
                     /gene="pgmB"
                     /locus_tag="LP468_000721"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2080279.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34506..35636)
                     /locus_tag="LP468_000722"
     CDS             complement(34506..35636)
                     /locus_tag="LP468_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2080280.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35636..37819)
                     /locus_tag="LP468_000723"
     CDS             complement(35636..37819)
                     /locus_tag="LP468_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2080281.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKGIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37816..38841)
                     /locus_tag="LP468_000724"
     CDS             complement(37816..38841)
                     /locus_tag="LP468_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2080282.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38886..39713)
                     /locus_tag="LP468_000725"
     CDS             complement(38886..39713)
                     /locus_tag="LP468_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2080283.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39710..40777)
                     /locus_tag="LP468_000726"
     CDS             complement(39710..40777)
                     /locus_tag="LP468_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL2080284.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40803..41639)
                     /locus_tag="LP468_000727"
     CDS             complement(40803..41639)
                     /locus_tag="LP468_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080285.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41636..42505)
                     /locus_tag="LP468_000728"
     CDS             complement(41636..42505)
                     /locus_tag="LP468_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080286.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42575..43858)
                     /locus_tag="LP468_000729"
     CDS             complement(42575..43858)
                     /locus_tag="LP468_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2080287.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43872..45557)
                     /locus_tag="LP468_000730"
     CDS             complement(43872..45557)
                     /locus_tag="LP468_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL2080288.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45832..46857
                     /locus_tag="LP468_000731"
     CDS             45832..46857
                     /locus_tag="LP468_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080289.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47452..51126)
                     /gene="rpoC"
                     /locus_tag="LP468_000732"
     CDS             complement(47452..51126)
                     /gene="rpoC"
                     /locus_tag="LP468_000732"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL2080290.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(51184..54801)
                     /gene="rpoB"
                     /locus_tag="LP468_000733"
     CDS             complement(51184..54801)
                     /gene="rpoB"
                     /locus_tag="LP468_000733"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2080291.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55529..56497
                     /locus_tag="LP468_000734"
     CDS             55529..56497
                     /locus_tag="LP468_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080292.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56515..57420
                     /locus_tag="LP468_000735"
     CDS             56515..57420
                     /locus_tag="LP468_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080293.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57417..58223
                     /locus_tag="LP468_000736"
     CDS             57417..58223
                     /locus_tag="LP468_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2080294.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58359..59348
                     /locus_tag="LP468_000737"
     CDS             58359..59348
                     /locus_tag="LP468_000737"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL2080295.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59665..60189)
                     /locus_tag="LP468_000738"
     CDS             complement(59665..60189)
                     /locus_tag="LP468_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL2080296.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60476..>61540
                     /gene="scm"
                     /locus_tag="LP468_000739"
     CDS             60476..>61540
                     /gene="scm"
                     /locus_tag="LP468_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL2080297.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        18669 a        12350 c        10307 g        20214 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa aagtacattt cttcatgttt ttttcggata tttgtgcttt ttaaccattc
     2521 agcagctgaa aacatataaa aagatatgta tgtattcttt ctgaaattaa gttcatttct
     2581 atgcgatgaa gcatgttttc aaaatattac cctttcttag attaaacttc agagtattca
     2641 aataacggaa taaggagcct tatcccgcat tactgaatga gactgtgaca taagtaaaaa
     2701 ggtgacttca aattccttct tcggaatttg aaatcacctt ctttataatt ataaagtatc
     2761 ggtttcacag catttctgaa tgattcctag aatcttaaac gaatgattgg agttatcaac
     2821 attttttcac tcgtttttag cgaaacaaaa aatgacattt gtcacagcct cattaaatta
     2881 ttgattcttt ttctttataa ttgaattgtc catatttaaa gtgtctagta ctctacatga
     2941 ataattaatt gctttcactc aaatacttat aatctattaa cttgtagttg tttaactttt
     3001 ctgaaaaagt tagacccacg taataatctt cccagctttc tctttcaatt aactgatcca
     3061 atttttgata atccataaat tcatcatgta tcaaaaagaa taaataactt gatattttag
     3121 catctagctt aatcagatta aataatgttt gtttaaaatt gctaccatta atatgactga
     3181 tagattctct agcttcttca cataaacttt ttactttatt aattactact ttgtcatatt
     3241 catttaacac actattatta ccattactta gacgctcaga ttctacgaaa caactcaaat
     3301 cagaaatttc ccaaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3361 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattgtcc
     3421 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3481 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3541 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3601 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3661 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3721 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3781 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3841 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3901 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     3961 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     4021 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4081 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagattttct
     4141 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4201 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4261 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4321 aaaactttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4381 atgtatagaa gaaacatctc attaaaatca ccagtaaaga aatggaaatc tttagttttt
     4441 ttaatattat cagttagtaa ctttttataa tcataaaaaa aataagtagt tctatctgag
     4501 cgatactctt ttataatact gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa
     4561 acatgaagag actttaataa gacttcttta tctgaaaaca cttttgtttc tctctttcct
     4621 ttctacatca ttaaatagta ttttatacgt tatctaaaat actattcctc tgtcaaaata
     4681 agctaactta cttcattata aaatatccac ttatcgcttt catgtatatt ccaccgtaaa
     4741 aagtacattt tatcaccgag aactcatcat ttttcatcat gatgaatact atttacatat
     4801 atctagttca aagacaataa ttattatgat ccgttattat ctaagcacta tacagataat
     4861 aggaattttt cgtttctaaa tattccaatt tgggaatcca ataaaaattt tcgttcaaat
     4921 acgtgtctat tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata
     4981 caatctatac acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac
     5041 gtaaaaagct caagacattt tcttagccat aaggacatgt ttgatattta agaagatata
     5101 tgaattttct tttctaagta taaagataac tatccattat caactaaaaa aacatttttg
     5161 aaaataaaca tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca
     5221 gcataattgc attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg
     5281 aggaggtgtg caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct
     5341 ttgaaaaggt cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa
     5401 aacatgaaca acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta
     5461 aacaaccgat taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa
     5521 tccttccttt gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttgata
     5581 aaactgataa agaaattgga aaggttctgg ggattacaag acagggtgcg acaaatttaa
     5641 aacatcgact ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat
     5701 tttgtatgct tctttgctcg ttctcctcct tcccaaagaa atagattata agtccatggg
     5761 aagaaggtag atttatgaat tctttaaaag aagatttcat tttagcaaag gctggaaatg
     5821 aagaagctgt tgaggcaatt ctcaaaagat ttagctcttt gattcataag caatcctgga
     5881 gaactggaaa atatgatcaa gattgttatc aagaatgtat gcttgcaata tatctagcta
     5941 tctcgaaatt cgaaattaaa gaataactca actaagggag tctgtgacat aagtaaaaag
     6001 atagtttcaa atttcgaaca ataaatttga aactatcttc tttataatta taaagtatcg
     6061 attttacagc gttctataat gattcataga atctaaaacg aatgatttta attatcaacg
     6121 ttttttaatt cgtttttagc ttaaaaataa cttttgtcac agtctcactc ctaaaattac
     6181 tttatttacg tatgaagtgg gcaggaggtc gaatccagaa ctgggctatg gtacttcaac
     6241 gaggacttct cctctagaat tgaaaagcat gcgatttacc ttccgtaacg acggtagatt
     6301 tattcaacta tgtgtccaat caaaatttgt ctgatttcaa aaatagtcaa gagaattttg
     6361 gttgttaaaa actcttatct atcaacttcc acagtttagt tgacaaaccc tgatactaag
     6421 ttgggctatg atacactttt cttgactatc agttacgtta ccggaaggaa tgaactctat
     6481 tgagaaaaac atatgatcgt aaatttaaac taaagatttc acaggatatc cttgagaaaa
     6541 aagtaactac caagaaaatt gctgaagaat acaatatctc tcgtccaaca atttcccgat
     6601 gggtttcaga atatcgtcga tacgggaaaa atgcttttgc tggacaagga aaaagattac
     6661 ctgataaagc agatttctac attcttgaac aggaaaataa acgactaaaa gaggaagacg
     6721 agtgttctac gaacacaaag atcgatacgg atctccaggg atcactcaaa aactttacga
     6781 tgaaggaatc gaaatcaata aacgtgttgt agctgttctt atgcgtgaaa tgaatttatg
     6841 cacaagagga tttcatcgac gcaaatcttc tcatggtaga gaaaaaacaa tcaaagaaat
     6901 ggtaaaaaaa tgttgaatcg ataatttgaa cagaaccaaa ttgatgctgt ttgggtgatg
     6961 gatattactt acattccatg taatgacggt cgcctctatt tgtccaccta tattgactta
     7021 gcaactcgta ttctacgtta ctatatggta gattcacaca tgaaaaaaga gattgtcgtc
     7081 cgtccattac aaatttatta aggagaattg cctacggtaa ttcattccga tagaggtagc
     7141 cagcatcggt cttttattta tcaagagctg ttgaacgacc accacatcac acattcagtg
     7201 agccaaactg ggactcctgt tgacaatgca gtaattgaag cgtttcatcg atcaatcaaa
     7261 tgagaattaa tcgactccaa caaatataaa agtaaaatag agatgaaggt gttaatccaa
     7321 gattatttag aagactacta cccaaacaaa agaatccata caaaatttat gatgactcct
     7381 tgacaatttg aagcgaagaa aataagggat ctataatatc tagtgttggt gacgccttct
     7441 gttgccaata ctttttcttt tttctaataa acgcaaacag acaccttaaa atcctttaga
     7501 ataaagtcga cgaaaaccat tcaaaggagt gtttcaagat gtcctattca gagtttacca
     7561 aagagttact agatattcta gacctaaatc ttatctttca tgaagatgcc tttcgcaaag
     7621 agcgaatcaa tgacgaaaca tgttttgttt ttgatggcac attgacctat caaccggagg
     7681 aatgctttca tcgccactat caaaatgaac aaacgatcat taaatagggc tggaaaaaag
     7741 tatccatctt attgaatgat gtcagtaact acaagaccat tctgcggatt aacaaacagc
     7801 gcttcaaatg taaacactgt ggaaagactt ttttagcaga agattcagtt agtgatcgtc
     7861 gctgctccat tgctcgcaga gtcaaacaag ccattcttga gctattaagc gaacctcttt
     7921 ctatgtcttt gatcgcacgt atgaagcaca tttctccgac cactgtcatt cgaatacttc
     7981 gcagccttcg gcctaaaacc atttctttga gccagctgtt accagaagtg gtgtgtttcg
     8041 atgaattcaa atcagtgaaa aatgtctcgg gagccatgag ctttgtcatg atggacggca
     8101 agacccatca actgattgat attgtggaaa atcggcaact caatccttta cgcgactatt
     8161 tcttgcgcta ccctataaaa gtccgtgaac aagtgcgtct agtggtttca gatttctata
     8221 caccctatcg cacattggtg aaagagtgtt ttccgaatgc ccgaatcgtc gccgatcgct
     8281 ttcatattag ccaacacatt ggtcgggctt ttaccaacca ccgaattcaa gtaatgaaga
     8341 cctttaaaaa aggggatcgt cggtcgaagc acttaaagaa atactggaaa ctacttcaaa
     8401 agaatgcgtg ggaattgaaa ggtcagcatc gctactggcg tccgtcattt cgagatcatc
     8461 tgacagaagc agagatagtc gatcggctat tatcttatga tgattcctta aagcgaggct
     8521 acgaagtcta ccaggatttt ctttccgtta tcagaagaca agatgttcct gaattcgtcg
     8581 cgctcctaaa agaagactac aaggagttgc cagagcacta ccaaccagtg ttcacgacct
     8641 tcaagaaata ccaaacagaa atcaaacgag cgttgcgcgt tccctattcc aacggcccta
     8701 tagaatgttt gaataaccat atcaaagtac taaaacgaat tgcctatggc tatagaaact
     8761 ttcaaaacta ccgagaacga atctttttat atcgaggaaa atattttaag aaaactaaga
     8821 atactaccca actgactaaa gccagaacaa caacacggct agacaagata gctgtctagc
     8881 cgtgtgagta tctcgattat tctattgaat ttcttcacca acactcattg acgaagagcc
     8941 aaaataagta atctaaccga ctgttaacta aaccattgca ggtcccgtta aagatacttg
     9001 tgcctgttgt caccgcttct ttttcttgtc cacaagcgct taacacactt aataaagccc
     9061 ctgctattat taataataat atctttttct tattaaaaac ctcctcatct atttccagat
     9121 tagtaaatgt agtaatctgt gctttctttt ttctcaatac taataactaa cttatggggt
     9181 aaacaaatac tcgtttgacc gggttttgag atccatccag ttctaaccgc gatttgatca
     9241 ggactattat cttctttaac tcgaattctt ccatctttaa tctcaacaat attatattgt
     9301 cccttcgcag gatgataatt cacgagttta tgattgatct tatccaaatc gaagcgatcc
     9361 atttccttgc catcaattcg aacgatggca tatttgatag catcttcagt tgtttcattc
     9421 tccttttcta tagagaatac aaataaggga ataaaagagg taataatcaa aatgccaata
     9481 attatgacat cgcctatctt gacaccagct tttcttaaaa atttcattaa cgatatctgg
     9541 ctaaacatat tagacttttt ccatggaaat ggtgaaattt ttcggaaatt atctgcatta
     9601 agagaatcag ttaaacaacc ctcaagttgt tccttaatac attgttgatc catcttcata
     9661 ccaataaaaa ctagtttatt aatgcgttca ccaaacaacg gatgccaggc ttccttcaat
     9721 tcgggatttt tttgtataat catttgacac tcaattttag gtaaactagc tacccaataa
     9781 tttaatgatt caatactttt atagctaccc gatgtttcaa agatcgtcga aaaatcacta
     9841 tgttgggcaa accaaagaaa cccttttgct cttgtaatat tgccaggaaa atttttatcc
     9901 gtaagatggg caaatttttg tgcgtcaagg agtaaccgat ttcgatagat aaaacttgag
     9961 ataccatatt cttctgtttc aggaatatga ttttgatagc caagctctaa ctctttgaac
    10021 cagcccactg aataggaagt ctcatctata ttaaaaagat ttgtatttag aattttcgat
    10081 aagtctactt cacctttaat tgtcctaatt attttggcat tggactgtaa cttagcaatt
    10141 agaccgttaa ttttgtaaat cgtcttggtt gacactaagt cactattatt taaaagtaat
    10201 atgttacaac actcgaattg atcaattaac aagccacgaa tatcctgttc ttcttcaact
    10261 acattacctt cagcttttct ttcctgaatc tcttcacccg tttcgaaatt atcccaaaaa
    10321 cgttttacat ccactactat aataatggca ccaatctcta atcgttgggt caaatcaatg
    10381 tctaaagggt ttttagctaa tataattgct tgaataattg gaattggttt gctgattcct
    10441 gaagcttcaa taacaatttg attcaagtca gaaaattgca ctaattgatc tagttcaaca
    10501 atcaaatctt cgcgtaatgt acaacaaatg catccattcg gcatcgaaac aagtttttct
    10561 ccagttcttt taaaaccttt cttgtcgact aataccccat caacatttac ttcccctatg
    10621 tcatttacaa tgacagcaat ttcctttccg tgatcaccgt acagaatatg atttagaagt
    10681 atcgtttttc ctgaaccaag atagccagtt aagattgtaa taggtatttt tttcataggg
    10741 aacctctttc tataccttga atttacactt taagtgcaac acataaaaat gagtcataat
    10801 cgatatccaa ctagtataag tttgtcgaga acactcctag aaggaaaata attatgagcc
    10861 agtatcgtca tcttactata ctcgaacgag aaagaatctt tctgcttcac gaagaaggat
    10921 tttctattag tataattggc aacgacattc agcatagccc gtttactatt ttacatgaac
    10981 tgagaagaaa caagaaaaaa actattcacc ttccaaagcg gaaaaaaatt atgcttatcg
    11041 aagaaaaaaa tgcggacgtt atcacattct aaatgatccg tgagtttggt caattgttcg
    11101 tcatttattt gtcgattttc agtggtcgcc agaggaaatc tcgaatcgtt tgaagcatga
    11161 acatatggac ttttcaatta gttttatcac gatctaacgt gcaatttgca atgatctttt
    11221 cgatacagaa cccctctcac acggcaataa aggcctgatc cgttcattgc accatcgagg
    11281 aaaaacaaga catacaaaaa atcatgtcga gtctcgtgga aagatttgcc ttactcattc
    11341 gatccatggc cgtccaaaat ccgcagatga tagaagtgat tttggtcatt ggaaagccga
    11401 tattgtagct ggcaaaactg gtggtacttg tttagtgact ttgacagaca gaaaatcatg
    11461 cttcctttta gcaggaaaga aggtccccag aaagaaagcc gcttatgtga gcgagaaaat
    11521 gattgaactt ttaagcagta ttccaaatga ggcggtcaaa acgatcactc cagatagagg
    11581 aaaagaattc tccaatcatt tcgcagttac agaagcattg aataatatgc ccttttattt
    11641 tccagatcct catgcccttg gcaacaatga acaaattaaa atacgaatag actcattcga
    11701 gaatacttgc caaaatcgaa agagatagct acggtagata actcaacgat aaatcagatg
    11761 attgaaaaac tgaataacag acctagaaag tgtttagatt ggagaacacc ttatgaagtc
    11821 ttctttgata aagtgttgcg cttgatttga caattcaaga cataataaaa agcagatcaa
    11881 atccaaataa gggaaaaatg atctactctg gtattatcaa ttaattggcc aagctattat
    11941 gccgttttgc taaacgtcta cttcttccag tattgacctt gataaaacaa caatcaggat
    12001 cccgttttaa tactctatga actgtgtcaa tactaacatg taaagttgca gcaatatcag
    12061 ctaatgtact cccatttaat ctcatttgct ttgcaaatcg ataacgccga taagcatcaa
    12121 tattcttgga atccatagac aataatactt ttcttaccat gtatttcctc caaaaattga
    12181 attttaatga gccatcattt cttgagcaat ttcatgttta gacaatgaag ctggatagaa
    12241 agtaggccaa ttatgcaatt cattatagag tttttcttga ctttctccac caaagaaaat
    12301 atggaaatgc tctgccttac ttggtgcaat tccatgatca ctaaattgaa tatatttaaa
    12361 acgaccagca cctgcatcat cagtttcaaa attaaaacga acaccacggt ttcctttttc
    12421 ataattcaaa attttgtatc caacatattt gtatgtgtat tgatgatgtt caccgttgac
    12481 tacaaaatca atggtgttgt ctttaatgtt gatagtatca atatctgtct tatagccagt
    12541 agtataataa tctttgtact cggcagctgt catgtcttta ttgatttttg ctttgtaatc
    12601 gaaaacttca tccaaaattc catcttttaa caacggataa acagattgcc attcgcctgt
    12661 ataatcactc aattcgcgat ccttcacatc ggcatcttta aagtacccat tagcaactgt
    12721 cttttcatcc ttcgcttctt tttctggaac tacctcttca ccagcaacca tagttgtttt
    12781 ttctaacgct tttagattgt cttccattac tgaaacataa tcttcaccat tatccatttg
    12841 ttcttttgta agactttcaa gaggattcag tacttccaat tttatcccag cttcgttggc
    12901 caaagttttt gcaattttat cattagcatt cttttcaaag taaatataat tgatcttatt
    12961 ttttttaaca tactctttta attcagctaa tcgaccagaa gatggctctt cttcaggact
    13021 tagtccagca ataggaactt gtttcaatcc ataatccaaa gctaaatatc caaaggctgc
    13081 gtgttgcgtc acaaaacttt tttgtttcgc ttctttaaga ctagtggtat agtcagcatc
    13141 caaccgtttc agtttagtca aatacttttc agcatttgtc tcaaatactt ttgctttttt
    13201 cggatacaat ttaactaact gatccttgat atttgaaact tccttaattg ccattttggg
    13261 tgaaacccac gtatgaggat ctagttcatg atggtgatct tcttctccgt gatcatgatc
    13321 ttcttcttca ctacctggca ataaaatcat gtcttttgtt ccttctacta cattaggccc
    13381 agctttcttc caactttctt tagcttttgg tacccatgat tccatgtttt cgttatgata
    13441 tacaaaaaca tcagcatcat gagcttttgc catatcctta gctgagggct catagtcatg
    13501 aggttctgat cccgctggaa ccattaaatc cacgttcgct tcatcgccga cgatgttttt
    13561 ggtgaaatca tacattggat agaatgttgt tacaatttct aattttccat ctttatcatt
    13621 cgatactttt gcatcattag tgctggagca agctcccaat aatcctagag ctgctatccc
    13681 aataagtcct acactgattt tcttcattct ttttccttcc ttaattatgc taatttcttc
    13741 attttatttc gtttatgttc tttgataatt tttaatgccc tttttctagt tttaatattc
    13801 gggcttttaa gtcgtcgata tgcactagat atatccgttt tctccattag aaattacccc
    13861 caatcactac ttatcattat ttgctttccg ccagtaattt atcaaaactc tgtttgatcc
    13921 tttcttcatc caacattttt ccgattagaa taatagtggt ttggtctttt tgtcgagtgg
    13981 tgtattgaaa attaacctgt tcgtttacct cttgcatggc aactataaaa tcctgctctt
    14041 gtaaagcaat caatccttta aaacgataca ggctcccttg gttggttaaa atcagccagt
    14101 caatccattg gagtaaaaaa tcttttttta tgtcttgatc tgaagttaag agaattgatt
    14161 taaactcatg tacttgatgg tgttgatgat agtatttgcc attatagtga ttttctgatg
    14221 aatcactttc aaaaactaag ggatgattaa attttttcaa attataaaaa tccttttttt
    14281 gaatcgtttc actatgtgtg aacattcgaa tatcggataa agggttaata cttttgattt
    14341 ctctctgtaa tttttttagt gcagataaat tcaagttttg ttttctagac acaaaaatgc
    14401 gatctgccat gacaagttgc ttaagggctt gtggttctct ttcaataagt tcaaaactgt
    14461 cactatcaat aacagtcaat aaactatcga tatatactct tcctcttagt tgaggcgctg
    14521 ttaaaagtgt ttgaatgatt ggttggggat ctgctatacc tgtagtttca atgatgattt
    14581 gtgaaattgg ttgttgatgt tcttctattg tttccagtaa agaaatcaat attgctaata
    14641 aatcactgcg aagactgcaa cacatacatc cattatttag ttgtaacacc cgttcctcgc
    14701 tatgaactaa taatttgtga tcaatcccaa cttcaccaaa ctcattttca attataataa
    14761 tttcttccct ggggtagggt gagacttgca aggcttgatt gattagcgtt gtttttccag
    14821 cccctaaaaa cccagaaacg attgtaactg gtatgcccat tttgtcacct ttttaccact
    14881 tagctatttc acttctttaa aaattgcccg tctgcgcaat tttggcgaat acttttttaa
    14941 ttctaaccgt tcagggttat tccgtttatt tttgctggtg agatacagac gttctccagt
    15001 ttcgacacat tccaaaataa tattttgacg cataaatctt cctccttcaa tacttatcga
    15061 tcttcaagat atgcttgaat ttgttgtgca tcttcaaaag ttaactcgcc agattccaat
    15121 tgtgaaacta aattttcttt catatcaaca ggtatctccc aataaccatc gatacattga
    15181 aataactcct cgtcatactc ttcaaaaatt ggatagattc ttaaaaaatc atcaaatgat
    15241 aagccttggt cctcatagta atctttgact aatccatttt caattgcctg ttgggtcggt
    15301 aaacccgttt cagtaataat tcctctctct accatcgaac gataaaaagt gcatttatct
    15361 agcgattgct gggtcgtttc aagataatac tttaatcctt cttcaactaa aggtgggtaa
    15421 ataatttcca ttttgattcc ctcctaaaag ttatatatta aactattttg aagctccttt
    15481 aattactttc tttccattat agtacccttt taaagataca tgatggctac gtctataatc
    15541 accattcgct tcgtcaaatg aaatttctgg ttttactaca gtttgatgag ttcttcttaa
    15601 ccgtttcttc gccttagatg tttttcttgc tggtactgcc atgatatttc ctccttttac
    15661 caacttgctt tttttactcc aggaatcaac ccttgatggg caagttctct aaacttaata
    15721 cgggacatac cgaactttcg catataccct cttggacgac catccgtctg atcacgaagc
    15781 ctcagacgat tcggatttga atctcttggc aatttagcga gagcggtgcg atctcctgcg
    15841 gcttttaatt cctgacgttt atctgcatac ttttcaatca tcgccatttg tttctttgct
    15901 ttagcaattt tcgacttttt tgccatatac ctttatactc cttttatttt gatttagaca
    15961 cctcaaatcg taatcgttac gttttgacac tgatacttta ccaacaagag ttgctcttgt
    16021 caacaataaa taacatgaaa taaaactcat atgaatagat aactatttga aaacgaattt
    16081 atcggtacat agagataatc aaatcattta aaagaatatg cagtttaggc tctgaaaaat
    16141 aagaattcac ttttattagt ccaatcaaac acaaataccg ttttaagtag cttttcctct
    16201 acttaaaacg gcaatatgaa agaaactata actttttatt caatctttta tgtttaactg
    16261 gtttatcgcc aattttttaa aactttgatt attccttata ttataagaat agacattaag
    16321 tgaactaatt caatcatact gattctttcg tgtattcaaa attagatgct gtttaataaa
    16381 attattcttt ttgaaaaaga attataacta tatcccaaaa attgtaggtt aatttaaagc
    16441 ctatttcatc atcgtgattg agcttctttt tcatagacga atttctcaga tagtttagtt
    16501 ttctttatga gatttttgta tatttctgac cttcgataca actcattatg agtaccttga
    16561 tcaactagtt ttccttgatc catcactaca attttattta ccttttcaat agacttcaag
    16621 cgatgcgata taattagtac tgtcttatct tgtattaaac gatttaaact ttcctgaata
    16681 cgtttttcat tttccgcatc taaactggca gtaatttcat ctaaaattaa aattggcgca
    16741 tttttcaaaa aagcccgtgc tatggatagg cgttgtcgct ctcctccaga aagtgaactt
    16801 ccgttttctc cgaccaatgt atgataaccg tcaggtagtt tttcaataaa gtcttcgcag
    16861 ttagctaaac gagctgcttt tttcacttcc tcatctgacg cttgactatt tccaatacgt
    16921 atattttcca aaatacttgt attaaacaaa gttacctctt gaaaaacaat agcgattttg
    16981 ctaaacaaag aagctggaga tacacgttta atatcatacc catcaattaa aatacagcct
    17041 tcatcataat catacagtct agacactaat ttcaagatac tagttttccc ggaaccacta
    17101 gcacctacta acgcagtcac ttctccttgt ttagccgtaa aagagatatg atctaaaatt
    17161 ggggtattgt tatcatatga gaaagagaca tctcgcaact caatgtcaaa agatttcaga
    17221 ggactatctg atccctcttg gatactggtt tccttcatag ctctaattcg ctgtatttta
    17281 ggagctaaat aaaatatttc aagcactgct tctttcatag aatcgaagga atcctttatt
    17341 tttattgcgg ctagtaagta accaacgacg tagagtatag tcacttcacc cgttaacagt
    17401 aagtgaacac ctactagaat gactactgct aaactaacat atgagaaaat agaggataag
    17461 gccatgactg aaaaagtact taattctacc tttaaatgaa tcctttcact ctcttccatt
    17521 tttttgaaaa gtctgtcttg aactttttta gatagattaa agctattaat ctcttgctgc
    17581 aattctatag tttcttgaaa ttcttccgag ttttctctca aagtatcgta atatttagta
    17641 ttggctttcg tttgggattt ctttgataac aagattaaga caaaactaaa taacgttggc
    17701 aaaataacag ctaatcccat tttgacatta ccaaccaaaa gcatcactga aataaaaggg
    17761 aaaaacagag ccataccgcc ggctttaggt attgcatgac tcatcgcatg ctcaatacct
    17821 tcaacgtcag acatgatagt ttgagataaa tctgataaat tatgttttga aaaataggat
    17881 aatggtaaat ttgacaaatc gtctgcaatt tgcactctta aatgcgcact ttctttataa
    17941 gtactattat ataagttttc atactcccta tctaacaacc aatacatgaa aagcaaagta
    18001 acaaacgata cggcaaaata aagccaacgg ggctttgtat tttctaaaac taattcgtct
    18061 atcagcatca ttataatgaa tgctggtacc atattaatgc agtatacaaa aaaactagaa
    18121 atagaagctt tagttaaagc ttctgcgccc tgatcactta aagcaaattt gtttttataa
    18181 aaacttttca ttgtcaagcc tccaatcatt tgcattctca taattagtga ccaattgttt
    18241 atacacttga tgtttagcca ttaattcatt atgatttcca cgttctacta ttttcccttc
    18301 tgacaagaca agaatttcat ctacagattt aatgctggat aatcgatgag ctatcataat
    18361 aactgttttt tcttttatca gatgttgaaa agccttttgt agttcatact cattatctgg
    18421 atcaatagat gcactggctt catccataat aacaatcttt gcatctttta aaattgctct
    18481 ggcaatagct atacgttgtt tttctcctcc tgacagataa actcctttac taccaattaa
    18541 ggtatgctct ctttcgggaa atttttctaa aatcgattcg caaccggcta atcttagcgc
    18601 gtcaaatact ttacttgctg gcgcttgagg atttgctata gaaacgttat cgtaaatact
    18661 ctgattgaat agtttcgtat cttgaaagac aaaagcaatt gtgttaataa ttgtgtcttt
    18721 tgaatagtga tttaaaggct taccaccaat tttaatctgt cccttatcca cattgtagaa
    18781 acctgaaatt agtttagcta tcgtactctt tccgcttcct gattttccta ctaatgcata
    18841 aattcttttt tgttctaaaa ctaagttgaa attttctaaa acacactctt ctttgtatga
    18901 aaagctgaca ttttcaaatg caatgtcaca atttttaatc tgtgtctcgt tcccatattt
    18961 tagttggtct tgcttcattt ctaaataaag ggagtctagt gtttcgactg catatcttgc
    19021 ttcaaacaag tgcatactta catacattat tctcatgaaa gaaacaaaaa taattccact
    19081 taaaaaaaac aacatcaaca agtcaacagc taatatcttg ggagtggtaa gagaagttat
    19141 aaaaaaggtt ataggaacta tcaaaatgca aactatgcca aaaaatagcc attgaaaaag
    19201 aacaaaaggt gttttcccac tcaaagaata cttatatgca aacttagcat aatcgttaat
    19261 tgctttattc aaggctttaa atgatgttac tttagcacca aatatcttta taacttgaat
    19321 tccgcggata tattctaccg tttcagagct taacacatct aacgattctt gatatttttg
    19381 aataaaattt gtattctctg tcattttctt taacaagaat acaccaatta ctaacatggc
    19441 gattagaacc aatccaattt taaagttaat gaaaaagcct aaggcaactg ataaaacagg
    19501 tgttactatg gcttgagcac tatctggaat caagtgagca attgccatat gtgttttagc
    19561 cgcgttgtca tcaattgtct ttcgaatata tcccgaagaa tttaaatcaa aaaaacgaaa
    19621 acttgcttct gttaaaccgc taattccctt ttttctcaaa ttagtctcta agcgaaaccc
    19681 aaggatatga gaaaataagc cagaaaaaat ataaaataaa gctcctaaag ttaaccaagc
    19741 aacagtttga accgcataac tcttagctaa atattcatct cctacaataa ttagagactg
    19801 aagaaatttg taaatactgt aatatccata gactgttaat acgacagaaa aatcagaaaa
    19861 taaagtggct aaccatccgt agtatttcat tttagggaca taactaaata attttttgta
    19921 tactttcatt ttttcctccc ccgcattcaa tttcttctct tattcgttta caactgttaa
    19981 tgctttccgt aatagcgtaa attagagatg tacaaacaga taaaaggtaa actacgttct
    20041 attttttgta tttttttaag acttttcttc caatcaatac accaatcata gataaacttg
    20101 ctacaactaa cactgaaatg attccccata tacctaccgc atagtggatc attgcatcca
    20161 ttgttgcagc agattgtcct ttatctatcc aatcttgacg aaaacgatct gtaaagaacc
    20221 atataggaat ccactgtccg gcagcactgc ctaattgcat tagagcccaa gacgcaactt
    20281 gaggaattgc tcgatcatat ccaaatacag atagaataat atcagctaag atcgccatac
    20341 taatcgaact gataaaccaa ggtaagtacg ccccgcccat taacgtaaaa aataacaata
    20401 aaacaattgt gtaaatagta aaaattcctt ttctagggta gttatagcta atataaacaa
    20461 atatgattcc agataataat ccaaaaatcc cgggggatat gctgtgacca aacgccccac
    20521 caatactact aaccattatt gaaaaaaagt aaattactag ggaaataact gtagctaaac
    20581 caataaaaat ataatctttt gttttcatat atattctcct caattctatt tcgttatgtc
    20641 attaaaaatc tgttctatca aagttgaatc ttctactcta agttttatat ctttttttat
    20701 tccaccattt tttaaataaa taattctatt gcatgtttta taaagaaatt ccggatcatg
    20761 agtagctata actactgcac ccttttcttt taagtcttta ataaggtcag caatcctttc
    20821 catattaata taatccaacc cacttgtagg ttcatcaaat agaaataaat tagtttttga
    20881 caatgaagct atagaaacca ataatctttg tttttctcca ccggataaat caaacggtaa
    20941 ttgatctttc attttataaa gttccatttt ttttaaaatt ttttcttgct gatctttact
    21001 aactatttca ttccccaggg ctaactcgct cctcactgat tctgtgaaaa attggtaatc
    21061 catttcttgc attactaaaa acggcgatga caaatttttt ttattttcga ttatctttcc
    21121 tttggtaggg cgaataatct tcatgagtat tcttagtaag gttgttttcc ccacaccgtt
    21181 tttccctacc aaaccaataa catctccaac tttgacatca aaatttatgt cttttagaat
    21241 attttcataa gtaatttctt caacttttaa tacatctgca cttacctttt cgatataggg
    21301 aacttcaatc gaactattaa aaatgtcaaa tttccttaat gcgttattgt tttcagtttt
    21361 taacaactga atagttgtag tttttacagt tctattttta acaaatagaa cttgatcaat
    21421 taattctttc aaatagtaaa aacgatgttc agctataaca atagtaaatc ctttattttt
    21481 taaatcacaa agtaagtcag caagtttctt agtcgctttg aagtccaaat ttgaagacgg
    21541 ttcatccaat ataattaatt tagagtttag cgataaacta catccaatag aaattttctg
    21601 ccgttcacca cttgatagcg aaaaaatgtt tttatctaat atatttgaaa gatctaataa
    21661 ttcagctaat tcattgattc ttttatccat atgctctttt gtaaatccaa agttttccat
    21721 cgaaaatact aactcactcg ttgtatttgt tgtaaagaat tgtcctctag gatcttgact
    21781 tacgtagcca atattttttg atatactttc ttgtgttaag gattgtagcg agttattttc
    21841 aaataaaatt tccccaacca attttccgtc ataaagtctt ggaataagtc cattcattaa
    21901 ctttaatagt gtggatttcc cactcccaga agaaccagta atcaatgtaa gactgccttt
    21961 ttttattgaa aaattaaggt caacaagcgc ttgttcctta acatccttat atgaaaaaga
    22021 aacattgtta aattcaaaca attctttcac ctcaaatcaa aatacttaag aaaaaaatag
    22081 taacggaaaa caggatgata tagtctaata agctcatgtt tgttttatag taagaacttc
    22141 ttttcacagg agattctatc ccctttgtta ttgcattagc ggtcatttct tcagcaatca
    22201 tagttgcacg tataagaacg ggaactaaca gaaattccaa atattgcaga ggctgaaaaa
    22261 aagacaagcg aatgtttctc atttttaaag attctttaat cattcttatt tcagaacgat
    22321 aagtcggaaa gaatctgatc actactgtaa tacttaacat tatttttttc ggtaaatgta
    22381 ttttttctaa agaggataat aattcattgc tagtatagac actaaccaac aaccatgaga
    22441 tcattacgac cggcaacatt cgaaatacaa tatataagga tgtcgcaaaa aatatagtaa
    22501 aaaactctat cttgatagca tcaataattt tcattactaa aaacagaact gaataaatca
    22561 agatgaaata aatacatgtc tttattttac gaaacatcaa tactaaaact gtagcaataa
    22621 tgaaacaccc cacttgaaat atatttccct ttcctaaaaa aataatgacc ggaaaaaaaa
    22681 tatttaaagt aatcaaggtt aacggattga tttttgacac tctttcacct ccaaaaaata
    22741 agatcgcact gttatcttaa gctgataaaa atgcaccgtt attcagataa cagtgcgatc
    22801 ttatcaaaaa gcataactga gaacaattct caatgcaagc tttttttaat taactcagta
    22861 attcaatcca cccaggaaca gaaaattgat acaatcttct ggttaatagc atagtctttt
    22921 cttttgaata gctatgcttc aatatatcat agaatgtagc gtagaatgag taaatgtaga
    22981 agtggatttc ttcttcatta aagactaaat tttgattgat cattccgata gtctttaact
    23041 tatctagaca acagactgtc tttttcgtca caaatgatgt aattttttca acaatatctt
    23101 gatatttggt tccagctgat tggaataaaa tcaaatcgaa tatacgttta ttctcaaaaa
    23161 tataattaat aaatggatct aattcattga agttctctct ccaacttttc tctatatcta
    23221 tattttctaa gtttaagagg tatttggtaa actcttcatt atacatatta ataagcgcat
    23281 taatatgcgg ctgaataatt tcttcaaata acgcttcctt agaagtaaaa tgtttataaa
    23341 aagcacccgt agttacgcct gcggtcaggc acagttgcct tatcttagtt tgctgaaatc
    23401 cttctttttc aaaatggctt agtccacttt ctattaactt ttggtgagtt ataatataat
    23461 ctctggtttc tatgggtact tcctcctaat aagatgaatt aactttatta tcttacacag
    23521 gacttgaagt ttcaatcgtt aacgtttatt actgaactca ttccttagag ctaaactaat
    23581 gagaaagagc agaataactg atacaaaaag caatcctaca agaattaata gactcatcta
    23641 aatcattcac cttttctaaa ataatccgag aaagatttaa aaaaattata tccagctatt
    23701 aggataagtc ctatcataat cactccaata gccattttct tatcctccct aaaaataaag
    23761 tcttttactt aaaacctttt ttgtaatcgt caataaattt tttcccttta tcagttaatt
    23821 gaaatcctat atctaaatag tcctcatatc taagtttagc cagcatctca cttacagatg
    23881 ctggactaac acttagaact tttgctaaat cattattttt taatttcttt tttctttttg
    23941 ataattcctg aattgctagt aaataaatta gtatagtagt cgttttaatt tgtaccatac
    24001 ctaccctcca aattatttcg aaaggccttc agcaatttta tccaggttcc atttcatcat
    24061 cgcatagtaa ctatcaccat cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga
    24121 atagatagga atattggtat cttttgatac tgttttcatt ggtctatcat ccacactgct
    24181 ttctacgaat aaggagggaa cttttgttgt gcgtaatttt tcaactaagt gttttatttg
    24241 atctggtgtt ccttcttctt cagtgttgat ttcccaaatg taagcagaag gcacattata
    24301 cgctttcgag aaatatttaa agcatccttc acttgtaaca atcatttttt tatcattcgg
    24361 aattgaagca aatttagatt tagcttcttt gtctagagaa tccaattttt caatatactt
    24421 atctagattt tctttataga attttttatt atcaggatct ttttccgcta actgtttttc
    24481 aatattttta gcgtaaataa taccgttttc taaatttaac caagcatgag gatcttcctt
    24541 ccctttctca ctctgaccct ctaagtaaat aacatctatg ccatcacttg ctgcaaaata
    24601 gtctttgttt tcctctttgt tcgcattttt aactaatttt gtaaaccaag catttcctcc
    24661 agtttccaag ttaacaccgt tataaaaaat caaatctgct tttgaagttt tttgaacatc
    24721 ttcaggcaaa ggttcatatt cgtggggatc tttcccaata ggtacgatac tgtgtaaatc
    24781 aattttatct tttgctatat tttcggtaat atctgctaaa atcgaattag taactactac
    24841 ttttaatttt tcgttcgaag ccactttatc tttgtcttta ctatttattg aacatgcccc
    24901 gaatataaaa agagcaatca aaatccccag acttcccagt actgctttcc attttctcat
    24961 cataacgatc tctccttctt tcttaaaaat ttttgttttg gtgagattag aaaactaatt
    25021 acaaataaga atgccgctgt taaaacaata cttgatcctg ctgctatgtt aaaactataa
    25081 ccaataaaca atccaagcaa tgatgaactt gctccgactg ttgcagaaat aaatatcata
    25141 gttttcaagc tatttgcata taaatatgct gtagctgctg gtgtaattaa cattgcaaca
    25201 attaatatag ttcccacact ttgcatagct gttactgcta ctaaagttaa tagaaccatc
    25261 aatagataat gataaaaact gacattcatc cctattgctt ttgccattaa tggatcaaaa
    25321 gaagtgatta ataattcttt aaaaaataga actactataa ccaacactaa aaccgaaacg
    25381 ccaattgtaa tccacttatc aatatcttgt acagctaaaa tatttccaaa taaaatatga
    25441 aataaatccg ttgagctatt tgcaactcct ataaggataa ctcctagtgc taaaaaagaa
    25501 ctgaaagtaa taccaattgc tgtatctcct tttattacac tattgctttt tataaaagta
    25561 ataatgatag aagctaatag accaaataca atcgcaccaa taaaaaaatt aatacctaaa
    25621 atataagaaa ttgctactcc tggcaaaaca gcatgagaaa tagcatcacc cataagagac
    25681 attcctctta aaataataaa acaacctact gttccagaaa caatccctat aactacagat
    25741 gtaattagag cattctgtaa aaagtgaaag tcatacagac cattaataaa attttgaagc
    25801 atattattcc ccctctccaa taaatatagt atctccatag gcttttttta aattttcttc
    25861 attaaataca gattctacac ttccgtgagc aattagattt cgattcaaaa gaataatatt
    25921 atcaaaatac ttctttacct tgcttaaatc atgatgcaca attagcactg tttttccctg
    25981 atgtttcaat ttttttaacg tatccataat tattcgttca ctaactaagt ctatccctac
    26041 aaatggttca tctaaaaata tgaaatccgc attttgagca agacatcttg ctaaaagtac
    26101 acgttgaaat tgtcctccag ataattctcc tatttgatga ttagaatatt ttcccatatc
    26161 gaccttttcc aaagcctttg aaactctttg ccattctgca tttttaattc tttgaaaaac
    26221 tttcattccg gcatatgttc ccatagatac acattctttt acttttattg gaaaagtaaa
    26281 atcaatatca gctttttgct ctacatatgc aatcttcacc agttttttat tgatatcttc
    26341 attattaatg gagacctctc cctgatgagg gataatattt aacattgctt taagcaatgt
    26401 ggattttcca gcaccatttg gaccaataat acctgttaaa gcaccttctt gtatttttaa
    26461 agaaatctcg ttcaatgcta aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa
    26521 cataactttc tccttctaaa tgataatgat tatcacgatc atatggtata caaaaattat
    26581 attttagtca accctaaatt ttatagttta gatttttttc tgttgctgaa gattagaatg
    26641 acaaaactat ttgaaactac gcgtatagta agtagctttc aaaatatata aaaaaggagc
    26701 gttctcaaat gagaacatgc tcctaaaact actttattgg cgtatggaaa aattatactt
    26761 gaagtggata gcgggttgaa taagttgata agcatcaaaa catttataaa aattattcaa
    26821 gactatgtct gttccatata caaatatgaa aatcagtaaa ctccatttaa cttttttcgt
    26881 agtgtgtctt tttatacatg tttatcgtta ttaatagtga ataggaaaaa aactattttt
    26941 gatcattgac aattaaatac aatttttgaa taacgatccc tgctattcga gctagaaact
    27001 caagtacgcc atgacctgat tagcgacaaa tacttagaga tttctttttg ttctgggaaa
    27061 acaaaatgcc atgacaatag cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg
    27121 gggagaggtg aaattcctat gtgcttaccc aaagcaattc aaaaatttca taactactat
    27181 tttaggagat gattttatag aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt
    27241 tctaggaatc gataataata ctctagataa gtggattcgt atatataatt tcccagtaat
    27301 aagagttggt ggtgtagttc gctttgacgt agaagatatt aaagacttta tgaatacatt
    27361 taaaataact tgaaattttc ttctcgccgc atatactaaa attagtgaaa tatactgcct
    27421 tacttttttt aaggagtgag gattttgcct acaaagcttt caaatgggaa atataaaact
    27481 aatctgagat atccaaaaag gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa
    27541 aaaacatttc caaataggca attggcgatt aaagccgaaa atgatatgaa gaagaaaata
    27601 gaaaaagttt tgagagagga gaatgcaaac tcattagaat taaaaggaaa aataacgttt
    27661 aaaaaatttt acgaatctaa atggcttcct agatatgaat taggtcaaac aattagatca
    27721 aacaggcctc ctagtgatat aaccattagt aatacaaaag atatatttcg gttgcatatt
    27781 ttacctatgt ttggtgaata cgcaatgaat tatctaaata tcaatactga gataatatca
    27841 gatgaattaa ccaaaaaatc gaaagaatat gcaaatataa aaatcataaa aggatatgtt
    27901 cgttccatgt tcgatattgc agaaatacta aattatatcg aatttaatcg aactactaaa
    27961 attattcaaa gtatcactgc acctaaaaaa aatgctttag aagaaaaaag aatacaagaa
    28021 ggtaagcaag cactatcatc aaaagaactt actaattgga tagaagcagt aaatgatgat
    28081 tttaataatc atttacttac ttttcatgat tacacacttt ttatgattac cctgtatctt
    28141 ggtgatagaa aaagtgagac ttacgctttg caatggaaat atattgattt tgaaaaacaa
    28201 acggtccgtc ttaaacatac tttagataaa tatcaaagaa aaaagtttac aaaaggtcga
    28261 aaagataccg tcattcaagt accagaagtt gtaatgacat tgctaagtga atggaaatcg
    28321 gtacaagctg atcaattgtt gaaattaaaa attaagcaaa cgttagatca gtatctcttt
    28381 acttatacta aaccatctgg agaagtaaat tgtcctgttc atgccgatta cctaaactat
    28441 cgaatcaatt caattaaaag aaggcatcct gacttagttc atttatctcc acacaaactc
    28501 cgtcatactt atgcaactat agctagacaa ggtggagcag atatgaatca aatttcaaat
    28561 gctttaacac actcagatat ttctacaaca aagatatatg tgaacacacc agatatagtt
    28621 gataaggctg tttttgaagc ttttcagaga ggattgaata agtgtgattg atatgtgttc
    28681 ttaaatgtgt tcttaaaaac aaaagaagca ctttccaaat aattgaaaag tgccagaaac
    28741 gttgatatat aaaggatatt aacgttttga gaattgtgaa gctttacgtg ctttcttaag
    28801 acctggtttt ttacgttcga ccatacgtgc gtcacgagta agtaagccag cacgtttaag
    28861 agctaaacgg aagtcaggat caacttctag caatgcacga gcgataccat gacggatagc
    28921 tcctgattgt ccagcgtatc ctccgccgtt tacgttaaca aatacgtcat atgcgccttt
    28981 tgtttcagta acagcgaaag gttgattgat tacttcacgc aagtcagcat gtggaatgta
    29041 ttcttcaaca tcttttttat ttacagtaat tttgccagtt cctggtacta gacgtacgcg
    29101 agcaactgcg tttttacgac ggcctgtgcc gatatattga acttgtgcca atgaaattcc
    29161 ctcctattag attaagtttg tgatgtctaa aacttctggt tgttgtgctg catgtggatg
    29221 ttctgctcca ccgtatacgt tcaattttgt aaattgtttg cggcctaaag tgtttttagg
    29281 aagcatacct tttacagaag tttcgatcaa acgacgagaa tttttagcac gcaattcgcc
    29341 agcagtgatt gatttcaatc ctcctgggta gttgctgtga cggtaataaa ttttgtcagt
    29401 cgctttttta cctgttaatt tcactttgtc tgcattgatg acgatgacga aatcgccagt
    29461 atccaaatga ggtgtgaaag ttggtttatt tttaccacgt agtacagatg caacaactgt
    29521 tgaaagacgt cccaatggaa catcagttgc gtctactaca taccatttac gttctacttc
    29581 gcctggtttg gccatatatg ttgtacgcac gttattttcc tccaatttaa gttctgatgt
    29641 ttgacataca cttcgagttt ccggggctct ttgtggggca aacaatacca tttaacatat
    29701 tacccgctaa tctagtcaat gtcaacgttt ttctgcttga ttgaaaaatt tatatgaaac
    29761 tttacttctt ttctttcttt tatataaaag ggtcgtttcc tgtcaaaatg aaaaacaaaa
    29821 agaggctgtg acaaaagtct tgtcacaacc ccttattttg aataaacggt gttctcctgc
    29881 caactcctcg gtcacaagtc acaatatcca taaaacataa gaagctgttt tttaaaattg
    29941 tttcttgtga ctcggagctg aacggcaggc ttacaacctc ttggtaaacg gtgttcaatc
    30001 agctgaccct cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgacgtttg
    30061 tttctctaat actcaggtca aaacgctgat ttcacaacct ctttttcggt caagttcaac
    30121 aacagttttt acgcgtcgat ctctggcgct ttgcccaaat gagcttggat catccagata
    30181 cgtttttctg tggctgtttt gaattcgata aagatatctt gtgttggatc gtcgccttct
    30241 tctccagaaa cttcgattcc tttttggtaa agatctgcta gataacgata gcctgcaaca
    30301 agtgtttcca aacgttctgg aatagtacga tcccagcggc caatttcatc agggattttt
    30361 gtgttatctg caaattcacg caatgtagaa taaggtgaac cgtctaatgt gatcaagcgt
    30421 tcggatactt catctaactg agcgttcaaa tcatccatga actcatccat cattgggtgc
    30481 aatgtaagga aacctggtcc tctcatgtac caatgtgttt ggtgaacaac aacagacatt
    30541 tggcttagat ctgcaactaa ttgatttaat acttctttgg tttgttggaa tttcatcttt
    30601 cttgcctcct aacattttct tacacttaaa ataatagtag actttcaatg aaaagtacaa
    30661 caaaatcatt tacctgagaa cgattttcag ttcgcttttt tatccgtaaa gccaatcatt
    30721 tttcagaatc agctaattct tctcgcagtt gagcaaattg ctgataagtc tgtgctaaat
    30781 gcttttgtgt cgaaacaaat aatggataga ttttctgata ttttttatga tcagtttctt
    30841 gtactccaac ttgctctttc aattctatca attcctgtgc ttcactgata ctttggatct
    30901 ttccgatgct tctccagcct aaaatcacag ctcctaatgc ggatgcttct gtgacagtag
    30961 ggaaaacaag cgggtaaccc agtacatcag ccatcatctg acgaaaaatc ggagattgag
    31021 caaacccgcc tgtagcacgg atctctgtga gctgattttc ctggcaaact ccttttaaaa
    31081 tccgataaag gttgagacag atcccttcta gaatcgcctt catcatttct ttttctgtat
    31141 gttgccgctg taaaccgata aaactgccaa acgcatctgc gtcccaaagc ggtgctcgct
    31201 caccaagtaa atagggatga aaaatcagac cattggcacc cgctggcaca aaagcgatag
    31261 ccgaaagcag tgcatcatat ggattttctc ctttttcttt agcagattga acgacttcct
    31321 gtaaaaatgt atgccctgcc caatcaaaga tgccagcacc attgctagtc gctcctccca
    31381 ctacccaatg tttctgatcc agaacataac aaaacgtctc catttctgga tggaactgag
    31441 gctgagtagt aataaaacga agtgctccgc tcgttcctac ggtcaaagcg gcgatcgtat
    31501 caccaaaagc acctaaccct agattagaaa gcggcccgtc tgcccctccc aaaacaaatg
    31561 atatatcatt tggcaaacct agttctgctg ctgtttttga tggtagacct gttacttgat
    31621 aggtggaagg aaagacttgc ggcaattgct ctattcgaat gttcaagtag tcaagcactt
    31681 cttctgccca ttggaattca tggatatcaa aatatccagt tcctgaagct gttccgtagt
    31741 cgctgatcag ttcgccaaac aatctataaa agatatagtc tttgataccg acaaaataag
    31801 cagttttttt gaataattca ggttggctgt tttgcagcca cttgattttg ttcaatggtg
    31861 tcattggatg aatcggcgtc ccagtctgcc gataaaattc tttgccaagc acggtatatt
    31921 tcagtttttc tgcttcgtcc gctgctcggt tatctgccca agtgatcatt cgagataacg
    31981 gtgttttctc ttcatccaac aatatcaggc catgcatcgc agaggagaag gagacaaatt
    32041 gaatgattgt gtctgaaggc aactgtttaa ttacttcttt tataacggtg cagacacctt
    32101 gaaagatcaa ttcctgatct tgttctgcca tcccttgtgt ttcttggatc aaagggtagc
    32161 gaaaataagc ggatgctgct tcttgggctt catctgtgaa agcaactgct ttggtttgtg
    32221 tggttccgat atctaatccg attgaaacgt tcattttttc acctcaaatt ttatgtatgt
    32281 acaaaaattt agtttaagct tgcgtatctt ggttttgaaa agggggagat ggcgtgttac
    32341 tttattttat cattggttgc tgtatcggat catttttatg tttaaccgcc cagcggattc
    32401 cgttaggtca ctctattatt tatcctagat ctcattgtgt caaatgctgt cgttcgcttt
    32461 cttggtatga attgattccg attctctcga tcatcgtcca acgatttcgc tgccgctatt
    32521 gcaggtgtcg gttgcccttc tactatttgt tggcagaagc cttatgtggt ggtctttttg
    32581 cctggttctt tactttttct tccgcaagaa atttttcgac gttcatatgg atgctttcgg
    32641 ctttgctatt ttcgttgatg gatttatttt acttcatggt ccattctcac acgctattct
    32701 gttcttgggc aattttatgg attttttggt tgcaggccgg cgtcttccaa tggcaaagtg
    32761 tgctgttaac gtttatcgta ggcggtgtgt gccttcgcta tggtcaatcc tatctcggag
    32821 ctggcgatac tctgttgatg ctttcttgga gtggtggctt gtctctagaa gagttgcttc
    32881 agatcttgtt tcttgctagt ctgtttggaa tatccgtttt ttctgtttac tttatctgtc
    32941 ataaaaaaaa gttggaaaag ctgcctttca ttcctttttt gagcagtgcg ttgctgattg
    33001 tccttcatct taggtattga aaaaaggttg tgacaaacga cttgtcacaa cctctgatat
    33061 atagtgttct cttaccaaat ccttgtgact tggagctagg cgacaggttc acaacctctc
    33121 cactaaatgg tgttcaatca gctgaccctc agtattagct caaaatgctg gttttacaac
    33181 ctctgatata cggtgttcca taagtagctt tttcggcttc ttatttcttg acgccccaat
    33241 gtcgacgaag gaaacctgca cgtccagaac cttctcgata aagattgtaa tggagcttgt
    33301 ttttcttgta ataatcctga tggtaatctt ctgcaggata aaattcgctt cttggttcga
    33361 tttttgtcac gattggctta tcgaatcgcc cgctgtcttg caatgcttgt tttgaacgct
    33421 ctgcaatatt tcgttcttct tcatcattat agtagatcac tggacgataa gaatcaccgc
    33481 gatcagcgaa ctgtcctaat gcgtcagtcg gatcggtttg ctgccaatag atttccacca
    33541 actgatcata agaaataact tctggatcat attcgatctc tactgcttct gtatgccctg
    33601 ttgtgcctgt tgttacttgt tcataagttg gatttggtac atgcccgcca gtataaccgg
    33661 atgtcacaga aatgatccct ggctgctctt caaatggttt gaccatacac caaaagcatc
    33721 cgcctgcgaa aactgctttt tttgtcatat aaaatccccc ttttttctca tcataccttg
    33781 atttccaaaa ggaggataac gttttgcttg tgacagaaaa aacggaaact attatatacg
    33841 tgatacggct tctgataaat gccaaaacga acgtacttga tcaaaaacgg ttaaatcagg
    33901 aatcacatat tcagcagaag gaagatttat gttttcacct attcccaata catgcatgtt
    33961 accagccaaa gctgcttgac aaccagcttc tgaatcttca atgaccaagc atgcatttgg
    34021 cggtacattc aattgctgtg ctcctttgag aaaaacttct ggatcaggtt ttgcttttga
    34081 tacttgcgtg ccgtcaataa ggacatcaaa ataacttgtc aaattcgttt tttctaaaat
    34141 gaggcgtgca tttttgcttg ctgatcccaa tccgatcttg atgtttgttt ttttcaagta
    34201 ctcaagaaca gctattgcac caggcaaaac ggatgtttca tccatttttt gaatcgcttg
    34261 aagatataga ttgttttttt gctcagcaaa ggctgatttc tctttttctg agaatttctg
    34321 ttccattttt ccaaatgaca gcaatcgctc tagtgactcg gttctggata ttcctttcag
    34381 ttgctcgttt tctttctcag tgaatggaat ggacagctgg ttagctaaaa ccagccacgc
    34441 ttcgtaatga taacgagctg tgtctacaag aacgccatct aaatcgaata gtgctgcttt
    34501 gattttcatc gattacctcc ttgaaaatga acgacttgaa gtaaagatgc gatgttttta
    34561 gctgtgcgat gaagattatc agtggcttgc tgtaaagctt cttgtaaagg cacagctgca
    34621 ggaaggatcg gaaaaacggc cgaaatgcca acatctgctg ctttttcgct tcctttacca
    34681 acacttccgc aaatagctat cacaggaacg ccctctggta ctcttctagc aatcccaact
    34741 ggcgcttttc cttttagact ttgtccatct agacgtcctt cgcctacgat tacgaggtct
    34801 gcttgctgta cccgtttatc gaactccagt aaatccaata cgtagtcgat gccagagact
    34861 attttccctg aagcaaatgc taacagtcct gcacccattc caccaccagc actactgccc
    34921 gatgcctcga ttacttgagg ggcaaatctc atataaaaat catgcatggc ttggtcagcc
    34981 actgctaatt cattttcttt caagcctttt tgtggtccga aaacaaaaga agcgccttct
    35041 tttccgcata aaagattagt aacatcagta atgacagtga ttttggcttt aatcagctca
    35101 ataggcacgt tcgttttatc aactgtagca attttaccta gattttctcc cagtgcttct
    35161 actttttgat tatcttgatc gtaaaaagca taacctagac cttctgccat gccgatgccg
    35221 ccatcgttgg tactacttcc gccaacgccg atgatgatgt gtcgaacacc ttgttgcaac
    35281 aattgtcgta tcagttctcc tactcctcgc gtggataacc taagtggctg ttgttggttt
    35341 agtgggacat ctttcaatcc gacgatttct gccatttcaa aaatcgcagt ttgaccgtct
    35401 gaagcgtact ggatttcttt gtttttgcca aatgcattag taacgactgc tgtttgccgc
    35461 ttcaacctta aactgtctgc taatgatgaa accgttcctt ctcctccatc gcctataggt
    35521 agcagatcat attcagcctg aacaaaaact tcttgaaaac ctgattgaat ggcttgtgct
    35581 gcctctaagg ctgtcagact ttctttgaaa gaatctggcg caatcagaat acgcattatt
    35641 ttcccctccg ttccaagatc agttcttttt ccagctggta ttggtctcca ttgacaaaaa
    35701 taggtaatgt ttctttcgtc tcttttttta ttactatttg tttttttgtc aaaacaaata
    35761 gcaacctgtg atttttccaa ataaaaggaa aagaaatttt ttcccatgct gaaggaagtc
    35821 ttggagaaat agaaagagtt ccattcgtta ctgtaatacc tgaaaaacca aatataactg
    35881 ctagccatag tgctcctaat gaagcagcat gaattccgtc atctgatgaa tgcggatctg
    35941 gtcctaaatc aatcaggcac gcttcttgga ataaatgata cgcccattcc atttcttgga
    36001 tacggcaagc ctctatggcg tgaatcgctt tactcaacga tgagtcgtgg attgttttgt
    36061 tttcatagta atgcaaattc ttagaaacga ttggttgaga aaaatactca ggtaataagt
    36121 ataacagcat gacaagatct gcttgcttgc tgacttggag ttcatttact tcgctacggg
    36181 cataatcaag taaaatagac tggctgccag gacgttcttt gtaagtggtc aaatcaataa
    36241 ctggcttact gagatacgtg tcatcttgcg gaatcagctg ttctttgtta ggcactggca
    36301 aatataactt atctaaaaaa ttttgacatt ctttcaaaaa aagcggatcg ccagcttgat
    36361 atttaacagc taaggccaca ttataatgcg ccagatagtt cgtatatgca ttattgtcga
    36421 tatattctgt gtattcatct ggaccaatga ctctgtgtat ctctaaatga tcatcgactt
    36481 ttacagctct gctcagccaa aaagctgctg tttcatgaat gagcgttttt ccctttgttt
    36541 ctaaaaacga ttgatcctct gttgcttgga catactcttg aacggcataa gcaaggtctg
    36601 cactgatatg atgttctgcg gcagctgaag caacttcttg tcttgttccg gttttgatat
    36661 tcaatgcagc aaatttgggt gtctcttcct gaccagtgtg tgcgctttcc catgggaaaa
    36721 gtgcaccttg atagtgataa tctcttgctt tttgccgtgc gccttctaat cgatcataac
    36781 ggtacagcag caaattcttt gctacttcag gaaactgata taaaaagaaa ggcaggataa
    36841 aaatttccgt atcccagaaa acatgccctt tataaccttc gccagttagt cccttcgccc
    36901 ctacactaac acttggatca ttgcggggag tcataatctg taaatggtaa gcagcgaagt
    36961 ccatcgctaa ctgatcgaaa gaagaatcgc cttggatcgt tatccgatgc tgatgccaaa
    37021 aatctgtcca ataagacatc gactgctcta aaatttctgt ataactaacg cttttctggg
    37081 cttgggcaat acctttctta aacgggtctg tttgctgaag agaggtagag agcacgatga
    37141 tcttctccag cgtaaaggac gtattttttc tgatcttttc tgaaaaggaa gcggtgatcc
    37201 ggcgattttt tgcttggaat acacctgctt tattgaattt agctgcaatc ccaatatcaa
    37261 ttttactttc tgttgtctgg taggatgcac tgatcaaatc gtcaccaaat actcgcagtt
    37321 ctttttcaac caactgctgt gtaccaaaat tggtttgctg tccatcgata cccgttttca
    37381 catctacttg gcagtcttcg gtcaacggct tgatgaccac tttcagggct gcctgatgga
    37441 gattattttg atcagcaaca cgacaagtaa tgacttccac tttttttcct tgagcagttt
    37501 caatgagcgc atagcgttta agctctccca tttctaaatc tagtgcccgc tcgtatgcaa
    37561 gaactttcat cgtctcaaga gaaaaatgtt caccgtcgat ttttatttcc catctgatga
    37621 catctgggag attcactaac tcggctgatt ctgctcctaa aggtcggtta tatacaccag
    37681 ctgcaaacat tccccttact tgattccgat agtcttcctc ctggcttcct ctgataccaa
    37741 aaaatccatt tccaatggtc atctgactcg catacttatt gatatactct aaatcaaact
    37801 gtttttcttc tactttcata aggtaataac ttctcctgtt tctgccgaac gatataaatt
    37861 ttccaccaga ttctggatga catatccttg ccagccatct gcaatcatct gagtctggtc
    37921 accgagcgcc cgattcacaa aatgagccat acttagttca tgtgggtcat taactggcgt
    37981 ggtcttttgt aaggaaacca gctttccatc tacatcttcg aatagttcgc ctggatacag
    38041 attagcacct gcctgatcgc cacaaaaagc cacattcagt ttgtcttctc tgatattcaa
    38101 agcaaacgaa gtattcagtt ggatgatctt gccgttttct aattccagtg tgccaaaaat
    38161 tgcatcttct actgtgaatt tgcttggatc ccatttcccg aatttccctg aatttttttt
    38221 cgtaccaatt ttttggaagc tgtacgcccg aacgcttttt actttaggaa atccagtaat
    38281 atacatcgct gtatcaagca tgtgaatgcc ataatcgatc aaaggcccgc ctccttgaag
    38341 ttctttgtcg ataaacgttc cccagcctgg aacaccagac cgacgaagcg cattcgcttc
    38401 tacgtaataa atatccccga gaacatcaag atgattcttg atcattgttg cttcgtcaga
    38461 aaaacgatgc tggaatccat aagccaaaat ctgcccgttt ttatcggctg tctctgccat
    38521 ctttcttgct tgatcagctg tcatagctgg tggtttctcg cacatcactg aagcattagc
    38581 ttcgagggca gccaatacat gttcgaagtg aaagcgattg ggtgtacaga cactcacgat
    38641 atcgggagaa atctcattca gcatttgtgt aactgatgta tacgcatgag aaaatcctgt
    38701 acgtcggcaa aagtcttctg ctcgctggct gactggatca accacagcgg ccaattctaa
    38761 gacatctgat cttttttgat aataagcagc atgtactttt tctgctactt gtccagcgcc
    38821 tatgattgct actttcttca tttatttctc cctcctttgc ttatttactt attgttattc
    38881 tttctctatt ctttctctaa atcatttaaa tgacgcgctg tttccagaca gtttttcaag
    38941 tattgcaatg attcctgata aattttcact tcattttctc ctcgcaaacg acattcatat
    39001 accatataac cttcatactc attttgaagt agcgtttgaa aatggcgagt aaaatcaatt
    39061 gcgccagatc ctggttggta gcgatgatta tctgctaaat ggatatgacc cacatactct
    39121 ttttgcgtag tcaatgcttt tgaaatatca tcttcttcaa tattcatatg ataaaaatca
    39181 gcgatgatct gcacatgttt caattgatta gagtcaatgt aatgacgcgc atccgctaac
    39241 aaattgatca tatggtcttg gtatcggttc aaaggctcca aataaataac cgtacctgtt
    39301 tcttcggcta ctttatctaa ataacgaagt gattcgctga ctgctttata gtctccttct
    39361 ttgcttcggg gtgaaaccat cggcggtaat cgataagtga acattcccca agctgctggg
    39421 ataacgattc ctttgcctcc aacctcgctt agtgcacgca aaatctcagc aatttgacgt
    39481 acaccattaa gacgccgttc ttcgataaag tcaccgatcc acccatcgta gccgttacaa
    39541 gctgtcacta ctgggatccc tgtttctttg attgcctgtt tgactgtgtc gatattttct
    39601 attaacaact taccgtcgat ttcgtattct tcaaatccac agtctttgat aaatctaaat
    39661 ttttctaaaa tgtctcttgg gaaaaatgct tgatcttgcg taccgaattt cattgttctc
    39721 ctcctcggac ttgaacgccc attttgatac tttcttctgg gtgctggtct acataacgca
    39781 tgtaagcttc tgcgctttct gcaaatggca caactggatc aatgatttct tcacaatcca
    39841 agtaaccgtt catcaataat tcccaacatg tgtcctcgat tcgtttacgg ttccatcttg
    39901 ggtaatctgg gtttggttca ctagatgctc gagcaaagac gatttttgca ttattgaaat
    39961 gtgcttcgcg accaagatta aacccagctg gaaaaggttt agcaaaggca acataagaaa
    40021 tgatcccgcc atagccgatc cctcttaaag aagcttgtaa tgcggcagca ctgccactcg
    40081 tttcaataac tgaatctact ccacgtttat ctgtcaattc ctttagacga aaaccgacat
    40141 ctgctttcat aggatctagc gtgtaatcgg caccgtattt ttctgctaat tctctacgct
    40201 gcgctatggg atcgatccca acgatggtag tagcacctgc ttttttagct aattgaatcg
    40261 caatttgccc gatagcgcct aaaccgaaga ttgctacagc atcacctgct cgaacatgtg
    40321 cttcccggat accacctaaa gcgaattgag caggatcgta acatactgca tttttccatt
    40381 gatccaaccg atcaagttta cgtagtttat aattatcaac accgtttgta atcagcgttt
    40441 cacgaatggg tccataagtg cagactaact ctcctttttg atactctgtc accaaactgc
    40501 ccgtttcttc gatcgtaccg acaatcatat ttcctaattg aaattcgcca aataccacac
    40561 cgcgttggct tccttcttct cttggcaaga ataggcgcca ttcttctgaa aattcttcat
    40621 cgataaatgg acttaatcct ctaaagtcga caatttctgt tcctggtttt ggagtagcga
    40681 aaattactcg gatacgtact tcgttctttt cgatctcacg gtcttcgtaa tctttgaatc
    40741 cggctattct tggttctaat gcaactaatt ttttcatctt ttctttcctc tttcttttct
    40801 ttttatcctt ttacgccgcc ttcgactaaa tcacctttaa taaatcgttc agataacgca
    40861 tacataatga tgactggtaa agcggtcacc aatgaagcgg ccatcattcg tccccaaatg
    40921 tagtctggtg tactgaataa tgtgttcaaa ccgattggta aagtaaattt ttcggaggtc
    40981 gacaggaaaa tcgaagcaaa taaataatca ttccacgaaa ccataaagca ataaacgaag
    41041 acagaaatga ttccagaaat agccaatggt ataatgatcc gaataatgat ctggatccgg
    41101 ctaagaccat cgatcattgc tgcttcttca atatcagtcg gaatcgtgtc aaaataactt
    41161 tttagcatga atatcgcagt aggaagtgtt tgaacgacca tcgtgataat cagtgctgta
    41221 ttggtatcat acaaacctag accggaaatg attttaaata atggaacaac gatcaaaata
    41281 ccggaaaaca tataaacggt gtaaaagcta gcattgattt tcgagcgagc tttgaagcgt
    41341 agttttgaca aagcgtatgc cccgctgatc ccaatcacta ctgcagttac ggaggctatc
    41401 aaggagatca ctaaactatt tttgaaatac atgatgaatg gaaaaatctc agcattgaaa
    41461 atatcctgat aatgttcaaa agtccattct ttcggaaaaa tagtttgtgt cgttgcaatt
    41521 gcttcttgtg aatccttgaa tgatgtcatc agcatgatca aaaatggaaa caaattgaca
    41581 gctaatagca acaaaatcgt cgcgtaaaat aagattttcc tgctcttttt atttttcatt
    41641 tcaagtccac cttctttcgt gagagcaaga cgaccgctgc aataatgatg aacaatagaa
    41701 tcgatatagc tgctgctttt ccaagatcat tgaacgcaaa ggctgtctga tacaaataaa
    41761 cgcctaagat attgacttta ttcgtcagta gatagacatc tgtaaacata tagaacatcc
    41821 agatagatcg taaaacaatc acagttgcta gtactggttt gattgccggc agtgtcacga
    41881 tcttgaactt ctgccaagca tttgcaccgt ccatttcagc tgcttcataa agcgttttgt
    41941 cgactgtttg caaaatagcc aaaaatgaaa taaacgcata cggatagtat ctccagatag
    42001 caaacaaaac gaccataaag aagctagcaa ctggctggtc gaaccacagc ggtgcttcgt
    42061 tgaaaagctg caacctatct actaacagat cattgacgat tccataacta ttattgaaca
    42121 tatatttcca agcaaaaatc aaagaaatag atggcgtaac ataacttaat aaaatcagtg
    42181 aacgcaccgt tttcctaaat ctgaacttgc ggttaagcaa aatagctacg gctaatccta
    42241 aagctgtact gcctgctaca actaagaatg tgtaagcaac tgttaaacct aaagaacgat
    42301 aaaattcact atcacttaaa atttcaagat aattgcttaa tccgataaaa acggcgtctg
    42361 agttaggatt cagcggcata tcgaaaaaac tgatctgaat attggaaagc attggaatca
    42421 gcactaaaac agctaataaa agcatgcttg gtgctaaaag tcccatggct aattttaagt
    42481 cagaatgttt ccttggacga ttcattgaaa cctccccctg ataatctgcc aatagctatc
    42541 tacttttttc gaacaccatt ggcagaactt cttgttattt cgtatttttt tgtgcgtcag
    42601 ctaaagcttg atcgacatct tcgtttccga cagttacttg gttcactgct tttccgatca
    42661 cacctgagct tgtgatatct cccattttcg tgaaattctt ttccccgact agtccaaaga
    42721 cttgtacttc atcaaaagca ctagcaatct cagatggcag ctcgccaaaa gacttgatga
    42781 cttcattttc tttgtaacca tccagttcga ctacttgttt attcactggt tgagcaccac
    42841 caggagacat caagacccac ttttccatgt ttttcggttg agataagaaa gctgtgaatg
    42901 cttcagcagc ctctttttgt ttctcgtcta gaccagaaga aatcgtcaat ccagatactg
    42961 tgccatagac agcttgatct ttttgtgttg ggatagcaaa accgatattt tctgagttcc
    43021 ccgcttcata aacagaaggc aaaatgtaag ttgaatagat tgccattggt gctgttccat
    43081 tcatgaaagc atctttgatt tctgtcacat cattagagcc tggcatcgtg tattgggata
    43141 agttttgata aaacgacaat gcttctctca tcttttccgt atcgatcgtt acctcgcctt
    43201 catcatccaa aacatttgct ccatttgaca aagcaaattg agagaacgct tgctcactca
    43261 ttgttccttc agcagtaggc atagcaattc catattgttt attctcttta tctgtgaaat
    43321 gttgagcaat ttttaaaata tcatcccaat tttctggttc tgaaaaacca gcttctgata
    43381 atttttcttt gtcataccaa ataccttgaa cccagccgct aattggtgca gcaatatagc
    43441 tttttccatc ttctgaacga acaaggtttt tggctccgtc ataataatta tcttctccag
    43501 cttcctcgat aacgttttgg actgccgtct gatcaatcag ttcatcttta tccatcactt
    43561 tagcaaaatc ctgactgact tccattactt ctggtaattt accggaacga gctaacgtaa
    43621 cgatttttgt attgaacgct gattcttcta ccggcacttg cttgattttg atgtctggat
    43681 tttctttttc aaaatcagca accagttcat tgatcacact taatcgttcc tgttcgacag
    43741 aagagtgcat gaattgaatc gttgtctgtt gtgattcgtt agagctttga ctttcaccac
    43801 aagcagtaag aagaaatcca gtagctagca gacaggtagt aacaataatt tttttcattt
    43861 ttttccacct cttattttat tattttcagc cacatatatt catacggctg gaatatcaac
    43921 tttcgttctt gactgcaatg gataatttgt ccagaaaaca ggtctaggta atctcctttt
    43981 ggtaaaagat aacctgctga ttgattggaa aaattatgga taactaagac tttctcttcc
    44041 ttcgcttcgc gaataaaact gataaaagaa tctgctgagt ccagtaagta aatcaaacta
    44101 ttcggatgga aggctttttc tttttttcga atagatagca tctgggtcaa ttcaccatat
    44161 actgctgttc ttaatggatc tgtctgcaac tctttctcaa tatctgctaa caaaaatttt
    44221 tgccgattga tttttcgatt ctctcctgtt ttttctacgc ctttgtaatc atttcgactt
    44281 cccagcacac tttgaatata aattgccggc acgcctggta acgttaccaa aaatgaatga
    44341 gcagctaaaa agcgtttgct tctccattcc gtcgtatctg ttggagaact taacgcatct
    44401 agatacgtag cgtttatctc atatggactg gtcgttccat ctgggttttt cttgtagttt
    44461 actcgggtac cctctttctt cagctgttcc actaattcaa ggatcgtttt ttccggcaga
    44521 atacctcgta ccggattcaa tccgataccg tcatgggagg ctaaaaaatt aaaaaaagtt
    44581 gtttttttcg atgcgaaatc gatggttttt aaccattctt tcaacttact tgtattaccc
    44641 gaacgaatcg cttgaagggt caaaggtggt agcgaaaact gatagaccat ctgtgcttca
    44701 ttctcgccat tcccaaaata actgatatta tctttgtgtg gcacatttgt ctcagtgatc
    44761 aataccgttc ctggagctgc ttcatcagcg attgcacgga ataattggat gattttatgc
    44821 gtttctggca ggtgtataca agaagttcct agttctttcc ataaaaatcc cacagcgtcc
    44881 aagcgaataa atgaagcgcc tttttctaag taaaacaaaa gaatatcgat cattttcaat
    44941 aaaacttctg gatttttaaa attcaagtct acttgatctt cgctaaaagt cgtccatacg
    45001 tgtttttctt tcccgttttt gtcaatgaac gttgtaagta acgggctggt ccttggtcta
    45061 gtcacgctgc ttgtatctgt atccagtggc aaatcaataa aaaaatcttt gtacgtatca
    45121 ttcaagttta aatattcctg aaaccaagta ctttcggcag acatatgatt gcagacaaag
    45181 tcgaacatta accgtgtttc gcttctcatt tcttctatat cttcccatgt gcccaaacgg
    45241 tcgttgattg cctgataatt tacaacggag aaaccatcat cagatgtata tgggaaaaat
    45301 ggcaagaaat gtacaactct aaatgtatct gccaaatact tttgataaaa tttcttaaat
    45361 gtacgcaaag ttggttgctg ctcttcaaaa aattgatccc cataagtaat caagaaaata
    45421 tcttcttcgt cccaatgcag tttgcctgcc tggcctttct tctgctgata aacactgact
    45481 ttttgttcaa tcatagaggc ggttttctca gacaaatctg agtcgcgata aatcgcttgt
    45541 aaaagttttg tatacatcgg attccccttt cttttttggg agcgttccca acgatttgat
    45601 catattatgg aaaacgctta ctgtcaatag cattttttta aataattttg atatacacaa
    45661 aaatacaaat aagaaagctt atgtatcaat aattaatagc ttcttaaaaa aatatggtct
    45721 ctcatgatca tgcaagctat tcctaaattt tcaaaatcat agacaaaaaa gaatgtctat
    45781 tgtactatgg aattattcta aaacgctccc aaaaaggagg tgcatataaa attgaaacct
    45841 actatttatg acattgcgaa aaaagctaat gtctcaaaat caactgtctc cagagtatta
    45901 aataaccagc caaatatctc tgataaagca aaagcaagtg tacttcaagc aatcaaagaa
    45961 ttgaattatg aaccgagcaa aattgcaaga ggactgtcag gaaatggttt tgacgcgatt
    46021 ctagcattat ctcatcgtac ttctcatacg acctatggca atcctttttt ttcagatgtt
    46081 attcaatcca tttctgccgt ttctgaacaa aataacttcg acttgattct acaaacggca
    46141 aaaacaccag aagaagagct agaaaaatgc gcgaaaaaga tccaagaaaa aatgatccga
    46201 ggaattatta ttttaagctc tacgatggat gaaacacttc tttttgaatt ggatcaatac
    46261 aatattccta ttgtggtaat cggaaaagtc ggaaacgact acacgaacat ctactcagtg
    46321 gacacggata atttccagga tagttacgat ttggtggaaa cactgatcaa gaatggacac
    46381 cgtcatatcg gctgtctcca tgctccgaca gaagtttatg tatccaatga tcgtctcaat
    46441 ggttaccgtc aatgcttatt tgatcaccac ctagatatcc gtaatgaatg gattatagac
    46501 ggcggctttc gcttagaaga tagcatggca gcaatgaatg atttaatgaa gctacgagaa
    46561 agaccaactg cgattttttc taccgatgca ttaaaatcat tgagtattta caaagtggca
    46621 gaacaatctg gaaagcagat acctgatgat ctttcgatcg caggattcag tgatccctta
    46681 ttgtcctccc tattttcgcc acagttgact cggatagaca ttccgacaaa tcagttagga
    46741 atcaaagcca cagaactttt attccaacta atccaccacc aataccctga agaaaaaaga
    46801 atcattcttt caaccgagat tactctcaca gattcgatcc aacaacaaga aatgtagaac
    46861 agaattataa aagaacagaa acactgagga taagtcagtt actctgttct tttttcaatc
    46921 actcatccct cgttaccccc tcccggtatt ttagcgaatt tttcttattt tccatctgtt
    46981 ttagatagct gtggataact ataatgtttg tgttaaacta ttttttccac agggaagaaa
    47041 aaactatttt taaccacgtt gtgtataagt ttttatagtt cgttttttta aacacattta
    47101 cccttatttc aatccatgtt atttggggat acttatctct aaaacataaa tagaataaca
    47161 gacatgtcta ctggttttgt tttattcgag gaattattca ataatagcta gcaaaatatt
    47221 aaaaataacc gctctatctt cccatcaatt tattttgcat tcaaaaaatg atctatcttt
    47281 acttttgttg attgacttct cttggaagat gatcgttccg ataccttaat tggatacgaa
    47341 ccgatgttgt taagatcctt tcccactttt cttctagtta gacaaattat tttagacaaa
    47401 ccaaaaaaga ggttgtgaca ataatttgtc acaacctctt ttttaaaata tctattttgt
    47461 ttgattgttc attgcgtctt ctgcagccat ttgcgcttca atatctgaaa tactgtagac
    47521 attttcgctt gctacaccga cttcttttgg ttccatgtca cgataacgtt gcataccagt
    47581 accagctggg atgatcttac ctataataac attttctttc aaaccaagaa gaggatcttt
    47641 cttaccgcgg atcgcagcat ccgtcaagac acgagttgtt tcttggaatg atgcagcaga
    47701 taagaaacta tttgtttcta atgatgcttt tgtgatacct agtaagacag gtcgagaagt
    47761 tgcaggaacg cctcctgaga ctagcgtatt gtagttttga tctttaaagt ctgcgatgtc
    47821 taataatgta cctggtaaga tatctgtatc acctggatcc attacacgaa ctttacgcag
    47881 catttgacga accattactt cgatatgctt gtcgccgatt tctacccctt gcatacggta
    47941 aacacgttgt acttcacgaa gcaagtagtt ttcaacagat aatacatcgc gaacttgcaa
    48001 caattgtttt ggatcgattg atccttctgt caatggtgca ccacggtgga tcatatcgcc
    48061 ttctgctact ttcatacgtg ctgtataagg aacagtatac gtacgtgtat ctgtttttcc
    48121 tttgattgtt acttctttgg tacgtgttgc aggatcttct gagatatcga tgacatcccc
    48181 tgttacttct gtgatcactg cttgcccttt cggattacgt gcttcaaaga tttcttggac
    48241 acgaggaaga ccttgagtga tatcgtctcc ggcaacccca cctgtatgga atgtacgcat
    48301 cgtcaactga gtaccaggtt caccgattga ttgagcggcg atcgtaccaa ctgcttctcc
    48361 gacttcaacg tcagagccag ttgcaaggtt gcgtccgtaa caatgtttgc agacaccatg
    48421 ttttgtatta catgtgaaga cagaacggat tgtcactgtt tcgacacctg catcaacgat
    48481 ttgttttgcg atgtcttcgg aaatcaattg gtttcctgca atgatcaatt catttgtttc
    48541 aggatgacgt acttctttac gggtgtaacg tcccactaaa cgatcttcta atgattcgat
    48601 gatttcattt ccctcgcgga tggcttggat ttcaagacct cggtcagtac cgcaatcttc
    48661 ttcacggatg attacatctt gggccacgtc aaccagacga cgagtcaagt aacctgaatc
    48721 ggcagtcttc aaggctgtat cggtcatccc tttacgagcc ccgtgagttg agataaacat
    48781 ttccaagacg gatagtcctt cacggaagtt cgaaatgatt ggcaattcca tgattcgacc
    48841 attaggagcg gccatcaaac cacgcattcc ggcaagctgt gtaaagttgg aaatgttacc
    48901 acgagctcca gaatcagaca tcatgaagat tggatttttc gcttccaaac cttccatcag
    48961 tttttgttgg atgctgtctt ttgcagcatt ccaaacagca atgacacgtt cataacgttc
    49021 gtcatctgtg atcagaccac gacggaattg ttttgtaata gtttcaactt gtttatgggc
    49081 attttcaatg atttcttgtt tttcattcag tacactgatg tcagcgatcc ctactgtgat
    49141 accggcatgt gtcgaatgtt tgtaccctaa gtctttcata cggtcaagca tcttagaagt
    49201 ttctgttact ttgaatcgtt tgaagacttc tgcgatgatg tttcctaagt ttttcttctt
    49261 gaacggtaat actaattctt gctctttgat atgtgcagga atatcagtac cagcttcaac
    49321 aaagtatttg tccggtgttt ggacggtcaa gttgaagtct gttggttcat tcagataagg
    49381 gaattcagga ggcatgatct cgttgaagat gatcttacca actgttgtga tcatcgtacg
    49441 ttctttttgc cattcagtaa atggtttttc acctaatgag ttagggttca caccgatacg
    49501 tgaatgtaaa tgaacatatc cgttgcgcca tgcgataacg gcttcgtttt gatctctgaa
    49561 gaccattcct tcgccttcgc gtccttcttc ttccattgtc aagtagtagt tacctagaac
    49621 catatcttgg gaaggagtaa caactggttt accatcttta gggttcaaga tgttttgagc
    49681 agctaacatc aacatacgtg cttctgcttg tgcttcttca ttcaatggaa cgtggacagc
    49741 catttggtct ccatcgaaat cggcattata agcttcacat acaagtggat gcaaacggat
    49801 tgcgcgtcct tgtactaaaa ctggttcgaa tgcttggata ccaagtcggt gaagcgtagg
    49861 tgcccggttc agcaatactg ggtgttcctt gattacgtct tctaaaacat cccatacttc
    49921 gtcttcttga cgttcgattt tacgtttcgc atttttgatg tttgaagcta gttcgcgttg
    49981 aacaagctca cgcatcacga atggtttgaa taattcaatg gccatttctt ttggaagtcc
    50041 acattggtac atcttcaaga aaggtccaac aacgataacg gaacgacctg agtagtcgac
    50101 acgtttacct agcaagtttt gacggaaacg accttgtttc cctttcaaca tatgagaaag
    50161 agatttcaat gggcggttac ctggtccagt aactggacgt ccgcgacgac cgttatcgat
    50221 caatgcatct actgcttctt gcagcatacg tttttcattt tgaacgatga ttccaggtgc
    50281 attcaagtct aacaaacgtt tcaaacggtt attacggttg attacacgac ggtaaagatc
    50341 attcaagtca cttgttgcaa aacgtccacc ttctaattga accattgggc gtaaatctgg
    50401 tggaataaca gggataacgt ccataaccat ccagcttggt tgatttcctg aagcgcggaa
    50461 tgcttctaaa atatccaaac ggcggattgc acgtgtacgt ttttgtcctt gtgcagattt
    50521 caattcttct ttcaattcgg ctgcttctgc atctagatca acattatcaa gtaattgttt
    50581 aatcgcttct gcacccatag cagcttggaa ttcttgtcca tattgttcac gtttttcgcg
    50641 atattcgcgt tctgtcaaca attgtttttt ctctaaattc gtatttcctg gttcgatgac
    50701 tacatatgaa gcaaaataaa tgatttcttc caaagcgcgt gggctcatgt ctaatacaag
    50761 acccatacgt gaaggaatcc ctttaaagta ccagatatgt gaaacaggag ctgctaattc
    50821 aatatgtccc atgcgttcac ggcgaacttt cgaacgagta acttccactc cgcatcgatc
    50881 acaaacgatt cctttataac ggatacgttt gtattttccg caggcacatt cccagtcttt
    50941 tgtaggacca aaaatccgct cacagaacaa cccttcgcgt tcaggtttta aggtacgata
    51001 gttaatcgtc tcaggttttt ttacttcacc gtaagaccag cttctgattt tttcgggaga
    51061 agccaaacct atttgcatac tttcgaattt atttacatcg atcaaaaggg gttccctcca
    51121 tttcatttaa tggcaaaccg caagacggct gatcttcgac cgccttgcag ctcatagacc
    51181 ggattagtct aaattatctt ctgcggtttc aaagttttgg atgacatcgt ctttttcatc
    51241 ttccacttgt tcagcagctt tcttttctaa ttctttggca gtttgctgtt cggcaaattt
    51301 tgtcaaagca tcaacagtga tcaaatcgtc gtcttcatcg tccatgtcgc gaagttcgat
    51361 ctctgtttct tcgatatcca agacacgcat gtccagacct agtgattgca attctttcac
    51421 caatacgcgg aatgattccg gtacacctgg ttttggaatt ggttcaccct tgacgattgc
    51481 ttcgtatgtt ttcacacgtc cgactacgtc atctgatttg tatgtcaaga tttcttgtaa
    51541 agtataagcc gcaccgtaag cttccagtgc ccatacttcc atttcaccaa aacgttgtcc
    51601 accaaattga gctttacctc ccaatggttg ttgtgtaacc aatgagtaag gtccgattga
    51661 acgtgcatgc aatttgtcat cgaccatgtg agcaagtttg atcatgtaca tcacaccgac
    51721 agacacacgt ccatcaaatg gttcacctgt acgtccgtcg tacagaacag ttttcgcatc
    51781 gctggccata ccggcttcac gaactgtttc ccatacgtct tcatcacttg caccatcaaa
    51841 tactggcgtt gctacgtgga tacctaactg acgtgcagcc atacccaagt gtaattccaa
    51901 tacttgcccg atgttcatac gtgaaggcac ccctaaagga ttcagcatga tatcgattgg
    51961 tgttccatca ggtaggaatg gcatatcttc ttccggcata atacgggata caaccccttt
    52021 atttccgtga cgaccggcca ttttatcccc ttcatggatt ttacgttttt gaacgatata
    52081 aacacgaact aacatgttta cgcctggtga caattcatct ccagcttcac gagtaaagat
    52141 tttcacatcg tgaacgatac cgccgccgcc atgtggtaca cgtaatgatg tatcgcggac
    52201 ttcacgagct ttttcgccaa agatcgcatg caatagacgt tcttctgcag ataattctgt
    52261 tacccctttt ggcgtgactt tccctacaag caaatcgcca tcttggactt ctgcaccaat
    52321 acggatgata cccatttcgt ctaaatcttt taatgcgtct tccccgacat tagggatttc
    52381 gcgtgtgatt tcttcaggtc ctaattttgt atcgcgggct tctgattcat attcttcaat
    52441 atggatagaa gtgtatacgt catcttttac caaacgacgg ctcatgatga tcgcatcttc
    52501 atagttgtac ccttcccaag tcatgaaacc aactaaaacg ttttggccta gagccatttc
    52561 gccttgttcc atagatggtc cgtctgccag agtatcccct ttttcgactt tctcacccaa
    52621 atgaacgatt ggacgttggt tgtagcttgt tccggagttt gaacgacgga attttgttac
    52681 atcgtattta tctaatgcac cgttgtcgcg gcgtacgcgg atttcagaag catcaacgta
    52741 ttcaacgaca ccgtcatgtt tacataacaa agcagctcct gagtcatgcg ctgatttgta
    52801 ttccatacca gtaccaaccc atggtgcttg aggattgatc aacggcactg cttgacgctg
    52861 catgttggca cccatcaagg cacggttgga gtcatcgttt tccaagaaag gaatacatgc
    52921 tgtcgcaacg gcaactactt gtttaggtga tacgtccatg tagtctactt tatcaataga
    52981 tacttctaag ttttcacttt gagcacgagc cataacaacg tcttgagcaa atgttccatc
    53041 ttcattcaat gggctgtttg cttgggctac gatgtaatgg tcttcgatat cagctgtcaa
    53101 gtagtcgatt tggtcagtaa cacgacctgt ttcacggtct acacgacgat aaggtgtttc
    53161 gataaatccg aatttattta ctttcgcata actggacaaa ctattgatca acccgatgtt
    53221 tgggccttca ggagtttcga tcggacacat acggccatag tgggagtagt gaacgtcacg
    53281 aacttcataa ccggcgcggt cacgagtcaa tccgccaggt cctaaggctg aaagacgacg
    53341 tttgtgtgtc aattcgccaa gagggtttgt ttgatccatg aactgtgaca actgagaaga
    53401 accaaagaat tctttgatac ttgccacaac tggacggata ttgatcaatt gttgaggtgt
    53461 caatgtttca gtatcttgga tcgacattct ttcacgaacc acacgttcca tacgtgctag
    53521 cccgatacgg aattggtttt gtaaaagttc accgactgaa cggatacgac gatttcctaa
    53581 gtggtcgata tcatcgacat tgccgatacc ttccatcaag ttcaagaaat agctcattga
    53641 agcaatgatg tcggctggac gaaccgtttt tacagctgct tctggatagc cgtttccgat
    53701 cacgtttact tcacgttcag ggtctcttgg tgaaaatact ttgatgactt ggacagtcat
    53761 tggatctgtg accacaccgt cttctgatgg atagtaagtc actgaattta ggccattatc
    53821 aatgaaagga gctagtgttt ccatgacttg gtgagtcaga actgttcctt tttcaacgat
    53881 gatctcgcct gtttctggat caactaatgt ttcagctaat gtcagattca atagacgtgt
    53941 tttcaaatct aattttttgt ttactttgta acgaccaacg tttgctaagt cgtaacgttt
    54001 tggatcgaag aaacgagcat tcagcaagtt acgtgagctg tctgctgttt ttggttcgcc
    54061 tggacgcaaa cgttcgtaaa cgtctttcaa accttcttct gttcttgagt cgcttgcgtt
    54121 tttatgcaag tctttttcga ctgtattgcg taatgtttcg ctgtcgccga agatttcaaa
    54181 gatcgtatca tcggaaccaa atcctaacgc acgaactaat acggttaaag gaatcttacg
    54241 tgtacggtcg atacgtacat aagagatgtc ttttgcatca gtttccattt ctagccaagc
    54301 tccacggtta gggataacag tagaaccgaa tccttctttt ccgtttttgt cgacttttcc
    54361 atggaaatag acacctggtg aacggactaa ctgagaaacg attactcgct ctgccccgtt
    54421 gatgatgaat gttccttgtt ctgtcattaa tgggaaatca ccgaagaata cttcttgtgc
    54481 tttgatttcg ccagtctcgc ggtttgtcaa acgcaatgtt acatgtaatg gtgcagagta
    54541 gtttgcatca tgcgcacgag cttctgctac tgtatacttt ggttctttca attcataatc
    54601 tacaaattcc aaagatagat tgccattgaa gtcatcgatt ggcaaaatgt cttcaaacat
    54661 ttctctaagt ccctcatcta agaaccattg gtaagagtct gtttgaattt cgatcaaatt
    54721 tggtaattcc aacacttcac tgattcttgc gaaacttcta cgttcgcgat gttttccgta
    54781 ttttactacg tgtccagcca agctcttcac ccctctaaaa tgtcattcaa aaagactacc
    54841 cgatcaattg ttacaataat atttcaaata ttatttttag gtaacaacag acattttttg
    54901 cggcttttag gcaaaaaaaa accaaaaata gaacattctc ttgaaacctt acttcgtgag
    54961 cttctacttt tgtttcctta tattaaagcc gaaacggaca atatttcgtt tctgcctttt
    55021 cttcatcaga tagtttttgc aacttcatat actacactta ttttctataa aagtcaacac
    55081 ttcctggcgt ttcttctgct ttttcgcaac attttcttaa tgttttcaat tttatgtttt
    55141 caattatctg acaattctta attgacagac ctttttatct cggttatact ttagaaaatt
    55201 cattttgtgg aggaacttct atgcgaacca acatcaacca aatcgcacca acacaactga
    55261 ataactttta ctttagctac tttagatagg tttgtattca tcatgatgga tacaaacgtt
    55321 aaacgacagt ttgtatctat gatggctaaa gaactttgta ttgcagcaaa aagccacgta
    55381 gacaaaatgc taagtggctg agcagtgaaa atacaaagta aaagtatcaa gcattctact
    55441 ttttcaattt attttccgac ttttcaatcc atttggacat tttgtctgaa tggatttttt
    55501 gtttcccaaa attaaggagg aaaaagaaat gaaaaaaaat ataatcatcg gattaggcgc
    55561 tgccctgcta ctagctttag gaggttgcgc acaaaaagac aattccgcag aggcatcaga
    55621 tggacaaaaa acaattggcg tattgcaact tgtacaacat aactcgttag atgctgccta
    55681 taaaggattc aaagaaggat tagcagaaga agggtataaa gaaggcgata atctaacaat
    55741 cgattatcaa aatgcccaaa acaatcaaga caacctgaaa agtatgagtg agaaactcgt
    55801 caaagaagat cctgatttgc tacttggaat cgccactcca gcagcacaat ctttattaaa
    55861 tgaaacaacc actatcccga tgactgtcac agcggtcaca gacttggaac aagcccattt
    55921 agtcacatcc aatgaaaaac ctggcggcaa tgtgactggc acgacagata tggtgccaat
    55981 cgaaaaacaa atcggcttac tgttaaatat cgtgccagac gccaaaacaa tcggcatcat
    56041 gtataacaac ggtgaagcaa actctaagat ccaagctgat ttggcagaaa aagaattgaa
    56101 aaaagcgggc gtcaaagtca aagtactgac agcaaattcc acaaatgatg tccaacaagt
    56161 gacgaaaagt ctagctaaag atgtagatgg aatctatatt cctactgata acacgttcgc
    56221 aagtgcggca agtgttgtcg gtgaagtcgc aaaagaaaca aaaacacctg tcgttgctgg
    56281 cgcagttgat caagtcaaag acggcggtct agcaacagta ggaatcgact acgaaagctt
    56341 gggtaaacaa acagggatca tggcagcaaa aatcttagac ggcaagaatc caagtgaact
    56401 tcctgtcgaa acagcgaatg atttggaact gtatgtcaat aaagacatgg ccaaagcatt
    56461 aggcatcaat ccagacagca tcaaagaagc tgaataaaac acaggaggat tctcatgaca
    56521 aatttgctct ctcttttctt atcatctgca tcgcaagggg tcttatgggc cctacttgcg
    56581 attggtgtat acgtcacttt ccgtatcttg gacattgccg acttgactgc tgaaggaagc
    56641 tttcctttag gtgcagggat cgcggcagta agtattacaa atggctatca tccattgaca
    56701 gcttgtcttc taggcttttt agggggtgcg gcagcagggc ttgtttccgg actgcttcac
    56761 acaaaattga aaattcccgc ccttcttgca gggatcatca ccatgactgg tttatattct
    56821 gtcacatccc gtgtgatggg tgcgccgaac atctctttat tgggtcagcc aacgatcttt
    56881 cattgggtcg agtcattcgg cataacaaaa gacaacgctg tactgatcgt cggtctgctt
    56941 tttgctttga tcgttgtatg tttacttgtt ttgttcttac gtacagaaac aggacttgct
    57001 attcgtgcaa ctggcgataa tctggcaatg agcgaagcaa acgggatcaa cacagataat
    57061 atgaagatca tcggttatat gatttctaat ggatgcattg ctctttctgg ctccttgctt
    57121 gcgcaaaaca acggctttgc tgatttaaat tctggtattg gaacgatcgt aattggactt
    57181 gcttctatta tcatcgcaga agttttgtta cgtaaccagc cactatttct ccgtctcttg
    57241 actgtcgttt taggtgcggt catttatcgt tttattttag cgttagtctt cgaactgaat
    57301 gttgaaccaa gtgattcgaa acttgcttct gctttcgtgc tagtgatctg tctttctttc
    57361 ccgcagatcc agcaaaaatt ccatttacct caaaaaaaga aaggcggtag tgtcaaatga
    57421 atgacgtctt aacattggaa aatctccatc atacctttga aaaaggaacg atcaacgaaa
    57481 atcatgtcct gaaaggcatt aatctttcct tagatcccgg cgacttcgtg acgatcatcg
    57541 gtggaaatgg ggctggtaaa tctactttgc tgaacagcat cgccggtaca ttttctgtcg
    57601 atcagggtca aattttattg aatggaaaaa atatcacgaa aaaatctgtt gtcgaacgtt
    57661 cgaaatccat cagtcgcgta ttccaagatc ctaaactagg gacagccgtt cgtttaacgg
    57721 tagaagaaaa tcttgctctt gctatgaaac gaggaaaaaa acgcggcttc ttccgtggtg
    57781 tcaaaccaca agaccgaaca tttttcaaag accagctggt tcggctaaat ttggggttgg
    57841 aaaatcgttt atcctcagaa atcggtttgc tgtctggagg acaacgtcaa gctattacgt
    57901 tattgatggc cacattacag cgtccagaac tgatcttatt agatgaacac actgcagcgc
    57961 ttgaccctgc tacttccaaa acggtgatgg aattgacaga aaagctgatc actgagcaga
    58021 atctcactgc ttttatggtc actcatgaca tggaagacgc gatccgctat gggagtcgac
    58081 tgatcatgct gcatcaagga aggatcgtcg tagatatcca gcaagaggaa aaacagcagc
    58141 tcacagtgcc ccaattatta gcgttgttca aacaaaacag cggcacggca ttaaaagacg
    58201 atcaagtact tttatcttca taatcagaaa gaggatggga caaaaaatga acgcccaccc
    58261 tcttcttttt tctctttcct tctttcgttt ttgctttatg tatcaaccgt tgtttcttcg
    58321 aaaactattt tgttctctcc ttcttcctga tagaatggat gggaaaggag cttgatgcca
    58381 tgacaacgaa agacaaggta cttcaattat tgaaaaagac accagatttt ctttccggag
    58441 aaaagttggc acagcaactg gaagtttccc ggacaagtat ttggaaagcc atcaaagaat
    58501 tggaaaaggc aggctatcgt tttgagcacg ggcctacagg gtatcgttac ctgccctctg
    58561 acgtactaga tgcaaaagaa atccagcaag agctacggtc gtttattcct gatttgaaag
    58621 tacaaacgat gttgacttct gaatctacga tgaaagatgc caaactggca gcagctcaag
    58681 gagattctgt ttcgaagtta tttgttgctg atacacaaga acaagctcgt ggacgttttg
    58741 gacggccttt tttcgctgaa cctggacgag gaatctacat gagtctcttg ctccatccag
    58801 acaaacggtt tgatgaattg cctcaatata cgatcatcgc agccagtgcc tgtgtgaaag
    58861 ccattgaatc tgtaaccggt cgttctgctt cgatcaaatg ggtcaatgat atctacatgg
    58921 atggaaaaaa agtctgtggg attttatctg aagcagtcag tgatatggaa agcggcagga
    58981 tcagtcatat catcattggg atcgggctta atttttctgt tcctcaaaat cattttccag
    59041 ctgatctcca agaaaaagcc atctctgtct ttcccgacgg acaagctagt gtcacaagga
    59101 atcagctaat cagcaaaatc tggcaagaat tgttcactta tctttctcac ccagaaaaag
    59161 cgttggactt ctataaagaa aaatcattcg tattgggaaa aaccgtgtcg ttcaatcaaa
    59221 aaggaacgac ttatgtcggt cttgcaaaag aaatcggtga tcatggcgaa ctgatcgtcc
    59281 aaacaaatga acagaagatg agtttgtctt ctggcgaaat cagtctcaca tctatccgta
    59341 cgcaataatt atcagatttc acaaaaggac acctgatctc atacagtgtc cttttttctg
    59401 aattctcttc aaaagactct ccttattcta tcagctgaca gtttctctat cctctagaaa
    59461 aaggtattct aaaaatatct ataaagcatg gtacactttc tttaaatgaa tcaatgcaaa
    59521 aaacaagaga gtcatcagtt tacacgatca aaagagatag caggccgctt cctttttcaa
    59581 tcttatagat agaccatggg taacgataaa aacaaaaaag aacttgcgac ttattttgcc
    59641 gtaagttctt ttttagctag tgccttaatc tcttaatccc aacaaacgtc tcgcatagat
    59701 cacctgacca gagtgcatag cagcatcatc aataatagaa acgagacgca ttcctcgtgt
    59761 gactggtggt gtccagttct cgtcaattac ttcatctagc tcggaaggtt ccagccttct
    59821 taagtaagaa atagcaaaat cagcagctcc tcgcaagtat cctagcagat cttctatttg
    59881 attagcttgg atctgctttg cttgttccag actatgcttc caatcttgtt cgttatctgc
    59941 tatcgtcatc ggaaaccggc tttcccagtc ttgactatgc caaattggag aagttcctgc
    60001 taaatcagca atctggaaat ctaattctcg agcggtatgc caagccagcc aagtcattga
    60061 tttgatctgc ggggctctat cttccactgg aaaacgattg gcctcctcaa tagagacgcc
    60121 ttcaaacaaa cgttcaaacc gatcgtatgc ccgatccaca ctctcgcata gcatatctaa
    60181 ataatccatt tattttcctc ctttttattt atcctactta ctttttccta attctaggat
    60241 acctacttat atgttactac acacccttat tttttacact ttaacagtca ccatcatcaa
    60301 tagtttggag attgaaagaa aaagatagtg tcgaactatc aattgaacaa gaagcaacaa
    60361 tatgaacgtt tcattaatat tctttaaata aacaatgatt tttcaaacga acagtttaag
    60421 actaggagaa aaagagtata ataggaaaat gtttgaaagg aaaggaaggg gaaaaatgaa
    60481 aaaaagggca agtttactag tcctagttgc tttgttgttc aatatctttt cgtatggtgt
    60541 ggccgtttca gcggaaacat acattcctaa agaccctggg aatatttata atgatctaac
    60601 tggtaactat ggcttgttag gaattgctag tcaattccac gtatttgcta aaaataagac
    60661 aactgtgaat gcacatacag acggaaatat agcaacacat gaacttgatg caaaaaataa
    60721 ttttggtaca gagcttcatg aaggtttatt gaaccaagaa ataaattata tacaaaaaac
    60781 tgattctttc gctaattctt caggcatacc tacaggtagc acaagaatga ataaatttgt
    60841 cgttggcagt aacgtggatg tagcacttca agatggtcat cctacagtca atggatccag
    60901 gcttgatcac ttaactccag atgattttta taaagatcgt gctgggcatg aatatattga
    60961 tttcgagcag gaatttgcta aattgaatgt agcagcaaat gatcttgcaa cgatcactcc
    61021 agctaaaaca tatactgctg cagattttcc agacatgaac aatcggacaa tcgatttaac
    61081 tgatttatca gataccgggt ttttattggt aaatatcgat gcagaagtgt taacgatgaa
    61141 tacgccactt caaatcatta atccaaatga tcaagtagtt gtatttaatg tcatcaacag
    61201 ttcttctgca ttgaacgtac agtcaccaat caaatacaat gatcgttcaa atcatgaaac
    61261 agaagatttt tcggatgcga atatctcttg gaattttgga aatgagatga ctgatttgac
    61321 aatcagtgct ccttttcaag gaacaatcct tgcgcctaat gctactatcc gcattactca
    61381 aaaccaagac ggaacgatta taggaacaaa tgtgatttta gatgcagcta ccaatcgttg
    61441 ggatcctaac gaaatattta tcagcgacaa tggtacagat acgacagaca caagcgacag
    61501 tacagataca tctaccacaa gtgatagctc agattcatca
//
LOCUS       DAFEML010000010        59815 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFEML010000010
VERSION     DAFEML010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.010"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..106)
                     /locus_tag="LP468_000740"
     rRNA            complement(<1..106)
                     /locus_tag="LP468_000740"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(629..1939)
                     /locus_tag="LP468_000741"
     CDS             complement(629..1939)
                     /locus_tag="LP468_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2080298.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1951..3369)
                     /locus_tag="LP468_000742"
     CDS             complement(1951..3369)
                     /locus_tag="LP468_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2080299.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3609..5177)
                     /locus_tag="LP468_000743"
     CDS             complement(3609..5177)
                     /locus_tag="LP468_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2080300.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5181..5591)
                     /locus_tag="LP468_000744"
     CDS             complement(5181..5591)
                     /locus_tag="LP468_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL2080301.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5588..6511)
                     /locus_tag="LP468_000745"
     CDS             complement(5588..6511)
                     /locus_tag="LP468_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL2080302.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6508..7386)
                     /locus_tag="LP468_000746"
     CDS             complement(6508..7386)
                     /locus_tag="LP468_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL2080303.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7373..8710)
                     /locus_tag="LP468_000747"
     CDS             complement(7373..8710)
                     /locus_tag="LP468_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2080304.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8713..9816)
                     /locus_tag="LP468_000748"
     CDS             complement(8713..9816)
                     /locus_tag="LP468_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2080305.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9890..11398)
                     /locus_tag="LP468_000749"
     CDS             complement(9890..11398)
                     /locus_tag="LP468_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2080306.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11364..12056)
                     /locus_tag="LP468_000750"
     CDS             complement(11364..12056)
                     /locus_tag="LP468_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2080307.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(12078..13052)
                     /locus_tag="LP468_000751"
     CDS             complement(12078..13052)
                     /locus_tag="LP468_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080308.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13352..14224
                     /locus_tag="LP468_000752"
     CDS             13352..14224
                     /locus_tag="LP468_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080309.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14682..16880)
                     /locus_tag="LP468_000753"
     CDS             complement(14682..16880)
                     /locus_tag="LP468_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080310.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            17112..18104
                     /locus_tag="LP468_000754"
     CDS             17112..18104
                     /locus_tag="LP468_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080311.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            18164..19585
                     /locus_tag="LP468_000755"
     CDS             18164..19585
                     /locus_tag="LP468_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL2080312.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19578..21077
                     /locus_tag="LP468_000756"
     CDS             19578..21077
                     /locus_tag="LP468_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL2080313.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            21116..22510
                     /gene="uxaC"
                     /locus_tag="LP468_000757"
     CDS             21116..22510
                     /gene="uxaC"
                     /locus_tag="LP468_000757"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL2080314.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22669..23352
                     /locus_tag="LP468_000758"
     CDS             22669..23352
                     /locus_tag="LP468_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL2080315.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23354..24190
                     /locus_tag="LP468_000759"
     CDS             23354..24190
                     /locus_tag="LP468_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2080316.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24201..25955
                     /locus_tag="LP468_000760"
     CDS             24201..25955
                     /locus_tag="LP468_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080317.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26231..26572)
                     /locus_tag="LP468_000761"
     CDS             complement(26231..26572)
                     /locus_tag="LP468_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2080318.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26640..28811)
                     /locus_tag="LP468_000762"
     CDS             complement(26640..28811)
                     /locus_tag="LP468_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2080319.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28980..29879
                     /locus_tag="LP468_000763"
     CDS             28980..29879
                     /locus_tag="LP468_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2080320.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29950..30807)
                     /locus_tag="LP468_000764"
     CDS             complement(29950..30807)
                     /locus_tag="LP468_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2080321.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30792..33494)
                     /locus_tag="LP468_000765"
     CDS             complement(30792..33494)
                     /locus_tag="LP468_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2080322.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33507..34796)
                     /locus_tag="LP468_000766"
     CDS             complement(33507..34796)
                     /locus_tag="LP468_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL2080323.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34946..35992
                     /locus_tag="LP468_000767"
     CDS             34946..35992
                     /locus_tag="LP468_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080324.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35994..38147
                     /locus_tag="LP468_000768"
     CDS             35994..38147
                     /locus_tag="LP468_000768"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL2080325.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38620..40071)
                     /locus_tag="LP468_000769"
     CDS             complement(38620..40071)
                     /locus_tag="LP468_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2080326.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(40068..41792)
                     /locus_tag="LP468_000770"
     CDS             complement(40068..41792)
                     /locus_tag="LP468_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2080327.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41785..42399)
                     /locus_tag="LP468_000771"
     CDS             complement(41785..42399)
                     /locus_tag="LP468_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2080328.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42744..44201)
                     /locus_tag="LP468_000772"
     CDS             complement(42744..44201)
                     /locus_tag="LP468_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080329.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44242..45162)
                     /locus_tag="LP468_000773"
     CDS             complement(44242..45162)
                     /locus_tag="LP468_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080330.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(45174..46121)
                     /locus_tag="LP468_000774"
     CDS             complement(45174..46121)
                     /locus_tag="LP468_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080331.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46600..47319)
                     /locus_tag="LP468_000775"
     CDS             complement(46600..47319)
                     /locus_tag="LP468_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2080332.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47368..49014)
                     /locus_tag="LP468_000776"
     CDS             complement(47368..49014)
                     /locus_tag="LP468_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2080333.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49193..49783
                     /locus_tag="LP468_000777"
     CDS             49193..49783
                     /locus_tag="LP468_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2080334.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49875..51380
                     /locus_tag="LP468_000778"
     CDS             49875..51380
                     /locus_tag="LP468_000778"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL2080335.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51464..52816)
                     /gene="celB"
                     /locus_tag="LP468_000779"
     CDS             complement(51464..52816)
                     /gene="celB"
                     /locus_tag="LP468_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2080336.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52816..53334)
                     /locus_tag="LP468_000780"
     CDS             complement(52816..53334)
                     /locus_tag="LP468_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080337.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53350..53676)
                     /locus_tag="LP468_000781"
     CDS             complement(53350..53676)
                     /locus_tag="LP468_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL2080338.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53689..55668)
                     /locus_tag="LP468_000782"
     CDS             complement(53689..55668)
                     /locus_tag="LP468_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2080339.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55689..56003)
                     /locus_tag="LP468_000783"
     CDS             complement(55689..56003)
                     /locus_tag="LP468_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL2080340.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            56171..56464
                     /locus_tag="LP468_000784"
     CDS             56171..56464
                     /locus_tag="LP468_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL2080341.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56542..57654)
                     /locus_tag="LP468_000785"
     CDS             complement(56542..57654)
                     /locus_tag="LP468_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2080342.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            58041..58220
                     /locus_tag="LP468_000786"
     CDS             58041..58220
                     /locus_tag="LP468_000786"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080343.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58414..58584
                     /locus_tag="LP468_000787"
     CDS             58414..58584
                     /locus_tag="LP468_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2080344.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(59008..59748)
                     /locus_tag="LP468_000788"
     CDS             complement(59008..59748)
                     /locus_tag="LP468_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2080345.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17872 a        12228 c        10465 g        19250 t
ORIGIN      
        1 tctttttccg gtggagcaag ctccggtgga aaaagaagcg ttcgacttgc atgtattagg
       61 cacgccgcca gcgttcgtcc tgagccagga tcaaactctc ataaaaagtt cgaacaatct
      121 tgcgattgtt aagctcaatt tgtttgctag catattgctt gcttgttaaa aatgtttatt
      181 gtcttgaatt gaatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca
      241 aaggtctact tcatcgagag tgtttcccga ttcatttttg gctgccgtag caacttttat
      301 atcatatcag agagacaaac gattgtcaac tcttttttaa aagttttttt cgatttcgtt
      361 tttcgaaatc tttcagcaac tcatttatca taacttatcg tttgttattt gtcaagaact
      421 tttttgaagt ttttttcgat agaatcaagc ttcgcaagtg gttcttttta acgacttagt
      481 tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat aaaatgtttc
      541 aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc aagctaaaat
      601 attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg tttgcagctg
      661 tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt actgcttcga
      721 ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct tctataggct
      781 tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct ggagaaaggc
      841 atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt gattcaggta
      901 tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg ctattttttc
      961 tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca tcaatcatat
     1021 tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa gatttcattc
     1081 gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca ctaactccag
     1141 cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat ctagcaacct
     1201 cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca gacttaatag
     1261 caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt gttgaagaat
     1321 caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact ttttctacta
     1381 atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga aaaatcaaat
     1441 cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt ttaatagcat
     1501 aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg cttttttgat
     1561 cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt ccttttcctt
     1621 ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat ttcatttcta
     1681 cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc cccttgagga
     1741 ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct ccgactaaat
     1801 aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg attgcttttt
     1861 gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa gcattgataa
     1921 tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt tcaattcttc
     1981 accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa tgattgcgga
     2041 tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt cttgtactaa
     2101 aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg ccagcataaa
     2161 tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat ttactccata
     2221 tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca cgtcagtaat
     2281 gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa ataaaagaat
     2341 cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca tacatgaaga
     2401 agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca gctttgtagc
     2461 aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag acattgcttg
     2521 tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta aaatctgatt
     2581 gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag ctaacaaacc
     2641 ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc tttcagtagt
     2701 caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga ttgaaatcca
     2761 aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat acattaaaat
     2821 cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc ggaacgtgga
     2881 caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc catacgggat
     2941 attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat aagcaatctt
     3001 caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca ctaagcaaaa
     3061 tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta actctgagac
     3121 atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg aaatcaagaa
     3181 taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa tcatcaagaa
     3241 actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt agcctatctt
     3301 atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa cagcattttg
     3361 tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt ataactcttt
     3421 ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga cagataaaaa
     3481 acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta cataacaata
     3541 tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc atttattaaa
     3601 gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc agcataactt
     3661 cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt aaaccctcct
     3721 gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt tgatacgtct
     3781 ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt cttcttttct
     3841 gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc tatcatacgt
     3901 aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt ggattcattt
     3961 aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc aaatgctgtc
     4021 tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc gaaggtagat
     4081 tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt atcacaccaa
     4141 tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc ttcaaatgta
     4201 tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat cattatttct
     4261 tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt ccaatacact
     4321 tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct ggtacaaaga
     4381 tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc tgtacattgc
     4441 aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc aagctcgtaa
     4501 ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc tgtaccgcct
     4561 tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc ctccgttttc
     4621 gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt cttctctgca
     4681 tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg ataatcccat
     4741 agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga aggatcaaag
     4801 ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga tgcagtgatc
     4861 aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt gtaaacaaga
     4921 taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt tgtaggattt
     4981 ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt gactaaattt
     5041 ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat aatgtaatac
     5101 cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat aggatttttc
     5161 actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata taaactgaat
     5221 gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt gccaatcaac
     5281 aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt tcctttagca
     5341 gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac ggcaaacaga
     5401 ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga atgatctaca
     5461 gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa agtaactgct
     5521 aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa tagttcccat
     5581 tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt cttttgatcg
     5641 atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt ttcttgtcat
     5701 cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct tcaaataaga
     5761 catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca ggttctgcag
     5821 tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta gatgctgctg
     5881 tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga aaaacggcat
     5941 ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca taggtctgac
     6001 gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct ttttgcaaat
     6061 caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag ttttttaaag
     6121 atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct cctggacctg
     6181 ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag aaaaaagtag
     6241 cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca aaacgattac
     6301 cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg ctttctatat
     6361 attcatcata tcttccttct tttactatca agacctttgg atggctatcc ggcaggcctg
     6421 ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct atagcattct
     6481 ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt gtttccaaat
     6541 atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag aaaagttttc
     6601 tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca gtacgccttc
     6661 gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg gagcgatttt
     6721 ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt aataaaaccc
     6781 atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg ccgctagatc
     6841 aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata agcctcccat
     6901 agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct ccaaataatc
     6961 gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg ttaataaaaa
     7021 ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc aagcatcaat
     7081 cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag aagctaagta
     7141 aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt gagaatgcag
     7201 gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg ctggtactgt
     7261 ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt gtttttctcg
     7321 gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa aatcattcaa
     7381 ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat tgatttgatt
     7441 ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt ccctcgtgat
     7501 tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa aatccttgtc
     7561 tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca tcttgggcca
     7621 tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct aatccataaa
     7681 taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg atccttctga
     7741 atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac ggttctttcc
     7801 ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca ttatccatga
     7861 ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta gatttcaatc
     7921 gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta cgaatactac
     7981 cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg caatttgtga
     8041 tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc ttgattgcaa
     8101 tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg catgattctg
     8161 gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag ttatcaaacg
     8221 ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc aatttaatat
     8281 ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga ggataagcga
     8341 gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca tctaatgtac
     8401 cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa gcataaactt
     8461 ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga tcgtcagaga
     8521 atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa aataaagctc
     8581 ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt gctgcagcat
     8641 caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca aatgtcaaaa
     8701 tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg caccaacgcc
     8761 tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac catctcgctg
     8821 atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc agccttcttt
     8881 tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt gtggaagcca
     8941 ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa caaacatact
     9001 actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta cttgatacca
     9061 tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt ctagaatttc
     9121 tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg ctgcagccat
     9181 caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt ttggatcagc
     9241 ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt ttggatcgaa
     9301 tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt tttcttcact
     9361 aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat ccaaccaaat
     9421 ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg gatggtttgc
     9481 caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg tttctttgta
     9541 caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt caacgctgta
     9601 gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta tgaaatcaaa
     9661 ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta cgacgccata
     9721 gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg ttctttccat
     9781 gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt taaaaattaa
     9841 aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat tactgtgccg
     9901 ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt gctttccagt
     9961 cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat tgcaccgtag
    10021 catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt gaatccaatg
    10081 gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga ttagagaatt
    10141 ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga gagcttgata
    10201 acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa ccatcatcat
    10261 tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca tcttcttcta
    10321 aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt acttgagatt
    10381 tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga taaccgccgc
    10441 cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga ataccttgac
    10501 ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt cttccttgtg
    10561 caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc aaatagccat
    10621 tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta tcaaattctg
    10681 gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa taagaagtga
    10741 aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa ccaactgtgt
    10801 cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact tcataaagct
    10861 catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt cgaatgacta
    10921 agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg tcgatactcg
    10981 cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt aaatattctg
    11041 atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt ttcaacatcg
    11101 caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt gttaatcttt
    11161 cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt ttttcttcga
    11221 tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt aaccaagtga
    11281 ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg ccgcatgcgg
    11341 caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct tttttcataa
    11401 attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc tgtatatgag
    11461 ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc ggaaaagaag
    11521 agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat cagataaatc
    11581 cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc gaataaaaat
    11641 gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat tgggaaaata
    11701 tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct aagataccaa
    11761 ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata tatccagctc
    11821 atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt cgtcaaagga
    11881 aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata cgatgcagga
    11941 ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa attcaaataa
    12001 accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg cagcatatct
    12061 ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc aatcttatta
    12121 gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc tgtactgaaa
    12181 cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat ttctgcaacg
    12241 cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc taatgtctga
    12301 ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa tgtaacatgc
    12361 catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa ctgtgtatcg
    12421 actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt ccagatcact
    12481 tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat tttttcaaat
    12541 cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa tacataagta
    12601 atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt ttgaatcccg
    12661 tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat tggcatcgga
    12721 aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa tgtaaagaat
    12781 gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact tcccattatt
    12841 cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg aagataccta
    12901 aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt attcgttttg
    12961 attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga tagcgtcagt
    13021 tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt gtgaatgttt
    13081 gctgcttatg acttcatgat agataactat ctgaattacg tatataatca tttttaccgt
    13141 aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa agtgtatttt
    13201 ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca cttagcatag
    13261 gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga aacagaaaca
    13321 tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta taggagaaag
    13381 aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct gtatcgttcc
    13441 ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg cgaaaaagtt
    13501 tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt ctacgccgac
    13561 catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga tcgtcagtat
    13621 gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg gtcgaggttt
    13681 cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc caacgttctt
    13741 agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc ctgtggctgt
    13801 taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg atagtttgga
    13861 agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa ttatgctgcc
    13921 attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt actggaacac
    13981 ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac agattctttt
    14041 acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg ttgatgtgat
    14101 tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc ctatgctgat
    14161 tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt ctgtcaaagg
    14221 gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct tcaagaaata
    14281 agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt atttttcgaa
    14341 gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca gccttgagcg
    14401 atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata agaagcgatt
    14461 ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag cctgtctctt
    14521 gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt tctttttgcg
    14581 tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt ctaacttctt
    14641 ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata tttttttcga
    14701 tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt ttgcggattt
    14761 cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt caaccatttt
    14821 tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc tgtttccttt
    14881 ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat cacatctaaa
    14941 gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga caaattttta
    15001 aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa ttgttctaaa
    15061 acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata aatttgtttc
    15121 atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac gagttcattg
    15181 atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc aaacaatgca
    15241 tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat ggcttcaaac
    15301 aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc agcaggaacg
    15361 atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata cagggcttct
    15421 tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt actgatgcct
    15481 atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg gcaatactcc
    15541 atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt ggcttgcatt
    15601 tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc cgtgatcatg
    15661 ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc taacagatcg
    15721 atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa ttgctgcaac
    15781 cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac aaatagcgtt
    15841 tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc tcctatgatc
    15901 cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt tgatttaaga
    15961 ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa taagtaggaa
    16021 agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat tctcagattg
    16081 cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca attattataa
    16141 tctgatttca gtactatata cgttttatct ttttctctta tcactttcag ctgattgtaa
    16201 tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt ctgagtagta
    16261 aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc accaacaact
    16321 tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc tttttcaaac
    16381 attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa taaattattt
    16441 ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag ttgactcaac
    16501 gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt attatcatcc
    16561 ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt ggagtaatct
    16621 gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc atacgtagaa
    16681 aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg cctgagcaaa
    16741 ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg gtaaatgaat
    16801 aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa tattttataa
    16861 aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag gctttcattt
    16921 ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa gaatagcata
    16981 attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat caaagatcta
    17041 ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga aaaagtaagg
    17101 aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt tctcatacga
    17161 cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa caaaaaatac
    17221 gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt ttagtgaatc
    17281 aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact tcatcaaatt
    17341 tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac agtttatctg
    17401 ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac gatggactga
    17461 tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa gaaaaagaat
    17521 ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac gtcactgccg
    17581 atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga catacgaaga
    17641 tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa aaaggggtat
    17701 tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta acaggagatt
    17761 acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct gacctgccta
    17821 ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct gtacatttag
    17881 ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct ccagtcgtct
    17941 cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg tgtcaagaag
    18001 gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct aaaattgagc
    18061 tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca agtaatttta
    18121 tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa aactgacaaa
    18181 agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg aaggcaattt
    18241 tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat tgtttaaagg
    18301 taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga accagcaaga
    18361 taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg atacttccga
    18421 gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg cttatctatc
    18481 tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg caggaatcca
    18541 attcgtggag actgataatt taacagatac tcccccacag agcctcccgg gcaaactgac
    18601 agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca ttccttgcga
    18661 actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg cagaaaaatg
    18721 ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct gttgtagttt
    18781 agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca atcaacggca
    18841 taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg tgatcgaagg
    18901 gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg tcatcatcac
    18961 agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac cgcatacagc
    19021 gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa tgaaagatcc
    19081 tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta tgctttcttt
    19141 acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct tgaatccttt
    19201 tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca gcacccgtct
    19261 gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt taatcactgt
    19321 ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac atgatgatga
    19381 aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta ttcctcgatt
    19441 attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg tgacagatac
    19501 agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat tacaagaaat
    19561 gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta aatcgacgag
    19621 acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg attgatcagc
    19681 aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg ggtgatttga
    19741 aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg acagacgtaa
    19801 ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt gaattggatt
    19861 atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga acatttcaag
    19921 gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta gtacctaccg
    19981 ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa aaacatccag
    20041 atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt tcgcagcttg
    20101 gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat cccaatgccg
    20161 gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa ttcaaaaaaa
    20221 ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat gtttacgatg
    20281 agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa aatgaccagc
    20341 gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt tctgatggtc
    20401 tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg attgctcaag
    20461 gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa gtattgatgg
    20521 cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat gacttcaaac
    20581 agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt aataaagcag
    20641 gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca ggaagctctc
    20701 ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt agtttattgc
    20761 aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat tgccagttgg
    20821 tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg gtcaaggtat
    20881 ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat gcaggcgtct
    20941 tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc atcgctgtag
    21001 ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc atttttaaaa
    21061 acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa gatttatgtt
    21121 tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc attcctacgc
    21181 aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa tttacgaaaa
    21241 caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca aatggcgctt
    21301 gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg attttgaaaa
    21361 atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt acagttggtc
    21421 acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag aaaatgcaga
    21481 gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc gtcgggaaat
    21541 cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag acgacttgca
    21601 ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt cattccgtcc
    21661 agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac tactggaaga
    21721 agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag ggcagcggat
    21781 agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca tcttacgcta
    21841 taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag ctaacaaact
    21901 attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt tgacccactt
    21961 ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta actgtaatac
    22021 acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg atctttcttt
    22081 gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt tgccaaagac
    22141 gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga tgggctgttt
    22201 ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca acgatactcg
    22261 agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg ggaattttgt
    22321 cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat atttccgtcg
    22381 tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg aagatgaaca
    22441 acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt actttggctt
    22501 ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt gaaataacgg
    22561 aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt cttcttctct
    22621 tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat gcctactatc
    22681 catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc cgagacaggt
    22741 tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa ccaagcaaag
    22801 aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct agcttcacag
    22861 tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa aatccaagaa
    22921 gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt ttttgaatgc
    22981 gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg agattactta
    23041 gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat gcgtgcattt
    23101 gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga attgttccag
    23161 accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga tacttgtaaa
    23221 aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc tgataaagtt
    23281 gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa ttatttacaa
    23341 aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt tagatgttcg
    23401 aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata tccaatttgc
    23461 accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg ggagtgctgc
    23521 ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag gatgctatat
    23581 caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt tcaaacagca
    23641 aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg gtagtgtctc
    23701 tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca gaaattctat
    23761 cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg aagcagggat
    23821 caatcatcca atctataact atcagttagc taaacgttta atcgatgaag tagcttcacc
    23881 aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc atgctgatca
    23941 ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag cgcttcatct
    24001 caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca agggctgttt
    24061 agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt acgccactct
    24121 tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt ttatttacca
    24181 agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa aaatatcatg
    24241 caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt tttgccatgt
    24301 caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc gctattgcca
    24361 atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt tatttcaacg
    24421 cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt catgtaaaat
    24481 accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt atcaagaaaa
    24541 tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc cagtcaaaga
    24601 tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc agcggattaa
    24661 atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt cctgttgttt
    24721 tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt ttccgtaaaa
    24781 ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct gcaaaagtga
    24841 tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa cacgaaacaa
    24901 ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta gatatcctgc
    24961 aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg atttgtttga
    25021 ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc gtgatgtatc
    25081 agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg attcctacga
    25141 tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct ggcgatgtag
    25201 aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt tttgaggatg
    25261 tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct ctagaggtga
    25321 aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct acactcctta
    25381 acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat gatcagcctt
    25441 tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct caaaccactt
    25501 tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac gtatcaaaag
    25561 aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac cagcttcctg
    25621 atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc caaaagcaac
    25681 gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta gatgaagcaa
    25741 cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat tacctgacag
    25801 aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag gcagataaaa
    25861 tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa ctgttagctc
    25921 aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct atgacaagac
    25981 ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc tcggtcacaa
    26041 gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg taactcagag
    26101 ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc tatcggcaat
    26161 aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc tgttgtttca
    26221 taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata cggttcaagt
    26281 cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt acttcttctg
    26341 attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg aactcttgtc
    26401 cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg aacagtttgt
    26461 gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg aattctggta
    26521 attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac atgttatgcc
    26581 ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt tcaaaggggc
    26641 tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc ctgaacgcct
    26701 tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc atattgattc
    26761 aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc aacttgatct
    26821 gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc tgtttttgaa
    26881 gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac atttccactt
    26941 gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt cgaaatcact
    27001 acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc gaaattagtt
    27061 tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc agccgctgtt
    27121 ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc ctttgatatg
    27181 acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga atcaacgatt
    27241 ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact gtaagcaccc
    27301 gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc ataatactta
    27361 tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt ttgtaaaccg
    27421 atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc ttgatacatc
    27481 ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact ttgcggttcg
    27541 tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata tacgcttaat
    27601 ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa tcctctaaag
    27661 acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg atctaaagct
    27721 actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa tgcactgttt
    27781 tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata gattttatag
    27841 cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc atcgatcact
    27901 gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt gtcattaaga
    27961 tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat ttttccgttt
    28021 tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg gtgatcgatc
    28081 ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc agacagcgta
    28141 acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc ccataccccg
    28201 ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct gtacttcttt
    28261 tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg gtctaatgtc
    28321 agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc tgatgttccg
    28381 ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa cccgtgatgc
    28441 tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg agaaatcgcg
    28501 tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc gtttttctta
    28561 tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt tgcttgtttt
    28621 gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat cagcaaaatc
    28681 aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa ttgtccgaga
    28741 tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc taaaatgctt
    28801 tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt ttaccatagt
    28861 gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac gttagtgcaa
    28921 gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat gttttaaaaa
    28981 tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc acgatcactt
    29041 tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa tggttagttc
    29101 ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat caacaacctg
    29161 ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc gaagaaacag
    29221 attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt ttatatgaag
    29281 atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca aatgaaccga
    29341 cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa cagcaacgac
    29401 cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt gcaaaaaatc
    29461 catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat cggagatatc
    29521 aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa attggacgag
    29581 atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc gccttgacac
    29641 atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt ttggaaaccg
    29701 gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc gttggagacc
    29761 ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa ctgcacatga
    29821 tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta tgggaataga
    29881 aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct ttttgtgtaa
    29941 tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga taatcccact
    30001 ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt ccatataacc
    30061 acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct gattcattac
    30121 cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga tcagtgcttg
    30181 agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat cttgcccttt
    30241 gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac aatctttatg
    30301 ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa tatgtcccat
    30361 ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg caccgattcc
    30421 tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt gcttcaattc
    30481 cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt agcgttcctt
    30541 gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca aaacgtatcc
    30601 gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc cgattccctt
    30661 caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg gtgttgtggt
    30721 agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca caaattttgt
    30781 tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat tgtccgaatc
    30841 tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag cagattcaat
    30901 atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact agacatattg
    30961 aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt aattgcaaac
    31021 gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc atgatgtttg
    31081 atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt agagaatttt
    31141 tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag acactgtgct
    31201 tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag tagcgtcact
    31261 gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc gactgttaca
    31321 ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt cgtggggttt
    31381 tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact atctgcttcg
    31441 tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc tttcatctga
    31501 ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt catgattgtt
    31561 tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg aaattccaca
    31621 accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc catttcctgt
    31681 agaatactta tttttgctat ttccggtgta tctactaata cttttacttc agagttttct
    31741 ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata ctcatttcct
    31801 atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt tttgcgatct
    31861 tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt ttcgatgatt
    31921 cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc ttctacaagc
    31981 gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac tttgatcatt
    32041 cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa ttggacagtt
    32101 tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg atacttacgt
    32161 ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc gaatcttttt
    32221 ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc agtatttaca
    32281 atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc ggtcagctgt
    32341 tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa acgaggtatc
    32401 atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg atgattttgc
    32461 attaatgtct tccaagcata atctaattga tcatggggat agtttccact aacttcataa
    32521 gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt ggtattccat
    32581 tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc atccgtttct
    32641 tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt ttgaactgct
    32701 tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag ttcatttgcg
    32761 agatggattg cttttgatat atctttttgt accggttgat gatcaacacc attcatcatc
    32821 aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt ccaaaaggca
    32881 agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt ggcaaatagc
    32941 agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta ttgggaagaa
    33001 tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc acggccaaac
    33061 gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat atttccaaat
    33121 gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc ttccatgcca
    33181 atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg caagatataa
    33241 aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg tcttttttct
    33301 ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg aaaactgttg
    33361 aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat cagtcgcatg
    33421 tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga aatgatatat
    33481 actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa gtaatccatg
    33541 actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata attttcagga
    33601 ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc tacaagtaaa
    33661 ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat agctaatgca
    33721 atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc gtactttcct
    33781 tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag ataatcttcc
    33841 tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac attactgtca
    33901 tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt ttgccctttt
    33961 tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt caatttctgt
    34021 gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc cacataacct
    34081 aacacgacca ccgcaaacat attggatggt accagatatc cataacggca agtatcatcg
    34141 ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc tcgcccgtca
    34201 ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg agagtgttca
    34261 tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat aaaagattga
    34321 ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg tattgggtag
    34381 cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt tgtatgatct
    34441 gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg atcgatattg
    34501 atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc ctcatcttct
    34561 tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca catcgctgga
    34621 atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt tgtcaacaga
    34681 gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc cccacatttt
    34741 tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata agccactaat
    34801 aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc caattatgtc
    34861 tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat tatttgaata
    34921 tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa tatttaatga
    34981 tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac caactgaaaa
    35041 agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat tgactgaatt
    35101 agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta aatccgcttc
    35161 tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc ttcttccata
    35221 tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga tgcaagataa
    35281 acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag caaaagagct
    35341 aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac atcttgactt
    35401 actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa aaatctatga
    35461 gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg ctgcctctta
    35521 tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga ctcatccaca
    35581 atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg gtttgacttt
    35641 ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt atatcactaa
    35701 gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga ccatgaatct
    35761 cttgagacag catggttatc atatccctga agatttttca attatcggat ttgatgatat
    35821 ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt ttgaacagtt
    35881 aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc gaccatccga
    35941 tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat aaaatgaata
    36001 tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct aatgggaact
    36061 gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa actacggatc
    36121 aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac cgtcttaccc
    36181 atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg atcaatggaa
    36241 aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa gaaagtatat
    36301 tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct acattgatac
    36361 ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc ggtttacttt
    36421 tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg gaaggaaaaa
    36481 tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata ttgagatttg
    36541 aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac tcgatcccgt
    36601 tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt atcagctcgg
    36661 aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact taccttgctc
    36721 acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac catgatcaac
    36781 aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca caaacatttt
    36841 atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga tctataaaac
    36901 ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt tatcctcttt
    36961 attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg aacagctata
    37021 gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt atgcctggga
    37081 cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga gacttgatgc
    37141 ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat ccaaattatg
    37201 gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac taccacgaat
    37261 cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa gttgccaagg
    37321 tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac tatcaaaata
    37381 tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag ttcagagaac
    37441 cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg caaagcagct
    37501 ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt gagagatata
    37561 aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga ggatatggtt
    37621 ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta gctatttcaa
    37681 accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct gaaatggcac
    37741 agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg ggttaccctg
    37801 gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg ggattttatc
    37861 ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac aaggctgttt
    37921 tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg ccgcagcaac
    37981 aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat tttacccatc
    38041 aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct caccctaaga
    38101 aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa gaggttgtga
    38161 aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc tcatattttt
    38221 cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat tgagaggttg
    38281 tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt
    38341 ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta gtggagaggt
    38401 cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    38461 tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt ttatcgagag
    38521 gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag atttctagac
    38581 aattttttat aagttatttc attacattgg ctttttcttt tatgattctc cactgttttc
    38641 tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga aatacgtggt
    38701 gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt gcaaaagcag
    38761 ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt ttttcgtttc
    38821 ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg acacttcttt
    38881 gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt ccacattgtc
    38941 actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct gctgaagttc
    39001 ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct catcttccag
    39061 atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc gtatatcttc
    39121 cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt tttgagcgac
    39181 ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg tttgatcttt
    39241 tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa attgatgcaa
    39301 ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag aatctgtctc
    39361 ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa aacaacagaa
    39421 gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc cgtaatttcg
    39481 ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag tatcatgagt
    39541 tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc ctattatttc
    39601 ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca gttcttgata
    39661 gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga ttttcttgag
    39721 gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg cgcctaattg
    39781 catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa attcaaaatt
    39841 atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg gcattgtcac
    39901 atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt ctttggcatt
    39961 ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct tttttaaccc
    40021 attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca tccctccttg
    40081 aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat ataataactg
    40141 ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga accgtgaagt
    40201 tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc agtcatccct
    40261 tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac tttgacactt
    40321 agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc aactaatggc
    40381 tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat aaaatgatag
    40441 gctactcgat taggataacg catttgatac aaatagacat atttttcgca aaagtccagt
    40501 tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa agcggaaaac
    40561 gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat tcggatatat
    40621 tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg catatgtgcg
    40681 tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat gctatccaac
    40741 atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt tatgtcgatc
    40801 cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat agatacttgc
    40861 tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc taaaataatg
    40921 ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact ttttttatct
    40981 agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa attgtttttt
    41041 tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat gatcatttct
    41101 tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag tcgatttgtc
    41161 gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc taaaatcata
    41221 tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc tccttgtgtg
    41281 ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt tatttcccca
    41341 cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac gatatatatc
    41401 gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa agaaactaat
    41461 tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat gggttttgtt
    41521 aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt tttgatgatc
    41581 ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc atcacttgtc
    41641 atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat aacggtagca
    41701 gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt tagtaaggtt
    41761 ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat ctaattcttc
    41821 acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga caccaaacag
    41881 gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa taattatttt
    41941 tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca gattaggaac
    42001 agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa ataggcagag
    42061 caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga tttgaacaga
    42121 taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa atagcagatt
    42181 gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga tttctttata
    42241 ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac ctaatccaaa
    42301 gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta taatgaccca
    42361 gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc caaacattaa
    42421 gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga cctgattatt
    42481 agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg aataccgagg
    42541 gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag tttcgagtag
    42601 taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc ttaataccga
    42661 gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt cttttgtcac
    42721 aacccctttg tctttattca ttattattct tgtcggaact catcatattg tttttgcatt
    42781 tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt cggtaatgtt
    42841 tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat gacattagaa
    42901 atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa aatcggtgaa
    42961 gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt aatagactct
    43021 tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt atttggctga
    43081 taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca tgcttctccc
    43141 tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag ccctagaagt
    43201 tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc catttgtgct
    43261 tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg ttttgctgca
    43321 tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg cattagccaa
    43381 gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg aatgagtcct
    43441 tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt atcgtattgg
    43501 ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt attccctaaa
    43561 ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc tgccgtgttt
    43621 ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga ttggattcca
    43681 tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac ttgttgagca
    43741 aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt tcctttaata
    43801 tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa ttcagtcaaa
    43861 tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc gatatcataa
    43921 ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca gccaatgtaa
    43981 ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac ttccatcaat
    44041 tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc cgaattgcta
    44101 gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc caacaacaac
    44161 gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc tcctaatttt
    44221 atgatttata tttttgtttc tttattcttt tactccgccg attgttagac ctttgacaaa
    44281 atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga ctacgatcgc
    44341 cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc ttcctgctcc
    44401 tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat actgtagtgg
    44461 aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc agtaacccaa
    44521 tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggcaaaa cgatctgaac
    44581 aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg aatcagagac
    44641 cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag ccattggcaa
    44701 gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa gataattggc
    44761 caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa aacgacggaa
    44821 tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc tattgatcag
    44881 tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt tatcctgcat
    44941 ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa aactgtaccc
    45001 gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata taaatggcaa
    45061 aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag ccgtcttatt
    45121 gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc tccttagaat
    45181 aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa caagacaaag
    45241 ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc tgtggatgtc
    45301 aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc accggaattc
    45361 ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac ggctaaaatc
    45421 gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat ctgctgccat
    45481 ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc cataacagat
    45541 gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa caccaagata
    45601 aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg tccagtgatc
    45661 cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta actgataatg
    45721 acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac gagtcgttta
    45781 tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt caaaaggata
    45841 aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc cgaagaaaat
    45901 aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc caagaaccca
    45961 tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg tatgtaaaag
    46021 aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt ataacgccat
    46081 agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc cctttcgatt
    46141 cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa gtatagggaa
    46201 aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt attagagaaa
    46261 aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagct
    46321 gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt attagggaga
    46381 tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta acaaaagtct
    46441 tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac ggaaataagc
    46501 cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt tcagatggcg
    46561 ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc tcacttgttc
    46621 tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag gcagccaaaa
    46681 ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt tgaccattcg
    46741 cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag tttctgtctc
    46801 ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc catcaataat
    46861 cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa cctcagctag
    46921 atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca ccccgtcatt
    46981 cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa aaagatcttc
    47041 ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat cctgagtagc
    47101 agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat acgtaatgat
    47161 ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat cgcttttcac
    47221 cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt ctttgcggct
    47281 gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc atttcaaaag
    47341 agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc gtaaacgcgc
    47401 tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat aaccatacac
    47461 taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt tgctatcttc
    47521 gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca taatcaaggt
    47581 aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc gggctacttc
    47641 atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg tcgccaataa
    47701 agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt tcactagaaa
    47761 cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca gcatgttgga
    47821 aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca gtacattact
    47881 tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta acataacacc
    47941 aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg tcaattttgc
    48001 cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc cagtagacgc
    48061 gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg cactaaaaat
    48121 cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca tgatcttcat
    48181 aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa taataaacgg
    48241 aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta ttttgttttc
    48301 gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat acaaaaggac
    48361 aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga ccgccgtcac
    48421 atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat aaaaaatacg
    48481 tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat tgccttgcaa
    48541 ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca aagaacgcat
    48601 cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag aggcgatgta
    48661 catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac ggataaataa
    48721 tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt ttgcaatcgc
    48781 agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt atcccatatt
    48841 gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg gaatgatata
    48901 gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag agcctcgtgc
    48961 cattttttct tgcggtgtta attgatctaa tgctggtttt ctttgattat ccatcggtca
    49021 gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga aactggcaat
    49081 cgattttata taacttttat aagaacaatt gtttttttga attcggtttc gtttttttgg
    49141 taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat caatgacaca
    49201 agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag ttggattgaa
    49261 ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg gacatttagt
    49321 tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc ttatgatgct
    49381 gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag cgggaagtct
    49441 gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct cacatttctt
    49501 ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt acacagtcgg
    49561 ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt ttcggcttcc
    49621 aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt attatgtttt
    49681 tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat tgtttatgaa
    49741 aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga ttttgtcata
    49801 gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa ttgaataaag
    49861 cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta ttaaaagaaa
    49921 atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca gaaaaagctg
    49981 aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg tttttctgta
    50041 aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt attcaatatt
    50101 atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg gatatccgta
    50161 aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa ttgaaagtga
    50221 tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa gcaatcttgg
    50281 atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg ttagatggca
    50341 aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat cgtatgatgt
    50401 cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca caagcttaca
    50461 aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat atctcgcctg
    50521 accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc aagcgacaat
    50581 tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt gatttactta
    50641 gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg gaagaaagca
    50701 attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct tctcatgaag
    50761 atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga ttcaaccaag
    50821 aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt caagatgcac
    50881 aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc caatccaatg
    50941 gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca ttgctgaaat
    51001 ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc ccaggaaaca
    51061 aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct gacatcgcct
    51121 ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa gaaatcaatg
    51181 aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct gaagcgattc
    51241 gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga aaaggcgtgg
    51301 atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat gcaatcgtga
    51361 agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt ctaagaaaaa
    51421 aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt aacttttcac
    51481 tagctaattc tgctgccttt tctctttctt catttaataa tttattatca tagaatttga
    51541 taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac acagcagctt
    51601 tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc cacggcatct
    51661 gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt gtagcagaag
    51721 ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt ggcatcccga
    51781 aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt cctaacactt
    51841 tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa gtcgcacctg
    51901 atccaccaac ggttacataa gaattgttga attctcctgc caacggataa tttgcgcctt
    51961 gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg atgatattcg
    52021 ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc atgacaccaa
    52081 gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt ttgaagatat
    52141 ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca atgacaaatg
    52201 ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct ggcattttta
    52261 tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc gacataataa
    52321 tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc ctaataccat
    52381 ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca tcagtcatga
    52441 tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc gtgagcggat
    52501 taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca aacacaatgg
    52561 caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac aagtcactaa
    52621 ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat ggcaaaatat
    52681 ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc cccgctgcca
    52741 tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc aggtatttct
    52801 gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt catattgttt
    52861 aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat actgtataaa
    52921 tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc ctccattgtt
    52981 atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg gaatcactaa
    53041 taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt tcgtttggtg
    53101 ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa tcagaatcat
    53161 cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt gcatgttcat
    53221 gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat acatgttttt
    53281 caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct gcacaatgat
    53341 ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa cttccaataa
    53401 tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca tttctatttt
    53461 tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat gaagaatctc
    53521 ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac gcatcgagcg
    53581 aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat caaaagaagt
    53641 cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt attcgatcag
    53701 tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt cctgctgtac
    53761 ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc cttcattttc
    53821 gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat cccactgcat
    53881 cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa cagcgggatg
    53941 tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt gctggatctg
    54001 ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt gcagcaaatc
    54061 atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt tttcagacaa
    54121 ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg gtctatctga
    54181 ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat catcttcatt
    54241 caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa gatcaataga
    54301 agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat agccttttac
    54361 acttaccact gtaatatttt taccgaattc actgactacg cgattcttta atagttgggc
    54421 actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag ctctttcttt
    54481 ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat tgatggtata
    54541 gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga ctttgggatt
    54601 ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc tcaatcgaat
    54661 catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct ctactaatga
    54721 aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg atagttcctg
    54781 atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca aataagcaat
    54841 ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga tccgctgcgc
    54901 cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct tgatttcaaa
    54961 cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct gtatgataaa
    55021 atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga ctagctcttc
    55081 aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg aatttccata
    55141 atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt ccccttcgat
    55201 ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca atcgctcctt
    55261 gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt ctgccaaatc
    55321 atccataaaa agaatggcat cttccaaaag caattggttc aatatatact tttgtcgatc
    55381 ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt cttgccgact
    55441 caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat aacctggttt
    55501 agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca agtaattacg
    55561 gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga catactcctt
    55621 cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta tcatccactc
    55681 ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc tgtagggatt
    55741 gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc tcctaatttt
    55801 ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc aaaatcacta
    55861 ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac ctcttctctt
    55921 ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat tcctgccgca
    55981 caaataatca atgctttttt cataaatcaa tcactccttt tatttttata aaccaagcat
    56041 atcttataag cgttttctat tcaaaatata tatttccgta gcattgcgga aaaaatgtgt
    56101 atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa ttttttcagg
    56161 aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg gacaagccag
    56221 aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg cagaagaagg
    56281 aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt tactgatcga
    56341 ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga tggctcaaat
    56401 aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca ctgatttacc
    56461 gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt cactttttcc
    56521 ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta tttttcggat
    56581 aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga tattctcaaa
    56641 aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg ccaaagcacc
    56701 aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag ctagaccacc
    56761 taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata aaacacatcc
    56821 aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg acatcaatcc
    56881 atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct gaaaagggac
    56941 atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca tccaaatttt
    57001 ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt ctttgttctt
    57061 ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa ataataagct
    57121 acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat aaacaataaa
    57181 gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag cggttgccat
    57241 taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc atttgatcag
    57301 ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta tgatcgaatg
    57361 ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga ataaaaccac
    57421 agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa aacaaatggc
    57481 aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc acttttcttt
    57541 tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt gtagagactg
    57601 ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag tcatctatga
    57661 caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca actatttttc
    57721 ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc accacaaaat
    57781 aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt ctgagatcaa
    57841 tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag aaaaaaacat
    57901 tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt ggttctgctg
    57961 tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa accattgtcc
    58021 actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag cgctatacct
    58081 gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca aggcactcga
    58141 tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg tcgttatttt
    58201 ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg aaagagttga
    58261 gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg gttgtgaatt
    58321 tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg gcgagacaga
    58381 aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa ctatttcctt
    58441 agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc cacctacttt
    58501 cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt acttggtttt
    58561 tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct ttccgagaca
    58621 aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag agaaaaaatt
    58681 acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat aaacttgagt
    58741 cattaggcaa aaaacactgc gaaactcaag aatgattttc gcagtgtttt tgtatatttt
    58801 ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc acaaaattgt
    58861 ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata tttgtttgta
    58921 taccccttct aaaatcggta gtttccattc aattgatggg tactagttga ttttaaaaac
    58981 tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa attttatact
    59041 gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga tggtttctcc
    59101 agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta tatctgagct
    59161 atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt ctttttcgat
    59221 cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag tttctaccag
    59281 ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc ctgtggttag
    59341 acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc cttgcaggac
    59401 ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa gtcgattttc
    59461 tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga ttggtgtcgc
    59521 atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc ctggtgctaa
    59581 gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca gaacggttcc
    59641 attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt ggtcatcgat
    59701 ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt ctaccaccgc
    59761 tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat acccc
//
LOCUS       DAFEML010000011        56412 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFEML010000011
VERSION     DAFEML010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.011"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..305
                     /locus_tag="LP468_000789"
     CDS             <1..305
                     /locus_tag="LP468_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2080346.1"
                     /translation="ITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGIL
                     RRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(1171..1701)
                     /locus_tag="LP468_000790"
     CDS             complement(1171..1701)
                     /locus_tag="LP468_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HBL2080347.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1698..2315)
                     /locus_tag="LP468_000791"
     CDS             complement(1698..2315)
                     /locus_tag="LP468_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2080348.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2897..3118)
                     /locus_tag="LP468_000792"
     CDS             complement(2897..3118)
                     /locus_tag="LP468_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HBL2080349.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
     gene            complement(3296..4828)
                     /locus_tag="LP468_000793"
     CDS             complement(3296..4828)
                     /locus_tag="LP468_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2080350.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4964..6049)
                     /locus_tag="LP468_000794"
     CDS             complement(4964..6049)
                     /locus_tag="LP468_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2080351.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(6064..6783)
                     /locus_tag="LP468_000795"
     CDS             complement(6064..6783)
                     /locus_tag="LP468_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL2080352.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6780..8090)
                     /locus_tag="LP468_000796"
     CDS             complement(6780..8090)
                     /locus_tag="LP468_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL2080353.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8117..8707)
                     /locus_tag="LP468_000797"
     CDS             complement(8117..8707)
                     /locus_tag="LP468_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HBL2080354.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(9025..10086)
                     /locus_tag="LP468_000798"
     CDS             complement(9025..10086)
                     /locus_tag="LP468_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2080355.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10654..11721)
                     /locus_tag="LP468_000799"
     CDS             complement(10654..11721)
                     /locus_tag="LP468_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2080356.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11741..12220)
                     /locus_tag="LP468_000800"
     CDS             complement(11741..12220)
                     /locus_tag="LP468_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HBL2080357.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12237..12698)
                     /locus_tag="LP468_000801"
     CDS             complement(12237..12698)
                     /locus_tag="LP468_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2080358.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12712..13962)
                     /locus_tag="LP468_000802"
     CDS             complement(12712..13962)
                     /locus_tag="LP468_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBL2080359.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14340..15791)
                     /locus_tag="LP468_000803"
     CDS             complement(14340..15791)
                     /locus_tag="LP468_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2080360.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(16112..16876)
                     /locus_tag="LP468_000804"
     CDS             complement(16112..16876)
                     /locus_tag="LP468_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL2080361.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16904..17602)
                     /locus_tag="LP468_000805"
     CDS             complement(16904..17602)
                     /locus_tag="LP468_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL2080362.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17614..18393)
                     /locus_tag="LP468_000806"
     CDS             complement(17614..18393)
                     /locus_tag="LP468_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL2080363.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(18409..19353)
                     /locus_tag="LP468_000807"
     CDS             complement(18409..19353)
                     /locus_tag="LP468_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2080364.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19399..20178)
                     /locus_tag="LP468_000808"
     CDS             complement(19399..20178)
                     /locus_tag="LP468_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080365.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(20558..22633)
                     /locus_tag="LP468_000809"
     CDS             complement(20558..22633)
                     /locus_tag="LP468_000809"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL2080366.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22635..23552)
                     /gene="glyQ"
                     /locus_tag="LP468_000810"
     CDS             complement(22635..23552)
                     /gene="glyQ"
                     /locus_tag="LP468_000810"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL2080367.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(23938..24756)
                     /gene="recO"
                     /locus_tag="LP468_000811"
     CDS             complement(23938..24756)
                     /gene="recO"
                     /locus_tag="LP468_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL2080368.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(24899..25798)
                     /gene="era"
                     /locus_tag="LP468_000812"
     CDS             complement(24899..25798)
                     /gene="era"
                     /locus_tag="LP468_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL2080369.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25813..26208)
                     /locus_tag="LP468_000813"
     CDS             complement(25813..26208)
                     /locus_tag="LP468_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL2080370.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(26192..26668)
                     /gene="ybeY"
                     /locus_tag="LP468_000814"
     CDS             complement(26192..26668)
                     /gene="ybeY"
                     /locus_tag="LP468_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL2080371.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26697..28889)
                     /locus_tag="LP468_000815"
     CDS             complement(26697..28889)
                     /locus_tag="LP468_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL2080372.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28913..29884)
                     /locus_tag="LP468_000816"
     CDS             complement(28913..29884)
                     /locus_tag="LP468_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL2080373.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30589..31968
                     /gene="brnQ"
                     /locus_tag="LP468_000817"
     CDS             30589..31968
                     /gene="brnQ"
                     /locus_tag="LP468_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2080374.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(32124..32570)
                     /locus_tag="LP468_000818"
     CDS             complement(32124..32570)
                     /locus_tag="LP468_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL2080375.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(32597..32773)
                     /locus_tag="LP468_000819"
     CDS             complement(32597..32773)
                     /locus_tag="LP468_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL2080376.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(32935..33363)
                     /locus_tag="LP468_000820"
     CDS             complement(32935..33363)
                     /locus_tag="LP468_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2080377.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            33455..34315
                     /locus_tag="LP468_000821"
     CDS             33455..34315
                     /locus_tag="LP468_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL2080378.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(34409..34759)
                     /locus_tag="LP468_000822"
     CDS             complement(34409..34759)
                     /locus_tag="LP468_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2080379.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(34775..36502)
                     /locus_tag="LP468_000823"
     CDS             complement(34775..36502)
                     /locus_tag="LP468_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL2080380.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(36715..37641)
                     /gene="trxB"
                     /locus_tag="LP468_000824"
     CDS             complement(36715..37641)
                     /gene="trxB"
                     /locus_tag="LP468_000824"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL2080381.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(37786..39222)
                     /locus_tag="LP468_000825"
     CDS             complement(37786..39222)
                     /locus_tag="LP468_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2080382.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(39219..40622)
                     /locus_tag="LP468_000826"
     CDS             complement(39219..40622)
                     /locus_tag="LP468_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2080383.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            40852..41754
                     /locus_tag="LP468_000827"
     CDS             40852..41754
                     /locus_tag="LP468_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2080384.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(41795..43681)
                     /locus_tag="LP468_000828"
     CDS             complement(41795..43681)
                     /locus_tag="LP468_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2080385.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(43778..44630)
                     /locus_tag="LP468_000829"
                     /pseudo
     CDS             complement(43778..44630)
                     /locus_tag="LP468_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(44965..46749)
                     /locus_tag="LP468_000830"
     CDS             complement(44965..46749)
                     /locus_tag="LP468_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080386.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(46749..48500)
                     /locus_tag="LP468_000831"
     CDS             complement(46749..48500)
                     /locus_tag="LP468_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2080387.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(48642..48866)
                     /locus_tag="LP468_000832"
     CDS             complement(48642..48866)
                     /locus_tag="LP468_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL2080388.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            49117..50703
                     /locus_tag="LP468_000833"
     CDS             49117..50703
                     /locus_tag="LP468_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL2080389.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            complement(50769..52544)
                     /locus_tag="LP468_000834"
     CDS             complement(50769..52544)
                     /locus_tag="LP468_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL2080390.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(52755..53657)
                     /locus_tag="LP468_000835"
     CDS             complement(52755..53657)
                     /locus_tag="LP468_000835"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL2080391.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            53936..56281
                     /locus_tag="LP468_000836"
     CDS             53936..56281
                     /locus_tag="LP468_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2080392.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
BASE COUNT        16724 a        11737 c         9136 g        18815 t
ORIGIN      
        1 ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt aaccaacatg
       61 atattgatat atattttgcg gaccctggaa caccttctca acgcccatta aacgaaaatt
      121 ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat agattttaga gaagtgaatc
      181 agacatttat ttccagtgtc agcaatcaac gcaatcatat tccaagaaaa tcattgaatt
      241 acagaacacc aatcgaaata tttttgagct atgtacaaga agcattttat tctagcttaa
      301 tttgacaaat catataattt aaaattaaca ttgattctcc tatgaaaata tcttttacct
      361 ttctcctgtg aaaaggaaat ttcctttttt atagtgttat tgatataatc agaatattca
      421 tcaaactctg tatctggagt taaaaatcta cagtaacatc tataagcttt gctagtaatc
      481 ttcttgggtt ctctctccat tgtcaagcaa catcaaaaca cctacttact attcgattct
      541 tttctgccaa aaacgagtca gcatcactca caacttatgt gttgctgact ccgactagtc
      601 ctttgttcaa tatcaactta ttaaacagat ataatatttt tctttatttc gtatactcca
      661 agacttccat ctttctttca tcttatctct gaaaaaaaca cagcaaagtg cccttaataa
      721 atatacatta gaatttgcaa attttttcat cttaagatat atcctattca tattctttac
      781 aatcctaatg ggtgattaca aatctattta gttcaagttc tacattataa acacctttct
      841 tgatagtatc atctgctgca caagcgatgt cgatccactt attaggggat ttacgtgctc
      901 aaaagtggct attccttttg ggaagtccat ccataataat ggtccatgga tttttttagg
      961 gtcttgtcgt tcaaatttct caaaaacttt attatacttc catagtttta taattatttg
     1021 gtttcacttt ggctcgttca aacaccaact tgtatttctt ttcaacgttc gaactggagc
     1081 cccccctata atctcattat tattttcatg actttttact accgtggaat tacaagcaac
     1141 aacaatatta tctgctaaat gaacaccttt ctatatcacg ctttttgctc caatccaaca
     1201 atgtttacct ataactattt tattattttt attcaaaatc ctatgagtat tcaattcaaa
     1261 aatcgtatgt gaatcggtat ccataaataa tgtatcccac gatactgtac agccatcttt
     1321 gaattgaatt tccttaaagc aaattatact catttttcct gtcgaattaa actttgaccc
     1381 aatatctaaa actgcatttt tccttatgtc aatatgagcc ccttgtgcga taaacgctgg
     1441 cccttgtatt cttagtattc cttcaatact tataatcgtt tcttcatttc ccgcagtatt
     1501 taatactgga aagcccaaat aaactatttt tccagattgt aatactatct caattttccc
     1561 tctcgatttg cgtgtaatcc gtactttacg atgcaccaaa ataggtaatc tccacgcatc
     1621 tgaaatatga agaaatttat aattgaagta tatcgtttta ggtaaattta atatattctt
     1681 tattatcaat ccgagtctca tctttcacca tctctttttg taatcaaaat tagtttataa
     1741 aggattacac ccaatatacc gcccaacgta ttatatacaa aatccgaaat ttgaaacgtt
     1801 cctagcctca aaaaaagttg taaaaattca attattgctg aaaaataaaa tgcaattttt
     1861 cctccatata ctattgagga ccatattttg ggtttcttta tattttcata tttaatagac
     1921 attaccatat aaacatatgg aataaaaaga ataatatttt ctaaacacgc tgtagataac
     1981 tcttttgttc cagttgttgt attatactta taaatccacc agtctcccat aacatcagat
     2041 aaaggattta accaaattgt tcgattgatt aatgttgtaa ataaaatcat cgcagtatag
     2101 aatatcaaag cacaaacttt tctatatttt ctatccttct ttaaatgaag ataaagttcc
     2161 attagtatac gtttatagcc ctcacctgca gcaatgccat ctgttgcata cataaaatag
     2221 accagtccta aaattgtcaa taaaacagca aacccaaagg gttcatataa tttatataat
     2281 atatctgtaa taatttctgc aatcactatt atcataatta tttctccaat atcaagtata
     2341 cacttatcgc ttccaattac acatgatcat attagagtgt attatcacat tctctaatat
     2401 tcaatttatt tttcctaaaa tattcgaaat aatcgtcttg ataacgagta agtattttta
     2461 tacgattgat aacatagtaa caatattttt aattatagta aaaaatcatc tgcctttttc
     2521 atccacctaa tcttattttt cattttattc aacatcctta aataaacttc cgttcctaag
     2581 ctctataata tcttcttaaa aaataatatt atggtgtcgt tttcaaactc gtaatctttt
     2641 acattggaaa aatacatact tttctcaatg tagcaactcc tatctcacag tattcaaaaa
     2701 ttcttcaata ttatgaaata cttgtgcatg ttctttaaat accttgtcag tctgtttata
     2761 atcccctact aaattttgca ttgctcccaa ctcttcgaca aattgtcatc tccatctgta
     2821 aacagcccta aaaactcata taatgctttt tcatcaatat ttttcccata ttattctcgg
     2881 tatagtttca caagttttac ggattcttca tattgtttat ctttttataa tattcatcta
     2941 gggacataat tacttttgct agatttcctg caacaacaca atcgtctgat acgtccttgt
     3001 ttactaaact atttgcacct ataactacat tatttcctat atgtacaccc tttagtattc
     3061 tagacttcat tcctataaaa acattattac ctattttgat cctctccgat gatcccaaag
     3121 cttctccata ctacttttaa aaccgatcaa tcataaacat gagtcaaaat tgtaactcct
     3181 tcatatcatc tccaatttca acaagagtct tcgttggaac aaaaactata catcgttcgc
     3241 ctattcggca gcctaaaaat tgtagttact ttatatatca ttctgatgtc tcttctcatc
     3301 tttttaccaa taccgacgta agaactttca aaatatactt aaacttctta ttacggatat
     3361 taaacagaag aataactaaa atcgatatga caaccgatat aactaaattt atcactaaac
     3421 ttatcacttt gaaatttccg atattaacat acgaacaagc aaaataactt aaataagaag
     3481 caacaaaagc tattacacac aaacttatga gcttccaaac atatttacct gccgattcaa
     3541 atttaaatat attttggaaa acattatata ataaccaggg taaatcaacc aacaatactg
     3601 aaacaatggt tgccgccaaa actccatata atccgaacca attaacgagg atgatattta
     3661 atacaatgtt tatcattgct gtaattaatg gtctaaacct gtctgcgtac catattccag
     3721 cagcatcttt gtataaccca attaactgat caatttcata taagaaaaaa tgaactatca
     3781 taaatataac aaatgaaata ctcataagat tatcacttcc cacccagata atcatgaacg
     3841 gctgaaataa tgtaataaag catgcacaac taattgccag aaaccaacct ataattgttg
     3901 taatatcaca aaaatctata taattttttt cttgactttc tacaataaga ctgttaccta
     3961 tacctgctat acatgattca taaattattg caaatatact cattatggca gaaataataa
     4021 agtaataatt ctgataaatc gcaagtactg aaagacctaa gaaagatgaa ataataattg
     4081 aatctgaaga tcgtaatatt gtaccgccta ccttgtttgt aactaatcct tttacttttt
     4141 ttataatatc gtcaatagtt tctttctcta actcaccaac aggagtataa tcaggataca
     4201 tcttttgaga aacaacagca cacattaagt taagaactat ttgtcccaaa atagaagcca
     4261 ataaatacaa atagtaattt tttaagaaaa tcagaacata tgcctgcatt acaaattgga
     4321 atgtaaaagt aattagcata gacacgttaa ttacatcatt tctttgatgt gcatatatta
     4381 gactctttct atatgaaaat aaccaatacg acaaaacagt atttatcaaa tacattaaat
     4441 acaaaactgt catatttaaa tttccaggaa tcgaaccttt aactaaaaat ctcaaaaaag
     4501 gaatgcataa caatcctaat gtaaacacta tccatccaat aattgaaaag tactttttat
     4561 atgcgttcag taaagcacaa atctcttttc tattgtcttc tgctataggt ttatacatac
     4621 ttacagttag tgcagcacct attcccaatt ccgctaaatt taacatttga aatatagatg
     4681 tgaacaggtt gttcaatcca gcatactcca ttcccatctg ataaatcata agtgtacgca
     4741 taaaaaaggg aatgataatc tgatataact taaaaattgt tccagtaatt atattccttt
     4801 tagcattttg tttacgatta attatcatat catatggctc caaactttct attttttatt
     4861 gttacctaat actatataat ttctaaaatc ttgaaatgta ataggtttct tctagctctt
     4921 tgattaatta cgctaatttt catgtttgga caaccacaaa aaactataca ttttcaatca
     4981 aagcaaccca ttgttttgta atttctttca aattaaattt ttgtacatta ttatatgcgt
     5041 tcagtgacat tctcattgct aaatcagtat tcttagtaaa cattatcatg ctcttagcta
     5101 attggtctat attcttatct tcaaccaaca tcccattaaa attatgatgt accaaatctc
     5161 tcggaccagt tttacaatca taagaaataa ctggtaatcc ataagactgt gcttctaata
     5221 taaccatagg aaatccttca taaacagaac taagcacata acaagatgca gatttataat
     5281 attcctccac atggtctgaa tgccctgcta tagttactct ttgcagattt aaatctttta
     5341 tctgctggcg aagatctttt tctaattcac cttttcctac aatgataaga tcccaatcat
     5401 ctactttttt ttctacaatt ttccaagcac ttatcatgtc agcaaaattt ttctcttcca
     5461 ctaatcgccc tactgcaaga aatctctttt tatcataatg atattcgtac tcgatattag
     5521 atatacacgg atttggcata gttataacaa aatcttctga taaactatat tcatcaatat
     5581 gtttttgacg atcttcttct gtgagaacca caagcctctt tgcatatttt tttatcaatt
     5641 ttttagcctt gaatctcttc ttttctttca gcatttccat tgtccagtaa ttaaaatgtt
     5701 cccaagaaat caatttgcac tttgttcctt taattgccct tgtagtatac aaagacaaca
     5761 aagtatcaat atcaattact atatcaaatt catttttgca tatatacttg tgcaatttcc
     5821 aaaccggata taaataagtt ctatataatt ttccctccgt tttaggattt aacatataat
     5881 caaccttaat cgtcttatct aacccaaaat aaggctctcc actattccaa aagcttaaaa
     5941 tagtgacatc ataacctaaa tcagacaagc tattggcaat aatactccct actctttcag
     6001 ttcccccaga acgagaaatt acaccactaa tgaaacaaat tttcttcaaa gtacttttct
     6061 cctttataag tgtaaaaatt ttttcagtgc aagtaacctg ttaaattttt tttgtccaat
     6121 tgttgatttt aatctataaa caaatttttg tttaggtgtt ttccaagatg cattatattg
     6181 atgaatgctt attgtattac tagttttata aatttttcca gtatcataat ccttggcagc
     6241 aaaataatcc gtaggataga tatgcaggcc atttattatt tgttcgctgt tatcgcgaac
     6301 caatccaata gattcaagat aatctgtaat ataatacgga ctcggtttca agttcaatgt
     6361 accatcattt tgataaaaac ttaatgaatc gtaaatatcc cttaaacctt taataacaga
     6421 atgtccttct tctgcaccaa aaccaatacc gccattaacc cagatttccc cttcaaatcc
     6481 catataggca tgattttcac gaagtatatc taacgactta attagctcaa catctgtatc
     6541 taaataaaat ccaccatgat tataaataat atcaaatctt gcataatctg gaacaaaacc
     6601 ccatttacgt tctttatatg catcggccat ataacggttc ttatttaaat cataatttga
     6661 ttcattccat tcaataatct cataatcagg gcaatacttt ttccagcttt ctatgcactt
     6721 tctatctttt ttcggaagtg gatttccccc gaaccaacag taatgtatct tcttaggaat
     6781 cataatatct ctccttttgt atttttttca ctataataat gctctttcct tttcacaact
     6841 tcaggcatgg ctaaaatcat ataaatcagt ggccccgttg tttcacccct aagtgttgtg
     6901 ttatacacaa aaaagaatac cgacataatt gcaataactt taacaagact tgcatcttta
     6961 tccttcataa aagatctttt tgcattgaaa aatgtcttta ttataaaaaa taggaatatc
     7021 gaaactccta atattccaac ttctataaat aaccaaatat gatgaaaata ctgataatga
     7081 agattaccaa acgatttata aaactcactg acaaaaaaat tggtaaactc tgcattgcca
     7141 atgcctactc ccattaggac taatctaaaa ttattattaa atatttcatc tactactcta
     7201 gagataccag ttattcgatt taaatcacca acaccatcat atccagaatc tcttgacgca
     7261 tattctaaaa gaccttgaat tgtgaaatta tcagcatagc tttgtccatt atcgttcaat
     7321 gtaataaata ttgttataaa aaaggataat actatcgaca caagtattac gcatgataat
     7381 atcttgatca ctactttaaa atcaactttt aaagtgaata ctattgcaac aaatattata
     7441 aataattcag gaataaaaac tttcaattca gctaatgcag acataaaaag tgctgcacaa
     7501 acacataaaa taaaatggat gaaatttttt tctcccttga aatatccgat tgtaacaaca
     7561 gtaactgtca cacacaaaat taaattcaat ggcatattac aacctgaata attccaaaaa
     7621 actccaccta tcatatctcc tacaattgtt ccagttggat aggtgaccat gaatctttca
     7681 attaaacaaa gtggcagtga aatccagaat aatttttcaa ttatagcgaa tactttatag
     7741 taatctttaa ttgttaaata tgttgcacaa tttatatata ctatgaacat acgagtgtta
     7801 tttcgtatcc cccagataat caatcctata ttttctaaat taataactga gctacaaata
     7861 gaaactagta aaaacaaaac tatcagcatc tcatttttgc tagcatatat tccttttctg
     7921 cgtctaaagc taagtgcatt taataacaca aagatattaa ttatatctcc caaatataaa
     7981 attgctcttg gggcgttaaa agtatataca agaactatgg agattgcaaa aaatgccaac
     8041 gtgaacaatg tccaatctgc tcctgaccat ctttttattg aaatacgcat cgttattcac
     8101 cttctttcgc taaaaattat tctaaaaata cttttgttaa attaacatac cctattattt
     8161 ttgccggtac acctgcaaga attgcaccat tctctagaca atctttgata acaatagctc
     8221 ctgccgcaac aactacattg ttagctattt ttacattacc aataatcttt gcacccacgc
     8281 atacacgtac attatttcca attacaggac acttaggatc gattccatca tttccaatac
     8341 agttattccc atataagtaa caattttttc ctattatggc gttaccatta ataacaattc
     8401 cttgtgtatg gtaaaatctt acaccttcat caaatacatt ttcaccacac tctataccac
     8461 attttcttcc caaactattc attcttctgc aagacacaat atacataatc gcataaatga
     8521 tatttttctt tctctttgaa taataataag atgtaattct cattcgacga gtataccgcc
     8581 aagcgttgta gtccggatgt gatttcatta tttttagtaa ttttgtgtgt tgtcctttag
     8641 attctatata tagattcttt tccatacgaa gaaccgcttt taaatattct ttactgctaa
     8701 tttccattca tatctcctat taattcaatt tatacttaac aattttattc ggatttcttg
     8761 caacaagagc atcattcaat gctactgaat ctacaacgat ggatatgtta tcttcatcgt
     8821 tgattccacc ggatacaata ttacttataa aaatcgtaac attttttcca aaagaaggga
     8881 tgtccgtgat gtataatgcc cattttccga tatttccagt tatttaaacc taacgaattt
     8941 ttacaatagt acaagtatca caatcattaa tatataactg gaatataaat ctccaaaaat
     9001 tcactatagt acagtttttt atgattaaaa tctcctattt ctacccattc cgcttaaata
     9061 tgctaatgtt ttaaccccaa taatggattg gtttagtaaa aaatagttaa atattcgttg
     9121 tttaattgga ttttgtttat atgggtatga gtgaatacag gcaatcaact catcgttcat
     9181 aagtatctta gacaaatagg agtttaaatc aaattcttta ttaaaactag catatctaac
     9241 tgccttttga atacaagtac gacagcgtcc caacaaaagt ctccttgttt tgtttacaaa
     9301 tatctcattt tctaatatat agcttaaatc gccttcaatt tttttaacta attcaatatt
     9361 acaatcgaac tcattatctc taaaattatg tgtcaatgaa ttattattat tacatctata
     9421 ataatagata caatctttaa taaaacttgt tatttttgaa tgttgcaaat atgaaatatg
     9481 gaatatgata tcttcagata tataatccct ttctgacgga aacttgatat tgtgctgttg
     9541 aattatctca gatgaataca gcgcatgcca aactgacatt ggcaatataa aatcgacttt
     9601 ataactcggc tcagtgccaa tcattccaag caacactttt tcaattatag cgttatttgt
     9661 aaatatcgta ctatcatatc ttgctggctt tgaaataata ttattatcat cataatattc
     9721 ataatatcca gcataacatg tgtctgcatt actccttttt ataccattta acattgcttc
     9781 aatataatta gctgcaacaa aatcatcaga atcaataaaa gcaacatatt ttccttttac
     9841 atgttcaagt cctgtatttc ttgccaatcc caagccagca ttatttttat gaataatacg
     9901 aatccttgaa tcctttaatg catagtcttc acatatttta ttagatgaat ccttagatcc
     9961 atcatccaca attataatat ctaggttctt atatgtttga ttacacactg attccaaaca
    10021 acttcctaca tacttttcaa cattatatac aggtatgatt acactaatta gatcactcga
    10081 attcatcctt ctatcctttc actcacgttt tctcaattag tcaatgacgg catcaacgat
    10141 tttcttaaat tctctgaaaa aaatagactc tgatcttgat gatgtgaatg acatactatc
    10201 ttcttctaga aaaattattt cctttaaatt atttattaaa tcaataatat gatcctcgta
    10261 agtatgcttt cccttggaat aatgaaaata tacttttgta ttacacaata ttgcaatttt
    10321 atttcttaat atgattattt cactcattca ttactgccac atatacacaa cttataacca
    10381 ccccctgcaa agtttagggt aagttatcag ataatatctt cctcttcatc atccagaata
    10441 caaaatctat ttatttatag aaatatcatt aatgttttta tataatgtac cgtgcttgta
    10501 ctcttgctct attacaagca ctaaaacact actattcatt tgaattctta cacggataaa
    10561 aatttacatc gtctatttca atattttttc tctctatttt attcacttaa taagttcatt
    10621 acataatcga aacatttttt attttccttg tcatcactcc ttgctccctt tttgatacag
    10681 atttaaaatt ctatcaaaga aatttccatc gttaaatttc gttattgcca aatccttcga
    10741 acaacgtgaa aattttacgt atttatcttt atcattgatt tttagtattg cagatgtcaa
    10801 cgctgatacg tcaccaggtt gaaacaaata tccattttct ccatcacgta ctgctgaaga
    10861 aatatctcct acatctgtag caattacagg cattccataa gaaatcgcct ctagaataga
    10921 tataggcaat ccctcgttat aggacggtaa aatcatcaca tttgatcttc tatagcactc
    10981 ctcctttttt tctcccacaa cccaacctgt aaattcaaaa tacgattgca aattatattc
    11041 ttctatcaat tctttgagcg atatttcttc atcacctgct ccagcaatct caaaaataaa
    11101 ctttttttct ggatattgtt ctgcaatgtt tttaactgct tctaccaaat cgtgtacacc
    11161 ttttcgcttt atcaaaactc ccataaacag aaatcggcac atttttgaat tccactttat
    11221 ggtatattct ggaactacaa tagaattttc tacaacaaca gttttacaat ttggctcaat
    11281 ttctttaatt atcttcttcc atttttctcc aagtacaatc gtggaatcag actctcttaa
    11341 cagcaagcga atctgatttt gtttttttac agaaacacta tcataccatt ttttaaattc
    11401 cgatccatga agatggatga ttacaggaat atttaataat ctaaaccact tattcagcac
    11461 atatttccta ctaaaactcc ctctgtacga catgtgcata tgaataatat taggtttact
    11521 caataaagag atacctataa ttttagcaaa tgcatacata aaatataaag atttaaatat
    11581 tgcatttcca cccttataac tcggtataaa agtcatctcg atattctttt tttcccaatt
    11641 aaaattgagc atttgtgtaa ttatacttgt aattccacct tttaccgagc tgtcattacc
    11701 aatcataagt actctttgca taacgcttta ctccttatat ttatattttt tctattaata
    11761 cctctatcga attaataatc gtttccgtgt tagatacata cttgttaaac atccgaactc
    11821 ttgtttcttt aacggcatct tctaaatttt ctaattcata acaaggatag ataatattca
    11881 tctcatcaaa ttgtctaatt aactgcagtt ggtgatcatc gacatgctca ccatacttag
    11941 ccaatcgagg aacagcaatg acccttttac ctttttttac ggccccaatt atagcacctg
    12001 tacctccatg agtaatcacc atttctgctt tttgcatagt ttcagtaaac tcatccctat
    12061 ttagaaatgc tttataggaa taatttagtg gtttataatc actataacca ctctgtgcaa
    12121 atgtactttc gattattact cctttttcaa ttaaatcatc aatagctttt aacaatctat
    12181 caaattgaaa tttttgtgaa cctaatgtta taaatatcat ttttttctcc tattatttaa
    12241 tatatcccac ccaaataaat agcattagga taaaattgta gcatagtttc ccactgaaca
    12301 taaaattgat ctgcaaaatg atacatcaat tttcctgtct gagtagggct ggttactttt
    12361 gcaaacgatt caatataaat cagttttttt cccatcattt ttgttattaa gcagataggg
    12421 atcatagcta aaacacctgt acaaatcacg agatccggtt tttcctttat atatataata
    12481 attgatttga ataaattaat aagtatagta cacaaaaaaa acttttcttt tctatttact
    12541 tgtctcatgt agtacgtttt ttcgcctttt gactcagctg aatattctgt ctgttctgtt
    12601 ataacaaaac tctcatactt ctccatcagt ggttttaaca tcattaactg ttcataatgc
    12661 cccccagagg aagccgcaaa acatatcttt ttgttcatat taacctctct atcagtcacg
    12721 ctgaaaaata tctctagtgt aaactttttc tttaatatca tccaagcagg tatcatatcg
    12781 attggcaata atagaatcac acatcgcctt aaactgctct aaatcgttga taaccttact
    12841 tccgaaaaaa gtctctccat ctttcagtgc aggctcataa atcaccacag tcgcaccttt
    12901 agcttttacg cgcttcataa ctccctggat tgaactctga cgaaaattat cactgttgct
    12961 cttcatggtc agccggtata taccgattaa aactggattt tccctgttga catcatactg
    13021 attatattca gcgtagttgt aatagcccgc catctgaaga acacgatctg cgatgaaatc
    13081 cttacgggta cgattagatt caacgatagc ctcaatcaaa tttccaggaa catctgcata
    13141 gtttgccaac aactgcttgg tatcttttgg caagcaataa cctccatatc caaaggatgg
    13201 attgttgtag tgagttccaa tacgaggatc gagacaaaca ccattgatta tctgctgagt
    13261 attcagcccc ttcatttcag cataagtgtc taattcattg aaatagctga ctcgcagtgc
    13321 taaataggta tttgcaaaca gctttactgc ttcggcttca gtgaatccca taaaaagagt
    13381 atccacgttc tccttaattg cacttttctg cagaagtgtt gcaaaaacat gagcagcatt
    13441 taacaagcgc tcatcagtca tatcagtacc aacaataata cgagatggat acagattatc
    13501 atataaagcc ttgctctcgc gcagaaactc tggactaaaa ataatgttct tactccccgt
    13561 tgtctcacgg actgattcag tgtagccaac aggaattgta gacttgatga ccatgatggt
    13621 atcaggattc acgtccatca caacctcaat aactgactca acagcagaag tatcgaaatg
    13681 ctgagtacga ctgtcatagt tagtcggtgt agcaataaca acgaaatctg cggatttata
    13741 agcgctcctt gcatccaaag tagcagttaa gtcaagttct ttttctgtaa gatacttttc
    13801 aatatattca tcctgaattg gagacttccg tttattaatc agttcaatct tttcagggat
    13861 aatgtctacc gcggttacct ggtgatgctg cgccaatagt gtggcgatac tcaaaccaac
    13921 ataaccggtg ccggctactg cgatgttgta ctttttcttc acaatatctc ctctttcctc
    13981 tcttaagtat ggagaatgtt actcctacgg ctattcatca tgtcaaaata acacagctta
    14041 gaatgttgat aaaataattt tccagaatgt gataaaatct ctttcattta taaaccacac
    14101 atctaatttt atctattctc cacaagacat gtagagtatt ctttaataac aagatacgac
    14161 cttactaaat acttcaaaaa attatcatat ttaattcata aatataaatc ttcattttaa
    14221 atgtatgccc aaaaatttat ctgtaatgcg tcatcaaaat ctagattcca aatctttatc
    14281 aatttttatc cactcattct accactttag taatattttc tatttataac actttcgtcc
    14341 tacattgatc cccccctctg aagtacagtt tttactgtct taaataaaat tttaaaatct
    14401 aaccccatac tccaattttt tatatattcc gtgtcaagtt ttgctacttc ttcaaaatca
    14461 gtaatatcac ttctaccact tacctgccac attccagtaa ttcctggctt gatagcaatt
    14521 cttgcacgat gatgataatc atattcttca tactctgatt taaggcatgg tcgaaatcct
    14581 ataaggctca tctttcctgt tagaacgttg aaaaattgag ggaattcatc taaagacgtg
    14641 gatctaataa attgaccgat tcctgtcttt tttgttccat ctggaagtat tttatttccg
    14701 ataattcttg gatcaaactc catcttaaac ataagattat tgctcatctt attttctttc
    14761 attaattcta cttttctttc ttctgcatcc atatacatac ttctaaactt atacatcttg
    14821 aacggtttac cattctgacc tatacgttct tgtgcaaaga aaattgggcc tggtgaatta
    14881 atataaataa gtggagcaat aaagataaaa ataattcccg ttgcaataca tccaacaata
    14941 cctgcaagaa tatcaattgt tcgttttata aatgcctgtt gagttgtcat aacattgata
    15001 cttgttgtaa gtactgtata ttctcctata cgaccaatag attgttttcc caaagcacta
    15061 tctgatactt ttgcaagatt caaatgtaca gtaaggccca tttcagagca tcgttcaata
    15121 aattctttca tacacgaagt acttttattc aaaataataa agacttcatc tacccatccc
    15181 tgacataagt aatccgctgc atttttggaa tcagaaacaa ctgtcactcc ctcaacatct
    15241 tcaccaatca tgcttttatc tatgataatg acaccattta ttttatacat tttatagtta
    15301 tgctctttca cattacgaat aactacttca gcaatactac tagatgtaac tataataagt
    15361 gatttgttcc cctcattttt cattttatgt ttcaagtaat gtttccataa gaggcgagtt
    15421 atatatgtaa ttacaacgta taaacctccc atcaagaaaa gaacgactct agaataatca
    15481 tttccaccct gaacactaat gagatacaaa cttcctaaca gcaccaacat aatcgcttgc
    15541 tttacagaag aagcaaattc tatatagtac cctcttttta atacacctct atatgcttca
    15601 aacatgaaaa taactaaaag atctgccagt tcaatgaaga ctgccatgtt ttgatacatt
    15661 ggaatcacat aaggattcca atctacctgg cgtaagacat acgatagata aaaagcaagc
    15721 tggatacaca ataaatctaa aataataaaa tcaatatgtt taacccatcc ccttgaactt
    15781 ttcttgtaca ttccttttta ctcccctctt tttaataaaa taaattgtat tacttgtttt
    15841 ctctcctaaa tatctttctg aaggattatt gactcgacaa attggcttgt ggatattctt
    15901 atatatagaa catccgtaag ccaacttaaa actccttaac aaaatttttt tactcatatt
    15961 gtagatcaaa acaagtatcc aagaaatcat attttatttc ttttttctgc ttactcaaca
    16021 acagctaaaa gaaaaatcat cataaacaaa ttcaactaag ccaacgatcc ccttgtgaaa
    16081 tcaagttttt tcttgattta cgaataaaga gctaaaataa accaaacttc ttctttttta
    16141 cctcttcata gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt
    16201 tcatctgtac tactttttcc ttaccaaagt cctttgcaat ctgctcatag cactctttta
    16261 agtaaaaggt gcgcttagag accccatggg catcagaagc agccatctgc acgagattat
    16321 gtttgaccat cgttttggct gttttctgga tgtctttgcc aaatacccca acataacttg
    16381 gcgcagtgag ttgggccaaa catcccatat ctaggaacgg aagcaaatga tttgggtctt
    16441 cgcgaaaatg cacgttgcgt tctggatgga cgattactgg tgtctttcct agttctaaca
    16501 actcaaaaaa aagccgttct gcatataacg gcacttccag tgtcggaaat tcgatcagaa
    16561 gatatgtatc atctaaatct gtaaataata tttcatctcg gtggatgtct tcgatgagcg
    16621 ttccggtaat acgtacttct tgtccttcca ataacgtcaa aggcaactgt cttttctcta
    16681 attcggcttg taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc
    16741 cattattgtg gtgtggtgtg cataaaatat gcgtgatgcc ttgctgaatc gctttttcag
    16801 ccattgcaat acttgcttct aagttttctg ccccgtcatc gattcctggt aggatatggc
    16861 aatgtagatc gatcatttct cttgtctcct ctcttcttat tccttaattt ccgtagtaat
    16921 aaccagcatc tttgctatgt tctgctccgt tgtacacaac acctaagact cgtgcttgta
    16981 ccatctccag cagttctttt gctttagtca aggattcttt acgtgacata ttttcacgta
    17041 cgaccaataa agtgccatcc gtttttaaag acatgatctg tgcatctgtt acggctacta
    17101 ctggtggcat atcgaatatc accacgtcaa ataactgtct tgcttcggat aggatctgat
    17161 ccattcttgg cgagcttaac aattctgatg ggttgggtgg cttaggtcca ctaggcaaaa
    17221 tcgacaagtt ctcgactggc gttcgttgga tcacatctgc tacacttcct gatgaactaa
    17281 gtgctgtact taatccactg gcattgttca gctggaatgt cttatagacg acgggtttac
    17341 gtaaatctgc atcgactagt agaactcgtt gacctgattt agcaaaaacg actgcaatgt
    17401 ttgctgcagt ggtggatttc ccttctccag gacctgatga agtcacgaca atcgttttga
    17461 tttgctgacc agctgcggag gcaaactgga tattcgtccg gatcgtacga tattgttcgg
    17521 cgattggtga agatgggttt gttaatgtga tcaaactgac tgcatgagtt tgtgctgctt
    17581 tttgtttctg tgttcgtgcc atttttcttc ctcctagact cttgagcggc ttctgcgtga
    17641 tggggctgtt ttatcgtttg tagcttttgg tcgtgcagga gctgttcctt ttttacggat
    17701 accagcgttc aattctttcg ctgacatttc tggaactgtt cctaagattg ggaatcctaa
    17761 tgtatctgtc acatattttt catctttcac tgtccgatcg agtaattcca ataagaatgc
    17821 cagacctaca cctaccatca ttcctaacat taagccagtc attaaattca atttattatt
    17881 tggcgaaaca ggtgtcgtat tggcaactgc acctgaaatg atcgagattt tatcaacatt
    17941 catcacatct tttgcgttct cttggaaaac ttgtgaagtt gtgttagcga tctgttgagc
    18001 agccactgca ttcgtactta ttgcctgaat cgagaacatt tgtgaatttt ctgcctgatt
    18061 aactgagatg gcatctttga tttgttcagc agtcattttc acattgtctt ctgtttctaa
    18121 acgatctttg acttcattga gcactaaatc actgacgatc atatctttat acgtattgat
    18181 catttgcagg ttcgtattga catcattgac atttgcagtg tctgattgtg gcagtgtcac
    18241 gatcaattgt gcttgtgaac tgtattttgg tgtcaagatg aaaaatgtta cgattcctga
    18301 gatggccaag ccagcaaaca ttgagatgat gattattacc aagtgtttgc gtaatgtttc
    18361 aaaaatttct ttcaagctga ttgtctcttc cattttttct ccactttcct atttattctc
    18421 tagattcatt tgatctttta attctttttt cacacgatca agttcttgat cactgacttt
    18481 ttgataggag atattatctt gcatgaagcc ttctccttgc agctgatctt gcttaatcgt
    18541 accaaatgcc tcccgataat ctaaagcaat ttttttcatt tcatcaaagt tcatgtctgt
    18601 tttcatattc gactctagag cattcaaaac ggattgatag ttgctgacac cgtttagact
    18661 caatactttt ttcgctacgc cttctacgat ctttctttgg cgcccttgtc taccgtaatc
    18721 accatttggg tcttcataac gcatacgaga ataagataat gcctgatccc cgttcaatgt
    18781 aattttaccg attggaaagt catagccatc ttgtgagaaa gtgaggtcat tattgacttc
    18841 gataccacca actgcatcaa cgagttcctt tagtcctttc atattgatag agacatagtg
    18901 atcgattggg atgtctacat atttttgtac ggtatccatc gccatggcag ctccgccgaa
    18961 tgcgtaagcg tggttgatct tgtcttttgt gtcacgacct acgatgtcga catacgtatc
    19021 tcgaggaatg ctgacgatcg ttgtctgttt gtcttcagga ctgactgtgg caaccatcat
    19081 cgtatctgat cttccttgat cgacccgacc taaatctcca gtatcaatcc ccatcaatag
    19141 aacagagaaa gattcttgtt tgtccagatc aactggtttc gttcgttctc cttgggttcg
    19201 ttccactgat tcgtaagttt tctcaataga atgtgagaga tccagatata attttgctcc
    19261 tactcctaca attgctaata ctaatacgat aagaactgct aaaataatca aaaatatttt
    19321 tttccctctt gattttcttc ttcgtcttgc catagtttcc tccgtttgct aaccttgctt
    19381 gaatcaacgt tttaactgtc aatagcttat attgctatag cccatttgct gagcaacagt
    19441 ttgtgctttt gttgcgtatg cggctcttat tttttcattc cggatctgct ctatttgact
    19501 gagcgccgtc aaatattgat cgtaagtagc ggtagctgtt acttgaccgt ctttcagcat
    19561 cgtatcgaat agctgatcta gttgcgtgac ttgtgcaatt tgggtatcag cgaatcctag
    19621 atattgcata acgactgttt tccaagcact atccttaaaa aagctcatat tttcacgtac
    19681 atgggcgaca tctgcacttg ccaacttttc tttgatgatg acatcatcca cagcttgctg
    19741 ccagtttgat acgtttttag taaataattt attgacagcc gtctggatct tcagttttga
    19801 ttctgcatcc tctaactgcg ttaagactgc tttcttttct tcttggatcg cagcagcttc
    19861 tttaggtaat tctgattcct tgatgtcata atcatctgcc gaaagtttga tagaagatag
    19921 tttatgtgac aaatttgaaa ctgtttcttc tgttatttca ggatttagga aaattttttc
    19981 ttttgtactg tacagcttat ctacttcttt tgataaagag gtcacggtgt ctttttgatt
    20041 ggtgatggca gattctgcgt aattgatccg ttgatgatat tgccgctgat tattgagatg
    20101 gtatccaaac aagcaaatca caatagcgcc tgtgcctacc gccacagtag ccaataactt
    20161 gacgaacggc ttttccatag attcactcct aaatattgat gatagataag taaagatgtg
    20221 attcattcac atcagaatga gcgcttttta ttttaaaagc ataattaaac taatatattc
    20281 atagaaatat ttataaacag gttttcccta tataatcata ccacatacag tttttttgac
    20341 tagggaaatt cctaatttaa aagtaaataa aacagtaaca agattataat taatcgtttt
    20401 catttttatt tcctcacttt tcatgagcgt tttgaaaatt cgaacaaaga ataaaataac
    20461 aaaaattatt aaaatagaat taataacagc tatttataac aaaaaaaaca gagacacagc
    20521 acgtttcgtg catgctctct gtttttcaaa caaaagacta ttttgtgatg atttgatcca
    20581 agcttgctaa tgacaaagcc atggcagcta tttgacttag ttgtgttagt cggttcttac
    20641 gtactgctgg ttcatcagcc atgaccatcg tttgatcaaa ataattttcg atcagtggac
    20701 gaagagcgac aagctggtcg tagttttcgt ggatcgtttg gtcagcaaaa cttgctttca
    20761 ttgcttctac tgctttgtgt aattctttct ctgcgtcgtt ttcgaacagc tcagggtcta
    20821 cttctgattg tttttcaagc tgcgcttttt tcgctaagtt cacgacacgt gtcaaagctt
    20881 ccattgaagg tttgaagtct tcatctgcaa gatgttgttt gaacaattgt gcagctgcaa
    20941 atacttttgt cagatctttt tgttccgcat tcaaaacagc atcgatgaca tcatgacgaa
    21001 tattcttcgt tgtcaataat tggcgcagac ggcctttgat aaagtcgatc acttgttgtt
    21061 gcccttctga taaaccaatg ccgaaacgat ccgtatcttt actgataaca tcgctaatcg
    21121 tttcttgcag aacagacaaa ggaaaggccc attttttcga ttcgatgatc cgaacgacac
    21181 cgtatgcttg gcgacgtaag gcataaggat cgtttgaccc gcttggaatc atcccaactg
    21241 caaagaaaga aaagatgcta tctaatttat ctgcaatcgc taaaacagaa cctactgtag
    21301 actgaggtag ctctccttca ctggatatag gcatgtaatg ctcacgaatc gctgtcgcta
    21361 cagcaggttt ctcgcctttc agaagagcat atttttcgcc catgatccct tgtagttcag
    21421 gaaattcccc taccatgttg gttactagat caaatttata gatttcagca gctcgttgca
    21481 aatccatcaa ttcttcctca gatagtccta cttgttcgcc aatgatacgg gcaatgactt
    21541 gtacccgttg cattttctca tagatactac cgattttttc atggaaagta acagttttta
    21601 gtttttcaac gtattggtcg attgaagctt tcttgtcttc attataaaag aattccgcat
    21661 cttctaaacg agccgtcaat actttttgat tgcctcgaac cacatcttcc aattttaccc
    21721 gatcaccatt acgagcagaa ataaaatgag gaagcagcat accttgatca ttccgtacct
    21781 cgaaataacg ttgatgttct ttcatagaag tgactagtac ttcttcagga acagaaagat
    21841 atttttcttc gaagtcgcca gaaaagacag ttggatattc gactaaattg ttgacttctt
    21901 ctagtaaatc ttcgtctaga tcaataaccc agtgattttt ttctgctaat tcgtttgctt
    21961 gtgtaacgat catttcttgt cttttttgcg gagacgcaat gacgaattgt tcattcaatt
    22021 tttcttcata ttcttttgca tgcgcaaatg tcacatcttc gcctaagaaa cgatgacctc
    22081 gagaggctct gcctgttttg acatccaaga tttcgaatgg gattacttcg tcatctaaca
    22141 atgccacgat ccagtgaata gggcggatat attcaaaatc gtattctgcc caatgcatcg
    22201 ttacagggaa agtcaaactt ttgatcaccc ctgctaagcc tgtcaatact tcttttgctt
    22261 ccttaccatg agtgtatttc gttacataga catattccac accttttaat tctctaaaag
    22321 tgatagcgtc tgtcgtcaga ccttgtccgc ggacaaatcc ttccgctgct ttcgtccagt
    22381 ttccatctgc gtccaaagca atttttttgg ctggtccttt gacttcttct tcactgtccg
    22441 cttgtcgttc tggaatattt gttactttga ttgctaaacg gcgcggtgtg gaaaatgttt
    22501 cgatcgtatc ataagtcaat tggttttcat ctaaaaattt tgctgttttt tcttctaatt
    22561 gtttcatgct tggtgtgaca acatgggcag gcatttcttc cagcccgatt tcaagtaata
    22621 agtcttttgc catcttattc agcctccttc acggtttctg gatttgctgt gtttttattc
    22681 aacaaaggga atcctaattt ttcgcgttct gccacaaaga ttttggctac agcacgagcc
    22741 atgttgcgga tgcgagaaag ataaccggca cgctctgtta cggatactgc accgcgggcg
    22801 tctaataagt tgaatgtatg gctacatttc aagatataat catacgccgg atgaacaaga
    22861 ttttcatcga tacagcgttt agcttctttt tcaaaacgat caaagttgct tagtagcaag
    22921 tcttggtcgc ttacttcaaa agaatatttg gaatgttcat attctggttg tttgaagatc
    22981 tcgccatatt tcacgccatc agcccattct aaatcataga cactttcaac ttcttggata
    23041 taagaagcaa gacgttctaa tccataagtg atctcagaag ttactggttt acaaggcagt
    23101 ccaccaactt gctggaagta cgtgaattgt gtgatttcca ttccgtcaag ccatacttcc
    23161 caacccacac cggcacagcc catggatggg ttctcccagt tgtcttcaac aaaacggatg
    23221 tcgtgttcta atggatcgat tcctaaaagg cgcaagcttt ctaaataaag ctcttgaata
    23281 ttctcaggtg aaggtttcat caccacttgg aattgatgat gctgatacaa acggtttggg
    23341 ttttcaccat aacgtccatc agctggtcgg cgagatggct ctacgtaagc agcattccat
    23401 ggttctggtc cgattgcccg taaaaaggta tatgggctca tcgtacctgc tcctttttct
    23461 gtgtcataag cttgcatcag catgcagccg tttgatgacc aaaatttttg taatgttaaa
    23521 atcatatctt ggacggtcaa ttttttactc atctgttttg cccctttcaa ttttaaagcg
    23581 ttgctgtcaa ataagaatac aggaaagaaa acgacaaaaa atccctatgt ctgattacag
    23641 acatagggac gaataattcg cggttccacc ctacttccga ataaagattc ggcagcttca
    23701 tttatcgtac tcgcaagtgc ctcttcaaaa atcgtttggg tccggctccc actctcccga
    23761 actcgctaaa ccacgtgttt tttactgatc ttggtcaatg tacgtattca ttttgcagtt
    23821 ttcttgtttc tataatagat cctatcactg aacgatctat ttaatctatg gttaataata
    23881 gacggaactc cctgtgtttg tcaaatggtt ttgatttttt gttgtatgtt ttatttacta
    23941 ttcttctttt tcaggtgtct ctttttcttt ttcagacatg tctttctctg acgtctttaa
    24001 tacgtgtgcc caagacttca tttgattgat gaactttttg cttttcaaat ggataccgac
    24061 atattcatca tacagctggt cgatgagttc acggattgct tgtttggttt cttctttcag
    24121 atggattcca ctaattttat cataagaaat agctgaaaac atccgaacga aataaacagc
    24181 tcgaggatct gcatgataac ggtgatcgtc catcgaccaa tgtctttcgc atatcacacc
    24241 accatatttg gaagaatagt caaattttcc ttttgtttcc ccgcatacga cgcagtgtgt
    24301 ccagattggt gcaattccga agcgttgcag tatttggact tcaaaaatat tcgtgatgat
    24361 ttctgcatcg tctccttggt ccatccgttg cagtgcttgt tgcgtaaact ggaacaaatg
    24421 cgggtcgtac tgatgatctt cgattgccgc atctactaga ttcaataaat atgtgccata
    24481 gccgctcaaa aagatgtctt cttggatgtg tcgaaacgca tggacatctt tgacactgct
    24541 taaaaatgac aaaccttcac ttcgaaaatt cccgatataa actgcttcag taaaagggag
    24601 caaagccgga gctaagggct gattttgccg atggatctct ttgatataaa acatcatttt
    24661 gccagaagat tctgtaaaga ttttgactaa tttatctttt tctttgtaat tacggctaga
    24721 taaaatcaag ccttttgatt ctgcaagctg gctcatattc tccctcctaa aaaataaatc
    24781 tggaaaagca gattctgccg atccagatca tttatgttgc gatcttccgc agcttttctc
    24841 aacacgcgga tttttattca gtttatttct atacctaatt tacaagaagc tcagaatatc
    24901 agtattcgtc ttttcggtag ccgaagtctt gcagatagac ttttttgtct cgccagtctt
    24961 tttgaacttt gacccaaagt tctagaaaga ctttgtctcc taaaagattt tcgatatctt
    25021 ttcttgcttt cgttcctact tgcttcagca tttttccgcc tttgccgata atgatccctt
    25081 tttggctatc tctttcgaca ataatcgtag cctggatatg gattttatca ttctcgtttc
    25141 gcttcatcga atcaacaacg actgcgacag aatgaggcac ttcgtctcgt gttaaaaaca
    25201 agactttctc acggatcaat tcagaaacga tgaagtattc aggatgatca gtcacttgat
    25261 catctggaaa atattgtggg ccctctggca tttcactgac taatacatcc atcaaacgtt
    25321 cgacgttgtt tccttctgta gcagagattg gaatcacttg tgcaaaaggc atctgcgttg
    25381 aataatcttc gatgattccc aacaactcgt ctggatggat tttgtcgatt ttattgataa
    25441 tcagataaac aggagaatgc acgtttttta gacgttcaat aataaaatcg tctccccgac
    25501 cgcgtttttg atcagcacta atcataaata agaccgcgtc cacttctttc aacgcactgt
    25561 aagctgcttc taccataaaa tctcctaaac gatgctttgg tttatggatt cctggtgtat
    25621 caataaaaat caactgagct tctggtgtag tgtatactcc ttggatttta tttctagttg
    25681 tctgtgcctt gtcactcatg atggcaattt tttgacccac gattcgattc aataatgtgg
    25741 atttccctac atttgggcgg ccgacgattg cgacaaaccc tgatttatgt tctggcatat
    25801 atgttctcct ttttaattaa acaacaaatg atatatttta gggacaaata aaatcaaccc
    25861 aacgatgacg gtaaaacaag cggtcactaa aactgctcca gctgccatat ctttgatttt
    25921 tttcccaatc ggatgaaaat gaaaatccgt aaacatgtcc acgacatttt caaaaacagt
    25981 attgatgatc tctactatcc atacgagaaa aacagctaaa agcagccata accattctat
    26041 ccgatcaagt tggaaaatca cgcccataaa caaagcgagg attccgaacg caacatgttt
    26101 cctcatgttg cgttcttcct caaaaacagt tttgactcct tggacggcaa attccacgga
    26161 catcaggaaa tgtttgtttt tctctacgtt tttatctttt aagtccatag gcatctaaga
    26221 tctctttctg taaaccaaac atttctttct catcctctgg tgtcatatgg tcatacccgt
    26281 tgatatgcaa gaatccatga accgctaaaa agccaagttc ccgatcatac gaatggccgt
    26341 aagcttctgc ttgctctgca gcacgttcag tagagatcat gatgtctccc agtacacgag
    26401 gcaatggatt ctctccatct tcaaaaatca ctgggatttc gtcttcgccc tcttcttcca
    26461 aggcaaaact gatgacgtct gtcggtgcat cttttccacg gtaatcacga ttgattactt
    26521 ggattgctgc attgtccatg aaagtaacag acatttctgt ttcttctggc aactctaaat
    26581 atgatgctgc aaattgcagc aagtcgtcga tttctttcat tttctcttct gagacttggt
    26641 ttgtttcatc catgaaggta atatccatta tacatcgctt ctttctattc ttcttgctat
    26701 tcttcttgtt cttcttttat cttctcaact tccgatttca ttttaggata tttgatccga
    26761 gaatggaagg tactgcttaa accgctgatc aatgattttt ctactttacg gatttctttt
    26821 aacgtcaatc cactgtcgtc caattgtcca tcggaaatac gctcttcaat aagattatgg
    26881 acaaaacttt cgattttttc gctcgttgga tggtccattg cccgtactgc cgcttcacaa
    26941 ctgtcagcta tattgacgat tcctgcttca cggctttgag gttttggtcc aggataacgg
    27001 aattgctctt ccgtaacttc cgggttgcgt tcctttgcct taacgtagaa ataacgcatc
    27061 agcgtggttc catgatgctg tctacaaata tcgatcacca tttgcggcat attataatct
    27121 tccaatattt tggcaccatc tgtcacatgt ccaaagataa tatgtttact gtcttctggc
    27181 aataagaaat tgtgcggatt ttccgctcct gaaggcaagt tctcaacgaa aaagctggcg
    27241 tgtttgatct tgccgatatc atgataatag caagctactc gagttagtaa agaacgtcca
    27301 ccgatttctg ctacagcatt agcacttaga ttggctacca tcatgctatg gtgatacgta
    27361 cctggtgctt cttccagcaa ctgtttcaat aaaggatgat tgggattgct gagttcattt
    27421 aatacgatca cactatcatc attgaccatc aattcaatat aggggtgcag acctatcgtc
    27481 agcaagaatg aaaacagtgc acctgtgaat ccgcagacta gcgttaacca agtcgttgca
    27541 tccccaaagc tcattccttg gtagataatc aaaatgacat ccatcatcac aggaaaaata
    27601 atgacccaca tagcagcgga taacccttgt tctgagatcc gtttgcgtct gacgatcgtt
    27661 gccatgagac cagaaaatac ataggacatc aaaataactg tcagaaagtt cgtgccaatc
    27721 gaatcataaa aaatgaaaag tgcggatact gcttgaaaaa taccagccat gatccctgct
    27781 cttcgattca agaaaaagct taaaacaagt ggagcaaaag ccgcggggta aaacagcgga
    27841 atataagcag cttgttctgt ttggaagagt tggaaaaatt tcattagtac gacgcttact
    27901 gacattgccg tcacgtagaa aagtacgtat tttgttcttt ctcctgcatt ttggaattga
    27961 agtgaattat aaatcagtac accgatttga agcaaaacag ctaaaaccat ggcaatgagt
    28021 gggaaaatag aagtcgtttg attcgtcaat cctagtaatt ccaatttttt catcgctgaa
    28081 gcatcaattt gatttccttc gcgaacaata atttctcctt ggaagatcat cactggttgt
    28141 acagcttctc gtgcagattg ttttaattct tctgtctttt tctcattcaa tacatcatta
    28201 actacgatgc cttgatccac taagtagcga atcatttgtt gctgctctgt tgtgacattc
    28261 aaatattgaa tctgatcttc tgcttcttgt ttaaaagctt ccaattcgct ttcacgaact
    28321 tgtttactca tctgttcgtc aatgagcttc aaactttcat ccctaactgt gtgaatttcc
    28381 gtttcagtca tttcaaatat cgtcgaataa aaattgttcg gcagtttttg gtaaaacgca
    28441 acgttttctg cattcacgtt ttcaaaattt ttcttcagtg tagcaatccg ctcttctgta
    28501 gtaggtttcg ggatattttc atcttccttc gccttatcta ccttgccatt ataagatttg
    28561 ttgatggtat cattcgtctt atcgatcaat tcgaataatt gcttgatccg attgttctgg
    28621 tcatctgcca gatctttttg ataagtatat tctggagtca ctgcttctgc tgccagtttt
    28681 cttctttgtt cggtttcttc cgtgttctca atcgttttat tcgcacggat actctcttct
    28741 gctacttggc cttctctgaa atcaatggcc ttttgtttga cactactaaa tgtaacgccg
    28801 cagacaatga taaaaaacaa gaacagaagg aaaggcaatg ctgcctttcc gagtttttct
    28861 tgtagtttct gcagtgtttt attcaacatg tgcttatcct cctaagcaaa gcttattctt
    28921 gatgaagatc cgccttttca taagctttga tgatttcggc aactacaggg tgccgaacaa
    28981 cgtcacttgc ttcaaaatta acaaaatcga tttttttgat ttgctttaat gttcgttctg
    29041 catgaacaag accacttgtc gtcccacgag gcaagtctat ctgacttgta tccccattga
    29101 caatcatttt tgattgataa ccgagacggg tcaagaacat tttcatctga gcgactgtcg
    29161 tgttttgtgc ttcgtccaag ataacgaatg catcatccaa tgtccgcccc cgcatgtaag
    29221 ctaaaggtgc gatttcgatc acgcctcgtt ccatcaatcg gttcgtatga tccaatccaa
    29281 aaatttggta taaagcatca taaacaggcc gcagataagg atccactttt tctttcagat
    29341 ccccgggtag aaagcctagg ttttcccctg cctccacagc gggccgcgtc aaaatgattt
    29401 tttgcacttc gccttttttt agggcagcaa ttgctaatac tacggcaaga aacgttttcc
    29461 ctgttccggc tggccctaca ccaaatacga tgtcatgttt ggctaccgat tcaacgtatt
    29521 tcttttgacc gctgtttttt acccgtatag gttttccatt acggtctttg acgatctctt
    29581 cctcatacat ctcaacaaaa taatctaatg tacctttttg ccccattttc aatgccgtca
    29641 caacatctgg cgtacttacg tggattcctc gtttgatcaa ttcctgtaat gtccgaatga
    29701 ctgaggcagc caaggaaatc tgggattgct caccaatgat ctgaatgatt tctccacgtg
    29761 tatggatggt tgtttccgtt gtttcctcga tcagttttat atgcttgtcg tgtgcaccta
    29821 aaagcatgct gacatcatca gcagctgtca atctaatctc taaagaacta gactcttccg
    29881 tcaaaaatag acatcccctt tttttcgatt cattctttcc tattttacca tactcagaag
    29941 aaactatata gcaaataaga aaaggttgta aaagagtcgc ttaaccatac gtaccaagaa
    30001 acgttaaaaa atagccgttt ccattcgcta aaggtctcgt tttgataaaa agaagctgag
    30061 aatgtaagtt atatgaaagt ggagaacaaa atatttcgtt tcattcaaca agtattctct
    30121 aggtattttt cctgtttcaa aaaaagaaaa caaaatagtt aaaatattct tgcatttcaa
    30181 aaaaaacagg tgtattatta cgtcaacaaa taaacataca gcaaagcgtc gaggaaaaca
    30241 gtaggctatt caacgattta ttcccagtga gtcatgtaag tgagaaatga caataaatcg
    30301 aatagacgaa catcatttcc gagtcaatgt cgaaaacgta gatcattgtg gctgcctcca
    30361 ttatcaggct agcggataac tttatcaaaa agcgtccgtg aatgaagaag cttttttaag
    30421 cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt cccaagtgga aaagggcttt
    30481 tttttatttt aaggtggtgg ttttcatgga atctgatatt agtggcatta ctaattgctg
    30541 caacgtttat atcgtcaatc aaaatgataa ttattggagg aaaaatttat ggaagaaaca
    30601 aaaacttatt catggaaaca actattgatg gtcagttcac ttatcttcgg gatgttcttc
    30661 gggtcaggta atctaatctt tcctgtccac ttaggtcaaa tggctggcgc aaactgggtc
    30721 agtgctggcg taggatttgc tatctcaggt gctcttttcc cattactagc tatcttagct
    30781 gtagtagtga caaaaagtga tggtctgtat gacttagcta aacctgtcgg aaaatggtat
    30841 gctgccttgt tcttaatcct tgttcatttg acgatcggac catttttcgg tacaccacgg
    30901 acagctgcta ctgcttttga aatggctgct aaaccatttt tgcctgaaaa atataattca
    30961 ttaggtatgt ttttattctc tgctcttttc tttttacttg cttatttcct tactgtccat
    31021 ccaacacggt tggtcaaata cgtcggaaag tatctaaact ccttgtttct tgcattatta
    31081 gcaatcattt ttgtcgtttc tttattccat ccaatgggaa atctaaatca atctgctgca
    31141 gatacttatc aaacaaacgc tttaacaaat ggtgtcctag aaggttataa cacggttgat
    31201 gcagtagctt tgcttgcctt aagtgtcact tttgtccatg cagtccgtga ccttggtttc
    31261 aaagataaaa aagtcacaga attaacggca aaagctggta gcctgagcgt tgcgctagaa
    31321 gtcatgatct attttggact tgttcttctc ggtgcgatga gtttgaataa gatgtcttta
    31381 tcagaaaatg gcggaactgc actttctcag atcactaatt tttatttagg taacttcggc
    31441 gctagcttct taggagtgat ggtcacatta ggtgtcttca ctaccgctat gggactcgtt
    31501 gtttcttttg cgcaagattt ccataaactg ttccctaaag tcagttatat gacatggctg
    31561 cggttaacga ctttcgtctc ttttgtcgtt gcaaatgctg gtttagacaa tatcatccaa
    31621 tggtctttac cagtattgat gcttttgtat ccattgtcgc ttgcgttgat cttgctttcc
    31681 ttaacagcaa aatttttcca aaagacacca tttgtctatc aagtaacgat gttgtttgct
    31741 gctgttcctg ccgtattgga tatgctggca aattcgcctg ctttagtgag tcaacaaaga
    31801 gttgtagcaa gcatgctcga attttatcat catcacgttc cttttgctgc attaggactt
    31861 ggctggatgg tcccaacgtt acttggttac gctggcagcc tactgtttta ttacgcctat
    31921 cgcctatcag ggtataaaca agaagcaaat gaactaccag aagaataacc aaatcaaaca
    31981 caatttaaca taagaaatat taaacaggaa aaaaccagct agatgaaaga atcctattct
    32041 ttcgtctagc tattttttag ttctcttttt tacgcgcaca aaaaaactgc ggacaatgat
    32101 tgtccgcagt ttaaatgata aaattaagat tgtaatagtt ctttcacaat ggcatttact
    32161 tggtttccat ctgcttttcc tttgacttta ggcatgatcg cacccatgac tttgccaaat
    32221 tctttcattg atgaagcacc agtttgtgtg attgcttctt gaacaagttg tcgaatttct
    32281 tcgtcggaaa gttgttccgg catgtatttt tcgactatca caatttcact ttttactttt
    32341 tcagctaaat cgtcacgtcc tgcttcttca aactcatgca aagaatcacg tcgctgtttc
    32401 atttcgcgag acaacaccgt taattcttct tcttctgtca agtcgtgacc ttctttaatc
    32461 tgctcgtttt gtatagatga cttgatcatt cggatgactt gtaaagattc cttatctttc
    32521 gctttcatcg ctgttttcat gtcatcgttt aatctactta gtagtgacac actaccaact
    32581 ccaattcatc acagaactag aattttttgc gttttctagc tgcttcagat tttttcttgc
    32641 gtcttacact tggtttttcg tagaattcac gtttacgaga ttcttgtaaa gtacccgctt
    32701 ttgacacgga acgtttgaag cgacgaagag catcgtcaag tgattcgttt ttgcgaacga
    32761 ctgtttttga catgttaatt ccctccctcc gagcttaaaa agtaaccgta attgttattg
    32821 aaatatatct caaaaaacaa gactgtcctg taaatattat atctaatgct gttttgaccg
    32881 tcaaggaaat cttgcttttt tttaaaatta tcaaatgtta ttttatttaa atccttattg
    32941 acaattttca catcttccga aaatctcgaa tctatgccct tcgatcgtac atccaccgag
    33001 ctgttcttcg aaataattca ttggacacat atggatttct ttcgttgttc cgcacaccgt
    33061 acagataaag tgatggtgat ggccgatttc cccttgacag caatgaaaac gaaacttcat
    33121 ctctccattt aaatcggttt cttccagtaa atcgatttct gcaaaatcat ggagatttcg
    33181 ataaatcgta tcgtaactta ctcctttgaa ttcctgattc atatagtcaa aaacttcttt
    33241 agcggatacg tagcgattgc gcttcactaa ataagttaac aatgcttctc tttttttagt
    33301 atatttaaaa ccgttatttt tcaatgtttc tagtgattgt tcaatcaatg tctgtttttt
    33361 catgacttat tcctccaaat caaaatgatt acgaagtaca cattctagag tatggtataa
    33421 taaacataaa aaaaatgcaa gtgaggtttt atccatgtct tccgattcta cagaaatcat
    33481 tacttttttt gtcatctctg actctgctgg agaaactgcg acaaaattag cgcaagccac
    33541 tatggcccaa tatcctaccg ttgagttcaa tttattccgc agaacatttg tgacagatga
    33601 gaaaacattg atgcaggcac tgcaagatgc actaaaagaa aaagcccttg tcctacacac
    33661 attgatcaat caagaattga tcgagatgac gcgttctttt tgtgaagaac atcaattatt
    33721 tagttttgat gtgatgactc cgccgatatc agaaatcgag cgcttaactg gtatcaagcc
    33781 cattcggcaa cctggcgccc ttcatttatt gaatgagaac tatttcaaac ggatcaaagc
    33841 aatggaattt gctgtaaaat acgatgacgg gaaagatcct cgtgggtttc tagaagcaga
    33901 tgtcgttttg ctaggcgtat ccagaacttc caaaacgcct ttgagcttgt ttttagctaa
    33961 caaaaattta aaggttgcca atctaccttt gatcccacaa gcacatattc ccaaacagct
    34021 ttgggagatc gatcctaaaa aaatcgtggg actgacgaat aacccagata ttttaaacaa
    34081 tatccgtaaa gaacggatgc gctcttacgg attaaatcct gatactgctt attccgatat
    34141 cgaaaaaata cgagctgaac tcgattttgc gaatgatctt tatgaaaaat tgggctgcgt
    34201 agtaatcaat gtcgcttctt tatctatcga agaaacagct tcacttattt tgaatgcttt
    34261 agacctagaa gatcatagtt attatggaac tgaaaccacc gaagaaacag actaacagtt
    34321 tttcttgtct ttttcttaaa aaaactggac tgtgtcagcg aagaagattc gttgatacag
    34381 tccagtttgt ctctatttgc acctatcgtt attgatgttc cacatgtttg agcgtctggt
    34441 tcaaaatatc cagtacgtga gaatcatcaa gactatacaa aatcgctttt ccctcacgat
    34501 gggacttgac gacatggttt tctcttaata aacgcagttg atgcgataca gcagattgtt
    34561 ccatttctac tgcttgggtg attgctgtca cattttgttc cccgtctttc agatacagca
    34621 gaattttgag acgagtgggg tcactcaaca ttttgaatag ttggctgact ttctctactt
    34681 ttgttttttg cgtgtctggc aatccattca cctccaactt gaaaaaagac tgacttctaa
    34741 agtttaccac tttttccatc agtctcaagt ttttttattc ttctgtcatt tttttgataa
    34801 tcgcttcata agcggctact ttttcagctg cgtcttctga agagtttcct tttacaccga
    34861 tataaaattt gattttcggc tcagttcctg aaggacggat agcgatccag ccattttctt
    34921 ccagcgtata cttcaatacg tcagatggcg gtgtcgttag tttttctacg tttccttcac
    34981 ggtctgttct cgtcaactct ttgaagtctt ctgtttggat gacttttgct ccggcaaatt
    35041 ctgtcggtgc ttcttcacgg aatttttcca tcaaagcaga gatttttgca gagccttctt
    35101 gtccgctcat tgtcacagaa atcgtttttt ctgcgtagta gccatatgtt tcaaaaatcg
    35161 tttgcaagcc gtcatacaat gttttgcctt gttttttata gtaagctgct acttctgcta
    35221 ataagagcaa tgcttgaatc gcgtctttgt cgcgaacgaa aggtttaact aaataaccgt
    35281 aactttcttc gaatccgaac ataaaagtat gggaatgatc ttcttcaaat tgttgaattt
    35341 tttcagcaat gaatttgaat cctgtcaata cattgaacat ggtagcccca tagtgttccg
    35401 caattgctgt aggcaattcg ctagaaacga ttgatttcaa taccgctgca ttttcaggta
    35461 aagtgcctcg cgattggtgt gcttccaaaa tatattgagc aaacagggct ccgatttggt
    35521 ttcctgtcaa tacttcatag gagccatttg gcaaacgaac ggctgcgcct aaacggtctg
    35581 catcaggatc cgttgcaatc agtaagtcag cgccttcttt ctcgccaagt cgcatcgcat
    35641 actcgaaagc agagtgttct tctggattcg gtgatttgac tgtagtgaaa tccgggtctg
    35701 cgacagcttg ttctggaact agtacgaatt gttcgaatcc agcttgtttc aacgcacgtt
    35761 cgcccaacat ttttcctgtt ccgtgaagtg gtgtgtacac aagcttcaaa tctttaccca
    35821 ttgtttccac caattcatga tcaatcgtta ctgctttgat ttcttctaga taagcggcat
    35881 ccacttcttc tccgatgatc gtgatcaatc cgctatgttc agcttcgtcg tcagataata
    35941 cttcaacttt taacggattg ctgacttcac ggacatattt cgtcaatgca tctgcgtctg
    36001 caggaggcat ttgtccccca tcttctccgt agactttata tccgttgtaa gctgctggat
    36061 tgtgggatgc agttaccatg attcccgcaa acgtcttcaa atgacggact gcaaaagaaa
    36121 gctctggtgt tggacgtaaa ctttcgaata cataagaagg gatattgtga tgtgctaatg
    36181 ttttggctgc ttccatggca aattctggtg attgatggcg tgagtcataa gcgatagcga
    36241 cacctcggcg ttttgtttct tcaccttgtg tatccatgaa acgtgcaagt ccttctgttg
    36301 cttgtcttac cgtatagatg ttcattcgat tgatcccagg tcctaagatt ccccgcatgc
    36361 ctgcagtacc gaattccaac ggtgcataaa aagcatcttc aagtttttca ggatcttcac
    36421 ccagatcatt taattgtttt tttaagtttt cttctaaatt ttcttcatgt acccattgtt
    36481 catacacttg ttcccaagac atgaaaataa cacctctttc tgaaatatgg ttcttaataa
    36541 gtatagcatt cacttattag atatgaaagt atgaggacca aaaaacgctt aaatcaagaa
    36601 aagattcttt tatcaagcac ggttacaagt attcgcataa atcggattca gtagatttca
    36661 cgcaaaaaaa agagtaaaag aacaattgaa accgttcttt cactcttttt aaacttatgc
    36721 agttgtttct tctaaagatt ccaagtattt atacacttgt tgtccagcaa tcccaccatc
    36781 accaacagca gtagtgattt gtcgcaaatc tttttcacga acatctccga tggcaaaaac
    36841 gcctggtata ttcgtcttca tttcgttgtc tgttggaatc cagccggctt cgttcgtcaa
    36901 cccagcttct ctaaatggtg cagttaatgg atccaatcct acatagatga atactccgtc
    36961 tgctgccaaa tcaaactcat tgccagtttt gacattacgt gctttcacac ctgtcactac
    37021 catttcattt ccaacgattt cgtcaacgac tgtatcccac ataaaggaaa ttttttcatt
    37081 cgcaaatgca cggtcttgga tgatcttttg tgcacgtaat tcatctctac ggtggacgat
    37141 gactacttca gaagcaaatt gtgtcaaata gatggcttct tctactgctg agtctcctcc
    37201 tccgatcact actagacgtt tgttacggaa aaatgcacca tcacaaactg cacagtaaga
    37261 aacgccacgt ccagcaaatt cttcctcgcc aggtacgcct aatttacggt ggatacagcc
    37321 tgttgcgata atgactgttt ttccttcgta agttttatct tcacaaataa cttctttgtg
    37381 gctgccgtga tccttgatat cttgcacgat tccataagca ttttctgtcc caaatcttga
    37441 aacaccttca tacatcttat aagctagatc aggacccatg attgaatcga aaccaggata
    37501 gttttcgatt tctgccgtat tgttcatttg gccgccagga gcgccttgtt cgatcatcaa
    37561 tacggataag tttgaacgtg aagcatataa agcagcagtc atcccagcag gccctgcgcc
    37621 aataacgatt acatcataca tatgtagatt ctcctttact taatcaagta agcatacttt
    37681 acagccaatg cgaaaaaaag tctattgttc tgcttgcgtt tctcgaatag ctttattata
    37741 ctcgaaaaat ccgctgaaaa acaatagact tttataaatc attgatcaat cgttcgaaag
    37801 attttctcca tttgaatcaa ttactttttt ataccagttg aatgatttct tcttcgaacg
    37861 ggctaatgtg ccatttcctt cgttgtcacg atcgacataa atgaatccgt accttttctt
    37921 catctcacct gtaccagctg atactaaatc aatacatccc caagtcgtat agcctaatag
    37981 atcgactcca tctaattcta ctgcatcttt cattgcctgg atatgtgctg ccagatagtc
    38041 gattcgataa tcatcttcca cataaccatt ctcatcgggc gtatcgactg cacctaagcc
    38101 gttttctaca ataaatagtg gtttttgata acgatcataa atatcattca tcgttattct
    38161 caagcctaat ggatcaattt gccaacccca ttcacttgct tccagatatg gatttttgac
    38221 agaagcaaag atatttcctg cagtctgttc caagagttcg ttgtcagtag tcgaaactcg
    38281 agaagaataa taagaaaagg agataaaatc aacagtatgt tctttcagca atgcggcatc
    38341 cccaggttcc attttgatct gaatgccatt tcgttccatt tctttcaatg cataagcggg
    38401 atattctcct cgtgactgga catcaatgaa gaaataattt tctcgatctg actttctaga
    38461 agcccaaaca tcttcaggat tgcaagtgta tggataatat gctcctgctg ccagcataca
    38521 gcctactttg ttctccggat ctacttcatg agcgatcttc gttgcgatgg cacttgcaac
    38581 caactcatga tgtgccgctt gatatttgat ttgttcttca ttttctcctt cttcaaaata
    38641 cagccctgcg cccatgaatg gtgcatgaag gatcatattg atctcattga atgtcaacca
    38701 atatttgaca agtcctttat agcgattgaa gatgactcgg cacagatttt cataaaaacc
    38761 aacgagttct ctggaacgcc acgcaccata ttctttgatc aaatgcatcg gacaatcaaa
    38821 atgtgtaatc gtcacaagcg gctcgatccc gtacttttga cattctttaa agacatcctc
    38881 ataaaatttc aacccagatt catttggctc tttttcatcg cccattggaa aaatacgact
    38941 ccaagcaatg gacatccgat aagtcttgaa ccccatttct gcaaataaag caatatcttc
    39001 cttataatga tgatacatat cgatcgcaat ttttgctgga taaaaatgat tttcatcaaa
    39061 ttcaaacatt ttcttttttc cagtaatgac aggaaaacgg tcttctccga ttggcacaac
    39121 atctacgttc gctaacccac gtccgccttc atcataaccg ccctcgcatt gattggctgc
    39181 tgtagctccg ccccataaaa aatcttttct gaatcccatc atacttcctc cattacatgt
    39241 gtattgcttg ataattctct tgccagttca tcttggactt cgattccttc tgcttttaac
    39301 cggctgattg tttccttgaa ttgcggtaaa tactgctgat gtgcaataaa caactcatcc
    39361 atgatccgtt ttgctgtctt tcctgatcgt ataagcggat tgattgtaaa cgcttgcaaa
    39421 gctgttccat aatcaccagt cacggctgct tcgatcgtca gcaattccat attcttcatt
    39481 acttgcaacc agcctctttc agcagcagga agggaaccaa acgctacatt tcgtgcgcct
    39541 tgtgcgccaa cataggcagt gacttctact acacaatctg ccggcagatc aggaacagct
    39601 ccatcattct ttgtagatac cacgatctgt gtttctttat ttccatagat cgaagcaatc
    39661 gtttcacagg cagcatctga ataataagca ccacctcgtt tttgcaattg ttcaggttta
    39721 tgatccaatt ctggatcttt gtataattca aacagctctg cttctgtttc tttcacttgc
    39781 tgcgctcttg taccaatcgt ttgatattct tctaaagcat gttccagcat ttcttcttca
    39841 cgatagtaat agcggtggta gccacaaggg atcatgttca tttgttttaa ttgttctttg
    39901 aaaaacggga tgtcaaagat atttttcggc aatccattgt cttcatcgta taaacgatca
    39961 atcaattctg ccgtgcggtc atttccttta ttatctgcta ctttgtgcca atggaagtga
    40021 tttagaccgg caaacttgta gatcagctct tcttttttct tgccaagcat tgttggttct
    40081 gtcatcatcg ccattactgg cacattgcat aatccgatca ctttatccca tttgccatat
    40141 ctgataactg cttctgtcac catcccgctt gggttcgcga aattaatcag ccaagcattt
    40201 ggacataaac gcttcatgtc ttcaacgatt gccaaaacca ctggaacggt acgaaaagct
    40261 ttgaatatcc cgccagcacc atttgtttct tgcccaatca tcccataata actagggatc
    40321 cgctcgtctt tgattcgtgc atctaattga ccgacacgaa actgagtcgt aacaaaatcc
    40381 gcatctttca atgcttcttc ccgatccaga gttgcataga ttttgacttc atacggagaa
    40441 gcatcccaca tacgctgaga catctgactg acgatctcaa gcttttcttt tccttcttct
    40501 acatctacga gccagatttc tcgtatcggt aattcctcat atcttttgat aaatccttcc
    40561 atcaactcgg gggtgtaact gctgcctcca ccaatcgtag cgattttgat tccttttgcc
    40621 atgttctcac tcctttactt tttacacttt tattatcttt tttgtaaaca aaacaaacaa
    40681 tagaaattcg tttctttcca gtaacattta caaaagttag tgttttcttc tggatttttg
    40741 taaatatctt gtcaaaaaat gtctttatta agctatataa cataaatccg tttacaaatc
    40801 attttcaaaa aagttataat ttacgtaaaa aaacaagaag aaggtatcta catgttatta
    40861 cgtgaaaaaa tcaaagaaat ctccttttct ccttcagaaa atgaagtgat tcagtttctc
    40921 ttaagcgatt ctccagcact tggcgaaatg accatccaag agattgctga gcgatgttat
    40981 gtccacccgt ccacactcat ccgtgtagca aaaaaaatgg gttttgatgg ctgggtcagt
    41041 tttcgtaatg cttttttagc tgaaacagcc tatcttgaag ggaattttca agacgtagat
    41101 gcgaatcttc ctttttccac cacagacggt attatgacga tcgcaaataa aatggcttct
    41161 ttagaacaga tgacgattca agatacactt tctctcattc atcatgacca actgcaaaaa
    41221 gccaaacaac taatgcttca agcaaaaaaa atcgtgattt tcgccagtaa ctcgaatact
    41281 ttgatttctc aagatttcat gctgaaaatg aagcgcatca aaatggatgt cacgattgtc
    41341 accacttttg gtgaatcgtt ctatgaagcg tacaattgca caagtgatat gtgtgggatt
    41401 ctgatttctt atacgggtga aaacaatgtg atccttcgta ccgcagaaat attgaaacaa
    41461 aatcatgtgc caattttagc tttgaccagt atcggtgatt caacgctatc ttcaatgagt
    41521 acagccgctt tgcgacttac gacacgcgaa cgactgtatt cgaaaattgg taattttacg
    41581 atcaatacat cgatttgtta tcttctagac gtgttatata gttgtgtttt tgcagaaaat
    41641 tatcaacaga atttagtcca tctaatttct gtaggacaaa aatttgataa acgccctatc
    41701 agctcagcca tcatgaaaga gcctttcaat tttgaaaata aagaagtgga ctaaaaagaa
    41761 tagttaagcc tagtccattc tttcacctaa ccgttcaggt cagtgcggtg ataagtgcat
    41821 cgtctggccc gaccgtttcc ccttgatttt ccaaaatatc caaataatcc atgtaattga
    41881 tgacaatcac aggtgtttct aaactgtatc cttcctcttc gattttcttt ttgtcgaagc
    41941 gaagcaacag atcgccttgt ttcactcttt ctccttgctg caccaagctt tcaaaatatt
    42001 tcccttccaa ctgaacagta tccaatccga catgaatcag caattccaga cctgcttcag
    42061 aaaccatccc gattgcatgt ttcgtcggaa acagggacat gactgttccg tcaaaagggg
    42121 cacgtacttc tcctttttca gggtagatca agattcctcg acctagtgtt ccttgtgcaa
    42181 aagctgcatc ctttgctgca ttcagtggag cgatttgtcc ttgtatcggt gtttttacaa
    42241 tttctttacc tgatcttttc tgtctatcat ctgtttcatc tgcttcctcc ttccaaaaga
    42301 aaaaagtcag cgcaaaggat accaccatcg caatggcgat cccaatcaat acattaatca
    42361 catctgttaa atcaccatct ggtctaatat agttgggaat tgtaaagatg cctagtccac
    42421 cttgattcca agaagttaaa ttcattaacc cactatacgc gccccctaac gcaccaccga
    42481 cacaggtaaa aataaatatt tttttacgtg gcaatgtaaa cccataaata gctggctctg
    42541 taatccccac aataccagaa acaatggctg gtattgcaat tgctttgtct tttggatttc
    42601 taagcttaaa gtagagtgcg gtaagtgctg cagtttgtcc aaaagacact actgcaacag
    42661 gtgtcataat attttgccaa ccattcacag aaaattgcat caatcccatt ggtacgattg
    42721 cccaatggag accaaacatc accagaattt gccagaagaa gcctacgatt gctccataaa
    42781 taactggcga aagtgctaaa agtgtttcaa atccagccat taaaatatca gttgcgaatg
    42841 tgaatactgg tccaacgagt aaaaaaccta aaggcattgt aataagaacg gtgaagaatg
    42901 gaacgaagaa attcgcgatc atctcaggta ctaacttttt aattggtttc tgaatttggc
    42961 tagctaacaa cacaataaag ataatgggaa tgacagaaga agcgtagtta cgcgcaatcc
    43021 agggaatgcc gaatactgtt tgataaatag gtgcttcaaa aatagtgcca gaaaatatgg
    43081 tcgttagtgg tgcttctgct gcaccactca aagcttccag cgacaagcta ggattcatta
    43141 atgctgcgcc aagcaacatc cctacgaatt catttacttt aaatttacgg gcagctgtta
    43201 aaccgataat aacaggcata aattggaata cagaatcacc gatattatca aacataacaa
    43261 atgtgccaga accgcggtca aacgcgccta agaagacaag gaatgctgtc agtccacgaa
    43321 tcatcccgtc agcagctagg atagcaagga atggttggaa acagcccgat attccatcaa
    43381 taagcatatc aaacggtctc attttttctg ttgaaacagc ctcatcaaaa gtaaggtttc
    43441 ctgcttttat aacctcttca aacacgactg gcacatgatt cccgatgaca acttgatact
    43501 gccctcccgc tcgcattacc gttacaatac cgtccatatt tttcaagatc tcatcatttg
    43561 ctttttcttc gttttttaat ttgaaacgaa gccttgtgat acaatgtgtc aaaccattga
    43621 tattttcctt cccgccgaca ttttctacga tttttctcgc taattcttgg tattttccca
    43681 tttctattcc ctccaattta ttagtggaag gtttagccaa ctgaatgtca ctacccttat
    43741 ttcatacgtt cttgttaatt tatcctcctt tttttattta tttacaacga ttctcatgca
    43801 ctaaacgcgc agtatggatc gttaaataca ttttttcgtc cgtggacatc tggtagttga
    43861 acgtctcggc taaaaagtct gctattttct caacgcaacc aaacgtatcc ttatattttt
    43921 tttgaataac ctgaaacaat tcctcagaaa cttctcccac ttctgatttt tctccatcta
    43981 ggacgcgtgt cagaaaaaaa cgtaagtgtg tgacgaatcg aaaaaaatgg actgaatctt
    44041 catcaaatgt aatcttatag taatagcgga cgatatttag aatatcctgt attgttatag
    44101 tgaacaggta ggtattgtct tgttggcttt gaatgccttg tgcattgact aaatgcaatg
    44161 cgataaatcc ggcttcatct tctgataact tgatgtggta tttatccgag attttcttca
    44221 ctgttttttt tcccgatggc atactcttta ggaaatagtt gtttgatatc atacagcaat
    44281 acatttggta caaatattcc cattttgtga cgttcgatag ccgtatacaa atgatccgtc
    44341 aatgcaatat acacagaatc attcaactgg acttgtagag cctcttttgt atattcaatg
    44401 atttcacaag aaatttctaa gtactcaaga ggaatcgctt gtgccaattc ttggaactgt
    44461 tgtgaaagcc cgtcatttgt caactgaaat tttttgtcga tgcatgagtc aaaaatcggg
    44521 tcacccactt tctttttgaa tgccaaacct tttcccatca cgatcatttc ctgatttctt
    44581 tcatccctgg ttattacgac gttgttattc agtactttct caatcagcat gttttgctcc
    44641 tttccatgat atatagggct gtatccaaaa caaaaagaaa aacccaaaaa gccgtccatg
    44701 gaaccatggg agactcatca ggtttagctt gcatcaggca atcactatcc aagttgtatc
    44761 gttttcttta tattatcgaa agcaaacgct tttgtcaacg ctttcttagt ggttattagc
    44821 cgcttttgac tagctgtcgt cgtctttttt aaatcgggtg actacgccac taacgctcac
    44881 agatgaagaa tctgcgaagc tctgttttat tttcactcta gcgcttaggg caaaatgcta
    44941 ctatgctact gtcacaacct ctttttacac accactgctt tgcagtttgt acatatctgc
    45001 atacaaacca ttttgcgcta gaagtgtttc atgattccca cgctctacta tatgaccttt
    45061 gtctaaaact aaaatcaatt ctgcatcccg aatcgtggac agccgatggg caatcgctat
    45121 cgttgtccgt ccttgtcgca tttttgccaa tccttcttgg atcaatcctt cggtttcagt
    45181 atcgatattt gctgttgctt catccaatac tagtatttta ggatctgtca cgattgttcg
    45241 cgcaaaagtg atcagctgtc gttgtccact agaatagctg gcaccgtgtt cgatcacttt
    45301 tgagtgatat ccttttggta attcatcgat gaacttgttt gcttgaacaa actcagctgc
    45361 atggcgaatc tgttcgtctg tgatagctgg attcatcatc cggatatttc ctgcaatatc
    45421 tccataaaac aagaaggcat cttgcaagac caatcccatt ttcttacgta actcttccat
    45481 tggatattct cgaatgtcat gatcatcaat caagatttgg ccttcataaa attcgtaaaa
    45541 ccgcatcaat acgttgatga tcgagctttt tccgcttccg gtgtgcccca ctaatgcaac
    45601 ggtctcaccc ggattagcga caaaagagat attgttcaat acattgtgct ctccatcata
    45661 agaaaagctt acattgcgaa actcgatctt acctgaagta atcgcttgat ctgctccagg
    45721 attttgttgc ggtgcatatt cttctgtatc catgattttc aaaatacgac taccggcaac
    45781 catcccatct gtaaaggtgc tcaaaaagtc catcatttga gacattggat taaaaaattc
    45841 ctggacatag gtcgtaaatg catagatcag tccaacttct acgggagaat gcaacgcatc
    45901 gatcccaaac aaagtcaacg ccaacgcaat cgccaatgca tagagaaaat tgatgattgg
    45961 acttaacaga atcgaattcg ttttgatcat cgcatagcgc gtgtctaaat actcgttgtt
    46021 cacttgttca aattctttag ctaaacgagc ttcttggcga aactgctgga taatacgcat
    46081 gccggaaatc gattcattca atttcgtgtt cagctgactt aatttttccc gcatatttcg
    46141 gtaaatacga gaactgaatt tctggtaata ccagatgacg attcctaaaa tcggcaagaa
    46201 caccaaagtc cacaaggcaa tttctccatt gatttgaaac atggcaacga aagaagaaac
    46261 gactgcaaag atcccagtca ataccatcaa aaagacatac caaaattcaa atagcgtttc
    46321 tgtgtcattc gtcactcgag aaacggtcga tcctgccggt gtctggtcaa aataacgcat
    46381 acctagtgta tgcagctttt caaataatct tacccgaaca tactgatagg tcttcaatga
    46441 agccatggaa tacaaatacc attggaaaaa ccaaatgata cttttgacta tgactccaaa
    46501 caagtacaca ccagcaaaaa acaaaataac ttgtgtcgta gctgactgtt tagccagatg
    46561 atcatccata aaagtttgga tgatccttgg caataggaca ttgatcacag acagggcaaa
    46621 cgcaaataag atagcaacga tgaacgttct tctaaaaggt ttggcgaact tcatcagtcg
    46681 tttgatgatc ttcttctgtt ctttaagtgg aatcgatttt gtccattccg attgataatt
    46741 ttcatccatc aggcctcgcc tccttctatc ttcgcttcta attgctgttt ttcccacatt
    46801 cgttcatacc agccacctaa tgcaagcagc tcgtggtggg ttcctcgttc aatgattttc
    46861 ccttgatcga caacaatgat ttcttttgca tgcatcacgc tgcttaaacg gtgagctgca
    46921 atgatggttg ttttctcttt tcttatttct tttaaattat gcaagatagc ttcttctgtt
    46981 ttggcatcta ctgcagaaag tgcatcatct aagatcagca attcaggatt tttgatcaat
    47041 gctcgagcaa tcgaaatcct ctgtttctgt ccgccagata aagagactcc acgttctcca
    47101 actaaggtat cataaccttt tggcaattcc ttgatttcat tgttgataaa tgctaaagaa
    47161 gccgcatgct ctacttcttc ttctgaaagt tttggattag aaaaacggat attatctcga
    47221 atggtcatcg aaaacaggaa gtgatcctga ggcacataac cgattgatcc taataaagca
    47281 ttcaatgaat attctttgat cgaacgtccg ccaaattgga ttttcccttg ataatcatcg
    47341 tattcacgca tcagtaattt gatgattgtc gtttttcccg caccagtttt cccaacaata
    47401 cctaatgttt ctccttcttg gatcgcaaat ttgatttgtt ctaatgctgg tgattcttct
    47461 ttcggatagt taaaagagga aatagctaca ttcagctcgc cttttgccgg ggtctgcact
    47521 gcacccagtt gttccacgat atgcgtcttt tcatgcaaaa gttcattgac gcgatcataa
    47581 gaagcatttc ctctttccaa tacgttgaac aatcgaccaa tcgcaaacat cggccaaaca
    47641 agcataccga tatagctaat aaatgagacc atctgcccga ttgagatcgt gccttccaag
    47701 acatactttc cacctaaaat aattgttgca acataagaca gaccgataat caaggtaatg
    47761 aatggatcaa ataaggagtc taaaaaattg actcgtttgt ttttaataat tgcatcttca
    47821 atcttttctt caaaatccgc gagatcttct ttttcttgtc caaatgtttt aatgactttg
    47881 atcccagtga tactttcttg tgtcttatca ttgatactag aaaaagcttc ttgcgaatca
    47941 cgaaaagcat cgtggagttt tgaccccagc actcgtgaag taacggctag caaaggcaga
    48001 ggaatcagcg caatcagtgt taagcgccaa tcaataaaca aaatcatcgc aatgatcgtt
    48061 gttccgcccg taatcactga atctgcaaag gtcaagattc cagctcctgc tacattctgg
    48121 attgcattca aatcattcgt tgcatgagcc atcaaatctc cagtccgata tttttggtaa
    48181 aagagattgt ccatttctgt aaaatgtttg aatagctgct gccgaagttc tctctccaac
    48241 cgagctgcac ttccccaaat attcgtccgc cagatataac gaaaaagata ttgtaagaaa
    48301 gctgcaagga tcaataataa gatccaccag gaaatgatct ttattgataa attcttatcg
    48361 gcgatctcat caatgatgat cccaatcact tttggaggaa ctaactgtac caaggccact
    48421 gcgaataggg agaaaatccc aattaaataa tgtttctttt cctgacgaaa aaaccaacct
    48481 aattttctaa aaatcgacat tttactcctc ctttgtcttt atcaagagca taggattgtc
    48541 tgtgcttgtc ttttttgctg aatagtctga atagtctaac aaattacgaa ataaaaaacg
    48601 gactgaaaaa atcagcccgc aaaaagtctt tgggtcagaa cctatttttt cccttggttc
    48661 ttcatttgct gcatcatctg gcgaattttc ttctcagatg gtttttgccc cattgacatc
    48721 atcattgatc gcaacatgtc ctcattaacg ggaggatttt tttctaaata gtctttcata
    48781 tatttacgcg ctaggaaaaa gccacctact gcgccgatta gcaaagcaat aatagcaata
    48841 agtacgacaa tacctgttga taccatataa atctctcctt tctatttccg aattgctctc
    48901 aatgatttat tttactaaag tttattgaaa aaagaaaggc gtattcttta gtttcatgca
    48961 aaaaatagtg gtttttttag agaagaacaa aatttctttc attaaccagc aagacacacc
    49021 acgaaaaaaa attaggcata ccgaatcttt ttctttaatt ttttctttct gaggtgtaga
    49081 atgtaatcgt agataaatag gaaaggtggt tttttcttga ataatcaatc caacaaacaa
    49141 tttcataagc atcgacttat tgaacataca aatggtttat ctttagctga agtaaatgga
    49201 acagtggatg taccaaaggg aaaaagtttt tttaaaacac ttcttgctta ctctggacca
    49261 ggtgcattag tagcagttgg ttatatggat ccaggtaact ggtccacttc gatcactggt
    49321 ggacaaaatt tccaatattt attgatgtca gttattttga tgtctagtct aattgctatg
    49381 cttttacagt atatggcagc aaaattagga atcgtgaccc aaatggattt ggcccaagca
    49441 atccgagcac ggacaagtaa gacattgggt gtcattttat ggatcttgac tgaattagcc
    49501 attatggcaa cagacatcgc agaagtcatt ggtgcagcaa tcgccctcta cttacttttt
    49561 gatattccat tggtgattgc cgtctttatt actgtattag atgttttcgt tctcttacta
    49621 ctgacaaaag tcgggtttcg taagatcgaa gcactggttg tctgcttaat tttcgtcatt
    49681 ttattcgttt ttgtctatca agttggcttg tctaacccag attggcacag tttatttgct
    49741 ggctttatcc ctaacagtca tacattctca gactcaccgg tcatcggcgg cgaaactccg
    49801 ctgactggag ctttagggat tattggtgca acagtcatgc cgcataactt atatcttcat
    49861 tcagcagttt cacaaactcg gaagatcgat caccaaaacg aagaagatgt agcacaagct
    49921 gtacgttttt ctacttggga ttctaatatc cagttgtcaa tggcttttct agtcaatgca
    49981 ctgctattga tcatgggtgt cgctgtcttc aaaaccggtt ctgtccaaga tccttccttt
    50041 tttggtctgt atgaagcttt atctgatcca tcagctatga gcaatggtat tttgattgct
    50101 gtagcaaaat ctggtatctt gtccacttta tttgctgtag cacttcttgc ttctggccag
    50161 aactctacta ttactggtac gttgaccggt caagtcatca tggaaggatt catccatatg
    50221 cgtatcccga tttggctaag aagactggtc acacgattgc tttctgtgat tcctgtattg
    50281 atttgtgttt tgtttacaag tacaaaagga acgatcgaag aacatgccgc tttgaataac
    50341 ttaatgaatg aatcccaggt gttcttggct tttgcgttgc cattttcgat gattccttta
    50401 ctgatgatga ccaacagcca agcggagatg ggtagccgat ttaaaaattc attcatcgta
    50461 aaacttcttg gctggttctc tgtgattagt ctaacttact tgaacttacg aggattacca
    50521 ggacagatcg aaagtttctt cggcgagcaa gccacttccg ctcaactagc attggctgat
    50581 cacatcgctt atgtaatcat tgttcttgtc cttctcctgt tggcatggac gattggtgat
    50641 ttatataaag gaaacaaaaa atatgaacag cttttgcagg aaacggtaga agaaatcgaa
    50701 taaaaactga tttttccaca caaagaccct tgatagttag gttaaaaatc tagctaccaa
    50761 gggtcttttt atttagaaga taaagctttt ttcagattta atttactgaa aactagcatg
    50821 cttgttacta cgatgaattg cgttaatggc acgcctgcac cagtgtagac acttaaaaaa
    50881 tagtcctttt tttctggcgc ataagaacaa aaccatgaga caccgaaaag aaaaaccaat
    50941 tgtgtcagta ttaatccggt gaccacaatc aaagaggaac tataataggc acgatcagct
    51001 tttgcaaata cggttcctag tatcataagt aatatccctg ctattgaagc aatcagcacg
    51061 ggaatagcca gaacttggta aatttttatg atgacattcg cgacttttgc tgattttgtt
    51121 aattggaaat taggtgttct cggttcatta ctatcgatcc aattctccat tagcggaagg
    51181 tttaataatt cttgagcctg tttgacttgt tcttgcgttc cgaaactata atttcctcct
    51241 tgatggaaat ctttatatcg ccatgcataa gcgtatcctg attgaaggaa atcgaatacg
    51301 attggcagat cactcatcgt ctttccatct cctgatccca tcagatagaa ctcttttttc
    51361 tttttgatgg ttcccttgtg ataggcttct tctaattctt ggttgacttt tttccaaaaa
    51421 tcattggttt cttttgcatt gttttggtaa taaccagatt cgcttaccac atctcgcaat
    51481 gcccaaaaga tgatatctcc gggtaattct tttacttttc caccttgagt ccacgcgtga
    51541 gtcgtatata attcgtcaat acgggtagaa acagtatgga atgtaggaga tgcggctaat
    51601 gctttattta gtgcagcatg tgagacccat atctcactgt tttctttatt caagttcgtt
    51661 tcatcatcta ttcggatcag ttgtttcatc aaacgtccaa attctccact ggaacggtca
    51721 ttgatggttg caataccgta tgttgtctca tttttatatt cgatccactg atagacgatg
    51781 gaaaagccaa ctataggaag taaaaacaat gaaagtttca gccattcccg tttcgagaga
    51841 agaaagagtc gtttttttaa cttctttact tctttgaaag aaaagtcttg ccctagcaag
    51901 atctggacga aactgatacc caaagctact acagtaaaag gaagaagcca gatagaatct
    51961 tcgcgaatga accaaaagaa aggaaaagcg acagaaagcc ctaaaaacca tggcagcaat
    52021 tttctgctag aaccgtattt gcggtaataa atagctaata aacaagcgat aatgatctca
    52081 acagccggaa tcacgagggc attacgatat gttcgagtgg aatattcatg tgtaaaacta
    52141 atcggagaaa acaaaaaata aaaatagata cttaaaagaa gatacttgtt cttcacaatc
    52201 ggtttaaacg cgagtgcaac caatatactg gcaaaaatac tgaacatgcc gaacaaaact
    52261 gcataagaaa gatgcagttt atgtgcaagt actaaaaata agctgtagga gattcctttg
    52321 gaaagtgttg tagtcgtata ctcccctagc catttaccat ccaaaatatt ttgagcatag
    52381 tgaatcagca gctgatcatc ataggtcgcc gacatatctg ttccatagat tgctttacta
    52441 tataaataca accgaataat tgtaaataat acggctatgc caagaataaa gtatgtatgt
    52501 ttctttttta gttggtcgat caaggggttt aaaatgttca gcatcttttc gtcctttcaa
    52561 tcacgttttg ctacttgttt gtgaaacttt tcgtttttta cttttctatc agtataccct
    52621 gtttgtctga atttaaaaag agggggcaaa aggagcatgg cgaaaacgaa tgcaaaaagc
    52681 actcctttgt ttcttaaaca aaaaaggaca aggcagactg cccaatcctt ttttgttgct
    52741 gtcaggtaga aaacttaaag tgtgacttct tctgctaata actcagggaa cacttcggga
    52801 tcgaatgctt gcgctttgaa catggaaatt tcttttccat atggtgcgta agctttcttt
    52861 ttatctttac cgacatatgg ggtttctaat attttcgaaa tgttgtcaaa cattggatca
    52921 tggacgattt tgttcaatgt gtcaaatcca attgttccaa aaccgatatt ggcatgccga
    52981 tctttatgag aaccttgtgg atttttagaa tcattgatat gcagtacttt aagccgatct
    53041 aatccgatga ccttatcaaa ctcttccatt acacctgaaa aatcttcttt tatattatat
    53101 ccggcatcat tcgtatgaca tgtatcaaaa gtaacggata atttttcatt caattttact
    53161 ccatcgatga tttgcgctaa ttcctcaaat gttcgaccga tttccgtacc tttccctgcc
    53221 atcgtctcca aagcgatctg tgccgtctgt tcttttgtca aaacttcatt caacccctca
    53281 ataattctag caatcccagc ttctgcccct gctcctacat gagcgcctgg gtgaagggtg
    53341 atttgagtag cacctaaagc ttccgcacgg acaatctctt ctctcagaaa ttgtacagca
    53401 aatggaaaca tttctggttt gatcgtattt cccaaattaa tgatataagg cgcatgaacg
    53461 acgatatttg ttagtccgtt ttctgccata aatgcttttc cggcatcaat attcatctct
    53521 tcgatagctt ttcttctagt attttgagga gcgcctgtat agatcataaa ggtcgaagat
    53581 ccgtaactgg ctgcttcttc tgccgcgcct aacagcattt tctttccgct catgctgaca
    53641 tgtgagccta ataacatgga tggattcctc cttgaaaggc aattgtttcg aacaattcct
    53701 gtatattgat aagatgatgt acaaagaaaa tggtttgttt ttctttgccc tgttctccat
    53761 agtaactgaa actttcccta aagaaaagct taagaactct ttcataaaaa agatcatttc
    53821 ctcacgtttt atctcattcg aaaaagaaat tcctgtcaaa aacagccttg tctgtttttt
    53881 tgtcctatta tttgctataa ttagcgaaat aaaaccatta gttgaggtga cccttttgcc
    53941 acgcaaaaat actcgaaaaa aacagaatag aagaaaaaaa gaaaaatggt ttgttcctaa
    54001 gattattttt agagtgtttc aatcattgac tgtttttatt actgttcttc ttttgttgtt
    54061 cgcagctcta ggtatcggaa taggtgctgg ctactttgcc tatcttgtcg aagacacaca
    54121 attgccgact aaaaaagaac tgcagacaga actaggaaac attacggaaa cgtcaaagat
    54181 tgtttatgca gataatacag agatatcaaa aatccagaca gatctgatgc ggacgactat
    54241 ttcatctgat aagatttcgc ctttattgaa aaccgcgatt atcagtacag aagatgaata
    54301 cttcgataaa catcaaggtt atgtccctaa agctgtttta cgagcactag tttcagaagc
    54361 gactggcatc ggctcgtctg gaggatccac tttgacacag caattagtca aacaacagat
    54421 cctaaccgat gaaacaacat tcaaacgtaa agcaaacgag atcgttcttt ctgcacaagt
    54481 agaaaaacac ttttcaaaaa atgagatcat tactacgtat ttgaatgtct caccatttgg
    54541 tcggaataat aaggggcaaa atattgctgg agtccaggaa gctgctagag gaatctttgg
    54601 tgtagatgca aaggatgtga ctctgccaca agctgcttat atcgctggtt tgcctcaaag
    54661 ccctatcacg tatagtccat acacgaatac aggcgcgcta aaagaagatc tttctgccgg
    54721 tcttgccaga aaagattttg ttttattcag tatgtaccgt gaaggacaaa ttacgaaaga
    54781 acaatacgaa gaagcgaaag cctatgatct tacaaaagac tttctcccac aacaaatcgc
    54841 ggaacagact gacagagaat tcttgtatta taccgtgatg aacgaagcaa caaggattat
    54901 tgcacaacaa ttggcagaaa aagataatgc tgatatgtca gattcatcgg tcagtgaagc
    54961 ttattatcaa aaagcacagc aaacgatcca aaacaaagga tatacgatcc attcgacgat
    55021 cgataaagat atctatgctg cattacaaac cggcgtagaa aattatggct acatgttaga
    55081 tgatggtgct ggtagccaag tggagactgg aaatgtattg atggataaca gaaccggacg
    55141 tatctatggc ttcgtgggtg gtcggaatta cagccagaat caaaataacc acgcctttga
    55201 tacagaacgt caagctggtt catccatcaa accggttctt gtttacggtc ctgcaatcga
    55261 tatgggactt gtcggatcag aatcccgtgt atcagattat gcaacgactt ggcaagaagg
    55321 aaaaaatgct ggtgagaaaa tcgtcaatgc gaccaatgaa gggtcgaaca ccttccaaac
    55381 cgtccgtgag tcactggaat ggtccaacaa tatcccagct tatcacttat atcaagatgt
    55441 gttgaattcc ggtggatcga aacaatacgc ttacgagcac tacttggcga agatgaacta
    55501 cccagcaaat gataattggg gcgttgaatc ggctccttta gggacagtag atgtaacgac
    55561 gcttcaacag acaaatggat tccaggcctt agcaaatggt ggagtctacg aagaaggcta
    55621 tatcattgat tccatcacag ataatgcagg taatgtgatt tataaacatg aaagtaattc
    55681 tgtccgtatt tattccgaag caacggcatc gatcatgaat gacatgatgc gtagtgtgat
    55741 caatgaaaaa atcactacac cattcaaaga tgtcatctca agcttaaacg gaaatctagg
    55801 aaatgcagat tgggtcggaa aaactggttc taccaatgaa taccgagatt catggctgat
    55861 cgtctcaact ccatctatca ctatcagtag ttgggcagga cacgatgaca atactggaat
    55921 ggacagccaa gcaagaatac gttcggctaa ttatcttgcc aatctaatca atcaagctta
    55981 ccaagcaaac cctgagattt tcggcactga tgagaaattt gacttatcat ccgatgtgat
    56041 gaagaaaaaa gtatctgggt tcacaggaca aacagctgga aaagttactg tcaataaaaa
    56101 atccatccaa acgccaggaa aaacagtgga gtcactttgg gcaaaaaatg gtccgaagaa
    56161 aagcgccttt aaattcggcg taggcggtac tgatgaaaac tatacagatt actggaacac
    56221 cgcttcagct tatgctagag cgaatccaga gaccaaagaa tcagacgata aagatgattg
    56281 atctaataga ttaatcagaa ttaaagggag ctgcgacaaa aatcttgtca cagctccctt
    56341 tttccgaata aatggtgttc aaaagcttac atctacgata ttaagacaaa tttatgtaaa
    56401 aatgtgaaaa ac
//
LOCUS       DAFEML010000012        56385 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFEML010000012
VERSION     DAFEML010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.012"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            330..1175
                     /locus_tag="LP468_000837"
     CDS             330..1175
                     /locus_tag="LP468_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2080393.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="LP468_000838"
     CDS             1456..2676
                     /locus_tag="LP468_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL2080394.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="LP468_000839"
     CDS             2673..5393
                     /locus_tag="LP468_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2080395.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="LP468_000840"
     CDS             5377..6321
                     /locus_tag="LP468_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2080396.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="LP468_000841"
     CDS             complement(6390..7400)
                     /locus_tag="LP468_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2080397.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="LP468_000842"
     CDS             complement(7580..7924)
                     /locus_tag="LP468_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2080398.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="LP468_000843"
     CDS             complement(7917..8351)
                     /locus_tag="LP468_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL2080399.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="LP468_000844"
     CDS             8489..9226
                     /locus_tag="LP468_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080400.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="LP468_000845"
     CDS             9219..10430
                     /locus_tag="LP468_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080401.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="LP468_000846"
     CDS             10634..11416
                     /locus_tag="LP468_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL2080402.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="LP468_000847"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="LP468_000847"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL2080403.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LP468_000848"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LP468_000848"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL2080404.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="LP468_000849"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="LP468_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL2080405.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="LP468_000850"
     CDS             15018..16067
                     /locus_tag="LP468_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL2080406.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="LP468_000851"
     CDS             16064..16342
                     /locus_tag="LP468_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL2080407.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="LP468_000852"
     CDS             16317..16787
                     /locus_tag="LP468_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL2080408.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="LP468_000853"
     CDS             16804..17106
                     /locus_tag="LP468_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080409.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="LP468_000854"
     CDS             17123..17494
                     /locus_tag="LP468_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL2080410.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="LP468_000855"
     CDS             17466..17825
                     /locus_tag="LP468_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080411.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="LP468_000856"
     CDS             17997..19004
                     /locus_tag="LP468_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2080412.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="LP468_000857"
     CDS             19029..20213
                     /locus_tag="LP468_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL2080413.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="LP468_000858"
     CDS             complement(20650..22233)
                     /locus_tag="LP468_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2080414.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="LP468_000859"
     CDS             complement(22811..22954)
                     /locus_tag="LP468_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL2080415.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="LP468_000860"
     CDS             complement(23177..23656)
                     /locus_tag="LP468_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2080416.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="LP468_000861"
     CDS             complement(23729..24013)
                     /locus_tag="LP468_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080417.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="LP468_000862"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP468_000862"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="LP468_000863"
     CDS             complement(24357..25643)
                     /locus_tag="LP468_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL2080418.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="LP468_000864"
     CDS             25781..26452
                     /locus_tag="LP468_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL2080419.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="LP468_000865"
     CDS             26418..26906
                     /locus_tag="LP468_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL2080420.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="LP468_000866"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="LP468_000866"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL2080421.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="LP468_000867"
     CDS             27867..28631
                     /locus_tag="LP468_000867"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL2080422.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="LP468_000868"
     CDS             28864..31077
                     /locus_tag="LP468_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL2080423.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="LP468_000869"
     CDS             31088..31534
                     /locus_tag="LP468_000869"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL2080424.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="LP468_000870"
     CDS             31705..32964
                     /locus_tag="LP468_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL2080425.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="LP468_000871"
     CDS             complement(33053..34000)
                     /locus_tag="LP468_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2080426.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="LP468_000872"
     CDS             34394..35686
                     /locus_tag="LP468_000872"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL2080427.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="LP468_000873"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="LP468_000873"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL2080428.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="LP468_000874"
     CDS             37579..38454
                     /locus_tag="LP468_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2080429.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="LP468_000875"
     CDS             38720..40603
                     /locus_tag="LP468_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL2080430.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="LP468_000876"
     CDS             complement(40678..40962)
                     /locus_tag="LP468_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2080431.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="LP468_000877"
     CDS             complement(40952..41686)
                     /locus_tag="LP468_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL2080432.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="LP468_000878"
     CDS             41815..42438
                     /locus_tag="LP468_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL2080433.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="LP468_000879"
     CDS             42630..43751
                     /locus_tag="LP468_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL2080434.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="LP468_000880"
     CDS             43758..46886
                     /locus_tag="LP468_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL2080435.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="LP468_000881"
     CDS             46905..50099
                     /locus_tag="LP468_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL2080436.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="LP468_000882"
     CDS             complement(50245..50952)
                     /locus_tag="LP468_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2080437.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="LP468_000883"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="LP468_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2080438.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="LP468_000884"
     CDS             52447..53100
                     /locus_tag="LP468_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL2080439.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="LP468_000885"
     CDS             53326..54324
                     /locus_tag="LP468_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL2080440.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="LP468_000886"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="LP468_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL2080441.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18554 a         9728 c        11686 g        16417 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttt
//
LOCUS       DAFEML010000013        53224 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFEML010000013
VERSION     DAFEML010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.013"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            380..3187
                     /locus_tag="LP468_000887"
     CDS             380..3187
                     /locus_tag="LP468_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2080442.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3378..3869
                     /locus_tag="LP468_000888"
     CDS             3378..3869
                     /locus_tag="LP468_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2080443.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3972..4961
                     /gene="manX"
                     /locus_tag="LP468_000889"
     CDS             3972..4961
                     /gene="manX"
                     /locus_tag="LP468_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL2080444.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPDVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4994..5797
                     /locus_tag="LP468_000890"
     CDS             4994..5797
                     /locus_tag="LP468_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL2080445.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5818..6732
                     /locus_tag="LP468_000891"
     CDS             5818..6732
                     /locus_tag="LP468_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL2080446.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6815..7189
                     /locus_tag="LP468_000892"
     CDS             6815..7189
                     /locus_tag="LP468_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL2080447.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7328..7573
                     /locus_tag="LP468_000893"
     CDS             7328..7573
                     /locus_tag="LP468_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2080448.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7745..8809
                     /locus_tag="LP468_000894"
     CDS             7745..8809
                     /locus_tag="LP468_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2080449.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9055..9480
                     /locus_tag="LP468_000895"
     CDS             9055..9480
                     /locus_tag="LP468_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2080450.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9473..9922
                     /gene="nusB"
                     /locus_tag="LP468_000896"
     CDS             9473..9922
                     /gene="nusB"
                     /locus_tag="LP468_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL2080451.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10019..10873
                     /locus_tag="LP468_000897"
     CDS             10019..10873
                     /locus_tag="LP468_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL2080452.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10874..12211
                     /locus_tag="LP468_000898"
     CDS             10874..12211
                     /locus_tag="LP468_000898"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL2080453.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12216..12440
                     /locus_tag="LP468_000899"
     CDS             12216..12440
                     /locus_tag="LP468_000899"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL2080454.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12442..13332
                     /locus_tag="LP468_000900"
     CDS             12442..13332
                     /locus_tag="LP468_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2080455.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13341..14159
                     /locus_tag="LP468_000901"
     CDS             13341..14159
                     /locus_tag="LP468_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL2080456.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14266..14715
                     /locus_tag="LP468_000902"
     CDS             14266..14715
                     /locus_tag="LP468_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2080457.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14733..16415
                     /gene="recN"
                     /locus_tag="LP468_000903"
     CDS             14733..16415
                     /gene="recN"
                     /locus_tag="LP468_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL2080458.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16470..16586)
                     /locus_tag="LP468_000904"
     CDS             complement(16470..16586)
                     /locus_tag="LP468_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL2080459.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16659..17615)
                     /locus_tag="LP468_000905"
     CDS             complement(16659..17615)
                     /locus_tag="LP468_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2080460.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17786..18154
                     /locus_tag="LP468_000906"
     CDS             17786..18154
                     /locus_tag="LP468_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL2080461.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18324..18755
                     /gene="mraZ"
                     /locus_tag="LP468_000907"
     CDS             18324..18755
                     /gene="mraZ"
                     /locus_tag="LP468_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL2080462.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18776..19735
                     /gene="rsmH"
                     /locus_tag="LP468_000908"
     CDS             18776..19735
                     /gene="rsmH"
                     /locus_tag="LP468_000908"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL2080463.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19740..20141
                     /gene="ftsL"
                     /locus_tag="LP468_000909"
     CDS             19740..20141
                     /gene="ftsL"
                     /locus_tag="LP468_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL2080464.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20142..22334
                     /locus_tag="LP468_000910"
     CDS             20142..22334
                     /locus_tag="LP468_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2080465.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSVYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22360..23322
                     /locus_tag="LP468_000911"
     CDS             22360..23322
                     /locus_tag="LP468_000911"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL2080466.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23336..24697
                     /locus_tag="LP468_000912"
     CDS             23336..24697
                     /locus_tag="LP468_000912"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL2080467.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24723..25811
                     /gene="murG"
                     /locus_tag="LP468_000913"
     CDS             24723..25811
                     /gene="murG"
                     /locus_tag="LP468_000913"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL2080468.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25826..27046
                     /locus_tag="LP468_000914"
     CDS             25826..27046
                     /locus_tag="LP468_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL2080469.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27202..28527
                     /gene="ftsA"
                     /locus_tag="LP468_000915"
     CDS             27202..28527
                     /gene="ftsA"
                     /locus_tag="LP468_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL2080470.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNIKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28550..29791
                     /gene="ftsZ"
                     /locus_tag="LP468_000916"
     CDS             28550..29791
                     /gene="ftsZ"
                     /locus_tag="LP468_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL2080471.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29808..30485
                     /locus_tag="LP468_000917"
     CDS             29808..30485
                     /locus_tag="LP468_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL2080472.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30499..31098
                     /locus_tag="LP468_000918"
     CDS             30499..31098
                     /locus_tag="LP468_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL2080473.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31113..31400
                     /locus_tag="LP468_000919"
     CDS             31113..31400
                     /locus_tag="LP468_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL2080474.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31449..32231
                     /locus_tag="LP468_000920"
     CDS             31449..32231
                     /locus_tag="LP468_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL2080475.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32252..32959
                     /locus_tag="LP468_000921"
     CDS             32252..32959
                     /locus_tag="LP468_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL2080476.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33221..36019
                     /gene="ileS"
                     /locus_tag="LP468_000922"
     CDS             33221..36019
                     /gene="ileS"
                     /locus_tag="LP468_000922"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL2080477.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36068..37594)
                     /locus_tag="LP468_000923"
     CDS             complement(36068..37594)
                     /locus_tag="LP468_000923"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL2080478.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37609..38256)
                     /locus_tag="LP468_000924"
     CDS             complement(37609..38256)
                     /locus_tag="LP468_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL2080479.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38440..38769)
                     /locus_tag="LP468_000925"
     CDS             complement(38440..38769)
                     /locus_tag="LP468_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL2080480.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38946..39674
                     /gene="sfsA"
                     /locus_tag="LP468_000926"
     CDS             38946..39674
                     /gene="sfsA"
                     /locus_tag="LP468_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL2080481.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39690..40703
                     /locus_tag="LP468_000927"
     CDS             39690..40703
                     /locus_tag="LP468_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2080482.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40703..41980
                     /locus_tag="LP468_000928"
     CDS             40703..41980
                     /locus_tag="LP468_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2080483.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42043..44745
                     /locus_tag="LP468_000929"
     CDS             42043..44745
                     /locus_tag="LP468_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2080484.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGASQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44897..45214
                     /locus_tag="LP468_000930"
     CDS             44897..45214
                     /locus_tag="LP468_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2080485.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45244..45564
                     /locus_tag="LP468_000931"
     CDS             45244..45564
                     /locus_tag="LP468_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2080486.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45672..47132
                     /locus_tag="LP468_000932"
     CDS             45672..47132
                     /locus_tag="LP468_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2080487.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47200..47421
                     /locus_tag="LP468_000933"
     CDS             47200..47421
                     /locus_tag="LP468_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080488.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47452..47634
                     /locus_tag="LP468_000934"
     CDS             47452..47634
                     /locus_tag="LP468_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL2080489.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47634..48047
                     /locus_tag="LP468_000935"
     CDS             47634..48047
                     /locus_tag="LP468_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL2080490.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48170..49351
                     /locus_tag="LP468_000936"
     CDS             48170..49351
                     /locus_tag="LP468_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080491.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49422..49586)
                     /locus_tag="LP468_000937"
     CDS             complement(49422..49586)
                     /locus_tag="LP468_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080492.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49740..49813
                     /locus_tag="LP468_000938"
     tRNA            49740..49813
                     /locus_tag="LP468_000938"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49774..49776,aa:Arg,seq:cct)
     gene            complement(49882..51021)
                     /locus_tag="LP468_000939"
     CDS             complement(49882..51021)
                     /locus_tag="LP468_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2080493.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51320..51955)
                     /locus_tag="LP468_000940"
     CDS             complement(51320..51955)
                     /locus_tag="LP468_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080494.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52068..52703)
                     /locus_tag="LP468_000941"
     CDS             complement(52068..52703)
                     /locus_tag="LP468_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBL2080495.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52737..53198)
                     /locus_tag="LP468_000942"
     CDS             complement(52737..53198)
                     /locus_tag="LP468_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBL2080496.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
BASE COUNT        17559 a         8993 c        11249 g        15423 t
ORIGIN      
        1 tttataaaaa taaaagttgt agtggaggct acgaagttta ctttgtcttt ttacacttaa
       61 tatttttttg ccaatttgga atcaggatgt tttgataact atcgttttca attgatggaa
      121 gctatattgt ttgctatcag tgaaataatt atatggtaaa cagtgttctt tttcttgttt
      181 ccattataaa aatcgtatcg ggatttttcg ttcttttaaa ttgaacattt ctatctatcc
      241 gcgtgttatc aacaaaacaa aatcaggtaa atagttgacg aaacagaaat aaatacatag
      301 tattatgttt tgaagcctaa gtacaatagt ctatagaaaa ggagcgatac cattggcaaa
      361 acgcattgac cgaatttata tgtatgtcaa agaaaaaacc gctcatttaa caaaggcaga
      421 atatgatcaa ggagtaacaa cacaggaaat tgctgaagtg ttagggattc agcgaacaaa
      481 tagcagtaaa gatctgaatc agctagtgcg cgaaggaaaa ctgataaaga cagacggacg
      541 accagtacgt tacatatatc aaacactcgt tacgcacgta aagccagtta caaaacatgt
      601 agtcagttac aaagaaacgc cggtctctga agaaaaaaat acactccaaa tagatactaa
      661 ggatatcttt gcaaaaatca ttggagctaa cggcagcatg aaaaattcag tggaacaggc
      721 aaaagctgcg attttgtatc cgccaagagg attaaattgt ttgattacag gacctaccgg
      781 atcaggaaag acttattttg cacacgcgat gtatcatttt gcaaaagcgc atcatgtaat
      841 agatgaggaa acggaactga ttgttttcaa ttgtgctgat tatgccaata accctgagct
      901 tttgatgagt catttatttg ggtacgcaaa aggtgctttt acaggcgcag atgaagaaaa
      961 aatggggatt atcgatcaag cggatggcgg tatgctgttt ttggatgaga ttcaccggtt
     1021 gccgcctgaa ggtcaagaaa tgatctttta ctttatggat catggaactt acagtcgtct
     1081 tggggaaaca acgaaatccc atgaagcaaa tgtacggatc gtaggtgcga ccacagaaga
     1141 cccaggttct tctctattag aaacttttgt tcggcgtatc ccaatcaata tcaaacttcc
     1201 ggcttttgaa aaacgtcctg caaatgagaa agtcgattta gtaaaaatca tgattgccca
     1261 cgaagcaaac cgcacgcagc gaaagatttc tttgacagaa gatgtagcaa aagcattgat
     1321 cggcagtgtg acctatggaa atataggaca attgaagtca aatatccagt tagtatgtgc
     1381 acgaggattt ctaaatcata tgcaatcacc cgaaatctcg atcacaatcg atgatttgac
     1441 agaagggatt cgtagcggat tgattcaatt agcaagcaac cgcagtgcaa tggcagagct
     1501 ttctaaaata ttggagccaa agataactgt agcaccaaat gatacgatca tgaaaatcca
     1561 atcggactcc tatgagttac cttataatct atatgatatc atcggagata aagcagcttt
     1621 actgaagtcg gatggtttgg atcaagaagc aatcaatcat ttcatttcta cagatatcaa
     1681 catccatctg aagtctttct ataaagacca tggtttttct tttaatgcag acagcaaatt
     1741 agcagaattt gtagatccga aaatcataga agtgaccaat cagatttatg taatggtcaa
     1801 aagatcttta ccatatgagt ttcagcaaaa ctttatttat gctatgagct tgcatatcag
     1861 ttcttttttg aaaaaaatca acttaggaga agaacggcat acgaatgata acatccgtga
     1921 gatggctttt gattttccag atgaatatgc tgttgcgaaa gaagtgcgta gttatatcga
     1981 aacgtatttt caagtggaga ttccagaaag tgaagactat tacttgaccg ttctactcgt
     2041 ctcgttacgg gcaaatcaag caagcggcag aatcggtgta gtcgttgcag ctcacggaaa
     2101 cagcacagca agcagtatgg tccaagttgt ccaacagttg ttagatgcag agaacgtacg
     2161 agcagtagac atgcctttgg atatggatcc gaaaacagca ttggaccgaa ttgaacgcaa
     2221 tgtacaagaa gtagatgaag gaagcggggt catactctta gtagatatgg ggtcccttgc
     2281 gtcgtttaat tcgcaaattc aaagagacac tggaattcca gtacgtactg ttgatatggt
     2341 aacaacttct ctagttttgg aaactgtacg aaaggtctca gtattaggga cagatctaga
     2401 tatgttgcat gaatcattga aaaattttcg aggttacgca gaaatatctt ctgtagaatc
     2461 tgttcaggaa gcaaaaccta ttcataagaa aaaagctgtt ttggctatct gcgcatctgg
     2521 cgaaggtaca gcacaaagaa tcaaagaatt gatcgaacga gcggtaaaca agcgtcaaga
     2581 aacagaatta gaagttctag ctttgtcgat tgtggaagtg aaagaagaac tgccagttat
     2641 ccaaaaagaa tatcagatca tagctactac tgggattact gatttgaata tccaagcccc
     2701 atttattcct ttagaacgtt ttattgatca aaatatcgaa gtcattttgg atcagttgct
     2761 gatggaatca gaattggagg aaactgaatt catctcccta gatgaagagt cagctaaaaa
     2821 tacgtgtgtt gagtttatct ctgataactt catctttatt aatggtagta agttaatcga
     2881 tccaatgtgg caattttcta cacaaatctc tcagacgacg ggaatcggcg atgaagaata
     2941 tggattcaaa atcaacctag tgatgcacac agcaggaatg atcgaacgta ttattcggaa
     3001 tgaaccattg actgtggaag aaaacgaatt gacaaataca acgaatgatc ctctttatag
     3061 ccaattggca gcctcagttg ttctgttgga agatcagata aaagtaaaag tgccgataga
     3121 agaaatgtat tatctgctac gtctagtcca taatcagtta gataaaaaag aatacactgt
     3181 gccatgaata cacaaaaacg atacactttt atagtgtatc gtttttgtgt attggttaag
     3241 aatcctttaa attcaattag tgtatcgtaa aaaagttggc acgctttttg cttatagtag
     3301 tgtgtgctag gaggtggttg ttcacacaga aatgataggg gtttctgtga agtagtgagg
     3361 aagaaggagt tttgcagatg gatattcgat tggcacgtat agatgatcgt ttaatccacg
     3421 ggcaagtcgc aacagtttgg tcgaagcaaa caggtgttga acgtatcatt gtgatcagcg
     3481 atgtagtcgc tcaagataaa ttgagaaagt ttctactaaa agaagctgca ccgccgggga
     3541 tcacagcaaa tgtaataacc gtgcagaaaa tgattcaaat ctatcatagt ggattattat
     3601 cacgagcaaa agtgatgctt ttattcacca atccccaaga tgttgaagcg gttgtccgct
     3661 gcggtgtaca gttgaagtcg ttgaatatcg gcggtatgag ttttactgaa ggcaaatcaa
     3721 tgattaccaa ttttgtttca gtaaatcaac aagatattga ttcctttcgt tacttgaaca
     3781 gtcaagaagt ggagttagag attcgaaaag tacctgctga caggaaaatc cttttgatgg
     3841 aactactagc gaaaatcaaa aaggtgtagc aagaatggtt gttggaaaag gtcaaataat
     3901 tctgttgtaa tggttagcaa ttattaatat ttttgaattt gttacaacaa aagtaaatag
     3961 gaggtataaa tatggtaggg attatcctag caagtcatgg acaatttgct gaaggaatct
     4021 tacaatccgg ttcaatgatc tttggcgaac aagaaaacgt caaagccgtg attttgaaac
     4081 caagtgaagg tccagatgac ttgagagcca aattggaaga agcggttgct tcttttgata
     4141 atcaagacga agtgttattc ttagttgatt tatggggcgg aacaccgttc aatcaatcaa
     4201 acacattatt cgaagagcac aaagataaat gggcaatcgt cagcggtttg aatttaccaa
     4261 tgttgattga agcctacgca tcacgctttt caatggaatc tgctcatgaa attgcagcac
     4321 acatcattga aacagcaaaa gacggtgtaa aagtaaaacc ggaagaatta gaaccggcag
     4381 aagcaccgaa agcagcagtt gaagacgcac aacctaaagg agcacttcca gaaggaactg
     4441 tggtcggaga cggaaaaatc aaatatgtat tagcacgtgt tgactcacgt ctgttacatg
     4501 gacaagttgc gacagcttgg acaaaagcag tgcaaccaaa ccgtattatc gttgtttcag
     4561 atgcagtatc aaaggatgat ctgcgtaaga gactaatcga acaagctgct cctccagatg
     4621 taaaagcaaa tgttattcct attagcaaaa tgatcgaagt agcaaaagac cctcgttttg
     4681 gaaataccaa agcattgctt ttatttgaaa atcctgaaga cgtattgaca gctgttgaag
     4741 gtggcgtaga catcaaagaa ttaaatgttg ggtcaatggc gcattcggtc ggtaaagtcg
     4801 ttgtaagtaa agtattgtct atgggacaag aagacgttga agcgtttgag aagcttgaac
     4861 aaaaaggtgt gaaattcgat gtacgtaaag tacctaatga ttcacgcgat aacatggatg
     4921 atattttgaa aaaagcaaaa gctgaattag caaaagcgta ataaataata ttaaaattta
     4981 taggaggctt atcatgtcta ttatttcaat aattttagtc gtattagttg cctttctagc
     5041 tggtatggaa ggtattcttg atgaatttca atttcatcaa ccactagtgg catgtacatt
     5101 gatcggttta gttaccggta acctcgaagc tggtatcgta cttggcggta cgcttcagat
     5161 gatcgcttta ggttgggcaa atatcggtgc cgctgtagca ccagatgctg cattagcatc
     5221 agtagcatca gcaattattt tagttttagg tggacaaggt gttaaaggtg ttccttctgc
     5281 gatcgcgatt gccgttcctt tggctgttgc agggttgttc ttaacaatga tcgtacgtac
     5341 aatcgctgtt ccaatcgttc atttgatgga tgcggctgct gaagaaggaa acatccgtaa
     5401 ggttgaaatg tggcacatca ttgctgtatg tttacaaggg gttcgtatcg cggtcccagc
     5461 agcagcgttg ctatttatcc cagcacaaac tgtgcaatca ttccttgaat caatgccagc
     5521 atggttaaca gatggtatgg ctatcggtgg gggaatggtc gtagctgtag gttacgcttt
     5581 ggtaatcaac atgatggcta caaaagaagt atggccattc ttcgttattg gtttcgttgt
     5641 agctgcaatt tctcaattaa cattgattgc tctaggtgct ttaggtgttg cattagctct
     5701 tatttacttg aacctttcta aaatgggtgg ttcatcaaat aatggaggcg gaagcaactc
     5761 tggtgaccct ttaggcgaca ttttgaatga ctattaatct tgaaggagga aaataaaatg
     5821 gcagaagaaa aaatcaaatt atcaaaaaaa gatcgtttag ctgttgcgtg gcgctctacc
     5881 ttcattcaag gttcatggaa ctacgaacgt atgcaaaacg gtggctgggc attttctatg
     5941 attccagcaa tcaaaaaatt atacaaaaca aaagaagaac gttctgcagc attaaaacgt
     6001 cacttggaat tctttaatac acacccatac attgcttctc caattttagg ggttacattg
     6061 gctctggaag aagaacgtgc gaatggcgcg cctgttgatg atgtagcgat tcaaggggtt
     6121 aaagtaggta tgatgggtcc tttagctggt gttggtgacc cagtgttctg gtttacagta
     6181 cgtccaatgc taggtgcact aggtgcttca ttagctatgg gaggaaatat ccttggacca
     6241 atcatcttct tcttaggttg gaacattatt cgttgggcat tcatgtggta tacacaagaa
     6301 tttggctaca aagctggttc taaaattact gatgaccttt ctggcggatt gttacaagac
     6361 gtaacaaaag gtgcttcaat tttagggatg ttcgtattag ctgcccttgt acaaagatgg
     6421 gtatcaatca aattcttacc agttgtatca actgtaaaat tagataaagg tgcttacatc
     6481 gaatgggata aattgccttc aggtggtgaa ggaatcaaga gtgcatttga acaagttaat
     6541 aatggcttag ccctttctcc tgaaaaggta acaacattac aagacaactt agaccaattg
     6601 attcctggtt tagctgcatt aggattaaca ttgttatgta tgtggttgct taagaaaaag
     6661 gtttctccaa tcgttatcat ccttggttta ttcgtagtcg gtgttgttgg acacgtcatc
     6721 ggacttttat aatccataaa aatatagctc gggcgttgtc ccgagctttt tttatatagt
     6781 atactgttca taaacaaata tctggaggga gaaaatggtt caatcaatca atacaaaagt
     6841 agacttggta attgatgcta cttcgtttac gggtctgaca gattacgggc aaatcatgat
     6901 aggtgataat ggttttgagt tttaccatgc gcgagataga cgcaaatata tccaaattcc
     6961 atgggaagaa gtggattatg tactagcatc agtcatgcta aagggaaaat ggattcctcg
     7021 atatgccatt caaacgaaaa aaaatggtac atacacattt tcttccaaag aacctaaaaa
     7081 agtgcttcgt gcgatcagag aatatgtaga tgaagataga atggtacaat cattgagttt
     7141 ctttgatgta gtgaaacgtg gtattcgtag tatgtttaaa cgcaagtaaa aaataaagaa
     7201 aacttctaag aggaggtttt ctttattttt ttactttgca gaagaaaata tgaaatagca
     7261 aaaccaatta tttgtcccct ttaaatccca tatgctaaaa ttgattagca aagaaggagg
     7321 ttatattatg agttggttat ggacattgat tgttggagcc gtgatcggag caattgcagg
     7381 tgcgatcacc agtaaaggaa attcgatggg ctgtgtaacg aatatcattg ctggactagt
     7441 cggttcaagt attggacaag cgattttcgg cgaatgggga ccaaaagctg caggtatggc
     7501 acttattcca tctattttag gcgcagtgat tttggtagca gttgtctcat ttttctttgg
     7561 aaaacgatca taagttttta caaaatagta aactaaaagg agttgcagcg agactgtgac
     7621 tcctttttgg ctttatttat ttaaaataaa aagaagtttt ccggaaattt ttatttaact
     7681 gtcgtgtacg aagaaaagtt tgctataatg gaaaaaagcg tgcaaagaaa gagggagttt
     7741 cattatgatg ctacgtgtag aaaaattgcg caaaaaaatg caagaagaaa atttggattc
     7801 atttttggtt accagtccgt acaatcttcg ttacttaacg aactttacag gtacgacagg
     7861 attagctgtt attactttgg aaaaagcatt ttttattact gattttcgtt ataccgagca
     7921 ggcggcagcg caggctcaag ggtttgaaat tattaaaaat gtcggaccta tttttgatga
     7981 ggtagcaaac ttagtacgca aagaagaact gcactcatta gcttttgagg aaacaacagt
     8041 ctcattttta gaatattcgg ttttagaaga aatcatcgat gcggaattag tacctgtttc
     8101 acagatgatc gaagaactca gagaagtgaa agatgaagaa gaaatcgcta ttatcgaaaa
     8161 agcatgtcat attgcggata tggcatatga tcacatcctg aaaatgatcc aaccgggcat
     8221 gactgagatt gaagtcgcaa atcaactaga cttttatatg cgttctcttg gcgcttcagg
     8281 tgtttctttt gatacgatcg ttgctagcgg attgcgttcg gctatgccgc atggtgtagc
     8341 aagcaaaaaa atcatcgaac aaggtgactt gatcacattg gactttggtt gctattacga
     8401 agggtacgtt tccgatatga cacgtacatt cgctattggt gatcctgggg aaaaattaaa
     8461 agaaatttat caaatagtct tagatgctca attagcagtt attgatgctg caaaaccagg
     8521 aatgactggt gtccaattag atgcagttgc tagagattat atttcaaaac atggttacgg
     8581 ggaagcattt ggacattcta caggacatgg gatcggttta gagatccacg aaggaccaaa
     8641 cgtttcttct cgtgcagaaa agcaatttgt accaggaaat gtgatcactg atgaaccagg
     8701 gatctactta ccaggaatcg gtggagtacg tattgaggat gacttgttga tcacagaaga
     8761 tggaaatcgt gtgttgactc gttcaccaaa agaattgatc atcttatagt ttcatcaata
     8821 gaagaagtaa gcgtaaaaat cagtgttcac agactttgtt atagaaaatc actcgattta
     8881 atgatacact atagaagaac ttttaagctg taagagataa taaagttggg tgttttctcc
     8941 aattcatagc agtttgcagc tgatcggcgg cagttttctt accacgtgat cactatgccg
     9001 catcatagag aattcggatg tatctcgtgc ttaggcaaag ggaggaataa ataaatggca
     9061 gatgaaaaaa atttgatttt aaacgcaaac caagatttag gagagatcgt gatcgctcct
     9121 gaagtcatcg aagtaattat cgggattgca gcttctaaag tagaaggcgt atacggaatg
     9181 cgcggaactt ttgccagcaa tgtcactgaa ttattaggac gtgcagctca cggaaaaggt
     9241 gtttacttag caaacgagga agatggcttg aaagtagatc tttactgtta tctagaatat
     9301 ggtgtttcag ttcctaaagt agcaatggaa atgcaggaac gggtcagcca gcaagtcctt
     9361 ttcatgacgg atatcgattt atctgaagtc aatatccatg tagtagctgt tgttcctgaa
     9421 aaattagaac aaccaacaat cgaagaactt tttgaagacg aagaggaaga gaatgaataa
     9481 agaattatca agacacgaga ttcgggaaat ggcattgcag gctttatttc cattagactt
     9541 caatgcagac ctaacaaaag aagatgcgat tttcaacgca atcgaattag accaccgcga
     9601 catgatcaac gaagatgaat cagagtttgt tcctgtttat cttgatacgc tagttggcgg
     9661 tgtctgtgca aaaaaagatg aattggataa agtgattgaa aaacatttaa aaaacaattg
     9721 gcacatcaat cggatctcaa aaatggattt ggtgatcttg cgtatcgcga tttttgaaat
     9781 gacttatgtg acagatgtac cagcggctgt tgctttaaat gaagcaatcg agttggcaaa
     9841 aacatttagt gatgaccgtt cacgtaaatt cgtcaacggt gttttatcca atgtattgaa
     9901 agaattagaa gctggggcgt aagtcctagc ttttttctat gaatcatcat aaacctgtta
     9961 taaatcggga aaattctatg gtagaatgaa aacacaaaaa atatctggga gtggttagat
    10021 ggcagaattg attaacggaa aagaattagc tgaaaaaatg caggcagaga ttgctgaaaa
    10081 aatccaaaaa ttgaaagata atggtatcca tcccggatta gtcgttttat tggtagggga
    10141 aaatccagcc agccaaatct atgtaagaaa taaagaacgt gtagcaaaag aaatcggaat
    10201 ccattcattg gtagagcgtt atcctgagac gatttctgaa gacgaactac ttgcagaaat
    10261 tgaaaaatac aatcaagatc ctagttttca tggtatattg gtccaattac cattgccaaa
    10321 gcatatagat gaagaaaaga tcctgttagc tatccgccct gaaaaagacg tagacggttt
    10381 tcatccgatg aatttaggca gactccttgc gggtaaaccg gacaagattc cttgtactcc
    10441 atacggcatc atgaaaatgt ttgaagctta ttctatcgat ccggcgggta aacgagcagt
    10501 agttatcgga cgaagcaata tcgtcggtaa accgatggct cagctactct tgatggcaga
    10561 tgcaactgtt actgttgctc attctaaaac cgaaaatctg gctgaactgg cacaagaagc
    10621 agatatttta gtcgtagcaa taggacgtgg acattttgtc acaaaagaat tcgtaaaacc
    10681 aggtgctgta gtgatagatg tagggatgaa tcgtgatgct aacggtaagc tgatcggtga
    10741 tgtgaaattt gatgaagtgg agcctattgc aggctggatc actcctgtgc caaagggtgt
    10801 agggccaatg actatcacga tgctgatgta tcaaaccgta aaatctgccg aagcttttgg
    10861 agcaggtgaa tagatggcac aagaatattt aactgtcact acattaacga agtatttgaa
    10921 aagaaaattt gatgccgatc cttatttaga acgcgtatat ttaacaggcg aaatatcgaa
    10981 tttccgttta cgtgccaatg cccatcaata tttcagctta aaagatgacc atgcaaaaat
    11041 atctgctatt atgttcaaag gagcattcca aaaattacga ttccagccaa aagaaggaat
    11101 gaaagtcctt gtcgttgggc gtatttcatt atatgaagcg ggaggttctt atcaaatcta
    11161 tgtagagcac atggagcctg atggaatagg tgctttatat caagaattgg aagaacgaaa
    11221 agaaaagctg atgaaggaag gcctttttca agggcctaaa aaaatgctgc cacgtttccc
    11281 aaagcgaatc gcggtcctta ccagtccaag cggagcggtt atccgcgata tcatcacgac
    11341 ggtgaaaaga agatatccaa ttgtccaatt ggttttgttc ccaacagttg tacaaggaaa
    11401 ccaagcagcg gacaatgttg tcaggaatat ccagagagta gaagagatgg gcaatttcga
    11461 tacaatgatc atcggtcgtg ggggtggttc gattgaggat ttatggccgt ttaatgaaga
    11521 gcgggttgct cgggcgattt atcaagctaa tacgccggtg atttcatctg taggacatga
    11581 aacagatacc acgatcgctg atttagtagc agatgttcgg gctgccactc caacagcagc
    11641 tgcagaatta gctgttcctg ttttgtcaga agagttgatg cgcattcaag aacggcaagc
    11701 tagattgcag caggcgtttg tacgccagat ccagcgcaaa caagaacggt tcgagcgtgc
    11761 tcgacgttcc tatgtatttc ggcagcctga aagattgtat gaaggtcaga ccatcaaatt
    11821 agaccagttg aaacagcgat tatatcaagc tacacagcaa atttatcatg cgaaagaaaa
    11881 acaaacgatc gcattaagcc accaattgga acaagtggct ccgctttatc gagttaaagc
    11941 agctcgccaa gaaactgctt atctagaaaa acgcttagaa gagaaaatcc aacaatatat
    12001 gaaacaacag cagcagcgtt ttgctcaagc tgttcaatct cttgatttgt tgagtccatt
    12061 gaaaatcatg ggaagaggct acagctatac gacgttaaat gatcaagtag taaaaagtgt
    12121 caccgagatt catcaagggg atttgctgac gatccattat caagatggaa tcgttaaagg
    12181 acaagtacaa gagatagaca aaggagaata aaaatatgga aaatccaact tttgaagagt
    12241 cactgcaaga attagaaaaa attgtcatgc agttagaaca aggagacgtt ccattagaat
    12301 cagctctaga ttcgtttaaa cgaggaatgg aattaagcaa acattgccaa gatacattag
    12361 ctaaagcaga agagaccttg acgaaaatga tgacagaatc aaatgaagaa gttgattttg
    12421 acggaaacga ggaaagctga gatgagatta actgactttt cagctattca tctacctgct
    12481 gtagaaaaag aaatcttgtc ttttttagat gagcatacaa cggatagagg actctatgat
    12541 gcgatgagtt attcagtgaa agcaggcggg aaaagaatac gtcccttatt acttttaacg
    12601 gccgttgctt cctttgatga gcctattgat gttcccgtct atcaagtagc agctgcttta
    12661 gaaatggtgc atacgtattc cttgatccac gatgatttgc ctgcgatgga caatgatgat
    12721 cttcgtagag gaaaacctac caatcataaa gtattcggcg aagcattagc tatattggcc
    12781 ggagatggtt tgcttacagg agcattccag ctaatcagta tggcacactt aggtaattct
    12841 cctaagcttc tgctgcttca gcaattagct gtttgtgcgg gatcacaagg tatggttgct
    12901 gggcaagctg cagatatcga gggcgaatcg aaaaagcttt ctttagaaga attagcattt
    12961 attcatgaaa gaaagacagg gcatttgatt cgttatgcct tgctggctgg tggcatatta
    13021 gcgaagcaac ctgaagaaat cttattgcta cttcaacgat tagccgaaca tttaggttta
    13081 gcttttcaga taagagatga tctactcgat gtgattggta caacgaaaac attagggaaa
    13141 acagctggta aagatgaacg tatggaaaaa aatacttacc cgcgtttatt aggcctagaa
    13201 aagacacgtg aggcgttgga gattgagctg ttatccgcca acaagatcat agacaaatta
    13261 gaagaggacg ttttttcttt tgatggcggg ctgatgcgcc agatgatcaa gcaatttgat
    13321 gtggagaaat gagggaaaga atggaaaaag aacgcgtaga tgtattagcg gtcaaacaag
    13381 gattatttga aacaagagaa caagccaaac gttcagtgat ggctggtttg atttacaacg
    13441 aaaaaaacga gcggtttgat aaaccgggag aaaaaattcc agtgagtagt gaattaagag
    13501 tcaaaggtaa aaaacttcct tatgtttctc gagggggatt aaaattagaa aaagcactca
    13561 aagcatttga tctatctgtt gaaggaaaaa cattgttaga tattggtgca tccactggcg
    13621 gatttactga tgcagctttg caaaatggcg caaaaatgag ttatgcttta gacgttggct
    13681 acaatcagct agcttggaaa ataagacaag atcctagagt cgtcgtaatg gaaagagtga
    13741 attttcgtta tgcaaaaccc gaagacttta ccttaggaat tccagaagtt gctgttatcg
    13801 atgtttcttt tatttcacta aaactgatgc tgcctccatt acatgctatt ttaaaagaag
    13861 agggagaagt gattgcttta atcaaacccc aattcgaagc aggcagagaa gctgtaggga
    13921 aaaacggaat tgttcgtgac cctcagaccc atcaaaaagt tttagaagac attttgtcat
    13981 ttgcggcaca aggtggatat gatgtgctgg aattaagtta ttctccgatc acggggggag
    14041 aaggaaatat cgagttcttg gctcacttga ggaaagtacc cgaaagcgga acaatcaatt
    14101 cagctattaa tatggcagaa gtggtttcaa atgcacacga acagtttgac cataaataaa
    14161 ttgtaactgt gaaaatcaag tgagaagtat gcggattctt ctttattata ccaaggaaat
    14221 aagctatcat tgattaagaa gaatatgcta aggagcgaag acgtaatgag aaaaaaagat
    14281 cggcatcgtt tgattactcg attgttgagt gagcaagata tccgaaagca ggaagaattt
    14341 gttgaaatcc tgaaaagcaa aggaatatct gttactcaag ctacgatttc cagagatata
    14401 aaggaactga aactgatcaa ggtaccggct tcagatggcg gctaccgtta tagcatacca
    14461 gctgaaacaa acgaagatgt aaatactaaa ttggaaaaac tattaaaaga cgctttcgtg
    14521 gcagttgacc aaatggaaaa atttgttatt ttgaaaacat tgccgggaaa tgcttcggca
    14581 gcagcaaatt tgattgataa acgttacaag aaagaattat tttcgattat caatgatgac
    14641 gataatgttt tgatgattac acgaactgaa gaccaggcag ttttattgaa gaaagacttc
    14701 ctgcattacc tttaagttga ggagcgaatg tgatgctaca agaaatcagt attactaact
    14761 ttgcgattat tccggaattg cggctttctt ttcacgaagg aatgaccgcg ctgaccggag
    14821 agactggtgc gggtaaatcc attattatcg atgctttagg tctgttagca ggaggaagag
    14881 gttcaagcga ttatatacgt caaggagcag aaaaatgtgt gcttgaaggg ttgtttgaac
    14941 taccaaaaca agaaggattc tctgaactga tggttgaatt agggatcgaa acagatgagg
    15001 acaatctgat tgttcgacgg gatatgtcct taactggaaa aaatgtttgt cgagtgaatg
    15061 gtcatattat cacattagct aatctgagaa gaatcggcag ttatttagta gatatccaag
    15121 gacaaaacga acatcaggaa ctgctccagc ctgaatcaca tcttgcttta ttggatcgtt
    15181 ttggagatgt agctttccaa cagaagaaaa agagttatca gcaagaatat atctcttatc
    15241 gtgagctgga aaaaagggta cgaaaagtgc agcaaaatga aaaatcctat gttcagagaa
    15301 tagatatgct ccatttccag caagaagaaa tagctgctgc tgatttgcaa gtcggagaag
    15361 aagagaaatt aaaagaagaa agagaaaaac ttagcaatta tcaaaaaatt gctgatggat
    15421 tagctgcagg ttacggagca ctgacgaata atgaacaaaa cagtgtagat ggtgttggct
    15481 tggccgtttc agaactgcaa gggatcgccc atctagatgt ggagtatgaa gcaatttatg
    15541 aaaatatcca aagtgcttac tatttgctgc aagatgcaat cggcgatatg agtcgtcaga
    15601 ttgatttatt ggagttagat gagagtcgtt tagaagaagt tacgcaacgt ttagaattaa
    15661 tccgacagtt gaaacgtaaa tacggcgaat ccattgagtc aatattggct tactatgacg
    15721 aaatcaccga agagctagct tcttctgatt tttcagaagg tcaattggac aaaatgaaag
    15781 aggaactaga gcaaaaagag cttctacttc agcaacaagc cgcagatctt catgaagcgc
    15841 gtaaaaaaat cgcaaaagaa ttggaaaaat ccattctgca tgaattgaaa agtctgtata
    15901 tggaaaacac tgagtttgag gtacgtttct taaaagaaga aaatagacaa ttgaatcatg
    15961 atggatttga ccaaatcgaa ttttacatta cgaccaatcc aggagagcca ctgaagcctt
    16021 tggtgaaagt cgcttctggt ggcgaactgt ctcggatgtt gcttgctttg aaaactattt
    16081 tttcttctga gcaaggtgtg acaagtatta tttttgatga agtggataca ggtgtgagcg
    16141 gaagagttgc acaggccatc gcagataaaa tttctcaaat atcgaaatac tctcaagttt
    16201 tgtgcatcac tcatctgcct caagttgctg cagtcgccga ctatcaatat tatattgtga
    16261 aagcagtgat tgatggacgt acgcaaactt ctgtttcaga gttgaaaaca aaagaaagag
    16321 aagaagaaat tgcacgtatg ctggctggaa gtgagattac aaaactcaca ctcgaacatg
    16381 caaaagaact attgaaactc gcaaaaagga cctgagccac ctcgcagtgg ttcaggtcct
    16441 tttcagcagc tgatagctat attttatttt tacatgacac tcattacagc agtcaataca
    16501 acagatccaa tcgttaaaat cagcattgtc caaatgacaa attttgttac tttagcaaaa
    16561 gtacttgttt gttttttttc acgcattgtt ttcaacctcg tcattaatta gttgattcaa
    16621 gtgtacaatc ttttttccat ttccacaaga gggctttttt ataaaaactt cccttttttt
    16681 aaataatagg tagttacgat acaaataaat aatgttaata gaactagcca tataaaggca
    16741 tcatcccttt cagcaatagg taacttaatg ttcattccat agatactgcc gacgattgtc
    16801 ggtatagtta aaataatcgt taaagaagtt aaaattttca taatattatt cagattattc
    16861 gatacgattg ctgaaaaagt ctgattcatt tgttctacta gttttaattg aatgcgagaa
    16921 gtagtcattg cctgctctgt ttccaccaat acatcacgta aatgattttt caaagcatga
    16981 ttttcttgga aaagtttatt ttgcgctagt tctttcaatg catctaaatt agcagaagtc
    17041 gcttctctga aataaacgag gcttttttgg atatccatga tttgataaag ttgtttgttt
    17101 tcagtggata cttgaagttt ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa
    17161 taactgttgt aagagagtgt gacctgccaa atgaattgaa agaagatatt gagattaggc
    17221 gaaatatcac tttttggaaa ggtctggcta aagactttct ttaaaaacag tggttcatga
    17281 ttcgtaattg tgataagctt ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc
    17341 acttgaaaat aaccgctagg acttgtttta gcaaaaggat attgtaacaa taataacgct
    17401 ggctttgtca actttgattg attgaattct tctgtacggg aattttctgc atcgtccaat
    17461 atggaagtga tgtaatctga cggaatttca aattgatgtg tcagctgatg aatctcttct
    17521 tgattaggac gttctacaca ataccagatc gtttggtcag tttcctttcc ggtattacgc
    17581 agtttctcat tatctaatgt aaaatatttg atcatgattt tcctcctgtt gcctgtttct
    17641 tttattataa cggataggga attggaatac atggaatgtg tttgtaagat atagaatata
    17701 actgcataaa tttaaataaa atgaaacagt tgtgtaaagt atatacagta tacttgaagc
    17761 aacgataaaa aaggagttta cgttcatggg cacattcaca ccacttatct tgttttggta
    17821 tatttacccg gtaatcgttt tgtttggttg ccaatttctt gtaaaattat tttcgttaaa
    17881 tcgtcgtttt aaaataaaag cccctgattt ggcgattcct tttttgtggg gcggtatgca
    17941 tgcattgtct agaaatacag ggacaatttc tatcttaccg tttttcttta tttctgtttt
    18001 gctaatggga atttgtattg ctgttttcca agcatattat tatgaagaaa ttatttatcc
    18061 gcgttatttc aagatgactt ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt
    18121 cttgatcatt gtgaacatac tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc
    18181 ttttaaaagg ctttttgcag cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt
    18241 tcccggattt cccagaaaag gtggtagaaa gtgggggatt gtggtagact aattttagtt
    18301 agtggaggaa tggggggctt tcaatgttga tgggtgaatt ccaacataat attgatgcaa
    18361 aaggacgttt aatcgtgccc tcaaaacttc gtgaagaact tggcgaaaag tttgttctga
    18421 cacgcggatt ggatggctgt cttttcggct atccgatgag cgaatgggaa aatctggaag
    18481 ctaaactgaa cgaaatgccg ttggctaaaa aagacgcacg tacttttgtg cgattcttct
    18541 attcggctgc cactgaatgc gaacttgata aacaaggacg aatcaatata cccagcacgt
    18601 taagaaatta tgcagctttg acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg
    18661 aaatttggga tgagacacga tggcaagatt tttctgcagc agcagaagag aactttgacg
    18721 aaattgctga aagtatgatt gatttcggac tataagaata ggaagaggct gactaatgac
    18781 tgaaacattt caacactata cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa
    18841 accggatggc gtttatgtag actgtacact cggcggtgcc ggacatagtg aatatttatt
    18901 aagccaacta agttctaaag ggcatctgta tgcgtttgac caagatcaaa aagcaatcga
    18961 tcacgccaag ctgcgtttag cttcttatgt cgaacaaggt atggtcacat ttatcaaagc
    19021 gaacttcaga gaattagaag aacgcttgag tgagcatgta gataaggtag acggcatttt
    19081 gtatgatcta ggggtttcct ctcctcagct agatgaagca gaacgtggat ttagttatca
    19141 tcaagatgca ccgttggata tgcgcatgga tcagtcagct cctttatccg cttatcacgt
    19201 aattaatgaa tattcctacc atgaattagt aaagattttc ttccgctatg gcgaggagaa
    19261 attttccaaa caaattgctc gtgaaatcga acgagtacga aaaacaaaac caatccaaac
    19321 aactggtgag cttgtcgaaa tcattaaaca agtcatccca gctcccgcaa gaagaaaagg
    19381 cgggcatcct gcaaaaagaa tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg
    19441 tgccgaagag gcctctttag aacaggcaat ccggttattg aaagtcaatg gaagaatcag
    19501 cgtaatcaca ttccattcat tggaagacag aattgtcaaa agtatgttta aagaatatag
    19561 tacggtacaa gatctaccac cgggacttcc tgtcatacct gacgaattcc aaccagaact
    19621 gaaagtcatt actcgtaaac caatccttcc ttcagaggaa gagctaacag aaaacaatcg
    19681 atcacgcagt gcaaagttac gtattgcaga aaaaataaga atgaaagagg agtagaatga
    19741 tggcagaatt aaagaaaatg caagattacg aatatgattt acctgaattg gtggatcagc
    19801 cggaacaaca aatgcctgat tcttcttcga atcaagaaat cattcttcca caatcaccgg
    19861 caaaacgatt aaagcagatt tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg
    19921 ctattgttgc tttatgtgtt ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa
    19981 aagaaatcac gtcaatacaa acagaaatca atgataaaaa gcaagaaaaa acgagtttag
    20041 aacaagaaaa aaacgaactt tctcgtactg aacggattaa acaaatcgca gaagaaaaag
    20101 gattgtctat taatgacgac aatttaagga aagtgaagta aatgagtctt aaaaataaaa
    20161 ttcggcggtt tatggaaaag aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta
    20221 tcattttatt tgctacgagt attggattgt tctttttatt tgccgtccgt ttctcgtata
    20281 tcgttattgg aggtcatgtt gctggtacct cattagctga aaaaacaaaa cagttgtacc
    20341 aaggaagtga agtagtaaaa gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc
    20401 tcgcagaaga tgcctcctct tattcaatta aagcgatact ctcaaaaaca tatacctctg
    20461 gggataaaaa actgtatgtt gaagaaaaga attttgataa aatagcagaa atcctgcata
    20521 agaatctttc tatagacaaa aaagatgcac tgaatatttt agaggacggc gcaaaaaaag
    20581 agctgtatca agttgaattt ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa
    20641 acatcgaagc ggacatgaaa aaagaaggtg tcgctggtct ttattttgtc gaccatcagg
    20701 ctcggatgta tccaaatggc gtcttttctt ctcattttat tggatacgca gttccagaca
    20761 aagatgagaa tggcttagtt ggtaaactag gtttggagtc tgcttacaat gatatcttga
    20821 gcggtaaaga tggtaagatt atttatcaaa aagataattt tcaaaatcct ctgccaggta
    20881 cagtggcaga agaagaaaaa gctgtcgacg gacaagatat ctacacgact ttagacagca
    20941 gactacaaag ttatttagaa acactgatgg atcaagtaaa tgaagaatat cagccagaag
    21001 aattgacagc agtcctgatg aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac
    21061 ctactttcaa tcctgaaaca atggaaggat tgactggaaa agatgctatc tggcgtaatt
    21121 tcttggtaca agatagttat gaaccaggat caaccatgaa agttttcact actgcagctg
    21181 ctatcgaaga aggagaattc aacgagaatg aaaccttcca atctggaaaa atccaagtag
    21241 aagatgctac gatcaatgac catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag
    21301 ctctttcatg gtcaagtaac gtcgggatgg tcatactgga acagcgatta ggcggacgat
    21361 ggtataacta tttacaaaaa ctgggatttg gacaaagtac tcattctgga ttagatgatg
    21421 aagtaaacgg tgctttacct acattaaata ttgtcgaccg agcaatgagt gcttatggac
    21481 aagcggtagg tgtgacgaat ttccaaatga tgaaagcttt cacttctatt gcgaataacg
    21541 gtacaatgat tcaacctcga tatatcagca aagtggtgga tccccaaact ggagaagagc
    21601 gaacaactca aacagaagtt ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc
    21661 gtgaatatat gagagatgtt gtcgaaagcg aaaactacgg tagtgtttat ggtgtatata
    21721 gtgtacctgg atacaatgta tcggcaaaaa ccggaacagc ccaaatcgct tctgatacag
    21781 ggggatatca aacaggagat acagcctacc tgtattcgat tgtggagatg gttccttctg
    21841 aagatccaga ctatgtcttg tatctaacaa tgaaacaccc taagacatat gatcgaatgg
    21901 cattggctaa aatcgcaaat ccattgatga aacgggcaat ggattttaaa gaaactgaag
    21961 aagattcaga tacagaaaca aaaacagaaa aagtatccgt agccgattat cgtaatcttg
    22021 aagcggacgt tgcagcagct gatgctcaaa aaagtggact gcaacctgta gtgatcggta
    22081 atggtaaaaa agtacaaaaa caatctactg ccaacggtga tcagttgatc tctggagaaa
    22141 aactgatcct atatactggt ggtgataagc tgatgcctga cgtaacagga tggtcaaaag
    22201 cagatatcat gaagctgggg aaaatcctcg gtattgaagt tagttttgat ggagatggtt
    22261 attgtgtcaa acaagaactt gctccatatg aaaaaatcac tgaagacaaa cttagtttta
    22321 ctttagaaga ataagaagag aaataggaga gaaaagagca tggaatggac acaagcattg
    22381 attcccattg tcagcagttg tgcaatgaca attgccgcaa tgccgctatt tattggttat
    22441 tttcaaatga aaaagcaagg tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc
    22501 aaagccggaa ctcctacaat gggcggctta gtgtttctga tcggctctat tttgacagga
    22561 atttgggttg gagcttggca aaaacagcta actcctactc ttttcatctt gctttttgta
    22621 ttagcgttat acggagtaat cggctttctt gatgatttta taaaaatatt caagaaaaga
    22681 aacatgggac tgaactcgaa gcagaaattg attggacaga ttctaggggg aatcatcttt
    22741 tatcttgttt accgttctga aggttatcca ggtgtattga atttcttcgg actagatcta
    22801 cctttaggaa tcatttatgg tattttcgct ctcttctggc ttgttggatt ttcaaatgca
    22861 gtaaatctga cagatggcat cgatggatta gttgctggct taggaagtat ctcttttgca
    22921 gcttacggtc taattgcttg gcatcagcat cagtatgatg tattaatcat ttgcttaagt
    22981 gttttaggag gtttactggg tttcttcgtc tacaacagaa aacctgccaa gatttttatg
    23041 ggagatgtcg gttcattagc gttgggcgga cttttagcgg caatttctat aatgctaaac
    23101 caagaatgga cattgctttt gattggtttg atctatgtta tggaaacagc aagtgtgatg
    23161 cttcaagtta cttcctttaa gcttacagga aaacgaattt ttaaaatgtc tccaattcat
    23221 catcactttg aaatgtgcgg atggtcggag tggaagattg atacagtttt ttggttgatc
    23281 agcattgtga cttcgttgat cacattatgg atcgtttggt aggagatgac gggaaatgaa
    23341 aaaaatatca acatatgaaa ataagaaagt gcttgtctta ggactcgcaa aaagcggagt
    23401 aagtgcggcc aaattattac atgaattggg cgcacttgtc accgttaatg atggaaaacc
    23461 ttttgacgaa aatccggaag cacaagagct gctttcttta gggataaaag taataacagg
    23521 tagtcatcca atcgaattgt tggatgaaga attttcattg atggtcaaaa atccagggat
    23581 tccctacagt catcctttag tagcaaaagc ccaagaaatg ggtattccgg taattacgga
    23641 agttgagcta gcttacgaag tagcggaatg cccaattatt gggattacag gaacgaacgg
    23701 aaaaacaacg acaacaacga tgacaggact actactgaat gcaggagcag atcaaggaat
    23761 tgcacgttta gcgggtaata ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc
    23821 agaagataaa attgtgatgg aattgtctag cttccaactc atgggaatca cagatttccg
    23881 ccctcatata gcggtgatta ccaatatcta tgaagcacat attgattatc atggtacaag
    23941 aaaagaatat gtcaaagcta aatggaacct tcaaaaaaac atgacagaaa aagattatct
    24001 gatccttaac tggaatcagt cagaactaca agaattagcg caaagaacaa aagcacgcgt
    24061 actgcctttc tcgacaaaag aagtgttgga agacggtgtg tatgctgacg attactcaat
    24121 atactataaa aaagaaaaaa taatggaaat atctgaactt ggcgtaccag gtaagcataa
    24181 tgtagaaaat gcactagctg ctatttctgt agcaaaattg tatggtatat caaatgaagc
    24241 tatacgagaa acgttgcatt ttttccatgg cgtaccacat cgtacgcaat atgtaggaga
    24301 aatccaaggc agaaaatttt ataatgattc aaaagcaacc aatattttag cgactaaaat
    24361 ggctctaagt ggatttgaaa cgtctaaggt cgtgttattg gctggcggat tagacagagg
    24421 aaatacattt gatgaattaa ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg
    24481 ccaaacaaaa gaaaagttga tggatgctgg aaaaaaagca ggcatcgaga caatagtaac
    24541 agccgattct gtagaacaag cagttccttt agcattagaa aacagtacag atggtgatgt
    24601 agttttatta tcaccagcga atgccagctg ggatcaatac ccaaattttg aaactagagg
    24661 aaacagattc atggaagctg tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa
    24721 aaatgaaaat tttggttaca ggcggaggaa cagggggaca tatttatcca gctcttgcct
    24781 ttgtcaatta tgtaaagact caagaaccga atgctgaatt catgtatgtg ggagcaaaac
    24841 gaggtctaga aaacaaaatc gtccctgata caggaatgcc tttccatacc ttggagattc
    24901 aaggatttaa acgaaaaatt tccatgcata acatcaagac ggtccgattg tttcttaaga
    24961 gtatccgtca agcaaaaaaa atcctcagtg attttcaacc agatatcgtt atcggtactg
    25021 gaggatatgt ttccggagcg gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta
    25081 tccatgaaca aaacagtgta ccaggtgtta ccaataaatt tttaagccga tatgtggatc
    25141 ggatcgctct ttcatttaaa gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg
    25201 taggtaatcc tcgagcacaa gaagtagcag atactaaaaa atcagatatt ttgaaaacat
    25261 ttgatttgga tccagaaaag aaaacagtct tgatttttgg cggtagtcaa ggagcactta
    25321 aaatcaatca agcagtatca gtttttttaa gtgaatatat tccttcttct taccaagttt
    25381 tgtatgcttc aggagataga tattatgaag agatcctaaa taaaataaat cctgaaatac
    25441 aaaatattag tgtccagcct tatatcaaaa atatggcaga ggtcatggct tccagtgatc
    25501 tgctggtggg gcgtgctggt gcaacttcga tcgcagaatt cacagctctg gggttaccgg
    25561 cagtgttggt tcccagccca tatgttacga atgatcatca gactaaaaat gcaatgagtc
    25621 ttgttcacgc aggagcagca aaaatgattg cagataatga actaacaggt gaatcactaa
    25681 gtcagacagt caacgaaatc atgggtgatg aagaattgca aaagcaaatg tgccgagctt
    25741 ctaaagaaca aggaatccct gatgcttcaa aacgtcttta tgacttagta aaacaaataa
    25801 tcaaaaaata aaggcggtgg tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca
    25861 tccgtcttct gatgaaaaca atttgactcc ttggcaaaag gctaaccgaa aatatctggc
    25921 agaacaagag atgaaaaacc aagagccaaa aaaagaagac ataacattag atacacccct
    25981 ttcagattct gaagaagaaa aaacggttca agaggaacag caagaagaaa gccagtccga
    26041 gaaaaaaatc gaattttttg aagagatcaa gcaaaagaaa aacggtggac catataacgg
    26101 ttcttttttg aaccggctgc ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg
    26161 gttagctttg atcatcactg tattgggtat accgctgatt tttttgatct attatgtttc
    26221 tccttatagc aaattacaag cagttgcagt atcaggcaat aagacagtca acagccaaga
    26281 aatcatctct gatacaaaat tgtcattagg agaaaatgtt tggggacagt attttcatcg
    26341 atctacttat atcgatcgcc ttaaaaaagc acagccaaga atcgaaacag caaatataca
    26401 tttcaaaggg atgaatgaat tcgatttgga tgtaacagaa tataaagaga ttgctttgat
    26461 cgcaaaaaac aatcaatact acccagtgat tgaaaatgga acagtattag atgaaaaagt
    26521 agcaaatcct acaaaaaatc tccctatctt ggaagagttc aaagactctg caaaaatcaa
    26581 agaattaaca aagcaataca atcagttatc atcagaatta caaaaagcaa tttctgaaat
    26641 caagtacacg ccaagagcaa gcaataaaaa tctgatccaa ttgaatatga atgacggcaa
    26701 tcaagttatt gtaaatatca ataatcttgc gaaccaaatg aaatattatt cgcaagtagc
    26761 caaagatatg gatgaaaaag gtgtgatcga catggaagtt ggtatcttct cgcatcctta
    26821 cggtagcact caagaaacgg aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga
    26881 aaatgcggat caaacaaacg aatcaagtga agaggcagaa acgcaaaaag cacaaacacc
    26941 tggatcgtct agcacaaacg gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat
    27001 agaagataat ccaagtacaa ctccgtcaag tttaaatgaa aattgataaa acaactttaa
    27061 aaagtaagaa tgtactttct aaaaaccagt aatttatggt agaattggaa gcagtgaata
    27121 tatctattaa taagtatatt ttaaaacgga cgctagttgt tcgcttgtat atggaatagt
    27181 aagtaggagg gaatcccatt catggcaaaa acaggaatgt atgtaggcct tgatattgga
    27241 acgacatctg ttaaagttgt cgtggctgaa tatatcgaca gccaaatgaa tattattgga
    27301 gtaggaaacg caaaatcaga agggattaac cgaggcatta tcgttgatat cgataaaacg
    27361 gtccaagcga tacaacgagc agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa
    27421 ggcgtaagtg tcggtttgcc agcaaacatg cttgaagtag aaaattgcca gggaatgatt
    27481 gcagttaacg gagattcaaa ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct
    27541 gcccttgttc gttcaatacc tcctgaacgt caaatcgtgt caatattgcc acaagatttt
    27601 actgtcgatg ggttcgaggg aatcaaagat cctcgtggaa tgatcggcgt aagattagaa
    27661 atgtacggtc tgttgtttac aggacctaaa acgatcatcc ataacatacg taaatgcgtg
    27721 gaaaatgccg gattaatcgt caacgaaatg gtgattactc ctttagcgct gactgaatca
    27781 attctttctg acggagaaaa agattttggt acgatcgtca ttgatatggg tggcggccaa
    27841 acaacaacgg ctgttatgca tgataagcaa ttgaagttta ccaatcttga ccaagaaggt
    27901 ggcgaatttg tcactaaaga tatctctatt gtattaaata cgtcatttaa caatgcagaa
    27961 gcgttgaaaa taaactacgg ggatgcatac ccagaacgga catcaccaga tgaagaattt
    28021 ccagtagatg tgattggtca gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa
    28081 attatttcag ctcgaatgga acagattttc aacaaagcaa aagatgcatt ggaccaaatc
    28141 gaagcattag agttgccagg tggcgtcgta ttgacaggcg gagctgctag tcttcctggt
    28201 gttgtggact tggcacaaga aatcttcggc gtaaatataa aattgtatgt tccaaatcac
    28261 atggggctga gaaacccggt atttacaaat gtaataagta tcgtggatta ttcagcaaac
    28321 ttgagtgaag tgtatcaatt ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt
    28381 caaatggtag ttgaacaaga aacaacaaac acatatgaga gctatgaagc acctgaagaa
    28441 acaatctacg atgagccgga accaaaagag tccggagaaa atgtaaaaaa taaaatcaag
    28501 ggtttcttta caaatatttt tgattaattc atcctgggag gaataagata tggaattctc
    28561 aattgataat aatatcaatg acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg
    28621 tggaaatgct gtaaaccgaa tgattgaaga aaacgttaaa ggtgttgaat tcattacagc
    28681 caacacagac gtgcaagcat taaaaaattc aaaagctgaa acagttatcc aattaggccc
    28741 caaatatact cgtggtttag gtgctggttc tcagccagaa gttggacaaa aagcggcaga
    28801 agaaagtgaa caatccttac gcgaagcttt agacggtgca gatatgattt tcatcactgc
    28861 aggaatgggt ggaggaaccg gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga
    28921 attgggcgca ttgactgttg gtgtcgtgac acgtccattc acttttgaag gaccgaaacg
    28981 tggccgtttt gctgcagaag gtatcgctcg tttgaaagaa aatgtggata cattattaat
    29041 tatctcaaat aaccgtttat tagaagttgt agataaaaag acaccgatgc ttgaagcttt
    29101 ccgtgaagca gataatgttt tacgacaagg tgtacaaggt atctctgatt tgatcacagc
    29161 gccaggttac gttaaccttg actttgctga cgtgaaaaca gtgatggaaa accaaggtac
    29221 agcattgatg gggatcggtg tggctagtgg agaagatcgc gtagtagaag caacgaaaaa
    29281 agcaatctcc tctccattgc ttgaaacatc tattgatgga gctgaacaag tacttcttaa
    29341 catcacaggc ggtttggata tgacattgtt cgaagcacaa gatgcttcag atatcgtagc
    29401 aaatgcagca actggcgatg taaatatcat tctaggtaca tctatcaatg aagaaatggg
    29461 cgatgaaatc cgtgtgacgg tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa
    29521 gtctagccga ccagctagac aagcacaaat gcaatcacct gctcaaaaga ctgtattaga
    29581 tatggatcaa gctaaaccaa cttcttcaga agaagaaaac agttttggcg attgggatat
    29641 cagacgtgaa caaaatgttc gtcctagagt tgatgattcc aattttgaca atatcgaaaa
    29701 aaaagaattt gatacattca accgcgaaga aacaaaatct catggcgatg atgaattaaa
    29761 tacgccaccg tttttccgtc gtaaaaaata aaggagagga agagcacatg attgctgaca
    29821 acttgcagaa aatcaagcaa gaaattcagg attcgtgtgc tcttgttcat cgtgatccga
    29881 aagaagttac attagtagct gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg
    29941 ttagagctgg cgttatgaat tgtgcagaaa accgagtaga taaattatta gaaaagaaac
    30001 aagatttatt tgattttcct gaaataaagt ggcatttaat tggtaattta cagcgcagaa
    30061 aggtaaaatt gattgtaaat gaaattgatt actttcatgc gttggacagt ttaagattag
    30121 cagaagaaat ccagaagcgg ttagagaaag aattatcctg ttttattgaa gtaaatgttt
    30181 ctggtgagga atcaaaacat ggaatttcac cagatgagct tttaccgttt gtggaatctt
    30241 tagctgcctg cacaaaaatc aaggttgttg ggttgatgac tatggcgcct aaagaagctt
    30301 ctgatgagca aatccataaa gtgtttggta cgctgaaaga attgcgtgat cttgttcaag
    30361 caaaaggtta tgcccatgca ccatgtagtg aattaagtat ggggatgagt caagactttc
    30421 aaattgcgat tgaagaaggt gcaacattta tccgtgtagg aacagcgcta ttcaaagacg
    30481 aataaaggag gaacaaaaat gccgctttta aacagaggag caattgctaa ttttttcgga
    30541 ttagctgatg aggaagagta cgaataccaa gattatcctg aaacaacaaa aaaggctgta
    30601 cagccaacta aaaaaaatac aacacagaat caatcaactc attctgtatc tgctgcgaat
    30661 actcatgaaa aacaaaaaac ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg
    30721 gctgaaaaga aaaaagtaat tgaactacat caatcaccta caaaaactgt agcgaaagaa
    30781 agaacagctt caagaacctc tacacaacct aaagcaaatc ttgctggaaa aatcactgta
    30841 atggaaccaa gagcttattc tgaagctatg gcgattgcta aacgaatcat tgctggagaa
    30901 gcaaccttag tgaattttca tttagtagaa gaaaaacaag cgagaagaat cgttgatttt
    30961 ctaacaggaa cagtttatgc actagatgga gatatcaaac gtgttggaga tgagattttt
    31021 ctttgtacac cgactgggat ggagattgac agttcaaccg ctcaatcttt tgcagatgcg
    31081 aatttgtttg atctgtaaga ggaggaacta cgatttatac tattgcacta ttacttcatt
    31141 tacttcaacg ggcagcctat ttctatagca ttatcttgat ggtatatgca ttgctctctt
    31201 ggtttccagg cgggtatcaa tcagggctag gacgattatt agctaagatc tgcgaaccgt
    31261 atatcagttt gttcgatcgt ctgcctttga ggattggacc cttggatttc acaattttag
    31321 gggcaatcct gatcttgaac ttagccgtac aaggtttagc acagatcgtt atatggataa
    31381 ctgtccattt agtttattga ttgaagcaac aaaatcttta ttctcagaat agataggagg
    31441 ggaaaatttt ggatgcaaat gtataccagc actttcgggc agatgaacgt acatttatcg
    31501 attcggtagg cgattggatt gaacaggttc aaggacaata tgcaccctat ctgaccgaat
    31561 ttcttgaccc aagacaatcc tatattttag aaacactgat tcgacaaagc agtgatttgc
    31621 gtttcatgtt ttatggcgga tatgaacagg cagaaagaaa aagatgtttg attttccccg
    31681 attattacga acctgtagag gaagattttg aaacagcatt gtatgaaatc cattatccta
    31741 gcaaatttgc cagcctaagt catgggaaaa tccttggaac tttagtggga acggggatca
    31801 aacgctctta ctttggcgat atcatctcgg acggtgatcg ctggcaagta tttattgcaa
    31861 atgaggtgga tcattttgtt gctgcacaag taacaaagat tggaaaggtt gctgtacgct
    31921 tggaaccaat caaatacaca gaaatgatta tgccgaaaga tagctggaca caagaaagag
    31981 gaacagttag ttccatgcga ctagacagtg tgatctctga gatttataat atttccagac
    32041 agcggtccaa gcagctgatc gaagctggta aagtaaaagt gaactggaca gaaaatacaa
    32101 gacctgattt tgtacttgaa ctattagata ttatttcagt cagaggttat ggcagagtcc
    32161 agatccaaga acttgagggg aagacgaaaa aagaaaagta cagggtactg ttcggtgtat
    32221 tacgtaaata aaataaaaag gtggtttact catggcttta actccattag atatccaaaa
    32281 taagacattc ccgacaaaaa tgcggggata taatcaagac gaagtagatg atttcttaga
    32341 tttagttgtt cgtgactatg aggaattgac tcaaagaaat cgagaattag aaaaagcagt
    32401 caaacattct gaagaaaaac ttgagtactt caatgaatta aaagatgctt tgaaccaatc
    32461 aatcatcgta gctcaagata cggctgataa agtaaaaaca agtgcaagca aggaatccga
    32521 agtgatcgtt acttctgcac aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg
    32581 tgcacatcaa ttaacaactg atgcagaaga aaaagcaaga aaaatcttga cagatgcaac
    32641 agaaaaagca agacagcttg cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt
    32701 ccatcaacgt atcagcttga tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg
    32761 ggatgaaatt ttacaaccat tctccagcta cgtgactgac agccatgaag tgatcaaaga
    32821 agttttagca aaacagcttg acaatgaaaa tgatactgat gtaaactcag acacaggagt
    32881 catagaagca cctatgacgg catttgatac acaggctatt gatatctcga tcgtgcctgg
    32941 tgaaaatgaa aacgagtaga acagaaaagc actttgttat tcttaaagcg agccgatgag
    33001 agtggaagtt cggtaagaca ctgcatggtg aaagatcctc tacttgagac ctgcttttcc
    33061 gaaattagag taagaagcag cggctgacct cgttattggt cacagagagt ttgcactaga
    33121 tagatgcaac taaatttggg tggtaccacg gcatgttcgt cccttgcggc tgaacatgct
    33181 tttttgtgtc cggaaaacaa ataaaggagt gtatggttga atgaaaatga aagaaacctt
    33241 gcaattagga aaaacaaaat tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg
    33301 gcaaaaagaa tgggaagaaa atcgaatcta ccaaaaaaga caagagttga acgaaggaaa
    33361 acctagcttt gttcttcatg atggacctcc atatgccaat ggtaatatcc atttaggaca
    33421 ttcattgaat aaaatcagta aagacattat cattcgttca aaatcaatgt ctggctatcg
    33481 tgcaccatat gttccaggat gggatacaca tggattgccg attgaacaag tattggctaa
    33541 taaaggcgtg aaacgtaaag aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata
    33601 tgcactttcc caagtagata agcaacgagc agatttcaaa cgcctaggag ttgcaggaga
    33661 ttgggaacat ccttatgtta cattagatcc ttcttatgaa gctgcacaag tacgcgtatt
    33721 tggtaaaatg gctgaaaaaa gctatattta caaaggattg aaaccaattt actggtctcc
    33781 gtcaagtgag tcttctttag cggaagctga aattgaatat aaagatgtaa aatctccatc
    33841 tatttttgta gctttcaatg tcaaagacgg caaagatatt cttgatgaag atacagcttt
    33901 tgtcatttgg acgacaacac catggacatt gccagcaaac caaggtattg ctgtaaatcc
    33961 aaaatttacg tatgtattgg tggaagccga tggccgtaag tttgtcgtag cgaaagattt
    34021 gctagaaaca gtccaatcag aaatcggttg ggaaaatgta acagttctaa aagaatttgc
    34081 tggacaagaa atggaatata tgactgcaag tcatccattc tatgaacgtg aatcacttgt
    34141 gattttaggc gatcatgtta ctttagacgc tggtactgga ttagtccata ctgctccagg
    34201 acatggggaa gatgactata tcgctggtag caaatataaa ctatctgtag tgtcacctgt
    34261 agactcaaaa ggattgttta cagaagaagc acctggattt gaaggtatct tttatgacaa
    34321 agcaaatcct atgatcactg atctattaaa agaaaaagga gctttgctga agctagattt
    34381 ctttactcat agttatcctc acgattggcg gacgaaaaag cctgtgatct atcgggcaac
    34441 tccacaatgg tttgcatcta tcgataaatt ccgtcagaat attttggatg aagtagaaaa
    34501 agtagagtgg gttatcccat ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg
    34561 cgattgggta atttcccgtc agcgtgcatg gggagtacca cttccgattt tctatgctga
    34621 aaatggagaa gcaatcatca caccagaaac aatcgaacat gtggcaaaat tatttgctga
    34681 acatggatca attatctggt ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac
    34741 ccacccaggt tctcctaatg gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt
    34801 tgattctggt tcttctcatg aagctgtttt acgtcagcga ccagaattat cattcccagc
    34861 agatatgtat ttagaaggat cagaccaata tcgtggctgg ttcaactcaa gtatcacgac
    34921 tagtgtggct atcaatggtg tagcaccata caaatcagtt atttctcaag gatttgcttt
    34981 agatggtgaa ggccgtaaga tgagtaaatc tttaggaaac atcattgcac cagaaaaagt
    35041 gatcaaacaa tttggtgcag atatccttcg cttatgggta tctagtgtag attatgaagc
    35101 agatgttcgt gtttctatgg atatcttaag tcaagtggca gaagtatatc gtaaaatcag
    35161 aaatacgatg cgtttcttat tagcgaatac agaagatttc gatcctaaaa aagatactgt
    35221 ttcgtacaat gatttacgtt ctgtagacaa atatatgacc gttcgattga accaagtaat
    35281 caaagaaatc cgagaagaag ggtacgacaa atataacttc atgcatattt accgtacagt
    35341 tatgaacttc ttgacggttg atctatcgtc attctacctg gattttgcta aagatgtagt
    35401 ttatattgaa gcagaagatg attatcaacg tcgttgcatg caaactgttt tctatcaaac
    35461 agctgtagct ttgacaaaat tattgactcc tatcattccg catacagcag aagaaatctg
    35521 gtcattcctg aaagaagaag aggagtacgt tcagttaagc gagtttcctg gttatgaaga
    35581 gtttgcaaac caagaagaat tgatggatac ctggactgct ttcatggact tccgtgataa
    35641 tgtcttaaaa gcattggaag aagcaagaaa cagcaaattg attggtaaat ctttggaagc
    35701 aaaactaact gtttatccaa aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga
    35761 tattgcacaa ttattgatcg tttcaccaga ctactttgaa gttatggcag cagatgaaca
    35821 agtgccagat aacgctatgg tatttgatga tgttgctatt acagtggaaa aagcagacgg
    35881 ggaaacttgc gatcgctgtc gccaagttcg taaagatgta ggagtagatg aaaaacttcc
    35941 tcatctatgc ggtcgttgtg caaaaatcgt tgaagacttc tatcctgaag ctgtagctga
    36001 aggattcgaa gaaaagtaaa agggaaaagg gggtgtgaca tgttctttgt cacaccccct
    36061 tttgttatca atcgtttaat tttccacgtt cacgatacca gttatctggt tgccagatcc
    36121 attcgaatcc gtctttttca agtagttcga aagctgcttt aggtcccatt gatccagctt
    36181 tgtagttggg aaaatccggt tgtgtttggt cccaagcttt tcgaatgaca tccacgatat
    36241 gccaagattg agcgacttct tcccaatgag agaagttcgt tccatcacca ttcaacgcat
    36301 ctaatagtaa tttttcgtaa gcttctgggc tattttcaac catttctgca ctatttctaa
    36361 attccaattt gattggttcc gtttcaaatc cttgccctac ttctttccca ttcaaggata
    36421 aagaaaatcc ttcagttggc tgaatataga tcgttagaac attaggtgga agtgtcgtat
    36481 cgtcacatgg ttcatcgaca gatgttttga atacattaac aggaacttgt ttgaatacga
    36541 tgttgatccg agtccctttt tcagtcaaac gtttgcctgt acgtacatag aaaggaacac
    36601 ctgaccaacg gaagttatcg atagtgaatt tgcctgcgac gaatgtttca gtctctgatt
    36661 gagcatccac tttgtcttct tcgcgatagc ccttgaattg tacaccatcc aattcacctt
    36721 gagcatattg cccgcgaacg aagttttcta acacttcttc ttcgttataa atgcggatag
    36781 ctttcaatgc tttgatcttt tctgtacgga tttctttttc ggaaaatgct actggcggtt
    36841 ccattgcaag taatgctaca acctgtaaaa tatgattttg caccatgtct ttaagtgcgc
    36901 cactatgatc gtagtagccc ccgcgatctt ctacaccgag gttttcgcca aaagtaattt
    36961 ggatattgtc gatatagcga ttgttccatt gagcctcaaa aatattattg gcaaaacgga
    37021 tagctgagat gttttggatc atttcttttc ctaaataatg atcaatcctg aaaatatctt
    37081 gttctgggaa tacttctctg atttgctggt tcaattcaaa agcagactgg taatcagaac
    37141 cgaacggttt ttctatgatc aaacgattga agccattttt tgtcataata ttttgtgatt
    37201 tcaaatgaga aacgatcgtt ccaaaaaatt gaggtgccat agccaaataa tagacacggt
    37261 taccgtttaa ttgatagtgt ccatctaatc ggtcagacaa ttcttttaat gtctgataat
    37321 gcgttgaatc atttacatca tgggattgat agtaaaaatg gcttgcaaag gtagttgctt
    37381 cttcatctga aggattcaat gcacggattg tttctttgac aacttcacgg tagtgctcat
    37441 cgctccaggg acggcgagcg gttccgatta cagcaaaatg ctcgcctaaa tttccttttc
    37501 tgtaaaggcg gaacaaagac gggtacaatt tacgctgggc taggtcacct gtaccgccga
    37561 atatcgtaaa caatacattt ttttcattag acatgtggat acactccttt atattttatc
    37621 gacaaaaatc gtgctggccg ccttaaagct gacggggatt ttctttctat cattttggat
    37681 agtgatcggt ccttcataag ctgcgatgtc aacgatctca tattcttcgt tgatattcag
    37741 gtcaatagtg actaagtaat ccaacaattc tttttcatca agcactcgtg cgatacgcac
    37801 ttttgtaccg acaggatagg actccaatgt ttgtcggcgt tcttcatgga caacttcctc
    37861 ttttttagga atcgatcctc catgaggaca atgttcagga tgattcaaat agttttctaa
    37921 atgatctgca agatgttccg aagtcacatg ttccaatact tcagcatcat catggacttc
    37981 attccagcta tagtctaaat gttcaactaa aaaaacttcc cataagcgat gtttgcgaat
    38041 cagactgcta gctttttgca gtccgcttgc agtcaattgt acaccttgat aaggggaatg
    38101 ttctacaagc tcttctttca caagtttaga aatcatttca ctgacagatg cagctgagac
    38161 atctagacta gatacgattt gtttattgtt gactttcgtt gtatctccac ctagttctaa
    38221 aatgattttc aaataatctt ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa
    38281 aaaccatcat tagtaagtgt aacaaaaaaa acgttaattg actatttttc taaataaaaa
    38341 acaaaggatt tttagacgtt tttacaacaa aaaacgaaag atgatagaga agactcattc
    38401 tttcgtttat aaaggatata tatatacatt gggagggatc tatttttcag ataacaactt
    38461 atatgaagtg tctgcagatt cgtcataaag agtttgttcg ggataagaaa agataagata
    38521 aaaaccatac tgatcacgta cgactaaacg atattcatct atttctacca cagatgtgcc
    38581 aagagactga ccgttgatca aaaacgtgta atcagatgta atctgtaatt gttgtttttg
    38641 ctggctatca ctaaagaacc atgtaccttg atactttgag agtccttctg acttttccgc
    38701 ttgttttttc tttttcaagt aaataaaact tgagagaacg gtaatgagtg aaccaagaaa
    38761 atagatcatt ttttttatca ccaaatcact cctttatgag aaaataatcg catagacata
    38821 ttctttcttc tttatttcat tgtaccgaat aaaagctaaa atttctctaa gactttcgac
    38881 tggttttttt actgtttttc tacaaattat gataggatac atagtaggaa gaaaggtgac
    38941 ataatttgaa gtatcagcaa gtggaaatag ctttttttat tgaccgcccg aatcggttta
    39001 tagcacattg tatgaaaaaa gacggagaaa taattattgc gcatgtcaaa aatacaggta
    39061 gaggaaaaga ggtcctgata ccaggcgctg aagtggctat tgtatttgct cctggaccta
    39121 aacggaaaac cgcctatgat ctgattgctg taaaaaagaa gggtgactgg tttaatatcg
    39181 atagtcaatt gcctaatcgg ctggcaattg atggtatttt agacggcacg atccttttac
    39241 caggattaac tggtccattt acggtataca agcgtgaagt aacttatctt cactccaaat
    39301 ttgatattta tttagagacg gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga
    39361 cacttgaaaa taaagcgatt ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac
    39421 atataggaga attaacgtat gccgcacaag atggttatgc cgcttatgtc ttgtttattg
    39481 ctcagttcga acatcttcat ctggcaacga tccatgaaga aatgcaacca gcactagctg
    39541 atatggttcg acatgcgcag caaagcggag ttcaaatcct cgcctataat tgtcaagtat
    39601 cggcagatga ggtaactgtc aagcaggcca ttccatttga tgtagatatc ccttttgaag
    39661 atcctataca atagaaagaa ggtaaaataa tgatcaactt aggtattatc ggaacaaatt
    39721 ggattactca tcaatttgtc caagcagctt taagcacaaa aaaatatgaa ttgacagcgg
    39781 tatattctag acatttggaa aaagcacagg aatttggttc tcattatgaa ggggatatcg
    39841 aattcgcaac agatttgaag acttttttca atattactca tatggacacc atttatattg
    39901 cttctccgaa tagtcttcac tttagtcaag ctaagcaagc aattttggca ggaaaaaatg
    39961 tgatagttga aaagccagct ttttcgacgc caaaagaaat ggatgaaatc atccatttgg
    40021 caaatgaaca caatgtgtat ttttttgaag cagcaagaaa tatccatgaa tcaggtttta
    40081 aaaagattgc cgattactta ccattaaaag acgagataat cggtgcaaat ttcagctata
    40141 tgaaatattc ttcgcgctat gaccaagtat tagatggaga agaaccgaat atcttctcga
    40201 ctcatttctc aggtggtgca ttgatggatt taggtgttta ccttgtatat gcagctgttg
    40261 cttggtttgg aatgccaaaa gaagtccatt atttcccaag aaagatttct actggtgtag
    40321 atggtcttgg atgggggatc ttacgttatg agaattttga tgtatcgatc cagccaggta
    40381 aaatcggtga ttcttattta ccgtcagaga tttattttga ctcaggaacg ctagtgatga
    40441 atggagtcaa tgcaattgaa caagcacaat ttcatgatcg cgcgcataaa gaaatcattg
    40501 atttggcggt aacagctgca gaaaatccaa tggcagatga agcagaggat tttgccaatg
    40561 tcatggctca tccgaaagat ccagcttggg gattgttgta tgaagagtgg atcgagctag
    40621 ctagaaatgt gaaccaagtg atttatgatt taagaaaaaa tggcggcatc aaattcgatg
    40681 cagataatga ggaagatttt taatgaacga atttgtacaa gtatttcccg aaaattggca
    40741 gaaaaaatat gaggataaag ggtttatctc accttctctt attcaacgag cagtttttca
    40801 gccactaagt aataaacaaa gtatagtagc ggtttctcct acaggttcag gtaaaacact
    40861 ggcttatctt tggcctctac tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat
    40921 ttttgcttct tctcaagaac tagctattca agtagcagat gttgcacgtg aatggggaaa
    40981 agacaaagag ttgaaagtcc aatctttggt gggcggagcc aacgtcaaac gtcagattga
    41041 gggtttgaag gaaaaaccag aaatcttgat tggtacacca ggaagaatat tggaattgat
    41101 gaaagcaaaa aaaataaaag cacatcaagt gaaaacaatg gtatttgatg aagcagacca
    41161 gctatttgac gctgggaaca gccaaatcat tgatcaaatt cttcatcaag ctccaacaga
    41221 gtatcagcta gctttttttt cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat
    41281 cactgggaaa acgtttgaga caattgacgt gacagcagag gacgattctc gaaaaggact
    41341 gagacattac tttttacgtg taccgatacg aaagaaagat gactacttga gacgtctcac
    41401 gcatatagaa gattttcatg gtctgatttt ctttaatcaa ctgactgaat taggcgtaat
    41461 ggaagaaaaa ttgctgtata gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa
    41521 gctactccga aaagcagcgc tagaacaatt caaaaagaaa atggtcagag cacttttgac
    41581 cacagatgtg gcggctagag gtttagatat tacaggtctt ccttatgtag tgaatgcaga
    41641 agttccgtta agtgaagaag cttatttgca tcgttcggga agaactggtc gaatgggtaa
    41701 tgaaggaata gtaattacac tcgtacaaga taataatcta agagatttaa aacggctttt
    41761 acgtccatca aatataacac ttgaagagat ttttttatac ggaggtaagc tgcaaactga
    41821 gcagccaacc aaagaagatg cagctcctgc agtaaataaa aagtatgcga aaactttttc
    41881 tggaaaggag cagaacccag aatataacaa agaaaaaata agaaaaaaag ttaaaaataa
    41941 atcaaaaaaa gagagaaata aaggagcaag gcgcaaataa gcgccttttt atgctatgat
    42001 tatgaaaacg ggaacaaaat tggttgccag aggaggggtt atgtgaaaga acgtcaagaa
    42061 gagatcttgc agctattgac agaaaaccaa caaggattga cagcaagtga tgtagctgag
    42121 cgcttaacta tcgatcgaag caatgcaagc cgatatttaa gtgaactata caaggcccat
    42181 catattgtaa aaaccgctgg ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa
    42241 tctgatgaag tgcatgtcga ctcttctacg caagtgactt ttgaaacact cgttggagaa
    42301 aatgattctt taaaagtcag catacagcag gcaaaagctg cgattcttta tccaccgcgg
    42361 gggttgcata cgattatttt tggagaaact ggtacaggga agtcgatgtt tgctgaatgt
    42421 atgtatcatt ttgcaatcga ttcagagatg ctttctgcag atgcgccatt tgtttctttc
    42481 aattgtgcgg attatgctca aaatccgcaa ctgctctttg gacacatctt tgggatcaaa
    42541 aaaggggctt acacaggagc atctcaagat agtcccggtc taatagccaa agcagacggc
    42601 ggtatattgt ttttagatga gatccaccgt ttaccgccgg aagggcagga aatgctgttt
    42661 actttcattg ataaaggtat ttaccgtccg cttggagaaa gtgcacaagt acatgaagca
    42721 tctgttcaga tcattggggc gacgactgaa tcttcagaaa gtttcttatc tacgttcaat
    42781 cgacggattc ctatggcaat caccttgccg aatcttgctt cacgttcact ggatgagcgt
    42841 tatgaaatca tctctctttt tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat
    42901 atcgaaaaag aagcgattct tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa
    42961 gtgaaacgag acttgaaact agtctgtgca aaatcttttt tacattaccg tactcatcat
    43021 gagaaaaagc taatcattcg aaaagaagaa ctttcccttc aagtacaaaa aggattactg
    43081 aaaatcaagg aaataccgga acgtctcgac cgattcatgg acagcaaaag tcagtatttg
    43141 acatttgaac caggatttgc tgatgttgtc tggtcacaag atccagaacg aaacatgcag
    43201 gtctataacg atattgagga aaaagtcact tctctttccg aaaccggtgt ggagaacatt
    43261 gatctagaga ccctcatttc aaaagatgtg gatgcttatt tccagacata tgtcaaagaa
    43321 ttgactaaaa gttcgattcc caaagatctt ttgccagatg aaatctggcg gttaaccaat
    43381 caattgtatg atgtggctga aaaacggtta gaccgtattt ataatgaaaa agctcgtttt
    43441 gcttttgctt tgcatctgca aagtacattg gatcgtgtga gagaaggtca tatgatcgtc
    43501 cacccagatt tgaataacgt acggaaaaat tttaagaggg aattccaggt agcaatcgat
    43561 ctttcaacga tcattgaaga agaagaacaa gttgagattc cttttgatga aatcggcttt
    43621 attagtatgt ttctttctat caatctagga gaaagtgagc ctgttaaaga aaacaaagta
    43681 gatgttctca tattgatgca cggcagacag actgcttcaa gcatgttgga gatggcacaa
    43741 gaactattag gaacaaaagt agggaaagct tttaatatgc cactggttat ggaagttcaa
    43801 acaatgtatg aagaagtgtt acaatatgtc aaaaactatc aagagcattt gacgaatggc
    43861 ctactcttgt taacagatat gggatcatta aacaccttca gtgatttgat ttatgaagag
    43921 actggcattc ggacgaaagc tatcacgatg acaagtacca tgattgtgat agaagcgata
    43981 cggatggcaa gtgttggaag aagcttagaa gatatttatc aaaatatcca gctttccttt
    44041 gaatcgatcg tacgtgatca gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa
    44101 gccgtaatcg tgacatgctt tactggtgaa ggagtagctg ccaaattata tcagcgtatt
    44161 atgccagtga ttaatcaaaa taaggtagaa ctgatccaga tgcagttttt agaacgtgaa
    44221 tcattcaaaa aacacatcga tgccttattg gaagaatatg agatcaaagc aattgcggga
    44281 acagttgatg ttgattatca aaatatccca tttttttcag cctatgacgt ttttgatgat
    44341 gaaaaactaa atattttaaa gcgtatagct gatgatgaga tcccgacagc taaaattgtc
    44401 gattcacttg ctggatcatt aagcgatgtc ttttctattg atgaactgat ccgttcattg
    44461 caaaagacag ttcagcagat ccagaccgat ttgtcgatta tcgtggaacc tggagtagat
    44521 actggaatcg ttatccattt agccttcatg ttagacggat tgatcaaaca agaaagccat
    44581 cggcaatttg agaaactgtc tattttctca aaaatttatc gtttggaaat ggatatcgtt
    44641 cgggcaaact tgatggcact agaacgaaaa tatcaggtaa aaattccaga agatgatatc
    44701 gcatttctta cacaaatgtt tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac
    44761 tgtttacaca ctaaacatct gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg
    44821 ctatttcagc tctttttttt attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat
    44881 aaaaggagtg ttaaaaatgg caaaaaaaac aatcatgtta gtttgttcag cagggatgag
    44941 tacgagttta ttggtcacaa aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga
    45001 tatttttgcg gtctctgcct cagatgcaga taataattta gaatctaaga atgtcgatgt
    45061 attattatta ggtcctcaag tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc
    45121 taaaggtatt ccattagatg tcatcaatat gcaagactat ggcatgatga acggagaaaa
    45181 agttcttgca caagcagaaa atctaatgaa ataaatcaag tatgcagttg ggggtataac
    45241 aacgtggaag atcaacaaaa tctagaagcc atcatggggt taatcatgtt tggcggtaat
    45301 gcaaagagcg atgcaatgga agcgattgcg gctgctaaaa tcggtgattt tgagttagcg
    45361 gataggaaaa tcgctgatgc agaagaatca cttatacaag cgcatcatgc acaaacagac
    45421 atgttgacac aagaagcaca aggaaatcat atgcaagtga cattattgac tgttcacagt
    45481 caagatcact taatgacatc tattgcgttt actgatttag caaaagaaat catcgaactt
    45541 tatcgtcgcg tatacagcga ataaatacaa cttctttttt gaacggaaga agaaaaattt
    45601 ttgaacggat tttttatttt gttataagga gaactctctt tatataaaaa acttatagga
    45661 ggaagtaaaa aatgaacgga ctatcaagtt ggatggagaa atacatcctg ccggttgccg
    45721 caaaaatcgg agcgcaaaaa catttagttg ctttgcgtga tgcttttatc ggcatactgc
    45781 ccgcaacaat ggcgggatca gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc
    45841 aacagtttaa cagtacctat gctgacagtt tagcagcaga caaaggaatc tttgccgtat
    45901 tgaatgtcat catcggaatc aatggttttg tctggaacgg tacactagca atcgccggat
    45961 tgatctttgc cttttcttgg gggtataatc ttgcccgagc ttatggagta aatgatctag
    46021 ctggggggat cgttggttta gctaccttga ttcaaggtat ttcctttggt ccagcattat
    46081 cagcagcatt agatgtgaat gttccttcaa atgtcgcaga tgcaatcaat agttctgaga
    46141 ttggtgcaac gattgcagat ggcacactgt cagttggatt atggggttgg ctaaaactag
    46201 atcatttgaa tggaaacgct tattttacag ttatgatcat gggagctatt tcagtcatta
    46261 ttttttgtaa attgatgctt gccaacatta cgatcaaaat gcctgattca gtaccaccag
    46321 cagtatctaa agcatttgca gccattttac cagcgacgat cgctttatac gtcattgcta
    46381 ttatcaatta tatcgtaggt cgtgtagctg atgggcaact gatcattgat ttggtgcaaa
    46441 aatatattgc agaaccattc ctaggattat ctcaagggtt gggagcagta ttgatcgtca
    46501 cagtatttgt tcaagtattc tggttctttg gtattcatgg atcaaatgta ttggcaccag
    46561 tgctagaggg aatctgggga caagcacaac taatcaatat tgatattttc caaaaaggtt
    46621 ataacggaaa aactggtaca ccagccgtgt tagatgcaat cgaagatgga aaagcttata
    46681 tgtgggtccg cggatcgttc gatgcttttg catggtttgg cggatcaggc ggaacgatcg
    46741 tcttactgat agctatcttg attttctcta aacgtgcaga ttatctaaca gtagctaaat
    46801 tatccattgg gcctggtatc ttcaatatca acgaaccagt gatgtttggt ctgccaatcg
    46861 tattgaatgc aatcatgttt atcccattct tgattgctcc agtagtagca acagcaattg
    46921 gatggacagc tacttatctt ggcctagtcg ctccggtatc gcagcaagtc acatgggtag
    46981 taccgccgtt cttattgtca ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa
    47041 cattagtatg tatggtcgtg actttcttga tttgggcacc atttgtcatc tctgcaaaca
    47101 aaatggaccc tgccgcaggc gaacaacaat aagatgaacg tgaggagcgg gacgctttaa
    47161 gtttcgttcc tcataatgaa ttttcgagga ggaactgaaa tgattacaat tgccagtgca
    47221 atgcaacaag atgaaatcaa agaattgtta gaaggataca atgaagaagg aatgactttt
    47281 acatttaaag aaaaacaagg aatcaagctg ttctttgaaa caagtgcaga agatccggaa
    47341 gttgcggcta aaaaagcaaa ggaactaatc aaagcacagc cttggggaac agtcctttat
    47401 tttcaatcaa cagctgttta gaaaatggtt taaaaagata ggatggttga gatgataaaa
    47461 aacggtttat ttttatgtag tattggttct ttgatcgtgt tgtatagttt gaatccacat
    47521 tcgcaaaggt atgatttgta tagtatggtc acaggtcttt ttctaacagg attaggaatc
    47581 tatttcttca tgaaggggaa aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa
    47641 tcacgaaaaa attaaatatt ccagcatcgt ttttttacga taaagttatg gactctgtcc
    47701 ttttcgatgt acgtaaagcg accggcaaat cagtaactag aaaacagctg aaaaatttgg
    47761 agtacgtcaa acaattctcg caaaataacc gggctcgcat aaaaatcgaa gaagtcattg
    47821 aaaaccagtc ttataagttt cgtacatcga caacgaagaa tgaattcgtc gttcattatc
    47881 aaatcaaacc attggacgat tcgacctgtg aggttcatta cacagaaaaa atggagtctt
    47941 atggcatgct tcaaaagttg aatgatatgc ttttaggaac aatcttgatg tattttaaac
    48001 ggagacgttt caaaaaaatg ctagatatga tcgaagcaac gtattaaatc aatgaaacat
    48061 ggtactattt agttattgaa aaatgaagta agctagaagg aatttttcat aggaagatag
    48121 atctttcctg cgaatcctca ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa
    48181 agtaagagag ctaggtgtat cttcgattga ggaaatgttt gatttagcca cttatgcatt
    48241 taatggggca gatacacctg aaaggcgaga acgttttcgt acacttgcgg agaattcttg
    48301 gaattacgga ttttttgatg aggaggatcg gctaacaagt caagtaatgg cgaccccttt
    48361 tccagtgaat ttttacggac aagagtacct aatggccggc attggctatg ttgcttctta
    48421 tccagaagca aggggacaag gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg
    48481 ccgtgatcgt aaagtaagct tatcttatct ggcgccattc tcctatccct tctatcggcg
    48541 ctatggctat gaacaatcat ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc
    48601 gtttatcaaa aaaaaatctg gaaaaataaa gcgtatggat tttgaagatg caaaagctgc
    48661 aatcagaaga atttatgaac agatgccgga aaaccaacga gctggtctga agcgcgaaga
    48721 ctggtggtat acgtataaat tcaagcaaaa aggcaattac cagtttgctt tgcattttga
    48781 tgataatgag gaagcaacgg gatatatcgt ttatcagctt gcaacgtctt cctttattat
    48841 tgcggagtgg ggatttttgg atcatgatgc tttttgcagc cttgttcgct tcgtaagttc
    48901 tcacaatggt gcttttgaaa catttgaata ttcatgcggc tacggcggta atgatcaaaa
    48961 ttatctatta gaaaatccat ttgcttctgt aatgatcaca ccttatatga tggcgaggat
    49021 cgtagatatt tctttgtttt tggaaaatta tccatttaaa aagagacaag ctgcatttgc
    49081 cctacaaata gaagaagatc attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat
    49141 cgaaaatgga aaaaatcatc tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg
    49201 aagtatccaa catatcacgc agctattatt agggtatcgt aaagtggaag agttggtatt
    49261 ccaagaaaga atacaggtga caaaagaata tgaagaaacg ttaagctcaa tcttgccaca
    49321 gcaacagcca attcttaatg actatttttg ataaaaaacg ggtgatgaca atatttttgt
    49381 caccaccctt ttgtttttca tttggcattt gaaggaaaat gttaaagtaa atcctctttt
    49441 ttcgtaaatt tgaatttttt gttttctttt gttttagggt tttctttttt gtggtcttgg
    49501 attgcttctt tcgtaatctt ttcccgattt tttttagatg aatctaagcg ttctgcgtat
    49561 actttttctt ttggcttatc attcattgga aaggacctcc ctacattatt tcattctacc
    49621 tctagtttat catctgttaa ggactagtgg aaacgttttg cctaacttat aagctgattt
    49681 ttttagcaga taagcttgca agtaaaaaac aaacaagcta caattgattt attgaaattg
    49741 ttcctgtagc tcagtaggat agagcaatcg cctcctaagc gataggtcgc tggttcaatt
    49801 ccagtcagga acgtataaat aacccctgta tcctttgcgg tacaggggtt tgttttgtat
    49861 ttgtgccaaa aatgtgccaa actagttatc atttttatat aaactatcga acacagtatt
    49921 gattttttct ttatcctgat cttcaagctc tcgaacaata tgaagataag tagacattgt
    49981 agtttctaaa ctgctatgtc ctaaacgttt cgatacgcta agtatattta ctccttgata
    50041 aagtaaaata gatgcatgtg tatgccttag tccatgcaaa gtaaattgct tttcaatccc
    50101 taattctttt aattttttgc gcaaatattt gctgacggcg tttgatgaaa ctaatccatt
    50161 ttttaagttg aaaaaaacaa aattatgagg gtttttgatt tcaaaattct cgaataattc
    50221 tttttgattg attttaaact tttttaagag atcaatcgta tgtttatcaa tggaaatttt
    50281 cctatttgaa gtttcgtttt ttgtttttcc ccattcattt aatttataat tccatgtttt
    50341 attaatagtg atgatttgat cttcgaaatc gatatcttcc catgttaatc ctagaagttc
    50401 agcaaatcgc attccagtgg caccagcaac taacacgagc ataggagaag agtactgcgc
    50461 agaaaggttt tcttctacga gtttcattaa agatttaaat tgatcataat ctaaatattt
    50521 atcttctttt ggcttcaatg aatcttttcc tttgattact gcttttctag ttggatcaaa
    50581 cggaattaat ccttcttcta cggcatcttt caacgacgct ctaatatggt tattaaactt
    50641 aataacggta gattttacat ggtctttagc atacttattt aaaaagcgtt gatatcccac
    50701 tctatctaaa tcagaaatca ataccgctgg catatatttc tttatgttca ttaacgtatc
    50761 ttcgtatttt ctataagtga taggagatac tgttccttct ttataaagtt gcatccaatc
    50821 ctcaaagtaa tctgataata atagattttt gcgatcccct ttaaggcctt tgttcaagtt
    50881 atattctaat tcgttggcgg catcttttgc ttctcctttt gtcttaaatc ctgattttct
    50941 tatcttcgtg tattttccgt catctttttt gtatgaaatt tcgtattgcc aactatttcc
    51001 acgtttgact aatcttgcca taattgaatc agctctcttt ctctgataca ataggaacta
    51061 taaagaagcc cattgtttgg gttttattat tttttgcaca tcctttttgc ttgccggcgc
    51121 aaggatgtgc tatttgtcgt tttaatggta taattggatg tgtattagat catccaatca
    51181 gaggtgttta ttatgattaa agtgattttt aaaagaataa ctgaacttcc agagtttaga
    51241 ttatttgttg attattggta tgtctggttt tttattgttg cattgctgat aggtctagat
    51301 gtcatattag aaagaaaact taagtaagag ttgagttaat aaattgaatt cctaaatgag
    51361 atattttgta gcccatattt tgtttgccga catcacctaa tactatggag ctaatcgttt
    51421 tttctaacag accaaaatca gataatctat ttaagctacc atctattagc tcttgtgaat
    51481 agccagacat gctgatattt ccagtgaaat tttcgtttcc acgactcatt aagcatgcta
    51541 acaattgaat ctcaatcgat gttaattgat tcagtacaag aagataatac tcctcgttat
    51601 cccatgaagc gttgttaatt cgaagtaaac aattcttata aagattttta tacatatcta
    51661 ttttattttg tgcctttgat ttttctacct cgtcatttat cccttcgaat attccaatga
    51721 gttggtcctt gttctctaag ttgaaaacat cttctggaat ttgatcgcga atgttttcta
    51781 atgattcgtt taaatttttg tagaatttct cgatgcgttt gaaacgcttc tcgtttttag
    51841 acccaaaata aagtgactgc acaacgccac caatataagg aattgctcca ataccgcctt
    51901 caactattaa ttcaagatat tcttttttgg ttagtttttc attgctatta tccatagtta
    51961 cctcctattt tgttatttcc tttacaagca ttgtgactcc tgatggcact cttttgtata
    52021 ggttttatta ttgtgcacaa tctaactctt agtggggcgt ggttcattta ttttttactt
    52081 actttactat taatcatatc ccattgagca taggattttt ctatgttcga tcctcttgaa
    52141 ctaatttctc ctgtaaaagt tactttatcg ccctttgtaa aggtatcagc attgtttaag
    52201 tccttcgcaa aaattacata tgaaacttta ggtgttgcag aaatatcatt ccaactttta
    52261 tcatcgtact ctttgtctgc tataatggct attctagtag tcattgattc gataacagtt
    52321 ccttcaaaag tatatgtttt accactaata tatttagtaa aagctgtatt ttgctcagta
    52381 gctggagtaa tagaataata actatctaag aaagcacccc agtcatgatt atttgtctct
    52441 aaaaattctt caaattgagt taggctttta ttgctgctgt tagatgtagt agtttgagta
    52501 tcagatgatg agctttcctg tttgttattg tcatttgcct cgtttgatga ggaaagcgag
    52561 aaacctacgg tagtaaaaat aatcccgata ataaggagaa tcataggtgt tttcttattt
    52621 gtttttttga taaatcttac aattaacatg attaaaccta taataaataa aacaatacca
    52681 gtaaaaccaa atataccgtc cattaataga tcctctttct cttttgatat tgaatattat
    52741 aaaccaagca attctttttt cttaaaatcg aattcttctt gattaataat cccttcatct
    52801 aacaactctt tatacttttt aatttcatct gcacttgaaa tttgtgtttc tttggaatta
    52861 ttatctaata tagattgttg cttctctata tattttttta aattttccat ttcattccaa
    52921 tatttttttg taaacataac ggtgttttca tctttcgtgg ccgctaatat acctccgcga
    52981 ctttcgtttc cgcctagcaa ggtaaattgt atataaccat tactcatacc tggttttttt
    53041 aattgtacgg ctgatatatt tttaaagggg atagtttttt ctcctttaat accttgatta
    53101 actaaattta taaatccttt tctaataatt gaaatagaat catcagttac tttaatcaag
    53161 gtttttcctg gagattttat taaaatctct ttttccattt tttcttcctc atttctgtga
    53221 tatg
//
LOCUS       DAFEML010000014        51675 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFEML010000014
VERSION     DAFEML010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.014"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(82..2444)
                     /locus_tag="LP468_000943"
                     /pseudo
     CDS             complement(82..2444)
                     /locus_tag="LP468_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            2892..3065
                     /locus_tag="LP468_000944"
     CDS             2892..3065
                     /locus_tag="LP468_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080497.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(3222..3569)
                     /gene="rbfA"
                     /locus_tag="LP468_000945"
     CDS             complement(3222..3569)
                     /gene="rbfA"
                     /locus_tag="LP468_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL2080498.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3596..5902)
                     /gene="infB"
                     /locus_tag="LP468_000946"
     CDS             complement(3596..5902)
                     /gene="infB"
                     /locus_tag="LP468_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL2080499.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5915..6226)
                     /locus_tag="LP468_000947"
     CDS             complement(5915..6226)
                     /locus_tag="LP468_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL2080500.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6223..6516)
                     /locus_tag="LP468_000948"
     CDS             complement(6223..6516)
                     /locus_tag="LP468_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL2080501.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6538..7713)
                     /gene="nusA"
                     /locus_tag="LP468_000949"
     CDS             complement(6538..7713)
                     /gene="nusA"
                     /locus_tag="LP468_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL2080502.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7736..8209)
                     /gene="rimP"
                     /locus_tag="LP468_000950"
     CDS             complement(7736..8209)
                     /gene="rimP"
                     /locus_tag="LP468_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL2080503.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8354..12712)
                     /locus_tag="LP468_000951"
     CDS             complement(8354..12712)
                     /locus_tag="LP468_000951"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL2080504.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(12924..14633)
                     /locus_tag="LP468_000952"
     CDS             complement(12924..14633)
                     /locus_tag="LP468_000952"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL2080505.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(14701..15969)
                     /gene="rseP"
                     /locus_tag="LP468_000953"
     CDS             complement(14701..15969)
                     /gene="rseP"
                     /locus_tag="LP468_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL2080506.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16130..16930)
                     /locus_tag="LP468_000954"
     CDS             complement(16130..16930)
                     /locus_tag="LP468_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL2080507.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16927..17739)
                     /locus_tag="LP468_000955"
     CDS             complement(16927..17739)
                     /locus_tag="LP468_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL2080508.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17934..18491)
                     /gene="frr"
                     /locus_tag="LP468_000956"
     CDS             complement(17934..18491)
                     /gene="frr"
                     /locus_tag="LP468_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL2080509.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18494..19216)
                     /locus_tag="LP468_000957"
     CDS             complement(18494..19216)
                     /locus_tag="LP468_000957"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL2080510.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19352..20233)
                     /locus_tag="LP468_000958"
     CDS             complement(19352..20233)
                     /locus_tag="LP468_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL2080511.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFKDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20332..21114)
                     /gene="rpsB"
                     /locus_tag="LP468_000959"
     CDS             complement(20332..21114)
                     /gene="rpsB"
                     /locus_tag="LP468_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL2080512.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21473..21952
                     /locus_tag="LP468_000960"
     CDS             21473..21952
                     /locus_tag="LP468_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL2080513.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22169..23260
                     /gene="phnW"
                     /locus_tag="LP468_000961"
     CDS             22169..23260
                     /gene="phnW"
                     /locus_tag="LP468_000961"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL2080514.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23253..23381
                     /locus_tag="LP468_000962"
     CDS             23253..23381
                     /locus_tag="LP468_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL2080515.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            23385..23930
                     /locus_tag="LP468_000963"
     CDS             23385..23930
                     /locus_tag="LP468_000963"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL2080516.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(24384..26075)
                     /locus_tag="LP468_000964"
     CDS             complement(24384..26075)
                     /locus_tag="LP468_000964"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL2080517.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26495..27442)
                     /gene="arcC"
                     /locus_tag="LP468_000965"
     CDS             complement(26495..27442)
                     /gene="arcC"
                     /locus_tag="LP468_000965"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL2080518.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27557..28576)
                     /gene="argF"
                     /locus_tag="LP468_000966"
     CDS             complement(27557..28576)
                     /gene="argF"
                     /locus_tag="LP468_000966"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL2080519.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28667..29896)
                     /gene="arcA"
                     /locus_tag="LP468_000967"
     CDS             complement(28667..29896)
                     /gene="arcA"
                     /locus_tag="LP468_000967"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL2080520.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30357..31058
                     /locus_tag="LP468_000968"
     CDS             30357..31058
                     /locus_tag="LP468_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2080521.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31667..32683)
                     /gene="tsaD"
                     /locus_tag="LP468_000969"
     CDS             complement(31667..32683)
                     /gene="tsaD"
                     /locus_tag="LP468_000969"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL2080522.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32680..33144)
                     /gene="rimI"
                     /locus_tag="LP468_000970"
     CDS             complement(32680..33144)
                     /gene="rimI"
                     /locus_tag="LP468_000970"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2080523.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33151..33693)
                     /gene="rimI"
                     /locus_tag="LP468_000971"
     CDS             complement(33151..33693)
                     /gene="rimI"
                     /locus_tag="LP468_000971"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2080524.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33677..34399)
                     /gene="tsaB"
                     /locus_tag="LP468_000972"
     CDS             complement(33677..34399)
                     /gene="tsaB"
                     /locus_tag="LP468_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL2080525.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34590..35570)
                     /locus_tag="LP468_000973"
     CDS             complement(34590..35570)
                     /locus_tag="LP468_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080526.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35594..37078)
                     /gene="galT"
                     /locus_tag="LP468_000974"
     CDS             complement(35594..37078)
                     /gene="galT"
                     /locus_tag="LP468_000974"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL2080527.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAAKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37090..38079)
                     /gene="galE"
                     /locus_tag="LP468_000975"
     CDS             complement(37090..38079)
                     /gene="galE"
                     /locus_tag="LP468_000975"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL2080528.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38327..38494
                     /locus_tag="LP468_000976"
     CDS             38327..38494
                     /locus_tag="LP468_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL2080529.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38556..40367)
                     /locus_tag="LP468_000977"
     CDS             complement(38556..40367)
                     /locus_tag="LP468_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL2080530.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40364..40729)
                     /locus_tag="LP468_000978"
     CDS             complement(40364..40729)
                     /locus_tag="LP468_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL2080531.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40892..41287)
                     /locus_tag="LP468_000979"
     CDS             complement(40892..41287)
                     /locus_tag="LP468_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2080532.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41305..42267)
                     /locus_tag="LP468_000980"
     CDS             complement(41305..42267)
                     /locus_tag="LP468_000980"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL2080533.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42267..42479)
                     /locus_tag="LP468_000981"
     CDS             complement(42267..42479)
                     /locus_tag="LP468_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL2080534.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42500..43198)
                     /locus_tag="LP468_000982"
     CDS             complement(42500..43198)
                     /locus_tag="LP468_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL2080535.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43218..43760)
                     /locus_tag="LP468_000983"
     CDS             complement(43218..43760)
                     /locus_tag="LP468_000983"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL2080536.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43892..44896)
                     /locus_tag="LP468_000984"
     CDS             complement(43892..44896)
                     /locus_tag="LP468_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL2080537.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44893..45882)
                     /locus_tag="LP468_000985"
     CDS             complement(44893..45882)
                     /locus_tag="LP468_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL2080538.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45879..46685)
                     /locus_tag="LP468_000986"
     CDS             complement(45879..46685)
                     /locus_tag="LP468_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080539.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46851..47807
                     /locus_tag="LP468_000987"
     CDS             46851..47807
                     /locus_tag="LP468_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080540.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATAANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47884..48402)
                     /locus_tag="LP468_000988"
     CDS             complement(47884..48402)
                     /locus_tag="LP468_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2080541.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48490..48639)
                     /gene="rpmG"
                     /locus_tag="LP468_000989"
     CDS             complement(48490..48639)
                     /gene="rpmG"
                     /locus_tag="LP468_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2080542.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48867..49313
                     /locus_tag="LP468_000990"
     CDS             48867..49313
                     /locus_tag="LP468_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL2080543.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49508..51403)
                     /gene="asnB"
                     /locus_tag="LP468_000991"
     CDS             complement(49508..51403)
                     /gene="asnB"
                     /locus_tag="LP468_000991"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL2080544.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        14525 a        11013 c         9075 g        17062 t
ORIGIN      
        1 ttttttccgt tttttttatt tattttttca gtttcttaat caatgtaaaa aattctattt
       61 tgcgggatcg attttatcat tttattggtc aagatttttc catttccaat ccaatacttc
      121 tggcagatca ataccatttt cacgaatata gttttgatgt tcttgtaatt tctgatccat
      181 ttttttcgca aaatcttctg cttgacttcc tttgattttt aaagctgcgt cttttgccaa
      241 atgataacga tcaagttcat ttactacacg catgtcaaat ggtgtcgtga tatctccatt
      301 ttctttgtag ccatgaatca ttaaatgatg gttatgacga tcaaagaaaa tcgtgcggac
      361 caatgtttca taaccgtgga aagcaaataa gatcggtttg tcttttgtaa aatattgatc
      421 aaattcttca tcgctcaacc cacgcggatc ttgacttgga tgacgtaatt tcaataaatc
      481 tacgacattg atgaaccgaa tttttagttt tgggaattct tccagcagca aagttacagc
      541 tgctaatgct tctaagttag attccgttcc tgcagcagca atgaccaatt caggttcctc
      601 ctcttttgct gtcgaagccc aatcaatgat tttcaagcct tcattcacta agacggctgc
      661 ttcttctgct gagtaaaatt gagcacgcgg atgtttggaa gagatgatca aattgatttt
      721 ttctgacgag cggaatgctt tatccatgac tgcgagcaat gtatttgcat ccgcaggcag
      781 atattcacgg atgaactccg ccttcttttc tgccaaatgt gtcaatattc ctggatcttg
      841 gtggctatat ccattgtgat cttgctggaa gactgttgag cttgcaatga gatttagcga
      901 aggataatca tttcgccaag aaaggtcatg tgatttccgc atccatttga agtgctgagt
      961 caacatagag tcaaccactc gcaagaatga ttcgtaactt gcaaaaaacc atgccgtcca
     1021 gtcagaacgt acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg
     1081 acgcgaccag atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg
     1141 cgatttgtcg ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat
     1201 atacggaaat tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc
     1261 atatcttctg ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct
     1321 ggcataataa gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt
     1381 tggtcaccag taggcgcgat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat
     1441 aatttttctg gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt
     1501 tcttgatcta caggaatcgg tacttggtgt gctcgaaagg ttccttcaat tggttccccg
     1561 tcccattctt ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt
     1621 ggcatcacga catctgttgc tgtcttcagg cgagcttctt tttggatgga tttaattttc
     1681 tcgattgctt gatccatttt ttcagccata acaggattta atttttctga atcatttcct
     1741 tcaataaaga aaggttccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat
     1801 ttacgtgcca agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa
     1861 acagctccat ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga
     1921 ccggtttctg cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat
     1981 acagctccga ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct
     2041 ggtgtttctg gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg tttgaataat
     2101 ttttgcattc ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct
     2161 aaataagcat tcgataccat gacttgtccg ccgtgtcctg gcccttcaat ataaaacatg
     2221 ttcaaatcat atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga
     2281 atcgttcccc aatgaccgat tggatgtttt ttgacatctt cgggtttcag tgtacgtctc
     2341 agtaaggggt tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac
     2401 caagccgtca ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt
     2461 cattattact cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt
     2521 catttgtttg gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc
     2581 ctttcgctga cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc
     2641 gcagttcatt tcgctcctca tcatgcataa tttgctgaat gacgctgggc cagttaacac
     2701 attgctggaa aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta
     2761 aaagtctctg ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct
     2821 acagggatta tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca
     2881 ataacttcaa cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg
     2941 gtgcaggttc cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt
     3001 acaatctagc ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact
     3061 actagaaaaa agaaagtcga attttttact tttctttttc tcttttttgg ttagctgaca
     3121 cgccgcaaga ctaaagtcat ggaactctta ggtaatacgt cttaatgaaa acaaaaaaat
     3181 cccgcaaccc ctgatttcac aggatttgcg ggagtttttg attagtcttt gttcaagtcg
     3241 cgaagcaatt catcgatatg gttgccatag acaactgatt catcaagttc aaagaacaat
     3301 tcaggtgtct tataaatact tagattgtgc cctaactctc gacgaatcaa tcctgatgct
     3361 ttattcaatc catcttgtgc tgttttctta tctgatgcta agtcagataa aatgctgtaa
     3421 tagatcgttg cttgctgtaa gtcccccgta actttcacat ctgtgatcgt tacgttctcc
     3481 acacgagggt cacggacctt tttgcgcaaa atatcattga cttcttttaa gatttcttga
     3541 ccgactcggc ggtcacggta gttagccata atgattggcc tccttttatc agtttttagt
     3601 catttttgac ttcttccatg ataaatcctt caattacgtc atctactttg atgtcattga
     3661 atttttcaat cattgcacca cattcataac ccattttgac ttctttcacg tcatctttga
     3721 atcgtttcag acttgcaagt tggccttcat agattacgat tccgtcacgg attacacgga
     3781 caccgctatc tctacgaata tatccttctg ttacataggc acctgcaatc gtaccaactt
     3841 tagaaacttt gaaggtttca cgaacgatca tttgaccggt gattttttct tcaaattcag
     3901 ggtctagcat ccctttcatc gcagtttcga tttcttcgat ggctttatag atgatacggt
     3961 gaagacgaat atcgacttct tcagtatcag cttgcacttt tgcctgcggt gtaggacgaa
     4021 cgttgaaacc gatgataata gcgttgctgg ctgctgctaa ggttacatca ctttcattga
     4081 ttgctccgac agctgaatgg acgattttta cacggacacc ttccacatca atcttcttca
     4141 atgatgcagc cagtgcttct gctgaacctt gtacatctgc tttgatgatt acgttaactt
     4201 ctttcaattc gccttctttc aggctttcaa ataagttatc caaagtcaca cggcttgtgg
     4261 cagcacggtt ttctaataat gcacgtttcg cgcgttcttc acccgctgca cgtgctgtct
     4321 tttcgtcttc gaagactacg aaacggtcac ctgcttgagg tacatcattc aagccagtga
     4381 tttctactgg cgttgcaggt cctgcttctt tatcgcgacg gccaagatcg tttgtcatta
     4441 cacggacacg tccgtaagta ttaccgacaa cgattgggtc accaacatga agtgttcctt
     4501 cttggacaag taaggttgac acaggacctt tacctttatc aagacgtgct tcgatcactg
     4561 ttccgattgc gcgttgtgtt ggatctgctt ttaaatcttc tacttctgcg actaacagga
     4621 tcatttccag caattcttcg atgttttggc cgaatttcgc tgagatctca acaaagatcg
     4681 tttctccacc ccatgcttca ggaattaact catactcact taattcttgc ataacatgtt
     4741 gagggtttgc acctggttta tcaattttat ttacagcgac gatgattgga acgcctgcag
     4801 ctttggcatg gttgattgct tcaactgttt gtggcatgac gccatcatct gcagcaacaa
     4861 ctaagatcgt gatatctgtg atacttgctc cacgtgcacg catacttgta aaggccgcat
     4921 gtcctggtgt atccaagaaa gtgattggtt taccatcaat atcgatctgg taggcaccga
     4981 tatgctgtgt gattccgccg gcttcgccgc ttgttacacg tgaatggcgt aatgtatcca
     5041 ataaagttgt tttcccatgg tctacgtgtc ccataatcgt tacgactggc ggacgtgaga
     5101 ctaatttatc tggatcgact tcttctgcct cgaagaattt atcgatatca gcaatgtcaa
     5161 cttggacttt ttcttgtggt tccatgccat agtccgtcgc taacagttca atcgtatctt
     5221 tatccagtgc ttggttttga ttgaccatga caccaagcat aaataatttt ttaatgattt
     5281 ctgctggctc acgatgaatt tttttcgcaa tatctgctac gttcatacct tcagtatact
     5341 ctaatacatc tggcaattca cggaatttgc gtggtggtac agctggttta gttgattgtt
     5401 gctgtttgcc ttttttacct tttttattat aacgattacg gttattatta ttaaatttgc
     5461 cgcgattgtt attgtttggt ttgttgttat tgttagtacg gttttgattg ccgccttggc
     5521 tcgttccttg acgattttgg ctgctggtat ttcccgtatt attttggttt gttgttggtt
     5581 tttttccttg attcacttga ccgctccctt gaccgcgatc ttgataactg cggttatttt
     5641 tatttttttg ttgattgttc gttgtttctt ttttacgttg atcgttcggc tgttgattgg
     5701 ctggttttct gcttgcttgt tgtgcagctt gttgtttcgt gcttgggttt ttgaacgctt
     5761 gttgcaattt cttctcatca ttgctagtaa tcgcacccat atggtttttc acatcgatgc
     5821 caagttgttg tgctttttcc acgacgtctt tactagattt tttgagttct tttgctaatt
     5881 catagattct tttgttgccc atgcaatcac cttcctaacc ttcaattagc tccttggtct
     5941 tcttcgcaaa tccggcatcc attattccga ataccttgcg aggttttccg atcatctgcg
     6001 tgatttctgc ttcagaaaat agctcaaagc aaggaacttc ataatatgaa ctcttatctt
     6061 ttatcttttt tcttgtattc tcgcttgcat cggttgccac aaacaccaat tttgcttttt
     6121 gtttgcggat ttcagcaatg gtcagttctt cacccgtgat tagttttccc gcgcgcatcg
     6181 ctagaccgat gagattcatg gctttttgcc gattaactgt attcattttc caaataactc
     6241 tttacgtgct ttttggtgag tgacatagtc aagaagttct tgataaaact catctgttaa
     6301 tgttgtttcg agtactcgat cgagaatttt tttatcccaa gcttgttgta cttcttccgg
     6361 ctcaagtgag acatacgctc ctcgtccagg catttttcca gttggatcga tcgatacttc
     6421 cccttctttt gaacgggtga ttcggaccat ctctttttta ggtttcattt cacctgaaac
     6481 cacggatttg cgtaaaggaa ttttcctttg tttcatctct ttgcctcctt actaaagtta
     6541 agcttctggt ttttcttcga ccgtttcatt gttgaatgca attgtttcat attcatcgtc
     6601 tgttaaatct gactgaacga ttgcttcatc atgcagttct tctgtttctt tttgttgttc
     6661 ttgattttca taaaattccg tcatgtcaga ttctgatttg atatcgattt tatggttagt
     6721 caatttagca gctaaacgtg cgttttgtcc gcgtttaccg attgctagcg ataattggta
     6781 gtctggaacg acaactgtgc aggcctttgg atttgtctca tcgaagatca catccatgac
     6841 ttgtgcagga ttcaatgcat ttgcaatgaa tacagctgga tcttcattcc attcgacgat
     6901 atccatgttt tcgcctttta attcattgac gattgcttga actcgttgtc cctttggccc
     6961 gacacatgta ccgactgcat cgatatttgg atcatttgag cgaactgcca cttttgaacg
     7021 atcgccagct tcacgggcga tgctgacaat ttcaacgatt ccatcataga cttctggtac
     7081 ttcttgctca aataagcggc gcaataggtc tggatggctg cggctaacaa atacttgcgg
     7141 acctttagac gtattttcta ctcgggaaac ataaactttg attcgatcat gtggttgata
     7201 aaattcattt ggcatttgat cttgtttaga aagaactgcc tcaattttac caagattgac
     7261 ataaatataa cgtttatcct ggcgttcgac gattccttgc atgatgtctt tttcataagc
     7321 actgaattcg ttataaataa tcgttctttc tgcttcacgt acacgctgta aaataacttg
     7381 tttagccgtt tgcgcagcga tccgcccaaa atcttttggt gttacttcaa aacggatcgt
     7441 atcaccgatc tcatatgctg gattgattaa aagtgcatct ttcaatgaga cttccaactg
     7501 tgaatccatc acttcttccg ttacttcttt taccgcatag acatggatct ttcctttttt
     7561 ctgatcaaat tccacttcga cgttttgtgc ttggccatag tgacgtttgt atgcagaaac
     7621 caatgctgct tctaaagcat cgatcacgat ttcttttgag atcccttttt cagcttctaa
     7681 agcgtctaac gcatttaaca tttctttact cattttttct gattcctctc cgtgattaaa
     7741 attggatagc taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc
     7801 gtgtttttat gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt
     7861 catattgttt ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg
     7921 ccttttcata gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca
     7981 ggaaataagc ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct
     8041 cactgacaaa ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta
     8101 agaaccagct ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat
     8161 ctaaaatcgg tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct
     8221 ccttaaaaaa ttaagtgcgt aattccatta aaaagagtga gcgaaaaatc cgctcactca
     8281 cagttagtat cattacctat aagaactata ccatactctg cttaaaatta caagcagaca
     8341 ggaaaacaga tgcttatagc atatcgaata acgataattg attttcatct ggtagatctt
     8401 tcaatacgcc attgtcgttc atatattcga tcaatgtttt tgaaacttta ccgcgggtgg
     8461 caagatcttc tttggataaa aatggaccgt cttttcttgc ttcaacgatt tgttttgcca
     8521 cgttggttcc caaacttggg acagctctaa atggtgcgat caacgtatca ccttcaataa
     8581 caaagttaac ggcatccgat ttatacaaat caatcattcc aaatttgaat cctcgttcca
     8641 gcatttcatt ggctaactcc agcactgtca gttgattctt ttcttttacg gaagcatcta
     8701 atcctttgtc cgtgatttct ttcattgctt gtttcacagc atcttttcct ttgcacatgg
     8761 agactagatc aaagtcgtct gcacgtacag aaaagtatgc acagtaatac aaaataggga
     8821 aataaacctt gaaataagcg acacgaagag ccatcaatac gtaagctgca gcatgggctt
     8881 tcggaaacat atatttgatt tttgaacaag aatcgatata ccagtcgggc acattatttt
     8941 ctttcatcgc cgatagatag gtttctcgca attcatcagg gatcttgttc cattgtcctt
     9001 tacgaacagt ttccatgatt ttaaatgcca tcccgctatc taatccagca tggatcaaat
     9061 aaaccataat atcatcacga cagccgatta cttccgccag tgtcgcatct cctcgtcgaa
     9121 tcaattcttc cgcatttcct aaccatacgt ctgtaccatg agatagtccg gaaatttgca
     9181 gtagttctgc aaaagttgta ggatgcgttt cttctagcat ccctcgaaca aaacgagtgc
     9241 cgaattctgg aatacctaat gtccctgttt tggaataaat ttgttcctga cttactccaa
     9301 gtacttcagg accggcaaat atccgcatca cttccgggtc atccgtaggg atcgtttgtg
     9361 gatcgatccc tgataaatct tgaagcatcc gaataacagt tgggtcatca tgccctagaa
     9421 tatctaattt caatacatta tcgtgaatcg agtgaaaatc aaaatgagtc gttttccatt
     9481 ccgaattttg atcgtctgct ggatattgga tcggcgtaaa atcatagaca tccatataat
     9541 cgggaataac gatgatcccc cctggatgct ggccggttgt ccgtttgact ccagtagcgc
     9601 cttttgctaa tctgtcgact tctgcacttc gaaactgcag attattgtcc ctttcgtatc
     9661 cttttacata gccatatgct gttttgtcgg cgactgtacc aatcgttccg gcacggtaaa
     9721 catagtcttc gccaaacaat actttcgtat agttatgggc ttctgcttga taatcacctg
     9781 agaagttcaa atcaatatcg ggcactttgt ctccatggaa tcctaaaaat gtctcaaatg
     9841 gaatatcatg accgtctttg tttaagcgtg caccacattt tggacattgt ttttctggca
     9901 tgtcaaatcc agaaccatac gtaccatctt caaaaaactc ggaatattgg cactctggac
     9961 aataataatg aggggctaac ggattaactt cagtgattcc tgtcatcgtc gcaacaaagc
    10021 tagagccaac agagccacgt gaacctacta gatagccatc ttcattactt ttatgcacta
    10081 gtttttgggc gatcagataa ataaccgaga agccattacc attaatagaa ttcaactctt
    10141 tttttaatcg tttttgaatg atctcaggta acggatctcc gtacatttgt tttgcttttg
    10201 tgtaactcaa ttctgatatt tcatcttctg aacctggaat cttcggtgta taaagttcat
    10261 ctttgactgg aatcacttct tcgcagatat ctgcgatttt attcgtattt tctactacga
    10321 tctctttcgc tgtttcttcc cctaaaaagt gaaatgcagt tagcatctca tcggttgttc
    10381 ggaaatggac atccggcaaa ctatgacgat tcaacggatt cgctccgccc atagaattga
    10441 tcaaaatttt tcggtaaatg gcatcttctt cgttcagata atgtacatta cctgttgcaa
    10501 caacgatttt atccaaactt tttccgattt ctaccaaatt ttggataatt tcttccaaat
    10561 catgttcatt ttttaccaat tcttgctcga tcaaaggcgc atagaccgct tttggcataa
    10621 cttcaatata atcgtagaat tttgctcggt ttcttgcctc ttctacccct ttttgcatca
    10681 tggcttcgaa tatttctccc ttatcacaag ctgagccgat caatagattt tcacgcatct
    10741 ttttcaattg ggagcgtggt attcgtggga cgcgttcgaa gtattcgaca ttcgacattg
    10801 aaatcagttt gaacaaatct ttcagtcctg cctgattttt tgctaaaatc gttacatgga
    10861 aaggtcgagc ccttttgtaa gaatctcctt ctccgatatg ctcatttagc tgatcatgat
    10921 aaagcatgtt atgattgtcc attgcctctt tcacaaagat ccatgctaag tgaccagttg
    10981 cttcagcatc atagattgct cggtgatgct gttccaagct gacaccaaat tttttagata
    11041 acacacctaa tccgaaacgt ttgaattgag gatacagata tctagctaat tccaacgtat
    11101 caatgactgg attggccgct tcaggaatac cataccttgc gtagctagta ttcaagaacc
    11161 ccatatcaaa agccgcgttg tgggctacca aaattgtatc ttttgaaaat tcaaggaaca
    11221 tccgcaatac ttcttcttcc gactttgatc ctcgaaccat tccatccgtg ataccagtca
    11281 gatctaccgt tgttcgtgac aaaggatgtc ctggatcgat aaattcatca aagctttcga
    11341 tcacatttcc tttatacatt ttgactgcgg ctagctcgat gatcgtgtca tatactgcag
    11401 acaatcctgt cgtttccacg tcaaatacga catatgtggc ttcactcaat gcttcatgtg
    11461 catcattata agcaattggg acaccatcat ctacgacatt cgcttccacg ccgtataaga
    11521 ttttcacacc tgcttttttt ccagcactat gtgcttccgg aaaggcttgc gcaccaccgt
    11581 ggtctgtaat ggcgatagct cggtgtcccc atttccctgc ttgtgccaca agatcagaga
    11641 tgctgtttgt tgcatccatc gtactcatat tgctatgaac atgaagctct actcgttttt
    11701 ccccttcagg agcataatct ttgcgaggtg tatgtttgac ttctatgata tcttgcgcat
    11761 tcatgaccaa atcacggaca aacgtatctt cttgaatact tcctcgtacc tttaaccagc
    11821 taccgacact gatcgcatca aatacttgtt catctttttc gccgttcgag aattttttga
    11881 cgataaatga tgaagtataa tctgtgattt tcaaagtcaa gatcttgcgt tttgaacgta
    11941 gttctctgac ttctttgtcg aatacgtacc cctcaagtgt gactcttcgt tcttcttcaa
    12001 cgatactgat cattggtgtc gttggttcat cggctggaat atttcgtcct agctggatgt
    12061 ggatgggtcc ttcaagagct ggcgattgct cttttctttc ctttttcttt tgttcgtgga
    12121 caactagact ttcagctgct tgcttcataa aggcttctgc ctgttcttgt ttgcgttctt
    12181 caaaaagttt caatactcgt tccgcttgct gctcatccac ttctggttcg atacgaaatt
    12241 ttgggaatcc gtaactgacg aacaactctt ctactaatgg caagtattgt tgcttcaaat
    12301 aagaaatagc tcctgtactg tcgattggca agatgacttt acgatctttt atcacaggta
    12361 cctgcgtttt caatacttgc tgtgctagtg gtgtatcgca ttgctgattt tccaaagctt
    12421 gggcccagta atcttgcaag agctgttcat cgaatgtctg gtcatctgct aagatattca
    12481 gtttgacttg tgcaatatct ttaaaagcga tagtcagatg ctgagtcaat gaccgatata
    12541 gcataatagg caaaattttg gaaaaatgca gcgtaaattc ccataaacgc gatttacgat
    12601 ggaccactac actatccatt tcaccagcag taagcagtgg atgatttttt tctgcttcct
    12661 ctagttggat ttgttccaac agtttttcaa ataaatctcg tttttctgac aaagatatac
    12721 gccctttctg atgagaaaca atgcaattga tcgcatctta tcctcttctt tttcagtacc
    12781 ttttagtata ctcgtttttt ctgagtttta cattaaaaaa ttggaactgc gattcaaatc
    12841 gcagttccaa ttttaaaagc gaatcatcag attgtcaaaa acagctgatt cagctatttt
    12901 tattttctgt gttttaacgc ttattattcg ccttggttca agaggattgg taaagtattc
    12961 accaattctt ctttacgtac ttcaaccatt tcgccagttt tcttgatttt cacttctacg
    13021 attccatcca ctgctttttt accgacagtg attctgattg gacagccaat caaatcagaa
    13081 tccgcgaatt tcactcctgc gcgttcattt ctgtcatcaa ccagtacttc atagccagct
    13141 tttgtcatcg cttcttctag ttcattcgtc aggtttgttt ggtattcgtc ttttagattc
    13201 atttggacga tatgcaaatc aaatggcgca attccttttg gccagttgat tccttgttca
    13261 tctgaatgtt gttccacgat tgctgataat aaacgactta caccgatacc ataacagccc
    13321 ataatcacaa atttttctcg tccattttcg tctagtacag ttgctcccat agattcactg
    13381 taacgagtgc cgattttgaa gatatgtccg atttcgattc ctcgagtaaa ggcaagaaca
    13441 ccattgttgt ctggtgaagg atctccttct tgtacaaaac gaagatcttc ataagaaagt
    13501 acagtgaaat cgcgttctgg attcacattt ttatagtgga atcctgtttc gttcgctcca
    13561 gtaatggcat tcgctaaatc ttggacataa cggtctgcat atacttttac gtcatctgaa
    13621 acaccgactg gtccgacaga accaaactca gcacctagat atttttgtgc ttcttcttct
    13681 gttgcttctt ctaaaaagtc agcagataaa aagtttttca gttttacgtc attgacttca
    13741 tggtctccgc gtaccaaaac aaggacaggt tgttcatccg caatgaacaa tacagacttg
    13801 atgatttttt gaggttcaac agaaaagaaa tctgctactt cgtcaattga ttttacgtta
    13861 ggtgtagcta ctttctccaa ttcaagctgt gtttcatgcg atttttttga tacatagtag
    13921 cttgtagcca tctccaagtt tgcagcataa tcactttcag tcgaataaca gatcgtatcc
    13981 tccccgattt ctgagatcgc catgaattct tttgagtctt tcccgcccat tgcgccaccg
    14041 tctccgataa tcgagcgaaa ttctaagcca caacgcttga atacttcggt gtaggctttt
    14101 tcgtaatctt tatatgtctc gtccaaactt tcttccgttg catggaaaga atacgcatct
    14161 ttcatgataa actctcttcc gcgaagcaaa ccgaagcgag gtcgtttttc gtcacgatat
    14221 ttaggttgga tttgataaag atttaaaggt aatttcttat atgaattgat ttcattacgc
    14281 atcaaatcag taaaagtttc ttcgtgagtt ggtccaagga tcatttttcg atcattgcgg
    14341 tctttgaaac gatacaagtt tggtccatat gtttcgtaac gcccggattc ttcccaaagt
    14401 tctgctggca agatggcagg catcagcatt tctaccgctc cgattttttc aaattcttcc
    14461 cgcataatgc gtttcagttt ttccaataca cgatttgcta atggcagata tgaataaata
    14521 cccgctgata cttggcggat atatccagct cttagcaaga tttgatggct taatacttct
    14581 gcatcatttg gaacttcgcg taatgttgga atcaacattt ttgattgtct cattctatat
    14641 actcctttat ttcctcaaaa tagttatcgt ttgttattat accctatttg tcaacttttt
    14701 ctagaaaaag aatcgttgaa tatcgttcca tgtaactagc accatcaaca acattaaaaa
    14761 tccaaagcca gctaatgtca atattccttc tttttcttga cttaatggtt tcccgcgaat
    14821 cccttcaaaa atattcaaga ctaatttccc gccatctaag gcaggaatcg gaagcagatt
    14881 gacgattccg agattcattg aaagaagcgc catcaaacta ataacagttg ttacaccttg
    14941 atttgctgct tctgaagaca attggtacat catgacaggt ccgcctaatt tatctaaact
    15001 gaaacctgta aatagtgatc ctaaggcttt gaaaatttcc aatgaaccgc tgaaagcttg
    15061 acgcgtccct ccaatgatct tatccataaa acctgtattc attggggctt ttataccaag
    15121 ttggccaact ttttcgccat ttgactctac agatttcggt gtcacgtcga cagattgcac
    15181 ctgaccttct cgttcgatct taaagtctaa tgttttatcc ggatttttcg taatgactgt
    15241 tgtcagatca ttccatgaat ggatttcttt tccgtccaca ctgactacct catcattttc
    15301 ttttaagcct gcttctgccg cagctccatt aggcatgatc tctcctacgc gattagtgtt
    15361 cgtcacttga acaccacctt gcataaatgc cagaatgatg aataacagga ttgccaaaat
    15421 aaagttattc atgggtccag caaagttggt cagcatacgc tgccacaatt tagccgattg
    15481 gaactgtacg tcttttggcg caattctgat ttctgttccg tcgttttcaa taatcgtcgc
    15541 atcgtgatca acagggtagg ttactacttc tgtttcgtct ccattcacat aaccagtgat
    15601 agtcagctca tcttctaaat cataacggct caattccatc gggatagcat ttgtcaattg
    15661 gattttctta cttaaattta tcttctctac gatgccgtca gaatttagta aaagagaaag
    15721 aggcattcct ggtgccattt ctgtttcatc atccccattg cctgccattc gaacataacc
    15781 gccaataggt aataggcgaa gcgtatatgt tgtcccgtct tttgcttgat gcccataaat
    15841 tttcggaccc ataccgatag caaattcgcg aacgaggatt cctgatcgtt tcgcaaagaa
    15901 gaaatgacca aactcatgaa caatcactaa tataccaaaa acgatgataa atgtcagaat
    15961 cgttttcata gcttttttct cctttacttg ttttttgtgt tttttataaa acaacgataa
    16021 aacactataa ttttaccata gtataccaaa gacaccaata gtatcaatat aatgaaaaat
    16081 aaaaacctgc gtcttttatg aaattcacaa agaaacgcag gtatacttac taaataatgc
    16141 caaataaatg catgatagga aatacaaaca gcaaactgtc gaaacggtct aagattccac
    16201 catggcctgg taagatattt cccgagtctt tcacatcata atgacgtttg attgcagatt
    16261 cgaccaaatc accaaattgt ccgactgctg aaaaaataat cgtcatcaga agcatgacaa
    16321 acataccatg attaaatagt tcttttgctg ggtatagcaa taaataaaga aatgcgacta
    16381 caacagcact accaatacca ccgagcgcac cttcaatcgt tttgttgggc gaaatatcag
    16441 gacttaactt atgctgacca taacgtcgac caaccatata tgctccgata tcagttgccc
    16501 aaacaataaa tagaccaaat atcaaaacag ccaagctttc tgttcgtgca ttgacaaaat
    16561 tctggaaacc tattcccaca tacaagctga caagcacagg aaaacctgct tcatcaatcg
    16621 tatacgtatt tttagaaata actgatgttc ctaaaagaat cataactata agataaaata
    16681 acataaatgt acttacattc tctggaagaa agaaaaacca tctttctttt ggcaaaacaa
    16741 gtaacactgc accaacggcg gataaaactc cttcaaaact taagagtgtc aatcctttca
    16801 tccgaaacag ctcgtaaact cctattactg ctaagattgc tgctgtaagc tcaaccgcta
    16861 tgcctccgat ccatataatc ggaataaaca agactagcgc cacggctgct gtgaccacac
    16921 gttgtttcat gactgatccc ctttctcatc ttctgttttt tttacaccgc cgaatcgacg
    16981 gtctcgattt tgataagagg cgattgcttc ttcaagatgc gcaccatcaa aatcaggcca
    17041 aagcgctttt gtaaaataca gctcactata tgcgatctgc cataacagaa aattactaat
    17101 tcgctcttct ccacttgtac ggatcatcag ctcaggatct tgtaactctt taggcaagaa
    17161 acctgtcatt aaatgcttag caatcaattc atcatcgatt tcttctgcgt gtatttctcc
    17221 ttttgctact tcttcggcaa tttcttggac agcagtcacg atctctgctc tgcttccata
    17281 attcaaagca aaattcaata ccattccagt attgtttttt gtttgctcaa ttgcacgtct
    17341 tacagcatct tgcgtatgtt ctggcaatac gttttcataa cccatgacat gaactttgac
    17401 attttcttta atcaattctg gtacgaacgt atcaaagaag tcgacaggta gttgcatgag
    17461 aaaacttact tcatcttttg gtcgcttcca gttttcagtc gaaaaggcat aaagcgtcaa
    17521 cactttcact ccaagccttg atgctttttt tgtgactttc tttactgttt ccatgccttc
    17581 tttatggcca gcaactcgtg gcaaacgacg gttttgcgcc caacgaccat tgccgtccat
    17641 gatgatggca atgtgctgag gaattggtcc atcggtatta aattgaaatt cgcttttttc
    17701 ttgaatatat ttgttttttt gcggaaaaaa acgtaacatt ctttttcctc ctatacttaa
    17761 aagattccca ctatcttaag tattatagca atatctaact gtttttccta tgaaatcatt
    17821 gtttttttat ttaaaaactg aataattttt tcttttttta atttttaaat aaaagaaata
    17881 taaataaaaa cagaggaagc ggaatgatcc gcccctctgt ttttatgatt ttattaaact
    17941 tccaataatt ctttttcttt atcagcagcg atcttatcta cttctttgat gctgttatct
    18001 gtcaatgttt gtacgtcttt ttctaatccg cgcaaatcat cttcggtaat atcaccattt
    18061 ttttgttgtt ttttatattc atcgatcgca tcacgacgga tgttacgaat cgcgattttt
    18121 gcattttctg cttctttttt aacatcttta gctaattctt ttctgcgttc ttctgtcagt
    18181 tgcgggataa ctaagcgaat gacatttcca tcattggttg gactgattcc gatatcactt
    18241 gccataatag ctttttcaac atcttgaaga atgctcttgt caaaaggtgt gatcattaaa
    18301 acacgtgctt ctggaatttg gattgatgcc atttggttca atggtgttgg cgcaccgtag
    18361 tagttcacag taatacggtc caaaaggcta gcgttcgcac ggcctgcgcg gatttgccca
    18421 agttcacgtt gaagattttg tgctgctttt ttcatttttt cttttgcttc tgtcataatt
    18481 gcatctgcca tttttatttc ccccttacag ttgttccgat attttcgcct aagattgcac
    18541 ggcgaatatt tccgtgttca tttaaattga agacaagcag tggaatatca ttatccatgc
    18601 ttagtgaact tgcagttgaa tccatgactt gtaatccttt ggcaataact tccagatgag
    18661 tcagttcttc aaattttact gcatttgcat ctactttcgg atcagcagaa taaacaccgt
    18721 ctacattgtt tttagccatc aggataacat ctgcgccgat ttctgccgcg cgtaatgctg
    18781 ctgttgtgtc tgtcgagaag tacgggttgc cggtaccgcc tgcaaagata acgatccgtc
    18841 ctttttctaa atgacgttct gctttacggc gaatatatgg ctctgcgatt tgacgcattt
    18901 caatcgaagt ttgcacgcgt gtcggtacac ccacgttttc caacgtatcc tgtaaagcta
    18961 aggcattcat aactgtagct aacataccca tgtaatcagc ttgagcacgt tccatgccca
    19021 tttgtgctcc gatttgtccg cgccagatat ttccgccgcc cacaacgatt gccatttcaa
    19081 cgcccagctc gtgaacttct ttgatttctt ggatgatttc tttgattact ggtggtttga
    19141 ttccaaatcc tgcgtcccca gctaaagctt ctccactcaa ttttaagact acacgctgat
    19201 atttcggtgt gaccatgttc attcctccaa tattttctat tgccatttta ccatacttag
    19261 atgatttcga cactctaaga ctggtttttc ttgttttgct taaaaaaagg gagcgcacaa
    19321 accgtgcgtt cccgtctgtt attcaacaga attatttttt cacttggctc ataacttctt
    19381 ctacaaagtt atcttcgcgt ttttcgatac cttcgccaac ttcgaaacgt acgaatgttt
    19441 taacagttgc gccttttgat gcaacgtatt tttcaacagt catatcagga tctttaacga
    19501 atggttggtc caccaaagcg atttctgctt tgaatttctt caagcgtcct tctaccattt
    19561 tttcaacgat attcgctggt ttgccttcgt tcaatgcttg ttctgtaaga acagtttttt
    19621 catgttctaa ttcagcttct ggaatttgtg attcgtttac ataacgagga ttgatagctg
    19681 ctacgtgcat agctacgtct cttgcaactg tttcgtcagt tgttccatct agaacagtca
    19741 atacggcaat acgtccgccc atatgcaagt atccaccaaa tgcagcattg tcgtcttttt
    19801 ctacaacttc aaagcgacgg aagctgattt tttctccgat aacttgagtt gcttcgatca
    19861 agtcagattc aattgtacct ttatctgttt tgattttcat tgcagcttcc atgtctgctg
    19921 gtttgttttc agcaacaagt tctgcaattt cttttactaa atctttgaac atttcgtttt
    19981 tagaaacaaa gtctgtttct gagtttactt caacgattgc tgcagtgtta cctttcacag
    20041 caactgaagc caatccttca gctgcaatgc ggtcattttt cttcgcagcc tttgccattc
    20101 ctttttcacg taaaagatca actgcttttt ccatgtcgcc ttctacttca actaatgctt
    20161 ttttcgcatc catcattcct acgccagtca tttcgcgtag ttcttttacc attttagctg
    20221 taacgtctgc catgtttaac tcctcctgtg tgtttttctt tttaaaaaaa gctgcttcaa
    20281 aggagagtga ggcttgtcgc ccagcctttg aaacagctcc atcattcaaa attattctgc
    20341 tgaagaattg tcgccttcaa caacatctac gatttcttcg attgatgttg ctgtgttttc
    20401 ttctgtgaaa tcttcttcaa ctacttgatc ttcaccttgg tttccttcga tgaaagcatc
    20461 agccattttt gaagtaatca atttaacggc acgaattgca tcgtcgtttg aagggattac
    20521 tacgtcgatt tcatctggat cgcagtttgt atcaaccata gctacgattg ggatatttaa
    20581 tttgtgtgct tcttgaacag caatacgttc tttacgtggg tcaacgatgt acattacatc
    20641 tgggattctt ggcatatcag cgataccgcc taagaatttt tcaagacgtt cacgttcttt
    20701 gttcaaacca gcaacttctt ttttaggtag aacttcaaaa gttccatctt cttccattgc
    20761 attgatttgt ttcaaacggc tgatacgttt ttggatagta tcccagtttg tcaatgttcc
    20821 gcctaaccaa cgatggttaa cgaagtattg tcctgcacga gttgcttctt ctttgattgc
    20881 ttcttgtgct tgtttttttg tacctacgaa taatgctacg ccgccttctt cagcaacgct
    20941 cttcatgtaa tcataagctg catctactaa tttaactgtt ttttgcaagt caatgatgta
    21001 gattccgttt ctttctgtga agatatattt cttcattttt ggattccagc gacgagtttg
    21061 gtgaccaaag tgtacgccgg cttctagtaa ttgtttcata gaaattactg ccatgtttgt
    21121 ttcctccgat ttggttttat ttttcctctt cttatcttct accttgccgg caaacttttt
    21181 caagcaccta ccgacaatcc aataagaatg tggatttgct gatgcataaa gcaccctcag
    21241 ctattataca gacaaaagat ccgtatcgca agagcaaata tacttttctg ctcaacattc
    21301 aatagtttac ctgaaagata aaaagaattc aagaaaaaca gtagatttct ctttgtttct
    21361 ttattatcct ttttccataa aataatttta ggtataaaag acgaatatta ttgggcaatc
    21421 cttctttttt ttgttatgat acatgtgaaa tctttcgtaa aggagaaaga aaatgcgcaa
    21481 agctcaaaga catttgctga ttaaacaagt cattgaagaa ttcccgatcc gtacgcaaga
    21541 agaactatta aacaaacttg ggcattatgg cgttaccgcc acgcaggcaa cgatttctcg
    21601 agatatccgt gatctaaaaa tcgtgaaggc acctgatgaa aatggcgttt cccgcttcgt
    21661 attgtttcgc gaaaaaggaa ctcctgagac taggactgag gaagaggatc ggctggttca
    21721 aatgattgaa gacattgtat tgaaagtcga acgagtccac tttttgacga tcgtcaatac
    21781 cttgccagac aatgctcatt tatttgcatc tgttttagat gagatcaaac ctccctctat
    21841 tgtcagtaca attgctggat tcgatacgat catggtcatc tcggaaaatg aggaggacgc
    21901 aaaacgagta gaagaatttc ttcaccatcc aactgaagta tcactttttt aatcagagca
    21961 cgtattccta atatggaatg cgtgtttttt tattttcaat attttcctta ttgaataaac
    22021 ctttacactc tttacaaaaa tacatcattt tttattcaaa tttttcaaca ccttgattga
    22081 atcacaataa tcatcattta tattggatgt taacaagagc agcttcttgc tctttgtgta
    22141 tttcaaaaaa gaaatgaaag gaaatcatat gtataaatta ttaacttctg gaccattgac
    22201 gacttctgaa acagtgaaaa atgctatgct gatcgatcat tgtacttggg atcaagaata
    22261 caaagaaatt acacaatgga taagaaaaaa attattggat cttgctcaag tatcggaagg
    22321 aatatacaca acggtcttaa tgcaaggtag cagctccttc ggggtagaat cggtattaag
    22381 ttctgtgatc aggccagaag atactgtact gatttgttca aacggcgcat atagacaacg
    22441 aatgatcaac atgtgcgaat gtctgaaact gaactatacc gtttatgagg tatcggaaca
    22501 tcaaatcctc caagctcatg tgattacaca gctgattgaa gagaatccgt ctatctccgc
    22561 actagcaatg gtccatagcg agactacttc cggtattttg aataatttgg aagagattgc
    22621 tgctgtcaca caagaaagag atcttttgtt tatagtggac gcgatgtcaa gctttggtgg
    22681 gataccgatt tgtgtagccg aactagggat tgattttttg atttccagct caaacaaatg
    22741 tattcaaggt gttccaggct tttcttttgt acttgctaat aaagcggaac tggaaaaacg
    22801 aaaaaatgtt agccgaagtt tgtcacttga tctatatgac cagtaccgcg tgatggaaaa
    22861 cgagaatggc aaatggcgtt tcacttcccc tacccatacg gttttggctt ttcaacaagc
    22921 gctgaaggaa ctagaggcag aaggaggaat cgaaactcga tattcacgtt atctcgccaa
    22981 taatcatgtg ctacgacaaa aaatgacaga gatggggttc cagcctttca ttcaagaata
    23041 tcaggggcca ttcatcacct cttttcttta ccctaaggac tggcgatttg attttaatca
    23101 tttttatcag tatttaaagc aaaatggatt tgtgatctat cccgggaaaa tcagcgatca
    23161 tgaatgtttt cgtatcggaa atattggcga gatctatccg gaagatattt tggaactgac
    23221 agcaattatc aaagactata aggagaacgt taatgattaa aactgtaatt tttgattggg
    23281 caggaacaac tgtggacttt ggctgtatgg ctcctgtcca cgcttttaga aatgcttttc
    23341 tagaaaaagg aatccaactg actgacaaag aaatccgcta accgatggga aaattaaaat
    23401 gggatcatat ccaacagctt ctttccctcc cttctgtcaa aaaacaatgg atagctattt
    23461 atggacaact acctcaggaa aaagaggtgg aggaattgta tcaacaattt gaacattatc
    23521 tgtttaaaga tttggtcaag cattctacct tgaaacccga cacattggaa acgatcgaac
    23581 ggttgagaaa cgctgggatc aatattggtt ccacgaatgg atttaatgct cctatgatga
    23641 caatcgtagc agaaaccgca aaaaaagaaa ggtattcacc agacttcatg gcaacttttg
    23701 aagacgtcga agggtatggt cgaccgtttc cttatatgat ccataaaaac atgcagtact
    23761 tcaaaaacaa gtcggttgat gaagtaatca aagtcggaga tacggtctca gatatccagg
    23821 aagggaaaaa tgccggagtg ttgacagtag gtgtaattga aggtagttcg ctaatgggga
    23881 tttcttatga tgagtaccaa aaattagaga tggggaaaaa gatcgtttaa aacagtctgt
    23941 tgctcttaga ttccaacaag ccggcgctga tatttgtgta aacaatttaa aagagttaac
    24001 agaatacatt ttgtacgctg acatgaatcc agaatgactt ttatacaaaa taagaggttg
    24061 tgaaaaagct gtcctgtatc aagtaataaa aacagccaag caaaaatagc tcctcatatt
    24121 tttcgtttgg ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    24181 aaaaaaggga gctgtgacac gacttttgtc acagtcccct tatttgcaaa caaacagtgt
    24241 ttaagagaca acctctccac taaacggtgt tcattcagct gactctcggt atttgctcaa
    24301 aaaacgataa aatttgaaaa gctattttct cttttgtttc tctaatactc ggatcagaac
    24361 gctgatttca cattctcttt ttcttacatc ttatctggtg catgaagtcc tagcaaacga
    24421 aggtcttctt tcaataatac agtcactgca taaactagag ctaagcgtgc ttctttttgt
    24481 tcatcatcag ctaaaatctt cgtatgagca tagtatttgt tgaatgcttg tgctaatttg
    24541 attgcatgtt tcgcaatcac tgacggttcg tatttttccc cagcagacaa gaccgtttca
    24601 gggtattttt gaactaattt aaccacttcc cagctggtat cgtcattcaa tgcatagtct
    24661 gctgtttctg aagggacaaa tcctgctttt tccaacaggc tgactgcacg agcatgtgta
    24721 tattgcacat aaggtccagt ttctccttca aatcgaacaa cttcttccag gttaaagtca
    24781 aatgtattca gtcgatcgtt tttcaaatcg tggaaaatga ctgccccaac cccaacttgt
    24841 ttagctacag catctttgtt ttccaaatca gggtttttct cgctgatttg ttctttagca
    24901 gattggattg cttcatttaa tacttcttct aataagacga tctttccttt acgagttgat
    24961 aattttttac caccttgcgt gatcaaacca aatggaatat ggtgcatgtc gtcagaccag
    25021 tcaaagccca tttccttcaa gacagctttc aactgtttaa aatgatagct ttgttcattc
    25081 cctactacat atagagattg tttgaagtcg taagtacgtt tacggtacaa tgcagcagct
    25141 aagtcacgtg taatgtatag tgtcgcaccg tctgacttct taatcaacgc tggattcagg
    25201 tcataagcag ataggtcaac gatctctgca cctttatcct cgttcagcaa atgtttttct
    25261 tctaaaagtt tgacgatttc atccatcttg tcattgtaga aagcttcacc gttcaacgaa
    25321 tcgaaacgta cttccagcag atcatagatt ttattgaatt ctttcatcga ttcatcacgg
    25381 aaccattgcc ataattgaat agcctcttta tcgccttctt ccagacgttt gaaccaagca
    25441 cgagcttctt catttaattc tggttctgtt tcagctactt catggaattg gacgtataaa
    25501 cgaagcaatt cattgattgg ttctgcttta acagcttctt ctgtacccca ttttttgtaa
    25561 gcgacgatca gttttccaaa ctgtgttccc cagtcaccta aatggttgat gcggattggc
    25621 tgataaccga ttttttccat aatgaaaccg atcgaattac cgataactgt cgaacgcaaa
    25681 tgtcccattg agattggttt ggcaatatta ggagaagaca tgtcgattgg tactgttcct
    25741 tgattcccga tgttgctatc cccataatgt tctttttctt tcactactgt ttgcaaaact
    25801 tttttgctga taagttcttt attcatgaaa aagttcaagt aaggtccgac aacttcgatt
    25861 ttttcaaagt tggcagaatc gattttttct gctaaatctg cagcgatttg ctgtggcgct
    25921 tttcggtaaa cttttgctaa tgaaaaggct ggaaatgcaa catctccgtg ttcagctgat
    25981 tttggatttt ctagtaattg ctcgacttgt tccagtgtta aatcatcttt gacagcgtca
    26041 tagacagctt ttgcgacaag atctttatta ttcatcttta ttcctcctaa agtgttccct
    26101 tgattgttaa acaaaaaaaa tctctagcga cggcatactt agtatgccat cactagagac
    26161 gagatttccc gcggtaccac tccaattgtc ctaaaaaagg accagctcca tctgatatcg
    26221 gtagacgacc gtctgtttaa aacagaattc tccaagtgcg cttcgttgta tcttcttcat
    26281 tcggcttcca ccacttccga attcgctagc caagaatgat acaagtactc tcttgttcaa
    26341 caaatcttag tcttattaaa ctttcttgaa ttatatcaga aaaaaaaacg aaaggctagt
    26401 cgtttcataa aaaaacaatc cagatggcct aaaggagaag aaataccacc tggatagcta
    26461 taaatcattt cgtaaatacg aaagacttaa caaattaatc agctacgata atcgttcctt
    26521 cttcagaagc taaaagattc tcgatatttt ctaaagaagt gatgattgcc ttagcgtttg
    26581 gttttgcttc aacaaatgca atagctgctt ctactttcgg aagcatgctt cctggagcga
    26641 attgcttttc atcaatgtat tgtttcattt ctgaaacagt aacagtttct aatttctttt
    26701 gatctggttt ttggtaattg acatacacat tgtctactcc tgtcaatacg atcagcaaat
    26761 ccgcatcgat gatttcggct aatttttctg aagcaaaatc tttatcgatt acggcttctc
    26821 gtccttctaa tccagtagct gtttctacaa caggaatccc accgccacca acagagactg
    26881 tgataactcc ttgatcgacc agcgtttcga tgacacgtgc ttctttaatc gagatgggtt
    26941 taggggaagc gactactttt ctccatccac gtccagcatc ttctttgaat gtcacagtgg
    27001 agtcagcatt catttgttct ttggcttctt cttccgtgta gaatggaccg actggtttac
    27061 ttggattttt gaatgaagga tcattttcat ccacaataac ttgagtgact aaagaaacca
    27121 catctttatc gatccctttt tccttcagta cttcgcccat ggcgttttgt aaccagtaac
    27181 cgatagatcc ttctgtcatt gcaacacatg tatctaaagg cattgccggt gttttctcag
    27241 aatcagcagc ttgctgctga atcaataggt taccgacttg cggaccattt ccgtgggaga
    27301 tgatcaattc atctccttgt tcgataaatt tcactaaata ctttgctgtt tccattaacg
    27361 cttcttgttg ggcttttgca cttgcatccg tagacaagat ggcattgccc cctaaagcga
    27421 caactacttt tcgtttggcc atttcattcg tcctttcttc agttctaccg aattttctag
    27481 ataacaaaac gagccagcgt tttgtgattt tccctcaatg ctgactcgtt ttttcgtgag
    27541 atgaatgtgg ttatgcttaa acgcgaggga taaacaagtt acctaatgtt gctgccatga
    27601 tcgctttgat tgagtgcata cgattttctg cttggtcaaa ttgacgagca tatttgctgc
    27661 ggaagacttc atctgttact tccatttcag tgatgccaaa gcgttctttc atttgttcac
    27721 cgtaaacagt gtttgtatca tggaaagctg gcaagcagtg caagaagatc aaacgatctg
    27781 tgttgtgtgt tttttctacc atttccatat tgatttggta aggtttcaac aatttgatac
    27841 gttcttcgaa tttatcttct tcacccattg atacccatac atcagaataa aggacgtctg
    27901 ctccgtctac acctttatca acatcgtcgg taatcatcaa ttgtgcaccg gatttttcag
    27961 caaagccttc tgccattttg acgatttctt cttcaggttg taattctttt ggtgcaacga
    28021 tacgcatatt cgctcctaaa attgcacctg tgactaataa agagttagcc atattgtttc
    28081 gaccatctcc gcagtaagca acagtgatac cttctactgt tccaaagttt tcttggatag
    28141 ttaaaaagtc agcgatcatt tgtgttggat gccattcatc agtcaagcca ttccaaactg
    28201 gaacaccaga gaattctgct agttcctcta ccattttttg actgaatcca cggaattcga
    28261 ttccgtcaaa catacgtcct agtactttag ctgtatcttc tgtggattct tttttaccta
    28321 attggatatc atttgcacct agatattcag gatgtgcacc tagatcgatc gctgcagtag
    28381 taaatgcaga acgagtacgt gtagatgttt tttcaaataa aagcgcaata ttttttcctt
    28441 ctagatagtg atgtgggata ccacgttttt tcaagtcttt caagtgttct gaaaaatcga
    28501 tcaaatattg taattcttct tttgtaaagt ctttttctgc taataagctt cttccttgga
    28561 atactgattc tttcatatta aacattctcc tttagattgt ttttatttaa gattaaagag
    28621 gaaatcccga cggcagctga cagtaagact gccgtcagga aacaaattac ttcaagtctt
    28681 cacggacaag tggttggctc atgcagcgtg gaccaccacg acctcgtgac aattcacttg
    28741 aattgatttc taacactttg atgccatagc tacgaagcaa ttcgttcgat acataatttc
    28801 ggttataagt gactacaaca cctggagcga ttgccaatgt gtttgatcca tcattccatt
    28861 gttctcgagg tgcaacgatc tcatctccat taccagttgg gatcagtaca agatcatcta
    28921 atccaagagc agctttcatc gtttcgtgta agttatctga atgagtaatc ttgatatcat
    28981 caccatctgg ttcgattgta aagacatcca tcttaccgtc tttactttga attgctggat
    29041 ggatagtgaa tttatcgtga tctaccattg taaatacggt atccaaatgc atcattgcac
    29101 ggttgttcgg aattttgatt gccaacactt tttcaaatcc tgaatttttt gcgaataggt
    29161 ggcgtgctaa tttttctaaa gctttcgcat tagttcgttg agaaatccca acagctacta
    29221 ctttatcgct taagatcaat tcgtctccgc cttcgatatg atctggattt tcacgatcca
    29281 accatacttc gattccttta tttgcaaatc ttggatgatg tttcaaaata tattctgtaa
    29341 acatcgattc acgacgacgt gcttcaaaag tcatcttatt gactgtcatc ccatttccca
    29401 ttgatgcgga agggtcgcgt gtaaagtaca agtttggcat tgggtccatg taaaatggat
    29461 agtcatcgtc tgctgacaga tcatatagac tgctagaacg tacttcgata tcttttgtac
    29521 gaaccccagc catgatttta tctaccattt cttgcgtttc cattgataga aggaactcat
    29581 gaagaccctc tcttacagca ttcgatgcaa tatgagattc atccaacatt ttattcaaga
    29641 attgttcttt gacattgcct gcgtcaatcg cttctgccgc taatttttcc aagtaaagag
    29701 tctcgacgcc ttcattttgc aatgtcttcg caaagttgtc atgttcttct tgagcaatcg
    29761 gaagatatgg aatatcatcg aacaacagac gatccataat atctggtgtc aaattttcca
    29821 cttcttgtcc aggccgtttc agtaaaactg tctttaattt ccctatttca gagaaaacgt
    29881 gaataggttt atccatgttg tgttgcctcc ttctttttga ttacatgtat aggatatcct
    29941 ccttttgtaa tcactttcat aattttgtct cattcaaaat gagacattcc tcacattaat
    30001 attcgataat taaataatta aacgtttttc tatttttaag cgtaatttat tcatttttta
    30061 ttctgtatac actttcaaaa aaatatttat tcattgaaaa aatttttttg aataaattaa
    30121 aaaaataaat tatattatcg ttgttagcgt ttactatatg tattattgtt gttttttata
    30181 cacaaatcat tcgcttcaaa acaaattatt caataccatt gtatattttt tacataataa
    30241 caaattatat ttgtaaagta ttaaaacttg tttctaatgt tggtatgtta aaactttaca
    30301 aattctttaa aaaaagtgac aataaatata gtgaacaata aggagaggac tttttaatgc
    30361 gtgttaataa aatcgatttt cacttttcaa aactcagata tcaacctgat tttgaacatt
    30421 tctcggatga agagttccaa cagatcaagg aacatactgt tcttcgttct tataaaaaag
    30481 gacagatcct tttcgacgat ggtgatccca gacaacggtt gtatatcttg accaaaggac
    30541 tcgttcgttt agaacgttat gatgaaagtg caacttatta ctactatgac tatgtgaata
    30601 caaataacct ttttcctatg tcaggaatgt ttggagaaga gacctacact tatacagctc
    30661 aagcgatgac tgatattgaa acattctacc ttcctgtttc ctactatgaa aaattagcac
    30721 gaaaaaatcc cgaacagttg atctatatga tacaaaaaat ttctaaagta gttgaaatac
    30781 atgaattgcg tatccaaatc ggattgacct ctagcgcctt tgaccgggta aaacaaaatt
    30841 tattcatttt gaaagaagaa ttgggcgtac caacaaaaga tggtcatatc accattcctt
    30901 atccgatcac cttaaaagaa ttagcagtga atagcggcac gacacgtgaa actgctggac
    30961 aagtaatcaa acaactacgt gattccgggc tgttagatta tgacaaaaag cgttttactt
    31021 tctgtaagac agctactact ccagctatga gagaataacg cgaacaaaaa taagcagtga
    31081 ccctgataaa tatcagggtc actgcttatt ttcctcccta aaacttctga aagatccggc
    31141 agttttagat cactggacaa gactcaaaga ttttctatgt gtgtttcagt tatgtaatat
    31201 tcactgtttg caaaaaatac tgttagatta actagatgaa gcgtcttgtc ctcatccgat
    31261 ctagattatt cgatattcct cgacaataaa cgattactca gtgagggcaa tcagaggaac
    31321 ggataatgat aaataagctg taaaaaatag caaaataaca ataatgatta aaagtatgta
    31381 aaaaataggg ctttgacaaa aacgtgtcac agccctattt cgattaaacg gtgtgtacct
    31441 gtcaactctt cggtcacaag tcataatgtt cataaacatg aggagctgtt ttttgaaatt
    31501 gttccttgtg aatcagagtt aaacgacagg cttacgaact cttgattaaa cggcgttcaa
    31561 aagcttgcat acgcggtaat aagaacagcc aggtcaaaaa catgagaagc cgtttttcct
    31621 gggctgttct tattacttga tgcagggcag ctttttcaca acctctttat tcagataaaa
    31681 ccaagcttgg atcagcattc aactgatagc tagcaaaatt tcttttttgc atttccacat
    31741 gtgctgctgc tccaatcatt gcagcattat ctccacaaag tcgaagaggg ggaatcacta
    31801 gttctacctc agggagttta gctgccaaag catcctgcaa tccttcacgc aacccttgat
    31861 tggccgctac acctccagct ataatcagtt gcttgactgg ataattttga caagctcgaa
    31921 gtgttttagt aatcaataca tcgatcacac ttgcttgaaa gctagctgct aaatcatttt
    31981 tgtctagatc ttctccacgc tgttgtgcat tatgcaccaa attgataaat gcacttttta
    32041 atccgctaaa actgaaatca taattatctt catggatcat cgctcgcgga aaatggtaat
    32101 tatcttttcc ctgatgagct agctgatcga tttcttttcc gcttgggtaa gaaagaccta
    32161 atactcttcc aactttgtca taagcttctc ctgctgcgtc atctcttgtc tccccaatga
    32221 tttcatatga tccatcttct tgcatataga ctaattctgt atgtcctccg ctaacaagaa
    32281 gtgccatcaa tggaaactgg aatggtttaa ccagacgggc tgcatagata tgccctgcca
    32341 tatggtttac aggaataagc ggcaattggt gtgcccaagc aaaagcctta gctgcagaaa
    32401 taccaatcag caacgagccg acaagtcctg gtccataagt gacagcgact gccgataaat
    32461 cttctgccga cacaccagct tctaccagtg catcttccaa gcataaggtg atttgttcta
    32521 cgtgatggcg gctagctact tcaggtacta cgccaccaaa acgtttatga ctgtttattt
    32581 gagaagcaac gatgttagat aagatctctg ttccatttct aacgaccgct acactcgttt
    32641 catcacaact tgattcaatc gccagaatca attcttcatt catttcatcg tctccgtttt
    32701 taactttctg ctcataatga tcgcatcttc cgtcggattg cgataatatg atttccgttt
    32761 acctaatata cgaaactttt ctgattcata aagttttctt gctgcttcat tagatagacg
    32821 tacttctaaa aaaacatgca gcgaatcttt tatttgttcc gtaatcagta attgtaacaa
    32881 atgccgtgca tgcccttttc cttgttctga aactgcaaca gcaatatttg tgatctcgac
    32941 ttcatctatt actttcgagt atccaataaa gccacagatc tggttatctt cagctaaaag
    33001 cagataatca gagtgaggct gttggatgtc tgccaaaaac tgcattttcg tccaaggtga
    33061 accatgtgga taagcatttt cgctaatcat ccatacgcat tctgccaagt acgcttcatc
    33121 aaaatctttt tttctgcaaa tcaactaatc tcactcattt tctaaaagtt ttatcatatc
    33181 caacgcatct tcttttgttt cagtgtaata tctttttttg atcgttgttg cttgaaaccc
    33241 caatttccga taaagtcttt gtgcatcttg attactcata cgcacttcta atgacatcgt
    33301 ctcacagcga ttcattatag caaagttctc gatttcgtca ataagcagcg aaccgattcg
    33361 tttacgctga tatgccggtc gaacggcaat attcgtgata tggcaatcta aaccgaacgc
    33421 tcttgaaccg ataaaaccaa tcattcttcc attatcaaag atacctagat atagatgagg
    33481 aagcggtgac ttcaattctg atataaaggc actttttgtc catggcaatt cgccattata
    33541 gacttctcgt tcgacatcca gcagctcttt gatatcttct gtagtcaatt ctcttagtac
    33601 gtaacgacga tcgatttgtt cgactgtttt ttctgtataa atcattttat cttgaaaaaa
    33661 gcttctggca tacgctctaa attttttcaa cataactttc gtctccaggt gtgtgcgtct
    33721 ccaaccattt ttcttctgct tctactcgtt ttaaatagcg aggaagaaaa gcttgtttct
    33781 ctgcaactgg ttcaactaaa gcacctaatt gagccacagt tacaccactt ggaatatccc
    33841 atgctggaac tgtattaatc atcgcactag gcaatatttc ctttatttca gagaagaatt
    33901 tgtgacaatc actcccgacg aaataaatag cttcattcag cttttgtagt tgtgtgaaca
    33961 aatcagaagc agaaatatgt acatcttcaa gtacagtttc taatctattt tctttccagc
    34021 ggtatgcccc agcgtataca ttttttcttc gagcatcaaa catgggcaca ataatattat
    34081 ccacaccgat gcaattagcc gcgatggttt tcagactaga tactcctact agctctttat
    34141 ctaatgtata agcaatcgtt tttgctgtcg ttacacctat acgaagccct gtataagaac
    34201 cgggaccatc agaaaccgcg attcggtcaa tgtcttttgg acttatttga agatctgcaa
    34261 acaattggtc gattgcaggc atcagtgtta cactgtggtt gcgtttgata tttgtttgta
    34321 tttgtccaag aatttgttcg tcttctacca caccgatcgc caaagtttgg tttgcagtat
    34381 ctattcctaa tgtaatcata tatttgatcc tttctgctat gacattctcg ccttccattg
    34441 tagcatactt ttttattctg aggatgaaaa taccaaaggc aaaactagta caataataca
    34501 tgattatctg ctggcgggca aattttgccc cttcctgaaa cacaaaaaag ctgcggtatc
    34561 actccatttt cccacagctt ttccatcttt tatttcgttg attctcgaat aatcaactct
    34621 gtttccacaa taatctttct tgaaaccggt gctttggaat tacttaattg aagaatcgtc
    34681 tccactgcta gctctcccat ccattcggta taaactttta cagtagaaag cgagggcgtt
    34741 acatatttcg ctacactgac atcattgaag cccatcacag aaatatcttc tggtaccact
    34801 aaaccttttt cttgaatcgc tttcagtgcg ccaatcgcta atgcatcatt agctgcaaaa
    34861 agcgcatcag gaacatgcgg attcgttttt aaatattgct tcactgcttg atatcctgac
    34921 tcgacagaaa aatctgcttc gataattgga ccttcgtcgt agcctttttc tgccaaaact
    34981 tgttgaaatg ccataattct gggatctttt agccgctgat ggtttttctt cgtatattct
    35041 gttccagcaa gcatagcgat atgttgcgct ttatgggaga caaagtgttc aatgactttt
    35101 tgaacacttg acttaaagtc gacaactaga gagtcgattc cttgagaagt gccgtcagaa
    35161 tctaccaaaa gcaaggcatt ttgggatcct ttcatttcta ataactgagc ttcgtcgaat
    35221 tttcctagtg cgatcgttcc atctgccgga agatcactaa tggaatccca cgtttctttc
    35281 aataaagtaa cgtttgcttc ttctgccttt ttttcgattc ctaggcgaat agataaataa
    35341 taaagatctt caagctcttc cgtatcgtcg taccactgga tcaggcgaag cgtttgctta
    35401 gtatttgctg catttttacg atgtttcgta taatttaagc gttctgctgc ttcaaaaatt
    35461 ttttgctttg tggctaagcc aacggaaaga tcaggatcat agttgagaac tcttgaaaca
    35521 gtagcaggag aaactcctgc caactgcgca atgtctttaa ttgttgccat ttgtctctcc
    35581 tcctttttta cgtttataaa atcgcagtaa atcgttcaaa cgctgcctgt cctttttcat
    35641 ctcgcttgaa tactccagcg tcttccagta cacgtgcaaa aacctgacct acagattttt
    35701 gtacgacatc ggtgaccgta tctttcgtca aatcaggatg ttcttttttt aattgttctg
    35761 cccacggacg atgatattca gccatctggt tttcttctcc taataagaaa tgctctactt
    35821 ctactagttc tggtttcaaa cgaggtggta aaacagcaag ccccattact tcgatcaacc
    35881 caatgttctc ctttttgata tgttggacat ctttatgtgg atgaaaaatc ccatcaggat
    35941 gttcttctga aacattgttg tctcgaagga caaggtccaa ctcaaagtaa ttgtcccttc
    36001 ttcgtgcaat tggcgtaatc gtatggtgtg gtgtaccatc tgctgaaaaa gctctgatag
    36061 atactgtttc atccgaatat gctttccatt tttccaatac tgagttagct gcttcaataa
    36121 gcaagttttt ctctgttgat tgcaaacgga tcacagacat cggccatttc acgactcctg
    36181 cgatgacttg cggataatct tctagtttga taagtttttc tatcggtgct tttgccatag
    36241 gaaattcatg acgtcctgcc tgataatgat catgagaaag aatcgatcct ccaacaattg
    36301 gtaagtcagc attcgaacca acaaagtaat gaggcaagac ttcagtaatc cgaagcagtc
    36361 tagcaaatgt ttcctttgtg attttcatcg ggcggtgttg ttctgataaa atgatcgaat
    36421 gttcattgta ataagcataa ggggaatatt ggaatcccca gctttcaccg tctagattca
    36481 ttcgaataat ccggtgattg gtgcgggctg gatagttcaa gcgacctcta tatccttcgt
    36541 tttccatgca aagcatgcag gtaggatagt ctacttttgc cgcctcgcgt tctgctgcga
    36601 tttgttttgg atctttttct ggcttagata aattgattgt gatttccagt tcaccatact
    36661 ccgactctgc cggaaatttg atgttttttg cgatggctct tgttttgatg tagtcatttt
    36721 tcttacttaa attaaagaaa tactcagttg cttcctctgg gcttttcgaa tagtgctgtg
    36781 caaagaatgc attgacgact gaaggtggcg gtgtgagaaa atccattaat tgcgcttcaa
    36841 aaatctcttg ttctgctggc aattctgaaa gaacaccatt ttctcttgcc ttagcgacaa
    36901 gctgatccaa taagtctaca gattcttcct taactggtct tacttcaatg ctttctagag
    36961 catcttctcc taccatccct aaaagacgat tctgtaaata taagcggtcc atttccatcc
    37021 atccgccagc ttcgatcgca agtgtggcaa aatcacaaat cgtttgactg attgacatat
    37081 ctcattcccc tattcttcat aaccatttgg atggctgaca tgccaatccc atgctgtttt
    37141 gataatcgct ttgatatctg tgtattcagg tttccagccc agaatctctc tcgctttttc
    37201 acttgaagcg actaatcggc taggatctcc agctcttctt ggtgctattt ctgctggaat
    37261 ttcttttcct gtcacttctc tagctgcttc tagcatttcc ttgactgagt atcctttgct
    37321 gctgcctaaa ttgaagaagt tgctttcatt tccttctttc aagtattcca aagctaaaat
    37381 atgtgcagca atcaaatctt ctacttgaac ataatctctg atacatgttc catctggtgt
    37441 atcataatcg tctccataaa cagccaaggc ttttctttga ccaagagcta cttgtaaaat
    37501 gattgggaca agatgcgttt ctggtgtatg atcttctccg atagatgcat ctgcttttgc
    37561 tccggctaca ttgaagtagc gcaaagcgac atagcgcatg ccatatgctt ggtcacacca
    37621 cttcatcatt ttttccatca tcaatttact ttcaccatac ggatttttag gattagctgg
    37681 tgtatcttct gtgattggag actctttcgg ctctccataa gttgctgcag tagaagagaa
    37741 tacgatttta ttcacgttga actcgtgcat gacttcaagt aagatttgca taccgtatac
    37801 gttgttgttg aaatacatca atggtttttc gacagattct cctactaaag agcttgcagc
    37861 aaaatggatt actccttcaa tcggttcctt ttcaaatacg gaacgtagaa attctttatc
    37921 ccggatgtct ccttcataaa aatgagcatc tggatgtact gcttgtttgt gacctgtgag
    37981 caaattatct accacagcta cttgataccc cttttgaact agctggtcta cagcgtgcga
    38041 accgatataa ccggctccgc ctagtactaa aattgtcata aaaaacactc ctttgattag
    38101 taaaattgtg tttgttgatt ctatataatt taaaaaacga agtttacttt tatggtgaaa
    38161 acaaacaaag taaaatttcg taaattcata tggtaaattt ataataaaac atttagtaaa
    38221 cattttcaag gtttttttgc aaaggtttac aaacaaacgt aaaactagcc tttttttctc
    38281 ttttgttcca taatagatat aacaaataat aaatgaggtg gattcaatga aaaaatttgt
    38341 atctggaata ttagtaggaa gtctggcaac agccgctgcc gttgctggtt tggttgcttc
    38401 tgtgaaaaaa acagtgatcg atccaattga cgaaaaagaa gcaatgatcg aagaaaaccg
    38461 taaaaaagca atgcgtaaac gcgtttctcg ttaataatta tttaaaaata cgcatgaaga
    38521 ctttctaaaa aacagataag tcatcatgcg tatttttatt tgtcagtcaa tataagttgt
    38581 gctattttat ctgcctgtct cagattccat ggatctgtat aaggtctagc tactgctgca
    38641 gttagccaat ccacaccttc aacaggtatt ccatagcaat aaaagtcaga ctggatttcc
    38701 cctgaagcat caatcacgcg attcgtacct cgctcaacat ctatagcttc tgaatgataa
    38761 cttcctgtat tatctgaaaa tgaaaaaggg cgaacaagtt tgttttcctt caaatttttt
    38821 atgacaggat tacttgaacg agaaaagctt gtttgtggca atcgagcttc aatcaaatag
    38881 cgactgctga tttctttatc ttgtagagaa ataacatagc ggttgtgctt ttgctgaata
    38941 tcaaatggcg gttcgatcaa atgaaaaata cccgcatcta tcagtgctgc taattctttc
    39001 gtccgaatga ttggcggacc gatcgttaaa aagctattta gatgagtaaa ccatccccat
    39061 agtatttctt tgtattcctt agcagaaaaa acgtgccatt caatagcctg ccggattgga
    39121 tcacgccagt cttttaatgc atcaaatgtt gaagcaaatg ctcctgtgca attgcctttt
    39181 tccgcttctt ttatctgccc ttcaataaat attcggctag cttctgaaaa gggctcattc
    39241 tgataggcaa gaggagtttc taaatacgac caatcccatc tataagggat tagtgctgga
    39301 tgctttccga gacactcctc tgaagagagg gagagaaaat catgctcaaa atttttcttt
    39361 ggaatcggca agtgatattc ttcgatgatt ttcttgtaat aaaacaactc aacgtctttt
    39421 ttcagatagt caaaaaatgt ttcgccagtc aaaaatcccg actgatgcca ttgctccagg
    39481 ttttcttttg ttagtaaccg tggccatgcc attgctccgc cttgcttttg atttcttcct
    39541 cgagggtaat aagggagccc ccttcttgat ccactgtata caatcggttc cttgcctgat
    39601 ggatgataga ccagttttcc cttttcgttc tcgaagcgcc ctcctcttga tactgtaaac
    39661 aatccgacat aatcaaaaaa acttaagcct agacctctta aaaagacatt ttctttaggc
    39721 ggtatcttcg aaagatctac atctgcagga ttagaaggaa gctgatacag taaaacattt
    39781 ttctttgcgt agtctaccca cactctttct tcttctgtct catcattttc ccagtgaccg
    39841 cttgctaaaa caagctgatc gatagaatag ctttgctgat ctgtctgtaa aagataacca
    39901 tcttttcttt tgcttacttt ttttactaaa gaataaacaa actgaataga agctggaaat
    39961 tcttcttgca actttgagaa aaaccagcgt tgatagagtc cgtataaaca tcgagtagat
    40021 tgctgatctt tttccagacg attgatttct tctataatta gttgcttatt tttggttacc
    40081 gtctgttcga tataatctgt agcaggtcct ttactccatt gaaacaagtt gggtccctgt
    40141 gttaccaatc ctccactgga caatgtttca tctgtaaaaa gcgtcacttg ttgagaaaca
    40201 gaattcatta ataactccgg tggctgattc aaccgccaaa ctcgacctcc aggaccattg
    40261 ggatcgaaaa gaaaaagttc aagagaatgt ctgtcctgat tattatggag aatcctttct
    40321 gctacactta atcctctagg tccggcacca atgatcccta ttttcatttg catgcctcca
    40381 tttcgataaa ttttttcaat aaaacagcat ggttctgatg ttcatttttt gcaccataaa
    40441 caaaagtaat gactggatgt tctttcataa gttgactgag tttaaaaata gcttgcttct
    40501 tttcttcttc gaaaatcaat tcttgctggt atttctttgc aaatgaagca aatcgttctg
    40561 gtacatggtc aaaagttttg cgtgcttcat tactaggtgc aatttctttc aaccacagat
    40621 ctaactgcgc tttttctttt gaaattcctc gtggccagaa tctatccacg agtattctat
    40681 agccatcctc tttttcagca tcaaggtaaa cacgttttaa tttgatcata gttgtttcct
    40741 tctttctacc ttttcgctta gcttatatat gtagataata gcacaaaata aaaaaaatga
    40801 acggcacaac tatccattgc gccgttcatg tgatcttggt caaaatctaa tgattgattc
    40861 ggtttttaaa gctgtcatac aatcatctgt tttatacttt tttacttttg atttttccag
    40921 accatccgtc atatccaccc ttaagtaaat aaatctcttg ataacctgct ttacgtaatt
    40981 tatttgctgt acggatgctc aaacttttct tttgatcgta aatatagaca ggctggtctt
    41041 ttcgaataga tcctaatgaa tctttcaaaa cagtgtaagg gatgtttctt gcacctaaaa
    41101 tatgcccagc atcaaacaca tctttttcgc gaacatcgat tacttgtgct tttctcattc
    41161 cttctcgaaa ttcttcttct gtcaaagtcg ttgctgaacg tttggccatt actcgtagat
    41221 agacttccca aaggatgatt gcaagcacaa tcaatagcaa aatgatatta attacccata
    41281 aaaccatgta atgcctccgt ttttttaagc aaatttcaag gctaatgagg cagcaccaat
    41341 gacaccagct tcattaccaa gctctgctaa tttgattttt gttgattctc ttacttgcgg
    41401 gaaagtaaat tctttaaaat atttctctac acggctacgt aaaaattctc ctgctgccga
    41461 tactcctcca cctaacacga tacttgacgg atttaatgta ttccccaagt ttccgcaagc
    41521 taaacctaag tagaagcata cgcgatcaac aaccatcaat gcaaacggat cgtcttcttg
    41581 agccatttca aagatatctt tacttgttac ttcttctccg ttgtctagca ttgctttcag
    41641 ttttgaatcc cctgcgtatt cttctgccaa gaaacgacct aggcgtacca cacctgtagc
    41701 gctagataca gtttctaaac atccgcgttt accgcaagta cattcgaacc cttcaggatc
    41761 cacagtgata tgtccgattt ctcctccagc tccgctcacg ccgtgaatca aatttccgcc
    41821 agcaacgata cctccgccaa cacctgttcc tagagtaacg aatacaacgt ctggatcgtt
    41881 ttctccagca cctttccatc gttcacctaa agcagcaaca ttcgcgtcat tatcgatagc
    41941 gaatttgatt cctgttcctg cctcgatcag ttttttcaca aattgaactt ctgtccagtt
    42001 taagttatac gcaccaataa ccgttccagc ttcgctgtcc acgcttcctg gggtacccat
    42061 gccgattccg ataaagtctt cggctttcat attatataaa ttcaaacgat gattgattga
    42121 ttcaatgatt tcaggaacga tatgcttacc atcatccaaa atattggtat cgatgctcca
    42181 tttttgctga atctctcctt ctggtgttaa aattgcaaat tttgctgttg ttccacctaa
    42241 atcaatccca ataatcttct tgtccattac aaatttcctt tctttcggct ttcttcaatt
    42301 cggtgctctc tttttaatat gcgccacgct gtcatgtatg tatcatgatc aatcaaacgg
    42361 ctatcataca gattacgcaa ttcgatagtc attaattcaa tgtcatagat gcgtgcaccc
    42421 acatagataa agatgccaaa ttttttgaac agctgctgta catcatataa gctctccatc
    42481 tttaagcact tccttcatat tatacaagta aaccatattt ttttaaaccc agtaaaatac
    42541 atattacaaa aagaaataca aaaactagtg tagaaagaat cctttggtgt atcgaatagc
    42601 ttgtctgttg tttcggtaga cccaaaacat tccctaacac taatccgcca attagcccac
    42661 cgacatgtcc ccaaacatct acagaggtat ccagaagacc aaaaacaaat gtcaacacaa
    42721 taaataaaag aaaatgtctg actagctgct ggatcgctgg gttatgttta aaatgaaacc
    42781 ctaagataaa caacgcaccg aacaaaccga atatcgaagt acttgcacca ccagacagaa
    42841 cattcgcttc gttaaaagca aagcttgctg tatttcccat tatcccgctg aacatataaa
    42901 tcaagaaaaa acgccaatgg ccatagattg cctcgatttg ctgccccata aaatacagta
    42961 tcagtgagtt cattacgaaa tgcatcagtc caaaatggat gaagattggt gtcactaaac
    43021 gccaccattc attgaagtga acaagataag gaccatacat tccggcataa taagggatct
    43081 caagtcgcgg aaataattcc atcatgagga agaccgctgt ctgtatccct aaaaaagcat
    43141 aggtccataa cggtcgtctt aaccatgcac gcaattttat ttgctgttga taattcatga
    43201 aaacctccca tttcatttta gtcaataaac aattgttgga tcttctgatc aaagctctcc
    43261 ggttgccatt gttcattcaa ttgttcacga aaaacaaggc tacatgtttt tttatgaaaa
    43321 ttatttaaat accggtcgta ataaccaccg ccaaaaccga ttcgataacc ggctctattg
    43381 tagataatac ctggtacaat gaggagatcg atcatctccg gcaaatagag cttctctgat
    43441 tgtggctcaa gaacaccaaa actcgaacgt acaagaacgg actgttcatc catttcataa
    43501 aacgccatct gacgtttcgg caaagtttta ggtacaacta ttttcttttg ttctttttct
    43561 gctcgttgga taaccggctg tgtatccagt tcaaattcat tcgataaagt cgtccctatc
    43621 acttttgctg acttccagta ctcgctggcg aatagctgtt tatagattcg ctgttctttt
    43681 tcctttttct tgccactttt ggccagattt ttcagctttt cgattccttt ccggcgtaat
    43741 cttactttca attggtccaa aaactcaccc ttccttctct cataaaatgg tataggaaaa
    43801 aaagaaaaat agcaatcgaa ctttcaaata aatgcataaa tagaataaaa agaagaccta
    43861 gaaatgattg gccttccttt tttaatgaat ttcaactgtt cagcgcgtgt ttttgtctga
    43921 taaaaagtgc atacagaaaa tatggcgcac caaaaagggc aatcaaaatt cctgtaggta
    43981 cttccccact tggtagaatc actctagcaa ccatatctgc actaagcaga aaaatggaac
    44041 cgaacaaacc gctcagaaca aaggtccagt tattttcttt acgtacgact agcttcgcag
    44101 catgaggagc tagtagtcct acaaaagata aactacctgt caccgctaca ctaccgcttg
    44161 ccaaagcaac agctaacaac aaaaggattt tttgactttt agccacgtta aggcctaatc
    44221 cttgcgcgcg ttcttgacca aatgatagca atacaatcct ctgtgcataa agtcctccta
    44281 gcggaattaa gataaccgcc catggaagca atgcccaaac ataaggccag ctcgcacccc
    44341 agattgatcc cgctaaccat gcattcacaa atccataatt ttccttagat aattggatcg
    44401 tgcatagcaa tgttaatgca gaaaggccgg cattaacggc aataccggac aataagattc
    44461 gattcatacc caaaaagcca tttcgatcat aggccgcaag atagacacag caagcagcta
    44521 aaacaccacc tagaaaggct acaactagca atagaaacgg cagcgaatag tgcgaaaaga
    44581 aacctaaata aagcatcact aaaaatcctg ctccggcatt aatgcccaat atactagaat
    44641 ctgccaattc atttcttgtt actccttgca agatataacc agaaacgcca agacaagctc
    44701 ctgctaataa actgatcagt aatcgaggaa ctcgaaattc tctaacaatc agcgccaaag
    44761 aagatgattc tttccctatg aacgtggcaa aaagctgatc caggtaaata aaaggcgtac
    44821 caatcattaa actacctata gacaggatga caagtacaaa aagcaagaaa tagaacgtcc
    44881 aatatatttt tttcaccgtt gttccctcct tacttgtatc agtaaaaacg gaacgccaat
    44941 caatgcaatg actaatccaa aaggtgtttc aaaaggggga ttgatcatcc tcgctgtaaa
    45001 atccgccaac ataaccaatc caccgccaac taaaaaagag acaggtagaa cataacgata
    45061 gtccgttcca accattccgc gaacaactgg cggaaccaac agcccaataa atgaaacagg
    45121 tccgactaac gaaacggcaa tggctgctaa cactgcaact agacagaaaa caatcaaccg
    45181 cgttcgttta ggatgacttc caagagctaa tgcatgtgtt tcactcaaat gaatcaaaga
    45241 tattgctttt cctaatgaaa aagaaaccaa aacagcaagt atatataaag gaaacaatac
    45301 tgctaattgt ttccatgtga tattggcagc tccgcctaca aaccaaaaag caagatcctg
    45361 ctgcagatta aagaattggg taagtgcttg gctgatagca gtaaaaaaag aactaatagc
    45421 tacgccagct aaaatcagct gtaaaggatt catgcccatt ttcgaaaact gcaaaaaacc
    45481 aaatacgagc aaagttacag caaaagaacc tgccaatgac attagaaaca cagaaaaatc
    45541 agaagcttta ggccaaaaag caaaactaag ggccattgcc aacgaagcac ccgcgttgat
    45601 tcctagtaag cctgaatctg ctaaaggatt tcttgtcact ccttgcatca atgcaccgct
    45661 caatgcaaaa caactcccta caagaaatgc tcccgccaca cgaggcaaac gaatatttcg
    45721 tatgatttgg tgactttgtt ttgatctatc aaaatcaaac aacgcctgcc aaaaatctgc
    45781 tttttccaca gtcgctgcgc catttgaaag agcaacaaaa aaaataatca aaagaacaaa
    45841 acagaccaaa agcaggagtc tatttttctt catagtcctc ataattgatc ctcctgctct
    45901 tttggcaaca aatcataggt tagaaaaact ggtttatttg ttcttggaag cgtgacaatc
    45961 gttgcatcaa tctcaaatat ttttttcata cactcttttg tgatcacttc ttcaggtgta
    46021 ccttctgtga tcaacttacc gtttttcatt gctaataaat aatctgaaaa acgtgaagca
    46081 tgattaatgt catgaatcga catcaagatc gttgtttgtt tcatttgatt gatttcagtc
    46141 aataactgta ggatctctaa ttggtgtgcc ggatctaaaa atgttgtcgg ttcatccaag
    46201 atcaagatat ctgtttcctg agcaagcgcc atagcgatcc agacacgctg ggtttgtcca
    46261 ccagacagcg ttgcgatatc ccgcatacga aatccagcta gacctgtagc atccaacgcc
    46321 cactcaattg cttcatgatc ttgcgtgtcc atgccactga acagtttttg ataagggtat
    46381 cgtccgtaag atactacttc ttctactgtc atacctgtag ggtgttcact agtttgtgct
    46441 aataatgcaa ttttttttgc aagttctttt gaactgtatg tagagatatc agagttattg
    46501 acaatgatct ttcctgattt cacaggtagt atacgggtaa aacttttcaa taaagtagat
    46561 tttccacttc catttggccc aatcaaacta gtgattttcc cttcaggaat cgtaacagac
    46621 atgttttcaa tgattttttt gttttcgtag ccggctgcaa tgtcagctgc tcttaatctc
    46681 gtcatttcac ccatcctttc gctgaaaatc attctcaatt atgacgctgt ttcaacattt
    46741 cgtcaagcgc tactttcata tctatagcca aatgaagcgg ttgacagcgt tcgaaatatc
    46801 aggaataata accaatgaga aagattctca attatgttag gaggaaagaa atgaaattaa
    46861 aaacaaaagt attcacatta tctagcatat tgctgctggc tggagtactg agcgcttgct
    46921 ccccctcttc agataaagaa acagctacag ctgccaattc gacgacttca tccaatagta
    46981 ctcatacagt cacagataca cttggacata aagtagagat tccaaacgcg cccaaacgga
    47041 tcatcggcag ttacttagaa gactatctga ttgcactagg ggaaaaacct atcgcccagt
    47101 ggactgttgg cagtggttcc attcaagatt atctgcaaga tgatttaaag gatgtcccaa
    47161 cgatttctta tgaccttcct tatgagaaag tgttaagctt tgagcctgat ttgctgttga
    47221 tttcttcttc cgctactgtc gaaggcggga aatacgaaca atatagcaaa atcgcgccaa
    47281 cttatgttgt aaaaaacgga acagatgtca catgggaaga acaactaaaa gatgtcggca
    47341 aagctttggc aaaagaaaaa gaggcagaaa aaatcatttc cgattatcaa aaatccatca
    47401 agaaaactcg agaagaacta gcagataaaa tcgagaacaa gacagctgca gtgttgtggg
    47461 tgaccaacaa ctcagccttt atggtcagca aaaatcggtc aagtggaaga atcgtatacg
    47521 acgatctgga atttggtgtt cctgatctag tggaagaggt ctccaaaaaa gccacttctg
    47581 actggtctgc tgtttcctct gaaaagctag ctgaattaga tgctgactac atcatccttg
    47641 tgaacagtga caaagatgct gccatgttca atgaaccaag ctggaagaat ctaaaagcag
    47701 tgacagacaa tcatgtactg caattcggac ctgaatctag ttggctatat aacggaccta
    47761 ttgccagtca ggaaatggtc aatgatatca aagaaaaact aaattgattt taactaaaaa
    47821 aagcatcttc acgattagtc gtgagatgct ttttttctta ttaacaaact agacgcatag
    47881 attttattct tcttttgaag caaccctatt ttttactctt tcccattttt gaaaacgatg
    47941 ggcatataga ttttcttgat ccgttatccc ctcatactcc tctataaggg cgaagtctga
    48001 aaaatcaata ttcccaatat acgtatcgcc ttcaaacgtg ctatcgatca atgttcgcca
    48061 gatccgacca gtgtaaggaa gaagttcttg aaaaatccga ctaccacccg aaacatagat
    48121 atcttctgag atcgtttgac tatacgacaa aagttcatcg atcgaatgca ttacttccgc
    48181 attttctttc gtgcgaaaat ttggttgcgt tgtcaacacg atgatatggc gataaggaag
    48241 tgaaagatcc cccattcctt cataggtctt tcttcccatc actaaaattc gatccattgt
    48301 atgttcgcga aagaaacgca tatcatttgg caatcgccat ggtaacaaac catttttgcc
    48361 gatcagacca tttttatctt gtgcccacat ggaaataaac atattatccg ctccttatga
    48421 ttttagatgt tttgagataa aaaaagtctc aattctttga ccagcaagga attgagaact
    48481 ttaaaaacat tattttgttt cacggtgcaa agtaactttg cgttcgcgtg ggcaatattt
    48541 ttgtttttcc aaacgatcag gattgttacg tttgtttttg cttgttagat agttacgttc
    48601 tttacaagaa gtacactcta aagtgatgtt tacgcgcatg tttttccctc ccatttttac
    48661 aagaatcctc taagatgact ctcagacttg attatcttac catgattttt tctagattgc
    48721 tagtgttttt cacgattttg ttaagtaaaa ctacttgacg ataaatacaa cggttttact
    48781 tctcaaacaa aatctttttc tttttgtata aataccctta cacttgttta tatagattat
    48841 gttttttaat aaagggggat actaatatgc catggaacat gaaggacttt cctgcatcaa
    48901 tgaaaaactt agataaattg acaagaaaaa aagcaatcga catcgcaaat gcattattag
    48961 atgaagggta ccctgataac cgtgcgatcc caattgccat tgatcaagca aaaaaatggt
    49021 atgaagatgc tagtgaatca gaaaaacgaa ctttcgaaaa agaaaaaaat ccaagcaaga
    49081 cggatgaaca cgatacgaat cctcgtgctg gaaaactgct tgattcagat gtgatcgtag
    49141 aatatgagga agaacaatgg atcgtgaaat ctaaaggggc aaaaaaggca agcaaccatt
    49201 ttgatacaaa aaaagaagca atcgaaaaag gaaagcaagt agcacaaaac aaagaatcaa
    49261 ctttgttcat ttataaaaaa gatgggacaa aagaaaaaga aatcgattat tgaacatatg
    49321 taaaggggtt gtgacgaaaa tcgtgtcaca acccccttat gttcgaaaca atggtgttcc
    49381 tctgccaact ccgaaccata agtcataata tctataaaac gggaagagct gttttttgaa
    49441 attgtttctt atcactcagt gttaaacggt aggagaaaac ctctttttta ttgatatttg
    49501 attttcatca aacagtcaca tagtcgattg cttctgcttg cggaatcgtt tcatctacaa
    49561 agtagacttt ataccatgtc aagaaactga agattgtcca gatttttctt tgctcttctt
    49621 tacgtccttc gtgatggtca tctagcaact tcatgatttt ttcttgatca aaaaattctt
    49681 ttgcaaaatc tgcttcgaat aatgctttga cttgttcgta gccgtgttct tctttcaacc
    49741 aagctttgat tggcacaggg aatcctaatt tcacacgatt cgaccattct tccggaagat
    49801 gtttgttcgc agcttgtctg aaaatatctt ttgtgttgtt ttgattcaat aaaaacttac
    49861 ttggtatttg ttgagccaat ttcatgactt cgatatccaa taaaggtact cggacttcca
    49921 aagaacttgc catagaaagt ttatctgcct ttaacaagat atcttttggc atccattgat
    49981 gaagatcgac atattgcatc ttattgactt catctttgat tccttctgtt ttctcgtaat
    50041 gaacagtcat gatttcatcc acagatggtg ctgtttgata ttttggtgtt aacacttctg
    50101 atgcttctga ttcttcgaac actcgagcat gaccgataaa atattctttt gcaggagcaa
    50161 gtgattcata taaatggatc cgtccatgga agtttttcat ttttccgatt ttacgtccta
    50221 aattatagcg tgttcctttt ggtaattttt tcaatccttg agcaatcaca cggatgaatt
    50281 ttgaattcgt atggaatcca tacgtttggt atcccgcaaa cagttcatcc gccccttctc
    50341 cagattggac tacccgcaca ctttgtgaag caagatttgc taaaaagtac aaaggtacgc
    50401 aagaaggatt tgaatcaggt tcatctaagt gatactggat caaagggaat gctttgaacg
    50461 acatgtctcc gtcgatcact gctgctgtat tatctaagtc caatagttcg gttagttttc
    50521 tggcttcaat cgcttcatta taggttttat catcaaaccc gattgagaaa gaatgatctg
    50581 gtttcaatac agaggttaca taactggaat caaccccgct ggataagaaa gaaccaactt
    50641 ctacatcact gaccgtatgt gcttcaatag aagcttgaac ggtttcgtcg attttttcga
    50701 tccattcttg tcgggaatgc gtttcttttg tttcaaaatc tgcatcccaa tattgctgaa
    50761 tgtctatttt tccatcttta tacgtataat aatggccttc aggcaaacga tagacatctt
    50821 tgaagaatgt ttcgccgttt aatggagaat attggaaagt catataaggt ttcaacgctt
    50881 ctttgttcaa ttctttgtta aaatcaggat gaggcagaaa acttttgatt tctgaaccaa
    50941 acataaatgt tccgttcatt tctgcataat aatatggttt gatcccaaag tggtctcttg
    51001 caccgaataa ctcattcttt tcattatccc aaatagcaaa agcaaacatt ccgcggatct
    51061 tttgcaataa ttctgttccc cattcttcgt aaccatgcaa aaggacttct gtatctgcat
    51121 gtgtttgaaa aacgtggcca gctgcaatca attcttctct caaaggctgg taattataga
    51181 tttcgccatt aaaaataatg atctttgtcc gatcttcatt gtaaataggc tgagtaccgc
    51241 cctctaagtc aataatactt aatcttctga atcctaaagc aacatgttta tcgatatatt
    51301 ctcctgaact attaggtcca cggtgaacga ttcgatccat cattgtatta ataattgttt
    51361 ttttgttgtc cttgtcgtta acaaaaccta caataccgca catttaactt tcacatccta
    51421 atataaaatt actgtttatt tcattcatat gcatcttatc atagaataaa tagcggacga
    51481 atattttctc tcttacaatt tcgtcacgtg aaaacaaaag atgaaagttt ctgtttttac
    51541 agaaaataaa gtcccaatat ctaatttacc atgttttctt ttttgaggct accttattct
    51601 cttcgtgtta aaaaaatatt agtggatgct atttccaaaa aaaccagcaa aaaaagacac
    51661 gacctaaaga tcgtg
//
LOCUS       DAFEML010000015        50737 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFEML010000015
VERSION     DAFEML010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.015"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(148..2301)
                     /locus_tag="LP468_000992"
     CDS             complement(148..2301)
                     /locus_tag="LP468_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL2080545.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2696..3544)
                     /locus_tag="LP468_000993"
     CDS             complement(2696..3544)
                     /locus_tag="LP468_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2080546.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="LP468_000994"
     CDS             complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="LP468_000994"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL2080547.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(6045..6224)
                     /locus_tag="LP468_000995"
     CDS             complement(6045..6224)
                     /locus_tag="LP468_000995"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL2080548.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="LP468_000996"
     CDS             complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="LP468_000996"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2080549.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8372..10651
                     /locus_tag="LP468_000997"
     CDS             8372..10651
                     /locus_tag="LP468_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2080550.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10744..11391)
                     /locus_tag="LP468_000998"
     CDS             complement(10744..11391)
                     /locus_tag="LP468_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080551.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11570..12289)
                     /locus_tag="LP468_000999"
     CDS             complement(11570..12289)
                     /locus_tag="LP468_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080552.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12420..13571)
                     /locus_tag="LP468_001000"
     CDS             complement(12420..13571)
                     /locus_tag="LP468_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL2080553.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13788..14528)
                     /locus_tag="LP468_001001"
     CDS             complement(13788..14528)
                     /locus_tag="LP468_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2080554.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14532..14855)
                     /gene="rsfS"
                     /locus_tag="LP468_001002"
     CDS             complement(14532..14855)
                     /gene="rsfS"
                     /locus_tag="LP468_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL2080555.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="LP468_001003"
     CDS             complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="LP468_001003"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL2080556.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15489..16139)
                     /locus_tag="LP468_001004"
     CDS             complement(15489..16139)
                     /locus_tag="LP468_001004"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL2080557.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="LP468_001005"
     CDS             complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="LP468_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL2080558.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="LP468_001006"
     CDS             complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="LP468_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL2080559.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKENKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17582..18109)
                     /locus_tag="LP468_001007"
     CDS             complement(17582..18109)
                     /locus_tag="LP468_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL2080560.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18289..19074)
                     /locus_tag="LP468_001008"
     CDS             complement(18289..19074)
                     /locus_tag="LP468_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL2080561.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19067..19936)
                     /locus_tag="LP468_001009"
     CDS             complement(19067..19936)
                     /locus_tag="LP468_001009"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL2080562.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19937..21316)
                     /locus_tag="LP468_001010"
     CDS             complement(19937..21316)
                     /locus_tag="LP468_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL2080563.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21324..21743)
                     /gene="fabZ"
                     /locus_tag="LP468_001011"
     CDS             complement(21324..21743)
                     /gene="fabZ"
                     /locus_tag="LP468_001011"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2080564.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21768..22244)
                     /gene="accB"
                     /locus_tag="LP468_001012"
     CDS             complement(21768..22244)
                     /gene="accB"
                     /locus_tag="LP468_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL2080565.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22247..23482)
                     /gene="fabF"
                     /locus_tag="LP468_001013"
     CDS             complement(22247..23482)
                     /gene="fabF"
                     /locus_tag="LP468_001013"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL2080566.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23501..24238)
                     /gene="fabG"
                     /locus_tag="LP468_001014"
     CDS             complement(23501..24238)
                     /gene="fabG"
                     /locus_tag="LP468_001014"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL2080567.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24250..25167)
                     /gene="fabD"
                     /locus_tag="LP468_001015"
     CDS             complement(24250..25167)
                     /gene="fabD"
                     /locus_tag="LP468_001015"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL2080568.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25274..25498)
                     /locus_tag="LP468_001016"
     CDS             complement(25274..25498)
                     /locus_tag="LP468_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2080569.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25551..26513)
                     /locus_tag="LP468_001017"
     CDS             complement(25551..26513)
                     /locus_tag="LP468_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL2080570.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26523..26963)
                     /locus_tag="LP468_001018"
     CDS             complement(26523..26963)
                     /locus_tag="LP468_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2080571.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27269..28234
                     /locus_tag="LP468_001019"
     CDS             27269..28234
                     /locus_tag="LP468_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2080572.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28291..28521)
                     /locus_tag="LP468_001020"
     CDS             complement(28291..28521)
                     /locus_tag="LP468_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL2080573.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28607..29494)
                     /locus_tag="LP468_001021"
     CDS             complement(28607..29494)
                     /locus_tag="LP468_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL2080574.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29583..30806)
                     /locus_tag="LP468_001022"
     CDS             complement(29583..30806)
                     /locus_tag="LP468_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2080575.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30823..31869)
                     /locus_tag="LP468_001023"
     CDS             complement(30823..31869)
                     /locus_tag="LP468_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2080576.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(32033..33760)
                     /gene="ptsP"
                     /locus_tag="LP468_001024"
     CDS             complement(32033..33760)
                     /gene="ptsP"
                     /locus_tag="LP468_001024"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL2080577.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33760..34026)
                     /locus_tag="LP468_001025"
     CDS             complement(33760..34026)
                     /locus_tag="LP468_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL2080578.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34505..36739
                     /locus_tag="LP468_001026"
     CDS             34505..36739
                     /locus_tag="LP468_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2080579.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36887..37207
                     /locus_tag="LP468_001027"
     CDS             36887..37207
                     /locus_tag="LP468_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2080580.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37412..37636)
                     /locus_tag="LP468_001028"
     CDS             complement(37412..37636)
                     /locus_tag="LP468_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBL2080581.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37834..39414)
                     /locus_tag="LP468_001029"
     CDS             complement(37834..39414)
                     /locus_tag="LP468_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL2080582.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39815..41191)
                     /locus_tag="LP468_001030"
     CDS             complement(39815..41191)
                     /locus_tag="LP468_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2080583.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41319..42437)
                     /locus_tag="LP468_001031"
     CDS             complement(41319..42437)
                     /locus_tag="LP468_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2080584.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42579..43013
                     /locus_tag="LP468_001032"
     CDS             42579..43013
                     /locus_tag="LP468_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080585.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(43091..43624)
                     /locus_tag="LP468_001033"
     CDS             complement(43091..43624)
                     /locus_tag="LP468_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL2080586.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43718..44896)
                     /gene="mutY"
                     /locus_tag="LP468_001034"
     CDS             complement(43718..44896)
                     /gene="mutY"
                     /locus_tag="LP468_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL2080587.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44889..45686)
                     /gene="recX"
                     /locus_tag="LP468_001035"
     CDS             complement(44889..45686)
                     /gene="recX"
                     /locus_tag="LP468_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL2080588.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45793..47175
                     /gene="rlmD"
                     /locus_tag="LP468_001036"
     CDS             45793..47175
                     /gene="rlmD"
                     /locus_tag="LP468_001036"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2080589.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47349..47927)
                     /locus_tag="LP468_001037"
     CDS             complement(47349..47927)
                     /locus_tag="LP468_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL2080590.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48249..48719
                     /locus_tag="LP468_001038"
     CDS             48249..48719
                     /locus_tag="LP468_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL2080591.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48827..50053)
                     /locus_tag="LP468_001039"
     CDS             complement(48827..50053)
                     /locus_tag="LP468_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2080592.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT        14438 a        10779 c         8732 g        16788 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa acaagaagta tttaatattt ttttcataaa atctttcatc
     2401 atttcctatc cttccgccta tttacattca tgcttcattg tacccaaaaa cttcttaata
     2461 aaaaagaaaa aatgggcgga gcaagaaatt ctttacctaa tttcaagata aaatcaactt
     2521 tttgtttcac agcaatcact taaagttaca tatccaacta tttttttcat taaaaaataa
     2581 acttattttt gaaaattatg ttttcttaag tcgtgaaaca ctttgatgga tcatttattt
     2641 gtggaaaact acgttttgtt attctaaaaa acttatataa aaaatagtaa ggtttttatt
     2701 tcgaatccat aaaatattct tggattgctt ctcgtgtttt tttcactttt tcgctaagct
     2761 tttcgttttt agccatatag aaataaaaaa tgatatcgat cgtagcaaat tgggccaaaa
     2821 gtgaattagt tgccgcactt cgattcgtga tttcttttgg tctagatgtt tgtacgagta
     2881 catcggctat cttgctaagc gggttatttc caaattgcgt caacgcaatg atttcgatat
     2941 tcatgctttt cgccagctcg gctaatgcga ctacatctgc acttctacct gagtttgaaa
     3001 caagccaaag cactttcttt ttctcattgc tgacaagttg cgggagcaag acgtggatat
     3061 ctttttcaaa aatgattggc ttaccgacac gagaccattt ttgcagaata tcttctacta
     3121 ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc tgccgattcc aaacactcta
     3181 cgactttttg gatcgtttct tcttctagaa tatctactgt ttcttttatc gctacttgtg
     3241 cattgttacc aagtttgttt ttgatagagt aaaaggactc atttgcttct atatcactaa
     3301 aaccttcatc gattccagtc tgtagttctg ttgaaatcgt gattttgaag tccgtcagac
     3361 tttgaaaacc gatttttttg gaaaaacgta caactgtcgg cgcactcaac ccggaagctt
     3421 ctgctaattc attagctgtc attgtaggga ccttctcaat attaccgata atgtagttgg
     3481 ccaacttttt ttctgctgaa gaataatctt ccatcatact ttcaatacga ctaattacgc
     3541 tcataagttc ctccaccctt ttaatgatag tctatgtaag tataccatat cagaccctta
     3601 ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc gcccaacaga atatcttatc
     3661 ccatcaatcc cacagattct attgagcatc tgtgtctttg aggaatacct gttatctatt
     3721 gttcggattg ctttctatct actacttttt tacaggaaat ttacctatta gttttctctg
     3781 ctgtaatttt tgacttctgc ttccatagca tcaataaaga tattcaaatc ttctacagct
     3841 gtttctttac ttccataacg acgtacgttc actgttgcat cttccaattc cttgtctcca
     3901 acaactaatt ggtaagggat cttttgtgtt tgagaggcac gtatcttata gcccattttt
     3961 tcattacgat catcaacttc tacacgcaac cccttcattt gcaaacgttc tttgatttca
     4021 taagcataat cgccatgtgc atcaacagaa acagggatga ttgttgcttg tataggtgcc
     4081 aaccatgttg gaaaagcgcc tttgtatact tctgttaaat aagcgacaaa acgttccatt
     4141 gtagaaacaa ttccgcggtg gataactact ggacgatgcg tattttcccc gtcttctcca
     4201 acatatgtca aatcaaagcg ctctggcaat aagaagtcta attgtatagt tgataatgtt
     4261 tcttctgtac caagagctgt tttgacttga acatctagtt ttggtccgta aaaggctgcc
     4321 tcgccttctg cttcaaagta atctagttct aattcatcca tagcggcttt cagcattgct
     4381 tgggcttttt cccacattgc gtcatcatca aaatatttat ctgtattgtt tggatcgcga
     4441 tagctcaagc ggaaacgata atctgtaata ttgaagtcag catatactgc caccatcaat
     4501 tcaagcgtac gtttaaattc atctttgatt tgatcaggac gaacaaatgt atgaccatca
     4561 ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag cacctgattt ttcatagcga
     4621 tgcatcattc ctaattcagc gatacgaatt ggtaattcac gataagaatg gatcgtgttt
     4681 ttgtagacca tcatgtgatg agggcagttc attgggcgaa gaacaagcat ttcgccatct
     4741 cccatatcca ttggcgggaa catgtcttct tgataatgat cccagtgtcc agatgttttg
     4801 tacaactcaa catctcccat tattggtgta tatacatgtt ggtaacctag actaacttct
     4861 ttgtctacga tataacgttc gatcgtgcgt cggattgttg ccccttttgg aagccagaat
     4921 ggcaaaccag aacctacttc tggggaaacc atgaacaagt caagttcttt tcctagttta
     4981 cgatggtctc tttcttttgc ttcttcacgg agacggatat attctttcaa agctttcttg
     5041 tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat tgtttgagtt tccacgccaa
     5101 taagcacctg ccactgataa taatttaaat acttgtatac ggccagtgga tggaacatgt
     5161 ggtccacgac acaaatcgat gaattcgcct tgttgataag cagtaatcac ttcttcttct
     5221 ggcaattcac taatcagttc tactttgtac ggatcacttg caaaaatttc taatgcttcc
     5281 tgttttgaaa gaacacggcg ttcgatcggc agattttctt tgacgatttt catcatttct
     5341 gcttcgattg ccggcaaatc ttctgcagtt acttggtttt gtccattatc tgtatcgtag
     5401 taaaaccctg aatcgatagc tggtccaacg ccaaagtgga tatttggata gaggcgacgc
     5461 atggcttggg ccatcaaatg agctgctgaa tgacggacta agccaagtgc atcttcatgg
     5521 tctggtgtga tgatctcaat acttgcatct tcctcgattg gacgagtcaa atcaacgagt
     5581 tttccgttca ctttaccagc taaagctttt tttgctaagc tttttgaaat gctttcagca
     5641 attgccaatg ttgttgttcc agactcaaat tctttgactg caccatctgg aaaagtaatt
     5701 tttatcataa tagtttcctc cttgaaatgt tttgattgat cagatcatca agctgaaaaa
     5761 caaaaaaatc ctagcatctc ttgaaaagag atactaggac gaaaagttcg tggttccacc
     5821 taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg gtccgaccgc ccttgcttca
     5881 acaagggttt cgaaagtggt catcctttgg ttttctcctg gaaaagtttc agcctagctt
     5941 ttcctctctt atcgaagact ctcaaattca gttggctttc tcatcaatca attatgtgtt
     6001 tatttaacca ctaataaata gaaaaatcaa gtgggaaact aaacttattt tttccattcc
     6061 ccatttacac cgtatgttcc ttttttcatc tcattgatga tgacatggat gtgttctttt
     6121 ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt tcatcatatt ttctaattgt
     6181 tccggactgc gaccttctac taattcgaca tgtacgaatg gcataatgct ctctcctctt
     6241 tctgatcgtt cttttttcaa ctcgattcta tcatactatg tttgtcttgg gtactgaatc
     6301 aggaaaaatg gctggatctt tttttgctct caaggcactc aaaatagaga ccgtatccac
     6361 gacttcttgc aaaacagctc cgaataatgc ggggattagt cccgtacttg caattaacat
     6421 caaaaaaata caaataaaga tgccaatcag tacagactgt ttcgctattc tcatcgtatc
     6481 tcttgaaatc actactgctt ttgctacacg caagagatca tctttcaaga tgaccgcatc
     6541 tgcactttca ctagcagctg tagaaccatg agcccccatt gcaataccga tatctgcagc
     6601 agcaagtgct ggtgcgtcat tcacgccgtc tcctaccatc gcaacaggtc tttgatcttt
     6661 agggatactt tctaaaatgg tcagtttatc ttgaggcaag ctacgggcat gtacagaatc
     6721 taattggact ttttctgcaa tcgtttgagc aatggcagat ccatccccgg tgatcatcat
     6781 caaatttttc acatcaagtt ttcttagctc cttgattgtc tttgctgctt ctgggcgaat
     6841 ctgatccgaa aataggatcg ttcctgcaaa agatcgatca attgttacat agattgctgt
     6901 attggacgtt tctatttctt cagctgaaac aaaagaggca cgtccaatct ttacttcatg
     6961 attattgact actgcttgga ttccttgacc ggtcacttct ttcagttgac taacaggata
     7021 cagttggctg tttttcacgt tgttcactaa cgaacgagct aagatatggc tagattcctg
     7081 ttctgcacta gctgcataca gaagtagctc ttcttttttt attccattga ctggctgaat
     7141 cgcctctact tccaatatcc ctttggtaag cgttcctgtt ttatcaaaag caatcgtttt
     7201 tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca acgatcccgt ttttacttga
     7261 acggctcatt cctgcaacta aagcaatggg cgcagctaga atcagtggac aaggtgatgc
     7321 cactaccagt acctcagcaa atcgtaaagg gtcttttgag aaccaccaag aaataccacc
     7381 gatcaaataa gcaatcaacg tgaaagggac tgcataacga tcagctaaac ggacaaatcg
     7441 ggcaggcttt tcttttgatt cttcgactag tttaataatc atttgatact ggctgtctgc
     7501 ggcacgtttt tcagcgatca tttggatcga tccgtctcca tttaaagacc ctgacataat
     7561 ctgatctcca ggtttcttgg tttccgggcg ggactcacct gtcaaagaag attcatcgac
     7621 cgaagattct cctttggtca ctcgaccatc tgcgggtaca agttcgccag gcttgactag
     7681 taactggtca tcaatattta tttcatcgat tactatatcc tgcaattttc cttctttgaa
     7741 tcgatgggca attcttgggg tgttatctaa caaagactgc agttctttac ccgctcgttt
     7801 attcgcgtaa tcctctagac tatctccgcc cgtaagcatg atcaatatca tcaaactagc
     7861 ccagtattct ttgacggcta atgttgcaag gattgcggta atcgctaata catctacgcc
     7921 atatcttcct gaacgtaacg tcttgatcat ttccaaaaac atcaagaagg cgagaatccc
     7981 tccagtaaat gcgacaatcg caaatgcaag ggccggctgg tgaaaaacaa attcacttaa
     8041 taaagctatc ccaccaataa gcaaagtaag taaaaatttt ttgaaatgtg tcattgtttt
     8101 ttctcctctt ttatgtgact tagagaggtt agtaataaat ttccagctgc ctctttcatc
     8161 ttaagcatag tccttgacta gcacttttta aaacaatagg ccttaattga aaacaactat
     8221 cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa aaatattcag caaggattac
     8281 tttttcgatt catcagttaa aaagtacctt ttttcgaaaa actatgctat acttttaatt
     8341 cgttatttac ggcggaagga gcaaacatgc gatgaatgag aaacaactag aacaaacgca
     8401 cgtggatgaa acgatcgaac taatccagat cgaacaaaat atgctggata caaaacaaca
     8461 agaattgact caggaaatga atcattcgac aaaagacaca gctaatcaca agattcgagc
     8521 tggttccaat gaagcttttt atgaatctgc tgttgaatat cgccaacatg agcaggaatt
     8581 gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc ctgcaaacgt tgtctgtcat
     8641 gaaagatagt ccttattttg cccgtatcga ctttaaagaa gaccgtgaaa cagaaacatt
     8701 atatctaggt atcgcttctt taagagatct ggcagaagaa acaatcgtta ttgactggcg
     8761 cgcaccaatt gccaatcttt attatgaagg tgagattggt cccgcatttt atgaaactga
     8821 aacagataga atagatgtcg atctgcagtt gaaacgacaa tttaaaatcc aagaaggacg
     8881 tattttatct atggtagata cgtcggaagt aatcaatgat gactttttgc tagagatatt
     8941 ggatgaatca tcaagcaacc atatgaaaaa catcgtctct acgatacaaa aagcacaaaa
     9001 tgcaatcatt cgggacacaa caagtaaagt aatgctgatt gaaggaatcg ccggaagtgg
     9061 aaagacatcc gctttgcttc aacgtattgc ttttctgttg tatcataatc gcaagtggct
     9121 cgaggctgaa aacgttcttc tattttcacc caaccatttg ttttctgatt acatctcgac
     9181 tgtattgcct tcattaggtg aaagcggcgt gcctacacag acattcaaaa attatttggt
     9241 gcagctgctg ccagagtttt ctttactaga tgaacagcaa caagaaagtg gttttttgct
     9301 aggggaaaaa gatccgatac aagtgatgaa aagcggattg accttagtcg atcagattga
     9361 tcgctatatc caaggcatca caaactacgg tcccttgttc cgtgatatga aaataaatgg
     9421 ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat aaagaaacaa atgaacaatt
     9481 acctttacat catagacttt ctctattaca aacgaagctc ctgaaaaaat taggcggtct
     9541 gcaaaaagac gaaacacgtc agcaatgggt caaagatctg gcggaagaac agctccaaga
     9601 actatacgca acagatccaa atcttgaata tacagaacaa aaggagcgtt cattacgtaa
     9661 aaaactggcc aaccaaatcg tacgtaaaag attccgtcga atccatcgag ggatcatgaa
     9721 ttatcaattt gtcaatataa cgaaacaata tctccacttt ctacaaactg tgccactttc
     9781 tcttctaaca cgacataaaa tcagcgagac caggtggcag gaacatttga caactgttcg
     9841 tacacacttg cgtcaaagag aattgcgtca agaggatgct gtactattct ttttactgat
     9901 gcgccgaaca tatccagtga cggttacaca caaagctcgc tatatcttta ttgatgaaat
     9961 gcaggatttc gcaccatcac aagtggcatt gctgcaagcc ttgttcccaa aagcaaattt
    10021 gactttctgt ggagatctaa atcaaaatgt ctttggaaat gaaacgatcg ttggatcatt
    10081 ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa ttaacgacaa gctatcgctc
    10141 cacaaaagaa atcactgatt ttgctaatca ttttattgtg aaagaacatc aagtagaaac
    10201 aacagcaaga aaaggagacc ttcctttgct catccaagga acaacagatg atatcaaatt
    10261 gaattggtta gcagatacca ttcgaacgac tcagggaaaa gcccggtatt ggcgtacagc
    10321 aatcatagct aaaacacaag aagaatgcga agctctttat gctcaactgc cagacgagtt
    10381 gaaacaacaa gtccagctga ttttaaatga gagtgacttt atgaagcgtt ccattatttt
    10441 acttccagcc tttttagcaa aaggtctgga gtttgaccga gttttcttgt gggatgtaga
    10501 tgcagaacat ttttcttctc agcaagacaa attgatcctt tacaccatgt gtacacgtgc
    10561 gatgcatgaa ttgacccttt ttacctccaa taatgaaagt cctttgttaa acaatatgga
    10621 tatttcatct tatgagaaaa aagtactgta agtaaaaaga caactgctat cattaatgtt
    10681 agcagttgtc tttttattta caataataat tgcagaaaaa gtaattcaat catttaaggt
    10741 catttattct atatataaat ccaaatctgt ttcaggatat tttaatttga caagcgaaat
    10801 aatcattttc agttcttcca tgttttctgg atattctggg tcaaatacct tgctatgacg
    10861 gccaatcccg ccattgtcga tcaatcggta aattcgattc cattcaatga attggtcaat
    10921 tgattggaaa ttgctgattg gatagccgcc acaatccaaa atctctgata cacgaaatgc
    10981 taggtatgca ctatcgatca ctttattttt tttcgtgtct atcttctcat ttctttcgat
    11041 aagaattttt tcaggacgat gtttcaagct ccactctaat agtagaaaga aagcctccat
    11101 ccgatactct tcttcaaata accgaaaggc tgaatcagaa cgacgaaaaa gcagcggaat
    11161 cagataattt tgtctataaa tcagcattgg tgcgcggtcc accatacact ctaaataacg
    11221 gttcagatac cctgtaccga catagtttcc taatcgatag ccttcaacgc cgaatcttgc
    11281 gtatttttgc gctaattttg aacaatcagt tacgttcaca gctaactctt ctactttgcg
    11341 gtaaccgctt aagatacgtt caaaaggttc taaagtgatt tttgcttcca tattcttccc
    11401 cgtccatctt ccacatactt catatcattt cacatgatac ttatgctctc atcataccac
    11461 aggttgaatt agaaaagaaa ataaatcaca caaaaaagca agacaatctg ttagtgagat
    11521 tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa actggttgct tagtcttcta
    11581 atgccacatt atggaacaca tgctgtacat cttctagatc ttccagtgca tcaatcattt
    11641 tttcaaatgt ttcttgatct tctggagata gtgttacctc gttttgaggg atcatttgga
    11701 tctcagcgat tgaaaaatca gtgattcctt tttcttttaa tgcttcttgt atactatgga
    11761 aatccgctac ttcaccgtaa acgatgattt gtccttcttc ttccattaca tcgcgaacat
    11821 cgatgtcttt ttccattagg tattcaagga tctcgtcagc gtcttctcct gcaaaagcaa
    11881 agattgctgt attgtcaaac atgtaagaaa ccgctccgga aacacccatg ttcccgccat
    11941 ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt cacattgttc gtcaatgtat
    12001 caacaatcac cattgagccg cttggtccaa atccttcata gcgcaattca gagtatgttt
    12061 catctcctgc accttttgct ttttcgattg ctcggtcaat aatatgtttt ggtacattat
    12121 aagttttagc gcgatcaatg acgaaacgta gtttttggtt tgcatgcgga tcaggatcac
    12181 ctgattttgc tgccgcgtag atttcaatcc caaattttgc ataaatccgg ctattattag
    12241 catctttagc agttttcttt gctacgatat ttgcccattt acgtcccata ttttcacttc
    12301 gctttctgat ttgatagttt cataacgcaa aaacgtcctg ttccattata cttgtgaatc
    12361 acgattctgt gaagcttttt ttctttcttc cttcattctt ctcattttta gtcaattatc
    12421 tatactcgga ttgggatttg cccgaaattc tgttccggaa tattgcctcc caattgatag
    12481 atttgatcac ttctaactaa cagttccgct tcttgtgcct ctttttttcc gattcgggaa
    12541 taaatagaaa tctctttttt ttcttttaag aatcttcttc cagcatcggt aaatccaagt
    12601 agtcgaagat aatttttatt ttgttggaca ggaatctctt gctttttgat attcagcaag
    12661 acataacaag ataatcgttg gatccgtgtc catgtatatc tttttgtttt tacctttgac
    12721 acaaaatcct caaaactatc agcagttgca gctgctgttt tcatgcgcga ttctattcct
    12781 tcggtcatct gatagatatc tgtcagttcc agcaaagtag aagataacaa ccgataacgc
    12841 aaatacggcc aataagattc ccaagtctgc agcgaacaag ttgaaagatc ttcttctgtc
    12901 tgaggcggca caagtccagc tattcttttt ccttcttcta acgcatggcg aatggctgtt
    12961 gcactggcta tcctctgatc tgtgatgatt ttttcatgat agcctgcact tttacgtcgg
    13021 atcggatgta attccatagg gtggacatac ttggcatttt cctttgcata acttaatccc
    13081 aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg gatacagact gcgaaaaacc
    13141 tcagtcattt tttgcggata actatacgtt tgatcagaca gttcttgaaa tgcctcttct
    13201 atcctatctt gattctcttg gacaaagcgt ccgaaactgc tgtaatcaaa cgaagtctct
    13261 tcttctgttc caaaacacaa actgtcacag tccagtgttt gcaagatttt tactgcacct
    13321 ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg gaagctccac tactaaatcc
    13381 acaccatttt gtaaagcttc attcgcgcga tgccatttat cgatgatagc cggttcgcct
    13441 ctttgcaaaa aattcccgct cattacagca atgacgacct ctgctcctgt tatttttcgt
    13501 gccatttcca catgatagcg atgtccattg tgaaaaggat tgtactctac gataatcccg
    13561 cagcttttca tgcgcatcct ccttcatagt tatcgataaa aaagaaatag agacaagtaa
    13621 aaaaaggcaa aaatcggaaa aaatacccga actatataaa ctattctcgc aaacacaata
    13681 cttctgcgac gaaaagctgc actgcaagag caatgcctat atcgttcgga tatataattt
    13741 atgttgaaga tttattcttt tcttgttaac tcgagcaggc aaaaccgcta gtctttgtat
    13801 gctacaaaga accagcgctt tgatttctct gatgctgctt cgtctgtaaa atcagaaaat
    13861 gcttcgactt tcgaaaagcc gctgttttcc agcattctta aataactttc caatggatag
    13921 gtacgctctt gatgtagttc atcttcacga ataaatcgac cagacccttc ttgttcttca
    13981 acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc ttcctggata actatcccac
    14041 aaaaaagcaa aattatcccc ttgataatga tagctatatt ctggaaaaac ctcatctact
    14101 tgataggtgg agtgtacgtc aaataaaaat cggccatttt cttctaacgc ttgatagact
    14161 tcatcaaaca cttgctgtac ctcttgtcta tttttcatat agcacagcga atcagaaaaa
    14221 caggtaattg cctgatattg tccgatttct gataaatcga gcatattgcc ttccacaaat
    14281 tggatcgatg cgtcttcttc atatgctcgc tggctggcaa tcatcaacat ctcttctgaa
    14341 aggtctaacc ctgtcacttt atatccatct tttgcaaagg caaccgctaa tgctccagta
    14401 ccgcatgcca gttccaaaat attttttgtg tcttcttgta aatgacgttt cgaaaaagct
    14461 aaccattgct gataaagtgt ttcgtccatc acttcatcgt aaatgaaagc aaatgtttca
    14521 taagccatat gttaatccaa ccattcacta agatcgacta gcggagcatc tgaccatagt
    14581 ttttccagat tatagaaatt tcgttctggc gcatggaaaa catgtacgat cacatctcca
    14641 agatcgatca atacccattt tccgccttct tttccttcaa tacgttttac ttcatatttg
    14701 ttttcttctt ctttatcaat gatttcttct gtaattgcgt tgatttgacg ttcgctattt
    14761 gctgaacaga tcatgaaata atctgccaac aaggaaacat ttcgaacgtc taaagcgata
    14821 atgtcttctg cccgttttga atctgctgct tcaatcgcaa tttttaattg ttctttacta
    14881 tctatgatga tttcctccta atatgagcag cttatttttt tgctacccag taattatatg
    14941 tttcgattgt ttttggataa atctgttgtt cttgcgcaag caaatgggcc aatgtatgtt
    15001 ttgtttcaaa tgctacagct tcgtctagat cagcccatgc aatggctcgt gcatcttgta
    15061 ccccaggaaa atctcgacct ggttcaatat agtctgctac ataaatgatt ttgtcaagga
    15121 gactcatctt agcagcccca gtcgtatgca cccggattgc atgaagaatc tctgcatcgg
    15181 tgattcctaa ttcccgctct acaaacgaag cgccaacaag accatgccag attgcattat
    15241 tataattcaa taactccgga tcaaaaccgt ctcttacgat taccattttg aactcctcat
    15301 ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat actagctttt tcaggagaag
    15361 caccgtattt tttggcaaga gccacggctg tttcttctac tccaagcaca tgcttgaagc
    15421 gttgttcgct cattctcatc tgtatttttt gcatcaggtt ttctctagaa taagcagtat
    15481 attcattact atagtccata ttcatacaac ccttcatttt gaatataatc aattacttta
    15541 tctggaacaa ggtagcggat agaacagcct tctttgatct tttgacgtat tttcgtggaa
    15601 ctgatgtcga tctcaggtac atctacccaa attacaggat atggagtatc cgttgtgtat
    15661 cctggtcgac gtatacccac aaagttgacc atagaagtca gctcatcgat tttataccat
    15721 tttggcaaat attctaccat atccccaccg ataataaagt aataatctgt atccggattg
    15781 ttttgcgtca attccttcat agtatcatag gtgtaacttt tcccaccacg agctaattca
    15841 atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta attccaacat gttgagtcga
    15901 tgttttgcat caatcgtctg tttctcatca acatgaggtg gctgataaga aggcatcaaa
    15961 aatacgcggt caagacctaa attccggcca gcttgttcag ccatcactaa atgtgcaagg
    16021 tgaacgggat tgaatgttcc gcccaagatc cctacttgct ttttcttctc taagaattga
    16081 ggcatttctt caggaaataa ttgtgaacga acaaatgtct tagcttgcgt attcatcatg
    16141 gtcactcctt atattgcttt tacttctttt gatagccttt gatacttttc ttttgtggaa
    16201 ggtttgtata atacaataac acgtccaatg atttggacga tttcgcaatc tatttctttt
    16261 tctaatactt gagctgcttc ttctgcaatc tcatctgtat tttgaagtaa cgatactttg
    16321 atcagttctc ttttttctaa agcttcttca atttgaacga tcattgctga attgatccca
    16381 ccttttccga tttgaaaaat cggctgaaga tgatgcgctt tgctacgtaa aaaacgcttt
    16441 tgttttcctc ttaaactcat aattttcctt cttccttaaa tcaatgcttt gcgtttcaat
    16501 acatctacac cctttggcgc ccagcccgca attactactg gcgctgttac agtgatccag
    16561 cctagaccgg caaaaacgat gtctgttttt tctttcacag aaaactcaaa acgaacaagc
    16621 tccggaaatg cctcgacttc atcaggacga ggaggctgta ataatccacc tacatgtttt
    16681 tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa tatttacatc atttgacaca
    16741 taagcaataa atgaagcacg attgccgctg ataaaatcaa atcttgcaag tccgcccaag
    16801 aaaagtgttt gcccttcatt cagctgataa actttaggtt tgttttcttt taacggtgca
    16861 atgatccgca aatctttttt acctaagtag tgcgccattt gatggcgatg gataattccc
    16921 ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct cgattttatc caaggtcgtt
    16981 cctggaaact gcgaagttgt gattacatct tgtactcccg ctgtattttt gatgatttga
    17041 ttgataagcg tcgattttcc gacatttgtt actccgacga tatagacatc ccgtccatcg
    17101 cggtattctt cgattttttc taatagttcc gtcatctcat gagatttctt agcactagtt
    17161 aataatacat ctactggacg aattcctgct tcgtaagcac gttccttcat ccattgtgtt
    17221 aatttagttt ttttcaatga tttaggtaat atatccactt tgttcccaac taaaagtact
    17281 ggattgtcac cgacaaaacg gtgtagtcct gggattagtg aaccattgaa gtcaaaaata
    17341 tccaccacat tgacgatcaa tgcatctttt tgccctaatt cattcagtaa gcgcaaaaag
    17401 tcgtcatccg tcaatgagac atcttgggtc tcattataat ggcgtaatct gaaacaacgc
    17461 tgacaataga cttccccgga agctaaacct ttttccaaag ccgtttgcgg cgtgtatcct
    17521 aattcaccgg gtttgtttgt ttgtataacg gcaccacagc cgatacattg taattcttct
    17581 gtcattcgat tccacctcgc cagcccatat cagggtgttt tgctaataga taggccataa
    17641 ttcttttttc ccaaaaacga ttaaattgtg tcttccaact atctgttgcg ataatgggtt
    17701 ttacaaggat gctacgtatc cctgcacgat tggctccacg tatatcagtc ataatctgat
    17761 cgcctaccat tactatctca tcatctgcta aatccaattg tttctttgct atgttgatcc
    17821 ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag atcaaatttt tcaatcgctc
    17881 gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac agggattcct gcatttttca
    17941 tttctaaaat ccaagtaagc aactcttctg ttccatctgg attattccat gcaatcaacg
    18001 tattgtctaa atcggtcaat actgctttga tgcctagatt ctttaattgg gcaggtgtaa
    18061 tctgatagat ggcttctacc atccatgttg gtttgtaatt tgaaaacatg ctgtctcctc
    18121 atctgcaaaa aatgaaggag cacataaagt actcctcaac cccgtattat actgcatatc
    18181 agcaaaaaaa actacctcta tactcgttcg tctttcagaa aaagcatttc tttacaaaat
    18241 gaccaaaaat aaagattgat cacagaaaaa tttagaaaca aaaaacaact aatattggcg
    18301 gaacctcttg tatcgttttt ccagtaattt atgctgatct aatcgaacaa gttccgtcaa
    18361 tctttcaatc aacgcttttt tcataatgtg tgcgacttta tatcgtggca actgctcgcc
    18421 gttgaacgtt tcaggaataa ctcgatcaac gattcctaac tcgcgtagtt ctggcgcagt
    18481 aattttcatc aactcagctg cttctgcggc gcgactaccg tctttccaca aaatcgacgc
    18541 aaatccttct ggagaaagca cagcataaat cgtttcttcc agcatccaga cttcatccgc
    18601 taaacctaga gcaagggcac cgccacttcc accttcacca atgatgatgg cgatgatcgg
    18661 tacctttaaa tcagacattt cgagcagatt tctggcaata gcctctcctt cgccgcgctc
    18721 ttctgctcct acaccgcaat atgcacctgc tgtattgatc aaggtaatca ccggtctatt
    18781 gaacttttcc gcttgtttca tcagtcgtaa agcttttcga tagccttcag gatggggaga
    18841 accaaaattt ctgcggatat tttcctgcag atcccgtcct ttttgaatac cgatcactgt
    18901 taccggtttg ccatctaatc gagcgattcc accaacaatc gcttcgtcat ctgcaaataa
    18961 acgatcacca tggcattcct cgaaagaatc gaagatctct tcaaaaaaat ccaagcttgt
    19021 ccatcgttct ttagctcttg ctaactgaac gacatcatgt gctgtcttat ccacgatcta
    19081 tccatccttt ctgtgtatgc aattcaagaa gcgtatggat tttctgtttc aattccatgc
    19141 ggggaacaat ctgatcgaca aaaccatgag ataataagaa ttcagccttt tggaaatctt
    19201 ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct tccagcaaaa ccgatcaagc
    19261 tttggggttc tgctagaata atatcgcctt ccattgcaaa actggcagtt actcctccgg
    19321 tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc attgctatgc cgtttgacag
    19381 cagcagagat ttttgccatc tgcattagag aaaagattcc ttcttgcatc cgtgcgccac
    19441 ctgaagctgt gaacaagacg actggaagac tttcctttgt tgctcgttcg aataatctgg
    19501 tgatcttttc tccgacaatc gttcccatac ttcccatgat aaaattagga tccatcactc
    19561 caataatgaa gggaatcccc tgaatggttg ctttaccagt gaggactgct tcatgaagtc
    19621 ctgttttatc ttgcattttt ttaatttttt ccgtatattc gggaaatgct agcggatctt
    19681 tggttacaag atccgtatcc cattcttcaa aacttttttc atcaataatc aaagctagac
    19741 gctgccatgc accgattcga aaagcgtatc cgcaatgagg gcatactttt tcttcaccga
    19801 tgtctttcgt ataaaggata tgtttgcaat ttggacactt tgcccacatg ttatcaggaa
    19861 cagatggcga gttagcaggt ttgctctctc tattaggatt gatccgaata tatttctttt
    19921 tcttaaacag agccatctat gcgcctccta tctccgtttc tggtgtccaa ttcggtaaaa
    19981 attcttcttg taaaaatgct gtgctgtaat cacctgctat gactgcagga tgactaatca
    20041 aatccatctg aaattctgcg ttcgtgatga ttccttctgt gataaattca cttaaggctc
    20101 gctgcatctt cattaatgct tcaaaacgcg tatttccatg gacgattatt tttgcaatca
    20161 ttgaatcata atatggcggg atcgtatatc ccgggtaaac tgcactgtct actcgcagtc
    20221 ccatcccacc tgctggaagc agtaagtttt ggatcttccc tggagaagga gcaaaatgga
    20281 aagcaggatt ttctgcatta atccggcatt cgattgcgtg tccttggaat actacttctt
    20341 cttgacacac attcaaaggc tcaccggctg ctatctccac ctgttttttt actaaatcga
    20401 ttcctgtgac catttctgtt actggatgtt ccacttggat tcgagtattc atttccatga
    20461 aataaaaatc gccttcttca tccatcagaa actcgatcgt tccggcattt tcataattga
    20521 ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc tctttttgtt tgtgagatca
    20581 ctacagaagg agattcttcc agtacttttt gattgttgcg ttgtaaagaa caatctcgct
    20641 cgcctaaatg aatgacatga ccaaatcgat cacctaagat ctgaacttct atatggcgag
    20701 caggataaat gattttttcc aaatacatat catcatttcc aaatgccgct gctgcttctt
    20761 gctgagctga agaaaaatgc tgtgggagct cttcttttga ttgaactttc cgaatgcctt
    20821 tcccgccacc acctgcagct gctttcagca tcactggata accaattctg tctgctattt
    20881 ccaatgcttc ttctactgta gataatacac cagtacttcc tggaatgact gggacatttg
    20941 cttcttgcat caattgacgc gcattgatct tatttcccat tgcatcgatc gttgcacttt
    21001 taggaccaat aaatgtgata ttgcactctt cacacatgga ggcaaatcgg ctattttcag
    21061 ataaaaaacc aaatcctgga tgaattgctt cggcttttgt cacgattgca gcgctcagta
    21121 cttcctgaac attcagatat gaatcaacgg cttttgccgg gccaatgcag attgcttcat
    21181 ctgctaactg tgtatgaagt gcttcggcat ctgcttctga atatatcgct acggtttgga
    21241 tccctagttc gcggcatgca cgaatgatac gtacagcgat ttcaccgcgg ttagctatca
    21301 atactttaga aaacatattt cacctatcca atcataaagg ttaattccgc ttcggctact
    21361 tttttaccgt ctactttagc gattcctttg cctattccgg ctgaagcttt cactttcaat
    21421 atctcaactt caaggtataa ggtatctccc ggtgtaactt tcttacggaa ttttgctttg
    21481 tccaatccgc cgaaataagc cgtctttccc ttgaattgtt caagagaaag taatgcaact
    21541 gctcctgctt gagccattgc ttcaacaatc aatacccctg gcataacagg ttcttctgga
    21601 aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt tcttagcaac gatccgttct
    21661 ccttcaacca tttcttccac tcgatcaatc aaaagcattg gataacgatg tggaatgatt
    21721 tcttttattt cttgtatgtt cattgttttc cctctttcct gctttgctta tttttgctga
    21781 atcctaaaga gtggctgtcc atattcgaca actgactcgt tttctacaag gatttctgtg
    21841 atcactccgt cggcctcact agttatctca ttcatcagtt tcatcgcttc aataatgcag
    21901 ataacttctc ctttggcaac ttgatcacct acttttttga aagctggttt gtcgggcgct
    21961 ggttgcagat aaacgattcc cacgattggc gaaacaacct cgattccatc aaatactgcc
    22021 gattcttttt ctttcattat ttctggagca gttgttgctt gttcaggtat gacattgact
    22081 ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat tcatgcctcg acttgtttta
    22141 tttttattca tatacaattc aaattgacct tcacgcaaat cgaattccgt tagcgaggat
    22201 tgatcaaatt gactgactaa ttctctgatt tcattgatat ccaaaattat tcctcccagc
    22261 gtttcatgca cagaaccgca ttatgtccgc caaaccctaa tgaattactc attgcataag
    22321 taaaacttgc aggtttgctt tcgtttttga caactgtcaa gtcaatctca ggatcttgtt
    22381 tttctacatt gatcgtaggt gggataaatt gatgttctaa tgccagcaaa gttgccaagg
    22441 cttcgatccc gccggctgct cccaataaat gtccagtcat cgatttcgtg ctgctgacgt
    22501 aagtatctct gaaattttca cctaatgcga tttggattgc ttttgcttct gcctggtcat
    22561 tggctggtgt acttgttccg tgagcattga tatatccgac ttgttccggc tgtacaccag
    22621 cttcttccat cgcaagcttc attgctttag atgcaccaga accatctgga gtaggagctg
    22681 tcatatggta agcgtcacag tttgcaccgt atccaacgat ttctccatag attttggcac
    22741 cgcgagcttg tgcatgttct aaagattcaa gaactagaac gcctgctcct tcacccatca
    22801 caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg attaggatca gttgattctg
    22861 agagtgctgt taaagctgca aatccagcaa tccccatctc acaaatcgtt gcttctgttc
    22921 ctccagcaag aatgacatca gaatagccat gtttgatgtt acggaatgct tccccaattg
    22981 aattcgttcc gctagcacaa gctgttacga tagctgtaca aatacctttt gcacctacac
    23041 gcaaagcaat atttccagct gccatgttgg caatcgccat tggtacgaac attggagaaa
    23101 ctcgttttgc acctttttca tgtagacgaa taacttggtt ttcgattgtt ggaagaccac
    23161 cgatcccaga tccgatgatg acgccaaacc ggtcttgatt cattttttct ttatctaaac
    23221 cgctcatctc cattgcttct aaagcagcgt agattccata gatcgaaaac atatccattc
    23281 gtttgctatc ttttttaata aaatatttat cgtaagggaa atctttgact tcacccgcta
    23341 aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg tgcgatgcca ttcgtcccct
    23401 cttttaagct attcaaaaag ctgtctgcgt catttccaat aggtgaagtg actccatagc
    23461 cagtaattac cactcgattc atttgtttgc tctccttttc ttatccgtgc atgaccaatc
    23521 cgccatcgac attgatgact tgtccggtga tatatggatt ttgtgctaag aaaactgctg
    23581 tttgtgcaat atcttctact tgtccgaaac gctgcatcgg aatttgcttt tccgcttgtt
    23641 ccttgacttt gtctgctaaa acttccgtca tatcagttgt gatgaatcct ggcgcaatgg
    23701 cattacatgt aatgcctcta gttgcagctt ctcgtgccac agattttgtt aatcctacta
    23761 cgccagcttt actagctgca taatttgctt gaccaatatt tccaatcaac ccagatacac
    23821 tagagagatt aatgatggcc ccttctcgct gcttcatcat ttttttcaat acgtgctgcg
    23881 tcatattgaa ggttccaatc aaattgatat ccagacattt tttgaaatct tctgcatcca
    23941 ttcgcatcac aagtttgtca tttgtgattc cggcattgtt tactaacaca tggatcgatc
    24001 caagcttttc ttctgcttct ttgatcattt gtcccgcttt ctcataatca gagatgtcac
    24061 cggaaactcc tacgcatttt acaccgaatg cttcgatttc ttctatcttt tcttttggaa
    24121 tctctccgcg accattcaaa atgatatttg ctccagcttt tgcaaaagct aaggccatcg
    24181 ctttgccgat tcctcttgta ctacctgtga taaatacatt ttttcctttt acatccataa
    24241 cgttcctcct tatagtattg ctattgtttc atcaaatgtc tgcttattct caacacgcag
    24301 aactggtatt gttttatcga tttttttcat aaatccgctt aatacttttc cggggccgac
    24361 ttcgatgact tgttcgatgc cgattgtttt taacttatgg atactctcat agaaacgaac
    24421 aggttgcatg acttgctgtt caagtagtcc cgcgattgtt tctttcttca ttatttccgt
    24481 tgttgtgttg cttatgatag gaaaagaagg ttcagagaat tgaatctgac ttaggtcctt
    24541 cgccagtttt tttgctgccg gttctaaaat agctgtatga aaaggcccgc tgacatttag
    24601 agggatcatt cttttgaacc ctttttcttt taatagtaaa acagcttcgt ctactgcttt
    24661 ttcttcgcca ccaatcacga tctgctgagg tgtattataa tttgcaggag atacgatgcc
    24721 gtacttgcta gcttcatgac agctttcctc gatcgtttca atcggcgcat tcatcactgc
    24781 aaccattttc ccgcttccag ctggggcagc ttctgtcata taagcgcctc tttttgctac
    24841 taacgcaact gcttcagtga aggatagcgc attactagct actaatgccg aatattctcc
    24901 taaactcagt cctaaagctg catctgggat gattccatgc tccttcaata agcgataata
    24961 cgcgatgctg actgttagaa tagctggctg tgtatattgc gtctgatcca aacgttcatt
    25021 ttctgtaaag caaagttcag ccatatcgta gccgagaatc tcacttgctt catcaaatgt
    25081 ctgctttaca acggcttctt catataaatc ttttcccata ccttgatatt gtgcaccttg
    25141 gccactaaat aagaatgctg ttttcatgtt tttctccaat atatccagaa tatatgtttg
    25201 attcttccta ttcaaaaagg ccgagacatt cctatttcag gaaatgtccc agcccccaac
    25261 ctaattttaa tgattatgca gtttgttttt ctacgtaagt cactaaatct tgaaccgttt
    25321 tgattccgtc ttctgtttcg attttcacgt caaattcatc ttcaatttca ttgatgattt
    25381 ggaataaatc caagctgtca gcttctaagt cttcttggat gtcagtagtc aatttgattt
    25441 cttcagtttc ttttcctaat tcttctgcga tgatttcttg aattttttcg aataccataa
    25501 taatatattc ctccgatatt gtttgctttt tatttttata atttaacagt ctacaactcc
    25561 atgagaatac ttccccatgt taaacctccg ccatagcctg taaatattac tttctgctgt
    25621 tttcctaagg tgatctttcc actagaaact gcttcatcca ataagatagg gatgcttgca
    25681 gcagatgtat tcccatattt atccatattg gtcaggaact tttcttgcgg catctttact
    25741 tttcgggcaa ttttctcaat aattctgagg tttgcctgat gcaaaagcag ataatcaact
    25801 ggtttgtctt tcatgacttc ttggatattg tttgcaacgt ctcgtacggc aaaatcaaaa
    25861 atatctctgc cagtcatttg caaataatac gaaccttctg aatcttctga atagaacgga
    25921 tttttatttt gctggtagcc agcggtcaat gagctacttc tggtaccgtc agctgctaat
    25981 ttttctttca gcaatttttt ctgtggattc gcttctaaga gaatcccacc tgctccatcg
    26041 ccaaacaaca cagcagtcgt acgatcagac caatcgatta gcttagatag tgtttcacca
    26101 ccaatcacca gtcccttagt tgagccgcag cggatcattt tttcagccat gcttaacgca
    26161 taaacaaatc ctgagcacgc agcactgata tcaaaagcga tagcatgagt tgctcccaat
    26221 ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat cgggcgacat tgttgctact
    26281 aaaataaaat ccaaatcttt agggtttaga tttttctgtt ttatcaattt ttccgccact
    26341 aaaatgcata aatcagaagt ctcctgattt gttacacatc ttcgttcacg aatacccgtc
    26401 cttgacgaaa tccattcatc agaggtatcc atcatcttgg aaagatcatt attagtaata
    26461 atcttttcag gaaggacgct ggctgttgca gtaatcattc caaattgttc cattaaatat
    26521 cctcacttat agtcttgcaa gaagtcgtgc aagtttttca gtgcatccag caaggcatgc
    26581 tgttcctccg tagccattcc gtctaagatg ttcttgacca tttcacgatg aaaatgctga
    26641 tggacccgaa atagtaactt tccttttttc gttagtccca actttacaac gcggcggtca
    26701 tcttcactgc ggatacgttc gacatagcct ttttttacta acttgttaat agcagtggtc
    26761 aaggtcccaa cagtaattga tagttctttg gctacttctg aagttgtttt tttcttgtac
    26821 atcccgattg cctcgatcgt gtgcatctct gtgattgaca gatctttgaa ttgagatttt
    26881 ttcagctcag actcttcgat tgtcaaaata tcattgaaga cactaacaag ataatcattt
    26941 actgttttta aatctggttc catgttccac cgtccactaa ttagtttgat tatcaaatct
    27001 tttgatgttc aaactatatc ttaacttttt tcaaaatgca accttaaaag atcatttttt
    27061 tactatatga gcttttttta agattttact catttaaaac aactgataaa tcagcattta
    27121 taatttcttt tattagaaaa atcatctatc tcacatattt tgattatcaa agtattttct
    27181 gtgaacagaa ctatagaatt ccctaaaact tgtccattat ttcaaaattt gttatagtct
    27241 ttttattcaa agcgtaaaag gagatcctat gttaaaagaa aaaatgaaaa ctctccccat
    27301 gctgccgggt gtctatctta tgaaagaccg agatggtaag gtcatctatg ttggtaaagc
    27361 aaaacggctc aaaaatagag taagcagcta ttttcatcag aataaacagc attcaaaaaa
    27421 agtattacgt atgattcatc atataacaga ttttgatttc gtcgtagtag acacggaatt
    27481 agatgcttta ttgctcgagt gtcaattgat ccaacattac cgtccttttt ataaccgaca
    27541 aatgaattat ttcagtaatt ataattatgt acatattacc aataagggat ttgtattaac
    27601 agatactcct acggctcgaa catacgggcc ttttcgtctc tataaaaaaa tgccgtctat
    27661 tttgcgtata atggaagaaa cttatcaaat gccttggttg tctgaaatta gtttgttagc
    27721 tttgcgagtc cagcttcctg acctacagga aatgactttt gaacagaaaa aaaaggaact
    27781 ccaagggctg tttcaaggcc gaaataaaaa gctactgact tacttgaaaa aaagacaaca
    27841 acatttcatc tatcagttga atttcgaaaa agccggtatg cttcaaaaag atatcgaatt
    27901 agttacttat tttattagac ggatccagga acaaaagcag tttttaagaa caccatcgct
    27961 caccttcagc atgccattag cagcagatga gagtcagaaa aagcactacc tcgtttgtta
    28021 tggtcaactt gcagaaacaa tgattacctc tggtgacgtt tctcctgact tctattatga
    28081 aaagaaagaa gctcatttat ctttgaaacg tcaattgtca aaagaagaaa tcgatcctgt
    28141 acaaatcttg atcagttacc gcaaaaaatt agaaaaagaa cagtttgaaa ttgaactgtt
    28201 aaacaaaaaa gaagctgaaa agcaactaaa ttagttgctt ctcggcttct tttaggcatc
    28261 ttcaacttca aatgtcaatt atcctaaaat ttattggatt aagtcataga tttccatcgc
    28321 tacgatatcg atattatcaa attcgtattg ctgatgagta tctgtttcag ttaattcaaa
    28381 tgtatcggtc gctttatcat aagttactgt acacttctct acgccttctt tttcaaaacg
    28441 gcgaacttgc agttcattat ctgctgactc gaccatagcc tccagtcgtt ttatgattgc
    28501 gactaattgt gaatgtgtca tcggaggtcc tccttttctt atttctgtta tattgtatca
    28561 aaagcatagc ctacttgcat tgattttctc taaaaaaact cgttttttat gatttttttt
    28621 ctggtatttt tccttcaggc caccaaagtt tgatcaaagc ttgggttccg tcattctcaa
    28681 aacctttatc tgccaactct tcatatagtt tcaatgcttg ggtagttgct ggcaatacaa
    28741 gatccatttt ttctgcttct tctaatgcaa tctttaaatc tttgataaaa tgtttgacaa
    28801 aaaaaccagg tgtgtaatct tcttttaaaa tacgaggaga ataattgctt aaagaccagt
    28861 tagctgcact tccacctgaa agcgtctcaa tcactttctt taaatcaagt ccgttttttt
    28921 gtgcatagac aagcatttcc gtcattcctg tcatcgtacc tgcaatcatg atctgattag
    28981 ccatttttgt atgctgacct ttcccagcag aaccatgcaa tgtaaatgtc gtaccaaatt
    29041 ctttgaataa aggcagtact tgatcataaa cggcttcttc tccaccgacc atgatcgtca
    29101 gtgtaccatt ctttgctcct aagtcaccac cggataccgg tgcatctaac gcatctgcgc
    29161 ctttttcttt tgctgttttt gcaatttttt ctgccaggct tggtgtactt gtagtcaaat
    29221 caactaaaat atgtcctgag atatctgcag aaaaaatccc cgactgtcca tagtagattt
    29281 cttctacatc tttggggtaa cctaccattg taaagagaat attactttgt tctgctaccg
    29341 cttttggtgt atctgcccag atagctcctt ctgttactaa aggatcagct tttgcttttg
    29401 tccgattata gacagctact tcgtgtcctg cttctagtag atggcgtgcg acagcacttc
    29461 ccatgacgcc tgttccgata aaaccaagtt tcattttttc gacctcctaa aaatcaaaaa
    29521 tccttgcttc tatgctagta tacgctagaa acaaggattt tttcataaaa aatgtttgaa
    29581 ttttatcttt taaatgaatt taattttatt ttgattcgtt caatcgagtc ttcttcttct
    29641 tttcttcgca tctcttcttc atgataaaca accatgtctt gataaaattc gatcatagct
    29701 tcgccgaaat gtgtagatga aatatcataa agtttagctt ctaaaacttt tggatcttta
    29761 ggaacttcac tggaaatata atcaataagt gctggtgcaa agtcttcgtc ggtttcaaaa
    29821 gttttcccta atgaaggatg atcgaacaat cggttcaaat aagcatttcc ttccacgaca
    29881 caaggtgttc cggctgccat cgcttctgta taagtaagcc cttgtgtttc tgaagtagaa
    29941 gcactgacaa aataatctgc cgctttataa taaagtgcta catcattgtt gtccacttct
    30001 cctgtgaact gcacaaattc ttctaactgc agttctgaga tcaattcctc taactcttct
    30061 acataaggtc cttttcctac gataactaat ctggcgttag gataagcgga gatgacctga
    30121 ggaaacccat taatcaaggc ttggatattt ttctcataag aaatcctgct taaagaaaga
    30181 atcatcaaat ggttttcctg aagacctagt gactccctta atttgctgat atcctgctga
    30241 gtgatatcag aacgtttgaa tttttcaatg tcgataccag taggaatcac gcgaagcggt
    30301 gctattacac catagctgcg taatgtatca ataacacgtt cacttggaca aactacacct
    30361 gtcgtatgat ttgcaaataa tctagacaag tattttacat gggattgcct gatcactttt
    30421 cctttaccga tataatgaag gtagtcttca tacatcgtat ggtaagtatg gatcagaggt
    30481 attttcaact tcttagctac catcttccca agtatccctg ctccgaattc tgtatgggta
    30541 tgaataagat ctagttctag ttctttggca accaaataag cataccacat gcctctaaca
    30601 acaactcttc gatccttgaa agaaataaat ggtacacttg gcattcgaat cacatctttt
    30661 tccaacttat ccgcattagg atcggtcgtt gtaaaaatat agacttcatg cccatgtctt
    30721 tctaattctt gttttaatgt tttgatcgat gtagcaactc cgctgacttg cggaaagtag
    30781 gtatcggtaa aaaagccgat tttcatgttt ttcgcctcca aactagtcct tgacctgatt
    30841 tacttttttt aatttgctag agactttttc attcagtaca ctttcgtata catttttaag
    30901 ttcttcaccg attttattga tacttcgctc ttttgctgtt tgataaccgg cttgtgtcgt
    30961 actcggtagt tcttgattgg taatctgttg gatcagtcgg ataaattctt cgtttgtctt
    31021 ccccatatag cagttcttgc tatcttctaa ccagccatta tacactggaa tatctcgaac
    31081 aagtacgttt tgtttgcttg ctaaagcttc taaaacaacg atcccttctg tctcttcata
    31141 agaagggaaa aagaatagat ctgcacctga atacgcacct tctatgatct ctccacgaat
    31201 gtaaccagga aacaggacat tttcaggatg atcttctttt acaattttcc ggatgttccg
    31261 aggaatcgag tacatgggaa catgaccaaa ccaaataaat gtgtattcgg gcatcttctt
    31321 agcaatttct acgaaatcaa tgattccttt acgttcgaaa aacaaaccga cacaaatgat
    31381 tactttttga tccggagaca gtttgaaata ttctctgaac ttttgttctt tcattggatc
    31441 agggtgatat ttctctaagt cgatcccatt ggaaatagct tgaatcggca cacggatacc
    31501 atagctttcc aacaactgtt ttgaataagg tgttggcgtg atcagatagt ccgctttttg
    31561 gtacaatcct accagatatt tttttacgat aggagaaagc tggttcgatc cgataaagga
    31621 atttcggaaa tcttcctctg tagaatgcgc atgatagaca actttttttc cttctcttct
    31681 ggctttattg accatattat gactattgat tccgtatgta ttgatgtgca ggatgtcata
    31741 atcttctttt tcatctagtg tataagagat accgacttcc gtcagagcac gtttttgatg
    31801 atcaagcgca cgcccgattc cagattttgc aagcatcttt tcactttcaa aatataataa
    31861 taccttcacc ttacgtcccc cttcacttat atagtataac atagcctaca aactgtcact
    31921 caaacttaag ccctattttt gtctattctt actgacaaaa acgttttctt aaaaaagaac
    31981 aaaaaaactg gcgtagctct tttacaagcc acaccagctt ttgatacgtt gtttatttta
    32041 catattcatg aacaagttca acgacttctt ccatcatatc gcattctttc aatgcacgat
    32101 cagcaagttc agccattttc gctgtgtcca agcgtttcat taaactacgc gttttaagaa
    32161 tagatgtcgc actcattgag aactcatcta gacccatacc tactagcaat ggaacagctg
    32221 tttgatctcc agccatttct ccacacatac ctgcccattt tccttcagcg tgtgctgcat
    32281 caattacatt tttgatcaaa cgtaaaattg atgggttata tggttggtac aagtaagaaa
    32341 cgcgttcgtt catacggtct gctgccattg tgtattgaat caaatcgttc gtacctacag
    32401 agaagaaatc tacttctttt gcaaacttgt ctgctaagac tgctgctgct ggaatctcga
    32461 tcatgatgcc gacttggatc gtatcagata cttccttgcc ttcacttatc aatttttgtt
    32521 tttcttcttc aaagatcgct tttgctgcgc ggaattcttt gagtgtagct accataggga
    32581 acatgatacg taaattacca tgaacagatg cacgaagcaa tgcacgcatt tgtgtacgga
    32641 acatttcgtc gccttgttca gataaactga tacgcaatgc acgatatcct aagaatggat
    32701 tcatttcatg aggtaattgc agatatggta gttctttatc tccaccgatg tccattgtac
    32761 gaacaactac aggttttcct tccatacctt ctaatacagc tttgtaagct tcatattggt
    32821 catcttctgt tgggaagtct ggagaatcca tatacaggaa ttcagtacgg tacagaccaa
    32881 ctgcttctcc accattatta tggacaccaa ctagatcttt tggtgttccg atgtttgcag
    32941 ctaattcaaa atgcttgccg tcagctgtga cagtttctgc attttttaat ttttcccatt
    33001 ctgctttttg tgctgcgtaa tctgcacctg ctttttcaaa ttcagctttt tgttcatctg
    33061 taggatcgat gattacatcg ccttcgatcc cgttgacagc caaaatatcg ccttctttga
    33121 ctttagcagt aatttctttt gtcccaacga ttgctggaat ttctaaagaa cgtgccatga
    33181 tagcagaatg tgaagtacgt ccaccaatgt ctgttacaaa cgcttttaca aaattgcgat
    33241 ctaattgtgc tgtatcactt ggagtcaagt catgtgcaac aacgaccact tcttcgttga
    33301 tcattgatgg atttggtaaa gtaacgccta ataagtgcgc taaaatacgt ttagcaacgt
    33361 cacgaatatc tgcagcacgc tcttgcatat aagcattatc ttccattgct tcgaacatac
    33421 cgatatacat atccgttact tcttttagcg ctgattcagc atttacgctg ttgtctttaa
    33481 tattttgctt gatttgacct accatttctg gatctgaaag aaccatcaaa tgggcatcaa
    33541 atacttgcgc ttctgcttca cctaagcttt gcgctgcttt ttcacgaatt tgctgcaatt
    33601 cttcagtaga tttagctaat gcagcatcca aacgagcttc ttcagccgca gtatcttcta
    33661 ctgttgcctt actgaatgtt aaatccggtt gaactagcag gtaagctttt gcaacggcta
    33721 caccgtcact agcggcaatc ccttttagca tttcaaccat tattcagata agccttcttt
    33781 cttcattgtt tcaacgattg ctgccattgc atcagcttcg tcagcacctt ctgcagtaat
    33841 agtaacatca gaaccttgac ctacacctaa agacataacg cccatgattg atttcaagtt
    33901 tactgattta cctttatact ctaagtttac atcagagtta aatttgcttg ctgtttgtac
    33961 taatagtgta gctggacgag cgtggatccc agtttctgct actacgtgaa attctttctt
    34021 ttccatatta atcggtctcc tttaagtgag tgttgttttt atgtgagggt tttctttttt
    34081 agtaattcag agaatcctaa caaatgccac cctttcatct gtaaagatta acattttttt
    34141 tcgttagata caacagtttt cattcaattt cagataaaag tattcaaatt attccggatt
    34201 ctttttcatc cttttcttca cattttataa caaacgtgtt tatttccttt ttcttgtcgc
    34261 tttctcttct cctgacgttt atcattcttt cctttgaccc tctttgtttt catatgaaac
    34321 gaattacttg cttccctttt tatttttagt ataataagag tcaaaggtca ggaatggtca
    34381 atagagattt caccttttct acctcataaa tctcttaaaa aactaggggt tattctttta
    34441 cctcatgaaa aacgagatgt aaaatatgga tgtacccatt tttgtgaaag gacgtgaatg
    34501 attcatgctt tgtcaaaact gcggcaagaa tgaggcaacg attcacttgt atgccactgt
    34561 caatggtcag cggacacaac tcgattactg tcagagctgt tatcaaaaaa tcaaaaatca
    34621 acaaaatgga ggtctgacta atatggccca aaatgatcca tttggatttg gcagtttgga
    34681 cgatcttttc cgttccatgt ctcgccaaat gcaacagcaa ggaaattatg agcaaacacc
    34741 accaacacaa tttggcggaa acaacaactt caatggtggt cagccacctc aaggcaatac
    34801 agaaggttta ttgggagaat acggaatcaa tatcacagaa caagcacgac aaggtgatat
    34861 cgatcctgtg atcggacgcg atgacgaaat caaacgagtc attgaaattt taaatcgccg
    34921 aaccaagaac aatcctgtct tgattggaga accaggtgtt ggtaaaacag cagttgttga
    34981 aggtttagca caaaaaatcg tagatggtga tgtaccgcaa aaattaatgg acaaagaagt
    35041 cattcgttta gatgtcgtat ctttagtcca aggtactggt atacgaggac aatttgaaga
    35101 acgtatgcaa aaattgattg aagagatccg tcaagcagaa aatgtgatcc tattcataga
    35161 tgaagttcac gaaatcgtcg gtgctggttc tgctggtgat ggaaatatgg atgctggtaa
    35221 tattttaaaa ccagctttag ctcgaggaga attgcaaatg gttggtgcta ctaccttaaa
    35281 tgagtaccgc atcatcgaaa aagacgctgc tttagaacgt cgtatgcaac ctgtacgggt
    35341 agatgaacca actgtcgaag aaacgatcag tattttgaaa ggtttgcaaa aacgttatga
    35401 agactatcat catgtaaaat atactgatga ggccatcgaa gcagccgcaa ctttatccaa
    35461 tcgttacgtc caagatcgct tcttgccgga taaagccatc gatttgctag atgaaacagg
    35521 ttctaagaaa aacttgacga tccaaatcgt tgatcctaaa acaatcgaga aaaaactgca
    35581 agaagcagaa gaacaaaaag ttttagcttc tcgagaagaa gatttcgaaa aagcagctta
    35641 ttatcgcgat cagatcaata aacttcaaaa aatgaaagaa cgtcagctca ctgaagagga
    35701 aacacctgtg attaccgaaa aagatatgga aaaaatcgtt gaacaacgga caggtattcc
    35761 agtgggtgaa ttaaaagaaa aagaacagac acaactgaaa aacttagcag atgacttgaa
    35821 agctcatgtc atcggacaag ataacgctgt agatcgagta gcgaaagcga ttcgccgaaa
    35881 ccgtgttgga ttaaacaaac agaatcgtcc aatcggctcc ttcttatttg ttggaccaac
    35941 tggtgtaggt aaaacagagc ttgcgaaaca acttgcctac gaactattcg gttcacaaga
    36001 ttcaatgatt cgtttcgata tgtctgaata tatggaaaaa catagtgtct ctaaattgat
    36061 tggttctcct ccaggttatg tcggatacga agaagctggt caattaacag aaaaagtacg
    36121 gagaaatcct tacagtcttg tcttgttaga tgaagtagaa aaagctcatc cagatgtttt
    36181 gcatatgttc ttgcaaatct tagatgatgg tcgattgaca gatgcacaag gaagaacggt
    36241 cagctttaaa gatacgatca tcattatgac aagtaatgcc ggaactggta aagtagaagc
    36301 aaacgttggt tttggtgcgg cacgcgaagg tgttactcgt tctgtattga accaattaaa
    36361 caactacttt acaccagaat ttctgaaccg ttttgacggg atcatcgaat tcagtgcatt
    36421 atcaaaagaa aacttgatga caatcgtcac actaatgcta gacgatgtca accaaatgct
    36481 ggcagcacag caacttcaca tcgaagttcc tacgaatgtc aaagaaaaat tagttgactt
    36541 aggctatgat ccatctatgg gtgctcgtcc tcttcgacgc acgatccaag aacaaatcga
    36601 agatggtatc gctgaatttt atcttgatca cccttctatc catgagttga aagcaaaact
    36661 ggataaagat ggaaaaatca tcgttacttc taaaccagaa cgtttggcta aagaatcagc
    36721 cgaagaaacg gctgaataaa tccagtttta tagcgtgaga cggtatttct ttgagaaatg
    36781 ccgtctcatt cttttttcag aaaagtcaaa atactgttca ttttataaaa aagaaattat
    36841 aataagagaa acaagcaatt aaaaatacat aaaagaggtg agcgccatga aattggtaaa
    36901 tgtaacaaac agccattccc gtcttgtatt aaaccagctt gaaaacactg atgcccatct
    36961 agtcaaggtc tacacagccg gaaataccac tattgtctac actgaagccc ctgaacataa
    37021 tgaaattctg ctgatcaatg acaaacgtaa aatccagccg aaagaaatcg aagatgctaa
    37081 aaattatttc ttagataaaa tcaaagacgc cgtttaccac gaggatgaaa tcaaagtaat
    37141 cgaattggca ggccttgttg aaatctcgat tccaaaacat gaattaggcg ctacattagc
    37201 cgtgtaaaca aattttgaac ataataatta aagagcgtgg gacaaaagta aagaacactt
    37261 ttgtctcacg ctctaaacac gtataaacgg cgaaagcaga agcaactcct tcggaaataa
    37321 gctgaaattc acgaaaattg cttttcaaat ttttgtgaat tccagcttat ttcttggagt
    37381 taaacgcttc tgtctcagcc tctttttctt tctagctttt tgatttttct cttttctttt
    37441 gtacttttct cttttcattt tcagttctac gcgtgtcttt atttttaact ttttcctctt
    37501 tatggatgat tgatcgtact ttttgtgcaa tttgctcgtt tttgtcccag tcttttacat
    37561 ctaataatcg acataatcgt aacatctctt cttttttctg tttttttctt tcacgtcttt
    37621 gccattctgt ttccatgtgt cacactctcc tttctttaat catatgtacg caaaataatt
    37681 tttatatttt tttgattaga catttctatg attttaatat agtaaaaaga gccgtcacgg
    37741 aaaatccgtc acggctctaa acaaaatatg agaggctgtt tttgtttggc tattcttatt
    37801 acttgatgca gggcagcttg tgtcaagact tctttacatc aaacttttta attttacatt
    37861 gggatattta tccgcaaacc agcgttctgc aaattggttc tcgaataaga acaacggttg
    37921 gtcgaaacgg tcacgagcca agatattgcg acttgaactc atcttctcat ccaaatcttc
    37981 tggatcgatc cagcgagcga ttttgtgtcc cattggagac atgattactt cggcgttata
    38041 ctcatttaac atacgatatt ggaatacttc gaattgtagc tgaccaacag ctccaatgat
    38101 atattcttcc gttagatatg ttttataaag ctgaatcgct ccttcttgaa ctaattgata
    38161 gattcctttg tggaaggatt tttgtttcat gacatttttt gcagtcactt tcataaacag
    38221 ctctggagta aatgaaggga gttcttcata agcaactttt agttttcctt cgaacaatgt
    38281 atccccaatc tgataattgc ctgtatcata tacaccgatg atatcgcctg ctactgcttt
    38341 ttcgacgttt tctctcgaat ctgccataaa ttgtgtgaca ttgcttaatt tcagtttttt
    38401 atttgtacgt tccaaccaga catccattcc tcgttcgaat gttccagaac agattcggac
    38461 aaaagcgatt cggtcacgat gggctggatt catatttgct tggatcttga atacgaaacc
    38521 tgaaaattct tcctcataag gacttaccat ctgatcatct tgtgttttgt gtccataagg
    38581 agctggtgcc aattcaacga aagtctctaa aaaagtctgt acaccgaagt tagtcaatgc
    38641 agaaccaaaa aatactggtg tctgatcgcc acgagcaatt ttttcttgat taaatgcatc
    38701 tccagcctct ttgattagtt ctacttcttc taagacttgt tcatataagg aattttcagt
    38761 tagaggatga ttttcgggaa gcagtccatc ttcatccaat tctactaatc gttcatcctg
    38821 ataattttcc ggacgataaa actctacacg attatggtag atatcataaa gaccttctag
    38881 ccctttaccc ataccgattg gccaattcat cggataagat tcgatatcta atagctcttc
    38941 taattcttct aacaattcca atggttcacg accatcacga tctagtttgt tgataaaagt
    39001 aaatatcggg atgccacgtt tttttacaac ttggaataat ttctttgtct gtgcttcgat
    39061 cccttttgca ctatcgatta ccatgaccgc actatccacg gccatcaaag tacgataagt
    39121 atcttcagaa aaatcttcat gtcctggtgt atccaagata tttactcgtt tcccttgata
    39181 atcaaactgc ataacagaac tagtaacaga aatcccacgt tgtttctcga tttccatcca
    39241 gtctgatttg gcaaaattac ctgttttttt gccttttacg gtcccggctt gacggatagc
    39301 cccaccaaac aatagtaatt gttctgtaat cgttgttttc ccagcatccg gatgggaaat
    39361 gatcgcaaaa gttctgcgat tgtccacttg ttgctttaat tttggattat tcataaccta
    39421 actccatttc ttccattcaa ttatttatat tttctctagg cacagattgt ccgatctctt
    39481 aaagaaagac aatttcatat agggctgtga caaaagccgt gtagcagtct ctttttccga
    39541 gtaaacggcg ttctagagac agcctatcag caataagccc acccaagcca aaaatacgaa
    39601 aagctgtttt tgcttggctg ctcttattac ttaatgcagg atagcttttt cacaaccttt
    39661 gtcaactact acaactgaat cagtatagca tggattcagc gaatgaaaaa gccaccaaac
    39721 cataagagtc aaatattttt ttgtcagctg actaaaagaa aagacgtgtt gcttgtttat
    39781 tcaagcaaca cgtctttcat aaccaagttt ccaattatct tcttggctcg tcatcttcga
    39841 attcttttct gaagtatctt cgttcttctt caggttccgc ttctgtttct tccggatcat
    39901 gaaaaatgac acggatttta aggattcgag aaccttccat ttcttcagaa accagcgtaa
    39961 tattatcgac atcaaacgat aacttttcgc cttcatccgg aatcatgcct aatgctgtaa
    40021 tcaaataacc agccatcgta tctacatcac tcatatgcag atcactgtca aaagcttcat
    40081 tgaactcatc aatcagcata cgtccttgga tgatatattc gtgttcatcg attttttcat
    40141 aaagattctc aacttcatct gattcatcat cgatttctcc gacgatttct tctaaaaggt
    40201 cttctagtgt tgctaaccca acgacgccgc catattcatc taataaaata gccatctgat
    40261 tctgcgtctt tttcatttca tataacagat catcaataaa gaccgtttca ggaacgaata
    40321 aaggctcctg catgattttc ttgatatcta aattatcaaa gccgaattta tgggcagctt
    40381 ttagtaaatt ctttgtatga aggattccga ctactttatc tttgtcttcg ttataaacag
    40441 ggattcttga atagttttcg gataaaactt cattcacatt ttcttccaca gtgtcgttga
    40501 tatcaatcat aaatgcatcc gttcgtggga ccatgacttc tcgggcaact ttcgtatcaa
    40561 gagaaaaaac cccttggagc atttctaatt cttcattatt caatacgcct tcgttttcaa
    40621 gcatataacg catttcatct ctggtcattt ttgaatcttc atcatcaaaa gtcatcggcg
    40681 tgatacgcgc caataaactt gtggaagcag aaagcagcca gacgaagggc ttagctacta
    40741 caccaatcaa gcgtatcagc cctgaagtga actttgcgac ttcttctgat ttatttaaag
    40801 caatacgttt agggtacaat tctccaaaaa caatcgatac ataggtcaaa atagccagca
    40861 caatgatatt tgcaatattt tttgccgctg tgccgccacc taataccgga gctaaccgtt
    40921 ccgataaagt attagctagt gaagcaccag acaaaatgtt gaccaaagtg attcctactt
    40981 ggattgtcga taggaaatta tttggattct gcaatatttt taaaagcttt tgagatttca
    41041 catctccttc atcagctttt tgctcgattc gattcttatt gatcgaaaca acagcaattt
    41101 cggaagctgc taaaaaagca ttgatcaatg tcaaaacgat caataataaa atctgcgcta
    41161 acagcgactg actctcaggg tcagcattca taatcgcatt ctctccttat aaaattaatt
    41221 tttagtttac gatagaaaaa aacgtggcac tatagccacg ttaaaatggt atcacaaagc
    41281 aattttcttt gcaataaaaa caagtgtact aaaactacct acgaggtcgt agcaattttc
    41341 ttcttgtttt cattttgctt gtcttctttg acgattttga ttatatagga aatgatcgtc
    41401 ttgcagattg cgtaaaaagg aacacctaag aagataccaa gcaatccggc aatatttcca
    41461 gctactagaa gaacgataat gatcgttaat ggatggattt tcagtgattt cccaattaca
    41521 ttaggataaa tgatattccc atccaactgt tggacgatta gcacaaccac acaacaaagt
    41581 aatgctttta ccggatcatt gaagactgtt actagaaatg caggtgctag tcctagataa
    41641 ggtcctaaat atggaattag gtttgtcaat cccgcaatga ccccaaataa gaaagcataa
    41701 tccacaccaa ttaccatata tcctaaaaat gtgaaggtac caacgaataa acattcgatt
    41761 gcttgtccgc taatgtaatt agccaatgtt ttattcagtt gccccaataa ctccacaatt
    41821 tggtttcttc ttttttctgg gaaaaactgt tggatgtttg gcactagttt ttctccgtct
    41881 ttcaacatat agaacaagat gaatggtgct gtaatgatta ctacggttgc cgaagcgatc
    41941 gttccaacga tcgaacctaa actattggat actccactaa ggaattgctg aatgattgtc
    42001 ccgtaagaaa tgtctaattg ctcaaaatat ttattgatat ctacttcctt gaacaaaggc
    42061 aattcggcta cctcttttaa ccagctttct acctgtttga tgaaatcagg catattagat
    42121 gccaatgagg aaatttgctg tactagactt gggatgacac taagtaaaat ccaaataatt
    42181 gctgcaacta aaaggagcag cacaattgcg acagcccata ttcttttgat ttttgctttc
    42241 atcaacagct tgacaatagg attcaataaa tagtaaagaa agcctgcaat cagtacaggt
    42301 gcaaataacg tggaaaaaaa tgtcccgatc ggttcgaaaa taaagtttat ttctgatgaa
    42361 atcatgatca atgcagctat gatcaataat tcaagcgacc aaaacattag tttagactgt
    42421 ctaagttttt caaacaatag atttcctcct ttctttctta ctagtatata ttatattcgt
    42481 taaaaattct tttattcttt ttttattttt gaaaacttgc catacttttt atttgtttta
    42541 ttttccagta tactatacga aaggaaggtg gctagaccat gaaagttgta caaacaaaag
    42601 atacaatgag caatatttac ttagatgctg tacggatcag gcatcaagtt tttgtagtcg
    42661 aacagggtgt gcctttgtct cgagaaatag acaaagatga agcccattgt atccacttcg
    42721 tcctgtactc agataaaaaa gaaccgcaag gaactgtacg tcttttgcct ttagaaaacg
    42781 gaaaaatgaa attacagcgg atggcgattc tttctgaata cagacaccaa gggttaggaa
    42841 aaatattgat tgaagaagca gaaaactttg ctaagaatca aggctataat acgattttat
    42901 taggggcaca gtccacagct gaaacttttt acgaaaaact aggatataca gcttacggcg
    42961 atccttttga agatgctggc atgcctcata tttatatgaa aaagacttta taaaaattta
    43021 tttcgaaaaa agcaaaaaac agcaagcttt tgagaaaaat ctctcactgg cttactgttc
    43081 ttttttgtgt ttacttacgc gacaattgct tgtaacggtt ataccaaata tcaatatagc
    43141 cttccgagaa cgggccatct ccattattga tccagtcaac cagaatcttc acattttctt
    43201 ttaggatgaa gtcaatatcg ttcgggtaat tcatcatttt gctgtgcatc tcatattcat
    43261 cgacatccaa tagtcgtttc tcgccgtcag gaaatacctt gatatccaag tcatagtcga
    43321 tatatttcaa ggcctcatcg tccagcaaaa aaggtgaagc tagattacaa taataggaaa
    43381 cccccttttc tctgatcatt gctattacat tgaaccagta ttttttatga aaataaacaa
    43441 tcgctggttc gcgcgttacc catcggcgtc catcagattc agtgactaat gtgtgatcat
    43501 tcacgccgat catagagtgt tcgcttgttt ttaataccat ggtatctcgc cacgttcgat
    43561 gcaatttgcc gtcgtgcttg taactttgga tcgtcacaaa ctctccttct tttggaactc
    43621 ccatagcaac ccttccttaa gcagcatttt gtgctttgtg tttgggtgtt cattacaccg
    43681 acatcataat tattatatca ataaaaatga gctttgccta gaaaggattc ctattgtttc
    43741 gatttttctc taactgatct accagtttca tttggacctt aggaaaaacg accgaatcaa
    43801 atgcatcagg cttcaaccac ttcgaagttt tgttctcggt aaattcttgt tctgctccct
    43861 cggttgcccg tccgtaaaaa aggagaacat gccatttcag atgactaaaa atatgagtaa
    43921 cttctcctaa atgtcgtgtc tgccaaacaa agagttcctg cttttcaaat gggagatttt
    43981 gctcttcttc tgctactagg tcatcaaaca gatcgatttc tggctttgtt tcccattctt
    44041 ttttcaatcg ctcatactcc tcttgtgtca cttccatcat tggaaatgtc cacatattcg
    44101 ccagcaattt ttggctatct ctttcttcaa aataatacgc tccagaatga ttttgaagag
    44161 ctgcactgat ataataaacg tcttttggct ttgctttttt tgtttttaca ggaaaactcg
    44221 tttggattcc tcgtttgtta gctaaacaaa aggcttggat cggacaagtc tcacactttg
    44281 gagaagttgg tgtacagata gctgaaccta gatccatcat tgcttggttg aattcacctg
    44341 gatgcttttc atcaatgatt ttccgcatcg cttcatcaaa gattttcctg ctagaagctt
    44401 ttgcgatgtc tgcttcaatg caaaacaatc tgctgactac tcgcatcacg ttgccgtcaa
    44461 ctgcaggttc tggaagtcca aatgcgatac ttgcaatcgc gcctgtcgta tatggtccta
    44521 ttcccttcaa tgagctaatt tcttcaggcg tttgcggcat ttccccatca aattctgaca
    44581 tgatctgttt agcagcagct tggatgttcc gggctcttga gtaataacca aggccctccc
    44641 atgcttttaa aagcttttct tctggagcat ttgctagctc ttcaattgta ggaaaccatt
    44701 ccatgaaacg ataaaaataa tcgatcactg tgtctactct ggtttgctga agcatgatct
    44761 cagagatcca gatacgataa ggatcacgat tatagcgcca aggcaggttt cttttttctt
    44821 gttcatacca ttgaatgaac tgatcttgaa attcttttgt ttctttatct gtccattttt
    44881 cccattcttt attcactttc ctcttccttt tccgtaatga atcgctggat catatccaaa
    44941 tcaaatcctt tttgatataa gctttgcttt acttttagat ttcttttttt aggttcaaac
    45001 cttaaatttc ttcgccatag tttatctcct tgtttgacta aataatcata ttctatttct
    45061 tgatctgctt cttgcggaag atcagctatc gcttgttgga tcacttcttg agaaaagcct
    45121 ttcgtcatca atgtttgttg gatttttctc aataattctt tttggctttt tccgtgattt
    45181 tttccaaacg ctttttcggc tgtctgatgt gcattttgaa cttggtcttc aaatgtatat
    45241 tggctgagcg cttgttcaat gatttcaggt ttcaaacctt tttgctgcat ctgctgcgct
    45301 aatttctttg gtcctttgtc acttaagcgc atattcgtgc gcacataact ttccccatag
    45361 accaaatcat cgacaaggtc caattctttt aagcgggcta cgattttatt tcgatcttct
    45421 tgaaggattt ccttttcttt taagtatgtt cggatttctt tttccgatcg caactgataa
    45481 cttaagtaat tcattgctag gtgaaaaccg aaatcagctc cgctactctt cttgatctct
    45541 tggatagttt cttcgtctaa ttcccgtcct tttaataatc gatagcgtac taatacatct
    45601 tcagatactt gtaaagcttc tccttcagat aaatctacgc gatagaaagg gcctttgcct
    45661 ttactgattc tcgtaacggt taacataaac atcctcctcg aacatatatt ctctatcata
    45721 ccacagaaaa tccccgtaat caggtattat atgttagaat aaaccacaga aaaaagaaaa
    45781 agggagatac ttatggcaga aacaattgtc aaaactggac aaacggttcc tttgaaaatc
    45841 aagcgtttag gcataaatgg tgaaggaatc ggttatttca aacggttgat catatttgtt
    45901 ccatatgcac taccaaaaga agaagtacta gtgaaaatca cgaaagcaac tcctcgctat
    45961 gcagaaggag aattaataaa agtcaaaaaa acaagcaaag atcgcgtagt ggcaccatgt
    46021 cctgtttact atgaatgcgg tggctgtcaa ttacaacact tagcttatca agctcaattg
    46081 gattttaaaa aggatctgct tttgcaagca ttggaaaaat tcaaaccagc aggctttcga
    46141 tcttatcaac ttttgccgac gatcgggatg gatgagcctt ggcattatag aaacaaagca
    46201 caatttcagt tacgaaaaaa taagcagact caaaaaattg aagctggttt atacgaagca
    46261 aactctcatc agttagtccc tataacagac tgcttggttc aagaacctcg aacacaaaaa
    46321 gtaatgaata ctgttgttca actattgaat aaatttgatg cacccatcta tgatgaacgg
    46381 acaaacagtg gaatcttccg cacaatcatg gttagaatcg gtgttaaaac tggggagtta
    46441 caagttgttt ttattactcg cagtaaaaaa ttcccgcaaa aaaacgcaat gatccgtgag
    46501 atcaatgaac gactgcccga agttgtttca atcatgcaaa atgtccaggc acaaaaaacg
    46561 tctctcgtga tgggggatga aacgatccac ttatggggaa aagaagccat tgaagaacaa
    46621 atcaatgaag tgactttcga tctttctcct cgtgccttct ttcaactcaa tcctcagcag
    46681 accgaattgc tttatggcga aggaatcaaa gcattagatg tccagcctaa tgaaacgatc
    46741 gtggatgctt attgcggagt tgggacgatc ggcttaagtg tagcaaaaca agccaaagaa
    46801 gtacggggaa tggataccgt tcctcaagca atcgctgatg caaaaaaaaa tgcggaaaga
    46861 ttaggatatc acaacactcg atatgaagtc gggacagcag agcaagttct gcctaaatgg
    46921 ttgaatgaag gttttcagcc tgatggtatc atcgtagatc caccacgtac gggtttggat
    46981 aacgcattga tccaatcatt attgaaatac cctccaaaaa aacttgttta tatctcctgt
    47041 aatgtttcta cacttgccag agatctggtt aatttaagta aaaagttcaa gattgaatat
    47101 ttacagtccg tcgacatgtt tcctcagact gcacgttgtg aagttgtcgt gaagatgacg
    47161 agactcgctg actaaatgaa agaggttgtg aaaaagtctg ccctgtatca agtaataaga
    47221 acagccaaac aaaaatagct cttcatgttt tatgaatact gtacttgtga ccgaagagtt
    47281 aacaggagga cactatttat ttaaaaaaag ggttgtgaca tagtttttgt cacagccctt
    47341 tttgattatt attggatatt cacgtctatc acttgataaa atgcatttgt cgtatcgctg
    47401 atattccata ctgctaaaat cacattatat ccttttcgat cctgcggaag tgtgatcgtt
    47461 tggttgactg tttttggtgg aacagttgct ttgtcgtcta tttttgtgat caattcaaaa
    47521 tcactaaatt tcaaaggttg attaggattc caagttggtt tggtaatgta gtaatcccaa
    47581 gtacttgtcc gatgttgtgc tgttaaattc caagtaatat ttaatgttcc tggattaacc
    47641 atgtttttat gccatctgtt agatgtctgt tcatctaaag gctcaaagcc gctgactcct
    47701 gcactagcaa tttttccatc aatgaatgta tttttggtag cttcgatact ttgcggttcc
    47761 cattgtgctc ttccgacatt ttgatttaag tttcctgctg ctgatgttcc taggtatgca
    47821 cggcttcctg gagaagtaat ataaccatgc gcaaaacctg gaatgctaaa accgaacaac
    47881 cctaaactaa ctaacccaat aaacaataac gtactaatct ttttcatgta gaaacctcct
    47941 tcatttgata accacattgt aaacgcttta ttgtattaac acaaacatta tgcttttata
    48001 attttatgtt gaagtaaaaa aggtgaaaaa agtaagatgc agattataac agaagtagac
    48061 gagaaaagta caaatagaaa acatgagaat caaatcatat gatctttttc aaaaacatca
    48121 ttcatataaa caaatgttca actttttaat aacaacaatt atcaattttt ttcttacttc
    48181 acaaactaaa tacaggtctt gctgtgagcc ttcatggtaa actaatatta tagaaaggag
    48241 ttagtaaaat gaagatgata aaagatattc gtttttgggt ttgtgttata ggaattgtca
    48301 tattaggctt tttatcaggg ttgcttagcg gaaatcccgg aaaatattac tattctttgc
    48361 aacttccacc atttgcacca cctagctgga tatttgggcc gatgtggacc ttactgtata
    48421 tattgatggg tatttctctt tatttgttac ttaatcacaa caacaaaaaa cagcgaaaca
    48481 atcttgtcgg tctttttgtg attcagttca tttttaattt tatatggtct gctctatttt
    48541 ttaatttaag aaatattttc attgcagcaa tcgatattac acttttagtt attttcttgt
    48601 cagtgcttat gtatcagttg tggctgcatc atcgcctggc aatgtggctc atgattcctt
    48661 attatttatg ggtactattc gcaactctat tgaattattc aatttatttt ttaaactaag
    48721 cgctaaaaag agacgtcctg taatttaaca catagaaaaa gtgccaccta agttagattt
    48781 tttgtctaat ttaggtggca ctctttatta accaaactat ttttttctag tacccacttg
    48841 ttgttccata ctcattattc tggtcataac cataaccatt ttgttcctgt ccagcgtaag
    48901 gatcataact ttgagtatct tgacttggtg tatagtactg acttgtatct tctgtttgct
    48961 gataataggt attcggatct tggtactgat catatgtgtt ttctgaatag gaagaataat
    49021 cggtgtaccc ttcactattc gatccatcac cgtttgtcga atcgccatct tccgaatcat
    49081 caaagaacat cattgaagca ttctcatttt tcaaattagg taatgtatcg cttgttttta
    49141 tatttaattg tttcttcagt tcattttgga tcgaaagaag atcatttttt cctaaaattt
    49201 gatagtagat atcattgatc atttgtcctt cgccttgcaa ctggtcttgt ttgattgttt
    49261 caaacgccgg ggtgtagttc gtcgctacat caagcatgtc atcccaatct aagtccgtcg
    49321 tcacattgtt ctcaactgct tttaaaattt ttctataatt gcttacgcca tctaaactta
    49381 aaactttatt gacgattttc gtcactactt cccgctgacg acgttgtcga ccgatatcgc
    49441 cttctggatc ttcgtgtcgc attcgagaat aggctaaacc tttttctcca ttcaatgttt
    49501 gttcacctac tggtacatgg acaccatcca aagtaaagtc aattttatta ttcactttga
    49561 tgccaccgac cgcattgatc aaatcttcca tgccatccaa attgatcgtt acataatgat
    49621 caataggaat atcgagcagt tgctcaattg aatccatggc catttcgaca ccaccaaatg
    49681 cgtaggcatg atttaattta tctaccgttc cataacctac gatattcgta taaatatctc
    49741 ggtccaaact gatgatcgtt gatttttttt gtttcggatt aactgttact accatcatcg
    49801 tatcagaacg tccttgttcc gttcttccta atccaccggt atctaaacct aatagcaaaa
    49861 ccgaaaaagg ttctttgtca tcaatgctta ctctctcaga acgtttggag gatattcgat
    49921 tagagttttt agaaattttg tttactgttt ggctcgcttc tcccataaat ctgattccgt
    49981 atgctgataa tccggcaatc agcaaaacga atacccctaa caaggttaat agaacttttt
    50041 gccatcgctt cataatacac ctctgtttca cattttctaa aatattgtct catataactg
    50101 ttcaatcagc aaattcactt tttaatcata agaaaacttt aaaaaacatt tttgtgtaac
    50161 gattattatt ttttaaaatt tctcaaaatt cttaactatc ataccatacc gtgaaaaaga
    50221 tcgaaagacc gaatacacgc agttcgcaat cgttttatct ttttttatgt attttttcca
    50281 gaaaaagcga acaacaaggt attttccaaa taatcgtgca gtaaaatgat cgcacatacc
    50341 tttcccatct ttttaacagt ctttgcctac cgttcagatt atcattcgat ttcacgacaa
    50401 tttcttccta tgactggtcc ttttgttaaa cccatcttct attcgtttta tttccagctc
    50461 actgcatggc tcttaaaatg actcgaacta gtgattgcat taccatcatc ttttaatgga
    50521 tagatatgct cctcttcaaa gtaaaacgat tttcttttaa agtaatagaa ttgacatggt
    50581 aatgagtatg tatactagtg gtttcacaaa tggtctttta ttcaacatcc aaaaactgaa
    50641 atttctttaa aatccattac taacgaagaa aatgttcctt gcttgataat tagttaggac
    50701 atgtcaagtg aacaaatgca tttacttagc caaaaaa
//
LOCUS       DAFEML010000016        47468 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFEML010000016
VERSION     DAFEML010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.016"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(53..787)
                     /locus_tag="LP468_001040"
     CDS             complement(53..787)
                     /locus_tag="LP468_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2080593.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="LP468_001041"
     CDS             1114..1524
                     /locus_tag="LP468_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL2080594.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="LP468_001042"
     CDS             1517..2218
                     /locus_tag="LP468_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL2080595.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="LP468_001043"
     CDS             2218..3804
                     /locus_tag="LP468_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080596.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="LP468_001044"
     CDS             3823..4044
                     /locus_tag="LP468_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL2080597.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="LP468_001045"
     CDS             4041..4802
                     /locus_tag="LP468_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL2080598.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="LP468_001046"
     CDS             5182..5691
                     /locus_tag="LP468_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2080599.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="LP468_001047"
     CDS             complement(5766..6305)
                     /locus_tag="LP468_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL2080600.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP468_001048"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP468_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL2080601.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="LP468_001049"
     CDS             7318..8169
                     /locus_tag="LP468_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL2080602.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="LP468_001050"
     CDS             8197..8832
                     /locus_tag="LP468_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL2080603.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="LP468_001051"
     CDS             8852..9625
                     /locus_tag="LP468_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2080604.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="LP468_001052"
     CDS             10033..10830
                     /locus_tag="LP468_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL2080605.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="LP468_001053"
     CDS             10808..11221
                     /locus_tag="LP468_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2080606.1"
                     /translation="MIDRSWSRKRGSFLQKEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="LP468_001054"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="LP468_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2080607.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="LP468_001055"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="LP468_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL2080608.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="LP468_001056"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="LP468_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL2080609.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP468_001057"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP468_001057"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL2080610.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="LP468_001058"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="LP468_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL2080611.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="LP468_001059"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="LP468_001059"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL2080612.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="LP468_001060"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="LP468_001060"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL2080613.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="LP468_001061"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="LP468_001061"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL2080614.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="LP468_001062"
     CDS             21905..22483
                     /locus_tag="LP468_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2080615.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="LP468_001063"
     CDS             22535..23017
                     /locus_tag="LP468_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL2080616.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="LP468_001064"
     CDS             23134..23508
                     /locus_tag="LP468_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080617.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="LP468_001065"
     CDS             complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="LP468_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2080618.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25685..26275
                     /locus_tag="LP468_001066"
     CDS             25685..26275
                     /locus_tag="LP468_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2080619.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26403..27752)
                     /locus_tag="LP468_001067"
     CDS             complement(26403..27752)
                     /locus_tag="LP468_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080620.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27920..28660)
                     /locus_tag="LP468_001068"
     CDS             complement(27920..28660)
                     /locus_tag="LP468_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2080621.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28673..30265)
                     /locus_tag="LP468_001069"
     CDS             complement(28673..30265)
                     /locus_tag="LP468_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2080622.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30833..31129)
                     /locus_tag="LP468_001070"
     CDS             complement(30833..31129)
                     /locus_tag="LP468_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080623.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31305..32030
                     /locus_tag="LP468_001071"
     CDS             31305..32030
                     /locus_tag="LP468_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL2080624.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32023..32865
                     /locus_tag="LP468_001072"
     CDS             32023..32865
                     /locus_tag="LP468_001072"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL2080625.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32868..33389
                     /locus_tag="LP468_001073"
     CDS             32868..33389
                     /locus_tag="LP468_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL2080626.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33642..34205)
                     /locus_tag="LP468_001074"
     CDS             complement(33642..34205)
                     /locus_tag="LP468_001074"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2080627.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34456..34725
                     /gene="rpsO"
                     /locus_tag="LP468_001075"
     CDS             34456..34725
                     /gene="rpsO"
                     /locus_tag="LP468_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL2080628.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34913..37039
                     /gene="pnp"
                     /locus_tag="LP468_001076"
     CDS             34913..37039
                     /gene="pnp"
                     /locus_tag="LP468_001076"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL2080629.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37549..37815
                     /locus_tag="LP468_001077"
     CDS             37549..37815
                     /locus_tag="LP468_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2080630.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37992..39950
                     /locus_tag="LP468_001078"
     CDS             37992..39950
                     /locus_tag="LP468_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL2080631.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40304..41605
                     /locus_tag="LP468_001079"
     CDS             40304..41605
                     /locus_tag="LP468_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2080632.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41735..43105)
                     /locus_tag="LP468_001080"
     CDS             complement(41735..43105)
                     /locus_tag="LP468_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL2080633.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43287..43610)
                     /locus_tag="LP468_001081"
     CDS             complement(43287..43610)
                     /locus_tag="LP468_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL2080634.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43935..44543)
                     /locus_tag="LP468_001082"
     CDS             complement(43935..44543)
                     /locus_tag="LP468_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL2080635.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44873..45589
                     /locus_tag="LP468_001083"
     CDS             44873..45589
                     /locus_tag="LP468_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL2080636.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45602..46297
                     /locus_tag="LP468_001084"
     CDS             45602..46297
                     /locus_tag="LP468_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL2080637.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46381..47010
                     /gene="udk"
                     /locus_tag="LP468_001085"
     CDS             46381..47010
                     /gene="udk"
                     /locus_tag="LP468_001085"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL2080638.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8787 c         9878 g        13412 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agaaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcacagcatg acagcattgg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ctagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt ttgcgaaaac tatttttata tcatatatat gtctaaaatc tatattataa
    23881 aagaaatgtt gtttgatcag cttctcttcg gtattagttc aaaacaaaac ggcaaagtat
    23941 atggagctac tttgccgttt tgtttctcta atactcaggt cagtttatag acgctcaata
    24001 aacggtgttc aaaagccagt ttctcggtat taagtcaaat ttatgcaaaa atgtgagaag
    24061 ccattttcaa aaaatatttc ttaatactcg aaactgagcg gctttttcac gacctctcaa
    24121 taaacagtgt tcaagagaca gcctatcggc aataaggctg aacgtctctt tcacaacctc
    24181 ttttatcaat ctgctacttc ttctttctta gcgaaactcc aaatcagtcc gataacaaaa
    24241 ccgataactg ctggtacgat ccaccccatc cccaatttga aaaacggcaa gtagctttcc
    24301 gcaacatata aaagattttg aacaataggt gtttgtttga tagtttctgg gcaagcgttc
    24361 aacccatcaa aaatcgaagc aatcaatgta aaataagtag tcattcgata aacagccgta
    24421 cgctgcttaa acaaaggacc aactaacact agtaaaatca gtgtcattgc taatggatag
    24481 atgaacatca aaacaggcaa cgaaaattga atgatattcg tcaagcctac gtttgccgct
    24541 aaacaaggaa ggatactagc aagtgcaaca aagaatgcgt aatttctttg cggaaacaaa
    24601 tctgtgaatg tttctgcaaa agctgtaatc aaaccaatac cggtcttcaa gcaagctaat
    24661 ataacgataa atgctaataa gatactgcca taagtaccta aataatgatc agcaatctga
    24721 gccagcgtga tcccgccatt ttcacttaga gcaaagctac ctaagctcat agcacctaaa
    24781 taagcgagca aagtataaat gattcccatc aatataatgc tgatcgcacc agatttgatc
    24841 gtgtctttag cgatttcagc aggttttgtt acacccatgt tttggattgt tgtgacaatg
    24901 atgatcccaa atgctaaagc agcaagcgca tctaatgtgt tatatccttg agtaaaccct
    24961 gtgaaaaaag catgctcttg ataatttggc tgaataggcg cttgatttac agaacctagt
    25021 ggattcaaaa aagcaaggag aagcaaagca cctaataaaa ccaaaaatgc aggattcagg
    25081 aactttccaa cataatctaa tatctttgtc ggttttcttg aaaaccacca agccagcaca
    25141 aaaaatacaa tactgaaaat tgctagatat agcgtctgtc tgctaggatc gataaatggt
    25201 gctaaaccaa tctcgaaaga tgtggttgca aggcgaggta aagcaaaaaa cggtccgata
    25261 actaagtaaa gcaagatggt aaaaaccatc gcatatgttt gatttatccg ttttgctaat
    25321 tcatatacac ctgagctttt cgatacacca atggcaatca cccctaagaa gggaagaccg
    25381 ataccggtaa ccaagaaacc tagattcgcc caaaaggtag cagcgcctgc ttcttgaccc
    25441 aaatgaacgg gaaagataag atttccagca ccaaaaaata gaccgaaaag catggagcct
    25501 ataaaaagat agtctttaaa tgataatttt tttgtcatac ataactcctt tacggttttt
    25561 ttaaaagtaa caaaatttcg aaaaatatgc aacaattttc agaaaatttc ctatataaaa
    25621 cgacggttat ttaataacgt aagtgataaa ataaaagcgc tgaatcatct gaggaggaat
    25681 catcgtgaca aagtcgagat tagaagcatt tactgatgga gtggtagcca ttgttttgag
    25741 agttcttgta ttagagatca agatccctaa tacatctagc tttcattctt tatgggtcat
    25801 ccgaaataca ttattagctt ataccatcag ctttatattt gttgcggtga tctgggtgaa
    25861 ccatcatcgt atatttcaga tggcagaacg aattaattac cgagtggtct ggtcgaatat
    25921 ctttttgctc ttttggctga ctttatgtcc ttctgttact agttgggtcg ggcgtaaccc
    25981 tgaagctttt tggcctgaga tggcttatgt cttagtatac acgatgtgga gtttttcttt
    26041 tggtatcttg atgaggcaaa tcatgaaagc aaataaacca gattcccatg tcgtgagagt
    26101 tttgtcaaag gaccgtcgaa gtcttatctc catgatgatt aacttatgct tgattgccgg
    26161 tgtctttttt gtaccgttga tcgggttatt cggacgtttt tttgtatctg gtatttggat
    26221 tttttcctat aaaaaagcag atgcctatta tcagcggttg tttccgggga aatagaaaag
    26281 aggctgggac agaagctttt aactccaaga aataagccga aatttcacaa aaatttaaga
    26341 agcaattttc gtaaattcct tcttatttct cgaagctgac cacttctgtc acaactactt
    26401 tcttacttct tacgttcata tttcatatga tagattagta atagaagcaa gaaccacaca
    26461 ggtgttagta ataaagcgat tctcgtatct tttcctagga acaagacgac acacacaaag
    26521 gccatgtaaa gaaataccag ataattacta aatgggtaca acggcatttt aaatgaatga
    26581 gcttttttgc cgaggatact tttacgatat ttcatgtgcg tgtagacaag catactccag
    26641 ataaacaaga aacaagtagt ggcaatactg cttactagtg tgaatacttc actaggcatc
    26701 acgtaattca agataacaga aatgaaaatg acgatagtag aaaatgtcaa agcattccct
    26761 ggcacatgat gtgttgttaa ctttttgaat tttttagggg cactgccttc ttgcgctaaa
    26821 gaacgaagca tacgtcctgt actatatatt gcactgttgc aggcagaagc tgctgcactt
    26881 aatacgacta aattgatcaa ggaagcagca atcgtgatcc caatttccga aaatacttct
    26941 acaaatggac tgttatctgg attcaagctg ttccatggat agattgccat aatgacaaaa
    27001 agagatccta agtaaaataa gatgatcctg ataggaatat tattgatagc ttccggcaac
    27061 actttttcag gattttctgt ttctccagcg actaatccaa ctaattctat cccagcaaaa
    27121 gcaaaggtta ccatttggaa agctaagata aatccttttg caccagttgg aaagaatccg
    27181 ccatgagacc atagattcgt gatactggct gtgccaatat ctgtcgtata gtgggtgagg
    27241 atcatataag ctcctacgag gataaaggca atgatcgcta caactttgat caatgcaaac
    27301 caaaactcta actcaccaaa caatgagaca gccaccatat tcaagcaaag aagaagacct
    27361 aatgcaatca gttcaggaag ccactgagga acaccaggcg cccagtagcg tacatacatt
    27421 ccgatggctg ttaaatcggc cattgcaatc gatacccagc agaaccaata cgtccagcca
    27481 gtgatgaaag ccgctttttt gccaagatat tctgcaacaa aatccagaaa agaatggtta
    27541 ttggtgtttg ataacagaag ttcgcctaac gcacgcataa tgaaaaaaca gatgcatcca
    27601 gtaataagat aggcgagcaa tatcgaaggg ccagctagct ggatagactt tccggaacct
    27661 aaaaacaacc ccgttccaat cgctccgcca atagaaatca gttggacatg tctatttttc
    27721 agtccacgct gcagttcttg ctcttcattc atttttaaat catcctaact aaaaaagttt
    27781 aattacttcc atattaaaag agttttctga aaaacacaac taagattcca aaattttcag
    27841 aaatttacct tttatgagta attcataaaa aagaactgcg gtaaacaccg cagctctttg
    27901 tcccaatcag ctattgatcc taagcattta aaatacgtga aaggaattct tttgtacgtt
    27961 cttctttcgg atggacaaag atatcttctg gtgtaccttc ttctgcaatc acacctttat
    28021 ccataaaaat gacacggtca gatacatctt ttgcaaattc catctcatgc gtcacgataa
    28081 gcattgtcaa gccagtatgt gctaagtctt tgatcgtatt aagcacttcg ccaaccattt
    28141 cagggtctaa cgccgaagta ggttcgtcga atagcaatac atctggattc attgataatg
    28201 cccgagcaat tgcgacacgc tgtttctgtc caccagataa ttgtgctggt ttggcttcga
    28261 tataacgatc cataccaact ttttccagat tttcgattgc tacttttttg gcagtttctt
    28321 tatctcgttt caggacagtt gtttgaccag acatacagtt ttccaagaca ttcatattgt
    28381 tgaacaggtt gaaggattgg aaaaccatac ctagattcgt tcgatattta ggtaaattat
    28441 atttaggagc taatacattt tctccattat aaatgatctc gccgcctgtt ggtttttcca
    28501 gtaaattgat acagcgcaag aaagtagatt taccagaacc ggaagaaccg atgatcgtca
    28561 caacttcacc tttattgact gttacgctga tatctttcaa tacttcattt tcaccgaagc
    28621 tttttcttag atgtttgatt tcaataattt tttcattcat gattcttcct ccttattcct
    28681 gcaaatttga attgtcgatt tcttcaagct tggtataagc tgaaggacca tcgattttct
    28741 tttctaccgc ccgcaggatt ctggtgatcg taaaggtcat gactaagtag atgatcccga
    28801 cgatcgtaaa tgtttggaag aattggaaat tcgcaccgga agcagagttt ccttggaaga
    28861 acaaatcagc tacgccgatt acacttaaaa ctgctgtatc tttgatattg ataacaaact
    28921 catttcctgt tgctggcaag atattccgta aaacttgtgg aataacaact tttctcatcg
    28981 tttggccatg ggtcatacca atggcttgcg cagcttcgaa ctgcccttca tctactgcaa
    29041 aaatcccccc acgaacgatc tctgtcatgt aagctccagt attgagagag acaataaaca
    29101 aagcggcaat cgttcggttc aatgaaatgc caaaagcgag tgccagaccg tagaagatga
    29161 ccattgcttg taccatcatc ggtgttccgc ggaatacttc gacatagata gaaagaagtg
    29221 catttccgat tttttggaag aagcgagtca gtgcatttcc tgattcaggt accgaacgga
    29281 agacaccaat cagtaatcca agtgtagtac cgacaactgt cccgatcaat gcgatgaaca
    29341 aggtaagtcc agcacctcgt aagaacatat tgccgtattg tttccaaatc gtagtgaaat
    29401 cagaaatgat gccaggtttt tcttcactat cagttgcagc aggctgatct ttgactgctt
    29461 ggtccataat tttggttcgt tcatcgttag agatgccaga aagaatctgg tttacttttt
    29521 ggatatccgg gtcgccttta cgcataccaa cagaaatctg aacatcttcc gggtttgtct
    29581 ggaagccatc tgcaccgctg aattcaagca tttccaagtc tttgttcaca ctagttgccg
    29641 ttacaccttc cggacgttcg ctgacataac catcgatcat tccagaagct aaagctgttc
    29701 tcattgctga gaaattatcc attgcttgtt gtttctgcac atctggtatc tgatcgatca
    29761 cagtatagtg gaatgtattt aactgagcag taatctttgc tccagaaaga tctgctaaac
    29821 tttttgcttt tgcatatttg ctatcttttt gaactactac tactaattgt gattcgtaat
    29881 aaggatcggt aaaatcaatt tcttttcgtc gttcagcagt agggctcatt ccggcgatga
    29941 tcgcgtcgat cttgcctgat tgaagggcag gagccagacc atcccatttc gtttggacga
    30001 tgactaattt tttccctaaa ccatctgcta cttttttagc gatttgaaca tcataaccgc
    30061 cggcgtaact attttggcct tgaattggca aggcattatt ctcatctgtt tgttgagacc
    30121 agttgaaggg tgcataccca gcctccatac ctacgcgaaa ctcatcgctc ggtgtttttt
    30181 catctgcatt tgccagagat cccacactga atagtgagaa gacaaaagca aatagtacgg
    30241 caactgaaac catatttttt ttcatttttt tctccctttc tgattatatg atacacgagc
    30301 ggtctagatg aaatgcggta aagctttatc tgaaaaaata aaaagcgacc gatttataga
    30361 tataaaaagg ccgctaaaat tccataaggt gataaacctc tcacaaaaca tagcgcaact
    30421 tagcatcact gctaagacag tccgcaagct cttaacttgc gtcccaacat acactccaag
    30481 caaaaaagtg cacatttcgg cgatcctccc tattcctgct tctccatgtt tgcttcactc
    30541 cacagggtta atgattctcg cgacctctac ctcattgatt gaggcatctc gtattcagtt
    30601 atttatacaa aaaaagttta cgatactcga gaggctttgt caatctataa ctgctgtttt
    30661 ttgaaaaaat actgataaat atagaaatct ttacttttac cgaaaaaaca atcaaaatgt
    30721 gaatcatcta tccattgcaa acgatagtat aattatacac aaaaatgtat gtaatacaat
    30781 aaaaaaagaa ctagaacaga aaatttcctg tgtccagttc catctcgatc atttaagctg
    30841 ccgctttctt tggctcacgt cctaggatcg cttgcaaaag aacaacgacg ccataaatgg
    30901 ctaatattag ataaatcaaa cttgagtatt gggtgattcc ccagccccat gttcgatata
    30961 cggctaatgt aatggctaaa acaattgcgg caatcacgtt gaataaagca aaagcccaaa
    31021 gatttccatt ttctttgcgt acaagataaa aaacagagaa ataaacgctt aacgctaacc
    31081 aggcgataca agccagaata acgccccaat aaataaagaa tggtaacata tcgattcacc
    31141 tcacttttat acagcagtat tgtaacacgt tttcattctt ttgtcagtga acattgtgat
    31201 aaattgttca aatgcccata acactttttt attcccattt ttctgacttt tcaacaataa
    31261 atttgttcga gtatgggcta taatggaaag tgaggtgaca aaacatgaaa caattaacag
    31321 tagacgaagc agcaaaagag atattagctt atcagcaaat tacatttttg accggtgcag
    31381 gggtatccac accttctgga gtgccagact atcgatcttt gtcaggaatc taccacggga
    31441 tggagcagcc ggaatacttg ctgagtcatc aagcaatggt gaatgaaccg gataaattct
    31501 atcaatttgt caaaaagatt tatcatcctg aagcaaaacc caatatcatt catttggaaa
    31561 tggcacatct agcgaaagaa aaaaatgttt gggttgtttc ccaaaacatc gacggtttgc
    31621 acgcaaaggc taaaagcccg caactcgtca attttcatgg aagtttgtat caatgtcatt
    31681 gtcgaaaatg tcaacaaacg gtagactgga aagaatatct tcacagcgac aaacatcaag
    31741 catgcggagg acaaatacgc ccagacatcg tgttatatgg tgaagggttt caagatggag
    31801 tcatggagca ggcggcttat gccgtcagcc aagcagagct gatcgtcatt gttggaacga
    31861 gttttcaagt tcatccgttt tgtgatctgg tacagtttcg ccagccgtca gccaaaatct
    31921 tagtaatcaa tcaaacgcct gtttatttag cggagcctta tacgtttatt caagaagacg
    31981 gagcggttgt tttcaaaaaa atacaagaat taggagcaga ttatgactga attcaaaacc
    32041 gaaaaagaaa aaatgattgc aggcgagctt tattttgcca atgatcctga gctggttgcc
    32101 gaccgtatgt ttgcaagaag tcaaagccaa atcatcaacc aagcagaatc agcggaactg
    32161 cgatcccaat tgttgaaaga gacttttggc cgtacaggga aaaaaatcta tatggagcca
    32221 gttatcaatt ttgattacgg atataatata tttgttgggg agaattttta tgcaaatttc
    32281 aattgtacat ttttagatgt cagcacgatt gaaatcggtg ataactgcat gttcgctccg
    32341 aatgtccagc tttacacggc gacgcatcca ctacatccag tgaaacgtaa cagcggtctg
    32401 gagtacgcaa aacccattaa aatcggtaat aatgtttggt taggcggagg agttatcgtc
    32461 acgccgggtg tcactctagg ggacaacgta gtagtcggcg caggttcggt tgtgaccaaa
    32521 tcttttcccg acaatgtagt gattgcagga aatcctgctc gtatcatcaa gacagtagag
    32581 gaagaactaa cagaagagtc tcttgaaaca ttacgtcata agatcgatat gatcgatcga
    32641 gagttgattg ctttattaga aaaaagaatg gatacggtaa ctaaaatagg acaagtgaaa
    32701 aaagaagaaa accaagcagt ttatgatgca aaaagagagc agcaagtatt ggataaagtt
    32761 gttagtctgc tgaaaaataa gggatataag gaaacaataa cagatacgta tgttgatttg
    32821 atgaaacact cgcgcgaata ccaaaacaaa atgaaggagg aataagtgtg atcgaaggag
    32881 agacacggcg aaaacaaatc atgcaaacct tggcaaatac agaaaaacca gtgagtgcta
    32941 gcaagtttgc gaaaactttt ggagtcagcc gtcagatcat tgtaggcgat attgctttac
    33001 tacgagctgc aggtaaaagt atcgtggcaa cagcaagagg ttatatcctc gaaacagaag
    33061 aaaccaatac tgggcacatc agtaaaatcg ctgtccagca tggaaaagat caaacagaag
    33121 aagaactgag actaatcgtt gaaaatggtg gtgaaatcat tgatgtaatt gtggaacatc
    33181 ccctttacgg tgagttagca ggaactttgc acatcaaaac gccacaagat atcgattcct
    33241 ttatgagacg ttatcaaaaa agtaatgcta ctttgttatc cgaattaaca ggcggcatcc
    33301 atctgcatac gatccgctac ccagaaaagc atatgctgaa aaacatcaaa caaaaactag
    33361 ctgaagcagg aatcctctac gaaggataac atcgtagctg ctacttttta tcctagaaac
    33421 tattctatca tctctgagat aaacacccat atggaagaaa taagaaaaaa taagaaaaga
    33481 tgcgtatcca atacacagaa ttttttggaa ttgcgatttc tagatgtcta tctaaatttc
    33541 gattagtgga gaaacataaa aaagggaagt gcagcttttg agcactcccc ttttttataa
    33601 agctttcttg tagcatagta tcgaaggaac ctgccaattc tctactcgat caccaatacg
    33661 ccttctttta gtgcaaatgg attttgatcg ttgatgtggt catagaacat cacaccgttg
    33721 atatggtcga tttcatgttg aacgacgatc gattcataat tcttcaaacg aatcttgtgt
    33781 ttttcaccat tcatatcata ataagacaca gtgattttgg catggcgaac aacatatcct
    33841 ggtacttctc gatcaacaga taaacagcct tcaccttccc ctaaacaagc atcttgaaca
    33901 gaatggctca aaattttagg attatacata acagtactta gagaaggtcc atctgcctct
    33961 gggtcaggac ttggtacgtg aacagcaatg attcttttag aaatatctaa ttgaggagca
    34021 gctaagccaa caccgcctcg taagtgtagt tcttcagctt tgattggatc ttggctgttt
    34081 tttaagaact caagcatctc ttttcctaaa gagatatctt cttcgcttaa tggaagagaa
    34141 acttcttttg caacttcgcg taaggtcgga tttccttcac gaatgatatc atccattgta
    34201 atcatggaat atgtacccct ttcttaaaag actgtgtttc aagtctattt tcgcattata
    34261 gtttaccaca aaaatggaaa agtagtagta agattgtttg aaaactacct tttcttaatg
    34321 attaactact tgattttcaa cccggtttca ggtaaagtat agctgtgtgc tctaggcaca
    34381 tgacctgcca cttggttaag cgaatcacca acgttttact cagtcgcagg ggaataatcg
    34441 aaagaggtga aagaaatggc aatttcaaaa gaacgcaaga atgaaatcat caacgaatac
    34501 gctcgccatg aaggggatac tggttctcca gaagtacaaa tcgctgtatt aactgaagaa
    34561 atcaaccact tgaatgaaca tgcacgcgtg cacaaaaaag accatcattc ataccgcggc
    34621 ctaatgaaaa aagttggtca ccgccgtaac ttgttagctt acttacgtaa aactgacgtt
    34681 caacgttacc gcgaattgat caaacgttta ggcttgcgtc gttaatttta gtcaaaaaga
    34741 gtgggattca catgaatctc acttttttta ctcgtatatc aattaagtaa aattccgtga
    34801 tcaagctaga tggactccta ctaaccaaat gaaagctgct caaaagacgg ctttcggcag
    34861 ttttcatttg tttagtagcg tcttgctttc acgagaagga aaaggagaag ttatgtcaga
    34921 aaaacaagta ttcaaaacga catggggcgg ccgtccctta caaatcgaag tcggtcagct
    34981 agcaaaacaa gcaaacggag ccgttttagt ccgttatgga gatacagtag tcttaagtgc
    35041 agctgtggcc tctaaagaag caaaagatac agactttttc ccattaacga tcaattatga
    35101 agaaaaaatg tatgcagcag ggaaaatccc tggaggtttc atcaaacgag aaggccgtcc
    35161 aagtacggaa gcaacattga ctgcccgttt gatcgaccgt ccaattcgcc cgatgtttgc
    35221 agaaggcttc cgtaatgaag tccaagtaac gaacatcgtg atgagtgtag aaacagactg
    35281 ctcgccagct atggcagcaa tgctaggttc ttctttagca ctatcaatct cagatatccc
    35341 atttgacggc ccaatcgcag gcgtagaagt tggtcgtgta aatggcgagt acgtcttgaa
    35401 tccaacagta gaacaagcag aacaaacaga tatcgaattg actgttgccg gaacgaaaca
    35461 agccatcaat atggttgaaa gcggcgcgaa agaagtttca gaagaagaca tgcttggtgc
    35521 attgctgttt ggttttgacg ctatcaaaga gttagttgct ttccaagaag aaatcgttca
    35581 agcagtaggg aaagaaaaaa tggaagtgac tttactgcaa gttgatgaag tattgaaaaa
    35641 agaaatcttt gatgcttctt acgctacaat gaaagcagca gtaatgactg aagaaaaact
    35701 tgctcgcgaa gataatatcg agcaggtgaa gatcgatatc cgcgaagctt atgctgagaa
    35761 atttgcaggt catgaagatg aagatcactt gttgaaagaa gttaaacaaa tcacagaaga
    35821 tcttgaaaaa gatgtcgtac gtgaattgat caccatcgat aagatccgtc ctgacgggcg
    35881 taaattggat gaaatccgtc cattgtcatc agaggtcagc ttattgccac gtgtacatgg
    35941 atcaggtttg ttcacacgag gacaaacaca agctttatca gcttgtacac tcgcacctct
    36001 aggagagcac caaatcattg atggtttagg ggtggaagtc agcaaacgat tcatccacca
    36061 ctacaatttc cctcaatttt ctgttggttc tacaggacgt gcaggctctc cagggcgtcg
    36121 ggaaatcgga catggcgcat taggtgaacg tgcgttagca caagtaatcc cttcagaaga
    36181 agaatttcct tatacgatcc gtttagtagc agaagtattg gaatcaaatg gttcttcttc
    36241 ccaagcaagt atctgtgctg gcacattagc attgatggat gcaggtgtac caatcaaagc
    36301 gccagtcgcc ggtattgcga tgggacttgt ttctgatggt gaaaactata cgatcctaac
    36361 tgatatccaa gggctggaag atcatcttgg cgatatggac tttaaagttg ccggtacaaa
    36421 agatggtatc actgctttac agatggatat caagattcaa ggaatcacag aacaaatcct
    36481 aactgaagca ttaactcaag caaaacaagc acgtatggaa atcttagaag aattgacttc
    36541 aacgattgct gctccacgtg aagaattaag ccaatatgca ccaaaaatcg aaatgatcca
    36601 gatcgaacct gctaaaatca aagatgttat cggtaaaggc ggcgatacga tcaacggaat
    36661 catcgatgaa actggtgtga aaatcgatat cgatcaagat ggaaaagtaa gtattgcttc
    36721 agctgatgca gaaatgatca aaaaagctat caagatcatc gaagatttga ccaaagaagt
    36781 caaagttggt gaagtttatc tagggaaagt tgtccgtatc gaaaaattcg gtgcattcgt
    36841 caacttgatc aaaggaaaag atggacttgt ccatatttcc caattagcaa acgatcgtgt
    36901 caataaagtc gaagatgttg ttaaactagg tgatgagatc cttgtgaaag taactgaaat
    36961 cgataaacaa ggacgcgtaa atctgtcaag aaaagcaatg ttgaacgaag atggttcaac
    37021 gaaaaatgaa gaaaaataat ttaattcata ggaataatgt acttgtgatc gtgaaggtga
    37081 cagggggaca ataattattc gaaaaaaggg gactgtgaca aaagccgtgt cacagtcctt
    37141 ttttttcgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc agccaagtta
    37201 aaaacattag gagctgtttt tatttggctg ttcttattac ttgatgcaga acagcttttt
    37261 tacaacctct ccaataaacg atgttcaatc agctgtccct cgatattagc tcaaaaaacg
    37321 gcaaaatatg aggaactatt tttccgtttg tttctctaat actcaggtca aaccgctgat
    37381 ttcacaacct ctgattcacg gtgttccaga agcagcttct acggaaataa gctgaacact
    37441 tttgttacaa cttctttttt tctggagttt cttggcgcat atttttggag tccttctgaa
    37501 taaagcgtaa aataaaagtg agaaatatgg ataaaggagg gaaaggagat gctgaatttt
    37561 ttatggtcgt tatttatcgg cggtatatta ggtttgatag ctggcgcaat tttaggaaag
    37621 gaagtcccgg gaggcgtatc tggaaatatc attatcggtt ttttaggtag ttggctcggc
    37681 gaatttttac taggaccact gggaccggaa ctcggcggtt tttatttgat accagcatta
    37741 ttgggtgcaa ttttttgcct tgctctttat tcatttgtgg caagacgtat cagagaacgt
    37801 ccaaagaaag aataatttta ttcaaataag ttgacacttc agtgtgttac ttggataatt
    37861 agaagcaatt taggaaagcg ggtgtcatgg ataagaatat catctatcat tcaagcttac
    37921 ctaaaggata tccatataac aagaaatgag ggaaaaacgt ggcaacaacg cacaatacca
    37981 aaaagatatc aatgactggc ctgcttgtag cgatgggagt cgtctacgga gacatcggga
    38041 caagtccgct ttacgttatg aaatcgattg ttgaagataa tggcggattg tcaggaatca
    38101 atcctgattt tgttatcgga tcagtctcat tgattttttg gacattgact ctactgacaa
    38161 caatcaaata tgtcgtgatt gcattgaatg cagataacca tggtgaaggt ggaattttct
    38221 cactctacac acttgtccga aaaggtggga aatatttgat cattcctgca atgatcggag
    38281 gagctgcctt actagcagat ggggtattga cccctgctgt gacggtaacg actgcgattg
    38341 aaggcttgcg aggaattccg cagttttttg accggttcgg taataaccag aacgtgatcg
    38401 tcattatcac tttagttatt atttttgttt tattcatggt ccaacgcttt ggtacagata
    38461 ttgtcggaaa agcattcgga ccaatcatgt tcgcttggtt tactttttta ggcgtaatgg
    38521 gattaatgaa cttcagtcaa gactggacag ttatccgtgc actgaatcct tattatgcta
    38581 tccagctgct ttttagtgca gataacaaat taggcttgtt cattcttgga aatattttcc
    38641 tggctacgac aggtgcagag gcgctttatt ccgatcttgg acatgtcggc aaacgaaata
    38701 ttcgtctgag ctggccttac gtcaaaattt gtttggttat caattatttt gggcaggctg
    38761 cgtggttgtt gaatgtttat caaaaccctg aagcacagca aatcaagaac ctgaatccat
    38821 tcttccaaat gatgcctcaa agttggatcg tgatcggcgt tgcttttgca acagtcgctg
    38881 cagtcattgc ttcgcaagca ttgattacag gttcgtttac gctagtttca gaagcaatca
    38941 agttgaaact gctgcctcgg ttaaagatca tgtatcctgg gaacagtatc gggcaaatgt
    39001 atatcccagc agtcaatctg attttatgga tcgcctgttc tctagtggtt gtcacattcc
    39061 gaacgtctca tcatatggaa gctgcttacg gtctatcgat cactgtgacg atgttgatga
    39121 caacagcact gctttacttt tatcttatcc aaaatgggca ttctcgttgg cttgcatatt
    39181 tagttacctt tttcttcggt gcgatagaag tcgttttctt tatctcaagt gttgtcaaat
    39241 tcttccgagg cggttttgta gccgttctga ttggtttgat catcttagtc gtgatgttta
    39301 tttgggaaca agggaacatt attcgcgaat cgtcaaccga ggatgtgtct ttgagagatt
    39361 atatcccgca gcttagagaa ttacgtgatg atacttcttt accaatctat cagacaaatg
    39421 tggtcttctt ggttcctgat atggctgaag ataaagttgg ccgacagttc atctattcga
    39481 ttttagataa acggcctaaa agagcacgag tctattggtt tgttcatgtg gaagtgacgg
    39541 atgagccata tacgaaagaa tatcaagtag atatgatgga cactgatttt attgtccaag
    39601 tgaatctgtt cttaggtttc agggtccaac aggaaatcaa cgtatatgtt cgccaagtca
    39661 tccatgattt gatgaaacaa ggccgtttgc caaaacagcc acaaagatac tctctgacac
    39721 cagggcgaga agttggcgat ttccaatttg tcctgattga tgaagtagtt tccaatgtga
    39781 caactctagg aaaatggcaa cgtcaaatca tgcaggcaaa actggcaatc aaaaaaatcg
    39841 ctacctcgcc agaaacatgg tttgggctag agtacagcga agtaaaacat gaaactgttc
    39901 cgcttatcat tggaaatact cggaaaacat ggttgaaaga gcggttgtga aagtagcgct
    39961 ttgacctgaa ctaatgtcga atgtcagcta cttgaacacc gtttatcaga ggtcatgaaa
    40021 aagctgtact gcaacaagca gtaagaacga gcagataaaa acagcttctc atgtttttca
    40081 tctgtttggg cttaatgccg tagatgcaag cttttgaata ccgtttttat cagaggtcat
    40141 gaaaaagctg tttagcaaca agtaacgcaa tgattttgaa gtgataagga gatgtggctg
    40201 aaaaatgccg catctccttt tttattccta aatatgaata cgcattattt tcaatctttt
    40261 tgtagaaaaa gggtacaata gaaaaagaga aaggcgggag aatatggtta tcaatttcat
    40321 tattttattt ttgatgattg caattacttc attttttgta gcaagtgaat ttgctttagt
    40381 gaaaatcaga cgatcaagat tggaacaact agaaaaggaa aatgtaaaga acgccaagct
    40441 agctcttcat gttacacacc atttagataa ctatttatca gctagtcaat taggaattac
    40501 gctaaccggt ttgatcatcg ggtgggtcgg tgaaggatct gtcgcggctt tactagaacc
    40561 agtgatcggt aaactacctt ttagttcggc tattagcagt acaatctctg tggcgctggg
    40621 atttatttta gttacgtata tcgatgtggt tattggcgaa ctgcttccta agagctatag
    40681 tatcgtcaat acggagaagg tcgtcttgtt cgtagttaaa ccacttcatt atttttataa
    40741 agtaatgttt ccttttattt gggtattgaa tcattcagct gcagggctag ggaagctatt
    40801 aggtgtgcgt ctcgtatctg aaggagaaga gacattgtct caagaagagc tgacattagt
    40861 cgcattgaat tcttatgaaa aaggagagtt gaccaaagaa gaatattatt atttggaaaa
    40921 cgtgtttgaa tttgatgata ccttggcaaa agatatacaa gtagaccgta cgtccatgca
    40981 agtattcgaa gcttcagaaa ccgtcaaaga agcgataaaa gcttcgattg aacaaggaca
    41041 tactcgctat ccggttatct tagaatcaaa agacaatgtt ttaggttatg tcaccttgcc
    41101 agatttgatc aagcaatctt ataaagatga ccagctgaca gtagaacagt tgattgaaga
    41161 gccgatcgta acaactgaaa cgatccctat aaaaaaatta ttgacgatca tgcgaaaaaa
    41221 gggtaagcat attgctatct taaaagatga atacggaggg acaagcggct tagtgacgat
    41281 tgaagatatt ttagaagaaa tcgtcgggga aatccgagat gagacagatt tggacgaagc
    41341 attgatagcg gaacagtcag atggctctta tatcatctcc ggcaaactaa cattagatga
    41401 tttccagcgt tattttcatg tagagattcc agagtttgaa gaaacgaatt ttactacact
    41461 tgcgggcttt gcttctagcc gatataaaga aataaaagca ggaacaatca ttgagattgc
    41521 atcattccgt ttcacggtat tagaatacca gcatgcacat atcgattatt tcaaagtaga
    41581 gtccacggaa agaaaaacag aataaaagaa aaaaggctgt gacatttttt gtcacagcct
    41641 ttttgttatc taaaaaacct gttttcggta aacgaagaag atattttcaa taaaagtttt
    41701 catttttagc cgcaacgatt tcttttaatc aaggctatct tgcttctgca tgttctaatg
    41761 tgaaatgttc ctcttcaccc atgtgtttca attgtttcat cgaacgcata taagagtaaa
    41821 gcaacacggc aacagaaccg atccaagcta aaggagaagc tgctgctgct cctgggtatc
    41881 cccacattcc tgtaagaacg atagctgcaa aagaacgcat aagcaattcc atcataccgg
    41941 cgatcgtagg gatcttgctt tgtccaagcc cttgaagtgt gtagcgtaaa atgaacagga
    42001 ctgctaagat ccagtaaaga gacccattga tattgaagta ggtttgtgct aattcaaata
    42061 cacgtgtttc tgatgggtta acaaacaatt gaacaaagaa atgaccgaag aaaatgacga
    42121 tagcacctgc taagagacta aatccgacac tcatcagtaa agtttgacgt accccttgca
    42181 agattcggcc atattctttc gcaccatagt tttgtgcagt gaaagttgcc attgcaatac
    42241 caaatgacat catcggctga tttgcaaatt ggtcgatacg accagcagcg gcttgagcag
    42301 ctacgacatc tgtccctaga ctatttagtg ctgcttgtaa cacgatagca ccaacagcga
    42361 tgatcgaaga ttgaaacgcc attggcaaag cagcatttag gtgtacagca aactcttctt
    42421 tttcaaattt gaaatctttt ttgcgtaact gtaacaaagg catttttttc ttgatataca
    42481 ctagacacag tacgctggaa gaaacttgtg cgattactgt agcaatagct gcaccttcca
    42541 cacccatgcc aaaatagata ataaagatca aatcaagtac gacgttgatg atgaccgcaa
    42601 tgatcagaaa gaatagtggt gtgcggctgt caccaagtgc gcgaatgaca ttagaaagca
    42661 aattgaaact gactgatgca aagatcccta ataaaataat tgaaataaat gtttgtgctt
    42721 gatcaagtat ttcaggagga gtttgcatca attgaagcat cggacgaata aacaggagac
    42781 ttaggacagt taaaatcaca gtgacgacaa gactaatgac aacactagca gcaaaacttt
    42841 tcttcagacc ccgataatct tttgcaccgt aacgttgtgc ggtaataatg gctaaaccag
    42901 ctgttaaacc ttgggcaaag ccaatgatca aaaatgtcag gcttccagtt gcaccaaccg
    42961 ctgccagcgc atttttacct agcgtctgac ccacgatgat catatcgatc atattgtaga
    43021 actgctgaaa aacatttccg atcagtaaag gaacagtgaa catcaaaatc agtttagcgg
    43081 ggcttccttt tgttaaatcg cgcatctttt aaactcctta tatctttaaa atttagttag
    43141 tagtatatag cgtttatcct gagaatacca attagaaatc aatgataatt tatgaaactc
    43201 cataaaaaga agccaagaat tgagtcaaag aatcaacaac ttggcctggt ctgtaaaata
    43261 agggacatcc acgtttatct atcaccttaa tattgtctaa tctcacttgg taaaaggatc
    43321 gtttctctcg taccgtcatc ataggcgtat acttgagcag gaaattggtt cgaataggca
    43381 aacggcaaat caatatccat ttccacattg cttcctgctt gagaaaaatg catcgtcact
    43441 tttccacgat tttcgatcaa atcaaaggtt aatatatttt ctaatggaat gactccctta
    43501 agatctaggt caataataaa ccatatactg tcaatcaatt catctggcaa acttgatacg
    43561 acaccaactg aagcgtaacg gttgcggctg ctatcaaaac tttcaaacat ctgtttaacc
    43621 tccttcgaat caacgaatgt tttattttta taattaatcc taggataaac tagaaatact
    43681 tacttcaacg agggttcatt ctaataaaga atcaggaaaa atgcaacaat aattgaatac
    43741 tttttttcaa agtataaatt tttataaagg tacgataaaa gtatgcgagg aaaagcttgg
    43801 taaattagga tttttcgttt gtaaagccat ttacaaaagt ggaagcccca tatgaaaata
    43861 aacgattaga aataaaaaag gcgtgttaaa agctgctgac ccgccgcttc taacaccacc
    43921 tgattgtttc agtattattc ttctgttgaa ccgatcactt ctggttcgcc accttcacct
    43981 gtgctttctt cttcttcact ttgagcgact acagcagcga tttgctcttc actgtcggtc
    44041 acgaatttgt aatcgtcgtt ttttggaaga tcggctactg taatagaatc acctaattcc
    44101 aagtttgtca cgtcaacttc aattcgttca ggcaatttgt ctggtgtagc agatacgact
    44161 actgtataca agttttgagc taacactcca ccagatttag cacccactga ttcgccaaca
    44221 agaacgactt ctgtttcgac ttctgtttct tccgacatgt ttacagatag aaattctgca
    44281 tgttcgaaat gattggtaaa agtgttcgtt tggatcttgt gaaccaatgt attgactttt
    44341 tgtccatcga tgtccatcgt gatgactgtg ttcgctccat gttcacgcaa caatttgctt
    44401 agtgtcaaac catcgaatga gataggggta ctttctactt tatacccata aacaacagct
    44461 ggaactttcc cttcgtgacg aagtttgttt cttaatgaac ggggacgtac ttctctttta
    44521 cttacttcta atgatactga cataaccaaa attcctcctt aaaatgtgac tgtctgcttt
    44581 ggtaacggac agattttatt taagtgaatt ctaaaggcta atctcgtgca catcatcgaa
    44641 ggcagggcgc ttaaaaaagc gcaaaaggag agatgcgcgc atctcccctt agaaagtcag
    44701 gattcaactt ttctccacca ggtcattacg ctgtgtatga gaaatccaat tcactttact
    44761 atttaaccgt aacgtgaact gttaattaag tcaaggaata actatgatga tgtatttgca
    44821 agcaagaata ttcaaggtat aattaattag tagtaataag aaaggaaaca gcatgcgttt
    44881 agataaatta atagaagaaa aattagaaac gacacgcaag gaaatgaagc ggctgtttgc
    44941 tttgaagcaa gtgatgatag atggcacagt cgaatttcga caaaatcgaa atgtagatag
    45001 tttactgcat caaatcgaag tagcaggtga acacttagaa acaaatgagt cctattatct
    45061 tctcaataaa cctgaaaaag ctgttacagc tgtatcagat ccagaaaaga cgacagtaat
    45121 cgatctgatt gcaagtgccg atcgtttcca accattatat ccagtgggaa gactagatag
    45181 agatacaaca ggactattgc tgatcacttc gaatggacaa ttgggatatg aaatgctact
    45241 tccagaaaaa aaggtttcaa agacttatca agtagttgtg aacgaaaggg tgacaccggc
    45301 agacgtaaca gcatttgaaa atggaatcgt attcgctgat gggtatcaat gtaagccggc
    45361 tgatttaaaa atactcaaag cagacaagca ccaaagtacg gttttattga cgatccaaga
    45421 aggaaaattc catcaagtca aaaagatgtt cttagcccaa ggaaagaaag tgaccgcatt
    45481 gaaacggcta agcatgggac cattggaatt agatgaacag ctaggagtag gcgagtatcg
    45541 atcgttgaca ttagcagaga tgaaaaagtt aagtatttat tttaaatagg aggtcaaaaa
    45601 gatgaaatat aaaactttat tgtttgatgt agatgataca ttgttagatt ttcaattaac
    45661 tgaagccaat gctttaagtg ctttgtttgc agaacaagga atcacattga caccagaaat
    45721 cgaaaccagc tataaggctt tgaatcatca tttatggcag gagtttgaaa aaggcagact
    45781 atcacgagaa gaaataatag gcagtcgttt tgggttactt ttccagcaat ttgggaaaac
    45841 agtagatagt gatcaaatgg aaaaacgcta ccgccactac ttgaaccaag gtcatgatct
    45901 tgttccagga agtctagaaa tcctgaaaaa ggtccatccg catgctgatc tttatattgt
    45961 gacgaacggt gtgtcgcaca cgcaacatcg gcgattaaca gatgcaggaa tgcttgatta
    46021 cttcaaggat atctttgtct cagaagctgt cggagcgcaa aagccgatga aagaattttt
    46081 tgatcatgtc ttttcccaca ttcctaattt tgataaaaag caaactgtga tcattggtga
    46141 ttctttgact tctgatatca aaggaggaaa tatggcaggg atcgatacga tttggttcaa
    46201 tagaaataaa ttaccagaaa tcgaagaaat ccagcctact tatcgaatcg attcattaga
    46261 ggaactttat tcattattgg aaattgaaaa ggattaattt tcagaaaaat atagcatttt
    46321 cgtgtttttt cgctataata gattagaatg aaaaaacgga tacgaaagag gttttagtca
    46381 atgacaaaaa gcaagccaat tatcattggt gtgacgggtg gatccggaag cggaaagaca
    46441 agtgtcagcc gtgcgatttt caacaacttc ccggaccatt ccatcatgat gcttgaacaa
    46501 gattcttatt acaaggatca gagccatttg agttttgaag aacgattgaa cacaaattac
    46561 gatcacccat ttgcctttga taatgatctg ctgattcagc atgtaggcga cttactgaac
    46621 tataaagcca ttgaaaaacc cgtgtatgac tatgtagcgc atacaagaag tcaggcaacg
    46681 atcattcagg aaccaaaaga agtgatcatt ctagaaggaa tcctgatttt agaagacgaa
    46741 cgtctgcgtg acttgatgga tatcaaagta tacgtagata cagatgatga cattcgtatc
    46801 attcgtcgta tcaaacggga tatggaagaa cggggacgca cattggactc cgtgatcgaa
    46861 caatatttga cagttgttaa accgatgtat catcaattta tcgaaccaac gaagcgctat
    46921 gcggatatca ttgttccaga aggcggagaa aaccacgttg ctattgattt gattacaaca
    46981 aaagtagcta gtttcttaaa ccataaatag tgcgcagcga aacagttgaa cggactgcga
    47041 ccgtttgaaa agcaaggatt ctgctttttg aacagtcacc agccaactgt ttttttattt
    47101 ataacaagag gttgtgaaaa cagcatcttg acctaagtat taaaaagaag aaacggaaaa
    47161 tagctgttta tattttaccg ttttttgagc taataccgaa ggtcagctga ttgagcaccg
    47221 tgaagtagag gttgtaaaaa agctgtcttt gcatcaagcg ataagagcat ccaaataaaa
    47281 cagctcctca cgtttttcgt tgggttgggc ttattatcgt agatgcaagc ttttgaacac
    47341 cgtttaacga gaggttgtaa cagaagtggt cagatgcaat aaataagaag aaacttacga
    47401 aaattatttc tcgaatttgt gtgagatttc gacttatttt tttgaagaag ctcttttgtc
    47461 gcaccccc
//
LOCUS       DAFEML010000017        47294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFEML010000017
VERSION     DAFEML010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.017"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(147..863)
                     /locus_tag="LP468_001086"
     CDS             complement(147..863)
                     /locus_tag="LP468_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2080639.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(864..2687)
                     /gene="glpO"
                     /locus_tag="LP468_001087"
     CDS             complement(864..2687)
                     /gene="glpO"
                     /locus_tag="LP468_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL2080640.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(2701..4197)
                     /gene="glpK"
                     /locus_tag="LP468_001088"
     CDS             complement(2701..4197)
                     /gene="glpK"
                     /locus_tag="LP468_001088"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL2080641.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGGIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(4333..5793)
                     /locus_tag="LP468_001089"
     CDS             complement(4333..5793)
                     /locus_tag="LP468_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080642.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(5783..7078)
                     /locus_tag="LP468_001090"
     CDS             complement(5783..7078)
                     /locus_tag="LP468_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2080643.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(7410..8087)
                     /locus_tag="LP468_001091"
     CDS             complement(7410..8087)
                     /locus_tag="LP468_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL2080644.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(8117..9208)
                     /locus_tag="LP468_001092"
     CDS             complement(8117..9208)
                     /locus_tag="LP468_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL2080645.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(9309..9743)
                     /locus_tag="LP468_001093"
     CDS             complement(9309..9743)
                     /locus_tag="LP468_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2080646.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(10327..11784)
                     /locus_tag="LP468_001094"
     CDS             complement(10327..11784)
                     /locus_tag="LP468_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2080647.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(11781..13676)
                     /locus_tag="LP468_001095"
     CDS             complement(11781..13676)
                     /locus_tag="LP468_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2080648.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(13734..15509)
                     /locus_tag="LP468_001096"
     CDS             complement(13734..15509)
                     /locus_tag="LP468_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2080649.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(15559..17055)
                     /locus_tag="LP468_001097"
     CDS             complement(15559..17055)
                     /locus_tag="LP468_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2080650.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(17249..18871)
                     /locus_tag="LP468_001098"
     CDS             complement(17249..18871)
                     /locus_tag="LP468_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2080651.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(19321..20634)
                     /locus_tag="LP468_001099"
     CDS             complement(19321..20634)
                     /locus_tag="LP468_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2080652.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(20879..21103)
                     /locus_tag="LP468_001100"
     CDS             complement(20879..21103)
                     /locus_tag="LP468_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080653.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(21123..21545)
                     /locus_tag="LP468_001101"
     CDS             complement(21123..21545)
                     /locus_tag="LP468_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL2080654.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(21687..22397)
                     /locus_tag="LP468_001102"
     CDS             complement(21687..22397)
                     /locus_tag="LP468_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080655.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(22415..22911)
                     /locus_tag="LP468_001103"
                     /pseudo
     CDS             complement(22415..22911)
                     /locus_tag="LP468_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(22948..23400)
                     /locus_tag="LP468_001104"
     CDS             complement(22948..23400)
                     /locus_tag="LP468_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2080656.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(23535..24140)
                     /locus_tag="LP468_001105"
     CDS             complement(23535..24140)
                     /locus_tag="LP468_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2080657.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(24590..25210)
                     /locus_tag="LP468_001106"
     CDS             complement(24590..25210)
                     /locus_tag="LP468_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2080658.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(25212..26081)
                     /locus_tag="LP468_001107"
     CDS             complement(25212..26081)
                     /locus_tag="LP468_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL2080659.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(26104..26511)
                     /locus_tag="LP468_001108"
     CDS             complement(26104..26511)
                     /locus_tag="LP468_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2080660.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(26530..27819)
                     /locus_tag="LP468_001109"
     CDS             complement(26530..27819)
                     /locus_tag="LP468_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2080661.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(27846..28148)
                     /locus_tag="LP468_001110"
     CDS             complement(27846..28148)
                     /locus_tag="LP468_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2080662.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(28173..30266)
                     /locus_tag="LP468_001111"
     CDS             complement(28173..30266)
                     /locus_tag="LP468_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2080663.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(30755..31483)
                     /locus_tag="LP468_001112"
     CDS             complement(30755..31483)
                     /locus_tag="LP468_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL2080664.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(31629..34250)
                     /locus_tag="LP468_001113"
                     /pseudo
     CDS             complement(31629..34250)
                     /locus_tag="LP468_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(34364..35695)
                     /locus_tag="LP468_001114"
     CDS             complement(34364..35695)
                     /locus_tag="LP468_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080665.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(35661..37139)
                     /locus_tag="LP468_001115"
     CDS             complement(35661..37139)
                     /locus_tag="LP468_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2080666.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(37444..39279)
                     /gene="tdc"
                     /locus_tag="LP468_001116"
     CDS             complement(37444..39279)
                     /gene="tdc"
                     /locus_tag="LP468_001116"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2080667.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            39749..41176
                     /locus_tag="LP468_001117"
     CDS             39749..41176
                     /locus_tag="LP468_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2080668.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(41268..41633)
                     /locus_tag="LP468_001118"
     CDS             complement(41268..41633)
                     /locus_tag="LP468_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2080669.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(41630..41995)
                     /locus_tag="LP468_001119"
     CDS             complement(41630..41995)
                     /locus_tag="LP468_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2080670.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(42187..42435)
                     /locus_tag="LP468_001120"
     CDS             complement(42187..42435)
                     /locus_tag="LP468_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080671.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            42434..42562
                     /locus_tag="LP468_001121"
     CDS             42434..42562
                     /locus_tag="LP468_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL2080672.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            42619..44313
                     /locus_tag="LP468_001122"
     CDS             42619..44313
                     /locus_tag="LP468_001122"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL2080673.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            44317..44436
                     /locus_tag="LP468_001123"
                     /pseudo
     CDS             44317..44436
                     /locus_tag="LP468_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            44964..46097
                     /locus_tag="LP468_001124"
     CDS             44964..46097
                     /locus_tag="LP468_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL2080674.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            46128..46448
                     /locus_tag="LP468_001125"
     CDS             46128..46448
                     /locus_tag="LP468_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBL2080675.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(46477..46941)
                     /locus_tag="LP468_001126"
     CDS             complement(46477..46941)
                     /locus_tag="LP468_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080676.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(47073..>47294)
                     /locus_tag="LP468_001127"
     CDS             complement(47073..>47294)
                     /locus_tag="LP468_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2080677.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT        13889 a        10040 c         7935 g        15430 t
ORIGIN      
        1 aaactttgtt tattggctat tcgacttact gattagatac cagctacact cacaaaacat
       61 accccattct tctaggtctt atttattttc cacttaacta tagcaagaca cattttggtt
      121 gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc taccgcgata
      181 attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc tgaagttcct
      241 ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg agcagggttg
      301 attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa tccacctaca
      361 gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa cccaagaact
      421 aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg tatagcagga
      481 cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca atgtggcaaa
      541 taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc aatgatgaaa
      601 ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga gactgcagga
      661 ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac agcgagtccc
      721 caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt taaattcaca
      781 gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa ctcccccatg
      841 atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag atctgattct
      901 gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt ccattcaaaa
      961 tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc tcgttcaaac
     1021 aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat ttcttcttct
     1081 aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg tgccatttct
     1141 tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat ataagtagca
     1201 tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac tgtttcttct
     1261 aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc gatttctttc
     1321 gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc tccttctgcc
     1381 atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc tggttctctt
     1441 tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct gttttccaaa
     1501 tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata ttcacttact
     1561 gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc accattgtaa
     1621 tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc ttcgatatca
     1681 ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag ataatctaca
     1741 tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc tgtcgtacca
     1801 aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg ctttcctgta
     1861 tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa atggatccct
     1921 ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg tactttatct
     1981 acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac ttcatctgtc
     2041 agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa gccaaccgct
     2101 ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt atcaatcact
     2161 aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag cccttctttt
     2221 ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt ctcatatttg
     2281 gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac cgagaacata
     2341 ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc tggttttggg
     2401 atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc tactacttcc
     2461 acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga gcgagaggaa
     2521 gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga tgctgctgac
     2581 tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc caattcttct
     2641 tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg gatttcctcc
     2701 ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa gtttttctcg
     2761 gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt cgcggatctc
     2821 gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc ctagcgccgt
     2881 tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt ggaattgcat
     2941 cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct tgattccagt
     3001 gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact gtaaagtagc
     3061 tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc ctcgtgctgc
     3121 ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa cctcatcttc
     3181 gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca tttgaagtcc
     3241 atctctcagc cattgaatcg aagaaccagc cacaaaaata cctccttcta aagcatagta
     3301 aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg ataattgcgg
     3361 tttttcaccg gtattcatga caataaatga acctgtacca taagtattct tgaccatgcc
     3421 tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca tccctgaaat
     3481 tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt ctgagttaga
     3541 agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct cctgatccca
     3601 atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat cagtaacatg
     3661 tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa acatcaattc
     3721 gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc gtatcttcgt
     3781 tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt cttgatagcc
     3841 ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa caactgcatg
     3901 atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct ggttcgttat
     3961 gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc cggcaataac
     4021 tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt cttgcgggaa
     4081 atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt caaagataat
     4141 tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt ctgtcattgt
     4201 gattccctcc attatatgca aacgctttct ttaactactc ttatcatact actgttttaa
     4261 aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt ttattatgaa
     4321 gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt tcaatcgaat
     4381 aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt tgtttctctg
     4441 gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa tctcaatacc
     4501 gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat aaatcggcag
     4561 actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga tcatcaaaag
     4621 aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc ttttcctcgg
     4681 caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg aatgcccgag
     4741 cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct ttccaacaaa
     4801 gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt cttctttgat
     4861 tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag tatctaaaac
     4921 agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt cttcgtctac
     4981 tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat tcagttctgc
     5041 tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa gccggtccga
     5101 ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat tcaatagtct
     5161 ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg taaacgttgt
     5221 ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat tttgcaaaaa
     5281 aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat atcgtatctg
     5341 tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct ctaagagctg
     5401 gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg ctgtcgctaa
     5461 tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa acttcaagct
     5521 ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca acacaagcag
     5581 cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc caatcaattc
     5641 aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct ctctcaaacc
     5701 attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga tctgtaactg
     5761 ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc tttgaccaca
     5821 ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct aactgttcaa
     5881 acgtccatcc ttcttttact gcaattgtca gttggtcaag aaggtggaac atctcttttt
     5941 tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat ttgagtttaa
     6001 ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca attttttggg
     6061 gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag ccaaaccact
     6121 gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta attgtcttgc
     6181 tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt ttttcatttg
     6241 ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt tgagacgttt
     6301 gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt tcttcccaca
     6361 tctgattgtc ggggcgagaa tgattagcca gcaaaacaag atcatagttc tcctttcttt
     6421 tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt tcttctaaaa
     6481 aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt tcaggatcta
     6541 gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt tttcttgatg
     6601 ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca attttctttg
     6661 cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact gggtgaataa
     6721 gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct agaatcaaac
     6781 gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc aatcctatta
     6841 ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct ttcgtgatcc
     6901 aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac ccgctgggaa
     6961 tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc atcaattggc
     7021 gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca atgttcatct
     7081 gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa acacagtatt
     7141 cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc ctctccatca
     7201 taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga agagtatcat
     7261 ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg ccttttacgt
     7321 acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg tgtgtaatgt
     7381 aatagttaga atagacacat catttatttt taattcttta atgcttcaac aactgcttcg
     7441 cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc aatttgaacc
     7501 acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa agcatcttct
     7561 gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt actgaaccca
     7621 gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg caacaatcct
     7681 acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg tgaagcgact
     7741 ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc agcataataa
     7801 accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc caaggcccga
     7861 tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt caaaacactt
     7921 tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc gatcccattt
     7981 tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt aggacgctcg
     8041 atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt cccatcctct
     8101 ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat gggcttggca
     8161 aataaagctc tttatatgct tcttcaaaag gtttcgttac aaattcatcc tcacggtttt
     8221 ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt gctgcaagtt
     8281 ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg acaccaacta
     8341 aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta tcgttgtatt
     8401 tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa tctagttttg
     8461 actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct ggtgtttcat
     8521 attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat tgttcaaccg
     8581 ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc aagctaccgc
     8641 cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc aaatacgtat
     8701 ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt gtggctttgc
     8761 caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt gtttccgcat
     8821 caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat aaagttgctc
     8881 gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct tctccttgga
     8941 ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg ctgagttcac
     9001 ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca gcaccaagac
     9061 ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca ttgaaaaagc
     9121 tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact cctgaaggta
     9181 aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc tctgattaac
     9241 ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac taatttgctt
     9301 aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg ggctaattct
     9361 ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc ccagctacca
     9421 tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga caagcgacct
     9481 tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg agcaatcgtt
     9541 gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc tttttctttt
     9601 aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa cgcttcatca
     9661 gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca ttcatctaac
     9721 gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc atagtatgat
     9781 ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag atttgaaaaa
     9841 aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct tctggaacac
     9901 cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa attttgtgaa
     9961 aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaactgg cttttgaaca
    10021 ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga acagccaaac
    10081 aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca gctgattgta
    10141 caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag gagcaatttc
    10201 aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag ttggcaggag
    10261 aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt cccttatttc
    10321 cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat caaatgattt
    10381 tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat agatatatcc
    10441 ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc cccacgacgt
    10501 ataaccaaat aaatctactc catcttcgat agcttccttc atctgctcaa tatgctgctt
    10561 caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt tgtctatagc
    10621 tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata attgattcaa
    10681 agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg gaagatacgg
    10741 atttttaatt cctccagtta ttaagtttcc ttggacccct tccaaatttt ctggatgagc
    10801 actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt aggctgctaa
    10861 gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa acattcgttg
    10921 cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag aagttctttg
    10981 ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa gaagctgata
    11041 gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt ttgtagctaa
    11101 agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca aatggggatg
    11161 gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt tgatctcatt
    11221 gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt cagcgaaacg
    11281 aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa ccaaatataa
    11341 cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta gacattcgtc
    11401 aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat caccatgagg
    11461 aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt cagcaaataa
    11521 acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag gataataata
    11581 cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat gccattgatc
    11641 tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca cagataatcc
    11701 tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc cgccccataa
    11761 aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt tcttgtttga
    11821 ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt aacaataacc
    11881 attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc catcaataaa
    11941 tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt gccatttaaa
    12001 ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact gactacccca
    12061 attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacaggact gtagattttt
    12121 ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa tgttggatcg
    12181 tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac tatatccttt
    12241 gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat acaggaactg
    12301 atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat ataaatcggg
    12361 aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc accagctact
    12421 ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata tttaagagtc
    12481 acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc agataaagat
    12541 aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc tcctgcttgc
    12601 gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa agaaagattg
    12661 ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac ttgccaaaat
    12721 ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa atatccagct
    12781 gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaagt aattgggacc
    12841 atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg caagcttttg
    12901 cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg aataaccgta
    12961 cttgtatatc ttgctagaat cacgggcatc cctagaaatc gcaaggttat gctatcacta
    13021 tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc gatgaaacga
    13081 tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa atagaaaaat
    13141 gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa taaattcaaa
    13201 ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac gcctaaagtc
    13261 ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt tttctcagtt
    13321 cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa tacgtcatac
    13381 acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc gactacagtg
    13441 atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc ttttagggta
    13501 aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc tccgacaaat
    13561 cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt gttaattaat
    13621 gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt ctccattcaa
    13681 ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt tacttagccg
    13741 agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata gtcaaaggag
    13801 acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc aagctgatac
    13861 tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt ctcggcattt
    13921 aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga atctatcttt
    13981 ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt tgttttcttt
    14041 ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccga agattcaaac
    14101 tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag ctcttgctca
    14161 gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa aagatacact
    14221 ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg tttttttagt
    14281 gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg ttttcgaaaa
    14341 ggattcaacg cttcggcaag atacaaaacc aaataagcgc tttcagctaa attgggacgt
    14401 aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg ataacgggag
    14461 atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct cgttttcatt
    14521 tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac aggaagatct
    14581 aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc tttgtttttt
    14641 tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc ttgtttttct
    14701 tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt ctctaccatc
    14761 ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg aagaatggtc
    14821 aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata attatatgat
    14881 ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa aattgtactg
    14941 atttgttgag gcaaccttgc gtgttggatc accgtttctg ttccaacaag agataagaaa
    15001 attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga aacttccagt
    15061 tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa tgatacggct
    15121 gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc tttttgaaac
    15181 aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat tttatgtttc
    15241 gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa aaaataacct
    15301 gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat atttttgatt
    15361 tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc gcttgttatc
    15421 caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt taagtccatt
    15481 tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg acaatagtca
    15541 cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt taccattaga
    15601 ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa agcttccgct
    15661 cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt cccctgttcc
    15721 tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc aaccatcttt
    15781 tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt ttggatcgtg
    15841 gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa ctatgaataa
    15901 tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta gaggatcaat
    15961 tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga aaccatttgc
    16021 tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac gataataact
    16081 aaatgcaata taatctaccg tgttagcttg caagtactgt tcgtctccat ctaacattac
    16141 tggtgcacag tcttcttcct tccatatcct gtaaatataa gctggataat gccctcggca
    16201 catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa atacattctc
    16261 tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa tacccatctt
    16321 agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta gaaacatatg
    16381 atgacaggct tgataaatct ctttttttgt tagtgtagca atgggttcaa gtttatctct
    16441 agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat tattgatctc
    16501 attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg tctgcgcata
    16561 aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc ctaccaatgc
    16621 taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc gatttaatgt
    16681 attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt cgtctcctct
    16741 tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta actccttcag
    16801 taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag aaagataatg
    16861 gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact gaatactagg
    16921 atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc cgtcttccaa
    16981 ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat tttctggaaa
    17041 tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt gaagtatagc
    17101 tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa aaaattgaat
    17161 gctactcttc atttttaata tttatatata acaaatacat aagacgatcc ccgaaagaaa
    17221 acactcgtta accatctaag caaacgattt attttacttc caacacaaat gcttcataag
    17281 gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac acaataaccc
    17341 ttaaagcttc acgtggaaca gtgaacgtct gcttttcact ggacatatta caaataacga
    17401 gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc gtcttttcca
    17461 ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg atcaatttct
    17521 tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg atttctttat
    17581 aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt tcacgggcgt
    17641 tccattgcat aggcgtccta gcattgtctc ttcctttcgc attgattgat tccaagattt
    17701 cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc tcaatatctt
    17761 ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct ccttgataga
    17821 tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca ctttcttttc
    17881 gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga ttattccaaa
    17941 ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat acttttttca
    18001 gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc tgatctaatc
    18061 ctatgtgttc gaattggaag accatggata attcatttct tttaggattg gaataaagtt
    18121 tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt ttgtcaccaa
    18181 aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta cttgtgattt
    18241 ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagcca ccaatacctt
    18301 tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta tttttccaat
    18361 tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt ttttcatcca
    18421 actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt ccattgaccg
    18481 gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg gcctcaatga
    18541 accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata cggatatttc
    18601 ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat tctgccatga
    18661 ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg tatactggag
    18721 aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa ataatccccc
    18781 gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag atttgataaa
    18841 caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg gatgtttcta
    18901 ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc tttcaaatag
    18961 ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg aaattccctc
    19021 aactgttttt tgaaaggatt gatttattca gggaagaatg ctgatttcac aacttcttta
    19081 taaacggtgt tcactcagct gtccctcggt attagctcaa aaaacggcaa aatataagaa
    19141 actatttttt tcgttttttt ctctaatact caggccagaa cactgatttc acaacctctt
    19201 tataaacggt gttcactcag ctgtcccttg gtattagctc aaaaaaaggc aaaatatgag
    19261 gaactatttt ttcgtttttt tctctaatac tcaggccaga acactgattt cacaacctct
    19321 ttatttcaca ttcaatatcc acatgaatcc catgaataca aagaacagac catacatgat
    19381 gggagatact tcttttcctc ttttagctgc taacatggta attggataga agataaaacc
    19441 taatgcaatc ccatctgaaa tactataagt caaaggcatg ccgatcaaga tcaagaatga
    19501 agggatcgca atctctaagt ttccccattc gatttgtcgc aaagattgtg ccatcaatac
    19561 tcctaccata atcaatgctg gtgcagttac ttgtgaagta acaactgata gtaatggaga
    19621 aaagaacaag cctaacaaga agaaaatccc tgtagtaata gctgtgatac ctgaacgtcc
    19681 tccaacggcg ataccagctg atgattctac aaatgcacca acaggagaag tacctaataa
    19741 ggaacccgca agcatagctg ttgaatcaga agctaaagct ttccctacac gaggcatctt
    19801 gttgtctttc atgaaacctg cttggtttgc taatccaact aaagttcctg ctgtatcaaa
    19861 gaaagtcaca agcaagaatg tcagcactac gacccacatt tgaagagaat tgatgtcccc
    19921 tacatgtttt aatgcaacta aaaatgttgg tttcaaactt ggtgctgcgg caacaatttc
    19981 agaaggcatt ggaatcaaac ctgtgaccag acctaaaatc gttgtagctg ccatcccgat
    20041 gaagatgcca cctggtacac gccgaacaag caagatagca gttacgacta atccaaaaat
    20101 cgtcaaccaa gtagaaccaa cgttgagtga tcctaatcct actaatgtag attcattcga
    20161 aacgatgatc ccaccttcgc tcagaccaag gaaagcaata aatagaccga taccgccaga
    20221 aatcgcatat ttcaaatctg ctgggatcgc atcaatgatc atttcccgca gcttgaagat
    20281 tgtgatcaaa ataaaaatca aagaagcaac gaatacgccg gctaatgctg tttcccatgg
    20341 aatccccatt cctaaacaaa cagaataagc aaaaaaagca ttgatcccaa gagcaggtgc
    20401 cgttccaatt ggataacggg ctaatacccc cattaaaata cagccgatcg cactggctaa
    20461 tgcagtcgca gtaaacactg ctccttcatc cattccagaa gcacctaata cagttggatt
    20521 tacaaataag atataagcca ttgagataaa tgttgtaaat cctgccagta cctcacgttt
    20581 taccgtggtg ttcaattttt ctatttcgaa gtaggaaagt attttttcct tcatcttcca
    20641 tccccctaaa tccgaacatt ataaataaag tccgttaaaa tttcgattta ttaataaaac
    20701 aacgtgtttt atcatatact aaaacaaaac ataagtaaac aaaaaattcg gattttaagc
    20761 aaaatccgaa cgttccatct gattaaatcc ctttatctca aagttcatga acattcactt
    20821 tggattacaa gaatttcttt attgtgttaa taaagtttct tcattctagt ctcaaaaatc
    20881 aatagtgtga tttgatttta ccatttcgtt tctgttcttc tttgatgaat tcttttgtat
    20941 cgacaggatt cagattattt agtccgccaa aacctgtatc gaccattttt ccccagcctt
    21001 ttgtcttctt ttttcctgat ttgagattct ttgctcgaag cttctcacta tgttttgctc
    21061 gccgatactt caaataacct tctaatcttc ccattagatc cactgtttct cctccttttt
    21121 attcaatcag acgactcagc ttttcctata acaaaataat tgccttcagg gtccgaaaaa
    21181 ttgaaagtca agacgccatt gttgtctgtg atttctcctg gttcttccat gttctcgtag
    21241 atagtttcaa attcatccgt aaaaaatact aaagaaggcg gtggtcctaa tacctctggt
    21301 gaaaacttct gcacaaatac ttttgggaat acgcctaatt ctaattcttt tgagatgctg
    21361 agtacaatac tcttaaattc ttctggcaat tcgattgttt cagaaatttc tgcaccaatt
    21421 ttttctacaa agaatcggca aatcatctct acgtcattga cataaagcat cacacgtgtt
    21481 ttttgtatca tcgtttgacc cttctttcta tttgattttc tttcctgtct ataaactgat
    21541 tccattatat cacgaaagcg caaacacctt gtgtttgata ctattcaaga aaaataaagc
    21601 aatagtttct aggattgctt tcctccacaa acttttttta caaaaaaaaa acggcaatga
    21661 atgccgctct tcttatttcg attcttttat aattctgctt ctgattcatc tttggttagt
    21721 gtgtgtctaa cactagttac gccaaatgtt tgatcgattt tttccttcaa cgcttcgatt
    21781 gcctgtgcgc cacgtgccgc ttgttcagca ttgatggatt caatgaccag caccgctgct
    21841 tgtgtttctt ccgtcagcat cgttctttgg gcttcacgcc agttgagaca gcgacagatc
    21901 gctccttgtt catcatagta gatgatttct tccggaagtg ccggagcatc ggaatctgca
    21961 cctaaaggca ggaatgattc gtcaccttgg gcttttccta aatgcagatt tcctgcgatc
    22021 ttttcgatat cttctccgcc gcaaggtacg ccaaaagaca aggaaatact attatagata
    22081 tctacaagcg gattgattgg gaaaaattcc cgttcttgat ttgcacgttt cagtaaagct
    22141 tcaatagaag aacgtgcacc ttttttagtc ttgaatgtgg taaatgcctg acgccactga
    22201 gcaatgactt cgttttggct gaatgtttct tctgtaaggt aatttcttgc ttcttttgct
    22261 gcctcattca ataattgatg atacgtttct tcactttctt ttgttacgtg gttatcgata
    22321 ccatttacgg ataagatttc gatggttgct tcaggaaata cttcccagaa attggtatcc
    22381 actattactt ttttcatctg ttcacacctc ttgattagaa taattgcttg atgaatagat
    22441 agtctgtttg gggatcatct cccatataaa aaacatgttc gctgtatttg ataaatcctt
    22501 ttttacgata aaaagcgagc gcaacatcgt tgtgttccca aacaccgagc caaatggctg
    22561 ttttttgctt ttcttttgct ttttcaatag ctgtatctag taaaaatgta ccgatacctt
    22621 gatgtttaaa tttttttcgt acatagattc gctcgatttc taaaaaatga tcagccattt
    22681 cctcagattg actcgttcct gtatttagtt tcaggtaacc cgcaggctct tgatcgatac
    22741 tcactaggaa aaaatctgtt tctttatctt ttagctcttc tgtaagtttt tctagtgcat
    22801 aagcttgtgt caagtaatca gctaaatgct ccggtaatta tcttttccaa atgtatctgt
    22861 aaatgtttcg atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat
    22921 ttcgtattta ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa
    22981 attccaatct tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc
    23041 ttcttcgtca gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat
    23101 gaaaggatag atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc
    23161 tttatcttcc aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt
    23221 cgttgtacga tctactttga tcatttctgc tagtttttct tggatgattc caggattttc
    23281 gcaaatacgt actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat
    23341 attgctaata gagtctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat
    23401 ttcatcccac ctttattttg tttgtaagac tagtttacct ctttttgttg caaatgcaac
    23461 tatttttaat aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc
    23521 ttttacgaaa aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt
    23581 ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg
    23641 ttggaagttt cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa
    23701 acaagtttat aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact
    23761 gctcgcaact gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca
    23821 ttttcttcag gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc
    23881 cgtttatctt cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact
    23941 tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct
    24001 tttcctattt cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta
    24061 tcaaatacat cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat
    24121 tgagccaact tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat
    24181 caagtataga agactggttt aattacggca aataaatata atgaaatctg caataaataa
    24241 aagaatgtta aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat
    24301 ggcgttcaaa agcttgcatc tgcggtaata agccccatca aacgaaaaat atgacgagct
    24361 attcttgtct ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact
    24421 aaacggtgtt ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa
    24481 gctgtttctt tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc
    24541 ggtaaacggt gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt
    24601 cattgatttc tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg
    24661 ttacatcaaa ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga
    24721 tctttttgaa tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt
    24781 caccatagtg ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt
    24841 tgtaccgacg ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat
    24901 atccgtatct atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact
    24961 cggacacaat cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag
    25021 gataaacttt cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt
    25081 ctgcatagta ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc
    25141 gtagtttatt cataagatat gtttttcctg taccaggact accagccaga agaatgaaat
    25201 actttttcat ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca
    25261 atcttatgct tgacaatttc ttttactgct ttatttgctg gaatcacatt atggcgaaga
    25321 gacttgttga tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa
    25381 agctccgttc caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct
    25441 tctttcacac ctgttcctcc atggataact agggggacat caactactgc atcgatttct
    25501 ttcagcaagg gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata
    25561 gcaatagcta atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt
    25621 gtatatacct tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca
    25681 agttctcctt ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc
    25741 aagatatttt ctttgaaagg tagatgggac ccgtcataca tgacagaagt atatccgcta
    25801 tcgattgctt ctttgatatc atcaaagtct cgggcgtggt ctaagtgtaa gactgcatca
    25861 accatttctt cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat
    25921 ttagcggtat cgacacttgt ttgaataatg attggcgaac ccatttcttt tgctgcgcct
    25981 agcatggcag gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac
    26041 tcttctgctg tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc
    26101 tttttatttg tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt
    26161 gcccatgtag taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg
    26221 gttatagagg ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaagct
    26281 cttttctaaa tattggatgg cttgatcgtt ctcatgcaat tcagaaaatt taagtccaac
    26341 ttgttcataa agttccgcta atttatgcct atcttgggta gtggaaatct cttgtttcaa
    26401 ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt
    26461 tgccagaact tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc
    26521 tactttcaat taaaacgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc
    26581 ggctactgta tctacatcgg ttgctgtagc attgatgaat cccatcgaat taaagatcgt
    26641 tactagcaaa gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc
    26701 tcctcggcgt ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt
    26761 ggttagcata ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat
    26821 aatcgtacca atcgttgtcg taatgaaacc taaaatgacg gcatttgggc tataaggaaa
    26881 gaaaactgga caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg
    26941 aaatgccggc acgatttcac ctaacagtag acgtacacca gctagcaata tatacacacc
    27001 cactacgaat tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa
    27061 ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac
    27121 gaccatgaca gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc
    27181 ttcgatcgac tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa
    27241 taagtacccg atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg
    27301 aatgatcggt tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc
    27361 gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt
    27421 tgccatccat aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc
    27481 caaaataata ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc
    27541 caaatcattc attgcttgat cattgataga ttcaatagaa gggatgatcc cttgcatatg
    27601 aaatccttca gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc
    27661 ggcactcaat acttgaaatc ctaggagtgt ttttaacgtg ccagagatga cttgtcctgc
    27721 tgatttcttc tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg
    27781 agtcaaaata ttttcgatga taaaattgat aacgctcatg tttttaccct cttttctttt
    27841 tgtatttaga taactccctt atcttgcaga actggggtga ttttttcttc aatttcattt
    27901 tttgaaacaa tatttttcaa atagatcatc gccgttttag gatcaactgc gaacttttcg
    27961 aactgcgaac gaaaattttc tgctgtgatg atcacatctg gtttcatgga aactgcggaa
    28021 gaaatatcac aatggtccag tttggcttct actcctaatt tgttcaaaac atcctcagca
    28081 gacatctgtg ctgcaaaact acttcctaaa cctgcgccgc atacgaataa aatgttcaat
    28141 ttgttcatct ttgttctccc ccgtatcatt tattatttct caactactga aaaaagcagt
    28201 tgtttgaaat cttcgatatt tgtgcattca atcaatcgat ccaacttctc ttcgttgttg
    28261 atcaattcaa ttagttcttt catgatgttc agatgggagt aggagtctac tgctgccaaa
    28321 caaaaaataa tctttactgg atccatttca ggattaccga aatcgattgg ttgctcaatc
    28381 gtagctacgc tgactcctaa tttattgacc ccatcttctg gtcgggcatg ggctagtgcc
    28441 atgtgtttgc caatcacgat atacggtccg taatcattca ctgcacgaat catcgcttcg
    28501 acatagcgct cttcgacaat gttttcttta accaatggtc tagcagctag ttcaatcgat
    28561 tcctcccaag tagtggcttt ttctttgatc atgatattgc tgtccgtcaa aatatctttt
    28621 aacataggct ggatctccct tttgttgatt tctaaattgt ttgtttcgaa taatttttct
    28681 aacttgccat agatgattcg atctactcgg ccaccacttt ctttcatgac atctattatt
    28741 tgagtgaata actccgtcga ttcatgactg ttaggctcta accgctgtag ttcttcattt
    28801 cttttcaaaa agtcttctat aaccaagata ttcgtctcag ttaaaatcgg atcgacaact
    28861 aaaagcggct tatttcgata attcaattga aaggtgctga aaaccagatt gacatccaat
    28921 ttatctacta attcgatttc ttttgaactt aaaactgcag taatctcgat ctgaggaaac
    28981 ttttctttca gattctctgc taacagattt ccagtagcca tcccatggtt acagacaacg
    29041 actgatttat aaacataatt caagtctcgc ttgattacac tggcgatcgt cgaaaagtgg
    29101 atgacaagaa aagctatctc gtcctccagt atcttgccac caattacttc ttcgatcgta
    29161 ggaacaaaat gagtgactgc gcggtagatt gggaaataat ttgttcggat gttttctttc
    29221 aatggattca tgacttggat atgattcttg attcttacaa tcagtgcagc catgtgctta
    29281 tagagatttt cgaataaggc ttcttccttt agatggaaag gtacgtgtgt ctcgttctct
    29341 acaaattgga tcaattggat cgttagtaat tgagcttgta cccactcgat tgaattggag
    29401 atatctctag cattgaacgt ctcaatagtg aaacgaagat aatttctttc tacttgcggg
    29461 acattgtcca attgaaattc ctcgatcatg tggtcaataa atgcagaaaa gctactgtct
    29521 tttatttctg tatttttcca attaatggca gagataaatt catgtttcct gattcgctgg
    29581 atccagatca atgtaaaaag caggatttgt tttttataaa tatcatcttc ttgtttcaac
    29641 aacttattgg aatagatctc ctgtattttt ttgatttcct ccaaaggaaa ataatggaga
    29701 aagatttttt gagccggtgt taattgtgca tcttgattca taaagaagtc ggtcattccc
    29761 agattctgat tgataaaatc atagatcatc gtacggatag atcgttctga acctttataa
    29821 accagtcctt gctttccata actgacgatc tctatcccat aactgaccag tgttgctcgt
    29881 aaccgtctca tatcttcatc taatgtactt ttagagattt gaaattcttc ttcttttttg
    29941 tttagatgga tcgggattcg gctgtaagca acggctaaaa ctagatcaaa aatacgttcg
    30001 cgccgattca aaaagccgtc tttcacatct tttatttcag tttctaatcg agcttgcttt
    30061 tccttttcca gcttcaacaa aaaacctttg ttgcgaattg tacggatctc cggaagcttt
    30121 ttactgctca accagatatt cgcttcaaga acttcctgac gaatcgtccg ctgactgaca
    30181 ttgaactcac ttgctagatg ttttgctttt actggatatt gggctgtcat gattctgtga
    30241 agtatttcaa ttgttcttgt tttcatagaa atgatctcct tctgatttca agtatatggt
    30301 tccgcttaca taataaaaag tagatatttc tgccacttga agtggaaaga aagtaagcaa
    30361 agcaaacaaa aaataagcca tatgcttttt catctcctca acgaaaaaga catacgccta
    30421 ttattacaaa aattttgccc atctatacaa aaaagaggtt gtgaaaaagc tgtcctgcat
    30481 caagtaataa gaacaactaa actaaaatag tgcttcctat tttttgtttg gttgttctta
    30541 ttatcgcaga tgcaagcttt taaacaccat ttagtggaga agctgtgaca gagatgttca
    30601 gccttgagcg ataagaagcg attttgaaaa atcgcttccc atattttaca aaatcgtgcc
    30661 ttattgccga taggctatct ctggaacacc gtttattcag aaaaaggagc tgcgacaagg
    30721 cttttgtcac aactccgttc ataaatattt cctgtcaatc cagcataatc ggttgaataa
    30781 aatcggcttg ccatcttttt tctttctcag aaaaatcaaa ataccatatc tgagaaaaat
    30841 actgtcgttg tgtcttactt cctgagatca atcgcccatc ttttcgatcg actgaataat
    30901 cacagcatct gaaatcaatt cggatggcaa aactattttc gtggatctgt cgataatttc
    30961 ctacttcctg aatagttatt tttttagtat gatttcttac accgtctgct ttgttttttt
    31021 gcagaacttt ctgatgttcg gcaaacagct tgtctgtata acagcttctg gctttttcag
    31081 gagtttcttc ttcccaagcg gattggatct tcatgaatat cttttggatt tccaaaaact
    31141 gtgctttctt ttctttagcc gttcctgaca tgcgggacaa tatctccgat ttcagccttt
    31201 tcttttgtct tttattcttg acgatagaaa aagcagaaac ccctcctact gacaaaacag
    31261 ctaatgcaag aaaccccgtt tgctcataac tagaaggacc tgtacttgga ccataatacc
    31321 cataagaatc tctgccgtaa gaacgactgc caaaataact gcccccatat gaacgaccgc
    31381 caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc tccaccatga ccacccgcga
    31441 cagcgaatcc ttgggtcggc agagcaaaca aacataggcc cactaacaaa atgattgcta
    31501 aataattgat tttttcattg tcttcctcgt tatcttttat tacaaaaaac tatttttatc
    31561 atagccttgc taaaaggaag agtcaataac cagatgcata aactgttttt ttagcaattt
    31621 tgtcttattt agtcattgag taacatcgga cagatgtatg tgtcggcagt ccataattcc
    31681 tctatcttca gcatgaacaa gcttgcagac aagagatctg cgcttcctcc aggagagatt
    31741 tggttttcct gacaaaagtg caacagtgct gtaaatggac gatttggtaa agcactttga
    31801 ctagcagcat gagcaagttt ttgcatttcc actaacgttt tctgatcact gcgatgcaat
    31861 acgcatgtgt catctagcga actcatcaaa actaacaaca tatgcatttg tttctgtaca
    31921 tatgaatcat tatctagctc cttagctgct tggattgcaa gcctgatatg cggataccct
    31981 aatatcgctt cttcatatgc accatttacg ccatattttt gcttcaccct atgaccatga
    32041 gtggtttttt tatgacgata ttttgtatca ggaaaagcag caagcttgct gacatcatca
    32101 agtattttcg ataaagaaaa aggctgttcc atactgattt tttgtgcaat gacactgatc
    32161 aatagcccca ttgcccaaat cgctccttta tgggtattga tgccatttgt agcaatcagc
    32221 attgcctttt ccgcttttcg cccaatctca gcaattcttt ctcttaactc ctgatcaata
    32281 gcataatgcc atgctatttg agccatttct tcaaaaaaag gagttagcgt cttagcagac
    32341 ttatccaaaa tgcgccgacc ttcttttacg gcttttgcga tcgtatggaa attatcatct
    32401 cctaaaacca tatcagctgc ctgtttgctt acttcactac ctttgattcc catagcgatt
    32461 cctatatcgg ctcttttcaa agcaggtgca tcatttacgc cgtctccggt cattccgacg
    32521 atttctccat ttttctgcaa agctttcacg attcgcagtt tgtgttctgg tgtcgttcga
    32581 gcaaagacgt cgacttttgg tacttgtcga atcaactctt cttcagacat aagatccaaa
    32641 tcgatccctt ctaaaacttt agcagtatgt tttaagccaa tttgttccgc gatcgctttt
    32701 gctgtatctt tgtgatcccc cgtaatcatt ttcactgaga ttcctgcttg ttggcattcc
    32761 tttacagctt tgactgcact ttcttttggc ggatcaatca acccagcaat ccctgcaaaa
    32821 gttaattggg ttaaagactc atgcgtgagt tcctgtttcg aatctacttt tttgtaagca
    32881 aatcctaaaa cacgctgacc ttttttcgca aacgctgtgg ctgtttgacc ccatgcttct
    32941 tattctgaag aagaaagagt tgatttagcc aataatactt ctggcgcacc tttgacgtaa
    33001 atcacccctc ctttttcctc cgcatgcatc gttgccatat atttgtattc agagctgaac
    33061 ggaatttttg cttctatttt tttcaaaggc agatcggctg tttcggtgtg gcgaatcagt
    33121 gcaagttctg tcggattgcc acttaaattt tctgttttct gttcttcttt cgtctttaat
    33181 tcctgacaat ttttcataat aaacagtacg cgagtttctt cctttgctgc tacatccaca
    33241 actgtcattt cattttttgt caatgtccct gtcttatctg aacagatcac tgtcatagaa
    33301 cctaatgttt ctacagaagg cagtcctttg atgatcgcct tttcttttgc catttcatgt
    33361 actccgacag ataggatcat ggtcaacaca gctggcaatc cttcgggtac cattgacacc
    33421 accaaagcga tcatagctga aagaaggata tgccaatcca tgccatagcg gaatgttgta
    33481 aaaacaacta agaacaagat caaacaaaga atgccttgaa aaatttgttt gttcaatcgg
    33541 ttgatcttct tgatcagagg cgtcgtttgt tgttcgaccg attgcagtgc ttgattgatt
    33601 ttaccgattt ctgtcgtgtt tcctgtttct acaacgacac cgactgcaga accagattgt
    33661 acaagcgttc ctgaaaaagc catatttttt tggtcaccga ttgattcttc tgctgccaaa
    33721 acggaatgat ttttttcaga tgcttctgat tctcccgtca aaatcgattc ttctactagt
    33781 agatcatgta cttcgatcaa ccgaacatct gctggaacga cgtctccggc acgtaagaca
    33841 atgacatctc cttttactag ttctttcgca gggatttttt cttgcatccc gttcgatagt
    33901 actatcgctt cttgtcccat cagctgcttc aaaccattca acgattcttc tgcttttctt
    33961 tcttgccaat aactaacgag tccgttgacg atcactacga ataaaataat acttccttcg
    34021 atgtattcgc tcgaagcaaa tttcaaaaaa gaggcaatga tcaacacgat catcagcaga
    34081 tcagtaaagt gttttgctat ttttttccat cgttttgtct gctgtcttgc ttctatctca
    34141 ttatatcctt gatcagtcag gcgtttctgc cgttcttctt gcgacaagcc ttctgttgat
    34201 gtttgatagt ttttcaatac atcttctacc gtcaatctgt accagttcat cctatcccct
    34261 cctgtttaat tgatactgtt attatacgca gggaagtttt ttcaggcgta tcgattattt
    34321 caggggggtc tgaaataatt cgttttgcag aatgtatctg ggcctaactg atatttctat
    34381 tgcttattct tttatataca aaatttaaga atacaaacca gataaccaat aaaaaaggaa
    34441 taaagcgtgt cgtgctttcg aataacaagc tgaaagcaat tgaagtaaaa aacaccaaca
    34501 aagcaagatc tttatatctt tgtgtagtgt tccgtttctt ttctttaata aattgaacat
    34561 gtgcacacaa gatcgaagac cacacaaata gaaaacaact cgttgtcatg cctgccaaaa
    34621 gctgaaaaaa caatcgacta tcagctacaa aaaaatgtag acaaagaccg acaaaaaata
    34681 acatccctgt aattaaaata ccgtgtaaag gtacgccttt cttagaaagc gcacaaaacc
    34741 aatggggcaa acttttctct tttgctgttt gatataaaat cctgctagta ctgtagactg
    34801 cactatttgc tgaggacaaa gaagcaacca aaatcattag attgacaatt gctgctccgc
    34861 tttggcaatg gatcacttgc agcatagtca ctaaaggact ttcttttaaa tctaaacaat
    34921 gccatggaac aacaaataaa atcgacaaaa tcgttcctat atagaaaaag aggatacgcc
    34981 aaggcagaca gttgattgca tttttcaaat tcttttgtgg gtcactcgtc tcaccaactg
    35041 ttaatccgat catttcaatt ccagcaaaac tgaataaaac cataggaaat gaagcaatca
    35101 ttccagcaaa gccaaacggg actaattcat tgagctgtcc aaaatttgct ttgattccaa
    35161 tagactgggt atgaaaatct gagacactca atcctatacc caataagata aaaaggaaaa
    35221 tccccaagat cttgatgatt gagaaaaaag attccaattc accaaaccac ttgactgcaa
    35281 caaggttgac tgccattaag atcattagtg cgctacctcc gcttatcaaa gctggtacat
    35341 gtacaaacca gaaatggata tacaatccta ttgctgttaa ttccgcaagt ccagctccaa
    35401 gccagcaaag ccaataagtc caattgacaa aaaatgccca ctttttgcct aaataatagt
    35461 caacgaaatc actgatagag ttaaatgtac tatttgctaa aaataaatca cccatgaccc
    35521 gcatcaaacc ataaatagcc aaaccgcata tcaaataaac gagaataaca gctggccctg
    35581 ctgatgcaat tgcctttgct gaacctaaaa ataatcctgt tccaattgcg ccacctaatg
    35641 cgattaactg gatatttcga ttagttagag tccgtttcat tgccggtttt tccatcaagt
    35701 tcaccttttt ctttttcaag cagcatggcg acttcctgtt cccaagaagg tttctttatt
    35761 ttttcaatac agagtggtac tacaaacaaa atgacactga tggctgtgac tgcaattaga
    35821 ttgatccatg tcccagcttt catcgtcagt ccgacagaaa atccgattgc cgcaaataaa
    35881 acaataacga cagtccaaac tccaagattg ctctttttct ctttttttcc aattctaaat
    35941 ggtcgattca actttgcatg tgtataacgc aatctcaaaa ctgcgatccc catgatgaca
    36001 tagacgatac agtagataac agtagttgaa tttacgagca tcaaaaatgc ttgattgacg
    36061 ccaggaatca gcaaataaaa aagtgcaaag attgagataa tgacagactg agtcaaaata
    36121 acggatttgg atacgtcaaa ttgattcgtc ttccaaaaat tgaattttgg tggatacgca
    36181 ccttttctag cactttctgt cactgtcttt gctggtcctg aggcccaagc agataattgg
    36241 actgctacac caatgaagac aagtaaacta aacagattca caataagatg tggcaaacca
    36301 agaatttggc aataaatcga aatagattgc gcgatattat tcaattccat ttgtcctttt
    36361 ggtacgacat ttgctacaac taaagcattc aaaatattga cgaaaaatat aaaaattaac
    36421 gcggcaaata ctccgcgaat atacgtttta actggatttt tcaaccgagt gatatacaca
    36481 gaggacattt cgataccagt aaaaataaac atgatcggcg caaaataaac aaatgaggat
    36541 gcagtcgtag tatctggtat taatttgtcc catgaaaaac tgcctaatgt tccggttggt
    36601 acgatcccaa ctttgatcca cgcagcaaac cctaataaga gcatcatcgt caaaggcacg
    36661 tacaatccta accaaacacc gacttttccg ccgatttttg ccatatcaaa tttcaaattc
    36721 aaaaaagtga tgatccaata aacgactaaa atgacaacta atgtaaattt gctgttcaaa
    36781 ccaagcggca cattatcgat aatattacca aacaacggag caagtgctga agcgaccatc
    36841 accatcccag gaaacatttg gacccataac agccatgaga caacgaaccc ccattttttt
    36901 cctagagcat tcgataccca aagttctgga ccaccttttt ggggaaacat tccggcaaat
    36961 tcaccagaga tcaatgagat tggaaaagcg tacaataata ctgcaaccag catgtaaaaa
    37021 atcatcgtcc agctcgttgc tgctacatct ggaatatttc gtacacttgc tacaagggcg
    37081 caggtcattc cgataaaggt catggtcgtg atttgctttg atgaaccagt atctttcatc
    37141 tttattcctt ctttcaatag cgacatatgt ttttgttttc ttttattttt gttcaagaac
    37201 agaaatgaca aggtttcatc gattcagtac aaaacccagt atcaccgaaa catccattga
    37261 acgatcttag tgaactgggt ttgatacatg aaacgaacga tccaacttat agaacgtttt
    37321 ataaaaaaga atatcttggc gaggaatata tgaaaaacag ggggaaatac aattgttttg
    37381 atgaagcaaa taattgtctg ttctccatat gtctcttgtt attctttcac acaaaaatca
    37441 gttctattgg atgatttcgt ttagtttctt ttccattgct ttggcgattt cttttgtata
    37501 aaaattgaaa attcgatcat cattcaaata aggagtcatg atagccgcac gtagcagagt
    37561 gattttctgt tcttttttcc attcttcttt cgttagaccc attctttcaa caaaacgaat
    37621 cggagaatca ccgtaatctt cttgtgtaaa tgtagtatga gaagtaataa accgttcacc
    37681 ataaacatcg ccatccatat aagaagaccg atcgaacatt ttttcattta attcattgat
    37741 agcgttcaaa tctgtacagc cttgttcttt gaatacccaa ttgaccatat taaaatcagg
    37801 atgattcaat ggatagactt cgattgtttt tcctttaaca gtaaaagtca gatgatcgag
    37861 aaattctctg aatctttgag ctgcctcgat tgaagcccca atcaattgac catatccggt
    37921 cacattcaat ggcaatacac gatgtgctgt ccagactgcg gcggcggttg ctccagcttt
    37981 tgatccttcc aaaatataag ctcctaacat atctggagcc tttactgatt tttcaaacac
    38041 atatggcgcg aaataagaaa tgatatttct catattttta tgtttgatta cgattcctcc
    38101 agcagcataa gggacatagc ccatcttatg aggatctatc gtgacagaat ccgcttctga
    38161 aatagctctg aacccttcat atacctcttt gtcaatcgtt acgcagtggt ggaaaacatg
    38221 atgttcttca aagaattcag ctaaggaagc atacggcaca aattctcctg cttcgtttag
    38281 aaacagtgaa cgcgcatagc cgccatatgc ggcatcaaca tgtaaataga aatagatccc
    38341 ttcatctttt aacctttctc ttaattggac gattttatct acactgtcta cttgaccttc
    38401 ttctgtcgtt cctacgacag caaccacacc tagaattggg attttttgtc cagctaattc
    38461 acgaattgtt ttttccaaag cattaatatc cattcgataa tcctcttgaa ctgggatagc
    38521 aaccatctga tctaagccga ctccgcaaat atctaacgcc ttcatccaag aatagtgttt
    38581 tgtttgaggg accagccatt tccctaatct ttggatattt tttccgctac gggaagaagc
    38641 tgctttgacc tcatccattt cttcgtccgt aaagctttcg gtcatttcca aaatttcttc
    38701 aacagataaa ttcaaaagtt cccactcaga catttttttc actttttcag gcagcacttc
    38761 cttgacagct aaaggaatcg atttgatgca acgggcgtac cataatcctt caagattagc
    38821 aatagaacca tctgctgcaa tgtgtcccca tccgtctgtc atattgaata atgaagcaaa
    38881 atcctgtcct acttctgctt ccatttgcga agttgccata gaagattcca atgcaacatt
    38941 atttgggttc cacagcatcg catagttgta agctaataaa gcaggcatca atgtttcagc
    39001 attcatttgt ccccagtaac ggcctgctga atgccatggg atcgatcctg cgcgtaatcg
    39061 ctgactgact tcatccaaga cctctatcat atggtcgcgg gtggctagat aatctggagt
    39121 gagcttatct ccttcgctaa ttgcaggcat atctgaagga atataatttt ctctccatcc
    39181 aagatgttca tctaccatct tgttcaacaa cattttataa actggtccat tttcagcttt
    39241 gtcgcctata aagacggcct tgatatccat atctttcatt tttcttccct ccatattttg
    39301 ttggtcaatg tcttgcagat acatgtgttt atctgtaaca cctcttcact atagcgccaa
    39361 aaatgagaat ttttttttta taacatcaaa tccacgtaga tttttacaaa caaaaataaa
    39421 taaagtcgga tttttctgat aattcaacgc aaaaaagcga acaatttttc aataaatcag
    39481 tcttctaaaa tagataacct aaaaaaagcg aacaaacaaa taaaatgact gtccttcatt
    39541 cactaaacat atttttattt ttttatattg ttaaaaattc gcaatttatt ttttaataga
    39601 attatctgtt ttccaaattt tataacataa aaaacctttt ttaacggcat ttatatgctt
    39661 tttcagaaat taactgatga tttcaaaaag aaaacatgtc ataatatttc ccatattgtg
    39721 caaaaaaata caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt
    39781 aagacagctg tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct
    39841 ctccaatctc ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa
    39901 agaatttgaa gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt
    39961 ttcagaacat atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt
    40021 aaaaacttgt ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg
    40081 tgaattcatc tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa
    40141 tgactgcggg atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct
    40201 gctgcttctt aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc
    40261 gttttttgaa cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta
    40321 tgataaagaa aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca
    40381 agtgtgtgct gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta
    40441 caattatgtc gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga
    40501 attcgccttt attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt
    40561 gattgcggaa gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa
    40621 agaactagtt gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt
    40681 cgaacgtgcg ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc
    40741 agaaaaattt tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat
    40801 tttttccagc tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg
    40861 ggcttttgtg atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta
    40921 tatcgtcaca aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac
    40981 tactttcgat tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta
    41041 tgcgcagcag tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt
    41101 ccaatatgaa aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc
    41161 tgtgcaaaac aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag
    41221 atgcccattt ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg
    41281 acatctacgg gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc
    41341 aacgccgcta gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca
    41401 gctgaaacaa gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca
    41461 ttgttctcgc tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa
    41521 tccttgattg atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc
    41581 agtacaagtt tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct
    41641 ctcctcttct ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg
    41701 ttcgaatgat aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg
    41761 actcgatgat atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca
    41821 gttttcttgt atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc
    41881 aatcaaaaag tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa
    41941 tatttaaaat agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg
    42001 ctacctactt tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc
    42061 gtctatttaa aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc
    42121 catttttctc cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa
    42181 taaggcttag tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc
    42241 caaatttcta aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt
    42301 tttatttaca ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg
    42361 tcctatcatt tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa
    42421 ggaggcgttt ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc
    42481 ccttggcgct gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata
    42541 tgatgaattc gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa
    42601 gacattggag gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc
    42661 aatatggcag cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc
    42721 ttttattcat tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat
    42781 gaatattgga ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt
    42841 cgcatgctta attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct
    42901 gttactgagc cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga
    42961 acctttgaca aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg
    43021 ggattcaata ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa
    43081 gaagaaaaac tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt
    43141 gaaacaaact tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct
    43201 caagaattgc gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta
    43261 gtgggcgtca atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag
    43321 tacttgaaag aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc
    43381 aaagaaacac cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg
    43441 actcaagaag aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg
    43501 tccattacag attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat
    43561 tatggtgcag cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat
    43621 cctgacaaat tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg
    43681 aaaaaccatt tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc
    43741 ttgaattcat ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg
    43801 tctattgtcg tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt
    43861 tggggttatt tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa
    43921 atgaatggaa aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga
    43981 ccagtgaata ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct
    44041 gtctatatgc cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa
    44101 gtcattccta aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat
    44161 cagatgatct ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt
    44221 gcgggtattc ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact
    44281 ctagctcgtg ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg
    44341 catcaagtaa taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac
    44401 ttattaccgc agatgcaagc ttttgaacac cgtttaccaa gaggttatga aaaagctgcc
    44461 ctgcatcaag taataagagc agccaagcta aaacagcttc ttatgttttt gacttggtta
    44521 gacttattac cgcagatgca agcttttgaa caccgtttac caagaggtta tgaaaaaggc
    44581 gtttagtttc gagtatgaag aaaaattttg tgaaaatggt tcctcacgtt tttgcataaa
    44641 tttgacttaa taccgagaaa ctgatccctt ctgtcataac ctctttttat ttatgtctgt
    44701 ttctttttga aaacaactat tttttcaacg tttactctct tgccaatcca acatcatcta
    44761 acggatacaa ctatttcaat gattaccatt acactaaaaa atcggaaaca cacctctccg
    44821 aacacaaata cataagacta tagaatgttt catttaagaa aaaaagcgtt tcattatcaa
    44881 aaaggtaaga tctcctttaa aatgaaatta tctgtagtac taataatgca gacaatttta
    44941 tgaatctgaa aggagcatct ccaatgaaag cagtcacttg gcaaggaaaa cagaaaatgg
    45001 aaatcagaaa cgtagatgat ccaaaaatat tagaaccaac agatgcaatc atccgtatca
    45061 cagcaacagc catttgcggc tccgatctgc atctttacca tcatggtgaa gcagttttgg
    45121 aaaaagggta tgttgtagga cacgaaccaa tgggaatcgt tgaagaagtg ggatctcaag
    45181 ttcaaacatt gaaaaaaggg caacgtgtgg ttatcccttt taatattagt tgtggtcatt
    45241 gtcatttctg cctgaatcac atggaaagcc aatgtgatga atcaaatcca gatcagttat
    45301 atggcgggct tttcggattt ggcaagttga acggtaatca ttggggtggt caagcggaat
    45361 atctaagagt tccttatgca gactctactt catttgttgt accagataat gatcttcctg
    45421 atgaaaaagt tttatttcta tcagatattt tgcccacagc ttattggagc gttgaaaacg
    45481 caggagtaaa aaaaggcgat acagttgtga ttctaggttc tggtccagtc ggtctattcg
    45541 ctcaaaaatt cgctgttatg gctggagcag agcgcgtaat cgcagtagat ccagtacagc
    45601 accgtctaga taaagcggct aattacaatg gggttgaaac ttatttctta gaagacacgg
    45661 cacaagctgg aacagaattg tatgaactgg ctaaaggtgg cgcagatgtc attatcgatt
    45721 gtgtaggaat ggacggatta gagcctgtca aagaaaaagc gaaaaattta gtaagcttac
    45781 aaagcggcac aatctctcca ttacagatgg catcgcaagc tgtcaaaaaa tttggaacag
    45841 tccaagtaac tggtgtttat atgactccag cttcttctta cccgctgcaa gaatttttta
    45901 tgcgggatat cgctgtcaag catggacagg caccaattat ccatctaatg ccaaaaattt
    45961 acgcaatgat tgcagaagga ctattcgatc ctacacaaat cattactcat tcgctgccac
    46021 tatcagaagc agcacaagca tatgagatct ttgacaaaaa agaagataaa aatataaaag
    46081 ttgttttgaa accttgaatt cagtaaaaaa tacaggtgat tttctttatg cccaaaatca
    46141 aacgaaatac ccatgagatc gaaataggaa aagaagaaga tatcgaaata cgaggacgtc
    46201 gcttccgctt ctatttccaa aatcgttaca cattgatctc actggctgtc gatttattaa
    46261 ccgggatttt ctatattttt ggaagccttg cttccttaac taaaatcccc gatcgatatg
    46321 gcacctattt ttatttggct ggtgctattt tcttgacgat tcgtcctatt ctcagaatcg
    46381 taaggaacat ttttatttac gacgaaaaaa aagcaatgaa gagaacaagc aaaaaaaaag
    46441 aggcatgaga atttttcaaa tctcatgcct cttttttcac cctatcgtat cactttgata
    46501 cagacgagcg gtcgtcccac tttcttcctt gaccattgtc aaaaatgtcc actcgtatcg
    46561 ttcataaaac gtggtatgat ctgtaattaa gtaaagtttt tcgtacccaa gttgatgcat
    46621 ttcttttctg atttccgcta atatccgctt ggctatcccc tgcttacgct tttccggttc
    46681 aacaaacagg gcacaaagat ttggtgtcag atcagggcgg ttatggaagt cgttttcaat
    46741 gacgcccgct cctccgacga tggtttcttt ttcatctaag accacatacc attgaggaat
    46801 actttcctta ttagcgattc cagtacgaat actttcctca tacacaacag caggaactcc
    46861 ccattttgat gaaaaccaat tcgcgctttg ttttactaat tctgggtgtt ctcttaattt
    46921 gatccagtta tatgtaacca atgtttaaac ctccgactaa aataaaacgt ttacaaaaat
    46981 tatacaagtc tttatgaaaa ttagcaatga caacaatagt gatgtaaaaa aaaaaacgga
    47041 aaacaatcac ttgttctccg ttttttgatt aatcaagcat ctaaagcttc ttttcttctt
    47101 tcttggatcg tagctacctt gacgaacggt agatagatca aaatagaaag aaccaaattg
    47161 acagcggcta gtacaccacc tgcaatactt tttgttgcca atacaccgcc aataattggt
    47221 ggagttaccc atggaggcat aacggtagct gctggcacta aacctgtaga agtcgcaaag
    47281 taagcaacac taac
//
LOCUS       DAFEML010000018        44490 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFEML010000018
VERSION     DAFEML010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.018"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..1152
                     /locus_tag="LP468_001128"
     CDS             <1..1152
                     /locus_tag="LP468_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBL2080678.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="LP468_001129"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="LP468_001129"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL2080679.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSMTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="LP468_001130"
     CDS             2728..3003
                     /locus_tag="LP468_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBL2080680.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="LP468_001131"
     CDS             3009..3776
                     /locus_tag="LP468_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL2080681.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="LP468_001132"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="LP468_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL2080682.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGIIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="LP468_001133"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="LP468_001133"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL2080683.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="LP468_001134"
     CDS             7920..8222
                     /locus_tag="LP468_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL2080684.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="LP468_001135"
     CDS             8225..9388
                     /locus_tag="LP468_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2080685.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="LP468_001136"
     CDS             9414..12842
                     /locus_tag="LP468_001136"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL2080686.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="LP468_001137"
     CDS             12863..13987
                     /locus_tag="LP468_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080687.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="LP468_001138"
     CDS             13977..14414
                     /locus_tag="LP468_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2080688.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="LP468_001139"
     CDS             14398..14736
                     /locus_tag="LP468_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL2080689.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="LP468_001140"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="LP468_001140"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL2080690.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="LP468_001141"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="LP468_001141"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL2080691.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="LP468_001142"
     CDS             15893..16936
                     /locus_tag="LP468_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL2080692.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="LP468_001143"
     CDS             17095..17823
                     /locus_tag="LP468_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL2080693.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="LP468_001144"
     CDS             17939..18184
                     /locus_tag="LP468_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2080694.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="LP468_001145"
     CDS             18181..18399
                     /locus_tag="LP468_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL2080695.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="LP468_001146"
     CDS             18535..19074
                     /locus_tag="LP468_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL2080696.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="LP468_001147"
     CDS             19067..21340
                     /locus_tag="LP468_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL2080697.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="LP468_001148"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="LP468_001148"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL2080698.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="LP468_001149"
     CDS             complement(22513..22767)
                     /locus_tag="LP468_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL2080699.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="LP468_001150"
     CDS             complement(23167..23436)
                     /locus_tag="LP468_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080700.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="LP468_001151"
     CDS             complement(23906..24361)
                     /locus_tag="LP468_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL2080701.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="LP468_001152"
     CDS             complement(24499..26427)
                     /locus_tag="LP468_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2080702.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="LP468_001153"
     CDS             complement(26624..27457)
                     /locus_tag="LP468_001153"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL2080703.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="LP468_001154"
     CDS             complement(27649..28353)
                     /locus_tag="LP468_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2080704.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="LP468_001155"
     CDS             complement(28376..29002)
                     /locus_tag="LP468_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2080705.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="LP468_001156"
     CDS             29328..31703
                     /locus_tag="LP468_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL2080706.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="LP468_001157"
     CDS             complement(31727..32218)
                     /locus_tag="LP468_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL2080707.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="LP468_001158"
     CDS             32405..33325
                     /locus_tag="LP468_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2080708.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="LP468_001159"
     CDS             33479..33823
                     /locus_tag="LP468_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL2080709.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="LP468_001160"
     CDS             complement(34013..34513)
                     /locus_tag="LP468_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080710.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="LP468_001161"
     tRNA            35041..35124
                     /locus_tag="LP468_001161"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..36086)
                     /locus_tag="LP468_001162"
     CDS             complement(35448..36086)
                     /locus_tag="LP468_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2080711.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            36421..36855
                     /locus_tag="LP468_001163"
     CDS             36421..36855
                     /locus_tag="LP468_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2080712.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            36878..37198
                     /locus_tag="LP468_001164"
     CDS             36878..37198
                     /locus_tag="LP468_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080713.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            37339..37530
                     /locus_tag="LP468_001165"
     CDS             37339..37530
                     /locus_tag="LP468_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080714.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(37601..37858)
                     /locus_tag="LP468_001166"
     CDS             complement(37601..37858)
                     /locus_tag="LP468_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL2080715.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            38016..38279
                     /locus_tag="LP468_001167"
     CDS             38016..38279
                     /locus_tag="LP468_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080716.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            38303..38491
                     /locus_tag="LP468_001168"
     CDS             38303..38491
                     /locus_tag="LP468_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080717.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(38574..38759)
                     /locus_tag="LP468_001169"
     CDS             complement(38574..38759)
                     /locus_tag="LP468_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080718.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            38974..39345
                     /locus_tag="LP468_001170"
     CDS             38974..39345
                     /locus_tag="LP468_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2080719.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(39495..39567)
                     /locus_tag="LP468_001171"
     tRNA            complement(39495..39567)
                     /locus_tag="LP468_001171"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39532..39534),aa:Gln,seq:ctg)
     gene            complement(39613..40041)
                     /locus_tag="LP468_001172"
     CDS             complement(39613..40041)
                     /locus_tag="LP468_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080720.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(40101..40859)
                     /locus_tag="LP468_001173"
     CDS             complement(40101..40859)
                     /locus_tag="LP468_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL2080721.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            41154..41351
                     /locus_tag="LP468_001174"
     CDS             41154..41351
                     /locus_tag="LP468_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080722.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            41457..41939
                     /locus_tag="LP468_001175"
     CDS             41457..41939
                     /locus_tag="LP468_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080723.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(41997..42593)
                     /locus_tag="LP468_001176"
     CDS             complement(41997..42593)
                     /locus_tag="LP468_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2080724.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            42980..44446
                     /locus_tag="LP468_001177"
     CDS             42980..44446
                     /locus_tag="LP468_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL2080725.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        14691 a         7624 c         9101 g        13074 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagca tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaataatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgttg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 tagatcaggt taatatcaga aattgaattt gattctgcaa tggcattgat caaggagtta
    35941 tcaccaacgt atttttgaga aatcgttgat agagtatcac ctgattgaac ggtataagct
    36001 tcgtccgcat gagcagtcgt tcccatgaag aatgcagcgc cggcagccaa agttgttcca
    36061 aaaagtaaag ttttaagtga tgtcatgaaa aatctccttt attcgttaaa aagttttatt
    36121 tgttgtgttc aacgaggaat actttaacac gtgaaaatat ttcataggta aaagaagcat
    36181 gacaatttat gacaaatcca cgttttttgt aacagaatga tgttcgctcg atgtgaaaaa
    36241 tgatgaggaa tttcacataa tgcagaaata atgggattag aacaggtgtt ctgatgagaa
    36301 aagaaatgta taaataactt gaaagaaatt gcttttgttc atcattttat ttacatattg
    36361 cgtatatttt ttgtattttt gcttgagatg ttacaataaa agaaaaagga ggcggttcca
    36421 atgagtaaaa gataccagaa catcatggta gcagttgacg gatcaagaca atcgatcaaa
    36481 gcgttcgctg aagcccttga cttagcaaag gacaatgaag cccacttatt tatcgtgtca
    36541 atcatcaaca aagttgagct gacccatagt gcctatgcct tttcaaaaat ctatgcagat
    36601 gaaaaacaaa gaacagaagt agccatgctg aaaaaaatca atgatgccaa agagtacggc
    36661 attgctgaga tccacgcaat agttgaaact ggagatccaa gaaatttgat tgccaatgtc
    36721 atccctggac aagaaaatat tgatttgatc gttatgggag cgacaggaaa aggtgctata
    36781 caacaagcat tagttggatc gaccgcttct tatgtcgtat cacatgcccc ttgcagtgtg
    36841 ttggtcgtga agtaatgaga taagggagga atagaaaatg gttcgtcctc aagaagtccg
    36901 tgcgccaaaa gaaaaaatag aaattttagc aattattgaa gacggcacac aaacaaagaa
    36961 gggatactcg atcgctttag taaagtggaa aggaaaaaaa ggtgttgctc tgagatggga
    37021 tggagataac caacaagata aaggattccc tgtcacagct aacggttatc atccagcgtg
    37081 gtttgttctg cctgataaat ttatggaatt atacagctat gattatgcaa gagccgcagc
    37141 atcaatcaaa gcattagata aattaacaga agagcagaat gaaatggagg aaaaataaaa
    37201 aagacgaacc aatcagcctt tagaaaactg attagttcga ggagtaaaaa tgaaaaaagg
    37261 ttatttggga tgaaactaga ataatgcgta taacttaaat aaaacttaaa gcaataaaat
    37321 ggcaagaggg tgaggcaaat ggaagcagga aaagtattac aggaagtaaa agcactatgt
    37381 gcagataaaa aatatgaaga agcgaaaagc ctgatcgaaa agaacaaaga aaatttggaa
    37441 gaaaagtacc cgatcgcaca agaatttata gaattaaaac aaggaacgat ccttcaccga
    37501 ttcaaacatt tttttggtat aacagaatag aaaaaacgat taaagatcgg cagaaatttg
    37561 ctgcatcttt aatcgttttc tttttaaaca tgcgagggat tcaattctga ttcttatata
    37621 aaaaatagat ccaaataata agaaaaatta ctgaaagcgt caattcgatg atgtgtgtta
    37681 ttaatacaga cgttgtttcc caatgcctaa aagaaaaaat ttgataagta aaatatacag
    37741 caggtaaaga ggccagtaaa actgaaaact tcttttttgt ccattttatg taatagaaaa
    37801 gaatgcttat cataataaaa aaaggaatat aaaaaacaaa ttgaccgatc gcgatcatac
    37861 tattgcctcc gataaataaa gtccatgata caaaataaca ctttgtgcga aatggcgcaa
    37921 gcagttttgt ggatttatcc ggtaaaatct gtatcgattt tgaaattaga ggagaaactt
    37981 gctataatca aagtgaaaga aggagtggga ttttcatgga tcatgtagtg ttagaaatcg
    38041 atttgcattt gatcaataat attcgggtga tttactatgt tgtaagtaac agtgtcgaac
    38101 aacgtgtact gacgaataaa ataaatggta ttttagcaaa gaaagacgtt caccgattca
    38161 ataatggtga aggaagttat tatagtatcc cagtagaaaa aattatttat acgacagtca
    38221 aagtcagaga agatctagat accaaaaaag catatgaacc tatttttaca acttattgat
    38281 tgacagcaga tggaggaaaa aaatgaatcc atatgaacaa cttattcaag atttgatcga
    38341 tggaaaaatc gaaaagattg atgtaaaaag agaagaatta atggcttttc gagaagcgtg
    38401 gctgaagttg gagaatcgta aatatgtggt gggaaaagcc tcactgaacg gcaatgtgac
    38461 ttatcattac gatccgacac gtttatttta gtatgaagta ttcagaaaag aaccaaagga
    38521 ggacgatgca gcagcattgt cctcctttga ttttacaaaa gtgaaagttt tacttatttg
    38581 aatagatttt taaatttgtt tttgacactg tcgatattta catcttttaa aagattttgg
    38641 gctttctctt tataaggtcc taattgttct ttatgttctt cgataaatcg ttttgcgcca
    38701 tcgaaattgc cgttcttaat catttccttg actttttgaa ataattcttc ttgattcatt
    38761 ttgaacacat cctttgctat caacatgatt ttttacatgg acaaaacgag aaaaactgat
    38821 ttatccacac gtcaataata tcaaataacg atcattttta ctaaaaaaac actcgattct
    38881 cgcttctaaa gtaggagaaa aatctccaac ttgggacgga tggaatttct ttaactgacc
    38941 catatactga atatataaca aggaggtaga aagatgaaag tgattaaata tttgattgga
    39001 ctggcggcga ttagtggtat tttgctattt ggactgaaat attatactga aggaagttat
    39061 ggagaaatcc ctggtatact tgatcagcta aatccattag ttgaaaaagg agaggtctat
    39121 gtaaagacac aaaaaccaga ggaagtaaat gaatatggta cagcaaggta tgtgcagaaa
    39181 gctgctgatg ccaatgggaa agaacgaacg gttgaattta atggtctttc tgtgttaaaa
    39241 gaaaatcatt atttgaaaat tagcaataaa ggagcacaca tagaaacgta tgaggaagtt
    39301 cctagagaaa aagttccgga gaaagcatta gcaattattg ggtaaatcag tttttgtatt
    39361 aagaatacgc ccgattttat tattcataat ttaattatgt aaactaaata caagtagtaa
    39421 aaataataca ataatccccc tgcaaaaaga ttgttctttt acagggggtt cattttttca
    39481 gcaagcacat caaattggga tggcagggtt cgaacctaca attgcttgat tcagagtcaa
    39541 gtgccttacc agtttggcta catcccattt attcaacaaa ataatcatag cactttccta
    39601 aaaaaacgca agttattttt cttgatcgga tagttgttgc tttactcgta aaaggcggcg
    39661 tactagtttc ttttctaatc cagcaggaag ggcaatcagt tctgctactg acaagacggt
    39721 gtccaataac tgatattctt tgacaggttc attcataata tgatagatgt ttgctaaacg
    39781 ttcaatatat tcaaagcgag tatactctgt tcgagcaatt agaaatttca ataaatcggt
    39841 ggctttctcg tactcttgat ctgcgtaata aacaagagat tgacgataca atttgatttc
    39901 cagttcattg agggtagcag gtctgcgacg ctcgttccac tcattaatag agactttacc
    39961 ttgaacattt cccttgcagt cacggacaaa aataatcgga atttcatttg gatccatttt
    40021 tttatgtgtg aatttttcca ttatctacgc tcccttcaaa ggtttggtat cttgagtata
    40081 agggattttt gtttgaatta ctagcttttc tccaaagtta gcatctgtcc acccattgca
    40141 gtgaaaatcg ccgaaaaatc gttgatcggt actgctcgat tttttacacc atagggatcg
    40201 ttgacataaa tattttcttt gtcatatcca gtgactacac aagcatgaac aagaggagtg
    40261 actcttactt ctccattatt tgtggtccaa gtcataaaat cagtttcatc tgggacttca
    40321 aaattgatag tcacagaagt ccagacagga tttcctttag atagtgcttt tttgatatca
    40381 tcgagttgag catcggtttt tggaaaagtg tgataatccg tttggacgat ttgctgagca
    40441 agggaggcaa ctgggggaac atagacgacc atagcccagt ctccgccact gatatcacca
    40501 acaaatcctt cattaggatc gccatgagtc ccatctgcat tgaaaacagg gacgtaatcc
    40561 aattgctcag ctaactggtt tttagttgtt tcataaccat aaaaagataa aagcatagaa
    40621 agcgaagtga cttcacagcc attttctaaa gaaggagaat caaactggct ctctaatgga
    40681 acatctagta aaacttctgc tttctctttt gtctttttcg ttttttgtgt tgaacttttt
    40741 tgtgcagtgt tcattgtatg ttctggagaa tggatatgta ggtaataact tgtaccgctt
    40801 aataaaagag cagctgtgcc ccctagaaac aatagttttt tgaacgtttt tttcttcatt
    40861 tgaaatctcc cttttcagct gtttatcttt cctattataa atgtattttt attggaaatg
    40921 gaagtattat attttaatat gtaggaaata attagttttt aaggaatatg ttttaatttt
    40981 ttgaaaaaaa ttcttctaaa tacaacagct gttttaattg tgaaaacgaa aacagtacgc
    41041 tataatgcct gtaaggttga tttttaactg taaataaaaa tcaatgagtt aaatctccaa
    41101 agaaatagca gtggtaatgt ggagaaaagt tccagcagtt taggaggatt ttgatgacgg
    41161 aagaaatgat taatttagga gaacaatatg catgcaaacc aattggtttt acaaaaacgg
    41221 tcattggtga agttgtatca aaaatgacaa actgcgccgt ggtcaaagtt gcccaatgtg
    41281 ctgcagagga ccaagaatta ttagatgaaa aagcaagcat ggttgttgca aaatatgata
    41341 catttgaata aagaaaacaa ttggacgtgc ggcgtgctgc aagtccaatt tctttgagaa
    41401 ggtaaatcag tattcttttc ctattttctg gagaagaaaa agcgaggcga gttgtcatgg
    41461 taacattctt tacggttcta ttgtttttat tcgttgttgt gatgttttta tttctttggc
    41521 tggttcgaaa agaaattatt tatcggactg tgcgaaatcg atgggtctac ttggtgatac
    41581 ccttcttagt gtcactagtc atttggtata cactcatcag tcatcctaca gcagatgaat
    41641 tggcaaaagg gatcttgtca gcaatgattt ttattagttt tttgttggac agtagaggaa
    41701 tcacagaaga aggacttgtt ttgaatagct ttgacaaaaa aggtgttcct ttttctgaga
    41761 tcaataaaat tgtattatat cagccaaaag gttctaaaat cgtaaaaatg aattttttcc
    41821 gaaacggatg gcgaggaccg atgctgaaat tttctgcatc attagaagaa ttagttccat
    41881 ttttgtccca acgcttaaac gatgaggcag agattgatat tatgattgat ccagaataaa
    41941 aacagaggtt gcgacaagat gtttgtcaca acctctgttt tttatttcaa ataaaattat
    42001 ccaaatacgc ggaagcgatc ggcatcgttc atgtattctt tttccccagc cggtgtttct
    42061 ggtgaaccga atactaattg cgaacgtagt ttccagtttg aagggatatt ccattctttt
    42121 gcaactgctt cgtcaataac tgggttgtaa tgttgcaagt ttgcgcccaa tcctttatca
    42181 actaatgcta cccaagtatt agctgttgcg attccgtttg attgttctga ccaatctggg
    42241 aagttgtctg catataattc aaattgttct tgtagacctt ttaccacgtc agtatctttg
    42301 aagaataata ctgtaccata accatttttg aaaccagcta atttgttttg tgtatttggg
    42361 aaagcttctg ctggagtcaa tgggcgaagt gcttcttcag tgatttccca aagtttttca
    42421 tgtgcatctc cgaaaaggat aactgcgcgt gttgattgag cattgaaagc agttgggctt
    42481 tctttaattg cttctttgat caaagttgtt aattcttcat tagaaagtga aacattacgt
    42541 cctagatgat agattgaacg gcggtttttc aaagtgtcag taaaagttgt cataataaaa
    42601 tttctccttt gatttgcgtt ttgcattttt ttaattgatt acgaaatgaa gtatagcacc
    42661 ttacaaaaag taagtaaaca gatatgctca caaaaaataa gcgaagttca aaaaacaatt
    42721 ttaataagaa aaatcgttat gtaaggattt tcttagttat cgctttcatt gttgtgtttt
    42781 aggaattttt gcttatttga aaaaaacagc tgatatataa ttattaaatc tctatcttct
    42841 tttttttatg atattgccat taaaaattac ttgcttttat agaaaattag tttatatttc
    42901 ttaaataagt tttttagtta aatttttcgg taaagatgta taatattttc tgaaaattta
    42961 aagaattggg gtatagatta tggaaaaaca gcaagacaag ggcttcttcg ggcagccgaa
    43021 gggattgtca actttgttct tcactgagat gtgggaacga tttagttatt acggtatgcg
    43081 tgcattactt atctattata tgtacgatac agttgccaac gggggacttg gattaccacg
    43141 agcaacagca ttagctatca tgtcgatcta cggatctttg atctacatgt ctagtatcgt
    43201 cggcggatgg gtatctgacc gagtgttagg agcaaaacgc actgtattct tcggtggagt
    43261 tttcattatg cttggccaca tcgtcttggc tttaccattt ggtgtaagta cattgtttgt
    43321 ttcgatggca ttgattatta tcggaaccgc ctttttgaaa ccaaatgttt ctggcatggt
    43381 cggacatctt tattcaaaga ctgacttgcg aagagatgca ggattttcga ttttttacat
    43441 gggtgtcaac ttaggggcat tattagcacc actaatcgtt ggtacaatcg gtcaagaata
    43501 taactatcat ttagggttct ctttagctgc tattgggatg ttctttggat tattacaata
    43561 catcatccaa ggacgcaaga cattagacgg agtgggtaca acaccgccga atcctttgac
    43621 aactgaagaa cgtaaaggat tcatccgtaa cttgatcatc gcacttgttg ttatcgctgc
    43681 agtattcggc ggggcacaac taactggtca tctgacaatt gacttttttg tcaatacaat
    43741 cagtgtattg gggattatct taccgttgta ttactttatc aaaatgctga cttcaaaaga
    43801 tgtaactgct gaagaaaaac caagagtatg ggcttatatc ccattattcc ttgcagcaat
    43861 cattttctgg tcattacaag aacaaggttc atctatctta gctttatttg ctagtgaacg
    43921 tacacaatct acgctatttg gtgtaacgat ccaagcaagc tggtatcaat cattgaatcc
    43981 aattttcatc tttattctga caccagtatt cgtaacgatg tggacgaaac ttggtgaacg
    44041 tcaaccatct acagtagtga aattctctct tggactttta tttgcaggat tatcgtactt
    44101 gctattgatg ttgccgggta tgctttatgg tacaagtgga aaagtaagtc cattgtggtt
    44161 gttgggaagt ttcttcatcg tggttattgc tgaattgtgt ctttcaccag ttggtttgtc
    44221 tgtgacaaca aaattagcac cacgagcatt tgaatcacaa acaatcgcta tttggttctt
    44281 agctgatgct tcttcacaag caatcaatgc acaaattgca cgcttctaca caccgggaac
    44341 agaatctgct tacttcggta ttatcggtgc agtagcaatc gtcggtggta tcttgctatt
    44401 tactgtgaaa gaaccaatca aaaaactaat gggctctatt cattaatcaa tgaacataaa
    44461 aacaggaatt gcttatttgc agcagttcct
//
LOCUS       DAFEML010000019        35373 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFEML010000019
VERSION     DAFEML010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.019"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(90..1109)
                     /locus_tag="LP468_001178"
     CDS             complement(90..1109)
                     /locus_tag="LP468_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080726.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1131..2138)
                     /locus_tag="LP468_001179"
     CDS             complement(1131..2138)
                     /locus_tag="LP468_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2080727.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2131..2796)
                     /gene="pgmB"
                     /locus_tag="LP468_001180"
     CDS             complement(2131..2796)
                     /gene="pgmB"
                     /locus_tag="LP468_001180"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2080728.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2789..5083)
                     /locus_tag="LP468_001181"
     CDS             complement(2789..5083)
                     /locus_tag="LP468_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2080729.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5343..7508
                     /locus_tag="LP468_001182"
     CDS             5343..7508
                     /locus_tag="LP468_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2080730.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7812..8645
                     /locus_tag="LP468_001183"
     CDS             7812..8645
                     /locus_tag="LP468_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL2080731.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8747..10447)
                     /locus_tag="LP468_001184"
     CDS             complement(8747..10447)
                     /locus_tag="LP468_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080732.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10954..12114
                     /locus_tag="LP468_001185"
     CDS             10954..12114
                     /locus_tag="LP468_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2080733.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12130..12573
                     /locus_tag="LP468_001186"
     CDS             12130..12573
                     /locus_tag="LP468_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080734.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13056..13586)
                     /locus_tag="LP468_001187"
     CDS             complement(13056..13586)
                     /locus_tag="LP468_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL2080735.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13691..14242
                     /locus_tag="LP468_001188"
     CDS             13691..14242
                     /locus_tag="LP468_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2080736.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14395..14868)
                     /locus_tag="LP468_001189"
     CDS             complement(14395..14868)
                     /locus_tag="LP468_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2080737.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15006..16478
                     /locus_tag="LP468_001190"
     CDS             15006..16478
                     /locus_tag="LP468_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2080738.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16475..17185
                     /locus_tag="LP468_001191"
     CDS             16475..17185
                     /locus_tag="LP468_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL2080739.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17537..17821
                     /locus_tag="LP468_001192"
     CDS             17537..17821
                     /locus_tag="LP468_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL2080740.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18102..18521)
                     /locus_tag="LP468_001193"
     CDS             complement(18102..18521)
                     /locus_tag="LP468_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL2080741.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18523..19107)
                     /locus_tag="LP468_001194"
     CDS             complement(18523..19107)
                     /locus_tag="LP468_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL2080742.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19154..20629)
                     /locus_tag="LP468_001195"
     CDS             complement(19154..20629)
                     /locus_tag="LP468_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL2080743.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20810..21121
                     /locus_tag="LP468_001196"
     CDS             20810..21121
                     /locus_tag="LP468_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080744.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21236..23572)
                     /locus_tag="LP468_001197"
     CDS             complement(21236..23572)
                     /locus_tag="LP468_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2080745.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23714..24382
                     /locus_tag="LP468_001198"
     CDS             23714..24382
                     /locus_tag="LP468_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2080746.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24385..25424
                     /locus_tag="LP468_001199"
                     /pseudo
     CDS             24385..25424
                     /locus_tag="LP468_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
     gene            complement(25661..26542)
                     /locus_tag="LP468_001200"
     CDS             complement(25661..26542)
                     /locus_tag="LP468_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2080747.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26701..27429
                     /locus_tag="LP468_001201"
     CDS             26701..27429
                     /locus_tag="LP468_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL2080748.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27585..27902
                     /locus_tag="LP468_001202"
     CDS             27585..27902
                     /locus_tag="LP468_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2080749.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27895..28503
                     /locus_tag="LP468_001203"
     CDS             27895..28503
                     /locus_tag="LP468_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL2080750.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28558..29349
                     /locus_tag="LP468_001204"
     CDS             28558..29349
                     /locus_tag="LP468_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL2080751.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            29487..29999
                     /locus_tag="LP468_001205"
     CDS             29487..29999
                     /locus_tag="LP468_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL2080752.1"
                     /translation="MKVEEGQREKLKTEMERLHIYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            30025..30897
                     /locus_tag="LP468_001206"
     CDS             30025..30897
                     /locus_tag="LP468_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2080753.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31073..31435
                     /locus_tag="LP468_001207"
     CDS             31073..31435
                     /locus_tag="LP468_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2080754.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31444..32196
                     /locus_tag="LP468_001208"
     CDS             31444..32196
                     /locus_tag="LP468_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080755.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVKPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32210..34012
                     /locus_tag="LP468_001209"
     CDS             32210..34012
                     /locus_tag="LP468_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080756.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34289..35329
                     /locus_tag="LP468_001210"
     CDS             34289..35329
                     /locus_tag="LP468_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2080757.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT        11050 a         6252 c         7287 g        10784 t
ORIGIN      
        1 agataaacaa tgtgttagaa gtagtatctt cttttacata aaaagctgac cataggataa
       61 atggtcagcg tatttagtga gtcagctatt tagtatgggt tttctaaagg aacgactgtc
      121 tctcttttga tcaagcgatg agggatgacc aaacgtacgc cactgctcaa ttcttcatgg
      181 atcaattcgc gcagcttttg catagcgaca cgtcctaatt cggagatatc gatatcgata
      241 cttgtaaggt aagggtgtgt taatgttgag aagatcgagt tgttgaagct aatgacggag
      301 agtgtctctg gaatgacata gccatacatt tgcgccaact gcatcgtgcg aagggcgaag
      361 atatcgtcaa tgaccaccaa tgctgtggct tcgttttctt tcaacgtttt ctcaaaggac
      421 agataatcct ccggatgctc tagtactaca ctggataacg caggaagacc agccatcatc
      481 attgcttttt gataaccgaa atatcgttcg aaatacaaac tttcatgagt cgtgtttgtc
      541 acaaacagga tattcttatg tccattctgg atcaaaaatt ctgttgcttg tttacctaga
      601 agctggttat cattatctac ataaacgatt tcgttctcat gatgataagg ctgtccgatc
      661 aaagtgaaag ggatgtggtt ttggtataaa taatcaatga cagtatcttg actatctgaa
      721 tacactagaa taaaaccatc tacttgtttt tgtaaatgca tacgctggac gttctctaac
      781 agcaattcaa aatttttagc agtagcgatt gctgtagtca tatcataatt ccgcgcttct
      841 tcgttgattg cttccatgat ctcaagataa aatgggttac cgatccgctc ttttgaatca
      901 agagggggta agattacgcc gatggcactg gaaatgcgtt ttcctagatt gcgggcagtc
      961 atgttaggaa cataacctag ttcatccata atttttcgga ctttcttctt tgttgtctcg
     1021 gaaatactag gatgatcgtt gatgacacga gagacggtcg aggtggcaac accggctttt
     1081 ttcgccacat cttttacggt aatagccatg ataaaaacac ctttctcttg ttattgtgca
     1141 gagaaccgat aaatcgtctg actgatccgt tcttgaccag gatggaggtt gatcgatcca
     1201 aatttgggga aatgaacgat atcagggatt tcttgcggtt cgattgctaa tccgtagttt
     1261 gaatgcatct gttttccatt gacagagaaa tcagcttcga atccagtcgt agaaaataat
     1321 accatacttt tattagaagt tgctatagtc atttggcgac cagaatgctt ctcgaataat
     1381 tgtaaggaag ttttggaaag cctaggatga tgcaaaagaa atacatcatc tagtccatct
     1441 ggataacatg caaggatctc ttgcagtgtt ggggattttc taaagtcgat tggcagtttt
     1501 tctttttttg tccaatttcc agtaggcagt ttttcttgat ctaattcaag cacaccatct
     1561 aaaaagaccg ttaactgatg ttcatagatg tctcttgttc catttcctga aaggttgaag
     1621 taggcatggt tggtcggatt gcagatggtt tcaacaaggc tactagcaga ggttgtcatc
     1681 tctaattcgt tttttgttaa acggtaagtg atcgtagcag tgattggtcc tggataggta
     1741 gaaaattcat cttttaagta aaagaccaca cctattgatg atggagtttt gaaaacttct
     1801 acttcccaaa attggaaaga ccagcctttc gtgccaccgt ggatatggtg tgatccgcag
     1861 tttttctcca atctatgctc accccaagaa gcatcccgga tccttccggc tacaggtccg
     1921 acagttgctc caaaaaagct tttgtctgtt agaacatctt cgaaacgatc gtaagacaat
     1981 aaaacatttt ctgattttcc ttctttgtct ggtgcgaaga tttggtgcag gcgggcaccg
     2041 taattgagaa gaacgacttc taagtagtcg ttcttcaatg tgattttctt tatttcagtc
     2101 tctggaactg gtacgacgga gatctctgga ttatccatgg tcatgccact tttctttcaa
     2161 gtaatcgatc gtaagaaaag tcgtatcagg gacaagcggg atctcctctc caaggtcttc
     2221 agcacgtccc acgccaattg gttgagcgcc acttgagagg atggcttgga taccggcttg
     2281 cgcgtcttcg atcccgatac attcttctgc ttttagtccg acagcttttg ctgcaaggag
     2341 gaagatatct ggcgcaggtt ttccgtttgt tgcttctgcc gggtcggcaa tagcatcaaa
     2401 gtaaggtgta agacccattt tttcaagtag gaatggcccg tttttacttg cagaagcaag
     2461 agcaatcttg attttttctt cttttaaaga atccagtaaa ggcacgaccc cggggaagac
     2521 atcttttggt tcgatcgtct ggatcatctc taaataataa tcgttttttc ttttcgctaa
     2581 ttctgcaaat tcttcctttg aaaaagagtg ttcttttccg ccataagcta aaagcaaaga
     2641 gagtgagtct tctcggctga cgccttttag ctgttcgttg aatgtgtggt cgatcgtaat
     2701 gccgatttcc tgaccaagct ttcgccaagc acgataatgg aattcagcag tatcggtaat
     2761 gacaccgtct aaatcaaaca ataccccttt aaacatttgc ttcctccttt cttagcgtta
     2821 tttctagacg atccgctaaa gaataagact gttcatagac gtaaatttct agaggagaac
     2881 cttctaataa ctcgaaagta acttgttcat ctgtgactga gatgaacaat aaacgtccgc
     2941 gataattgat atggaaagaa taagctttcc aagtttttgg cagaaatggt gcgaatctca
     3001 actgatcatg ggcagttttc atttgagcaa atccttggac aatcgacaac cagctaccag
     3061 tcatggaagt gatgtgcaag ccgtcttctg tgtcgttatt gtaattatcc aaatccaagc
     3121 gagctgttcg ctggtacatt tctacagctt tgctttccat tcctaattct gctgctaaaa
     3181 tcgaatggat acttggcgaa agggaagact catggacagt cattggttca tagaaatcaa
     3241 agtttttttg cttttcttct tttgtaaaag tatcattgaa gaaataaatc ccctgtagta
     3301 catctgcctg cttgatgaag caagatctaa ggattttgtc ccaagaccaa tgctgattca
     3361 gaggaagatc gcttgtggga atatcggata caggcatgag atctttatct aagaatgtgt
     3421 catgctggac aaagattcct aattcttcgt caactgggaa gtacatgttc tctgcgatat
     3481 ctttccattt ggctagttct tcttcgctga tagtgatagc agcttctttt tgataagtta
     3541 aataattttc tcgcgtgtaa cgcaagaccc aagctgcgat cgtatttgta taccaattgt
     3601 tattgatatt gttctcatat tcgtttgggc cggtcacacc gtggatcatg tatttatttg
     3661 ctcgttttga aaaatggaca cggtctgccc agaagcgtgc gatttctgct aaaacttcca
     3721 gtccttcatt tttcaaatat tccgtatcgc cggtgtaatt cgtataattg tagattgcat
     3781 aggcaatcgc gccatttcgg tgaatctcct cgaatgtgat ttcccactcg ttatggcatt
     3841 cgacaccagt gaaggtgacc ataggataaa gcgcgccttt taatccttgt tgctgagcgt
     3901 tgtggattgc ttgcggcagt tgattatgcc gatatttcag cagattctta gttacttcag
     3961 gtttggctaa agcaagataa agagggacag catacgcttc tgtatcccag taagtggctc
     4021 cgccgtattt ttctcctgtg aatcctttgg ggccgatatt caatcgttca tcttcgccgt
     4081 agtaagtaga gaatagttgg aacaaattga atcgaatacc ttgttgtgct tcttcgtctc
     4141 cttcgatgac cacatcggca agcttccatc gttctgccca agccgctgtt tgctcttctt
     4201 ttgcttggat ataattgttt gtctggttcg ttaattctga gacagctttt tctgcttgct
     4261 gcgcttctgg aatatctcta ctagtaagaa cgataatttc tttttccact gaccatgtct
     4321 caccttgaga taattctgca gacaagcaac catgtaatgc taaagtatct tcgtgatagt
     4381 cagggatgac tgattttcca ttaacgaaat ggcgcattgc tgcagtaaca gtaaattgtt
     4441 caatcccaaa gttgtttgga atagttttag tcgtcaaata gccgatttct tctatagttc
     4501 cacgatcaat ctcattccaa aaatgttcat catagttgct gtcttcgttt tgaacatttc
     4561 catccaattt tgatacgagt ttgactgttc cgctaccttc aagcatttct atagttaaat
     4621 agatataagc tgattctttt ttgacaatgc tcagaaaacg ttcgaaggaa atgcgtactt
     4681 tattagtaga agtagtgatt gtgaatgtac gagataatac accatttttc atatctaatt
     4741 cccagtaaaa gtcttctggt tccaaagaag ccaagtcgat cagctgatcg ttgatcgaaa
     4801 tatctatcgc gataaagttc aaggcgttga tcacttttcc aaagtattct ggataaccat
     4861 ttttccacca gccgacacgt gtcttatcgg gataccagac acccgccaaa taagtacctt
     4921 gatggtggtc ccctgagtaa gtttcttcaa agttcccgcg catccccata taaccgtttc
     4981 caatacttgt taaagattct tgcagtcgaa gatttttttt atctaattgt gtcgtgctga
     5041 ttttccatgg atcaatagca aatagtcgtt tgatctgttt catttttctc ctcctaatga
     5101 gctgttttat acgttcataa taaacgcaac cgattgcaca agtcaataga caaaagaaaa
     5161 tatttcatag aaaaaagctt aaaaaaataa atttttagga gaaaattata gaagggaaca
     5221 cacgtattat aggttttata gaatggtata gacagaaaaa taaaaaataa agcatttaca
     5281 aaaaagaaaa cgcacgctat aatacgttta acgaaaccga ttgcgtaaag gagctaaacg
     5341 gaatgaaaaa gatatttagt tttgaatttt ggcaaaaatt tggaaaggct ttaatggttg
     5401 tggtagcagt tatgccggca gctgggttga tgatcagtat agggaaatca attcccttga
     5461 tcaatcctga ttggacgccg cttgtcacaa cgggcggagt aattgaaaat attggttggg
     5521 caattattgg taatcttcat attttatttg ctttagcaat aggaggaagt tgggcaaaag
     5581 aaagagcagg cggagcattt gcagctggga tctcatttat tttaatcaat cggatcactg
     5641 gggctatctt tggtgtcaca agtgacatgc ttgcgaatga agatgcattt acccacactc
     5701 tgttcggtac gaagatcatg gttaaaggat tttttacaag tgtattggaa gcaccagctt
     5761 tgaatatggg agtattcgta gggatcatcg ctggatttgt cggggcaatg gcttataata
     5821 aatactataa ttatagaaaa ttgccggatg ctttgtcatt tttcaatgga aagcgctttg
     5881 ttccgtttgt tgttatctta tggtcaacaa tcgtggcatt gattcttgct gtggtgtggc
     5941 caaacgtaca ggctggaatc aataattttg gtttatggat tgcagaatca caagaaagcg
     6001 caccgattct agcaccgttt ttatttggaa cattagaacg tttactattg ccatttggat
     6061 tgcatcatat gctgacgatt cctatcaact atacacagct tggcggatcg tatgagattt
     6121 tatcaggcgc acaggcgggg acacaagtat ttgggcaaga tccgttatgg ttggcttggg
     6181 ccactgattt agtgaatctt aaaggtgcag gggatatgtc gcaatatgag tttgtgttgc
     6241 ataactggac gccggctcgt ttcaaagtag gacaaatgat tggttcttca ggtatcttga
     6301 tgggaatggc ttttgcgatg tatcgtaatg tcgatcctga taagaaagca agatataaat
     6361 caatgtattt ttcagcagcg ttggctgtct ttctaacagg tgtaacagaa ccattggagt
     6421 tcatgtttat gtttgctgct gtgccattat atgtcattta ttcagtgatc caaggggctg
     6481 catttgcgat ggcagatatc ttgccattgc gggtccattc atttgggaat atcgaattgc
     6541 tgactcggac accgttagct atcaaagcgg gtctaggtgg agatcttatc aacttcgtgt
     6601 tgtgtgtgat cgcttttggt gttgttacgt atttcttagc aaatttcttg atcaaaaaat
     6661 tcaactttgc tacaccggga cgtaacggaa attacgacaa tgacagtgaa gaaaccgttg
     6721 tatctaacag cggaacagga acagcagatc agcaagtggt ccagatcatt catttgctgg
     6781 gaggaaaaga aaatatcaaa gatgtcgatg cttgtatgac tcggttacgc gtaagtgtaa
     6841 atgatcgaga aaaagtaggg actgaagaag cctggaaacg agcaggggcg atgggattga
     6901 tcgtcaaaga caatggagtc caagcagttt atggaccaaa agcagatgtc ttgaaatcag
     6961 atatcgaaga tctgctgcaa tcaggagcag agattccaga gccagaaatg gtttctacag
     7021 gaaatggaca agcaggtagt aagcaatact taggtataga acaagaacta gtttccgcag
     7081 cttctggaga agtgattcct ttatctgaag taaaagatcc ggtattctca caaaaaatga
     7141 tgggtgacgg ctttgctgtt attccaacat caagagaagt tgttgcgccg atcgctggaa
     7201 aagtgacaag tattttccct agcaaacatg caattgggct ggaaacgaaa gatggtatcg
     7261 aagttttgat ccatatggga atcgatacag tccaaatgaa tcagccagct tttgagattg
     7321 ctgtcaaaga aggccaagaa gtaggaacag gaacgaaatt agctgagatg gatcttgatg
     7381 tgatccaaaa cgaagaaaaa gatccaacga tcatgatcgt atttacaaac gataaagtag
     7441 aagaagtagt gatcaagcaa ttaggtacag tgacagctgg taaagtgatc ggctccatta
     7501 aaatgtaagg agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa cagccaaaca
     7561 aaaatagctc ctcctatttt tcgtttggtt gggcttatta ccgagaagca gcagtttgaa
     7621 tactgtttag tggagaggtc gtgaaaaagc tgccctgcac caagtgataa aaacagccaa
     7681 acaaaaaata gctcctggtc cattgagctt attactgagg agttagcagg agaacactat
     7741 ttgctggaga ggttgtgaca aaaattttgt cacaaccctt ttgtttcgaa atgaagacaa
     7801 ggagaaaacc aatgaaattc atgacactca acacgcatag ctggcttgag ccagaaccag
     7861 agaaaaaatt gcaagaatta gcagataaga tcctgttaga agattatgaa gtgattgctt
     7921 tacaagaaat caaccaatta ctggaatctg aagaagtaga acctgcgaag ctaatgaagt
     7981 tctgtccggt aaagaatcaa gtacctatcc gtaaagataa ttttgcctac cgtttagttc
     8041 agcttttaaa ggaacacgga aaagagtatt tttggagttg ggaaatgagc cacatcggtt
     8101 atgataaata tgaagaagga aatgcactgc ttacgaaaaa aacattggaa agtcaggtcc
     8161 ttaccgtctc ccaatttcaa aagaaagaag attatcagac acgcaagatc ttgattggga
     8221 aaacaaagat agatgatcag gacatttttg tctcgagctg ccacttttct tggtggacag
     8281 ataaaaaaag tggcttttat tttgagtgga aaaacttgga aaactacttt ttggaaactc
     8341 gcgtaccact ttttttccta ggtgatttca ataatccagt agactctcaa ggttattata
     8401 ctgtaagaga aagttgcctt cttcttcaag attcgtatgt tgtcgcgaat gaaaaaggaa
     8461 aagcagctac tgtggaaaag aaaatagatg gttgggaaca aaatacagaa aaattgcgta
     8521 tagattttat tttcgtccct gaaggaatgc aggttaaaaa atatcaacgg atttttgatg
     8581 ggatcgatag tccaatcatc agtgatcact acggggtgga aatcgaatta gatgtgaacg
     8641 aataaaaaat ataacatata acataaaaaa actgattaaa ataaaactct ccaaacgatt
     8701 ataccgtttg gagagttttt tgatcggatg tatttatccc ttttgcctaa gcacgtaaaa
     8761 gcttgtatct atgataaata aataaacata gcaaggtaaa ccagccaatc aaagtaagag
     8821 aaagaatgaa atagaaatag attggcgttt gataatgaag cgtgagctcg ttgattcctt
     8881 tttgctgctt cacgattggg gtcccgatat ctgttacttc ataatcagtc aatgtttttc
     8941 cattttgctg tagcacagtc cgatcgtaga cgataacagg gatatgaaca gttttgtccc
     9001 cagtgttttt ccacttgatt gtcaaaagac cgcctggatg tgtttttata aaagttgttt
     9061 cgttttctag tatttcttcg ttataccggt cgtatttatt gtcttttgtc tccttataga
     9121 ttggcagata gtcaggtgtg gttttttgga aaacgaacaa gctggtagac atatctttgc
     9181 tgaagaatgt tttccttgct tcttccggcg tatcgaatag ataagtatgt cgactgacaa
     9241 atgtttcatt ttcccacttt tccagatgct ggtataagtt ctggatcgtc tgtgctgaaa
     9301 aaataagaat gccaaatata cttaaaagac ggaaccactt ttgttcagac cactggttca
     9361 gtgaaagggc aaggtaaagt agaagcaata gcgtaaatgg cacgaaaaat cgaaatggaa
     9421 actggatcaa actaataaaa ggcacatttt tttcgatcaa tgtcgtccat ggaatcaagc
     9481 tagtagaaag aaaaaagaaa acaagacttg tgtacaacac gattttttgg aataaggtgt
     9541 tcttttgttg aaagaaaata aaaagcaaaa aacctgataa tatcaatata ggaaaggcct
     9601 tagggtaatg gagccaataa ctgccatcca gatctatcgc cttttgactc atttctctgt
     9661 taacaaaggg aggaagaatc ttattcccac tgtaaacaat agctaatcct gcccaaatat
     9721 ttgctgtcag aacaaaataa agcaagaccg acttaatcag ttgaagcagt gcttttcctt
     9781 tttcagtctg gttaaaaaag taataaagat aaaaagggat atacatcaaa gctaacatga
     9841 tcgaagacag taaatggatc tgtgtcataa gtcccactga gacagcgact ttgataacag
     9901 ggaacttttt atgaaggacg aaatcagcaa tagggatcat acataaagga taaaaacaag
     9961 tcccccagct agtgaatcct tggttgatag accagtattg aatagaatac gtactcatga
    10021 ataaaacggc tactggtaca cttacccaat ttcgaacatt gacatatctc agtaaaatca
    10081 gcatagaaaa tcctgaaata agataaagaa tgaaatttga aagaatctga taatgaaacc
    10141 agctacctgc aagcaacacg atcaatcctt gtaaataagc gaaaaatggg ccgtaaacgg
    10201 cattcacgat cctgccactt tgctggaatc cataaaggga aggaaaataa tggaaatccc
    10261 catatttaat ttgttgcgcg gcatcataga accgattgta atggaatggg gcatcagcac
    10321 ccaaaattag tttatgtgtg aataaatgag gcatgagaaa tgccaaagca atgaaaaaaa
    10381 ttgctaaaaa tgggccatat tttttcaatt gtcgaactcc tttgcaaact ttagataaat
    10441 tcatcatata tcctatgcga gaggtaggca agaaattaga aaattcatga aaatatttat
    10501 gaattttaca agaaaaacat aagtgaaagt tctaaggaga gaggatgcga cataagtttt
    10561 gttgcatctc cttgttttga aacagaattt ttcttaatac tcgaaacaaa gtagcttttt
    10621 catgacctct cggtaaacgg tgttcaatca gctgcttctc ggtaataagc tcactagcct
    10681 agaaaatatg agaagctatt ttctgactag cgctcttatt actcaaagca taacgcagtt
    10741 ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    10801 caacaaaaaa tatgagtagc tatttttttg ggctgtactt attacttgat gcaggacagc
    10861 tttttcacaa cctcatcggc tttcattttc tatttttttc ctgaacccat ataataaaag
    10921 aaagaacaaa aaaacttgca agggaggaca catgtgaagc agagtaagca aaaacagtct
    10981 cgtcgacttt tgtttcgttt gtttttatta atatgtatcg tcgtagggtt actgatcgct
    11041 ttatatccat tttatgtgga ttctttaaat agttttattg atcaaaaacg tatcgaacaa
    11101 gtacaaaaac ggaccgcagc tgaaattgaa gtgcagcgaa agaaaatgga ggagaaaaac
    11161 caacgattaa ctgaccaagg attcaatcct ggtactgatc ctttcaatga aaagaacaga
    11221 aatgaaagta caacatccag tcaattagag gaatggctga tcggaagtat caatatacct
    11281 aagatccaat taaatatttc actttatgat cggctcaatg gtaggatcct tgaaaatgga
    11341 gcaggcgtct tgcaaggaac ctctttcccg cttggtggaa attcgacgca ttcagtgatc
    11401 tctgctcaca gcggtttacc taatcgacgg ttatttaccg aattagatcg tttagaaaac
    11461 ggagacacgt ttattttgac tgttttgggg gagaaattgg cttatcaagt taaaaatata
    11521 caagtggtac tgccagatga cacgtctgtt ctaacgattt cagaaggaga agacttagtt
    11581 accttgctta catgtacgcc gtatatgatc aacacgcatc gtttgctagt gacaggacat
    11641 cggattcctt ataacgaatc ggtaaaaaaa gaagaaggaa aaggaaatca ggaaagaacc
    11701 atgcggcaat ggtttattct tgcaggaacg ataatagctg tagtcatact gttagtgttt
    11761 atcggacgac taatctatca gtatagatta agtaaaaaag tgcttgattt ttcatttatt
    11821 attagtgatt cgtcagggaa accggtaaat ggtagttcat tcattttgaa acataagaaa
    11881 aaaacactta ctagaaatgg tgtgccgttt tcagtacaaa gcgaccatca tgggaaagtc
    11941 aagctggatc aattgcctgg tggaacttat cgaatcgttt cagctgatga tcctaaagtt
    12001 gctgtttctt ttggtattag aaaagtaaaa caagagaaga tatacttttt tgaggggcga
    12061 aaacttgtaa aagagcttca aaaaaatggt ttttatttta aaatcaatga ataagtaagg
    12121 agagaaaaaa tgatccgcac aacaacaaaa ttgtctgcca aagaactgga atctgttcta
    12181 tcgatttggc tgcatgctaa cttggattct catgaattca ttccatcaac ttattgggag
    12241 aatcaagtag aatctgttag gaaagcttta ccagatgcag tgatttactt agcagaaata
    12301 gatcaagaaa ttattggttt tgctggggtg attgatcagt ttatcgcagg aatctttgtg
    12361 aaaagggaat accggcaaca aagaatcggt acgcaactaa tgaaaaaaat aaaagaaacc
    12421 aataaaacac tgactttgac agtctatcaa aaaaatcaat cagctattca tttctatctt
    12481 tcacaaggtt ttacaattca aacacagcaa aaagatgaag cagtaaatga ggaggaactt
    12541 gtgatgaaat ggaatcaaaa cgctgatttt tgatgaacag aataacgaaa taatgctccc
    12601 agcctaattt tttgctggga gcattatttc attttgaagt cactaattta actgtgtgaa
    12661 tatgcagttg ttacaatctt tgataaacgg tgttcaatca gctgaccctc ggtattagct
    12721 caaaaaacgg caaaatatga ggaactattt ttccatttgt ttctctaata ctcaggtcaa
    12781 aacgctgatt tcacaacctc ttgataaacg gtgttcaaac ggctgcttct cggtaataag
    12841 cccactagcc tagaaaatat gaaaagctat tttctaacta gcgttcttat tactcaaagc
    12901 ataacgctga tttcacaacc tcttgataaa cggtgttcaa tcagctgacc ctcggtatta
    12961 gctcaaaaaa cggcaaaaca tgaggaacta tttttccgtt tctttctcta atactcaggt
    13021 cagaacgctg atttcacaac ctctctttca caaccttatt ttactcgttt ataattttca
    13081 tcgaagtatt ttccgctacg gatatcatct ggcattccat cgtatggttc ttcgctaata
    13141 acatcttcat tgtctatacc tgcatcaccc atataagtga tcgtagcaaa ttcaggaaca
    13201 agtaattttg gataagtttc atatttttca cgagctgctt ccatttctgc gatatgttcg
    13261 ttttggaaag taacagtgat ttctggatgt tcttcaaccc atttagggaa aaagatcatt
    13321 ccgtgaagtt tcttttcatt tggcataaag tccaatgcca cgtctgtccc tgttggctct
    13381 gtccaagtga ttttgaatac gccgtccgtc aatttaacga tatcagcttc ttggtctttt
    13441 acccaacggc ctttgaccat tccgccatgg atacggtaat caacagtatg gtcatttttg
    13501 gcataccatt catattccca accattgtca tacgtataga taaagtgagt tccaataaaa
    13561 tcttccaatt ctttaaattc tttcatgttt aagcatctcc ttataaatta aaacatgtaa
    13621 taaactacat gttttcgatt actcatttat gatagaatgg atttaaagat ttgtcaagga
    13681 gggaaaactg atggcaagaa aaaatacact tcgatatatt ttgttagggt tattaagtaa
    13741 gaagaagatg acaggatatg aattgaatca atcgttcaaa aatgaaatag gagaattttg
    13801 gcaagcaaaa catagtcaga tttatcctga acttgcaaaa atggaagagc aaggaatcat
    13861 tcagcatcaa gtagagatca caggtgaaaa attggaaaag aaagtttatg aattaacaga
    13921 agaagggaag gaacaattgg cagagtggat tcatacaccc accaatgaac taccggttaa
    13981 tcgagacgaa tttgttctga aattgtattt cgtcaaagac gtgaatgatc cggcattagt
    14041 agaaattatt cagcagcagc gtgaccttca tgaagaaaaa cgacttcatc tattagagcg
    14101 aaaaaaaacg atctttccta ctgaaaaaga aaaacatgaa aattacggac actacctgat
    14161 tttagcgcat gcgatcaatc gggaaacaga atatgcaaat tggctaacag atgtattaga
    14221 agaaagtaac cgaaaaaaat aaaaaaatat ccgaacagtg atggagaatt cctttctata
    14281 tgaaagaaac gcagatcacc gttcggatat tcttatgttc aaacaggcct tttttcaagt
    14341 atttatgtag catctactta ttaaaaagct tggtacttag gagattagtg gcgtttagag
    14401 ttcttttaac aactgttcgt agtcagcttt ttcatcgaca ggaaggagct tgtaagttaa
    14461 ttcgtctgtc tcgttgtcat gaatgatgta catcttagca ttctcttctt tgaagttacc
    14521 gatttgtaaa atcgtatagc gttcgtcgat caattcgata tctttgattg cttttgaaaa
    14581 aactttacgg acatggtgca ttttcttttg gcggatttct gccttttctg cagcttttga
    14641 caaagtaaat ccgtcatcta aatatttttt gatcagttct acttttatga ctgtaggtaa
    14701 acgatatttt ctaggacaat tcgcatcagc ttcgatcgaa cgaatgaatc ccttttgttc
    14761 ccaatacctt aattgacgtg gagacacacc tacgatatca cttaattcac tgatgccaac
    14821 aaccaattga tcattttcca acaaacgttt aagggaagcc ccaaccattt ttgtcactcc
    14881 ttttgtcctc ttgcttccct taattatatc cgtattaact tatgtgtcaa gtaggttgac
    14941 aaatagcgaa tttaggacta aagtattcta gtagtttcag aaaaaattca gaaagaagga
    15001 gaaatatgag taacaaccaa cccgtagata tttacggaaa accatataat cggacacttt
    15061 tagttgttgt cttattaatt ggtacatttt gtaccgtttt gaatcagacc ttattgacga
    15121 cagcttttcc tacattgatg aaagctttcg atatttcagc gtctgatgtg caatggttaa
    15181 cgactggttt cttgctagtc aacgggatca tgatcccaat aacagcatgg ctgatcaata
    15241 aattcagttc aagaaattta tatctttctg ccatgacgat ctttttgatc ggaacgatta
    15301 cttgctttac agcacctaat tttagtacat tactaatcgg tcgtttgatc caagcttgcg
    15361 gtgtgggagt atcgatgcca ttattgcaaa atatcatgct atctattttc ccgccagaaa
    15421 aaagaggatc agcaatgggg atgtcaggga tcgttattgg acttgctcct gctttaggcc
    15481 ctacattatc tggttatatc attgataact accattggcg tgacttgttt ggtatggtac
    15541 tgccaatcgt tgttcttgtc ttggttttag cattcttcct aatgaaaagt gttattccat
    15601 tgtcaaatcc tagcattgat attttatccg ctattttatc aacgattgga ttcggtagtt
    15661 tactttacgg attttctagt gtaggagatg acggctgggg aagcttgaaa gtaattggtt
    15721 tcttagttgt tggtgtgatt ttcatcgcct tgttctcatg gcgtcaatta catttggaac
    15781 atccattctt ggaacttcgt gtattcaaat catctacatt cacgattgca gctgttttag
    15841 ctggtgtaac aaatatggcg atggtagggg cagaaatggt cgtaccattg tatattcaaa
    15901 atattcgtgg agaatcagca ttccattctg gcttgatgtt gttgccgggt gcattgatca
    15961 tgggggctat gatgcctgtg acgggtgcga ttttcgataa atacggcgcg aaacgtttag
    16021 ccatcacagg gatgttcatt ttgacagcgg caactgcacc atttgctttc ttgacaaaaa
    16081 cgactccagt tttatatatc gtgatccttt atgcgatccg tatgtttggg atctccatgg
    16141 tcatgatgcc ggtaacgact tctggtatga atgcattgcc aaataacttg atcagtcatg
    16201 ggacagcggt aaataataca ttccgtcaaa tcgcaagctc gattggtaca gctattttga
    16261 tcagtgtgtt gacgaatgtg acaaaagcaa atatcccaag caaatctgta ttggataata
    16321 cgccattagc ttataaagat caggcaatca atgccacact gtcaggttac catgccgcgt
    16381 ttatcgtagc gatcatcttt gggattcttg gctttattat tgccttttta ttgaagaaaa
    16441 aagaacctgt tctaatgaaa gcgggggata atgcatgatt attggagttt tgattgtcag
    16501 cttgcttgct tttgctttaa cgaacgtgtt cgctaaaaaa acatggcaaa cctttttatc
    16561 tttgattttc ggactaatct tcgtcgcttc actaagtttg atcgtcgcta atttgtccaa
    16621 tcactttgga atggaaaaag taacggaaac aaaaacagaa aaaattgttt ccagtgctga
    16681 ttcccaagga gcagatatgc ttttgtataa agctttaggg aatggaaaag aaaaagtgta
    16741 tctttaccga acaaatgaaa aacaagaaaa accaaaagca actggtacgg ataacgaaac
    16801 aaataaagta gaaaagacag acggcgatgc tgaaaaagtg acgaaaacta cttattggga
    16861 atacaaaaac gacatgtata aattctggtt caatattgct gataacaatc acgaatatga
    16921 cagccgagtg aatacattca aaatcccaga gacatgggta gaattaagta cggaccaagc
    16981 agccaagtta gctgaattag tgaagaaaca gcaaagtacg atggaaagtg aagcaaaagc
    17041 ttatgttcaa gacggtatgg taaaagcaat gactgaaaat ccaaaaatga gcaaagcaga
    17101 gcaagaacaa cgtacgaaag ccttagctgc tgaattccaa caacaagcat tcgcaaaatt
    17161 agtgaaagaa gcaaaaggcg aataatattt tgaacaccat gtaggaggtt gtgaaaaagc
    17221 tgctctgcat caagcagtaa gaacaatcag ataaaaatag cactccatat ttttcatctg
    17281 attgggctta gtgccgtaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgagc
    17341 ctgccgttta actctgagtc acaaggagca atttcaaaaa acagcttctc atgtttgttg
    17401 actattgtga cttgtgaccg aggagttggc aggagaacac cgtttattcg aaaaaaggaa
    17461 ctgcgacaag acttttgtca cagttccttc ttttttttgc tatgctatac tagatgtaaa
    17521 aaataggaga aataaaatga gggaaattta ttcttttgaa tcaaaaatct atgcttccga
    17581 agtcggcaag ggcggggcat atattatttt tccgtatgat ataagaaaag aattcggtgc
    17641 tggaagagtt aaagtccaag caacttttga caatgtgccg tatgaaggca gtatcgtgaa
    17701 tatgggcgtg aaaaatccag atggttcagt ctgctacatc cttggactac gaaaagatat
    17761 tcgtaaaaac atcggaaaag aaatcggtga tattgtagca gttacagtga agcaaaaata
    17821 aaagaggttg tgacaaaaga cgtgtcacaa cctcttgata aacggtgttc aaaagccagt
    17881 ttctcggtag taagtcaaat ttatgcaaaa atgtggaaac ccatgtttac aaaatttttc
    17941 ttactactcg aaacgaagcg gctttatcac aacctcttga taaacggcgt tcaatcagct
    18001 gtccctcggt attagctcaa aaacggcaaa atatgagaag ctatttttcc atttttttct
    18061 ctcatactca ggtcataacg ctgatttcac aacctcttct ttcataatgg tttttcacca
    18121 tctttataat aaactggttc tttgatatgg aaatctattt tttccaacca atctaaaatc
    18181 ttgtaaccta actcttctga catcggaaaa gaggcgttga tttgtgcatt ggagatatgg
    18241 tcaacatgga taccggaagt gatcgtacaa cttcccggaa cggcagtttt gatgatcaca
    18301 gctatttttt cggctaagac atcgtcttta tggaaccgac catcgtggct agggaaacgt
    18361 acagtttgca tctctgtatc acgagaaaat gtagtgactg ttccgatatg tggtgtatct
    18421 ccgcctgtta aagtgatcaa taagtcttta ccgattactt taacagcagc ttggatcgtg
    18481 aaacctagtt tggttacttc aactatcgtt tctttttcca tattaatcac cctgccaacg
    18541 ttttgaatgc tcatttacaa tttcaaattg atccaaaagt ttcattgtat ggtgattaac
    18601 aagatcttgg atcgtttgag gctgattata aaaagcagga attggtggta tgatttgcac
    18661 acctagtcgt gctaatttag tcaagttttc caagtgaatg gcatttaatg gcgtttcacg
    18721 aggaacaatg actaactttc gttgctcctt cattgttaca tcagcagcac gtgcaatcag
    18781 gttgtcgcct aaaccaacag agatacctgc gactgttttc atacttgccg gtacgatgat
    18841 cattccatcg gtcaaaaatg atccgctggc gacagcagca cctaaatctt tgtttgaata
    18901 atggtaatca aacaggcttt cgaattcagt tagtgataag tcggattcca gctttaagtt
    18961 ctgttttgcc catggactga tgattccgtg tgtttctatc atcggatatt cttttagttt
    19021 cttcactagg ttgatggcat aaatggtgcc tgaagcgcca cttacaccaa tcacgatttt
    19081 tttcttccgt tgtgccaatt gttccatttt ccgcactcct ttttatgatg tcaaaacagt
    19141 tgcagatcat tcattatttc aaatattttt cccaatcttc tacttcttgg aattttgcac
    19201 gtacaaaatg ttctttcata tcgaaaggaa ctgtaccgtc aaagatagtt tttgcactta
    19261 tcccacggaa acgaatagag ccaggattat attctggtaa ttctgatggg tccaatggat
    19321 ggttcctcat tcctgggatc acgatgatat ctttatctcc ttggaaacga gtgttgaaag
    19381 tccaaactac atcgttcatg tcgaaaatat caacatcttc atcgactaaa atgactgtct
    19441 tcaattcttt gaaggctgat aaagcaagaa tagctgcttg acgctgaata ccttcatccg
    19501 cttcgttttc tttacggatt tgcatgatgg tcatcaattt accaccacct gcaggaggat
    19561 tgtagacatt tactactttt cctggaatag ctttatcgac caaggcaaga atacttgctt
    19621 ctgtaggaat accggccata gatacgtgtt cttcactggg accaatcgtt gtttgcatga
    19681 ttggattgtc ttttcggtga gtaactgctt tgactttcac tacttgtaca gctggattag
    19741 catccccagt atagccagga aattctggca ttgcttttcc tgagttcgtg ttgatatctt
    19801 cttgcattgt ttcatttggc atgatttctg cttcaatgat gaattcagca cgagcaatac
    19861 ccacttcatc gactgctata ccatcaacga tttgaatagg ttcgttacgc aaagctcctg
    19921 cacaccatag ttcattgtag ccaagtggag tggtaggtgg ttcgaaagtc gtgccaatgg
    19981 caattgctgg atctaaacca atattgatag tgataggcat tggtttattc aaggcttcga
    20041 attgtttttg gaagtgacca atgtggcgtc cgccaggcat gatgtacata ccgatcgtat
    20101 ctttatcttc tagaaccata cgatggatcg ttacatcgct cattgttttt tctggatctg
    20161 atcctaagac tacacccatt gtgatgtatg gaccagcatc ttcaggagta tttgtaggtg
    20221 caggcaaaat gttgcgaata tcgaagtctg catcggtagc tagatgaacg acttcttgtg
    20281 ctggagcgtc tgctttgtct actttcacag gtttgattgg attttctaca gcgtctttca
    20341 agaaacgacc aagtgttcga taatcatggt gcaaaatttc acctacacgt ttacgactag
    20401 ccattgttcc gatgttcaca cgtgtgccgg ggaaaccttt gatattgttg aaagtcatag
    20461 ctggtccttc ttgagtcgga cgttttactg taccgccagc accgatataa cggtaaacac
    20521 cagataattc tgcttcagga tcgatttcaa tatctgtttc gtgatattga cctggaagtg
    20581 tttttagttc ttcgatgact tttcttaaat catacggttg atctgtcatg agagattcct
    20641 ccttagttgt ctttacctat ctatagtaaa aggtgaaaaa gaggaaaaca attcaacttg
    20701 ttcggtaaag tattctacaa tggaatggat gcgttttttt gataatagaa taaactatga
    20761 tatacttatc actaaaagaa agcgcatact tagtgttgga ggaaggaaag tgaaaaaaat
    20821 ggaggagtca tttcctaaag cagtaaaagt ggaaaatata gcgaatattt tgaaagttac
    20881 atttgaaaac ggagaagtaa aatacgtgaa atctcattgg acagaagaga taaccgatgc
    20941 cttgcaattt ggaaaaaaag gaagaggaaa aagaaaaaat cttctcgcac tttctcgtaa
    21001 tatgtggatt gggactgaag taacgattga agcagatgga acagtattca taaatggaaa
    21061 agacaggtat acgccagaag agttgtggta caaaggaaag aaaagtatac cagaattata
    21121 aaaaataatt aaaaaaaaca gcgcgaaaca aggaacatat tacttcctcg tttcttgctg
    21181 ttttctacta tttcagcgct cttatgactc aaatctaaat gtggttgtca caaccttatt
    21241 ctgcacgcaa agcgatagcg gcgtcttttt tcgctgccat tcgtgcagga agatgaccgc
    21301 caagcatcgt caatatagta gagacgatca ctagaataat cgcatggaca ggatttagtt
    21361 gagcaacatt ttttagatcc gtcatgttgt ataagatgct attgataggg aacgtagcta
    21421 gccatgcaat aaacacacct aatatcccag aagaaatacc taaaatacac gtttctgcgt
    21481 caaatacgcg agtgatgtct tttttacgtg cacctaaagc ttttagtaca ccgatttctt
    21541 ttgtccgttc aatcacagat gtataagtaa tgatactgat catgatcata cttgttacta
    21601 aagagatccc tgcaaaagca ataaggacat aagtgatagc atccatcaat ccgccagtca
    21661 gttcagtcat cgttccagct aaatcagtat aaatgatttt atcttcatct gatttgcctt
    21721 tattgtaatc atctagataa tccaagatct tttctttgtc ttcaaaattg ttcggataaa
    21781 tcatgatact tgaaggcaag ctgtctccac ctaaataact aagcaatgtt tgtttggcat
    21841 tttcgtcaac tttttcagta gttaagacat ttacaccact gtctctttga gctttgacga
    21901 tttctgattc tttgttttcg ttgacgattt gagtcgttaa ttgatcgcta taagcgattc
    21961 ctggagataa gagattcatt gtagaagaag atttcacgcg taggatcccc gagatcttca
    22021 attcatcaga agcattctga tacatcgcat cataatctgt attagggata aaattcccag
    22081 ttggaagttt tgtatagtaa gtattgttgt ttactaattt gaatgttgta ccaacgatat
    22141 catcaaaatc aagtttttcg tcttctttca catcaaatcc aagattcttc aatgcgttga
    22201 tattagtatt attattgccg tctacgatca gcacgacatc tgttgctgag gctggataac
    22261 ttccggcaag taaagaataa ttgtctttta aaaagttttc tttgctagtg tcaagctgtg
    22321 tagggaaact tgacactccc acacctgtca tcgctgacat cgtactagat aaagaaagag
    22381 attccgtatc aggattttga ttcgagaagc tgacaggctg tactttgcca tttacatcac
    22441 gtaaaagatt gattcctgta gtacgggtaa atccgatatt attacttaag ttaggatcga
    22501 tgtctgttac gtaatcgacg tatgtttgat caatcttatt cgtgtgctgt gctttatctt
    22561 cttcgctgac ttttgcagta atcgttttgc tgtctggata atccgctttg cttgcaccca
    22621 atccggcatc gtcacgagtc tggttagtcg ttaccttaga aatagtaatc ggaaatttcg
    22681 ccatcgtttc agcttgcgtg ttatcgattt gtttttggaa tccagaagaa agggacagaa
    22741 cgatcgcgat tccgatgatc ccaatactgg aagcaaagga ggtcaagaaa gtacgtcctt
    22801 tttttgttcg gatattgttg aaggaaagct ttaacgctgt ccaaaaactc atctttgttc
    22861 tgcgtaagtt aaattgatca tcttttggtc gttcgatgtg aggatgggaa tctgttaaga
    22921 tcttaccatc agaaaattca atgattcgat ctgcgtattg atgggccagt tcaggattat
    22981 gtgtgaccat gatcactaat ttttctttcg ataactcttg gatcaattcc atgatctgga
    23041 tacttgtttc tgtatctaac gctccggttg gttcatcgca caaaaggata tctgggtcat
    23101 tggctagtgc tcgagcgatg gccactcgct gcatttgtcc accagataac tgatttggct
    23161 ttttatgcat atgatttgtc aagccgactc ggtgcaatgc atcttctgcc cgttttcgtt
    23221 tttcgtcttt agaaacacca cttaatgtca tcccaagttc aacgttttca ataatgccta
    23281 gatgaccaat caagttgtaa ctttgaaaaa tgaaaccgat agagttgttt cggtaggcat
    23341 cccagtcact gtccttaaag tctttagtag actttccgtt gattaccata tcaccggaat
    23401 cataattatc tagtccacca atcacattca gcatagtcgt tttaccagaa ccactaggac
    23461 ctaaaatcgc tacgaattct ttttgtctga aagcgacaga cacaccatcc aatgctttgg
    23521 tggtggtttc gccgacttta taatattttt ttatatcttt taattgaagc ataatcaccc
    23581 ttctcccgta ttgaaatatt cggtatacta ataagtatat cagaacaatg atcgtagtat
    23641 acgaaataaa tgttaactga agatgaacta caagaaaaaa tctagaaatt tttcaaaaaa
    23701 cagagggaga tcaatgaatc gtattttagt agtagaagat gatccgcaat tacagttgct
    23761 ttaccgttct gtgttggaac gagcgggctt ttcagtcatc accgcattga atggagagga
    23821 tgcgctgaaa aaactagaag cgacacgtat agaattaatc attacagata tcatgatgcc
    23881 gaaaatggat ggctatgact tgctagactc attacgtagc accagatttg acacacctgt
    23941 tctaatgatt acggcaaagg ccgattttga ggataagaaa cgcgggttca aattaggagc
    24001 agatgattat atgacaaaac ccatcgatgt caatgagatg atcctacgtg tggaagcatt
    24061 gcttcgacgt tcaaagatca attacagcag tagcttgata atcggacaaa caaaattaga
    24121 gctagatgct tatacagtgt tacaagatca gcattcgttg attctgcctc aaaaagaatt
    24181 tctgcttctg tataaattac tgtcttatcc caacaagatc ttcactcgcc aacagttgat
    24241 ggatgatatt tggggattag atacgaatac agaagaacga acgatcgatg tacatatcaa
    24301 acgtttaagg acccgttttg aaaagacgga agattttcaa atcatcacag tacggggact
    24361 aggctataag gcggttattt aaagatgaaa aaaaagctat tttcacaatt atggatctat
    24421 tttgctagta ttgtcttcat ttcgatctta gtgacactgc tgtgttttct cggttttatt
    24481 ttcttattgt ctcgacattc tatctcgcct gctgaatcgg ctggaaaacc aacgttatac
    24541 ccgttattcg tctttgcggg gttcagtatg gtcgtgggta caggaatatc gatttttgtt
    24601 gggcggcgta tcctgcatcc aatcagtgcg ctagggacaa atatgagtct ggtagcaacg
    24661 ggagattttt cgattcgaat ggatgaacag cagaaagtag cagaagtaca gcaactgtat
    24721 aaagatttca acgttatggt ccaagaactc aatagtatcg agacactgag gaatgacttt
    24781 gtgtccagtg tatcccatga attcaaaaca ccactagcaa caatccaagg atatgttcaa
    24841 ttgttacaag ccccaaatct ctctgacgaa gaacgccaaa tatttttata tcggattatc
    24901 gaaagtatca cgcagctttc acaattaaca gagaacatct taaaattgaa caaactggaa
    24961 aaccagcgta tccaactgga aaagaaagag tatcgattag atgaacaaat cagagaagta
    25021 atcgtttttt ttcagcctaa atgggagaaa gaacagctag aattggatat cgaacttgct
    25081 gcagtaaatt acacaggcaa tgaagagttt ttgtaccaag tgtggctgaa tatcatggat
    25141 aacgccataa agtacaatca aatcaatgga cagattcata tcaaactatt tgagacagcc
    25201 acagagattg tactggaagt gaccgattca ggtgtaggaa tgaagagacc agagatcgaa
    25261 tgtttgaaaa attttatcaa ggagatacaa gtcgtcaaat ttctgggaat gggctaggac
    25321 tttcactggt taaaaaaatt ctagaactgc atgatggacg tattgattat agcagtatcg
    25381 aaggagtagg aacgacagca atgatacggt taagtaaaca ataggaaaaa gaataaaacc
    25441 cctaaaaatt ctattgaagg tttttagggg tttttagtcg tttttttgtg attagggaaa
    25501 tgttcttacg gttcttttgg cataaaaatc gctgctttct tattgaacta cgagaaatgt
    25561 tagaggtgtc attgaaacaa ggacatgatg caagaaagag agcgaaagtc atgcgtcgct
    25621 ctcttttttt gggtggatag atggacagaa aatgtagggc ttagttttct tcttgattta
    25681 aatactccca aaatgtatct gaagccaaag aatgctcacc gactttacga gtaaatgcaa
    25741 gataactctc tgttgttgga gaaataggga gaatcacagt attttctttt aatagattct
    25801 tgactgtttt ttccataaca atagcaatcc ccatgtcatt tgcaatcata ttgatgatca
    25861 agtcgattct tgctccttta taagagattt ttggttcaaa tccagcttcg cgacacagat
    25921 ctagtacagg ttgatacaag ttcgtagtgg ggccaaggag caaaaagttc tcctttttca
    25981 gttcgcttag atccaatttc tttttactag ctaaaggatg atttttaggt agaactgcta
    26041 caaaatcgtc tgtttcagta ggcaaccact caatcgaact tggtggggcc tggaaacttc
    26101 tagcaaagtg gatcgtgtca ctatgttcat tggcgtcatt gtaagttaat tcgacacttt
    26161 ccacttcttt caactggact gtaaattcag gatggcgttt caaaaactcg gtgattttgg
    26221 aaaaaccttt ataattgatc attgtcggta tcgttaagat atttaatgaa agattgttgt
    26281 ctttcgtata ggtttcaagc acttcttgca tagcatggta ttgttctacg acatttttta
    26341 catatgggag caataagctt ccagcttcgg tcaattcgat ttttctatgg gcgcgttcga
    26401 ataatttgac gtctaattct gtttctaacg aaagaatctg tttagaaata tttccttggg
    26461 tggtgaattg tcgatcagca gttttggtga aattcattgt ttcggctaaa tcaagaaaaa
    26521 cttcgaattt atggatatcc atcatattcc tcctacttat tccaataaag aatactttaa
    26581 cacaaaaaat gaattggtgt aatcttctct gtctgttaca atctttcttg cagcgaaagc
    26641 aataattaca gaaatttttc tgattttttt cgcttcgtag aaaaagagag gagttttttg
    26701 atgccaactg gagttttgat caatgtaggt tccgttttgt ttggcggact aattggcgga
    26761 ttagtaggaa ataaattaag tgaacatttt aaagcacagc tgacgatggt ttttggtgtg
    26821 tgttcgatgg ggatgggaat ctattccatt gcgccgatga aaaatatgcc ggctgttatt
    26881 tttgctttag tgataggaac agcgattggt ttgattgttc atttaggtaa tgggataaat
    26941 aagggggctg cgctgatgca agtacctatt tctaaaatct tccctagtga aaagcttggt
    27001 atgacccacg atgaatttat cagcacatta gtgacggtca ttgttctatt ttgtgcaagt
    27061 ggtacgggga tctatggaag tttagattct gggatgacag gagacagtac gattttgatt
    27121 tctaaatctg tccttgattt tttcacagca gctatttttg cgtgtaattt agggtatgtc
    27181 gtttctgtga tagcaattcc ccaattcatt attttttata ttttgttctt attggcaaaa
    27241 tttatttatc cattgactac accagacatg atcttagatt ttaaagcttg cggcggattc
    27301 ttgatggtcg ctaccggttt tagaatgatc aacgtgaaaa tgttcccagt agctgacatg
    27361 atacctgcaa tgatcgttat catgccactg agctggatgt ggacaaattg gattatgcca
    27421 ctgttataat aaaaatcaaa gagaagccat tttttgctga ctaaaaagga tcaaatcttt
    27481 tagtcagttt ttttgtattt gacaaactga ttttgaaact atattatatg ttgtataata
    27541 tagattgaaa taaaatatta cacttgagaa tagaaggtga cgtaatgcac atccagattc
    27601 caactgttct tcttgatggt actgtgttag cagcattaag caaggaagat atgtatgggt
    27661 atgccttaac aaaaatcgta caagaaagtc tctctgtcag tgaatctaca ctatatccgg
    27721 ttttgagaag gttgaaaaaa gaaggatatc ttgagaccta tgatgaacct tttgaaggca
    27781 gaaaccgtcg atattactcg ttgacaccaa tgggaagtcg tcatttagaa gaaattattg
    27841 atgaatggat tgtttttcga gattctttag accggttatt ggaggagagc acaaatgaat
    27901 gaatatttga atgaagttgt ggatcatctt caagaaattc ctgaagacga tcgttttgat
    27961 ttgatccagt attatgagga atatttttta gattctggaa aaacattaga tcagatcatt
    28021 gatgaatatg gtacaccaaa gcagtttgcc ttaaaattaa aaatcagtta cttttcagaa
    28081 gaagaacaag cagaaaacga gttagtgaaa aatccaaaaa gacaaattcg cctgatttgg
    28141 ttaatcatta tcggtttatt tgcttctcct gtcctcattc cactagcact ggggtttata
    28201 ttggttattg ggggactatt ggttgcttta ctagcgctca tttttagtat ctatgtttta
    28261 tgtatcagta tcttaggtgt tggcctattc atgatcatct caggaatcag tgtgtttgga
    28321 caatcgattc tgagtggatt attctttatc ggtgtcggtc tgttcgccac aggaagcgca
    28381 gtatttattt cgccactgtt gctgaaagga acaaaagggc ttttttatgt catgatgaac
    28441 tttgttaaat ggatgggacg acgttttatt acaaaaagag atctgcattc agcgggcgtt
    28501 tgaaggagga cacataaatt gagattgaaa cattttttga ttaccggtat tggtctgatg
    28561 cttactggtg gcctcctagc aggtgcaact tatacattag gcgctcaaaa gagtctgact
    28621 tgggataatg gtcctcggtt gatcgatatg gttactgaga caaaaaaaat caaggatgca
    28681 aacaaaatcg tcatccatgc agaaaatcaa acagtttcgg tcatacgcgg attggatttt
    28741 gagataaaaa cgacttatga taagacagaa aagccagaaa taaaggagaa aaatggcgtg
    28801 ttgactgtga atgcagtcaa aaaatcaaca ggtgcaatca ttagtttaga agacacaagt
    28861 gcacaaatca ctattgttgt ccctgcagat catgaattat ctgaattgac aatcgaaggg
    28921 aataatagtg caattgatat caacgaagta tcaatcaaaa aagtgaatac taagacacat
    28981 gatggctggg tatcgttcaa tgaatttaca ggaggaacaa taactgcgaa agatgaatta
    29041 ggctcacttc gactagatga ggccaatgtg gataacttga tcgtcacagg tgaaaacagc
    29101 aacttccatc tagaagacag tttgatcagc aaagaaggaa aagtcatcct aaacggtggt
    29161 aatttatctt tgcatgagat ggaaaacagt ggctatacta tccaaacgtc tggtgaatct
    29221 tatattgaaa aagactacca gccaataaca aatactttgt tagaacaagg acagaaaaag
    29281 ctaaagatca ctgctaaaga cacatcgatc aatattacga cggatcaaga ggacaatgaa
    29341 acagattgat cctgtactca actggatatt ttaagaaaaa acagcaaaga tccttccaat
    29401 ctttgctgtt tttcatcgct taacgcacat aactatagta aaataagaaa gaaaatatct
    29461 aaaaagaaaa cagggtgaaa gagtatatga aggtagaaga aggtcaaaga gaaaagttaa
    29521 agacagaaat ggaaagatta catatttata tcactcaact aagccaaacc ttctatgatc
    29581 cagacaaaga aaaagtgatg gttaattacc cgaacaattc agaaggtcgc caattagagc
    29641 aagtgtacca tgaagttttc aaacatttat tgacggtgaa gaaagagctg gattattatt
    29701 ctttaccgat tatcgataca ggaatattga agtatgatgg gaagaaggaa cgatttatct
    29761 ttaaatctgt tcgggaagat ttgcctcttt cagcagggat ggatctagag gtcttggtag
    29821 aagactattt tacagaagaa aagcactggg ttcgaacaaa attggattat ttaccgcagg
    29881 cagccggagg gacacaggca agcggttggt acatcactga agacaaagag ttagaactag
    29941 aaggtgtaat ggcgcgcatt cgaaaaaaaa ttaaaaaagt aacattagat atttattgaa
    30001 ggataaagga gcgcaggaag tagcatgaga gaaaaaagag cattttatat caatggttat
    30061 gcagggattg tcggattggt cgtattagct ttagttggat tgtttttctt ctatttaggc
    30121 atgtggcaag cgaaagtttg ggcacttttt ttaagtattt ttctttggtt gatcacgtta
    30181 ttgttgttaa gttcggcaac tgtagtcagt cctaatcaag caaaagtaat tttgtttttt
    30241 ggacaatatt taggtacgat tcgagaaaat ggctttttcc ttacgatacc tttggcacaa
    30301 aaaatgactg tttcgttgaa agttcggaat ttcaatagtt ctgttttaaa agtcaatgat
    30361 ttggatggaa accccatcga aatctcagca gtagtagtct ttaaagtcgt tgatacagca
    30421 aaggcattat tcgatgtagc gtattatcaa gattttgtag aaatccaaag tgagacagcc
    30481 attcggcata tcgctagcca atacccgtat gatacattca atgagaatga tttgacgctt
    30541 cgaggaaaca cgacggcagt gtctgacgag ttgcaaaaag agctgcaaga gcgtttagca
    30601 gtagcaggtg tcgaagtaat cgaaacacgc ttgaaccatt tagcctatgc aacagaaatc
    30661 gctagtgcca tgctccaacg tcaacaagca aaagccattt tgtctgctcg acaaaccatt
    30721 gttgaaggag ctgtcacaat cactcaaatg gccttagagc aaatcgaaga tggacaagaa
    30781 atcaatttca ccgatgatcg gaaagtccaa ttgatcaata atttacttgt ctcaatcatt
    30841 acagacaaag gaacgcaacc tgttatcaat acaggcgaca tgaaagaccg taagtgacat
    30901 actttttgta agataggaag aaggagttta ggacggatta ttgtcttgaa ctcttttttt
    30961 agttgtttta aagaaaatga caaaattgaa agaagaatga tagttgattc gaaggcagaa
    31021 ttgttcgctt ttttctataa tcagtatata aagtaagaga gaaggggaaa aagtgaaaaa
    31081 acttctgatc ggtctacttg ttttcatcgt tgtggtactt gcaggggtga aaatcgcaga
    31141 ttacgtagtt atgggtggag aagaatacta tgtacaaatt acgacagatg gtacaaaaac
    31201 agtttcaaaa tcagactctg gacaagaaac agtcaactat agatatatcc tgcctggcta
    31261 tacgaaagag ggtaaggaaa aagaactgga cttcaaggga caattgactc gaccgcttcg
    31321 taaaggagca tatttaaaaa tcacctggaa caaaaataaa ggtgtcactt cgtatgaaga
    31381 agtcgaaaaa aaagacgttc cgaaaacagc actggaaaaa ctaattaaag ggtagggaaa
    31441 gaaatgaaca aaatagtcga agtacagaat gtaacaaaag tatacggaaa aaacaatgag
    31501 aaaaagacgc aagcattaag cggcatcagc ttcgatgtag aaaaaggcga atttattggg
    31561 atcatgggcg cttctggttc tggtaaatcg acacttttga atattttatc cacattagat
    31621 aaaccaacag atgggcatat ccgaatcaat caaaaagatg tgaccacatt aaaaggaaat
    31681 caactagcag attttcgtgc gaatgagatt ggctttattt tccaagactt caatttatta
    31741 gaaagcttga cagcacaaga aaatatcgct gttcctcttt ctttacaagg cgtcaaacca
    31801 aaagaaatca agcaacgtgt ccaaaaaatt gcagaacgtt tatccatctc tcatattttg
    31861 gaaagctatc cttctgagat ttctggtgga caaaaacaac gggtcgccgc cgcacgtgca
    31921 ttgatcacac aaccaacgat tctattaggg gatgagccta caggtgcgct ggattccaaa
    31981 agtgcccggg atcttttaga tacgatggac gaattgaata caaaagatca tgtatcgatt
    32041 cttcttgtga cgcatgatcc gttttctgca agttattgcc aacgtatttt attcatcaag
    32101 gatggcggta tccatcaaga agtgaaacgt ggagatcaaa gccgtgattc cttctatcga
    32161 gaaatactat ctattcttgg aaacttggaa cagtaggggg agattgacta tgctttggaa
    32221 attatcactt actgggatca agagccgttt aagagactac ctggtgttat tctcaggatt
    32281 agttatggca tctgctattt tttacatgtt tgaatcaatg gcaagcaacg aagctttttt
    32341 gaaaagtaat acgatcgttg cggctacagt tatcattttc cgattcggtt ctgttttact
    32401 agggatcatc acattcgttt atattttata tgcaaattcc tttttgatga cgatgcggca
    32461 aaaagactat gcaatgttta tgatgctagg agcaaaaggc agaaaaatcg cacagatgat
    32521 tttttctgaa acattcttag tagggatcgc agctacttta gtgggttcag ctgtcggtgt
    32581 aggattgaca agtatcgtcc accgattatt agtggatcag ttagatctca atatttcgca
    32641 ttttacacct tttagtattc acgggttgtt gatcactgtt ttgttttttg ctgttttgtt
    32701 tttattagct gctgttgtca atgctttttc gattgtcaaa aaaccgatat tagcattgat
    32761 tcgtgcggat cagacaccaa caagaatcaa gcagcataaa ttcttgtttt tccttgaagt
    32821 agtactggga attgcttttc taggctgcgg ttactatatg atgaaacacg tggggaccta
    32881 tcaagtcttt ggtataggag tagccttagt tacgatcgta ttaggaactt atttcatttt
    32941 ccattctgtg atcattttct ttttatcatt actaaagaaa tcagaacaga tttcattgaa
    33001 aaaattgaac aatttcacat tgtcacagtt aaactttcgt attcgtgaat atacacaaat
    33061 gctctcaatg gtcgctatgc tgtttgcctt ggcactgggc gctttgacgg taggattagg
    33121 ttttaaaaat gaaattgcag acttgacaga aaacaattct ggatatgatc tagtgatgaa
    33181 taatcctcgg gcagaagatc agcaaaaaat caaagaactt tcaccaacac tttctgcttc
    33241 ttatactcaa aaagaagatg cgggaacgat ttactataat gcaagtgaat ttgcggctca
    33301 accattgatc atgataaaac atgaagatgg aacaccgccg aagatcacga aagaaaaagt
    33361 tcctgctgaa aaaatgaatg aactgactgt acaagaggaa cttcgaagct atgaattgcc
    33421 ggaacagcaa gaaaaagaaa tcaaggtagt cagtcaatca gaatttgatc aactgaactt
    33481 gccacaatcc actttacagc tagttcaggt aaaagacttc caagcaaacc tgaaaccaat
    33541 cgaaacactt gttgctcaaa ataaaatgaa caatccatct ttgcaaaaag tagagtacag
    33601 caaccagaaa tatgaaatgt atgaagtgta taatggtcta ttctctggtt ttgaatttat
    33661 gggattcttc ctaggtttag ctttcttgac catgcttgct agctgtttga tgttcaagat
    33721 cttgtcagga agcaagagtg acattgctcg ttatgaaatg cttgaaaaga taggaacacg
    33781 acgcgggttg cttaaacaat cgatccgtag agaagtaggc gtgttattct tagcaccagg
    33841 aatcttaggt gtagtccatg tcttattcgg attacaaatg tttggtctat tcatgcaaaa
    33901 tccatacaaa gatatttggg ttccgtttac gatcttcttc gtattgtatt tcatctacta
    33961 tgtactgacg acatggttat atactggaat cgtattgaaa aagagattgt gaaaaagctg
    34021 tcctgcatca agtaataaga acagccaagc aaaaatagct cctcctattt ttcgtttggt
    34081 tgggcttatt accgcagatg caagcttttg aacaccgttt gttcggaaaa agaggttgtg
    34141 acaatatttt tgtcacaacc tttttttcac ggtcttttat tagaatatag taaatttttt
    34201 ctcgttactc acggaataag ctgttaagaa aacggtttcc atgtatactg gaatcagtgc
    34261 aaatgaaaga aaagagggtg caaggaacat ggaaatcaat gaacaaaatt ttggcgaaaa
    34321 ctatcacttg attacgatca cgaatcaaaa tgggacatct ttgtctgtca gtgatcttgg
    34381 ggcacgggtt gttcattttc aaacaataat cgataatgaa aaacgagagt tgatcttagg
    34441 ttttgatgaa gcaaaagaat atctagaaaa agacccttat atcggtgctt caatcggacg
    34501 tatggctgga cggattacga atggcacatt caaattagat gatgaaacgt tcgaagtaaa
    34561 aacagacccg gacactggtc attgtttaca tggtggtgca cctagctttg aagccaagca
    34621 gtggcattat acagtcatca atggtgaaaa cgaagcatcg gtcattttct atcagactag
    34681 cccagacatg gaaaacggat ttcctggaac tttagatgta gaagtacggt atacgctgac
    34741 gaacgatgat acatggcgag tgacggtcca agggatcagt gaccgcaaaa cagtattcaa
    34801 tcctacaaat catgtctatt tcaatttaac cggtgatcca gcacagtcaa tcgacgaaca
    34861 tatactttgg ttgaatagcc gattatttgc tacgctcaat aaagatacaa cgcctacagg
    34921 agaagtagtt tcagtaagtg gcacagcatt tgacttccaa cgtcctaaaa aattaggtga
    34981 ggtctttgcc agtgattttc gccaatcaat gatagtgggc ggtatcgatc atccattttt
    35041 gttgaaaaaa caatctggtt tactaaatgc tgcggaattg acaagcccag atgaaaaagt
    35101 atcgatccaa gtaaaaacag atgcttcagg aatcgtgatt tttacagcaa attttggaga
    35161 agatggaccg gaaatgcgcg ggaataaatt agtaaatcat ggcggtatca catttgagac
    35221 tcaagaactg ccaggagcgg agcgacttga aagttttgga gatgtcactc tggaacctaa
    35281 ccaagtacgc gagtttgtaa cggaatacaa aataaatata aagaaataga ataaattaaa
    35341 aagggagtgt gacagtgtca catccccttt tta
//
LOCUS       DAFEML010000020        34694 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFEML010000020
VERSION     DAFEML010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.020"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            598..1287
                     /locus_tag="LP468_001211"
     CDS             598..1287
                     /locus_tag="LP468_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2080758.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="LP468_001212"
     CDS             1274..2482
                     /locus_tag="LP468_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2080759.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="LP468_001213"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="LP468_001213"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL2080760.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="LP468_001214"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="LP468_001214"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL2080761.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="LP468_001215"
     CDS             complement(6585..7280)
                     /locus_tag="LP468_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL2080762.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="LP468_001216"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="LP468_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL2080763.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="LP468_001217"
     CDS             complement(8479..8670)
                     /locus_tag="LP468_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL2080764.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="LP468_001218"
     CDS             complement(8691..9581)
                     /locus_tag="LP468_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL2080765.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="LP468_001219"
     CDS             complement(9568..10335)
                     /locus_tag="LP468_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2080766.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="LP468_001220"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="LP468_001220"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL2080767.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="LP468_001221"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="LP468_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL2080768.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="LP468_001222"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="LP468_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL2080769.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="LP468_001223"
     CDS             14906..15289
                     /locus_tag="LP468_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080770.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="LP468_001224"
     CDS             complement(15457..16215)
                     /locus_tag="LP468_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL2080771.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="LP468_001225"
     CDS             complement(16233..17051)
                     /locus_tag="LP468_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2080772.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="LP468_001226"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="LP468_001226"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL2080773.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="LP468_001227"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="LP468_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL2080774.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="LP468_001228"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="LP468_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL2080775.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="LP468_001229"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="LP468_001229"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL2080776.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="LP468_001230"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="LP468_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL2080777.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="LP468_001231"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="LP468_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL2080778.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="LP468_001232"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="LP468_001232"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL2080779.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="LP468_001233"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="LP468_001233"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL2080780.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="LP468_001234"
     CDS             27093..27392
                     /locus_tag="LP468_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL2080781.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="LP468_001235"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="LP468_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2080782.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="LP468_001236"
     CDS             27980..28216
                     /locus_tag="LP468_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL2080783.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="LP468_001237"
     CDS             28359..30332
                     /locus_tag="LP468_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL2080784.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="LP468_001238"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="LP468_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL2080785.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="LP468_001239"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="LP468_001239"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL2080786.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="LP468_001240"
     CDS             33211..34503
                     /locus_tag="LP468_001240"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL2080787.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10571 a         6745 c         6858 g        10520 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagatcag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg taaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggatcaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggtggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccggcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agacattgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg gggaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatccgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaatccttga
    25441 aaactatatc gaacatcaac gcgaagtcat cacacgacgg acggtctttg aaaaagaaaa
    25501 agcagaagca agagcacaca tcttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgag gcaaaagcaa caatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gtacagccaa aggaatccca atcatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg tcagagggat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaaa atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaataacca tcaagactaa gtgtgtaagc
    26881 tagcaagaat aaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taattagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tagatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaatgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata ttgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaagaggtag tgaaagagac gtttagcctt attgccgata
    34621 ggctgtctct tgaacactgt ttattcagaa taagggactg tgacaaaaac cgtgtcacag
    34681 tccctttttc cgaa
//
LOCUS       DAFEML010000021        33815 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFEML010000021
VERSION     DAFEML010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.021"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(313..2205)
                     /locus_tag="LP468_001241"
     CDS             complement(313..2205)
                     /locus_tag="LP468_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080788.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="LP468_001242"
     CDS             complement(2202..3929)
                     /locus_tag="LP468_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080789.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="LP468_001243"
     CDS             complement(3945..4595)
                     /locus_tag="LP468_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2080790.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="LP468_001244"
     CDS             4799..5095
                     /locus_tag="LP468_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2080791.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="LP468_001245"
     CDS             5287..5907
                     /locus_tag="LP468_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL2080792.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="LP468_001246"
     CDS             complement(5999..7165)
                     /locus_tag="LP468_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2080793.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="LP468_001247"
     CDS             complement(7177..7530)
                     /locus_tag="LP468_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2080794.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="LP468_001248"
     CDS             7658..8680
                     /locus_tag="LP468_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL2080795.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="LP468_001249"
     CDS             8699..8860
                     /locus_tag="LP468_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080796.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="LP468_001250"
     CDS             complement(9119..9553)
                     /locus_tag="LP468_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080797.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="LP468_001251"
     CDS             complement(9663..11522)
                     /locus_tag="LP468_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2080798.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12799)
                     /locus_tag="LP468_001252"
                     /pseudo
     CDS             complement(11640..12799)
                     /locus_tag="LP468_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(13106..14530)
                     /gene="araA"
                     /locus_tag="LP468_001253"
     CDS             complement(13106..14530)
                     /gene="araA"
                     /locus_tag="LP468_001253"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL2080799.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14546..15244)
                     /locus_tag="LP468_001254"
     CDS             complement(14546..15244)
                     /locus_tag="LP468_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2080800.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15201..16862)
                     /locus_tag="LP468_001255"
     CDS             complement(15201..16862)
                     /locus_tag="LP468_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL2080801.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17080..18480
                     /locus_tag="LP468_001256"
     CDS             17080..18480
                     /locus_tag="LP468_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL2080802.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18732..19811)
                     /locus_tag="LP468_001257"
     CDS             complement(18732..19811)
                     /locus_tag="LP468_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2080803.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19897..20856)
                     /locus_tag="LP468_001258"
     CDS             complement(19897..20856)
                     /locus_tag="LP468_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2080804.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20868..22379)
                     /locus_tag="LP468_001259"
     CDS             complement(20868..22379)
                     /locus_tag="LP468_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2080805.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22401..22964)
                     /locus_tag="LP468_001260"
     CDS             complement(22401..22964)
                     /locus_tag="LP468_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL2080806.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22970..23833)
                     /locus_tag="LP468_001261"
     CDS             complement(22970..23833)
                     /locus_tag="LP468_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080807.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23847..24743)
                     /locus_tag="LP468_001262"
     CDS             complement(23847..24743)
                     /locus_tag="LP468_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080808.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24918..26207)
                     /locus_tag="LP468_001263"
     CDS             complement(24918..26207)
                     /locus_tag="LP468_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080809.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26179..27696)
                     /locus_tag="LP468_001264"
     CDS             complement(26179..27696)
                     /locus_tag="LP468_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2080810.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27894..28784
                     /locus_tag="LP468_001265"
     CDS             27894..28784
                     /locus_tag="LP468_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL2080811.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="LP468_001266"
     CDS             complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="LP468_001266"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL2080812.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29693..31165)
                     /locus_tag="LP468_001267"
     CDS             complement(29693..31165)
                     /locus_tag="LP468_001267"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL2080813.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31802..32164)
                     /locus_tag="LP468_001268"
     CDS             complement(31802..32164)
                     /locus_tag="LP468_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2080814.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32387..33139
                     /locus_tag="LP468_001269"
     CDS             32387..33139
                     /locus_tag="LP468_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2080815.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33279..>33815)
                     /locus_tag="LP468_001270"
     CDS             complement(33279..>33815)
                     /locus_tag="LP468_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2080816.1"
                     /translation="DLLAYQKYGPLVFCEEIKGKQASCVFIDREQSITEGLTYLKQQG
                     IKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAEKGKQAGFFFKELG
                     VDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTIDHHLEACGEMAFQL
                     FLTEKKDKVKIPYTFIQR"
BASE COUNT         9984 a         7037 c         5855 g        10939 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc tagatgaggc aacataagta tacggtcatt ttctaagaac tcttcttctg
    12061 gaaaatcagt caagtattta gccagatgtt gtttttccaa tgcttgcata acagcatatt
    12121 tatcaacaat ttcacttctt cctacattga taagtacagc atcttttttc attttttcta
    12181 tattcgcctg atcgatcaat ccttttgtat cttctgtcaa cggcagcatg actacgatgt
    12241 aatccgaggt agaaagaact gtttctaaat ctgcttgccg aacataatcc aactgggcat
    12301 cgcggataga ataacccaag acatccatcc ctaagctata gcaacttagc gctacttttg
    12361 tgcctatcgc tccaagacca agaagaccga tggttttgcc ttgcaattct cgtcccacat
    12421 aagcacttct tttgttttct gcctgttcta aaatattagg acctgttagt gtttgtacca
    12481 tacgacttgc ttcgattatc ggacgggaag ataagagcaa acagcacaaa acaagctctt
    12541 ttactgcatt agcatttaca cctggtgtat tcatgacgat cgtcccgttt tcagaagctt
    12601 tttcaacgtt gatcgtgttc accccaacac cagctcttga aattgctagc aaatctggtg
    12661 taagccattc atctttcact ttcgtactac gaataactat tccttcggct ggcaaatcat
    12721 ctattatttt gaaatattcc ccttgtaact tttctatctc ttgttctgga atagcatcaa
    12781 tcaaatgaac gtgatacata aaaccccctc cttactaaca agtatctcga aatttctgca
    12841 attagacaac tgtttaccat ttgacttcct agaagcaaaa agagcagtta gagcagagta
    12901 ggctgagtga taaaaataag gctatgacaa gttactgcca taagccttat tttcgagagc
    12961 aaaatattga gggtgagata tcttgataaa tggtgttccg ttagctgaca ttgataataa
    13021 gactaaattt caaaaaagtt gaaaagcaaa tttcgtcaat ctcttcttat ttcttaaaac
    13081 taagtggctt tttcacaacc tctttttatc taataaccac tgtttccaac tcaactaatt
    13141 ttgcccacgt ttcaatttga tctgttgtta gatttagcga gacaacggta tgatgaccgc
    13201 cacctgcctg aatccatgaa tggacacctt catggaaatt cggtttagtt ttccataaca
    13261 cacgtgcaac aggtaaatta ggtgcttcag tcgttggttc aaaggcttct acttcattga
    13321 tcagcagttt ataatgcgta ccgaaatctg ccatcgatac gactacccct tctcctgctt
    13381 tcccatcaaa tacaagacgc gccggatctt ctctatctcc cattgataaa ggagaaacaa
    13441 cgattcttgg tttcgtcgca gcaagcgtcg gatctacttc catcatatgg gattccaaga
    13501 ttgcttcttg gccactagct agctcgtaag tataatcttc catgaatcct gtatctttcc
    13561 ctcgagccat gattttcagc aaccgatcaa tcgctgcagt tttccagtcg ccttccccag
    13621 caaaaccgta tccttctgcc atcaaacgtt gtacagctag tccaggtagt tgtttcattc
    13681 catacaggtc ttcaaaatta gtcgtaaaag cgttatagcc tccttcttct aagaaacggc
    13741 gaataccgat ttcctgctga gcttgtactt ttacatgttc ctcccatgtc ttttcttcat
    13801 aatcaccata gtcgaaggta tacaattcct tgtactcttc aaataattga tcgacttctt
    13861 cgtctgatac gcgatcgatt acttgtacaa gatctccgat accaaaataa tcaacagtcc
    13921 aaccaaattg aatctgtgct tccactttgt ctccttctgt gacacccacg tttctcatgt
    13981 tgtcaccaaa acgagccact tttattccaa aactttcatt ataggctact gcaacatcca
    14041 tccaatcagc aatctctttt tggatctcag gtcgtttcca gtagccaacg acgattttat
    14101 tttgtttatt taatcgagca ttgatgaacc catattcgcg gtcaccatga gcggattgat
    14161 ttaaattcat gaaatccata tcgatcgttt tccaaggaat gctttcgtta tattgcgtag
    14221 ctaaatgaag caatggtttt tgtagaagct ttgtcccgcg gatccacatt tttgctggtg
    14281 agaaagtatg catccaagtg atcacacctg ctacttcttc tcgataattg acctctttca
    14341 tgatttttgt gatcgtatca gcagtaactg ctaattcttg aaggcggatt ggataaggca
    14401 attggccatt ttcattcagt tcatcgacca tttcttgtgc atgtttcttt acttctcgca
    14461 gtgcttcttc cccatataaa tgctgtgatc ctacaacaaa ccaaaattct ttttctccaa
    14521 tattcaacat aattagccac tccttttatt tgttttgtcc gtaatacgca ttttttccgt
    14581 gttttcgtaa ataatgttta tctaaaatcc gttgaggcag ctcttctgaa aatgaattga
    14641 gctgtctggt aaataaattc atcttgcata cttcatctag tacgactgcg ttcattaccg
    14701 cactttgcgc atctttcccc caagtaaatg gaccgtgtcc gtgtaaaagt acccctggaa
    14761 ttgctaaggg atcaattttg cgttctttga atgtttctat gataactttt cctgtttcat
    14821 attcgtaccc gctgtcgatt tcctgttgtg tcaaaaatcg agcacaaggt accgatccat
    14881 aaaaagtatc tgcatgcgtc gtccccatcg caggaacatc caatcctgct tgtgcccaga
    14941 tcgtcgccca tgtcgagtga gtatggacga ttcctccgat ttgaggaaat gaacgatata
    15001 aaacagcatg agtaggcgta tccgaagagg gattgagttt accttcaatg atatgattgt
    15061 ccaagtccac aacgaccatg tcgtctgctg tcatctcttc ataactgact ccgctaggtt
    15121 tgataacgaa atatcgtgtt tcaggatcaa aagcgctcac atttccccat gtatatttga
    15181 cgagtccgtg tttaggcaag tcaagatttg cttggtatac ttcttctttc agttgttcca
    15241 gcattttcta tcactccttt ttcttgcaat tgatgaatcg ctgttttttc aatgtcgatc
    15301 ccctcacggt aacgtctcat aaatatctga tagcctgcta tttcttctgc tgaaggtgtg
    15361 atggtgattc cttggtcttg tccaaacacg tcttctgcca agaagttttc taaagacttc
    15421 ccatgtcgat ccatcatata ggctgctaat aacgcgattc cccacgctcc accttctccg
    15481 gctgtgtcca tcactgtaac tggtgcctcc atagcagatg ctagaatccg ctgtccaact
    15541 tctggtgttt taaaaatccc cccatgcccc actaaacgat caatttggac attctcagat
    15601 ttcaatatat ccattccgat tctcattgca ccaaaagcac tggctaaatg gatccgcatg
    15661 aaattcgcta aatcaaaacg gctacctggt gtacgtacaa ataatggcct tccttcattt
    15721 actcctgtaa tgttttcacc ggaaaaataa ccataagaaa gtaatccccc gcaatccgta
    15781 tcgccttcta gcgctttgtt gaataatacc gtgaataatt tatctctgct tatctccata
    15841 cccaaagaat tggtaaattc ttcaaaaata ctgacccaag cattgatatc cgaagagcag
    15901 ttattcgtat gaaccatgcc tactagttct cctgaaggtg tagtgaccat gtcgatttcc
    15961 ggatggacat tttctagttc tttttctaat acgatcatag cgaaggcgga agtaccagcc
    16021 gaaatgttcc ctgtcccttt ggctacactg ttcgtagcga ccataccggt tcctgcatcc
    16081 ccttctggcg gacaaaccgg gattcctggt ctcaaatttc ccgtagggtc gatcagataa
    16141 gcccctgatt cgcttaactt gccagcttct tctcctgcta ctagaacttt aggcaaaatg
    16201 tgatccaagt caatcgctac gtgcgctttt tcgattaact gaccaaaaat atttttcatt
    16261 tcttgatggt aggttttcgt tgaaggatcg ataggaaaca tgcctgatgc atctcctacg
    16321 cctagtactt tctcaccagt aagctgccaa tggacataac ctgcaagcgt tgtcaaaaaa
    16381 ttaatttctt tcacatgttc ttctttattc aaaatagatt gatacaaatg agcgatactc
    16441 catctctgcg gaatattgta ttgaaatttt tccgttaata ttcgttctgc ttcttcagtg
    16501 attgtatttc gccaagtacg aaatggtact agtaactgtt ccttgctatc aaatgctaga
    16561 taaccgtgca tcattgcact gaacccaatc gacccgattg tcgtaagatt ctcgccatag
    16621 atttcgaata cttctgctgc catttttcgg taactgacgc gcagtccttt ccaaatatct
    16681 tctaatgaat aggtccagat accattttct agtttgtttt cccactcata actaccagcg
    16741 gcaataggag taaaagatga atcaatcaat acagctttga tcctagttga tccaaactca
    16801 atccctaaag atgtacgacc atctatgaca tctaacatac tttgcgcatt tacttccttc
    16861 ataatgattt aactccctcc ttctcgtcaa acctgatcaa accgtctttt tagtagcgct
    16921 tacaatgatt attgtatact tttgtacgta catgtcaagc agttatttac aagaatacaa
    16981 taaaaaacac ttgttttgta cgtacataag ttataaaatg aaattgctta caaaatctga
    17041 tcaaccgcct tctcgaaatt ctagaaggag agaatactta tgaaaaaaga aaaaaaagtt
    17101 tcctcatcgt ttatttattt ttttggcgca tttggcggca ttctatttgg atatgatatt
    17161 ggtgttatga ccggcgcctt acctttttta cagcatgatt ggggtttggc aggtaaagct
    17221 tctttgatag gatggatcac gtcttcggtc atgttaggtg cgatccttgg cggctcttta
    17281 tctggtcttc tttctgataa gcttggacga cgaaaaatga ttcttctttc tgcacttatt
    17341 tttatggctg gttctgtcct ttctgcatct gcccctcaca atggttctta ttttctgatt
    17401 gcagcaagga ttcttctagg tttagctgtt ggcgctgcat ctgccctagt tcctgcttat
    17461 atgtctgaaa tggctcctgc tagactaagg ggaagattgt cagggatcaa tcaagtgatg
    17521 attgcttctg gcatgctcct ttcctatgtt gcagattatt tgctaaaagg gttgcctgaa
    17581 acgatggctt ggcgcgtgat gttagggctc gctgctgtcc ccgcgctgat tttatttttc
    17641 ggtgttttag ctctaccaga gtcaccgcgt tttcttatgc aatctggccg cttggaagag
    17701 gcaaaaagag tattgaacta tattcggaca ccaaaagaag ctgaacagga attcgaacaa
    17761 atccagctga atgtcaaaca agaaaagaca accggaactt cttggcatac tttgttttta
    17821 gaaaaatatc gttccttagt cattgccggt attggtgtag cagtattcca gcaatttcaa
    17881 ggagctaatg ctatttttta ctatattccg ctgatcgtag aaaaagcgac tgggcatgca
    17941 gcgagcgatg cattgatgtg gccgatcatc caaggaatca ttttagttgc tggttctttg
    18001 ctctttttgg ttattgcaga caagttcaat cggcgaactt tattgaaaat aggcggtagc
    18061 gtgatgggac tttctttcat cctaccagct gttttaggaa ctgtactgga tgctcataca
    18121 aattcgttgt tgattctctt gtttttatgt atttatgtcg cattttattc ttgcacatgg
    18181 gctccactga catgggtaat cgtaggcgaa atattcccac tagctgtccg cgggcgagca
    18241 tctggcctag cctcttcttt taattggatt ggttctttcc tagttggctt gctttttcct
    18301 gtgatgactg cttctatgtc tcaagaaatc gttttcggca tttttgggat catctgcttt
    18361 ttaggggttt tatttattca agagatcgta ccagaaactc gtgggaaatc tttagaggaa
    18421 atcgaacaaa gtgcatctaa aaaaacttat cctaaacgta tttctatcca tcattcttaa
    18481 agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaaccgctt agtttccagt
    18541 cacaaggaac aatttcaaaa aacagcttct catgtttgat gaatattgtg acttgtgacc
    18601 agttggtagg agaacaccgt ttagtggaga ggtggtgaaa gaaacgttca gccttgagcg
    18661 atgacaaaag ctctcacaaa cattgcgacg agtaaccgta ggagcaataa gaggcggtaa
    18721 aaacccgtct cttatttttc gttttctttc actgtttccc gttcaactag tacaggttca
    18781 tagagaatat ttggctgtgc ctgtcctttt tcaatcgttg tgacgatcca ccgtgcggca
    18841 tcttgtccca acttttcttt tggatgcgtc aatgttgtca attttttatt ccctaaatgg
    18901 cttaaagaag aatcgtctgt tcctacgatc gataggtcat ctggaatatg atagccattt
    18961 tctgtcaact tatctagcat taaactagct atttgatcgt tatagcaaat gatgccatct
    19021 aaagcttgtt cttctttcaa ccgttgtact gttttttcag cgattgtttc tcgtgtttcc
    19081 gtggtgaaag taatgatatc ttccgtcaaa aaacgcacat tatactgttc acacgcgctg
    19141 ataaaacctt tcatcctgta ttttccttga agatcgtcga tttttgtgat gaacaacaga
    19201 cgctgatgtc ctttttttat caaatattct gctgccataa aaccgacttt cacatcatct
    19261 aaacaaatat aagaggcatt taactcttca taagcagcat tgatcatcac catcggaatg
    19321 ccttgttctc tcaaagcaac ataaagtgct aagtttgggt tatactgatt acttttcgta
    19381 ggctcaacga tcaaaccatc taccccataa gcaatcattt tcttcaaaca ctctttctcc
    19441 aattcgtgat cgttattcgt actggctaaa agcaatgaat acccagattc tcgtaattca
    19501 ttttcgattc ctcggataat cgacggaaaa atataatcag agagatatgt ggtgatgaca
    19561 ccgatcgttt ttgttctgtt caatggtgtt ttttctttct tatagctgtc atctacatat
    19621 gtgcccgacc ctttttcttt acgcagatag ccctcattta ccaacacagc gattgcttgc
    19681 cgaatcgtat gtctgctgac gtcatatatt tcttgcagct tgaattctga gggaatggtt
    19741 gtatttactt cgtattcctc acgaaggatc ttttgtttta tctcttctgc aatatcttga
    19801 tattttgcca tttgccttgc ccctttttat ttgtacgtac atatatcata acgagtctgc
    19861 aaggtttatt caagcaaaaa tcaaggtttc ttgtgctcat aaggcatacg gaacaggttc
    19921 accaaattct ggaaatcctt gctcattcca cgtaaagcat tgcgcgttcg cgtgccgatt
    19981 aggattgtct aacggatccc ctttttggtt cttctctggt cgagcatgat agatcaaaat
    20041 atcaaagcac ccgtcttctg aaaccgtaaa cgagttgtga ccaggaccaa attgcttatt
    20101 tttttcagaa gaaacgaata ctggctccga taatttatgc catgattctt ttaataaaag
    20161 attcttgtgc tcatcagccc acagcaggcc catggcatag ttttcatctg ttgcactacc
    20221 agaatacgta atgaatattt tcccattgcg agtaaggact gctggacctt catttactga
    20281 aaaaccccgt ttttcccatt catactcagg tatagaaagg aggatctgct tcccctttaa
    20341 cgtccaagga ttatccattt cggatagata aagattagaa ttcccagtaa tttcaggatc
    20401 ttgttgggcc cacacataat atagctttcc ttgagaagag aaagttgttc cgtctaaact
    20461 gaaagtttcc cttttcgttt ttatttgtcc cttttctatc caatctgtat tcattggatc
    20521 tatatgctga ttttcaagta cgaacatgcg gtgatgatga gattcatcac gtatagtttt
    20581 atgattgctt gcagcaaagt aaatatacca ttttccattg atataatgga cttcaggtgc
    20641 ccagatcaat tcactcatcg gtccttcttc atgagcctgc catacaatca ggcttgcagc
    20701 atgttctaat tcattcagtg actttgccct tcttaattca atcacttggt agcctggaac
    20761 cgatcctgta aaataataat aaccatctgt atgtttatat acccaaggat ctgcccgttg
    20821 ccgaacgata ggattattat aaagtgtctt catcataaca aatttcctca cattttcttt
    20881 attctaatta cattccaaga gtatttttct atccctacat ttaattcgtc atgtttttct
    20941 attgaaaaat agtttatttc aggttttatt ttttctggtt cttcacgtgt atttttgtcc
    21001 aacagatcgc tactggttaa tgtgtagtgc tctccttgat ctagcaaatt gaaatcatgt
    21061 tcaatcgtta tcttttgttg ttcatttgtg cgattgatca agaaaatagt cagctgattg
    21121 ccgttatcta cgatcacact gtccacataa ggaacatttt ttatcttttc acaatcataa
    21181 acagggcaaa tgatttgttg tttcaatact tgacctttag catatttcga taagtgttgc
    21241 atcacataat aagttggatt cctccatgct tgtcctttag catctgtcag tattaaaggt
    21301 attgtgttta ctaacaatga ttgacaacta atctttacgc gatctgcgtg tcgtaaaata
    21361 gccagcccta atgaaccaaa taataatgta tcttccatag taaagtaaca ccaatcgatg
    21421 ggactaccga cttcaaaatc cctatgtctt ttttccggtt gggcatgtac attccattca
    21481 tcaaacgcta gatacattgt tttctcactt ctcaaatatc cttttacata atcacaagta
    21541 gcaacgattt cttcaatttg acgatcgaat cgataagctt ttgcaaggta tgtcgctgta
    21601 tcatcacgct catttttagg aggtttagtc aagtcttctt catcatactt atcaatatag
    21661 ttatgcaaag ctaaataatc tacattctca taagcttctt ctaatgcgat acgatcccat
    21721 tcagggtacg atggtaaacg tggcgtagag cttccaacta agattgtttc aattgaatca
    21781 tccactaact tcatgacttt tgaggcttca tttgctaacc taccatattc ataagcactc
    21841 ttagccccca cttgccatgg accgtctagc tcattcccta aacaccataa tttaacgcca
    21901 aaaggctttt tttgcccatt ttttattctt aaatcactcc agaaggttcc ttttggaaaa
    21961 ttacaatatt ctactaaatt ttttgcttca tcaattcctt ttgttcctaa attcaccgtg
    22021 aatatcggtt tcgcttgtac atgactgatc catttaaaaa attcgtggag tccaaaagaa
    22081 tttggttcta tacctcgcca tgctaaatca attttttttg gtcgttgttc tttcctacct
    22141 acagtatcca cccaatcata accagatgta aagtttcctc caggatagcg aatgacacct
    22201 aattctaatt cctttacata agagaggaca tcttgtctaa acccgtcacc atcagctgtt
    22261 tcatggcccg gttcataaat ccctgtatag acgacacttc ccatatgctc aacaaatgag
    22321 ccaaacagcc gagaactgat ctctcctacc gtaaaatcct ctctgatttt tactttcact
    22381 tcttcgtcca acagctttcc ctacctttca tttcctatag tcaagataat agatacaagt
    22441 ttccatacgc caccagcaaa gataaaaata aaaggaggga aaagaaatat gagcagtaca
    22501 aatcctaata acaatacgca acaaagaata tttctcaaaa aatcaaaaaa tactttccat
    22561 gcactttgtt caaaaatttg taaaaatgtg atatctttgt tttcagaaat cacatatatc
    22621 caggataaaa gaaacatgga ataaataagt aaaactacat atccactaat tgaaagtacg
    22681 attgtctgtt cttctaataa ttgattaaca agaaaataaa taatgatcgt taacagacta
    22741 aggaacaagt tcttaccaaa atgttgcttt attccttgaa agaaaaaata aatgatattt
    22801 cctgatccct cacctttcca ttgcgccatt acataaaaaa cagcacatgt agcaggcacg
    22861 atagtaataa caggcaaaca cacgattacc cagagaatac ctaataagat gtaatcagaa
    22921 accacaatca actgtccata aagtttagtc tcaactattt tcatcttcct cactctttca
    22981 ttccagacat agctgttcct tgaacaaaat atttctgtgc aaaaatataa accactagta
    23041 atggcagcat tgaaataacc gttccagcca ttacaggtcc ataaaaagaa atgttctgcc
    23101 ctgtaaataa agctaaccct gctggtaaag ttctcatttt tgaactactt gtcaatatca
    23161 atggataaag caagtcattc caactattca tcagcgtgaa aatccctaat gataaaagag
    23221 taggtttgct caatggcaac atgattttca aaaaaatatt aaactcactt aatccatcaa
    23281 tgcgtgctgc ctcttccaaa gaatctggta aagtaataaa aaaggaacgc atcatgaaga
    23341 taccaaatgc agttgtcata cgaggaatga tcaaacctgc ataagtatca agcatgccaa
    23401 gcaaattgac ttcaataaat agaggaatca tgaagacttg gaatgggatc atcattgtca
    23461 gcaaaacgaa atagaacaaa actgattttc ctttgaaacg catacgagca aatgcatacc
    23521 ccgcaagaga atcaaagaat acagaagtga tcactgtccc tccagcaaaa atcactgtat
    23581 ttttgatgta atctaataaa gggatcgttg tccaaacctt aatatagtta tctagggtat
    23641 agctatctgc aaatattcta ggcggaaatg agataatgtc tttttcgtgt ttaaaagaag
    23701 aaataatcag ccacaaaaaa ggaaacgcaa taaccaacaa tataactagc atactaatcg
    23761 ttcgaatgat ttttttacca ctaactgctt ttcgactatt cacagtaact gtaatcgagc
    23821 tttctggtgc catacaggtt tccctcctat ttcatttgtt tttctttccg tgacatgtac
    23881 acattagtgg agatagctat agttgcaaca atgataaaca aaaccgaaga cagtgctgat
    23941 gcatagccca attcataagg tgctgtaaat cctcgactgt aaatatattg aacagctgtt
    24001 tctgtcttaa attgtgggcc accagcggtt gcaacatata cttggtcaaa cacttgcatc
    24061 gaaccaatca gattcgttaa aatacaaaaa cctaaggagg gaacgatctg aggtagcgta
    24121 atgttaaaaa actgctgtcg atttgttgca ccatccattt gagcagattc atacaaagag
    24181 ggagagattc cctgaatagc agtcaagaga atcgtcatag taacaccaaa attcttccaa
    24241 acagtcatga tggctaccgt cggcatagca agggttggat cgcgaaaaaa ttgagggatc
    24301 ggcaagccga cttgtgaaaa caagtaagga atcgccccta cattcggatc aagcaacata
    24361 gaaaaaataa tcgcaattga cgtcaatgaa caaataactg gaatgtaaaa tgtcgaacga
    24421 caaaaacgat tgaatctggt atttttagat aatgctactg ctgctaataa accaacgata
    24481 atttgtgttg gcgtttcgag tacggtgaaa tataaagaat gaatcaacga attaactgct
    24541 cgttcatcac taaatatacg tgtgaaattt tcaaaactta caaaatttct tgatgtaaag
    24601 aaaatattca aatctgtaaa actaatagca aatgttccta aaagcggtat gacagtaaat
    24661 aataataaaa ctaaaaaaga tggagttaaa aacaaatacg cagcacgatc aggacgattc
    24721 caatatttgg tgaatccgtt catatagtcc acctcatctt tcattttgat aaaatataca
    24781 atcttggttt aaacgaatct gaataagata tccgaacaat cgctgtgatt tttgcaataa
    24841 cacctatctg caaatactag gtcgatcatt cagatatctg tatcttgcca acagtctatc
    24901 ctgtataaag ttctgtacta tttttgcagt aattgattga tggcatcatc tgcatcgttc
    24961 atgagtgtct caggatcttc tcctgctaat aatttttcaa tcagtggatt gatgatatcg
    25021 ttattgatcg cagagatttg ggtaaaacct ggtaaatatg gctctgcata gtccatttgt
    25081 ttcgataatt cagatacaat aggatcattt tttacttctt catcttttgc tactgaatcc
    25141 aagtaggcag gaaaaccatt ttcgatactc cattttttac caatttcagt tgtattccaa
    25201 tatttcaaaa actcatagac agcttctttt ttattattat ctgtacttgc cggaatggca
    25261 tatcctacgc catctaaaat agctgttttt ttgtctgaat cactcccttg tggtaaggta
    25321 gtcacattat aatcaatctc gtttgctttc aatccgttat ttaaccatgg cccattgatt
    25381 tcaatggcta gttgaccagc attcattaaa ttgtccattt cggcgccaga aatcgattct
    25441 ggaccagtct tgtctacatg gatcattttt tggatcgctt ttaacgtttt aaggttctca
    25501 ggagacgcaa attcagactt agtataatca tcgttcacta atttaccgcc atttgctaac
    25561 atccagttat ataacggtgc agttccatcc ttattgaaga caaaacctga tacattttta
    25621 ctactatcag ttaattttgg tgccatttct gtcaattctt cccaagtagt aggtggttgt
    25681 tcagtatcta atccagcttg tttaaacaaa tcattattcc aatacatata catgccttgt
    25741 acctgcatgg ggacaaaata ctgtttacct tctacttcac ctaattcaat agccgtttct
    25801 ttaaaatcag atttatctac tccatcatat tcccagaaat cgtctaatgg ttgtaccgct
    25861 ccgttttcta catactgtgc aaaatctgga taatttaatg caataaagtc aggtgctttt
    25921 ttagaagaaa tcgctgtagg aagtttttca ttcaaattgg cccaagtcat gatatccatt
    25981 tcaattttga tgtttttatc atttgtttta ttaaattcat taacgatttc ttgcaatatt
    26041 tcaccatcag atgcagtaaa cccattccaa aaagtcaaag tcacttcttt atcagaatca
    26101 gattctgctg aacttccgcc accgcaagct cctaaaatac ctgttgcagc taccaacaaa
    26161 gagccaatta accatttttt acctttcatt ttttgttcct ccttcatctg ataaacgaca
    26221 tctgaccaca ttccaagata gcggtttcaa taaacaattg attttcccat cttcagcttt
    26281 tacatttgtt gaatgacttg gttttacttg ttcactttta ggaagattag ttgcttttgt
    26341 atcaaatcca ctcatttcag aaaaatcaat cactccctct aatgataatt cagacaagtg
    26401 aacagttaga ttcatttctt cttctccacg gttaactgca aatatgacaa gttctttgtc
    26461 atttattacg gctatacttt ctaaatacgg cacttcttca aaatcttccg tcgcatagtt
    26521 tgctgaacga atttgtgggc ttaacacctc tccttgtcca tacacagcag cttgcataaa
    26581 tggataatag atcgtctgtc tccaagcttc tccgtttgtt tctgtcctga ttggtgcaat
    26641 aacatttacc aattgagcaa gacaagcaat ctttactcta tctgcatgtt tcaataaagt
    26701 gattaataga cagcctaata gtaatgcatc ttcaaaatta tagttatctt ctagtaaagg
    26761 aggagcaatc tgccaaggcg ctgcttgctc atcttgttcc gctgaatgat accaaatatt
    26821 ccattcatca aaggacaggt tgatctgctt cttactatgt ttcttcgcct tgactgtatc
    26881 gcacatcgct gtcacttcag aaatgaaccg atccatgtct aaggaacgtg caagataatg
    26941 agaaagatca tttttttggt tgccataata ttgatgcaga gacaaataat ctatttgatc
    27001 gtacgcttga tcaagaactg ttaactccca atcaccaaat gtaggcattt gccgattcga
    27061 acttccgcat aaaaccacct caattgaatc atctacgagt ttcatcgcct tagccgtttc
    27121 ctctgctaac cgtccatatt cttccgctgt tttatgtcca atctgccaag gaccgtccat
    27181 ttcattccct aaacaccatg tcttaattcc aaaagggctc tcttgaccat tcgaacgcct
    27241 taaatcactc caataagttc ctttaggaaa attacaatat tcgactaaat tacgagctgc
    27301 atctactcca cgagtaccca gattgacagc catattgatt tcggccccca catgctgaca
    27361 ccagttataa aattcatgaa tcccaacttc attcgtttca attgtccgcc aagctaaatc
    27421 caaccttcta ggtctatttg ctatgggccc aatactgtct tcccaacgaa atcctgacac
    27481 aaaatttcca ccaggatatc taatcatggg aatgttcaat tcttttacca agtgaatgac
    27541 gtcttggcga aatccacttt tattagctga tggatgatct ggctgataaa tcccttcata
    27601 tactgctcgt cccatatgtt caataaatga actgtacaac cgcggatcaa ctttgcctac
    27661 acgcttgaca ctactaatca acattgtggc ttccataact gacctccttt aatttataca
    27721 tgaataatac acctcgttga aagcgttgtc aataatataa atgttaaact tacttatttt
    27781 ttatcgattt taattaacca aaatattaat aatgattaaa acaaataatt taatataact
    27841 tttattaaca aatatgttaa tatataagaa aaacctttta agaggtgata tatatgcaac
    27901 tacaaataaa cgaagaatcc ttaccggtat atgaagcatt agctagtaaa acaaggatca
    27961 agatcatcca gctactttcc aaaaaaaaga tgaatgtcaa agatttggca aaagaacttg
    28021 gagtgagcag tgctatcacg acgatgcacg tgaaaaagct agaggaagca aacatcatca
    28081 aaacagaaaa agtaggacaa caaaaaattt cgagccttcg tgtcgataaa atcgatatca
    28141 gttttccaga aaaaatattc aatgcttttg atacgaaaga aacatcgata cctattggtc
    28201 actatacaaa ttatgcaatt gaaccaacat gcggtttagc tacgatccat gattttatcg
    28261 ggaaagtgga tgaaccacgc tattttatgg atcctcgaag gatggatgcc cgcattctct
    28321 ggtttaccag cggatttgtc gagtatcagg cacctaattt tttaaataca gaggatacat
    28381 tggagatgtt ggaagtttct gtggaaattt cttctgaatt tcctttttca aatgacaatt
    28441 ggccttcaga tatcactttc agcctaaatg gtgtggagct aggaacatgg acgagccctg
    28501 gagattttgc tgatatccgc ggtaaatata cgcctgattg gtatccagat aatcttaatc
    28561 aatacggctt gctgaagacg atccgaatta ccaaacactt gacgaatatg aatggagaac
    28621 ccttgtcaaa catcacgatc aacgacatcc ctaaagagca agacacttgg catttgcgaa
    28681 tcgaagtgaa agacgatgcc aaacatgtgg ggggctgtac tttatttggt aaaggattcg
    28741 gtaattacga tcaggatatc aaattaaaag tttactacag ctgatatttt tcttttctat
    28801 tttataaaac aaaaacagcc aatccctatg aagggacggc tgtttttgct ttattgttat
    28861 ttccagaaat catccaaaac ggaaattggc aaatgtcgtt tatgttgtgt cttgttccac
    28921 catgcttcga ttttttcttg tgcttgagcg ggaacttctt ttccttctag ataatcatca
    28981 atttcattat atgtgacacc tagtgcgact tcatctgcaa tcattggttt cccatcttca
    29041 agatctgcag tcggaatttt tgtgtataat ttttccggtg cattcaatgc ttgaagcaat
    29101 tgtttccctt gtcgtttgtc caaacggaat aatggcaaaa tgtcggctcc accatcacca
    29161 aatttcgtga agaatccagt aatgttttct gcagcatgat ctgtccctaa tacggctcct
    29221 gctctttctc cagctacggc atattgcgta atcatacgtt gacgtgcttt gatatttcct
    29281 ttgttaaaat cgctgattcc cacacctgct tcgcttaata cttgtacttg tgcatcaaca
    29341 gctggtttga tatttactcg cagactaaca tcgggctgga taaagtcaag agcagctttt
    29401 gcatcttctt catctgcttg ttcaccataa ggaagacgaa cagcgataaa ttgatagttt
    29461 tcatcttttg tttcttcacg catttcttcc atcgttagtt gcgccaaacg gcctgctaaa
    29521 gtagaatctt ggccgccgct gatacctagt acaaaagttt taagaaacgg atattttttc
    29581 aaatatgctt tcataaagtc aatactttta cgtatttctt cttttggatc aattgttggt
    29641 ttgacaccta attcattgat aatttctgtc tgcaggctca tttattctcc tcctatgctt
    29701 ctgtatgaag ttctgctacg ctttttttca ttcgttccat gatagccatt ttatggttcc
    29761 agcattcagt agacagatcg actgggtatt tttgcggatt caagtctcgt ttatactctt
    29821 cccatagtga atctagattt tcttttgtat attctttgat ttcgtttagt gcaggtaatt
    29881 cgtaaactct ttttccttcg ataaagatat cttgtaaaac tgggcgagct gtaaagtctc
    29941 gaacagtttt attgataaac gtatgcactg gatggaacat gaagatagct tcttcttctc
    30001 gagggtcttc atcccataat gtcacgtagt ctccttcaga tttcccatca aaatttcgag
    30061 tgatgcgcca cacttgtttt ttccctggag tagttacttt ttctgcattg cttgataact
    30121 tgatcgtatc catcattttt ccttcatcat cttcgatcga tactagcttg aatactgcac
    30181 caagggctgg ctgatcatag gctgtgatca attttgtccc aacaccccat acatcaattt
    30241 tagctttttg catctttaaa ttcaaaatcg ttgcttcatc caagtcattc gaagcataga
    30301 tttttgcttc cgtaaatccg gctgcatcta attgttcccg aacacgctta gatatatagg
    30361 ccatatctcc actgtcgatg cgtacgcctt ggaagttgat tttgtcacct aattctttcg
    30421 ccacgcgaat cgcacttggc acacctgatt tcaacgtatc ataagtgtcg actaagaaca
    30481 cgcagtcttt atgggtttta gcgtaggcca taaatgcttc ataatcattt ccataagatt
    30541 ggactaacga atgagcatgg gtcccgctag ctggtatccc aaatatcttc ccagcacgta
    30601 cattgcttgt tgcatctgct ccgccgatat atgccgctct agttccccag actgctgcat
    30661 ccagttcttg tgcccgtcta gttccaaatt ccaatagtgg atcttctccg atgacagatt
    30721 tgatacgagc tgcttttgtc gcgatcaacg tttggaaatt gaccatattc aacagtgctg
    30781 tttctactaa ttggcagtgc gctaaaggcc cttccacttg gattaatggt tcatttgcaa
    30841 aaactagttc tccttcacga gcagaacgaa ctgttgcttt aaattcaaaa ttttgtaaat
    30901 actccaaaaa accttcagga tagacttcta atccacgcaa gtaagcaata tcggaatcat
    30961 tgaacgtcag attctctaaa taattgacta accgttccaa tcctgcaaaa accgcgtatc
    31021 cgtggttaaa aggcatttct cgaaagtaac attcaaaaac agcatgtaaa tcagctcgac
    31081 ctaattccca gtatgtctgc atcatattga tttgatatag atccgtatgc agcgtcaaac
    31141 tgtcgtctgg gtaagtatta ttcatcttgt attactcctc ttggcaagtt ttcatttcct
    31201 acccattata acaaaaaaaa ttaataggaa aagaaatctt ccattttttc tgaaaaagca
    31261 catgttttac ggatatttct tgctaaaaat gaactccatc tgctaaaact atcctttctt
    31321 attggtattt aacctaaacg agaaagaata cttattttat tcaatgtatc cgagacacga
    31381 agaaattagc gttttctatt tttcttactt gataaaataa gtagattttc ctactacaat
    31441 cgtagccgtt aagataccga tgattgaaca aatataacca aatgtctcta caacataatc
    31501 aatggcaaaa gtttttgaag caataatacg tctttccttt tttgcttctt atccccaaag
    31561 aaacggatat aacttattat gtattgaatt tttttggaaa ggcgaattat gacaagatat
    31621 accttgcgtt gaaaaaactc gcggaaaaaa tatcacacgt ttttaaaaag atacaaagta
    31681 agaaagcagc tgtcaataga atggaaacaa aaatggcgag acatcaatca gtctcgcctt
    31741 gttttttatt gtatacatta gatatggagc aggttaccat aaagatgatt attagtcgtt
    31801 attaaataga atccttcgta tttttttgtt ctatcactac aatatcttta tttggacgtt
    31861 tgaattgtat tccggcacgt tctagctcct gtttcactcc tacatggact ttgacatctt
    31921 ctcgtgtcat ttttaaaacg tgatgaatcg catagtcgat ttcttgcctt gtgatttttt
    31981 tcttcgtatt gatcatcacg acttgctttt tatcatatgt gtctaccaat agcagttgtg
    32041 ttcgatctaa cgaaaataat ttgtaataat taatagccgt attcccaaaa aagaattcca
    32101 ctactttagg ataaaatgtc ttaatattta aattactatt cacaggtgtt tcgattagct
    32161 tcatctcatt cctcttttct atatagtcga tttagatcca atcttaagtt atgttaccat
    32221 ctttcctagc attaaggaat cggttacaat tgaaccttta aagacaaaag gatttacctt
    32281 ttatcactta atagtataac ataatttcgt gagaaaaaaa tacaattttt tcttgaccat
    32341 ctcgttacgt aaaggattat gcttacattt gtcaggagga aaaataatgg agtacacaat
    32401 aaagaaaatg tcagagatat caggagtcag tccgagaacc ttgcgctttt atgatgagat
    32461 tggactgcta aaaccagcta ggatcaattc ttcaggttat cggatttatg gcaaaaaaga
    32521 agtcgatcgt ctgcaacaca tcttatttta tcgaacaatg gcattcaagt tggatgatat
    32581 ccaagaggtc ttagacaatc catcttttga ccaccagaaa gctttaatca agcatcagca
    32641 aatgttgctg gaaaaacggg cacaaatcga taccctcttg acaactgtcc aacagacact
    32701 tgatatgtac gaaggaggaa gaaaaatgag tgacaaagaa aaatttgaag ggtttaaaca
    32761 acaaaagttg aaagaaaatg aagaatccta tggacaagag attcgacaaa aatacggaaa
    32821 aaaaaaggtt acagcatcca atgaaaaatg gatgaatatg gataaagaaa cgtatgaaga
    32881 aatgcaaact gttgaaaagc agatgttatt tgatctcact ctttacttaa aagaaccaga
    32941 agatgaaagc ttagcagacc gtatcttcca agctcataag aagtggttct cttacagctg
    33001 gcctgaatat cagccaaaag cgcataaagg actaggaatg atgtacgaag ccgatgaacg
    33061 gttcactgca tattatgacg agcgaagtgg tcatggtgca gcaaaagctt taaatgaaat
    33121 tatccaaaaa aaggcgtaat cttttacatg atccaacaaa aaagtacacg taaaatgacc
    33181 taataacaaa acagcagaca cccaagttag atttttatgc taacttttgg tgtctgctcc
    33241 attctttcac aagttttttc atcctacttt aaatatattc atcgttgaat aaacgtataa
    33301 ggtattttca ctttatcctt tttttctgta agaaacaatt gaaatgccat ttctccgcaa
    33361 gcttccagat ggtggtcgat ggttgggaaa ccaagaagct cgctgatcag caaattatcg
    33421 cgtccaatca ccactggtgt cttatcttgc agatagcttt gcaagatgcc tgctgcaacc
    33481 atatccgaat ttgtaaagac accatcaact ccaagctctt taaaaaagaa gcctgcttgt
    33541 tttcctttct ctgcatctat acaatcccaa aaaacaagtg attcatcaaa agatggaaaa
    33601 agttgatgac atagctgcaa agtgattttt gagttataac ttagcctgcc acttcgcccc
    33661 aacgtgatgc ccaattgctt tataccttgc tgcttcaaat aagtaagacc ttctgtaatt
    33721 gattgttctc gatcaataaa gacacagctt gcctgttttc ccttgatttc ttcacaaaaa
    33781 actagaggtc catatttttg atatgccaat aaatc
//
LOCUS       DAFEML010000022        32497 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFEML010000022
VERSION     DAFEML010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.022"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..453)
                     /locus_tag="LP468_001271"
     CDS             complement(<1..453)
                     /locus_tag="LP468_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2080817.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(880..1155)
                     /locus_tag="LP468_001272"
     CDS             complement(880..1155)
                     /locus_tag="LP468_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080818.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            1449..2264
                     /gene="thiD"
                     /locus_tag="LP468_001273"
     CDS             1449..2264
                     /gene="thiD"
                     /locus_tag="LP468_001273"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL2080819.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(2593..4044)
                     /gene="cls"
                     /locus_tag="LP468_001274"
     CDS             complement(2593..4044)
                     /gene="cls"
                     /locus_tag="LP468_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2080820.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            4385..7051
                     /locus_tag="LP468_001275"
     CDS             4385..7051
                     /locus_tag="LP468_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2080821.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            7415..8167
                     /locus_tag="LP468_001276"
     CDS             7415..8167
                     /locus_tag="LP468_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2080822.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(8189..9343)
                     /locus_tag="LP468_001277"
     CDS             complement(8189..9343)
                     /locus_tag="LP468_001277"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL2080823.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            9528..11969
                     /locus_tag="LP468_001278"
     CDS             9528..11969
                     /locus_tag="LP468_001278"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL2080824.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(12299..13003)
                     /locus_tag="LP468_001279"
     CDS             complement(12299..13003)
                     /locus_tag="LP468_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080825.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(13190..13435)
                     /locus_tag="LP468_001280"
     CDS             complement(13190..13435)
                     /locus_tag="LP468_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080826.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(13452..14303)
                     /locus_tag="LP468_001281"
     CDS             complement(13452..14303)
                     /locus_tag="LP468_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2080827.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            14469..15473
                     /locus_tag="LP468_001282"
     CDS             14469..15473
                     /locus_tag="LP468_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL2080828.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(15714..16070)
                     /locus_tag="LP468_001283"
     CDS             complement(15714..16070)
                     /locus_tag="LP468_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2080829.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            16438..17625
                     /gene="tuf"
                     /locus_tag="LP468_001284"
     CDS             16438..17625
                     /gene="tuf"
                     /locus_tag="LP468_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2080830.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(17813..20404)
                     /gene="mprF"
                     /locus_tag="LP468_001285"
     CDS             complement(17813..20404)
                     /gene="mprF"
                     /locus_tag="LP468_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2080831.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(20430..21191)
                     /locus_tag="LP468_001286"
     CDS             complement(20430..21191)
                     /locus_tag="LP468_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2080832.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            21469..21990
                     /locus_tag="LP468_001287"
     CDS             21469..21990
                     /locus_tag="LP468_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL2080833.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            22049..22909
                     /locus_tag="LP468_001288"
     CDS             22049..22909
                     /locus_tag="LP468_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL2080834.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            23094..25409
                     /locus_tag="LP468_001289"
     CDS             23094..25409
                     /locus_tag="LP468_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2080835.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDHKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            25591..27432
                     /locus_tag="LP468_001290"
     CDS             25591..27432
                     /locus_tag="LP468_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL2080836.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            27456..28565
                     /gene="rpoD"
                     /locus_tag="LP468_001291"
     CDS             27456..28565
                     /gene="rpoD"
                     /locus_tag="LP468_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL2080837.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            28785..30884
                     /locus_tag="LP468_001292"
     CDS             28785..30884
                     /locus_tag="LP468_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2080838.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            31080..31943
                     /locus_tag="LP468_001293"
     CDS             31080..31943
                     /locus_tag="LP468_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL2080839.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTKEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            32048..>32497
                     /locus_tag="LP468_001294"
     CDS             32048..>32497
                     /locus_tag="LP468_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2080840.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEK"
BASE COUNT        10804 a         5679 c         6714 g         9300 t
ORIGIN      
        1 tatataataa tttaaaaatt catcatctaa atccgtagaa ttttctagat tgcttaccca
       61 tgtaaaatcg ttatagacag atttcagttg acttctgcgc cattgtacag ggataaaaag
      121 acgcatgcta tcttcattga atccgactaa taatttcttt ccgtcagtaa tgatgggacg
      181 ttgtaacaaa gtaaaatgcg agacgatcag atcgacaagc tctgaggtcg tacattggtc
      241 gatttggtct ttcaaatttt tataatcaat cgagcgttta gctaatagat cgtcaaatcc
      301 gttttctgtt aatgacaata aataaaatat ctctttcctt gttaaaggct gtttaggtgt
      361 gaaaattcgt tctctgtaag gcatttgatg gtctttcagc cagtttgcca tcagatggta
      421 actatgtgtg cgagaagaat agatcgtaag cataaaaaaa ctccttaaat agtccattaa
      481 tttgttagat ctgttgagat aaataatagg taaggagctg tgcataagca ttgatcaaaa
      541 caacccaaac atcattagaa ataactttct aaagtcttaa acttgcgacg agaaacaact
      601 agactaatag aaaaaatgtc ttagccattt ggcttcctgt ttgttttttt gcttatgctg
      661 cagctcctcg ggaaagggtt ctaacaattt gaagaaggtt gatgattgat ctagtttaaa
      721 ttgtgtgaaa tttgaaatct ggtgttttta ctagatgaat cacctaacaa ctatgattat
      781 aacttataga acttctgttt tgcattcggt tttgttatag ttgttataaa gttttatttt
      841 attacagaac atttttaatt aataaagaac agttagaagt taaaattgct gattcacata
      901 gagtttatga cttcttggaa attctttttc aatcagtttt ttcatctgtt tatgaaattc
      961 ttttttttca gtaaacataa aggtttgggt atcgtaacct tcttcatgta ggaaatagat
     1021 tattcctttt tctgtgtttt gcgtataagc ttttatactc ctgtcttttt tgaaagaaca
     1081 gatcgtatag ccatctattt ggtctggtag tcgtttgatt ttcttcaaaa tgactttttt
     1141 atcctcaagt ttcatttttt tcacctgact ttattttttt catatggaaa tcatagcgcc
     1201 tttggttata tgaaaacaag aaggatactg aaatatatat aaatcaaata gtggttattt
     1261 attattagaa tagcgaatac aaataaacga ccactatttt ctgatttatt gcaaatgttt
     1321 tttcaaataa atttgattac caagaaaagg tagtggtata tttactgagg gatactttga
     1381 aaaacatatg atagaaacag taacagtatt atgaaaaatc tttttataaa aatggaggaa
     1441 tcgatttgat ggaagatcag tatgtacaag caatgacgat cgcaggatca gatagcgatg
     1501 gaagcgcagg gatgcaagca gatatgcata cattctttac aagaaatgtt tacggtgttt
     1561 ctgtcatgac cgcatgtgtt gcaggtaatt cttacggaat cggagcaagt gtgacattgc
     1621 caacagattt tatcgacaaa gaatttgaac tgattgcgaa ggactttcaa atacgtgcag
     1681 ctaaaacagg tatgctagca gattcaaagt tgattgagac agttgtaaaa aattaccaaa
     1741 aatatgattt tggaccatta gtcgtggatc ccgtaatcgt aacgaaacat ggaaatcttt
     1801 tactagaaga atctgctttg caaagcttga aagaaaagct tgtccctttg gccgaagtac
     1861 tgacacctaa tttttatgaa gcagaaaagc tgactggacg gacattagca gctgaagaag
     1921 attttgtgca agcagcaaaa gaactgcaag atatgggtgc aaaaaacgtt atgatcaaag
     1981 gacatcatgc taaaaatgcg cagcaagaaa cagtcaatga ctacgtattg ttcgaatcag
     2041 gaaaatcatt ttggttaaat gcaccatttt atcctaccga ccggatcaac ggaactggcg
     2101 attcgctatc tgcatgtatt gcagctgagt tagcgaaagg aaaaacagtt gaacaagcga
     2161 tccgattggc aaaagactat gtaaaccgtg caattcgtga agaaataaat gtagggcaca
     2221 aatatggccc catcaatcat tgggcagctg gtgaattaga gtaaaagaaa gaagttgtga
     2281 aaaagttgcc ctgcatcaag taataagaac agccaagtaa aaacagcttc ttatgttttt
     2341 aacttggttg gacttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggtc
     2401 gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag cttctcatgt
     2461 ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt tgttcggaag
     2521 aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt tttctctact
     2581 tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct tgaataatag
     2641 ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg tctcatcttc
     2701 tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag cacttgtttc
     2761 aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc agatttcatc
     2821 atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga tttgtacatt
     2881 ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag gatgatccgg
     2941 tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt ttaaagcagc
     3001 aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt ttttagcaga
     3061 agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg gtccgcttga
     3121 aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt ttttaaagaa
     3181 ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc agtctgttaa
     3241 gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg tatcgcgcca
     3301 atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac caccggtata
     3361 actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca atcggaaacg
     3421 aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt tgattagacg
     3481 attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata ttcgaacttc
     3541 cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga tattatctgt
     3601 cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat cttgaagcag
     3661 tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc ttgtcagcgg
     3721 catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat cgcccatgtc
     3781 aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta attctttcaa
     3841 gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga aaaataaata
     3901 taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc aaatggctgc
     3961 tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta atagataaag
     4021 ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata acattagtat
     4081 agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct ttcatgaaaa
     4141 tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag gatattagta
     4201 cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat atcaacagta
     4261 agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac aaatgcgtat
     4321 ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa atgggggatg
     4381 aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga tcgactcgtt
     4441 gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga aggaaaaatt
     4501 agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt ggaaattgtt
     4561 cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac tgattcagat
     4621 ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt tgaattctat
     4681 aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga aaaacctttc
     4741 agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg caaacgaact
     4801 tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg atggacgttt
     4861 actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt cgacttctgc
     4921 agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta caaatatggt
     4981 attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt caactgggaa
     5041 taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc aagtcactcc
     5101 gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt tggcattgtc
     5161 tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta caggagatat
     5221 gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag ctgctattcc
     5281 agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata aaatggcaaa
     5341 acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga caagtatcat
     5401 ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg actacttttt
     5461 aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag ctgacgaacg
     5521 tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag acggtactaa
     5581 attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa accagcctta
     5641 tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact cagatcgaaa
     5701 attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta aaggcggacc
     5761 agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg ttccgatgac
     5821 ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac gcgcattacg
     5881 tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg aagatgaaga
     5941 cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg aagtgactca
     6001 ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg gtgaccacaa
     6061 aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa acctggcttt
     6121 gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt tagaaaaagt
     6181 cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg cttggcaaaa
     6241 taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag cattgaaaca
     6301 agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg cagcagcgat
     6361 ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag gacgtaatgt
     6421 gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag gtgcgatcat
     6481 tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat tacaactgtt
     6541 gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag aaaaagctga
     6601 acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta cggacaaaac
     6661 attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct ttgctcaatg
     6721 gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa cattgatttg
     6781 gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta tccaagcagg
     6841 gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc tttactgctt
     6901 aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg gattgacaga
     6961 agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa tcactaaatt
     7021 gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt gagcctgccg
     7081 tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt gttgaatatt
     7141 gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt tgtaaaatca
     7201 gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg aaagagggac
     7261 tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa agccaatcat
     7321 tttattattc atcaaaagag atagaataga taaaagagga gaatgattta ttccgaaaag
     7381 tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat gggatgaatt
     7441 tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg aagatgtaaa
     7501 aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg ttgctggagg
     7561 atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga tcgatttttc
     7621 ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc caaatgtttc
     7681 ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg aaatggtttt
     7741 tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga tgaaaaagtc
     7801 aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt tttatcctat
     7861 cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg taatggatca
     7921 atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt ttacttattt
     7981 tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt acgcaaaaga
     8041 tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa tccttagtac
     8101 gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa cctttcacga
     8161 ctcgtgaagg gttcttttta tgattttatt atattttgta gtaacgaata tcattttcga
     8221 tctttgtaat cgaaaaaggt acatctgaag tatattctgc acattctccg tgttcaggaa
     8281 gcgtctcact gaaaatcgtt tcatattcgt caacagtgat ccgtgttcga gaatctagca
     8341 tctcttgatg agattgtgcg aagagatatt cttgatagtt ttcttccaga taacctgtaa
     8401 aaaattcact tactgcacca gaaccgtagc tgaatagacc gatgcgatct cctggctgta
     8461 gtgatttcga attttccagt agagaagtta gccccaggta taatgaacca gtgtaaagat
     8521 taccgattcg tcggctgtaa cggatgcttt cttcatagcg agccataaga cgttcctgat
     8581 tttcttcgtc tgtttggtct aatacgcttt gcaatgcctt ttttcccatc ttagtatacg
     8641 gaatatggaa agcaatcgcc tgataatctt cgagtcctcg acccgacaat tctttatgtc
     8701 gattccaaac tttttggaat gattcgatat acgtagaatt agataaagga ccatcaacaa
     8761 caggaaattc gctataatct ggacgccaga aatcatagat atcttctgtc agaaatacgc
     8821 tgtcgtcttc aatcgataaa atacgcgggt tttgagtgat catcatcgca acagcaccga
     8881 caccttgcgt cacttcacca ccgcttgcca agccgtaacg agcaatatca cttgctatga
     8941 ctagtacttt tcgttctgga tgatttttga catattcttt cgccatgtgc aaagctgcgg
     9001 tgccaccgta gcaagcctct tttacttcaa aagaacgagc aaaagattgg attttcagta
     9061 aatggtggat aattaccgca ctcgcttttg aatgatcaat cccggattct gttccgacga
     9121 tgaccatgtc gattagctca cggtcttttt ctgttacgat tttgctggca gcatttgctc
     9181 ctagtgtaat gatgtcttca tttgcacgat tgactgccat ttggtcttga ccaatcccta
     9241 tatggtattt tgcaggatca tccccacggc tttctgccaa ctctgtcata tctaaatata
     9301 aattaggaat aaaaaaggaa agacgatcaa tccctatttt catttcaaca cctctttact
     9361 tatgataaaa aacttacttt actaaggtat cataaaaaga ttaaaagaaa tataaaaaag
     9421 agaatattta aggattgtta aaatttaatc ttagaaaaaa ataactggaa caagagctat
     9481 ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg aaagaagtcg
     9541 ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta agtccattta
     9601 ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca aaactgaaaa
     9661 aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat ggtcaaaatg
     9721 ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca atgacgatca
     9781 atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg atccaattag
     9841 gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca cctatgctga
     9901 aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg gtcaacgacg
     9961 gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat gttgcaacac
    10021 aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag ttgaaagcag
    10081 cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag atttctgatg
    10141 aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa aaactgggca
    10201 cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct tccccgttga
    10261 atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat aataatctgc
    10321 cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt atcatgggaa
    10381 tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat ttatcaacaa
    10441 tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt agccaagaac
    10501 tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta ggccatccaa
    10561 ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt cgtgaacaga
    10621 agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca gtcttgttag
    10681 aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat cagcttacgc
    10741 catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa actgcgttga
    10801 tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa aaccaagtga
    10861 gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc aagaaaaaat
    10921 ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat ggtgcaaaaa
    10981 tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa atcgttctat
    11041 caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa gaagagctga
    11101 ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt gttcaagata
    11161 tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat tttttagtgg
    11221 atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt gtggcaaaca
    11281 agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt aattttgcta
    11341 cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg agaaacaaag
    11401 aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg aagcttgacc
    11461 cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct gtagtggcag
    11521 ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg gcaagaaatg
    11581 gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt ggaaaactaa
    11641 cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca aaagcaaaag
    11701 catctttagc tatgttagat attgattcag ccaaggaact agcacaagta attgctgcag
    11761 tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga atccaaaaag
    11821 gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt ggtgaggaaa
    11881 tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag acagctatac
    11941 aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga ataaagcaag
    12001 atttacagtt attttattta ctgcagatct tgcttttttc tctatcagaa aatatgttta
    12061 ttattagaat tttttatagt taaggttagg catcttaaga aatcaggcaa ctccaagata
    12121 tcttcaggta gaagagaagt cgcctaacat tgtaggatca taggtgattt gttggacagg
    12181 tcaagctgat atttgagcct gatgttagaa ggaatttctt tttacttgct gtagaaatta
    12241 ttatatgact aaaaaggctg ggattttaaa tcccagcctt ttatgacaaa tagaattttt
    12301 atcgatcagt aatcgctgtc gctgcaaatt gttcgatcaa aggaatcaaa gtcaatttga
    12361 ctttgtattt ccgttcgagt gctttttcga taacgaactc attttcagta gtcatagaaa
    12421 tagttgctaa tttacgaggt tcatcagcat ttttttcatt aataactact tcatgttcat
    12481 tttgttctgt gtaaaattta ggatactcag caacggcttt tgaaaaatca gcaaaactta
    12541 aagcggcatt cgtatcagtt gagcgtgtat tttcagttgt gtccgctttt ggtttttccg
    12601 ttttttcttc tggcacactg actgtttctt ctgtaactgg tgtcgcaaca gcttgcgcag
    12661 ttggttcatc gtttttcaat cgttgatcat tccagtaaga cacgatttca ataagaagat
    12721 tgtcacggaa tcgttcgaaa atcccgtttt ctcctgaacg aattctcttt aatacagtat
    12781 tgaagttgtc atcgattggc acgttgatcc gtgtatcttc atttgttttc ccagctaatc
    12841 cgatcgttaa gatttgacgg tttttgggat caagcatgac ttgtaacggc aaaccataac
    12901 gtcgcaagct ctcttcttct agagaacgga ataattgtcc tcttacacca tccaatgaag
    12961 gacggaattg atttaataat ttttgtttct gttttttctt catatgttct ctccttcgct
    13021 catacccttt cgattataag aaaaaaacag ccaaatgaaa aggagtaatg caaaaaaact
    13081 tgcgtatacg caaattacaa cagaaaaatt tgcgtatttt cccgtttttt gaaagaaaaa
    13141 taaaaaatgg aacggattat gtatatatac ataatccgtt ccattctttc tattttttcg
    13201 gtatcaaggc aaaaacaggt agttcaggtg aataaatgac ttcatgttcg tgccagggtt
    13261 tgaccattag cgaatgatcg aaccgttttt tcagttcttc gatgatttga tcatgtgtcc
    13321 agtttcttgc aggaaaatgt tggattttct ctgcatcgat caaaaagaca aaatcggaat
    13381 gaaaagtctg ggtaacttct tccgagagag aattcaagcg ttcgattgga tccataaaat
    13441 cacctttcga cttaaaattg ggtagtatct gggtcttttg ctttgccgac tacaccatct
    13501 aactgatcga tttgtttcat ttcttcttct gttaattcaa aatcaaataa ttcagtattt
    13561 tctttgattc tgcttggtgt cactgactta ggaagaggaa ggaattcgtg ttgcagcgac
    13621 caacgcaaag caacttgtgc aatcgtcttg tcatgtgctt cagcgatttg tttcatttca
    13681 ggcacatcga agattttacc agtgcctaat ggactatatg cttcgaggat catatcatgt
    13741 ttttttgcat actcaactac agttgtctgt aattcgcctg gtgcaaggaa aacttgattg
    13801 accatcggca taatttttgc tgtttttgct agtgtatcta gatggtgggg taagaaattg
    13861 ctcacaccga ttgctttgat tttacctgct tcatacagtt cttcaaatgc tcgccatgta
    13921 tctgcatttg cttgttccca attatcacga aaagcaacag ggtttggcca gtggatcaaa
    13981 aacagatcta aataatctgt ttggagcttc ttcaatgatt cttcaaaaga agacatcaca
    14041 agttcatagc tgtggtttgc attccataat tttgttgtca agaatatctc ttctctagga
    14101 attccacttt ccttaatcgc ttggccgacg ctttcttcat tcttgtatcc ttgggcagta
    14161 tcgatatggc gataacctgc agccagcgct tctttaacag aggaaacagc gacatcccca
    14221 tcaggtgttt gccatgtgcc gaatcctact accgggattt cgtaaccatt tgatagacga
    14281 taagtgcttg ttaatgaatt catactttca gctccttttt tattcgttca actataagtg
    14341 tagcgcattt ttcgaaaaaa agaatccatt ttgtttctac tcttgaaatt tttgtttaaa
    14401 agaaaatgat tttgattctg gtatttttga ttttttttcc gtaaactaag acagaaggga
    14461 atgagaaaat ggatatctat ttaaaaaaag caattctgca tattattgac agagaaactg
    14521 gttctccagt cttttcacaa aaagagctgg atctgacaaa agaatatatt cgtgattttc
    14581 ttcaaaagaa gatccaaaaa atctcttctg ctcaaacaaa aactggacaa ctagcagaag
    14641 aaagcatgat cgttgaatca cttaaaatcg ctcaagaaaa ttttgtggaa gcaagtgaag
    14701 caatcgttca gcggtggttc gatatctacc aagaaagtga agaagcacct agtgcagatg
    14761 tatttgttgt cttgtatgaa ttagatacag tgatgtactt atctttattg aaagtcaatt
    14821 atcgtgaggc ttacactcac tttgttgaag cagacgaagc agggatcgac aaccgcttga
    14881 ttttgaatcg agcaattcta ggggcgaaaa cacaaaaagc agatgaagca ttcgctgtga
    14941 atttgactga ttggacctac gaattaattg aaaaaaaata tgagttttct ggcaaaaaag
    15001 agctttattt ttctggaaga gtgatcgaaa gtgttcctgc accttcttta gaagaaaatg
    15061 taaaagtgat ccaaaaagta gccaagcatc ttggaaaaaa atttgagaca gaagaatttg
    15121 atatcatggc tgatttgaaa gaagctgtct atgatacgat agaagaaaaa ggtcggttgg
    15181 atcatgagat gattgcggaa aaagtcttca aggaaaacat cacggcaaaa atggctttta
    15241 aagaagaagt acaagagcaa ggatttgtcc cagaagcacc tcctgtaaaa gaagtacaag
    15301 aaatttctga gaaaaaattt ggaaaacaaa aattcaagct atcaaacggg atcgaactga
    15361 tcgtaccagt agatgtatat cgcaacccag atttgattga atttgtgaat aatccggatg
    15421 gtacgatatc cgtgatgatc aaaaatgtgg atgaagtatt gaatcgttta taaaaatgac
    15481 tagaatatta ggtgttcaag taccagtgat cagttaaatg aattgtgtca agagaaggat
    15541 cggaaaagac gaatataaca aaaaaagagc gtgagacaaa agtaaagaac acttttgtct
    15601 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcttat ttcttggagt
    15661 taaacgcttc tgtcccagcc tctttttatc taataaaatt ttaagaccat ttactaatta
    15721 tcgatttttt ctgccgcatt tttaggcact tcagaagcct ttatttcttc ccagcttaat
    15781 acacctttac gaggattgac tttgagttta agatacgcat tcatctttaa tggatgttct
    15841 ctttcttcgc gaagcgtcac ctgttttttt tcaccatctt tattataagc cgcttgcttg
    15901 taggtataag tcgtgaattt ctctccgtta tctgcttggg tagctgacat ttcgccattc
    15961 gtcgtgattt ttgtataata agcttcgccg ccgtaaaaat aatgataagc tgcaaaactt
    16021 ccgccgagaa atatgcctaa aacgacaagt acgccaatta attttttcat gtacttcacc
    16081 tctttcctta ttattaacga aatagaagat ttcgtctatt gaaagttgtt ggcaacagct
    16141 gaattttaaa cttttcctca ttttgttctt attgcttcaa aagaaagtta aggactatct
    16201 tgaagttttt ctcaaaaaac acattttttt atttataaaa ggtacttttt tcgcgtataa
    16261 gacagacgag tgctcttagt tgactttgac caatattgac gtataataag cttagttcga
    16321 atcttacaaa aagtaagtcg gacgtattct ttttgattta gtcaaaaaaa gactataata
    16381 aaaaggtgag agctgaaatt tttcagtgat ctatattatt taggaggttt gtaaattatg
    16441 gcaaaagaac attatgacag aagtaaacca cacgttaaca ttggtacgat tggacacgtt
    16501 gaccatggga aaactacttt aactgctgcg atcactacag tattaggcaa aaaaggccta
    16561 gcaaatcctc aagactatgc tagtattgat gcagctccag aagaacgtga acgtgggatt
    16621 acgatcaata ccgcacacgt agaatatgaa acagaaaaac gccactacgc gcatattgat
    16681 gcaccaggac acgcggacta tgtgaaaaac atgattacag gggcagcaca aatggatggt
    16741 gcaatcttag ttgtttctgc aactgacggt ccgatgcctc aaacacgtga acacatttta
    16801 ttgtcacgcc aagttggtgt aaaatacctg attgttttct tgaacaaagt tgatttagtc
    16861 gatgatgaag aattgatcga tttggtagaa atggaagttc gcgagttatt gagcgaatat
    16921 ggtttcccag gcgatgacac tcctgtgatc aaaggttccg cattaaaagc attgcaaggc
    16981 gatccagatg ctgaagctgc tattatggaa ttgatggata cagtagatga atatatccca
    17041 acaccagaac gtgatacaga taaaccatta ctattgccag tggaagacgt cttctcaatt
    17101 acaggtcgag gaactgttgc ctcaggtcgt attgatcgtg gtgctgttcg tgtcggtgat
    17161 gaggtagaga tcgtagggat caaacctgaa acacaaaaag cagttgtaac aggtgtagaa
    17221 atgttccgta aaacgttaga ttacggggaa gctggggata acgtaggcgt gttgttacgg
    17281 gggatccaac gtgacgatat cgaacgtgga caagtacttg ctaaaccagg ttccattact
    17341 ccacatacaa aattcaaagc agaagtgtac gtgttgacaa aagaagaagg tggacgtcat
    17401 actccattct tcaacaacta tcgtccacag ttctacttcc gcacaactga tgttacagga
    17461 acaatcacat tgccagaaga tacagaaatg gtcatgcctg gtgacaacgt gacgattgat
    17521 gttgacttga tccatccaat cgctgttgaa aacggaacga cattctcaat tcgtgaaggc
    17581 ggacggacag taggttcagg tatcgttaca gagatcgaag cataagaaac gcgactcgaa
    17641 tattttggta atgaaaaatg tttaaaataa aagagcggtc caaacaggat ttctgtttgg
    17701 accgctcttt gttcttcaat tgtataagaa gagattgtag aagcatgaac tttcgtttta
    17761 cttcagtctc ttttattcat catgagagtg ttcatctatc ggtatgcagt ttttaatact
    17821 ttcttcgtat ccattttttc aaaccactta ttctaccttg tgtctgctca actggcgcat
    17881 tatcaataat cagcaaagca atcataacat atgcaatcca actatctcta gaatatagag
    17941 tataacgtga gacccagttt gtagcgtact tgcttttata ttctcttaat ccatggaaag
    18001 aataaaaatg agaaccaaac tcgtaaacca agtatgcaat cctttcctgt aaaaaactct
    18061 ttctggaagt tccgacattt gaaagagggg ccatccctaa attgaaccat tggatatgtt
    18121 cttctttcat ataggcaaac aaatgcaaga acaagaaatc catactgcca gaaggtgctt
    18181 ttttagaatc atatcgcatc agatcaatcg ttcctacttt attgttcgtg taagtaggca
    18241 tgatcgttgc aaaagcgaca atttcttctt gggtattttt gacaactgca ataggcgctc
    18301 tttgtagata atcttcagag aaaaagccta aagaaaaccc tttttccttt cgtgaaccca
    18361 accaattatc agagatattt ttgaaagtac tcatttgctc agtagaaaat ggtggttgta
    18421 agacatcaaa tgtaaatcct tctcgttcga tccgattcaa gacagcacga gtgcccttca
    18481 tttttttccc tgaagttgta aaactattca ggtctacata agcttcttcc cccatcttaa
    18541 tgaaatcgta gccgaattca tgcaaaatca taacaatctc ttcgcttgtt tcgtagaaaa
    18601 ctggtaaata gcatagtcga tctgtttctt cgataaaagc ttcgattgct tctggaaaat
    18661 cttctttctt accagaagga tcacccatta caatacattt attattgaag caagcgaatt
    18721 ggagaagaac agttggttca ccgtcttttt cataggcaaa catccgctta tcttttaaga
    18781 agatcaattg actatcggag tttcctccat aagttgtaag gatcttcagg gccttttctt
    18841 cattaaaggc ttcgccaatc tgtttctttt ctccttgaag gaaatgaaca aatagaacga
    18901 tcatgaaact aacagcgatg atggccaaca atcccgaaaa ccaaatcttt tcagaaggaa
    18961 ataagaaaaa ggaaataaaa tggtgacgcc gatgagggaa atccggcaga ttgtataccc
    19021 caataacgat gtaaagcaag gacagtgcac caataatgat tccatcgatc gtacgccact
    19081 cccatgaata gatcaattgt tcccgaaata attcgttttt agaagcaaga atgatcagaa
    19141 gcagaataga caagaaaacc accggtgtga aactaaaatc acttaataaa acataaagta
    19201 aagctagaac aatcaagaag attgtaggca aatatgctcg tttcacacgt gctgcgatcc
    19261 ctctgcccat aatgattaaa agaaatccca atagtatact aggaaattgg ataataaaat
    19321 gaaatttcaa tgggttcaaa ctatgaagcc agcgaaactc tgtaaaagct tgcgggatag
    19381 tggcagaaag tactagcatg attccagaaa agtataataa gacaaccacg attttatgcg
    19441 caatttctgt tgctaattgt ttagggatac cagaataacg ctgatcaaaa gtggaaccga
    19501 tatttttgaa gaaaaagacg attccaatca aaaacggaat gatgtagtag aacaggcgat
    19561 agagcaagat ccacacaacg actatttctc ttggcacacc aatagcggac aacccgataa
    19621 tcatcattac atcgaaactc ccaatttctc ctggaatcat agacacgatt cctatcactg
    19681 aagcagcaat gaataatgga attgtttgcc acagatcaat ccggatttcc attaaataac
    19741 caacagaaag gaaactaaac aggacaccgg tccattccaa caatgaaact agcaatagct
    19801 gtccttgagt tttaagtgag gtaccaccaa ggaatccttt ctttttgaaa gtagtaaata
    19861 aaaagacgac aggaaaatat agaccgccgc cgatcaacca tatccaatat tgcttcaaaa
    19921 aaggagcaac tggcgtgaag actacaagta aaaaagaaag cagactgtaa atagaaagtc
    19981 cagccatcaa aaacaagaaa actttcgata atgcttggat cacgtttctg ctctctttct
    20041 tttgtccata tagttcagag cgaagcccca cactaacaaa cccgccgaaa ccggcaatat
    20101 tgttgatcgt attgatcagc cagcttgtct caaacaggta acgaggattc tgcttttgtt
    20161 caagcatccg attcaaaata atatcataac caaccatagg taacacagag ataagaccaa
    20221 tcaatagcat tagtccgctt ttccatacag gtatagtggc aaacgtttct cctaattgct
    20281 ggatagatag agttttaccg atggacatca attcaccgac aataatgaca atgacagaaa
    20341 tcaaaaagat tgttttgaac agtcctaggt ggtttttcag ccattgtatg gtatttttta
    20401 acaaataaat caccttctat tcctaatagt tatgtttcag aaagaaattg aagaacttct
    20461 cgattgaagc gttcaggatc ttttctagct aattcatgtc cttgttcttt cacaagcaca
    20521 aaggaagctt ttggtatagt tttagctata tacaaagaat gttttagctt gattacatct
    20581 ttttttccca cgatgatcaa agtgggggag ttgatttttt ttaaatcatt ttctgtaagc
    20641 ccgatgtcat gcagcaaaag tttgataact aaaagatttt tgcgaagact tgggcgaaat
    20701 aaagagagta accataccca tgcataatga atattactga tgactctggc agaaaaacga
    20761 acgcctttaa caagcgtgtt tccagaattt aaaatcaatc gatgaacttt tttagggaag
    20821 ctgctggcaa ataccagtgc tagatttgct ccatcactaa atccaagaaa atctgcctga
    20881 tcgatttttt ccagcaacat gatcgtattc agatcctcgg ccattaactg aaaattcaac
    20941 atagatgctt cgtttgtcga acgaccatgt cctcggctat ctactagata cacggtatag
    21001 tagcgttcga gtacagggac ctgttctgaa aaaaagcggc cgctgccgtc attgccatgc
    21061 agtaaaaaga gagggaagcc ttgaccgctc ttttcatagt aaatttcgct cccatctggc
    21121 atttttgcat atttcttttc ttttttcaca taatcaccta ctgtgtaaag tataacgatt
    21181 atatcagtca ttgggcaatt gtttttactg aaaaacaacg atcattttcg taagatgtca
    21241 aaaaatacag gaaaattcat tttttcttaa ggcgtacaca gaaatcaagg aagaaatagc
    21301 caagaagata aagaaatagt aagataaaaa aagatgtcaa aataactagg tgatgaaatg
    21361 aagcgaaaac gattatctat tatccgtatt cttttttaca tgatcattct gacggttatt
    21421 ggtgcggtgt tgtttttatg aggaagaact tatcgttcgg taaaacgagt ggaaagctat
    21481 caaatagaaa taacaacagc tgcaaaaaat tatcatatgg aaaactacga gaatttgatc
    21541 aaggcgataa tattgaccga atcaaaagga aaagggacag atctcatgca gagctcggaa
    21601 agtctgcatg gagaagctga gatcattgat aatccagctg acagtattga tcaaggtgtc
    21661 aaatatttgg cggaaatgat agtagaagca aagaaacaag gatgcgattt atggacagct
    21721 gtccaagcat ataattttgg gaaagattat attgcctatg taaaaaatca tggcggagaa
    21781 aacacagtag aattagcaga agcgtattct aaagatgtgc tgagcccact tttaggaaat
    21841 gaggaaggga aacaataccg atattggcgg atccagtcct tgctttacaa tggcggctat
    21901 ctctatcata atggaggtaa catgttttat cctgatattg tcaaaatgaa tgaaaaaata
    21961 atagagacct atgaaaaagt ctttaagtaa aatagcagga aatgttcaat catgaataaa
    22021 attaaatgaa agaaggagtg cgcaaatagt ggaaaaaagg caaaaaatgg aaaatcaaga
    22081 agtggggtac acaaccaaag actggatgtt acggtttgtg aagggaatgt ttatcggttc
    22141 aggatttatc ttgccaggag tcagcggtgg tgcattagca gctgtctttg gcatgtatga
    22201 gcggctgatt tcttttttag cccaccttac aaaaaatttc aaagaaaatg ttttgttttt
    22261 tctgcctgtt ggtctaggcg gagtgacagg catctttcta ctttcttttt tagtcagttt
    22321 tttattaggt gcgtatgaaa caacgatatt atggtttttt gtcggatgta tcgctggaac
    22381 tgttcctgcg ttatggaaag aagcagggaa aaaaggaaga gatacttctg atgtgatcat
    22441 catggttgtt acttttgttc tggcttattt gtttttatta tacggcgctc aattatttga
    22501 cgggcaagtc gatcagaatt ttggaacatg gctgattgcc ggcggattga ttggtttggg
    22561 tatgatcgtc ccaggattga gcccttctaa ttttttggtg tatatgggat tgtataaagc
    22621 gatggctgac ggatttaaag aagtacgact tgaagtgatt gtgccgatcg gaattggtgg
    22681 gattctttgt gttcttggat tgtcaaaaat catggattac attttctcaa aggcatatag
    22741 caagctattc catttcattt taggtgtagt ttttgcttca acgattatga tcattcctac
    22801 cgattacgcg ggattgggag ttgctggggt actagcttgt cctgttcttt ttatagccgg
    22861 tacagcacta ggttggtgga tgagccgttt ggaggaacaa tataagtaaa gatagattga
    22921 taataaaaac agcacacggg tgattcaaac aaaaaggttg gcatcttttt tgtaaaatca
    22981 ttcgtgtgtt tttctataaa ttttataaaa acaagttgtt tttaatcttg gaacacgcta
    23041 gacttaaaca cgtgattatt tttgaaagtt ggcggaaaat ggagaaaaag aaaatgaatg
    23101 gacttacaca gcaagaggta gttcagaaaa tggcttctgg ccagcaaaat gactaccagg
    23161 aagatgcatc aaaaagtaca aaacaaatat tcagcgataa tatattgacg ttattcaatt
    23221 ttctgaactt tggtattggg atttgtctgt tatttgtagg tgcgtattcc aacatggcgt
    23281 atttagcaat tattgtcgtc aatatcgtta ttggaattta tcaagaaata catgcaagaa
    23341 atcttgtacg gaaattatcg attgtttccc aatcagaagt actagtgatc cgggacggta
    23401 aagaacaatc gatttctact aaagagctgg tattaggaga tttggtaaaa atcggagcag
    23461 gagaacagat accagccgat ttacaggtta tatctggacg ggcagaagca aatgaagctc
    23521 ttttgacagg cgaatctgat ttgattgtca aagaaactgg agctgaattg ctttctggaa
    23581 gctttttgac aagcggttct gtcatggctg aagttatccg agtaggtgca gataattatg
    23641 ctgtccgctt gactagcgag gcaaagactc acaaagctat tcgttctgaa cttgtagatt
    23701 cgattcgcaa agtatccaaa ttcactagtt tcgtgattat tcctttgggg atcatactat
    23761 ttttggaagc actgttcatc cgcgatgctt ctatcaaaat ttctgttatt gcatctgcag
    23821 cagctttgtt aggcatgctt ccaaagggtt tggtattgct aataagtatt gcattaacga
    23881 caggggtaac caaactggca aaaaaacgaa tccttgttca agacatgtat tcaattgaaa
    23941 cgctggccca tgtcgataca ttatgcttgg ataaaacagg gaccattact gaagggaaaa
    24001 tgagtatcca gcgggtagaa gcactacatc cgctgtacga gaaagccatc ccagaaatta
    24061 tggggacgta tctggcagaa agcagtgata acaacatcac tatgcgggct atgagagatt
    24121 attttgagct ttctaatcgg tatgatgtga caaacaaagt cgcattttct tctgatcaca
    24181 aatggggcgc gatggaattt ccagaactgg gagtcgtgta cgtaggagcg cctgaacgtt
    24241 tggtggaaga agatcggctt ccggacagtc taaaaacagc ccaagcgaat ggctatcgcg
    24301 tacttatgtt ggggatcgct ccaaatcagc aattgaacga agaaaaacca gcatttgttg
    24361 agccggttgc tctgtttgaa atcgatgatc caatccgaaa aaacgctcaa gaaacactag
    24421 cttatcttca tgaggaaggt gtggatctga aagtgatttc tggagacaat ccttttactg
    24481 tctccaatat cgctagacgt gcaggattac cgaattatga tgcgtatgtc gatctttctc
    24541 aaattactga agaaatggaa gtgcgagaag ctgctcatcg ctatacggtt tttggacgag
    24601 tgagtccgca gcaaaagaaa ttgctggtaa atgaattgaa agaaagcggc agaacggttg
    24661 caatgacagg cgacggtgtg aatgatgttt tggcgttaag agaagcagat tgcagcattg
    24721 ctatggcaga aggtgatgga gcaacacgtc agattgcgaa tctggtattg ttggactctg
    24781 attttactac attgccagaa gtcctgtttg aaggacgccg agtggtcaac aatgtgacga
    24841 aagtctcagg catctttttt atcaaaacga tttattcatt tattttatcg attatatgtg
    24901 ccgttacagc aattggattt ccgtttatcc ctatccaaat cacgctgatt gatttagcga
    24961 ttgaagggta tccttccttc tttttatctt ttgaacaaga taaaagaaaa atcacttacc
    25021 gttatttgcc tacagcactt attaatgctt taccaaatgc cttgcttgta gtagtgaata
    25081 tcattgcggt gtatctactt ggaaaaacat tcgcatgggg aaatgctgaa actactactt
    25141 tgatgtatta cttgctgatt gggatcagtt gcatggcagt tgtaaaagct tgttatccct
    25201 tcaacccatt gcgcatcttc ctagcagtaa cgacgatcgt agggatatat gtagctgcaa
    25261 tgctgttcca tggaattttg gaagtaaact tagggttggg agagagcgta ggatacttct
    25321 ttgtattcat gctcgtaaat attgttcttc gagtattgta ctggaaggct gatattcaaa
    25381 atcagttact gaaaagagta gcaaattgat gcttaatgag atagaaatgt gttatacttg
    25441 aaaaagcaat gaaatatgat acaatcaaac atgtataatt gtgtccttta aaatcgcact
    25501 gatttcagtt agtgcgattt tttaccggtt attctcctga aatatcttct gttaaaccca
    25561 aaagatatca atagagcagg gggtgaaaaa atggctcaac ggattcctca agaggttatc
    25621 gaaacagtac gcagtcaaac gaatatcgtt gaggtgattg gacaatatgt ccagttgaaa
    25681 aagtctggta aaaattactt ggggctgtgt ccttttcatg aagaacgtac accgtctttt
    25741 tctgttgcag aagacaagca gatttttcat tgctttggtt gtggtaaagg cggaaacgtg
    25801 tttacttttc ttcaagaact agaaggtcta agttttccag aagcagtggt aaaagtggca
    25861 gacttcgaac agataccgtt agaagatcaa tggcgtcagc gtactatagc tgtccaaaat
    25921 cctgaatctg ctacggggaa actgattgct gctcatgaaa aagcagcgga aatctatcat
    25981 cacatgctat tgcatacaaa agctggacag ccagctttag aatatttgca aagtcgtggg
    26041 ttgtctttag aattaattga agaattcaac ataggttttg cacctaatga gcgttctttt
    26101 cttcagcaag tattcaagaa tgaatcaatt tcaaatgaat tgttagaacg ctctggattg
    26161 tttgtcacgc atgatgatgg ccgtatgtct gatcgttttt atcaaagagt gatgtttcca
    26221 cttcgtaatt ctcaaggcca gacgatcggt ttttcaggac gctggcttgc acctgaaaaa
    26281 gggcaggaaa aagatcagcc caaatacttg aatagtccag aaacagaact gttcaataaa
    26341 agacaagttt tatttaatct tgataaagca agaagcgata tccggaaaaa cggagaaatt
    26401 ttgttgttcg aagggtttat ggatgtgatt gctgcatggc aggctggtat caaaactgga
    26461 ttagcttcta tggggacaag tctaacagct caacagatcc aacaaatgga aaagctgacg
    26521 aaagaattgg tcttttgcta tgacggagac aacgcaggtt ttgaagcaac caatcgaggg
    26581 attgaattgc ttcggcaaaa cagtcgatta gcactttctg tcgtagtcgt tccagaaaag
    26641 cttgatcctg atgaatatct ccgtaagtat ggagaagcat ctttccaaga attagtggct
    26701 catgggcgcg aaacagtctt tacttttaaa tcacgttatt taaaacaagg gaaaaattta
    26761 gataatgaaa aagacaagat cgaatacctc gaagaattac tagttgaact tagccgagtt
    26821 gtttcaccaa tcgaacaaga tatgtatcta tctcaactgt caacagagtt tcagatcggc
    26881 agagagacga tacaaaaaca actgcgcgat cttcgaagga caaatcagca aaatcgtcaa
    26941 gaacctcagg aaagtcaaca cactcaggtt acgagacaag aaactgcacg gaaaaagaga
    27001 cctttgacgc aagtagaaaa ggcagagcag attctattat atcgtgcatt taaagaagtt
    27061 tctgtccgta atattttaaa agaacgagaa tttcagttta ttcatgatgc atatgcagaa
    27121 gtttattttt tattcgatgc atatgtctca caacattatg aattcaacct tgcagagttt
    27181 ttagactttt tgcaagatga aaatttaagg cggttggtgg tggaaatcga atatttaccg
    27241 gtggcagaag aaagttcgcc acgagaaatc caagacttgc tagatgtgat cagcaaatct
    27301 ggcttagctg atgaaataac attaaaaaaa caaatgcagc aagaagccag acgaactgga
    27361 aacaaacagc ttgagcttga attgacgatt gaaatcatca atttaacgaa acagttaaaa
    27421 caagccaaat agctactcaa ggggggcctt cttttatggc aaatggaaca gataaaaaaa
    27481 cgtatgaagc agcagtagca gctttcatca aagaaaacaa acccaaacga caagttgtat
    27541 atgatgattt atccaatcag cttgctacac cattcacttt gaatgcagat gaaatggaca
    27601 aattgatcca aaagattgaa gacgcaggta tcagtgtggt ggatgaaaat ggtgatccat
    27661 caattcacag cttgaagagt gctgagaaaa aagctgaaca agcaaaaaca gaagatcttt
    27721 ctgcgccaac cggtgtaaaa atcaatgacc cggttcgtat gtatctgaaa gaaattggcc
    27781 gtgtctccct tttaactgcg gaagaagaag tagcgttagc attgaaaatc gaagaaggcg
    27841 accaagaagc gaaacagcgt ctggcagaag caaaccttcg tttagtagta agtatcgcta
    27901 aacgttatgt aggacgaggc atgcagttcc ttgacttgat ccaagaagga aacatgggac
    27961 tgatgaaggc agttgaaaaa tttgactacc gcaaaggatt taagttttca acctatgcta
    28021 catggtggat tcgtcaagcc atcactcgag caatcgctga ccaagcacgt acgatccgta
    28081 ttccagttca tatggttgaa acaattaata aattgatacg tatccaacgt caattgctgc
    28141 aagaccttgg aagagaacct acgccagaag aaatcggtgc ggaaatggat cttccaacag
    28201 aaaaagtccg agaaatcttg aaaatcgcgc aagaacctgt ttcccttgaa acgccaatcg
    28261 gtgaagaaga tgactctcac ttaggtgatt tcatagaaga ccaggaagca acaagtccag
    28321 cagaacacgc agcttatgag ttactaaaag aacaattgga agatgtacta gatacattga
    28381 ctgatcggga agagaatgtc cttcgcttac gttttggttt agatgatggc cggacgagaa
    28441 cattggaaga agtagggaaa gtatttggtg ttactcggga acgtattcgt cagatcgagg
    28501 ctaaagcatt aagaaaattg cgccatcctt ctcgttcaaa acaattaaaa gatttcttag
    28561 aataagcgtg gactattgac cagaagagaa atcagtaaaa ctgtttggtt tattttaaaa
    28621 gaaaaaaagc ttgagactac gcagtctcaa gctttttttt ctataggaag gaaattcatt
    28681 cattattttt aagtaaatcc taaaaataag ctattggcgt gacgtataga atatgataga
    28741 ttaaatggta gcgtaaacct agtaaaggag ccgatcgcta agtgatgaaa aaatgtccaa
    28801 attgcggatc gaaaaaaatg gagcagaata ctatctgtcc agactgcggt catcaaataa
    28861 ctgcagaaga tcagcaaata aaagaatcaa ttgaagaaac aaatacagat gcagctatgc
    28921 aggataaatc aactgaagat gcagtctttc ctgatacaga attaaacgat ccaatcgaat
    28981 ggtcggaatt gaaagattta cctctagaat ctgtaatgga attattcgaa aaagcagaac
    29041 cagaagacga agaaccacct gctcacgatc aagtaactaa tatagagaaa aatgaacaga
    29101 agaaagcaac tgttcatgag acttcggaag aatcaggaaa gaatcaagaa gaaacgcttg
    29161 aatcaaaaca aaaaagaaga gtagctgaac tgaaagaaat cgtcgataat gaggaagaaa
    29221 attcgatact atccgcttat atcaaagcac atcgtgaaga tacaaaagaa gagcacgcga
    29281 aagagctgct caaaatgatc agtgaaaaaa ttgcacagga aaacaaagta gagccagaaa
    29341 aggaacaaga aactgaaaaa gactctgata gagaaaacgc cacaggtaaa gaaacagtaa
    29401 aaataaaaga cgtaaaaacg gatatcacag aaaaaactga agtatttact gaaaaacaat
    29461 tagaaaagga aaaaacgaat aaactgccgg aagcagagaa aaaagaaata ctcgaaaaca
    29521 cagacaaaaa gtcaacagag cccgatgaaa taaatagtga atccgatgct gaaaatcaat
    29581 ctgtaagcaa agagggtact gatcttgaag caaaaataga aaaagaagag aaccagccta
    29641 agctgtttga agcagaagcg aaatcaataa caatcgtgcc agatactgaa aaaacacatc
    29701 aagaatcaaa cttagaaaaa acagatccag ataaagcgca aaagaaaaaa tcaaaaaaag
    29761 taccttatct cgttttagca gcagtacttc tactcggtgg aggaagctgg gcttattatg
    29821 accatcatca aaaagtagaa gccgaagtag cagcagaagc aaaaagacag caacaaatgg
    29881 aagaacttca tgagaaactt gctgcctttt atacagatga tcaccatcaa tttattcgtg
    29941 cagatatgat tcatcaagat ttatcaaaac taaaaaatga tttatccagt cttaagaatg
    30001 aaaaaggata ttcagagtta gaaacaactt accaagatat ccaatctaag atccgagata
    30061 tccaaaaagt gaatgagtgg ttcatagcac ctgccatcgt cgatgatcat ctagcagatg
    30121 acatcaagtt gaaagcagat aaagagatcc aagcaatcga aacggataac acagattttg
    30181 gaaaattgat tcaacaagca caaacagaag ctaaaaatca atatgctgaa ttgcaaacag
    30241 ctaaagaaaa aacagctata gtctttaaag acggaaaagt agtggattca gcaacacgcg
    30301 accaatacaa gacggcaaaa gaagcagtag aaaaagtgaa aaatacagat ctatctgctc
    30361 agttgaatga acaattgaaa caagtagata agatgctcac tgataaagag aaaaaagaag
    30421 aagaggaaaa gaaaaaagca gaagaagcga aaaaagcagc tgaagaacaa gcaaaacaag
    30481 ccgctcaagc agcagctgca gctcaagccg ctcaacaagc tgcggtcgca caagcagcac
    30541 agcaagaagc ggcatcctcg accccttcct cttcaaactc agcgaatcag ccaatcaaat
    30601 ctgccagagc aagtgatatt gccgatgcat ctaatccagc atggacgtgg gcaccaggtg
    30661 tccaaagcaa agtgattgct acatgtatcc aacgtggata tatcgttgaa ggaggttaca
    30721 gattagaaaa agccagaatc gaaaatgggg aaggctatta taatctatat gccacttcaa
    30781 caaaatctgc attgatgaaa ggcattggag aaagtgcttt gccattttac atcgtaacca
    30841 tcaactgtaa aactggatgg ttcggaggaa atgggagcaa ttaattttag gcaaatgaaa
    30901 gaggctgtga gcctgccgtt taacaccgtt tattcgaaaa aggggagtat gacacaactg
    30961 ttgtcatact ccttttttca cctttccaaa ccaaggctca gctattcaag tagataacat
    31021 tatgttatga tagcaaagaa atgtattaag aaaacctttc actatagagg gagaaaaaaa
    31081 tgaacgattt attagcaact atatttacag gtattattat tgatgaaaat gaaaaaaact
    31141 actttgtcca aaaaaacgga caaacctttg gcttaagcaa atcagaaggt gaacacaaaa
    31201 tcggtgaagc agttgaagga ttcggttacc aaaatcaaaa acatgaaaat cggatcacta
    31261 cacaaattcc taaaagccgt atcggtcatt acgcttttgg aatcgttact gctacacgaa
    31321 aagatttagg tgcgtttgtc gatatcggtc ttccagataa agactttgtc gtatctcttg
    31381 atgaattgcc gacaatgaca gagctatggc ctaaaaaagg ggatcgcttg atgatttccc
    31441 ttagagttga tgcaaaagac cgtatttggg gcagtttagc agatgaaaaa atattcaaat
    31501 ctttaagcaa atatggaaca aaagaaatga aaaacaaaga tgtgatagga acagcatacc
    31561 gcttgaaatt aacaggtacg tacgttttaa cggaagattt ctatcttggg tttatccatc
    31621 cttctgaacg atataatgaa cctcgtctag gcgagcagat aaaaggtcga gtgattggtg
    31681 tccgaccaga cggtgtactg aatctttcat tgaagccaag agcatatgaa gctatatcag
    31741 atgatgcaca aatgatttta accattttag aacgttctgc agatcagcaa atcaacttta
    31801 cagataaatc ggatccagaa gaaatcatga aagcttttgg tatcagcaaa ggagcattta
    31861 agcgcgcatt aggtaatctt ttgaaacaag gattgattac acaagaaaac ggtgtgacaa
    31921 aactagtcaa aaaatctaat tgagaatccc ttgcatgttt ttcttaacta gcttataata
    31981 attttaatta acatagtgtt atatcttttt ttatttgtaa ttattataaa ttgttggggt
    32041 tgagtaaatg gtcatgaatg ctatttcggc gatgaaaaaa acaaaacagc agctacatga
    32101 agcggggttt aagctgacac cgcaaagaga agctactctg cttgtgcttt tggaaaatga
    32161 gaaagagcat ttatctgcag aagaaatctt ctttttagtg aaaaaaaaga gtccggaaat
    32221 tggacttgct actgtttatc gaacccttga aatcttgaca gaattgaaaa ttgtcgataa
    32281 agtaagtttt aatgatggat tagcccgtta tgatttgaga aaagaaggcg ccaaacattt
    32341 ccatcatcat ttactatgct tgaactgcgg cacgatcgag gaagtagaag aggatctttt
    32401 acttgaagtg gagcaagtag tagaagaacg ttatcatttt ttagtaaaag atcatcggct
    32461 aacgttccat ggaatctgtc aggaatgcta tgaaaaa
//
LOCUS       DAFEML010000023        32008 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFEML010000023
VERSION     DAFEML010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.023"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            68..1255
                     /locus_tag="LP468_001295"
     CDS             68..1255
                     /locus_tag="LP468_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2080841.1"
                     /translation="MAWWGSQVRHDATVKVIELYEEKNPHVTIDYEFYDYEGYYTKLG
                     TLAASDDIWDIFQLNNQFPQYINQIEPLDEYVEQGIIDISNADESYLATTTYDGQLVG
                     LSNGVNSFAIAYNKNIFEQLNIPEPASNWTWDEFEQISYQITEELGIYAISRFEDFIA
                     GCIIQIPQVEKGLNFYNREDLSNSLGFENPDYLTDFFQLRKNLVDKGAHPEPGGGAAS
                     TTDLSFQAVRDREAAMVFLSSNQLTEILSGAPEDMEIQLINPPRRKADGESGIPLRSS
                     QMLSMAKSSAHKEEAAKFIDFFQNSEEANEILKGERGVPIMSNIREQLARADDATLQA
                     TFDYLEMISDMDNGEVNVFDSALNPEIQDQYNLLVEKVIYEEVTAEEAAESLYEFASN
                     ILG"
     gene            1271..2158
                     /locus_tag="LP468_001296"
     CDS             1271..2158
                     /locus_tag="LP468_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080842.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            2175..3011
                     /locus_tag="LP468_001297"
     CDS             2175..3011
                     /locus_tag="LP468_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2080843.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            3014..3637
                     /locus_tag="LP468_001298"
     CDS             3014..3637
                     /locus_tag="LP468_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080844.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            3634..4926
                     /locus_tag="LP468_001299"
     CDS             3634..4926
                     /locus_tag="LP468_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2080845.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      5285..5382
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5498..6079
                     /locus_tag="LP468_001300"
     CDS             5498..6079
                     /locus_tag="LP468_001300"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL2080846.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            6082..7389
                     /locus_tag="LP468_001301"
     CDS             6082..7389
                     /locus_tag="LP468_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL2080847.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            7805..8293
                     /gene="purE"
                     /locus_tag="LP468_001302"
     CDS             7805..8293
                     /gene="purE"
                     /locus_tag="LP468_001302"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL2080848.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            8286..9410
                     /gene="purK"
                     /locus_tag="LP468_001303"
     CDS             8286..9410
                     /gene="purK"
                     /locus_tag="LP468_001303"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL2080849.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            9423..10718
                     /gene="purB"
                     /locus_tag="LP468_001304"
     CDS             9423..10718
                     /gene="purB"
                     /locus_tag="LP468_001304"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL2080850.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(10898..11275)
                     /locus_tag="LP468_001305"
     CDS             complement(10898..11275)
                     /locus_tag="LP468_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080851.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            11531..12259
                     /locus_tag="LP468_001306"
     CDS             11531..12259
                     /locus_tag="LP468_001306"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL2080852.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            12259..12513
                     /gene="purS"
                     /locus_tag="LP468_001307"
     CDS             12259..12513
                     /gene="purS"
                     /locus_tag="LP468_001307"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL2080853.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            12515..13186
                     /gene="purQ"
                     /locus_tag="LP468_001308"
     CDS             12515..13186
                     /gene="purQ"
                     /locus_tag="LP468_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL2080854.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            13187..15409
                     /gene="purL"
                     /locus_tag="LP468_001309"
     CDS             13187..15409
                     /gene="purL"
                     /locus_tag="LP468_001309"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL2080855.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            15394..16833
                     /locus_tag="LP468_001310"
     CDS             15394..16833
                     /locus_tag="LP468_001310"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL2080856.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            16856..17908
                     /locus_tag="LP468_001311"
     CDS             16856..17908
                     /locus_tag="LP468_001311"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL2080857.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            17905..18483
                     /gene="purN"
                     /locus_tag="LP468_001312"
     CDS             17905..18483
                     /gene="purN"
                     /locus_tag="LP468_001312"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL2080858.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            18480..20015
                     /gene="purH"
                     /locus_tag="LP468_001313"
     CDS             18480..20015
                     /gene="purH"
                     /locus_tag="LP468_001313"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL2080859.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            20031..21305
                     /gene="purD"
                     /locus_tag="LP468_001314"
     CDS             20031..21305
                     /gene="purD"
                     /locus_tag="LP468_001314"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL2080860.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            21427..22341
                     /locus_tag="LP468_001315"
     CDS             21427..22341
                     /locus_tag="LP468_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2080861.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(22474..24039)
                     /locus_tag="LP468_001316"
     CDS             complement(22474..24039)
                     /locus_tag="LP468_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2080862.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(24032..25483)
                     /locus_tag="LP468_001317"
     CDS             complement(24032..25483)
                     /locus_tag="LP468_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2080863.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(25497..26513)
                     /locus_tag="LP468_001318"
     CDS             complement(25497..26513)
                     /locus_tag="LP468_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2080864.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            26733..27821
                     /locus_tag="LP468_001319"
     CDS             26733..27821
                     /locus_tag="LP468_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL2080865.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            27875..29401
                     /locus_tag="LP468_001320"
     CDS             27875..29401
                     /locus_tag="LP468_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL2080866.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            29403..30608
                     /locus_tag="LP468_001321"
     CDS             29403..30608
                     /locus_tag="LP468_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2080867.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            30865..31842
                     /gene="guaC"
                     /locus_tag="LP468_001322"
     CDS             30865..31842
                     /gene="guaC"
                     /locus_tag="LP468_001322"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL2080868.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT        10088 a         5408 c         7261 g         9251 t
ORIGIN      
        1 tttaagtgtt atgttattct tcttgacggc ttgtgggcaa gaagatgaca aaaaaatcac
       61 gctgaacatg gcttggtggg gttcgcaagt ccgacacgat gcaacagtaa aagtaatcga
      121 gctttatgaa gaaaaaaatc cccatgtgac gatcgattat gaattttatg attatgaagg
      181 atattacaca aaattaggta cactagcagc atcagatgat atctgggaca ttttccaact
      241 gaacaatcaa tttcctcaat acatcaatca gattgaacca ttagatgaat atgtggagca
      301 agggataatt gatatttcta atgcagatga atcctattta gcaacgacga cttacgacgg
      361 gcaattagtt ggactgtcta acggggtgaa ttcgtttgcg attgcttaca ataaaaatat
      421 atttgaacaa ttaaatatcc ctgaaccagc ttcaaattgg acatgggatg aatttgaaca
      481 aatcagctat caaatcactg aagaattagg aatctatgct atttcaagat tcgaagattt
      541 tatagctggc tgtattattc aaataccaca agttgagaaa ggattgaatt tttataatcg
      601 ggaagatcta tctaacagct tgggatttga aaatccagac tatctaacag attttttcca
      661 gctgcgtaaa aatctggtag acaaaggggc ccatccagaa ccaggtggtg gagctgcaag
      721 tacgacggat ctgtcttttc aggcggttag ggatagagaa gcggcaatgg tgtttctatc
      781 aagtaaccag ttgacagaaa tattgtcagg ggctcctgaa gatatggaga ttcagttgat
      841 taatccacct cgcagaaaag cagatggaga atctggtatc cctttacgtt cttcgcaaat
      901 gctgagtatg gcaaaaagct cagcccataa agaagaagct gctaagttta ttgatttctt
      961 tcaaaacagt gaagaagcca atgaaatttt aaaaggagaa cgtggtgtac caatcatgtc
     1021 gaatattcga gaacagctcg ctcgtgcaga tgatgcaact ttgcaagcga catttgatta
     1081 tttagaaatg atttccgata tggacaacgg cgaagtgaat gtctttgata gtgctttgaa
     1141 tccggaaatt caagaccaat acaatctttt agttgaaaaa gtcatttatg aagaagtaac
     1201 agcagaagaa gcagcagaga gtctttatga gtttgcgtca aacattctag gatagcagca
     1261 ggaggaaggc atgaaaaaag aaaaactaaa acggttcttg gatcaagaca atgtggtcgg
     1321 ttacgtattt gcttctccat tcatcctagg atttctattg ataacagtga taccgatgat
     1381 cttgtcactt tattattcgt tcaccgatta tcgtttggga aatccagtct catggatcgg
     1441 cttggataat tatataaaga tgctgagtga tgcccgtttt ttgaactcca tccgagtcac
     1501 ttttctctat gtatttgcat ctgtacctgt gaaactgatc tttggtctat tgattgctta
     1561 tcttttaacg aggaatatca aaggaacgac tttctttcgt tctttgtatt atgtgcctag
     1621 tttgatcggt ggcagtattt ctatcgctct agtttggcgg gagttgtttt ctaaaaacgg
     1681 gttagtgaat attttcctgg aacgattagg cgcacctgcg ctttcctggt ttagcgatca
     1741 aaaactggtc atgatccctc ttgttttgat gtctgcttgg caattcggtt cggcaatgat
     1801 catctttgct gcaggtatca aagagatccc aggctcgtat tatgaagcgg cagagatcga
     1861 tggagcgaac aaatggcaga cgttttacaa gatcacgtta cctcttcttt cgccgatcat
     1921 tttgtataac ttggttatgc agacaatcgc ggcgtttatg acttttacgc aggcatttat
     1981 cattacccaa ggtggtccga atgatgccac gaacttttat gctctttatg tgtataacca
     2041 agctttttct tttaattcta tggggtatgc tagtgctatt tcgtggatca tgctgttgat
     2101 tatgggagct gtcacctttc tgattttcaa atcatcaaaa aaatgggtcg ttgtgtgaat
     2161 gagaggagga agaaatgaat aatacagtaa cgaaatggtt tcaatacggt tttattttgc
     2221 tattaggtct agtcatgatt tatccggtct tatggatgat cgcaggttct tttaaaacgg
     2281 atcaagagat tatgagtggt tcgctgaatt tgattccaga gacttttcaa tgggaaaatt
     2341 acgcaaaagg atgggcgggg tttgctggaa tttcattttt tactttcttt aggaattcgt
     2401 ttgtcatctc tgcagtttcg acgataggga cagttctgag ctcgacttgt attgcttacg
     2461 cattatcgag aatcgatttc aaaggaaaaa gattctggtt cgtcgtcatg ttagtaacga
     2521 tgatgattcc tgcacaagtg attttgattc cgcagtttat tatttacaat cggctgaatt
     2581 tggttgggac gtatgtgccg ctgattttac cacatttttt tggacaagca tttttcattt
     2641 accagatcat gcaattcatg gtcagcatcc ccaaagagtt agatgaatca gcgattattg
     2701 acggatgcag caagtatagt gtctttacca aaattatttt tcctttgctg aaaccttcga
     2761 tcatcacgac gatcatcatc cagttttatt ggaaatggga cgacttcatg ggaccattga
     2821 tttatttaaa caagccgaga tcttacacgg tatcgattgc catcaaatta tttgcagacg
     2881 ctggatctag tacgacttac gcgagtatgt ttgcgatgtc tacgttgtcg ctgctaccgg
     2941 tttttctgat tttcttattc ttcaataaat atcttgtcca ggggatcagt acaagcggtc
     3001 tgaagggctg aatatgaaaa agccaataga agagatgttt ctttacaagc tcaactacta
     3061 tgtctgtcgg atttttttaa ccagtcttat cagtaatgct cttttcgctt tagttctagg
     3121 atgtttgttc actttaggat tagtgctgtc tgctcgtgtt gtctatctga tttatttttt
     3181 gatgatgtat ccttcttatt atctatctgt ccattacttg gcagaaaaaa aggtatgttg
     3241 gaggaaagga aaaatcaaac ggatgtgttt catcattacg ttgtttcagc tgtttgtcat
     3301 tatttttgca gttgattggt atttattagt gggaaagatt ggagcttggt atctgattcc
     3361 ttttctattg tgtctgttgc tttttgtatc ccatagtttt tttagtacgc taattgatat
     3421 ctgcaaagaa gataaagcag atagtcttgt ttatttgatc aaaaggaata tctggctgtt
     3481 gtcaaaaaac gtcaaggggt ttctgtggta tttatgcctt ttgtatggac tgttctggtg
     3541 tatacagcat gattttttac tcactgcatt actgtatcca gggctgccat ttgtcacagt
     3601 attttgctta aaagaaaagg agaatgactt taaatgaaga aaaaatatgt acaagtcgga
     3661 cttggtggga gagcgcgttt tttttatgag gcaattgcct ctacgtatca tcaaacttgt
     3721 gaactagtcg gtttttgtga tgtatctcaa acaaggatgg attatgcaaa tcggatactt
     3781 gtgaacaagt atggacagaa aaaagtaaag acatgtatgc catcacaatt tgagcaacta
     3841 ctggatgacg tacggccggc tgaagtcatt attacgtcag tagatcgaac gcatcatgat
     3901 tatatcattc gtgcaatgaa aaaaggatat gatgttattt gcgaaaaacc tctgactatc
     3961 gatgaggaaa aagctcaaga aataataacg gtccaaaaac agacgggaag aagcctgcga
     4021 gtcactttta attatcgtta tgcaccgtat cacacgaaga taaaggaact gatagaaagt
     4081 gatgtgattg gtgatgtgtt ttctatccac ttcgaatggc tgttaaatac gcaacacggg
     4141 gcagattatt tcagaagatg gcatcgaaat aagcacaata gcggcgggct tcttgttcat
     4201 aaatctaccc atcattttga tctagtgaat ttttggttga acagccgtcc ccaaaaggta
     4261 tttgcattcg gtggattaaa cttttatggg atgcataatg cggagaaacg cggagtagaa
     4321 atattttaca gtcgatgcta tggaagcgaa ctagctaaag ctgatccatt tgctatagac
     4381 ctgtcagcca atgaggaatt gcgagaaatg tatttagaag cagaaaaaga cagtggatat
     4441 attcgtgacc gcagtgtatt ttccgatgat atctctattg aagatacact aggcgtaacg
     4501 gtcaaatatg aaactggtgc gattttgacg tattcgctaa acgcgtatat gccgtgggaa
     4561 ggattcaatg tttctttcaa tggcagcaaa ggacggatcg aaatgaaagt gatcgaaaag
     4621 tcttacatca atgcaggtgg agataaaaag gatgaaggag cagccgttct tcagtccatc
     4681 catgtctatc cgatgttcgg tgagccatat gaggtaatcg tcgaacaaga agcgggcgga
     4741 catggcggag gagatccgcg tttattagat gatctatttg gtgaagaaaa agaagaagat
     4801 ccgtggaatc gggcagcaac tcacgtagat ggtattttgt cgattttgac aggaatcgca
     4861 gcaaatcatt ctattgcttc aggaaaagca gtagtgattg acgagcttgt cagcttaaaa
     4921 gaataagaat agatttacgg aaattacttc ccgtagttta taaaatcttg ccttattgcc
     4981 gataggctgt cttttgaaca ctatttattc ggaaaaaggg gctatgacat gctttttgtc
     5041 atgccttctt tttatgtggg ctgctttttt agataggaga aaataaaaat aactatttaa
     5101 acccgaacaa aaaggaataa tgcattaaaa atcattagat tttacaaaaa aataagtaaa
     5161 ccacgttgtc agtttcagaa agtagtgtta gactgttttc aatatttgaa acaacatttt
     5221 ttattcaaat atggcaaact gccttcacgt gcaaaacagt tgcaagaaaa tgaatttaca
     5281 ctattattag ttttacatac ctacttatat atcgtcataa tatggatgac agtttctagc
     5341 cagtaccgta aatgctggac tataagtaaa agattggcta tttcaccctt cttttcttat
     5401 gataaagtgg agggtgtttt tctttaacag aaacatagta ggtttttgca caaaagcggt
     5461 tatttcggta ttaataaatg ataaaggagc aaataaagtg aaagaattag ttgaacgtat
     5521 tcaaaaagac ggacgtatat taggcgaggg cgtattaaaa gtcgacagct tcgtcactca
     5581 ccaagtagac cctgtattga tggaacaaat gggaaaacgg tttgcagaag tatttaaaga
     5641 acaaggaatc acgaaagttg tgaccattga agcttctggg atcgcaccag ctttatttgc
     5701 tgcaagagaa ttagatgttc caatgatctt cgctagaaaa gcaaaaagtt tgacgatgga
     5761 tgaagaatta ttgacagctt ctgtttattc ttttacgaaa caagtgacaa gtacgatttc
     5821 tatttctcgt aaatttttat cttcagaaga caaagtattg attatcgacg atttcttggc
     5881 aaacggacaa gcggcaaaag gattgatcga attatgccag caagctggag cgcaagtaga
     5941 aggaatcggg atcgtcatcg aaaagtcttt ccaagatgga cgtcagttac ttgaagaaat
     6001 gggattgaga gtcgtttctc ttgcgcgtat tgcttccttg acgaatggac aagttgagtt
     6061 tcttgaggag gacgcataat cgtggaaaaa gaaacacaaa atggaaaagc tgcggtttta
     6121 gggctgcagc atctgctagc gatgtatgca ggagcagtag cggtgcctct tttgatcggt
     6181 acaggactag gctttaatca agaacagatg acttatttga tttcaattga tatctttatg
     6241 tgtggattag cgacattatt gcaattgaca gttaaccgat ttttcggaat tggcttgcct
     6301 gtcgttttag gatgtgcgat ccaagcagta gctccactga tcttgatcgg aaccaatgaa
     6361 ggagtaggag ctatctacgg atctattatc gcttctggga tctttgttgt gttagtttct
     6421 ggtgtctttt ctaaaattaa aaaactattc cctcctatag taacaggaac ggttatcacc
     6481 gttattggtt tgactttgat tcctgtagca atcgagaaaa tgggtggagg taatgcaaca
     6541 gcagctgatt ttggtgacaa aacaaatctg ctacttgcat ttgtgacgat tctcctaatt
     6601 gtaggcgtgc aaatgctggc aaaagggttc attcgttcaa tcgcggtatt gattggttta
     6661 gtcggaggaa gcatcttagc tgctttcatg ggaatgattg atctgagcgc gattggagat
     6721 gcgccgttgt tccatgttcc acaacccttt tattttggta aaccaacttt cgacgtatgg
     6781 tcgattttac taatgatcat catttccatg gtcagcatgg tagaatcaac aggtgtatat
     6841 tttgcacttg gtgacattac tgggaaaaat gttggagaag aagaattgaa aaagggatat
     6901 cgtgcagaag gacttgccgt tatcttaggc ggtattttca atacattccc ttatactggc
     6961 ttttctcaaa atgtcggatt ggttcaactt tcgggaatca aaacaagaaa acccatctat
     7021 ttctctgcat tcttcttgat tgttttagga ttattcccta aaatcggtgc gttagcacaa
     7081 atcatccctg agccggtact tggtggagga atgttagtca tgttcgggat ggtggcagtc
     7141 caaggaatcc gtatgctgtt ggaagttgat ttcagcaatg ataaaaatct attgattgtt
     7201 gctgtttctg ttggatttgg gctgggtttc aatgttacgc cgacattatt cagtcaaatg
     7261 ccgcaaacat tgcaaatgtt cactggaaat ggcatcgtaa tgagtagcat tacggctatc
     7321 atattgaatt tgatctttaa tggattgaaa aaagatgaag aaatattgga agaagccttc
     7381 aagaagtaat agagcaaaag aaaggttgtg aaatcagcgt tttgacctga ttgttagaga
     7441 aacaaacgga aaaatagttc ctcgtatttt gccgtttgtt tgagctaata ccgagggtca
     7501 gctgattgaa caccgttgaa ggaagaggtc gtgagcctgc cgttcatctc cgagtcacaa
     7561 ggaacaattt caaaaaaaag cttctcatgt ttgttgaata ttgttccttg tgaccgagga
     7621 gttggcagga gaacaccgtt tatccataaa aaggaatgtt acctaacttt tgtcacattc
     7681 ctttttttta tctttaataa acacgaacaa taaaatgttt ttctttgtta acattcgaaa
     7741 tttctttgac atcaaaaaaa gtgattgtta aaatatgaat gtagaaaaac tgggaggaaa
     7801 aacaatgaca gcaaaaatct ctgtgattat ggggagtact tcagattggg aaacaatgaa
     7861 agaagcatgt caaatattgg atgaattcgg tgtgtcttat gaaaaaaagg tcgtttctgc
     7921 tcatcgaacc ccagatttga tgtttgaata tgcacaaaac gctcgaaaaa aaggaatcaa
     7981 aatcattatt gcaggagcag ggggagccgc gcatctgccg ggtatggtcg catcaaaaac
     8041 aactttgccg gttatcggtg taccggtcca atcacgaaca ttaaatggtt tggattcgct
     8101 tctttcgatt gtccaaatgc ctggaggagt acctgtagct actacagcaa tcggaaaagc
     8161 gggagcaatt aatgctggac tacttgcgat acagatgctt tccatgtatg atttagaatt
     8221 ggaggctaaa ttggctgaaa gacgttcaat gttggctaaa actgttatag aaagtagtga
     8281 tcaacttggt taaacctttg ttgcctggtt caacgatcgg gatcgtcggt ggcggtcaat
     8341 taggtcgtat gatggcgatt agtgcaaaag aaatgggctt taaagtaggt gtgctggatc
     8401 ctgtgagcga ttgtccagcc gcacaagttg cagattggca cattgaaagt gtctatgatg
     8461 acacctttgc gctgaaagag cttgccagaa gaacagatgt cattacctat gaattcgaaa
     8521 acgtcagtgt agaggcgtta aatgcgattt tacccatgtc atttattcct caagggacag
     8581 acttgcttgc gattacgcaa gaccgcctgt tagaaaaatc ttttttggaa acgaataaca
     8641 tcgtgattgc tccttatgca acgatcgtca gtccgacgga tatccaagat gcgattgacg
     8701 ggatcggcta tccttgtgtt ttgaaaacca ctcgaggcgg ctatgatggc aaggggcagt
     8761 atgttttgaa aagtcgggcg gatctagctc ctgccatgga ccttttaaga gaaggaacct
     8821 gtgttttaga agcatggatc ccgtttgaaa aagagatttc gatcatggtg gcaggaaatg
     8881 gtcaaggaga tttcacgact tttccggtcg tggaaaacat ccaccacaac aatattcttc
     8941 atgaaacgat tgctccagcc gcgattgatc aggatgtgat cgaggaggct gagcgtattg
     9001 cccgtgtgat tgcagaagca gtgagccttt caggtgtttt aggggtagaa atgtttttaa
     9061 caaaaacagg cgggctatat gtgaatgaat tagctcctcg tcctcacaat tctggacatt
     9121 attctattga agcttgttct atgagtcagt tcgatgccca tattcgaggt atttgtggtt
     9181 ggccattagg agaaaaagta cgtttgataa gcaatgcagt aatggtcaat gttttgggag
     9241 aacaactgct ggaaagctat cgcttgattg agaataagcc agactggcaa ttccatttct
     9301 atggaaaaaa acaagcaaaa aaaggtcgca agatgggaca tatcactatc ttgacagaag
     9361 acatccagca aacgctggaa gaaatcaaac aaacgaatat ttgggattag aggagaaaaa
     9421 acatgttaga acgttataca cgccctgaaa tggggaatat ctggacggaa gagaacaaat
     9481 accgtgcgtg gctcgaagtc gagattttag cagatgaagc ttgggcagaa cttggtgaaa
     9541 tcccgcaaga agatgtgaaa aaaattcgtg agcatgcatc atttgatatc gatcggatct
     9601 tggaaatcga aaaattaaca cgccatgatg tcgttgcgtt tacacgagcg gtttctgaaa
     9661 cattgggaga agaaagaaaa tgggtccatt atggtctaac aagtacggat gtcgtagata
     9721 ctgcttatgg ctatctcatc aagcaagcaa atgatatttt acgggaagac ttgaaacgtt
     9781 ttacggaaat cattggcgaa aaagcaaaag aacacaaata tacagtgatg atgggtcgga
     9841 cacacggtgt ccatgctgaa ccaactactt ttggattgaa acttgccaca tggtattcag
     9901 aaatgaaacg gaacatcgaa cgatttgaac atgcggcaaa aggagtagaa gcaggaaaaa
     9961 tctcaggagc agtgggaacg ttcgcaaata tcccgccatt tattgaagag tatgtatgta
    10021 aacaattggg gatccgtcca caagaaattt ctactcaagt tctccctcgg gatctacatg
    10081 ctgaatattt ctcagcgatg gcgcttattg ctacaagtat tgaacgtttt gcaacagaga
    10141 tacgcggatt gcaaaaatcc gaaacacgtg aagtagaaga attttttgcg aaaggtcaaa
    10201 aaggttcttc tgctatgccg cacaaaagga atccgatcgg ttcagaaaat atggctggtc
    10261 tagccagagt ggtgcgcgga cacatggtca ctgcctatga aaatgtcaca ttatggcatg
    10321 aaagagatat ttctcattct tcagcagaac gaatcatctt gcctgatacc acgattttat
    10381 tgaattacat gttaaatcgt tttggcaata tcgttaaaaa tctaacggtc tttcctgaaa
    10441 acatgaagcg gaatatgtct gcaacatttg gtttgattta tagccagcgc gttatgctga
    10501 aattgatcga taagggaatg acaagagaag aagcttatga tcttgttcag ccaaaaactg
    10561 cgtacgcttg ggacaaccaa gtgcagttcc gcccgctgtt agaagaagat ccaaccatca
    10621 catcggtatt atctaaagaa gaaatagacg atgcctttga ttatcatcat catttgaaaa
    10681 acgttgacgt gatattcaaa cgagtaggtt tggaataaag aagagtgagt tgcaaaattc
    10741 aattaaaata gaatagcaaa aataaccaaa aaagaagcag atccgttagc ggttctgctt
    10801 cttttagttt attatatttt cttatcaata ataggaacct gattttaaaa gcggctacct
    10861 ctttaccgtg cctctttaca tacaaaaaat agaggaatta agcgtaaatg gcttggctat
    10921 tataactaaa atgctggtta tggagatgtt gcagcaagtt ttcgagaaaa gcgtattcca
    10981 tctcttgtcc attgaataag atctggatac gataatgatt tttgaaacgc ttctgttcat
    11041 gaatctgact gattgaaagt tcgcctttgt gttctgtctg ataaagaaaa gtccttttac
    11101 ggcattcagc acagcgcttg gttgctcggc ggatttttcg gaatgtataa aaactagtat
    11161 ctttattgca taaataaacg tctttgatcg acagcaaatc attatataga caggaacgtt
    11221 cttcagctgt taattctgat aaaaaaagct gaccttgttt tattgcatct tccatcggca
    11281 agtgcctcct cgaacccatt atccaaattt ttagttaatt ctaatatacc atcattaagt
    11341 ataaatgtaa acgcttgttg atggtataag attttcgttt ctgataaaac acgaacatta
    11401 aaagaatcta atgccttaaa tgtacatatt tttgttgatt tataaaaaga tgattgctaa
    11461 aatttaaagt gaaaaaacga acaaaaaacg atgtatttgc ttttaatgta aataaaaagg
    11521 agagacgtac atggagaaga aagaactttt gtatgaagga aaagccaaaa aaatatatct
    11581 tacttctgat gagaacttga tttggataga atatttagat caagcaactg cgttgaatgg
    11641 cgcgaggaaa gaccagataa gtggaaaagg agaattgaat aatcaaatca caagtgcaat
    11701 tttccgttat ctgactcaaa gaggaataaa aaatcatttt attgaacaat tgtctaaaac
    11761 cgaacaatta gcaaaaaaag tacaaattat ccctctggaa gtggttatcc gaaatattgc
    11821 agcaggaagt ttctcaaaac gtctaggtgt tcccgaaggt aaagaattca tcaaaccaat
    11881 cattgaattc tactataagg atgaccagtt ggatgatcca tttatcaatg aagagcatat
    11941 ctatttctta caacttgcaa agccggaaga aatcagtgag ctgaaagccc aagcgttggc
    12001 tattaatgaa attttgaccg aattatttgc taaggtcggt ttggttttag tagatttcaa
    12061 gctagaattt ggccggtcga atggacaaat tttgcttgcg gatgaagtaa caccggatac
    12121 ttgccgatta tgggatgaac gtacgaatga acatatggac aaagacgttt accgcagaga
    12181 tctaggtgat ttgatcccag tctatcaaga agtatataac cgtctatcgg aactaactga
    12241 agaaaaggag cgagtatgat gtatttcgta aaagtatatg taacctataa agattcagtg
    12301 ttagatcctc aaggggaggc agtaaaaaaa gcagtccatc gtatgggata tgaaacaatc
    12361 gaagatatcc gaataggaaa atactttgag atacaacttg ctgatgcaga agaaccaatc
    12421 gatacagtga ttgaaacgat ttgtgacaag ctgcttgcaa atgtaaatat ggaaacatac
    12481 cgatatgaaa tcaaaaaaat ggaggaagta taacatgaaa tttgcggtca tcgtttttcc
    12541 aggttcaaat tgtgacgcag atatgttatg ggcagttcgc gagatcatgg gcgctgatgc
    12601 cgaatttgta cggcatgatg agtcctcttt agaaggattt gatggggttt tactgccggg
    12661 aggattctcc tatggtgact atttgagatg cggtgcgatt gctcggtttt ctacaatcat
    12721 ggaagaagtg attcgttttg ctgaagaagg gaaaccagta ttcggtacat gcaatggatt
    12781 ccagatattg acagaagcag gacttttgcc aggtgtactg agacgaaatg agtctttgca
    12841 ttttatttgc aaaactgtac cattgaaagt caaccccaag acggccttta cttcagagta
    12901 tgaagccgac gaaataatct atcttccagt tgctcatggg gaaggaaatt atttctgtga
    12961 cgaagaaaca cttcaagaac taaaaaaaaa taatcagatt gcctttactt ataatgacaa
    13021 catcaacggc agcgtggaaa acattgcagg gattacgaac aaagcaggga atgtgttagg
    13081 aatgatgcct catccagaac gtgcagtaga agacttgcta ggatcagaag atgggaaacg
    13141 gttctttgct tccattttaa aaaacttcgg aaaggtgacc gtatagatga aaacattgaa
    13201 agaaccgaca gctgaagaga tcaagaaaaa aagaatctat gccgaatggg gattgactga
    13261 tgaagaatat cgaatgatcg aagaagatat cttaggaaga atgcctaatt atacggaaac
    13321 tggactgttt tctgttatgt ggagcgaaca ttgttcctat aaaaattcta aaccggttct
    13381 acgcaaattt cctactagtg gacctcatgt gttgcaaggc cctggagaag gcgcaggcat
    13441 cgtcgacatc ggtgatggac tagcagttgt cttcaaagca gaaagtcaca atcatccttc
    13501 agccgtggag ccttatgaag gagctgcgac aggagttggc ggaatcatca gagatatttt
    13561 cagcatgggg gctcgtccaa ttgcgttgct agattcattg aggttcggcg aattagataa
    13621 tccaagaacg aaatatttac tagaagaagt agttgcaggt atcggcggat acggcaattg
    13681 tatcggcata ccgactgtag gcggcgaaat tgcatttgat ccttgttatg aaggaaaccc
    13741 attagtcaat gcaatgtgcg taggtttgat tgaacacaaa catatccaga aagggcaagc
    13801 cgctggcgtc ggtaattcga tcatgtatgt aggtgcaaaa acaggtcgcg acggtatcca
    13861 cggagcaact tttgcctcag aagaatttaa tcaagaagaa gaacagcaac gttctgctgt
    13921 acaagtaggc gatcctttta tggaaaagct gctgcttgaa gcgtgtttgg aattaatctt
    13981 gcatcattcg gattctctaa taggtataca ggatatggga gcagcaggac ttgtttcatc
    14041 tagtgcggaa atggcttcaa aagctggctc aggacttata ttgacattag atgaagtccc
    14101 acaaagagaa actgggatga caccttatga aatgatgtta tcggaatcac aagaacggat
    14161 gttgatttgt gttaaatcag gagaggaaga aaaaatccaa gaactatttc agaagtatga
    14221 tctagatgca gtcactatcg gtaaagtaac agacgacggg caatatcggc tatatcatca
    14281 aggagaagaa gtagcaaatc tgccagtcga tgcattagct gaagatgcac cagtttatca
    14341 taaagaaatg aaagaaccag ctcgaatcgt agaatttcag cagttagctc cttatcagcc
    14401 agttatcgaa gaacctggac aagtattgct tgatctgctg cagcaaccga cgattgcttc
    14461 aaaacgttca atctacgaaa cttatgattc acaagtacaa accaatacag ttgtccgtcc
    14521 aggaagcgat gctgctgtga tgagggttag agggacgaat aaagcgttag ctatgaccac
    14581 agactgcaac gcgcgctatc tgtatttgga tccaaaaatc ggaggacaaa tagcagtggc
    14641 agaagctgct agaaatatta ttgctagcgg tggtaagccc ttggcgatca ccgactgcct
    14701 gaactatggt tctcctgata aaccagaagt tttttgggaa ttatcgactt cagctgacgg
    14761 aattgctgct gcgtgtgaaa cgttaggaac tcctgttatt tcaggaaatg tctctttata
    14821 taatgaaacg gatggtcaag caatctatcc aacaccaatg attggtatgg tcggattgat
    14881 tgaggatcat aaacatatca ctactcagga attcaaaaaa tcaggggatc taatctatat
    14941 attaggtaag acgtttgcag attttgatgg cagtgaatta caaaagatgc agcttggaag
    15001 aatcgaaggt gtgatccgaa actttgatct atccattgaa aagagaaacc aagagttagt
    15061 attgacagcc atccaaaacg gattgattga aagtgctcat gactgttcag aaggtggctt
    15121 ggcaattgca ctggcagaat cagctttcaa acatcagcta gggatatctg tacagtttga
    15181 attgtcctct gctcaattat ttgcagaaac tcaatcaaga tttgtgttga cagtcgcacc
    15241 ggaaaataag acacgattcg aagaaatgat gggagatgct gctgttttag caggtaaggt
    15301 gacggatgaa gcgataatcg aaatttcagc aactgacggt cagatcaaaa tagaaactgc
    15361 agtagcaaga aagtgctggg aggatgcaat cgtatgtctt atgaagtgaa gagtttaaat
    15421 gaagaatgcg ggatcttcgg tgtttggggt catccagacg ccgctagtgt ggcatacttc
    15481 gggctccata gtcttcagca tcgaggacaa gaaggtgcag gtatcgtgtc caatgatcga
    15541 ggaaagctta aggggcatcg agatttgggg ctgctttctg aggtattcaa agatcaaaga
    15601 aaattgcagc agttaacagg agaagctgca atcggacatg tacgttatgc aacagcaggc
    15661 aatggaagtg tggacaatat tcagcctttt ctattcaaat ttcatgatca gtcgatcggc
    15721 ttagcgcata atggtaactt gatcaatgct cgttccctta gaaaagagtt agaggaaaat
    15781 ggggcgatct tccattctaa ctccgatacg gagatattga tgcatttgat ccgacgaagt
    15841 gaagaaacag attttttaaa taaattaaaa agtgctttga atgaagtcaa aggtggcttt
    15901 gcctatttat taatgacaga aacggcaatg attgccgctt tggacccaaa tggttttcgt
    15961 ccattagcaa tcggacaaat gaaaaacgga gcatacgtga ttgcctcgga aacttgtgca
    16021 ttagaagtta ttggggcacg ttttataaga gatgtccagc ctggtgagat agtgatcatc
    16081 aatgacgaag gaatccagat tgattgcttt acgaaggaca cgcagctttc tatttgttcg
    16141 atggaatata tctattttgc cagaccagat tcaaacatcg cagggatcaa tgtgcatact
    16201 gcacggaaaa atatgggacg gaatttagcg aaagaatcgc cagtaaaagc agatatggtc
    16261 gttggcgtac ctaattcttc tttgtcagcc gcaagcggtt atgcggaagc tagtggaatc
    16321 ccttatgaaa tcggattagt aaaaaatcaa tacattgccc gaacatttat ccagccaacg
    16381 cctgagctaa gagagcaagg tgttcgaatg aaattatctg ctgtacgagg agtagtggaa
    16441 ggtaaaaagg tgattatggt cgatgattca attgttcggg gtacgacaag cagacggatc
    16501 gtccatcttt tgaaagaagc aggggcaaaa gaagtccatg tgaggattgc ttctcctcct
    16561 ttgaaatatc catgttttta cgggattgat attcaaacgc gtaaagaact cattgcggca
    16621 aatcacacga ttgatgaaat caaagaatgt atcggtgcag attctttagg ttttttaagt
    16681 gaagagggtc tgatcgaatc gatcggtctg gaaaaagatg ctccgtattc aggattgtgt
    16741 atggcttatt tcaacggaga ttatccgacg ccgttatatg actatgaaga aaaatatcag
    16801 gaatcactaa aagaaaaagt atcgttcttt taaaagcaga ccaagaaggg agtatatgaa
    16861 ttcaatggca aatgcatacg caaaagctgg cgtagatgtc gaagctggat atgaagtagt
    16921 agaacggatc aagaagcatg tcaaaaaaac ggaacgttta ggtatgatgg gcgctatagg
    16981 aggattcggc ggttgttttg atttatcggt ctttcaatta aaagagccag tccttgtctc
    17041 ggggaccgat ggcgtgggga cgaaattagc agtggcaatc gaagcagaca aacacgatac
    17101 aatcgggatc gactgcgtag cgatgtgtgt caatgatatc ttagcacaag gcgcagagcc
    17161 gttatatttc ttagactact tagcaacggg gaaaaatgat ccgttacgtt tggaaaatgt
    17221 agtaaaaggt gtagcagatg gatgtgttca aggaaatatg gcgctgattg gcggagaaac
    17281 agctgaaatg cctggtatgt actcaggtaa tgattatgat ctagccggat ttgctgtagg
    17341 gatagctgaa aaatctcaat tattgacagg agaaacgatc aacccaggag atgtgttgct
    17401 tggaatagca tctagcggga ttcattcaaa tgggtactct cttgttcgca aaattttctt
    17461 tgagcagcag cagttttctt tatcatcaaa actgccagaa ttgaaaaaaa cacttggcga
    17521 agaattgctt gagccaacga aaatctatgt ttcttccttg cttccgctga tcaaagaaaa
    17581 gaaaataaaa ggagctgcac atatcactgg tggagggttt gtagaaaata tcccgcgaat
    17641 gttaccagaa tctatggctg cacaaatcaa acttggctca tggccgattc ttccaatatt
    17701 cggctgttta caaaaatatg gtgaaattcc tgagatggag atgtatgaaa tcttcaatat
    17761 gggcatcggt atggtcctgg cagtcgaaga atcgaaagta aaagaaatag tacacgaaat
    17821 tgagcaagct ggcgaaaaag tttatgaaat cgggaaagtg atcgccaaag aaaaacatcg
    17881 tgtggtgttt ataggagaag aacgatgaga atcgctgttt ttgcttctgg aaacggaagc
    17941 aactttcaag cgctagccga ttatctatcg aaaaaaggat tggaatcttc gattgactgg
    18001 ttgttttgtg atcagcctga agcatatgtt ttgaaacgtg caactgcgtt gagtgtaccg
    18061 gcagattgtt tttcacctaa agaatttgat tcaaaaaaag agtatgaaga agcaattttg
    18121 cataaattga aagaaaaaaa gatcgatttg atcgtattag ctggatatat gcgaatcatt
    18181 ggaccggtat tgctgaaaaa ttatgataaa agaatcatca atatccatcc gtctctttta
    18241 cctgccttcc ctggtttgca tggcatacgt gatgcctttg aagctggagt aaaagaaacg
    18301 ggtgtcacaa ttcattatat cgaccaaggt gtagatactg gaccaatcat ccggcaggaa
    18361 aaagtgagaa ttgaacagga ggacacgttc gattctttag aagaaaaaat ccatagagta
    18421 gagcatcgaa tctatccaga agtgattagt gaaattattg aaaatggagg ctatctgaaa
    18481 tgacaagagc attgatcagt gtatcagata aaactgggat tgtagcattc gcccaaggtt
    18541 tgattgaaca aggagtagaa atcatttcaa caggaggaac aaagcatgcg ttggataaag
    18601 ctgggatcaa aacgctttcg atcgaagaag tgacagggtt tcctgaaatg atggatggcc
    18661 gtgtcaaaac acttcatcct aaaatccatg gtggtctttt aggaagacgc gatctcccta
    18721 gccatatgga ggcaatggaa acggaaaata tccaaccaat cgactttgtt tgtgtcaatt
    18781 tatatccttt caaagaaacg attatgaaac cagatgtcga aatagcagaa gctattgaaa
    18841 acattgatat cggtggtcct agtatgctcc gtagtgcagc aaaaaaccat gaatttgtca
    18901 cctctgttgt tgatccatct gactatgaag aagtactttc agaattacgt cagtatgggc
    18961 atacttcact ttctttcaga caaaaactag cggcaaaagt ctttcgtcat actgcggcat
    19021 atgatgcact gatcgctcaa tacttaacgg attgggtgga agaaaaagaa ccggaaaaat
    19081 tgacacttac gtatgaacga aaacaaacgc ttcgttacgg tgaaaatagc catcaagccg
    19141 ctgcctttta tcagtccgct cttctggaaa aatattcgat cgcagcagca aaacaactcc
    19201 atgggaaaga actttcttat aataatatcc gagatgcaga tgctgcgcta cggatcatga
    19261 aggaatatga cgagccaacg gtagtcgcct tgaaacacat gaatccttgt ggtattggga
    19321 cagcatctac gattttagaa gcgtgggaag cagcgtatga agcagatcct gtttcaatct
    19381 ttggtgggat catcgttttg aatcgagaag tagatctgcc aacagcagaa cagatgcata
    19441 agctgtttct agaaatcatc attgcccctt cttatacaca agaagctttg gaattactgc
    19501 aaaaaaagaa aaacatccga ttactgacag tagactttgc gcaggaagaa aatcaaaatc
    19561 gagaagaaac ggtctcagtc ttaggtggac ttcttgtaca agatcaagat ctggcaatag
    19621 aaaatgaaga agagtggaaa gtcgtgacaa aacgtaagcc gactccagca gaagcaaaag
    19681 cattagtgtt tgcttggaga gctgtcaaac atgtgaaatc taatgcgatc gtactggcaa
    19741 acgaacgtca gacagtagga atcggagccg ggcagatgaa tcgagtcggt tcagtaaaaa
    19801 ttgcgattga acaagcgcaa gagaaaatgg aaggtgcagt tttagctagc gatgcttatt
    19861 ttccaatgga tgattcggtt gaatatgcag ccaaacatgg tataaaagca atcattcagc
    19921 caggaggaag catcaaagac caagattcta ttgatatggc gaataaatac gatctagcaa
    19981 tggtctttac tgatgttcgg cattttagac attagagagg agtcggataa atgaacattt
    20041 tggtgatcgg tgcaggtggt cgtgaacatg caataagtaa aaaactttta gccagtccga
    20101 aggtggatac ggtgtattgt gcgccaggaa atccggggat gacaaaagat ggtatcaatt
    20161 gtgtcgctat cagtgagcga gatcattcag cgttaatcca ttttgttaag aaagaggcta
    20221 ttgattggag tatcgttggt cctgaagttc ctttgttaaa tgggatcgtc gatgatttta
    20281 tggcggaagg attgaaaatc ttcggtccga caaaagcagc agctctgatc gaaggttcga
    20341 aaagttttgc taaacaatta atggatactt atcaaatccc gacagctaaa tccagaagtt
    20401 ttgaatgtta cgaaaaagca gcagcgtata tcaaagaaaa tggtgcgcca atcgtagtga
    20461 aagcggacgg cttagcagct gggaaaggtg tagtcgtggc taccacagtg aaggaagcgc
    20521 tggatgcggc agaacaaatg ttgaaccagc atcgatttgg ggatagtagc aaaaaaatcg
    20581 tcgtagaaga gtttttggca ggagaagaat tctccctttt ggcgtttgtc cgtaatacca
    20641 aggtgtatcc gatggtcatt tcgcaagatc ataagcgggc atttgataac gataaagggc
    20701 caaatacagg cggaatgggt gcttattcac cagtaccgca aatttcaaaa aagatgattg
    20761 aaaaagctgt ggaagaagtt ttaaaaccag cggctttggg aatgaaagaa ctaggacgct
    20821 ctttcacggg tgttttatat gcgggtttga ttgctacgaa ggaaggacca aaagtgatcg
    20881 aattcaatgc gcgtttcggt gatcctgaaa cgcaagtcgt tctttctcgg ttgaagagtg
    20941 actttgcgca agtaatcgat gatttattag agaatcgtac agtagagtta aagtggcagc
    21001 aagaaggata caatgtaggc gttgtggttg cagctgccgg ttaccccgaa gaatatgaga
    21061 caggaatggt tctaccagat tttctggaag aagagctttc tgtttactat gctggagttt
    21121 cctcaaataa cggcaaacta gttggagcag gaggacgtct ttatttagta gaagcatacg
    21181 gtgagacgat caaagaagca cagaaaaaaa tttacaccgc gttaatggat aaaacgacag
    21241 atggaacatt ttatcgtaca gatattggag aaaaagctgc caatagcgaa ctgatcgtga
    21301 agtaaatcag ctgcttccat ttataaaaaa tacaacaaac ataatcggaa gcgccgattt
    21361 tagtgaagcc ttttcataaa gagtgtggta cacttttgtt gtgtatataa ataaggagga
    21421 gttcagatga aaaaaattca attaggtact tctgatcaga aagcagctgc agtgatctta
    21481 ggctgtatgc gtatcaacaa tgcggaagat ccagtaaaag tgattgagac agcttatgaa
    21541 aacggcattg atttttttga ccatgcagat atttatggaa acggtgaatg tgaagaaatc
    21601 tttgcagatg ctctagcaaa aacatcaatc aaacgagaag atctttttat tcaaacaaaa
    21661 tgtggaatcg ttccaggtgt gatgtttgat ttttctaaaa aacatatcat tgaatctgta
    21721 gaaaaaagtt tgacccgtct gaaaatggat tatgtggatg ctttacttct tcatcgtcca
    21781 gatacattgg tagaaccaga ggaagtagct gaagcgtttg atgaattgga acggtcagga
    21841 aaagttcgtt attttggcgt cagcaatcaa aaaccaatgc aaatcgaatt gctgaaaaaa
    21901 tatgttcgtc aaccattagt agctaatcag ctgcaatttg gcttgaaaca tactggaatg
    21961 atcgatcaag ggattcatgt caatatgaca gatgaagcaa gtatcgatca tgacggtagt
    22021 gtacttgatt attcccgatt gcatgatatg acgatccaag catggtcacc ataccagtat
    22081 ggattttttg aaggtgtatt tatcgggaac gaaaaattcc ctgaattaaa ccaaacatta
    22141 gaagaactag cagctaaata tcaaacgaca ccaactggct tggcttctgc ttggatttta
    22201 cgccatccag ccaatatgca agtgatcgcc ggtacgatga acgtagggcg aatcaaggaa
    22261 atcgctcaag cttcagaaat taatatgtct cgggaagatt ggtacgaatt gtaccgtgct
    22321 gctggaaaca ttttacctta aagattgtca taagcaggtc aaaagggcta taaattaaaa
    22381 agacagaata acttgaaagc tgttttcagc ttcgagatat tctgtctttt tttattgcaa
    22441 atggaaagag tatcattgta cggatttcgt ttattagtta tttttgtttt taaggaaaag
    22501 ctgtgtccga tattcttttg gagaaatccc ttgttttttc ttaaataaat aactgaaata
    22561 gttagggtca ttataaccaa tttcaaaagc aatatctgaa atacgatagt ctgattgctg
    22621 caataatttt tttgctaatt cgattctttg ttctgtcaga taatcgatga atgtttggtt
    22681 aaacgattga gaaaaaatcg tactgaaatg agagggactt aatgcaactt gttgagcgac
    22741 ccaagttaag gacatatctg gatcggtaaa attttctttg ataaaatcca atgcatggtt
    22801 caaaattggc tgatatttgt tccttgaagg ctgtgagggc agagcagtta agaaagaaat
    22861 gaacatataa actgtcgaac ggtaaagcga gtcgtcggcg ctgattgcta agcgttgact
    22921 ggtggatgtg caatgaacca tttcttgcgg gattttcttt tctttcaggc agacatgctg
    22981 gagtagctta gtcaagacaa ataaacgata taatcgtgtt cgagttggtg tgccttgtgg
    23041 tttcgtcaag tgttcgatgt acttagatac ttcgtttttc gataatgaag acaaatcaag
    23101 tgagaggtca aagtaaaaga cagaatcaac tggaagtttc gcttcttgaa tcaaatcctc
    23161 atagctgata atttgttctt taagggaact ggcggtttca agtatcatct gcgtgatctc
    23221 aaaagatgca ggtaattcgc tgattctttc tgcgacagga ccaatggcga cagaaaaatt
    23281 atttttttgt cccttttcta attcatggac caacgtttgg gctacctgat aactggtctc
    23341 gatcacattt tcttcaagag aatcaactat taaaaatttg atgaatcgag aggaaacagc
    23401 agagaagatc acttgttgat tctccctaaa taaaaacttc aaataatcac tgagatgagc
    23461 gtaatcttca aagtctgtac tgacttggtt tgctgctaat aatacggtca tttttttccc
    23521 tgctaaagag cgattgaaag attcagcaag tttcaatgtt tcactgatcg taagtgagcc
    23581 tttgaacaaa ccgttcaaga aatgattttt tttcaattcg aaaacaagat cagaagaagt
    23641 gtgcgtttct ttttgctgca aatctaaagc agttactgct ttttctattg cttgtttcaa
    23701 ttcgctactt ttaatcggtt taagcagata atcatctgcc tgtacctgga ttgctccttt
    23761 catataatcg aaatcgtcga atccactaat aaatatgaga cgagtccaag gaagtagttt
    23821 ccttgcttct tttgaaaaag tcaacccgtc catgaaaggc atttggatat cagtcagaat
    23881 gatgtcgggc tgtaagtcga taattgaaga cagtgccatc tcaccatctc cagcttcgcc
    23941 gacataagtg attggataat aagaaccaag gacagttatt tgttcccgca agttattgcg
    24001 aatgaggtat tcgtcttcga tgataaaaac tttatacatg tttgtttcct ccaattgttt
    24061 tgggagatag agggatcatc agtgtgacag ttgttccttc tcggtatttg ctgtcaatcg
    24121 tgataggttt ttgatcattt ccgtaataaa gaaggagacg cttgtttacg ttgtaaagtc
    24181 cgtagccgat actgaaatct gaatcgatcc ctttggctaa ctctttacgt atttctgcca
    24241 gtttttctgc agggatgcca atcccgttgt ctataacttt gaattggatc atctcatcaa
    24301 ttttgcatgt ggtaatacga ataaatcctt tgtgacggac gtacttcgtt ccatggtata
    24361 cagcattttc aatcaatggc tgcaagatca tttttaaaat agaaacagga aaaagtgttt
    24421 ctggtatatc gatcttatag tcaagcatat ggccgtatct tatttttaag atgactagat
    24481 aatcattgat atggctaatt tctttttcaa gaggaatcca gtcttgtcct ttgcttaaag
    24541 acgtacgaaa aaagccggaa agtgcatggg tcatagtcag agcttcttca aagcagtctt
    24601 gttcgatcaa agaaataatg gcatccaaac tgttataaat aaaatgggga gtaatctgag
    24661 cttgcaatac acgaacttca ctttgtgcta aatggtattg tttcaaagcg ttctcccgta
    24721 aagactggtt tagatcttcc gccattttat tcatgctagc ggtaagtgtt tgtaattcca
    24781 gtgtttccgg cagggttaaa cgaaagccaa ggttccctga agaaagttgt tctgacatct
    24841 cgatcagctg attgatcggt tcttggacct ttctctctaa aaagcgacga ttctttttcg
    24901 catagaaaaa aatggtacta agaactccaa gttccactat tgttaataga atgagcgagc
    24961 ggacaagtgt cgtatttttt ttgcttgcta agtcgatctc cacacgaaca aaatcttgta
    25021 agatatctga cagcagttga gtgacagaat ctacctgatt gatgatctct tcattggtat
    25081 ccataaaatc ttttgccaag atattattga tcagctcgtt ttgataatct tccagtgtat
    25141 cgatcgtacg tagcgataca tctaacgtac taatttcttt aagtgtattt gtattatttt
    25201 tgatctctcg aatatcattc ctaagttctt ctaggatatt ttcctcattg aactcatcta
    25261 cggttacttg gccagaaatc aagtcccaca tactttccaa aactttttga tcaaccttca
    25321 aagcaattgc atctgctttt tggatatttg cgatcgtctg ttgataaatc aaaagctgtt
    25381 gcgaatataa cagtatgctc agtagcaaag ggataacagc aaatagaagc atggctttgt
    25441 ttgcttgggc aaaaatctgt tttatgctta aattttttgt catgatactt ctccagtcaa
    25501 taatttctgg ttgggatgtt agctatattc tgctgggaaa agacagtctc ggaaataaaa
    25561 atatctttag gtaatgtttt tcctgtttga atatttccaa aataacgagt aacggtattg
    25621 gctacatacc agccgacatc aggtttacac tcgactacac aattgacgat tcctgagcgt
    25681 agcttctcga tcatatcttc ttgtccatca atagttacaa tgatcaaatc ttctccaggt
    25741 ttgattgatg tttcttttat cgcagctaaa gcaccgtgag tcatttcatc actatggctg
    25801 tataatacat cgatttcgga taaatcattt gtttctaaat atcgtttcat ctggtctttt
    25861 cctttcatcc gaataaaatc accgacaatt cggtgaacaa tagtcatcgg aggtttatgg
    25921 tcgatggttc catctttttt tagggttggt ttacgattga ttgattccaa aaatccttcg
    25981 gagcgtagct tggtcggtgt ggagttctct gaaccagcaa gttctaggat tctgatttcc
    26041 tgtttctttg aatttgtgaa gtgattgctg acaaataaac ccgcccgatt tccttctgct
    26101 ttgaaactgg ggccaatgtg ggtgacgaaa agctcgggat cattcgtttg aatatgtctg
    26161 tcgacaagta tgacagggat ccctgctcgc tttgcttctt ttaatacaga gtcccacccg
    26221 gattcttgca aaggagtaaa aatgatcata tccactttat aggcaatgaa cgtccgtata
    26281 tcttggattt gccgttcctg attcatgtag ccatttcggt agagaacttg gtaatcttct
    26341 ttttcaagcg cagtgataat tgattcagta tgctttttcc gccagctact ctccgttcct
    26401 gattgcgaaa aaccaacgac tagtgggtca ggtgcttcct ttgtattagg tgtacacccc
    26461 atcatttggt aagcgattac aacaagggct aaaaaaaata aaacacgttt cactttaaat
    26521 cactccatct ggatttgtta gtactatctt atcagataaa agggaaaatc aaagtcaaaa
    26581 ggaatcaatc gaaaaaaatc caagaaactt aaaaaaatcc aagacaaaaa aagtacacct
    26641 aaaaaattta aagtaaatcc cataaaaaaa tcaatgttaa cgctttcttt attagctata
    26701 ctcggtgtat caattgaaat gggggataaa aaatgaaaaa caaatttaga aagattgttg
    26761 ggactatcgc tattttgacc gcaagcattc tattaagtgc gtgtggcaat tcaggatctg
    26821 cagatgatag tacggggtat gtaggaatcg ctatgccgac caaatcagca gaaagatgga
    26881 tcgctgatgg gaacaacatg gtctcggaat tagaaaaact gggttataaa acagatcttc
    26941 aatatggaga agataaagta gaaaatcaag tagcacaaat agaaaatatg attacaaaag
    27001 gggtagatac acttgtgatt gcttctatcg atggttcggc tttaactgat gtgttagcta
    27061 aagcaaaaga agcagatatc aaggtgatcg cctatgatcg tttactgatg aattcagaaa
    27121 atgtcgatta ttacgcgact tttgataatt ttggagtagg tgtatcgcaa gcagcttata
    27181 ttgaagagca cttaggattg aaagaaggaa aaggaccatt cacgattgaa ttatttggtg
    27241 gctcgcctga cgacaacaac gcactaatca attacaacgg agtgatgtct gttttacaac
    27301 catatatgga caacggtcag ttggtcgtgc catctggaca gacgagtttc agtcaaatcg
    27361 ctacgcttcg ctgggatggt tctacggcgc aagcaaggat ggataatctg ttaagcgcaa
    27421 attatactga ccaaacattg gatgctgttt tgtcgccata tgatccaata agtttaggaa
    27481 tcatttcgtc attaaaaggc gtggggtatg ggagtgaaag taaaccttta cctgtgatta
    27541 ctggacaaga tgcgacagtt gctggcgtta aatcgatcat tgccggggaa caaacacaaa
    27601 cgatctttaa agacacacgt atcttagcaa aaaatacgat tgaaatgatc aaagcaatca
    27661 gtgatggaga agaggttccg gtcaatgata ctgaaactta tgataatggg gtgaaaactg
    27721 tccctacgta tttagcaaat acagtatctg tcgataaaga taattatcaa gcagagctga
    27781 tcgacaccga ttattataaa gaatccgatc tgaaaaatta agaggaacca aacaaggaac
    27841 taaagagatc taagtcagag agaggataag aattatggcg gattgtattt taaaaatggc
    27901 agatatcacc aaaaaatttt ctggaatccg agcgttagat tgcgtgaatc tgatgattga
    27961 acgtggggaa atccatgcat tgtgcggaga aaacggagcg ggaaaatcaa cattgatgaa
    28021 tgtcttgagc ggcttgtatc catatggctc ctatgacggg gaaatctttt atgatggaaa
    28081 gctgtgtcaa tttaaagatt tgaaagatag tgaagaaaaa ggcatcgtca tcattcatca
    28141 agaattagca ctaagtcctt atctttcaat aaaagagaat atttttctcg gaaatgaaca
    28201 agcagaaaga ggcgtgattg attgggaact gacagaaaag aaaacatatg aactgctgaa
    28261 taaagtcggt ttgtctatcg acccgaatct tctagtatcc cagattggcg tagggcaaca
    28321 gcaactagtt gaaatagcta aagcattatc aaaatccgtc cgtctgttga ttttggatga
    28381 gcctaccgct gcattgaatg aagaagaaag cgcgaatttg ctgagattga tccgagagtt
    28441 gaaagagcaa ggtgtaacct ccatcattat ttcacataag ctgaatgaaa tcgtggatat
    28501 cgcagatcga atcaccattt tacgggatgg acagacgatt gagacactag aaaatgaaat
    28561 gatcagcgaa gagcatatta ttcgcggaat ggtgggcaga gatttagttg atcgttatcc
    28621 tgaaagaaaa ccggatattg gagaagttta ttttaaagta gaagactgga cggtctatca
    28681 ccctcttgat cacgagcgaa tcataaacga ccacatcaac ttgcatttga aaaaaggaga
    28741 gattgtagga atagctggac tgatgggagc gggcagaact gaattcgcta tgagtctatt
    28801 tggacattct tatggaagca agatatccgg acgtatatta aaggaagggg cagagatatc
    28861 agttaagacc gttccttcag ccattgcaaa cggactcgct tatgtctcgg aggaccgaaa
    28921 atctttagga ctgaatctgc tgatggatat tcgggaaaac gtgacgctga gcagtttgga
    28981 taaaataagt caaaaaggag tattagataa agaaaaagaa gtaactgagg cagaaaattt
    29041 ccggaaaaag atgcgtataa aaacaaactc catccatcaa attgtcagta gtcttagtgg
    29101 tgggaatcaa caaaaagtcg ttttatccaa gtggctgatg acacaacccg atattctttt
    29161 tttggatgag ccaacccgtg ggatagatgt tggggcaaaa tatgagatct acacgattat
    29221 cgaagaaatg gcagcaaatg gcaaagctgt ctgtcttatc tcttctgaac ttcctgaaat
    29281 attagggatg tgtgatcgaa tctatacgat gaacgaagga cgtattacag gagaagtctc
    29341 gcgagaagat gcagatcagg aagtcttgat gaaattaatg acgaaagaag aggtgggtta
    29401 agttggaaca ggcaaaaaat cttacggata aaaaagagaa aaaactaaat ttgaaaagta
    29461 gagcagctga tctttttggt cgctacagca tggtgatcat tttagcggga ctacttattg
    29521 cgtttcaatt gatgacggat ggtattttct ggcgtccatt gaatataact aaccttgttc
    29581 tgcaaaatag ccatatatta gtactagctg cagggatgtt attagttgtg ctcttaggtc
    29641 atgtggattt gtcggtaggg tcagtgatgg cgtttgttgg tgcaattgcg ggcatgatga
    29701 tggtcaatcg ccaaatgaac ccgtggatga cagttatcgc atgtcttgca gtaggcgggc
    29761 tgatcggcgc atggcaaggt ttttgggtag cttatgcagg gataccggcg tttatcgtga
    29821 ctttagcagg attgctgatg tttcgtggac tgacacaagt tgttctagga ggccaatctc
    29881 tagcaccttt tccagctgtt ttccaaaaaa tgtctacggg ttatttacca gacttaagcg
    29941 aaggaagcag ccttcacttc ttgacattga ttttaggaat gatcatcacg atcgtgttag
    30001 ttgttggtca atggcgaaca agaaatcgtc ggaaaaatca tttatttgaa gtggaatctc
    30061 caacagcttt cttggtaaag gcggtattta cagcagtcgt tgtactagga ataacttata
    30121 tctttgcctc ttatcaaggg tatccgatta ttttgatcat tcttggtttg atcgttgcag
    30181 catatgggtt tttgacaaat aaaacagtag caggtcgaca gatttatgcg acgggcggaa
    30241 atcgaaaagc ggctgaacta tcagggatca aaacaaagcg aatcacgttc tgggtattcg
    30301 tcaacatggg agtcatggca gctttagctg gattagtttt agctgctcga ttgaatgcgg
    30361 caacacctca agcaggtaca tcgatggaac tggatgcaat ggcggcagta tattttggtg
    30421 gtgcttcgac ttccggcggc attggaacaa tcatgggtgc gattgtcggt ggcttggtca
    30481 tgggtgtatt gaacaatggc atgtcgattt taggcgtcgg ggtagactgg cagcaggcaa
    30541 tcaaaggatt gatcttgctt ttagccgttg tgctagactt gtataataag aaaaaacgaa
    30601 caacgtagga gaacgccggt tattcagaaa aaagactgtg acaagacatt tgtcacagtc
    30661 tttttttcgc taaaagcgaa cattcattgt ttcgtttgta tagactaaaa ataatatatg
    30721 tttttttacc attcgtataa attctctttt tgctcttgat ttttttgctt aattgagtta
    30781 aattacatag ggcgctaaaa aaagccttga ttaaattaat aatgttcgtg ttttgctgga
    30841 tgtgaacatc aggaggataa tgtaatgaaa gtatttgatt acgaagatat tcaattaatt
    30901 cctaataaat gtatcgtaaa tagccgttct gaatgtgata caacggtcac attaggtaaa
    30961 catacattca aaatgccagt agtgcctgcc aacatgcaga cgattattga tgaaacaatc
    31021 gcagaattct tagcggaaaa tggttatttc tatatcatgc atcggtttga tgaagcagct
    31081 cgaattccgt ttatcaaaaa aatgaaaaag cgtggattga ttacctcgat cagtgttggc
    31141 gtcaagaaag aggaatattc ctttatagag aagttggcag aagaatcgct aaatcctgat
    31201 tatatcacta tcgacatcgc gcatggacat gctaactcag ttattgatat gattcagcat
    31261 attaaaaaat atttgcctga aacttttgtg attgccggta atgttggtac accggaagcc
    31321 gtccgtgaat tggaaaatgc gggcgcagat gcaacaaaag tcgggattgg tccaggaaaa
    31381 gtatgtatta caaaaatcaa gacaggcttt gggactggag gctggcaact ggcagctctt
    31441 agatggtgtg cgaaagcagc tcgcaagccg atcatcgctg acggtgggat cagaacacat
    31501 ggcgatattg caaaatctgt ccgttttggt gcgacaatgg tcatgattgg ttcattgttt
    31561 gccggtcacg aggaatctcc tggcgaaaca aaagtcgaaa atggaatcgt gtataaagaa
    31621 tactttggtt ctgcttcaga attccaaaaa ggcgaaaaac gaaatgttga aggaaagaaa
    31681 atctggatcc aacacaaagg atctttgaaa gatacactag tggaaatgca acaagacctt
    31741 caatcatcta tttcttatgc tggaggaaga gatctggaag ccattcgaaa agttgactat
    31801 gtcatcgtga aaaattcgat ttttaatgga gacacaatct aaaaaataaa taaaatatta
    31861 ggatgttgtg aaaaagttgt cctgcattaa gtaataagaa cagccaaaca aaaatagttc
    31921 tttatatgtt ttgtttggct ggaattatta tcgcagatac aagcttttga acatcattat
    31981 tcagaataag ggactgtgat aagatttt
//
LOCUS       DAFEML010000024        31478 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFEML010000024
VERSION     DAFEML010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.024"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            271..1140
                     /locus_tag="LP468_001323"
     CDS             271..1140
                     /locus_tag="LP468_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBL2080869.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1349..2374
                     /locus_tag="LP468_001324"
     CDS             1349..2374
                     /locus_tag="LP468_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2080870.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2413..3363
                     /gene="manA"
                     /locus_tag="LP468_001325"
     CDS             2413..3363
                     /gene="manA"
                     /locus_tag="LP468_001325"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL2080871.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3457..5160
                     /locus_tag="LP468_001326"
     CDS             3457..5160
                     /locus_tag="LP468_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2080872.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5162..7195
                     /locus_tag="LP468_001327"
     CDS             5162..7195
                     /locus_tag="LP468_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2080873.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7206..7646
                     /locus_tag="LP468_001328"
     CDS             7206..7646
                     /locus_tag="LP468_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2080874.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7846..8973)
                     /locus_tag="LP468_001329"
     CDS             complement(7846..8973)
                     /locus_tag="LP468_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080875.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8976..9653)
                     /locus_tag="LP468_001330"
     CDS             complement(8976..9653)
                     /locus_tag="LP468_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2080876.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9917..11683
                     /locus_tag="LP468_001331"
     CDS             9917..11683
                     /locus_tag="LP468_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL2080877.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11698..12135
                     /locus_tag="LP468_001332"
     CDS             11698..12135
                     /locus_tag="LP468_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2080878.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12148..13299
                     /locus_tag="LP468_001333"
     CDS             12148..13299
                     /locus_tag="LP468_001333"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL2080879.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13361..14059)
                     /locus_tag="LP468_001334"
     CDS             complement(13361..14059)
                     /locus_tag="LP468_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL2080880.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14052..15404)
                     /locus_tag="LP468_001335"
     CDS             complement(14052..15404)
                     /locus_tag="LP468_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL2080881.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15627..17027)
                     /locus_tag="LP468_001336"
     CDS             complement(15627..17027)
                     /locus_tag="LP468_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL2080882.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17188..17925
                     /locus_tag="LP468_001337"
     CDS             17188..17925
                     /locus_tag="LP468_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL2080883.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18050..18529
                     /locus_tag="LP468_001338"
     CDS             18050..18529
                     /locus_tag="LP468_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL2080884.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18526..19293
                     /locus_tag="LP468_001339"
     CDS             18526..19293
                     /locus_tag="LP468_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080885.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19523..20092
                     /gene="lepB"
                     /locus_tag="LP468_001340"
     CDS             19523..20092
                     /gene="lepB"
                     /locus_tag="LP468_001340"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2080886.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20196..20798)
                     /locus_tag="LP468_001341"
     CDS             complement(20196..20798)
                     /locus_tag="LP468_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2080887.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20904..21373
                     /locus_tag="LP468_001342"
                     /pseudo
     CDS             20904..21373
                     /locus_tag="LP468_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21479..22063
                     /locus_tag="LP468_001343"
     CDS             21479..22063
                     /locus_tag="LP468_001343"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL2080888.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22066..23139
                     /gene="prfA"
                     /locus_tag="LP468_001344"
     CDS             22066..23139
                     /gene="prfA"
                     /locus_tag="LP468_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL2080889.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23132..23971
                     /gene="prmC"
                     /locus_tag="LP468_001345"
     CDS             23132..23971
                     /gene="prmC"
                     /locus_tag="LP468_001345"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL2080890.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23964..24143
                     /locus_tag="LP468_001346"
     CDS             23964..24143
                     /locus_tag="LP468_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080891.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24165..25190
                     /locus_tag="LP468_001347"
     CDS             24165..25190
                     /locus_tag="LP468_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL2080892.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25365..26609
                     /locus_tag="LP468_001348"
     CDS             25365..26609
                     /locus_tag="LP468_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL2080893.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26762..27709
                     /locus_tag="LP468_001349"
     CDS             26762..27709
                     /locus_tag="LP468_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2080894.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27843..28472
                     /gene="upp"
                     /locus_tag="LP468_001350"
     CDS             27843..28472
                     /gene="upp"
                     /locus_tag="LP468_001350"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL2080895.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28611..28853)
                     /locus_tag="LP468_001351"
     CDS             complement(28611..28853)
                     /locus_tag="LP468_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080896.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28974..29046
                     /locus_tag="LP468_001352"
     tRNA            28974..29046
                     /locus_tag="LP468_001352"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29007..29009,aa:Thr,seq:cgt)
     gene            complement(29165..29803)
                     /locus_tag="LP468_001353"
     CDS             complement(29165..29803)
                     /locus_tag="LP468_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2080897.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29926..30558)
                     /locus_tag="LP468_001354"
     CDS             complement(29926..30558)
                     /locus_tag="LP468_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2080898.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30909..31208
                     /locus_tag="LP468_001355"
     CDS             30909..31208
                     /locus_tag="LP468_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2080899.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10745 a         5484 c         6329 g         8920 t
ORIGIN      
        1 ccttaaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatag
       61 gaggagctat ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc
      121 tctttttata agagttttta ctcattaatt tacaaaaaac aagcaaaatg cgaattttct
      181 cacatttttt ttaacaaaat caaagttatt gcttgaaaga agaagaatcc atcgttaaaa
      241 taaagcttga cgtagagggg agcaagaaat atgaaagatt ttcaattggg ggctgccacc
      301 tatttaaaaa gtgtagccat tcgggtgaaa gaccgagata aaatgattga tttttacaag
      361 aacgttgttg gctttgattt gaaaagagaa gaaaacgaat tagccatttt aggaacagaa
      421 gaagctggaa gtgaaatgtt gctgctggaa gaaagtccta gagcgaatga tcacatgggg
      481 gtgatcaaaa agctgaaccg tttttcattg attatcccta gcacagaaga aatggcagat
      541 atcctttgtc gtatccgtaa aatgaattat ccaatcaaag aagctttaga agatcatgga
      601 cgtatgggga ttttgctcgt agacccagaa gagaatgaat tggaaattta ccatgaagag
      661 aataagaacg accaaagaga aattccagaa acaatggatc aagaagcatt attaagaaaa
      721 tctgaagaaa aattcagtaa actatcaaca ggttcttatt ttgaaaaaat ccatttaaat
      781 gttactaact taacaaaaga acgccaattt cttaatcatg tacttggttt gaaggtacat
      841 aatgaagaag agggcatcca tgtattgaat gaaggagatt tccatgttgg tttgacagaa
      901 gctagcggag gcgcaattga tttgcctaca gatgaagtga ttggacttga ttttctgaaa
      961 ttcatgatcg atactgaaag catggaagga ctgattgctc acttgcagca actatcagtt
     1021 gatttcttct tagacaaaaa gcacacagta ctcacaatct atgatgctat aggaatcgaa
     1081 tggtggttcg tcagtgagcc aaaagaaaag aataaaactg acattcgatg cgacgcttaa
     1141 ctttttcttt cttaacgatt gtcgcatgtc tcgtcatttt atgaacggtc atactatcgc
     1201 ttattctaga gatagaaaga gaaaatagta taccggggga aactgcgcgg tttttcgcgc
     1261 agtttttttg tgtaaaaaag gttgattcct catagattaa gctttaagct tggactgtaa
     1321 gaatctgata gaaaagcagg agaaaaagat gtatccacac acgaaacagc ttattttgaa
     1381 aaagatggaa gaaggatttt atccaggtgt agcagtcgcc ttcataaaag aaaatcaagt
     1441 agaaacattt acagccggct ttgcccaagt cgttcctgaa aagcagctga tgacagaaga
     1501 tctgttgttt gatgcagcct cactgacgaa agtcgttgca accacttcat tagttttacg
     1561 tctattagaa gatggaaaga tagaactcga tcaaccgctt cataaatatc ttcctgaatt
     1621 tgaaaatcag acaatcactt tgcgtcattt actgacacat acttctgata tcaaaacatg
     1681 gataccaaac agagataagc tatctcagga agaattgatc gccgcttatt tgaagctaga
     1741 accaggtgag caactaggaa aagaagtaaa atatacagat gccggtacga ttcttcttgg
     1801 gttgatgcta gaggaaattt accaagaaac tgcagtggaa atctttcaag aacaagtatt
     1861 ggaaccatta ggaatgatga acagcttatt tcttcctttt ccttccaaaa aaatcgttcc
     1921 cacagaacaa ctgccttcgg gtgaggtttt gcgtggacaa actcatgatc cgaaagcaag
     1981 agttttggct gaacatgcag gtaacgcggg tctctttatt gatttgaaag acagcattac
     2041 ttttgtccaa atgtatttga acaagggaaa aatccgtaat ggtcgttttt tagaagaaga
     2101 gacgattgat tctttactgc aagatcaaac accgaaaaaa aatggctatc gttctttagg
     2161 atgggactta aaaaaggatg tagaagacgg tcatgcgatt ctttttcata ctggttatac
     2221 aggtacgttt ttcttgattg atataaaaac acaagaagcg ttgatatttt tgtcaaatcg
     2281 cgtacatcct gtcgatcatc gtgcggagta tctcatatgt cgagatgaaa ttgttgaaaa
     2341 ctttttgaaa gagaaagcgg tattaccgaa ataatgctat aatagctatg aaaaatgaga
     2401 ggagtttgaa ttatgcagga acctatgttt ttaaaaccag tttttcaaga aaaaatttgg
     2461 ggaggaagtc gtttacgttc agtctttggt tttgatatcc ctaacgataa aatcggagaa
     2521 gattgggcga tcagtgcgca tcctcatggt gtcagtgtag tagaaaatgg cgaattcaaa
     2581 gggaaaagat tagatgaact atggtcagaa cacaaggaat tgtttggcca tccttcagaa
     2641 ccagtgtttc cattattgat caagatctta gacgcagaag atgatctatc tgtacaagta
     2701 catccagatg atgcctatgg gatgaaacat gaaggtgaat taggaaaaac tgaatgctgg
     2761 tatatcatcg atgctgaacc tggtgcagaa atcatctatg gtcatcatgc aaagacaaga
     2821 gaagaactag ctgagatgat caaagatggg cgctgggatg accttttgaa gaaagtacca
     2881 gttaaaaaag gtgatttctt ttatgtacca agcggaacga tccatgctat tggtaaagga
     2941 atcatgattt tagaaacaca gcaaagttct gacacgactt accgcgtgta tgactacgac
     3001 agaaaagatg cgcaaggaca aacaagagag ctgcatatcc aacaatcgat cgatgtaaca
     3061 actgtccctg cgaaaacacc agaattacaa atcaaagaag tccgaaaagg gaattcatcg
     3121 atcgtcactt atttagaaac tgagtttttc aatgtatatg agtgggatat taaaggaatc
     3181 acatctttca aaaaacaagc cccttataca ttgatgacgg taatcgaagg agcaggagac
     3241 cttgtcgttg acggaaaaac atatccatta gaaaaaggaa caagctgtat tattccaaat
     3301 ggcgtttctg agtgggcggt ccaaggtgaa ctagcaatca ttgcgtctga accaggcaaa
     3361 tagttcccag atagctgaaa gcagcagacg gtttttcgtt tgctgctttt tctacataaa
     3421 atccgtccat caataaatag aagtctggtg aaaaagatgg aatacaaatg gaaagcaaac
     3481 aacagcagtc gcgtgtctat gaaacaactg agaaaagctg gacatcactt aaatgaaatg
     3541 atcatgccaa atctaagtct gtttatcgct tggggaatct tgtcattagc aacaaaaggt
     3601 gtgtctggcg atttgcacac cacattagaa gaggtatgcc attggatgat ccagctgctt
     3661 ttacccatct tgatcagtta ttcaggcggg aaatcggtag ggggacaaaa aggggcagtc
     3721 gccggtgcaa ttgcttcttt agggttgatc gctcgttcca atgctccaca aatcgtagga
     3781 gcgatgatta tcgggccgct tgccggcatc gtatatgaac aatttgtttc tagattccat
     3841 gtgaaattca aggctggata tgaaatgctt gtcagcaacc tactagtagg actgactggt
     3901 agcgttattt gtataattgg aatcgttttt attgaaccag ttttaaatag tgttcacttg
     3961 ttgctcgcct ccgttgtgtc ttggctagtc acaatgaatc tgttaccact tgtcagtctg
     4021 atcttagaac ctctaaaagt actatttttc aataatgcaa tcaatcatgg tgtattgaca
     4081 cctttaggaa tcgaattctc acaaacagtc gggtactctt ccttattttt gatggaggca
     4141 aatcctggac ctggtttagg gatcttactt tctatccttt gttttgcaga aaaacaggaa
     4201 aaagtaaatg cgagtggagc attgatgatc catgcgattg gcgggattca cgaaatctat
     4261 tttccatttg tcttgctgcg accgtatcta tttttagctg taatggctgg tggggcaagc
     4321 ggcacgttga tatttcaatg gttagatacg ggattagctg cacctgtatc gcctgggtca
     4381 ctactcgtga tttttgccaa tgcgccttat ccacaactag ctggggtaag tatagggata
     4441 gcaatcagta catttgtgac cttcatttgt gcagcgatac tattgaaatt accaaataaa
     4501 gaaaaagaga acaaaacggt caaagaaagg ggagaaatct tggaaccatc tatcattcat
     4561 tccgtcattt ttgcttgcga ctcaggtatg ggatcaagtg ctatgggagc cgccctgctg
     4621 aaaaagaaat tagcagcaga aaaaatcgat ctttctgtcg gatacagctc tatctatgaa
     4681 ttgaataacc aagtaaatca gctggttatc gtgcaacatg aactagcggg tcttgcaaga
     4741 gaaaaagtac ctcaaagtca aatctatgta ctggatcact ttttggaaac agatatcttg
     4801 ctgtcacgaa taaaagaagc gatccaattt ccaaagcggg aagaaaaaaa agagatagca
     4861 gatatcacag aacaaaaaac gtcgcctgct aatattgtat ttttgtataa aaacaacaga
     4921 cgcggctcac aaactatggg catgacgatt ttaagtcaat tagcaaaaaa agcgaaaaaa
     4981 cagtttgtta tctcaaaaga atcaatagaa aaaatcaaaa tccaagaaga aacgatttat
     5041 atcgcacaaa gagaactagc tgtaactgaa cagctagaag aaaagatccc tcggctagtt
     5101 ctagttgaac attgggtagc tacgaatgaa tacgaaaaac tcgtgaaggg agaaatataa
     5161 gatgtattta tcgcccagag aaaaacaatt attagcagaa tttctcagta gcccgtcacc
     5221 tgtatctatc caaaaaatga tgaatttatt gaaggtcagt aaacggacta tttaccgcga
     5281 attagataat cttgaagtct cattgaaatc ggtaaatgct tctttgaaaa aagcagctag
     5341 aggctcattt gtcattgagg catcagaaga agtattagag caattaaaag aaaatacaga
     5401 tgggaaaagt aatgacttat ccactgctaa acgacaacac gcgattttag ccgagttgtt
     5461 actgacgaca gagccgttga gtcttgctca tttcatggaa tcatatcgca tcagtaatac
     5521 cactttttat gcagatatca aacagttgga agaaagtatt cgccaactgc ctttggaaat
     5581 cattcggaac cagggatacg agatcgaagg accggaaaaa taccgccggc ttctgacagc
     5641 gaatgtatta gaattagaaa tcaatgaata tgaacttttt catagtattt ctttcgatgc
     5701 atcactgaat tatttttttc gattcgttga tccgcaacat ctatctcttg cacgcaaagt
     5761 aatcggggaa gaattgatcc aaaaaaagac caatctaagt gatagaaagc ttgaacattt
     5821 ggttttgatg ctgacattga cgatggagcg tgtgacgaaa aatcatttac tgacaaatga
     5881 gacatataat agtctggcaa acaaagaatt actacagaca gctaaacgat tgttttcacg
     5941 gatcgcttct gagacaaaac aactttatcc agtaaatgag atcgtctttt ttgcaggatt
     6001 attaaatgac ttcacgaact catttgatca gaatttcttt gaagagacgt tcgatacaca
     6061 gcttgcttat ttagtaaaac aactgattca agaagtaagt gaagagacga atgtccattt
     6121 ttatgaagat gaaactttgt acaaaatgct gttgactcat ttatctggtg tgttttcaag
     6181 agccgtttta caagaagaga cactgaccaa tccgatttta gaaaaaatca tggttcaata
     6241 cgaggaagtt gcgaatgcaa tccgtaaagc agtagagcgg atttttcaag aaaaaaaatt
     6301 atccgaagaa gagatcgctt atatggtcct tcattttgcg aattcattgg aacgaagtcc
     6361 gaaagaaagc aatatcagta ttgcaggatt ttcgccaagt ggattagctt ctactagcat
     6421 gttggaacta cgattgaaaa ggtattttcc cttcatccaa caaattcatt tctatcggat
     6481 tgctgattta aaaaaaatcg atttacaaga agaatatgat gttgttattt ctacatctat
     6541 tttaccagga tacggtggaa aatatatttt agtctccccg ctactgctag aagatgaagt
     6601 caagcagcta aaagaagctt tttcgcatat tgagaagaaa aaaaggcaaa aaattacgta
     6661 taacagcaat aacgagtgga tgatagaaga tacttatgag gaaacaatgc atttcatgga
     6721 tcaaatcaat caattactcg gtcgtttttt tatccaagaa ctggataatc ctgagacgat
     6781 ttccgaaacg attcgcagct tatttcctta ttttcctgaa ggactagtaa cggatgaaga
     6841 ggtggttcat cgccggctgc ttaagcgata tgaacaagca cctatcggta ttcctcatac
     6901 aaatatgggg ttattccata catccagctc attgatttct aaaccgatct tttgtatttt
     6961 caatttgaaa catccgttga ccattgaagg gatggataga cagccagtcg atttgtcccg
     7021 tatgttagtt atgctggcgc cttcgccaat ccaagaaaaa gacgggattc ttttaggaaa
     7081 gatcagtgga gcaatcatca tgaatgactt gaacaccgag atcttccgct caggaaataa
     7141 agaaatcgtt tatcagttgt tagcgaaaat cctgattgaa gaaataaaga aatgaaggtg
     7201 aaaagatgat acagctacca gcagaaaaaa tattgctcga tcaatcctat caaaattgga
     7261 aagaagcgtt gaccgagatc ggccagtgga tgacccaaca agggggaatc aaaccggcat
     7321 atatccaatc aatgatcgaa agacaagaaa aagcgagtgt ctatatcggg aatttcgtag
     7381 ccttgccaca tgggactgac aaagatgaag aagtagtaga agaaggaatc tatttagtcc
     7441 aagtgcctga tggtgtggac tttggaacaa aagaggaacc aaaaatcgcg acactcttat
     7501 ttgtagtggc tttaaaaaaa gaacatcagt tagcggtgct ccaagattta gcctttttct
     7561 gttcagacat cgaccaagta atggcgctca gtgatgcgga aaccattgaa gaagtccaaa
     7621 tgatttttga acatggacat atataaccaa tgttcacagt aaaaaaagct gccttgcatc
     7681 aagtaataac ttcaaccaag ataaaaataa gaggagctat ttttgttggg aggttcttat
     7741 tactgcggat gcaagctttt gaaaactatt tattctagaa aaccgtttat ttgaaatagg
     7801 ggacggtgac aaggtttttg tcaccgcccc tattattttt gtgttttaat agctcttttt
     7861 tatatagata gtgcccatac ctatgaataa taaaacgata ctccatatac caagtgtcaa
     7921 gataccattc atgaaagtaa cctgttctga agctagtggc gagaaaatat ctcctcctat
     7981 gatcacattt tgaaaatcaa cataagaagt tggcaagtaa tgactgattg attctatcca
     8041 tccaatcgaa gaaaacaagc gatactctgc taagaaaaga caaagaagtg tacctaaaag
     8101 attgactaga gaatgttcaa ataaagcaga tagaagaaaa ctgattgtac ttaaaaagag
     8161 cacccacaac aacaggaaca gaaagctctg gaaaagatac tcatacatcg gcaggattcg
     8221 tatctcctga ccaatgatcg ttcctacagg ataacggaag tctcccaaac catttttgat
     8281 tattactagt atagagacga tcaaaaatgg catcacgaga cttagcatag ctgcaccata
     8341 ataaatggta aaacggatgc tatgtttctt taccatacta tccggtaata gattgactag
     8401 agagattacc tgctttcttt tttcataaga gatgatggaa gaaagaaaca aggcggttat
     8461 acataaaatc aaaaaactag aaatcattcc tgaaaaaata ttttcgtagt aatttgctaa
     8521 agagagatgc gctggcaagt caaaaataga atatctttgg atctgatgtt ctttcatata
     8581 acggagcaac tcgacacgtt tttgttgttc aatgattgga attccttgtc tttgaccaga
     8641 aatcagtcga tccagtatat ctttttcata atgataagtt gcttcgacca tttgctggac
     8701 attccctgtg ttttttgcat gtaagattgc ttcgatcagt ttgttgcttt tctctaaact
     8761 ttccacaaat tctttctcat tctcatcttc tttcaacgtt tcaatcaaac gttgcatctc
     8821 ttcatagtta tgattcagtt catcgaattc tgtataagca agtttatgat caaaaaaaag
     8881 tgggaatgca aagagcacga ccaacaatag aggaaataaa aagtttactt tgttttttag
     8941 taagagattg cgttcaaatg taagtaaaga catagttaca cctcatataa tttacgataa
     9001 atagctaaaa tctcttccat atttgaggat tctgtgacga tttctccatt ttttagaaaa
     9061 catgctttag aacaaatcga ttggatattc gcgatagcgt gggaagaaag aagaatcgtc
     9121 ttcccctctt tctgccattg tctgatgagg ctattcaaga tatcaatact tcctgggtct
     9181 aatccgttca acggttcatc gaataacatg acagatgaat cactgatcaa gtaagcagca
     9241 agcaagacat gttgtttcat tcctagagac atttttccaa tcggcaaagt aaggtactca
     9301 gtcatcttca atcgttggaa aacagtttgg cattctactt tgctctgcca atagtatttg
     9361 atcaaagtca aataatcaac agccgataga tagtcggata actgattcgt tgattctaga
     9421 aaaaagaaag accggcgata atctgtataa gcagtaggag agatgttgtg aagggacaat
     9481 tgatcataag ttgttggcag cagttgggca atgccattca gcaaagttgt tttgccaaat
     9541 ccgttcgggg caatcaaagc agctacttct cctgattcta ctaaaagatt caattgtcga
     9601 atcacacgtt ttttaccacg tttcatgttc atgtttttga tcagtaatgt catagatagg
     9661 cctccaatat aaaatttaat aacataatag aatggaaaac atctaaatta aatgctaaca
     9721 aaagttattg tttgcatatt ataaaaaaat taaaataaca gttttattta aaattgaagt
     9781 tttctgatac cgaaatcttt ttattttgct gacatactca aacctttggc acaaagtttc
     9841 gtgccaaagt acgactattt ctctttttag taagcggata caattagagt atcaaaagga
     9901 gagagggaga gacaaaatgg aacggacgat tcccaaaaac aacatttcgc taaaagcgag
     9961 ggtacaaaaa ttaggcagta ctttatcaag catggtcatg ccaaatattg gagcactgat
    10021 tgcctggggt gtattaacgg ctctatttat cccagatggt tatttaccaa atgaggcttt
    10081 cgctaccatg gtaagcccaa tgctaactta tctgattcct ttattgatcg gttatactgg
    10141 cggaaaagta attgctggtg accgcggatc agttgttggg gcaattgcaa cgatgggtgt
    10201 gattgtcgga acagatattc caatgatgct aggcgcgatg atcatgggac ctcttggtgg
    10261 atatgccatc aagaaatttg atcagctatt ccaaaaacgg atcaaatccg gttttgaaat
    10321 gctagtcaat aatttttcag caggtcttat cggttttgga ttagcgttat taggtttttc
    10381 tgcgattggt ccagttgtcg atgcattgac tcaagcaatg gcaaaaggtg tagagatcat
    10441 tttatctgcc catttgattc cattgacaag tatttttatt gaaccagcaa aaatcttatt
    10501 tttgaataat gcaatcaatc atgggatttt gacaccattg ggaactgaac aagtagcaga
    10561 ggctggaaaa tctattctat tcttgcttga agcaaatcct ggtccaggac ttggcgtatt
    10621 acttgctttt actttgtttg gcaaaggagc agcaaaatct tcagcaccag gagccatgat
    10681 cattcacttt ttaggcggga tccatgaaat ctattttcct tacgttatga tgaaaccgtt
    10741 attattctta tcagttatag gcggaggaat gtcaggaagt ttcattttcc aattgatgga
    10801 tgctggacta agagcgccag cttctccagg gtcgatcatt gcgattctag cgatgacacc
    10861 gttcaattct taccttcctg ttattttggg cgtgattgtt gccgcagctg tttcgtttgg
    10921 tatttctgca gtaattttga aagcggatgc gaaagataca aatgaagact tcgaaaaatc
    10981 tgttcaagag acaaaggcag ctaagcaagc ttccaaaggt gcccaaggta ttcctcaagg
    11041 agctacattc tctggcgtac aaaaaatcat ttttgcttgt gatgcaggaa tgggatcaag
    11101 tgcgatgggc gcttcgatct tgagaaaaaa agtacaggaa gcagacttgc ctcaaacggt
    11161 gaccaatcaa gcaatcagcc aactgacaga tgactcgaat acattgatcg ttactcaggt
    11221 cgaactacaa gaaagagcaa aacaaaaagc accgagcgcg cgttttgtct cagtagaaaa
    11281 ctttttgaat tcacctcgat atgatgaaat cattcaagaa ttaagcagca agcagaaaac
    11341 atcagtttct gaaattgaga atgagccagc agaagagttt ctttcagcaa acatcaaaca
    11401 aatcaaagag attctacttg tccacgatga tcgttccgga tcagcaacaa tggggatgac
    11461 cgtgctcaaa gatatattag acaagaacca tttaactatc ccgttaagaa aagtcaatat
    11521 ccaagattta aaagatgaac ctgattcact gatcgtagcc aaagaaagtt tagcggaaaa
    11581 agtacagatg gctgcacctc aatccattca tttatcagtc aacagcatgg tcaatccgca
    11641 aaaatacgaa tcgattgcac aatatttgaa acagacagct taagggagga aaacagcatg
    11701 caaagtttgc cattcgacat gatcgagctc aatcgatctt ttaaaaccaa agaagaagcg
    11761 atccgctatt gcggtcagat gcttgtagaa gcagggtgcg ttgatgagga atatatcgat
    11821 gccatggtag atagagacaa aatgttatct gtttatatgg ggaattttat cgcgattcct
    11881 catggaacag atgaagcaaa aaaatatgtg aaaaaatccg gcatctgtgt cgttcaagta
    11941 ccagatggtg tagattttgg taccgaagaa gaagaaaaga ttgcgactgt tttgttcggt
    12001 attgcaggag tcggagatga gcatttgcaa cttgtacagc aaatcgcact ttattgcagt
    12061 gatatggaca atgttgtcca gctagcagac gcgctcagca aagaagaagt aacggaaaat
    12121 ctagcaattg cttaaggaga gagaaaaatg agagcagtac attttggtgc aggaaatatc
    12181 ggtcgaggat ttattggaga ggttttggca gctaatggat ttgagattac tttcgtagat
    12241 gtgaatcaca cgatcattga tgctttaaat gaaagaaaag aatacgaaat cgaattagca
    12301 gatgaatcaa aagaaaaaat cactgtaaaa aatgtcaaag gaatcaacaa tcaaacaaat
    12361 ccagaaaaag taatccaaga aatcgctgaa gcagatttag ttactaccgc cattggcccg
    12421 aatatcttac cttttattgc tgagttgatt gcaaaaggta tccaagaaag agaaaaggaa
    12481 ggaagcacaa catctttaga tatcattgcc tgtgaaaata tgattggcgg ttcagcattt
    12541 ctagaaaaag aagtgtataa atatcttccg gaaacatcat ttactgacaa atatatcggc
    12601 tttccaaatg cagcagtcga tcgaatcgtc ccattacaac accatgaaga tcctttattc
    12661 gtccaagtgg aacctttcaa agaatgggtc attgacgata gccaaagaaa aaataaaaaa
    12721 atccaattaa aaggggtttt atatgtagat gatctagaac catatatcga acgcaaacta
    12781 tttagtgtca atactggtca tgcgactgtc gcttatacag gtgccttgtt aggttaccag
    12841 accattgatg aagcaatgca agatgcgtta gttgtggcac aattaaaatc agttttgcag
    12901 gaaacaggaa gtttgctgat tgccaaatgg gggtttgatg cagagcagca tcatgcgtat
    12961 attgaaaaaa tcattcatcg cttccaaaac aaaaatatct ctgatgcgat cacacgtgtc
    13021 gctcggacac cattacgtaa gttaggttat caagaaagat ttacacgtcc agtgagagaa
    13081 ctacaagaac ataacttgac ttgcccacat ttgacggcaa caatggggat tatttttaat
    13141 tactatgatc ctgaagatga acaaagccgt caattgcatg aaatgaagat ccatgaaaac
    13201 ttggaacaat tgattcaaga agtcacagga atcaatgatc cgaaaacaat cgggaatatc
    13261 aagcaaaacg tgaaccgtta tgccaagcaa gtcgcttaaa ataggatacg aaaaagggga
    13321 atgtgacgaa atttttgtca cattcccctt tttcgaataa ctaggctgtt tgtccttcaa
    13381 gatagggcag atccaattct ttaccgtaac gttgttctaa agctaggcgg atcaaacgag
    13441 ctgccaggtt ctcatttctt gcaaggatag gtccatggaa ataagaaccg aagacatttc
    13501 ggtaaatgac accttcagat tggtcttcac cattatttcc ttgaccttgt accactttcc
    13561 ccaaaggtcg ttcaccttca cctaagaaag tccgaccatt gtggttttca aatccataat
    13621 aagtttcatt gaattcttcg ttatggataa cgatatcacc gataaaccgg ttattttcct
    13681 gacttaacgt gtagtgatcc agtgcactga ttccttggat cttttctcca ttagctccca
    13741 tgtagtagtg acctagcaat tggtagccac cacaaatggc taacatgacg ccatcatttt
    13801 cgatatagtt gatcaaagaa tctttctttt tctggatgtc ttttgaaatg attaattgct
    13861 caaagtcttg accaccgcca aagaaaacca agtcatattt atcagcatca aaaggttcat
    13921 gtatactaac gatctccgta tggcaagaaa cccccatttt ttctgctata tatttcaaca
    13981 tcaaaaggtt tccgttatca ccatatgtgt tcatcaaatt tccataaagg tgggcgatat
    14041 tgagttcata attagccacg gttcattcct cctttgataa atccttgagc agctagttct
    14101 ttacgaagct gcaatacagc agtgtaagta gctaaaatat agacatgctc agttggcaat
    14161 tctttgattt tttcgattac ttctggtaat tcttttgttt ctgtcaattt attttctgga
    14221 atcccggcaa cttttagacg taaagtcata tctgtatgac ggtctcctcc agaaataaca
    14281 gctgggatat ccatatcggc aaagttttca aaattaccat cccaaatcca gctgacatcg
    14341 attccgtctg cgtaattggc atttaataaa gccactaaag aaaatggata aggagctaga
    14401 ccaatcatat cgattacttg attgatacct acaggatttt tgacaagtac taatgtacat
    14461 tttttcccat tgatattgat gacttcttgt cggccgaata ctttctcgtc atatcctaaa
    14521 ccttgtttga ttttatcagg atcgacattg aagtactctg ccactgcagt agctgctaaa
    14581 gcattgtaga cattatacat accgccaact tcgattccgt attcatgacc atcgatcacg
    14641 aaatctgctg acacattgtc catccgtacc atatcagtta atcgataatc caattcagga
    14701 cgtttgaagt cacaatttgg acagtaatat ttccctaagt ttgcataagt gatcatttta
    14761 taatgcaaga tgtgatgaca atttggacat aagacaccgt ctgtattgta atgagccatt
    14821 tgttcacgat cttcttcatg gtcaaagcca taatattttc taggattgac tgtttcgata
    14881 gaattgaaga ttggtgaatc accgttactg ataatcgttg catttggtga ctttgcggca
    14941 ccgtctacaa tcattttata ggtcgtatag atttctccat accgatccat ttgatcacgg
    15001 aaaatatttg taaataagaa cagttctggt ttcatatatt ctgtgacttt gctcaaactt
    15061 gcttcatcta tttctaggac agcaaacttt ttctgtcctt tttttggttt tgcctgcaag
    15121 aaagtcgata caattccctg taccatattc gcaccagtag ggttggttag aacttcatcg
    15181 aattgctggc gcaaaatatt gactgttaaa gcggtagtca atgttttacc gtttgttccg
    15241 gtgacaacga cgacttggta gtcttttgcc aaactatcta gtatatgtgg atcgactttc
    15301 agcgctagtt tacctggtaa acttgatccg cctttaaaaa aagtttttaa tgcccattgc
    15361 gacgtttttc caactgcaat cgcaaaatga ctgcgtattc ccattatgta acctccaaaa
    15421 acgatttgct gacgaataaa ttcaactaat cataccatat gttgaaaaaa aggttaaatt
    15481 gcttttctta ttcttaagaa aaggttacgg ctgaaagtgc atgaaatcgg acaaaatcgc
    15541 atgatttaac aaaaaaacag cttgaaacaa aatgattgtt tcaagctgct gtgattttat
    15601 tattccctct tacctatatt cccattttaa ccgataataa ttttctcgct tggatattca
    15661 tagcctagat ctcgtgtttc ttttggcacg aataacatca atgtatatag cattccgatc
    15721 cgcccaataa acatcagtgt agcaatcgtg attttgccca caacagacaa gtctccggta
    15781 atccctaaag ataaaccagt tgttccaaac gcagaagtta cttcgatgat gatcgagatc
    15841 agcgtttgtt cttctgtagc agataaaaaa acgatacaaa agaaacacat accaagagaa
    15901 agcataaaga caacgactga ttttcgcaca tcatcttgat cgattctccg tccaaaaata
    15961 ttgatgttat cttcactttt gaggaaggaa tatagataca aaccgatgat tgctacagta
    16021 gttgttcgaa tcccgccgcc tacagaacta ggactgcatc cgataaacat cagtaaagaa
    16081 aaaatgatca gtgttgtgat ttgaaaatca cccaaatcgt gaatctgcag accagcatta
    16141 cgagtcgtaa tcgaataaaa catcgaattg atccatttga cactcatatt ggaatcttgg
    16201 aataaatggt ccttttccaa tagataaatc aagacagttc ccgaaacaaa caagataaca
    16261 aaagctaaca cagctaattt ggtaaacaag gaaaaacgaa acggaagctt cgcattggaa
    16321 cgtttgtata atagccattc ccggcactcc atcaatacag gaaaaccaat tcctccgaca
    16381 aaaatcaaaa acatgatcag gatcaagaaa aaatagtcat gtgcaaaggg cttgatggaa
    16441 tccccagtga cgtcaaaccc agagttcgtg acagccgata tcgcctgata aaaaccgtaa
    16501 aaaacggcat cacgccaacg atcaaaatag cctctgtaat aaaaataaat agaaaagaat
    16561 gtcccaaaaa gtaattgaaa ccagattaaa atagcaaaag tgatccgaat cagtcggacg
    16621 ataccagaca aacgcggttg attcatatcc gtcatgatca gctgtcgctg tttcagtgtg
    16681 atccgtcgtt tagaaaaaat gacaaaagca gtagaaatca tcatgatccc caaaccacca
    16741 acttgaaata atatttccag cagtataata ccgttatcat tgaacacaga attgatatca
    16801 aaagtcgata gtccagtcac actcactgta ctgattgcca tgaacagcat gtccacaaaa
    16861 gaaacatggc tatctggttc gcgaaaaatc ggcatataaa atagaacgag tgataagacc
    16921 gtcatcaata tataataaaa aacgatgatt tggatcgatg agaaatgatt ggcagcaaac
    16981 ttctgtcctc gccgctgcag ccttcgaaag aataaatcaa catgcacagt actatcctcc
    17041 tgacaatagt cgtttctacc agtatacaag gggaattagg aatactcaaa gaaattatca
    17101 aacagataac aatacagctt tcgattaaaa tagaaatggc ttataataag gaaaatccta
    17161 gaaaaaagaa ggaggaggaa taacaaattg attaatgctc aacaaatcgt agaaaaaatg
    17221 aaaaatcaaa aaataaatta tgatacagtt ctgaaaaaaa tgatcatgca atgggagaaa
    17281 gaagaagtaa agcctaagat attaatacat acatgctgtg ctccttgcag tacgcacaca
    17341 ttggaattca tgtctcaata tgcagagatc acgttatttt tttcaaattc gaatattcat
    17401 cctaaaagtg agtatttgcg aagattacat gaacaaaaac gatttgtaga ccaatttaat
    17461 gagaaaactg accatcatgt tgcgctaatc gttgatgaat accgtccaaa tgaattcacc
    17521 aaaatggttt taacaaacca tcttgaaaac gaaaaagaag gtggtgctcg ctgcagtgca
    17581 tgcttcaata tgcgattaga tcttgttgcg caaaaagcgc aagaactagg atacgattac
    17641 tttggaagtg ccctgaccat ctcgccaaag aaaaatgcag ctttgatcaa tcagatcgga
    17701 atggatatcc aaaagattta cgggacacaa tacttgccaa gtgatttcaa gaaaaacaaa
    17761 ggctatgaac gctctttgca aatgtgcaaa gagtatgata tttatcgcca atgttattgt
    17821 ggttgcgtgt tcgctgccaa gcagcaagga tgcgatctga aagaaatcaa tcgggaagca
    17881 aaagcttact taaaaacatc aaccgtagtt tttgaggaaa attaaagaaa tctttcggaa
    17941 aaacgtaaga aaaaaataaa gaatttatgg tagaaataag gtagactgta taatttgtcc
    18001 gtagtaaagt aaggaaacaa gaataaattt caatgaagga agagataaga tgcgaaaagt
    18061 agcacctatt ttgaagccaa tcgctgtatt aacaatctcg acgattgtcg cgactactac
    18121 aggtattgtg aatagttcca gctaccgtgc accaagttca agttctagta ctgtagaaga
    18181 aacaacacca actacttcag tctcgacatc tgaaccaaca acaacggaaa gtttgaatga
    18241 aaccactacg acaagtacat gggacgatac aacaactagt tcgtcgtatg atgagacata
    18301 tacaactgac agctcaagcg aaacaagtaa tacggtacca gatggcactc catcggattc
    18361 aaccaatcca agtacaagtc cggatacaag tgctagctcc gaaacgatac caagcagtac
    18421 gactgtagat gataacacgc aaaatgatga tgcagcacgt acagcacagc aaaaccaaga
    18481 ttcaggaaat acccaaacgt ataaccagca agcaggtgat tctcaatgac atttttacta
    18541 gaccttatca acggggtgca taaattcctt ggctatttag acatcagtcc taaatatctt
    18601 aaccgtggat atacgatttt aagtgtgatt cccacgcttt atttattgag aattgtttat
    18661 ggactttggc aaaaccaaaa ctatcttcaa tttttcttat atggacttgc atttctagtg
    18721 cttgtttatt ttactgtttt aaatgtattt tattactttt tagataaaaa cacgaaagcc
    18781 gatgtcactc agctttttgt gaagtattta cctgatgaag cgttcaacat ccagacagaa
    18841 gaatcgatag ataatggaaa ttcgatcgat aaagtgaata cacaagaggt catggtttct
    18901 tatgacgaag attatcaatt gaaattagcc gagaatatgc ggtatttgat tggaaatggt
    18961 gagatcaaaa caaatgaact cggtcgcatg gatggatttc tggtcgatag aaatacattg
    19021 tatccttatt actatgtcaa gaaaacagga gagaaagagt atgttctaaa tattggacga
    19081 agctactcgg acatggaaaa agtagggacc attcgacttg actcaacaga agacacattg
    19141 gaacctgtcg gattgttcat cgtcggcggt gattttgtca aagacgggtt acgctatcat
    19201 gagccttatc gtctgaaatt gattgcaaaa aaggcacagt cgcaggaaga accagtggtt
    19261 tatagtcgta gccaaagaag aagacattca taatgtgatg aaacgccgtg tatcagtggt
    19321 tgcgataaaa acgtttattc ggaataaggg ggatgtgaca cgtcttttgt cacgttcctt
    19381 ttttatataa cgagaaagat aagacgaaca catcacttat tctttccttt catttataaa
    19441 cattgtagaa taaagaaagt acaacgaagt attgtgaaaa aacgtaataa ataacgagga
    19501 aaatacaagt aggaggtaag ctgtgaaaga atttttgaaa aattggggga ttttgatcct
    19561 tgtattagcg gctattttat tagctagagt gtacgtgttt acaccagtta ctgtaaacgg
    19621 gcattcgatg gaccctacat taagtgatgg acaacgattg atttcatcta agatctcaaa
    19681 ctatgaacga atggatatta ttactacaaa ggaaccgggg gatgaagaac ggatgattgt
    19741 taaacggatc atcggtatgc ctggagatac agtcaagatg gaaaatgacc agttgaccat
    19801 taatggcaaa aagtatgatg aaccttatct ggatgagttc aaaaaagaat tttcagaaga
    19861 taagttacaa ggagaatatg cttatagctc aggattccaa gcacaagcag aaagttcatc
    19921 cacctttacg agtgactttg aatatactgt gccaaaagga aagtatcttg ttctaggcga
    19981 taaccgcttg atttcaaaag acagccgaat gtttgggtta gtcgacaaag atatgatcca
    20041 aggaaaagtt gttttccgtt attggcctct ttcagaaatt aaaatcatgt gatgaaaaaa
    20101 taaaaagaag ctgtgacatg ttttttgtca cagcttcttt ttccgaaaat tccttcttat
    20161 ttcttggagt tgctcacttt ttttgcaatc tcattttaag ctttttggct gatggataag
    20221 aaaagcgaag cgtttttgtt cataaatagc ttttccccac gatggaaggt atgactagta
    20281 gcagagacaa agcccgtttt ttccaatcga ttattcaatt cttcttggct aaagccatta
    20341 tggactttcg gatgactaat ttgttcattc ttgtcaaagt ctacgatgat caattgaccg
    20401 ccaggagcta aaatttcata aagttttgta agaatattct ccgtatcagg aatgtgtaaa
    20461 agtacaagtg atagaaggat gagattagct tggacagcag gaaattcgac agaagcatca
    20521 gcgtggatcg ttcggacatt tttcagatct gctgcttgga tcttttcttc tgccattttc
    20581 agcatagttt ctgaagcatc ggcaatgatc agttctttga atctttccgc aagcggtaaa
    20641 ctaacaagcc cagttccgcc tccgtaatcc agcaggactt tttggtggct gtcgcgcggt
    20701 agataagtag ttagttcttc gcgaataatc ttggctaatg cttgacggtc aggggaatca
    20761 taatggttag cgatggaatc aaaaatattt tttgtcatca aatagctcct tacgtaaaac
    20821 tttgaaattt taacttatta tagcacgtga aaagaaagaa agcatgctat actcaattca
    20881 aaaagggaga atctagaaag aatatgccga tatcgtttgt aaaagataga gaggaaaaag
    20941 gaaagtgtgt ccgagaaata ttactagact tgcctgagtg gtttgggctt cctgaatcaa
    21001 cggaaaaata tatcgaggaa tcaagtaaac tacctttatg gtgtgaaaaa agaaaagaag
    21061 aatatttagg ctttatcact ctttcacaga caagtgaaga tactgccgaa atctattcta
    21121 ttgtatggga ataaaaaaag actatcatca ccaaggatta ggaacaaaac tttttaaaga
    21181 agcagaaggt tacgcagcaa aacattacaa atatttgcaa gtgaagactg tagacgaggg
    21241 gcactactct atatatgatc aaactatttg tttctacgaa tcattaggat tttcaaggtt
    21301 ggaagttttt ccaaatttat gggatgaatg gaacccatgt ttagttcttg tcaaaaaatt
    21361 ggaacaaaag tgagcaatag atttaatact aatctgtgct tgatgaaaat tctcactgta
    21421 aaaaatgctg aaaatcaagt ataataccat aggaacaaac tggaaggtga aaaagagcat
    21481 ggcacaacta ttttttaagt atggcgcaat gaatagcggc aagacgatcg agatcctaaa
    21541 agtcgcacat aattatgaag aacaaaataa gccagttgtc ttaatgacaa gcggtattga
    21601 tacaagagat ggtttaggcg ttgtttcaag ccgaatcgga ctgaaacgta atgcgatgcc
    21661 gatatttgaa gaaacagacg tatttgacgt aattcagaaa atggaaagca aaccctattg
    21721 tgtgctgatc gatgaagcgc aattcttaaa aaagaaacat gtcattgctt ttacgagaat
    21781 tgtggacgaa ttggatattc cggttatggc atttggtttg aaaaatgatt ttcgaaacga
    21841 gttatttgaa ggatcaaaat atttattgct ttatgcagac aaaatcgaag aaatgaaaac
    21901 aatctgttgg ttctgccaca aaaaagcaat catgaattta cattatattg atggaaaccc
    21961 tgtttatgaa ggcgatcaag tgcaaattgg cggaaatgaa gcttattacc ccgtttgtcg
    22021 aaaacattac tttcacccat caatgattac agaaggagaa taagcatgta cgatcaatta
    22081 caagcaattg aagaccgtta tgaagagctt ggagaacttt taagtgaccc agaagtgatt
    22141 tctgatacaa agcgttttat gcagctttca aaagaagaag caaacacgcg cgaaacagtc
    22201 gaagtttatc gtcgttataa agaagtagta caaggaatca ccgatacaga agaactgctt
    22261 ggtgaaaaac tggatgatga aatggctgaa ctagcaaaag aagaattatc tgaattaaaa
    22321 aaagaaaaag aagtcttaga agaaaaaatc aagatcttgc ttttaccaaa agatccaaat
    22381 gacgataaaa atatcatcat ggaaatccgt ggagcagcag gcggagacga agcagcatta
    22441 ttcgctggcg atcttttcaa tatgtaccaa aagtatgctg aagcacaagg ctggaaaaca
    22501 gaagtgatgg aagctaacgt taccggaatc ggtggatata aagaagtgat catgatgatc
    22561 accggagaca acgtatattc gaaattaaaa tatgaaagtg gtgcgcaccg cgtccagcgt
    22621 gttccttcaa ctgaatcgca agggcgtatc catacttcca ccgcaacagt tgtcgtgatg
    22681 ccagaagctg aagaagtaga gatcgatatt gaagacaaag atatccgtac agatatctat
    22741 catgcttcag gtgctggcgg acagcacgtc aataaaacag catctgctgt acgtttgact
    22801 cacttaccaa cagggatcgt tgttgctatg caagatgaac gttctcaaat caagaaccgt
    22861 gaaaaagcaa tgaaaatctt gcgtgctcgt gtgtacgata agatccagca agaagcacaa
    22921 agcgagtatg atgccaatcg aaaatcagca gtcggaactg gggatcgttc agaacggatc
    22981 cggacgtata atttcccgca aaatcgtgtg actgatcatc gtatcggatt aactatccaa
    23041 aaattagatc agattttagc agggaaatta gatgagatcg ttgatgcatt gatcatgtat
    23101 gatcaaacat caaaactgga agctatgcaa aatgggtaaa atgacctatc gagaagtcct
    23161 gtcacgggct tcttcttttt tagaggatca tgggaaagaa gcatatagta tccaattttt
    23221 atttttggaa cgaaaacaat ggaaaaaact tgattggctc cttcatatga acgaagagat
    23281 ttcagaagaa gaacagcggt tgatcgaaac cgatctgcga cttctgcttg cagatcatcc
    23341 acctcagtat ttgctaggat atgcagattt ttatgatcat cggttaaagg taactgaagc
    23401 aacactgatc cctcgaccag aaacagagga gttagtcgaa tggtgtttag acgagacgcc
    23461 tggtgtaccg ttagaagtga tagatattgg gacagggact ggagcaattg ctattagttt
    23521 gaaagcagca agaaaaaatt ggcatatatc tgctgtggat ctttcagaag aagcattaga
    23581 agtagcgaaa gaaaatgctc agaaagaagg aacgaaaatc agtttttatc atggagatac
    23641 attaggacca gtaatggatc agcaatttga tgtgattatt tctaatccgc cgtacatcag
    23701 tcggaatgaa tgggaactga tggatgaaag tgtccggtca ttcgaaccta aaatggccct
    23761 ttttgctgag aacgatggat tagctattta tgaaaaaata gcagttgaag caccaagcgt
    23821 actaaaatca aatggaaaga tttttttaga aatcggattt cgccaaggtg aagcagtaaa
    23881 aaaaatattt cagcaagcat ttccagataa aaaagtggcg ataaaaaagg atctttttgg
    23941 caatgaacga atgatccaag tttatggttg aagttgtgga tgaaaaattt tttatttgtt
    24001 tttttattat aaaaaaacac ttatttgaca aggatgtaaa cgactttttg gtttatcaac
    24061 aagtttatcc actattgaca aatagattat ccacaaacag tggaaaactt gaggataaac
    24121 tcagacaaaa taagaatgta tgaaaaaggg gttgtggata aactgtggaa acgaaacgat
    24181 atgatgaaac agaattgcaa gaggcagccg aagcactgaa agaaggagaa cttgttgctt
    24241 ttcctaccga aacagtatac ggattgggcg ccaacgctct tttaccaaac gctgtcaaga
    24301 aagtgttttc tgtaaaaggg agaccgcaag ataatccatt aatcgtccat gtcgcctctt
    24361 ttgaacaagt aaaagagtat gtggacaact ttcatccggc agcagagaag attgtgaaga
    24421 acttctggcc tggaccatta actttgatat ttaagatcaa aaaagacact ttgccctcag
    24481 ttgtgacggg aggattatcc acagctgcat ttcgtatacc ggataacaaa aaaacactag
    24541 aagtaatcga actttccggt gttccgcttg tcggtccaag tgcaaatacg tcgggaaaac
    24601 caagtccaac gactgcagat catgtatatc atgatctaca aggaaaaatt accgggatta
    24661 ttgatgatgg agctacgcga attggtgtag aatccactgt tcttgattta agtgatccaa
    24721 cagccatgcc tatgatttta cgaccaggtg cagtaacgaa agaacaaatc gaagcagtca
    24781 tcgaatctcc tgttgctatt gatcagcatc ttgtaaaaga aaatgaaaca ccaaaagccc
    24841 ctgggatgaa atacaaacac tactcacccg atacacgtgt tctgatggtc agagatggcg
    24901 attggtcaac tgcagttcaa tgggcaaaaa ataagaagat ccgtgcaggt gtcatagcaa
    24961 gccccgaaat tgcggatcaa gtgcggacag atactgcagc tgtttatatg tataacgaca
    25021 actcagtaga agcggcggct aaaggattgt ttgcaggtct aagaggatta gatgaaccaa
    25081 cacttggatt agatttgatt tttgtacaag tgtatccaga aactggattg gggaatgctt
    25141 acatgaatcg cttgaaaaaa gcagcaggac aaaattattt tgaaaaatga tcaattggtt
    25201 attgtcgcat tcttttagta tgatacaatg ctatcaagta aatcttctat cagtgaacga
    25261 aaaactaagc gtaactaatc gtaatagaag agatacgaat atttggcaat ttgtttttga
    25321 tgggaaaaat aaaattgtag gaaaataaaa aggagctgtt gtttgtggta gattacaaaa
    25381 cgtttgaccc tgatctttgg gctgcgatcg ccaaagaaga agaaagacaa gaacataatt
    25441 tggagctgat tgcctctgaa aactttgtct ccgaagcagt gatggctgca caaggaagta
    25501 tcttgacaaa taaatacgca gaaggttatc cagggcatcg ctattatggt gggtgtgaat
    25561 ttgtcgatat cgttgaaaat ttagcgattg accgtgcaaa agaattattc ggagcgaaat
    25621 ttgcgaacgt ccagcctcac tccggctctc aagccaacac ggctgcttat ctcgctttgg
    25681 tagaaccagg ggacacgatc ttaggaatgg atctttccgc aggcggacat ctaacacatg
    25741 gatcaccagt caacttcagt ggcaaaacct atcactttgt tgcttacggt gttgatccga
    25801 caacagaagt tattgattat aatgtggtac gtattttagc tagaaaacat caaccaaaat
    25861 tgatcgtagc aggtgccagt gcttacggac gaacgatcga ctttgcgaaa ttcagagaaa
    25921 tcgcagatga agtaggcgca aaactgatgg tagatatggc acatatcgca ggattagtag
    25981 cagcaggact tcatcctaat ccagttcctt atgcagatat cacaacgact accactcata
    26041 aaacattgcg tggccctcga ggcggcatga ttttgacaaa cgatgaagca ttagcaaaaa
    26101 aaataaatag tgcggtattt cctggtattc aaggcggccc tctagagcat gtgattgcgg
    26161 gtaaagcagt agcattcaaa gaagcattag atcctgcatt taaagaatat agtgaacaaa
    26221 tcatcgccaa tgcaaaagca atggtcaaag ttttcaatca agcaattgga accagagtca
    26281 tttcaggggc gacagataat catctgatgt tgatcgatgt tcgcgagtta ggtataaatg
    26341 gaaaagaagc agagagcatt ttggacagtg tgaatatcac tgtaaataaa aactcgattc
    26401 cttttgaaac actaagtcca ttcaaaacaa gcggtattcg aatcggcacg ccagcaatca
    26461 ctactcgcgg gttcaaagaa gaagatgctg taaaagtggc tgaactagtt gtcaaagcat
    26521 tacaagcaaa agatgataac gctcaactag acgaagtcaa aacaggtgta cgcgaattaa
    26581 ctgaaaaatt tccgttgcat aaaaaataaa aatttaaatt ccattagtaa acagaaaagt
    26641 tcaatgttgg gcttttctgt ttattttttg ggaaaacgga ttctttgaca atatcggtga
    26701 tgctctctag tatatgaggt gtaattttag tcttcacact aaatctcagg gaggaaaagt
    26761 catgactgat cgtatctcgt tagaaaagga agcagtagca ttcagtgatg caaatgcgcc
    26821 tcatccgcgt atctatgaac tagcaccgga agaaggaaga gttttactag aagaagtaca
    26881 agaatcacct gtgaacaaat attccgtcga tattgaagac ttgatggtgg atactggcga
    26941 atggggaaaa ctcaatattc gtctcgtacg accagaaggg aatatggata aattaccagt
    27001 tattttttat attcatggag caggctgggt ttttggcagt gctcaaaccc atgataaatt
    27061 gatcagagaa cttgcggttc gtacgaattc cgtcgttgtc tttccagaat atagtcgatc
    27121 accagaagca aaatatccaa cagcaattga acaaaattat gctgtgttgc aacagctgaa
    27181 taaattagcc aagtcaaaaa atctggatct cgagaatcta atcgttgcag gagattcagt
    27241 aggtggtaac atggctacag tcatgacgat cttaacaaaa gaacgaaagg gcctcccaat
    27301 atccaagcaa ttgctgtatt atccagtcac aaacgctgat tttgatacag attcctatca
    27361 tgaattcgga gaaaactatt ttttgacaag agaaggaatg atgtggtttt gggaccaata
    27421 tacgacgaat gaagaagagc gtgctgaaat cacagcttcg cctttgagag caaatataaa
    27481 tgaactaaat gatcttcctt cagcaatgat tttaacggga gaagcggatg tattaagaga
    27541 tgaaggtgag gcttatgcgc gcaaacttcg tgatgcaggg gttcctgtta cacaagtacg
    27601 cttccaagga atcatccatg attttgtcat ggtaaatgct atggatcaga caaaggcaac
    27661 gcgtgcagca atggcattat ctacttcttg gatcaagaaa aaagaataag ctttgcttgt
    27721 ccgcaggaaa acttcttttc aaaaacggat tttcttagga aaaatggcga gtttgactag
    27781 tcaatcactt gattttgttt tacaattaaa aagaaacgac agaacaaagg agagcttaaa
    27841 aaatgggcaa atttcaagtg atcgatcatc cattgattca acacaaacta actattattc
    27901 gggacaaaaa ctgcggaaca aaggtttttc gtgaagtagt cgatgaaatc gctatgttga
    27961 tggcatatga agtatcacgg gatatgccat tggaagacat cgtgatcgaa acaccgatca
    28021 ctgaaacaac acaaaaaacg ttgtctggta aaaaagtagc gattattcca atcttgcgcg
    28081 caggtattgg aatggttgac ggtatcttgg aattgattcc agctgctaaa gtgggacata
    28141 tcggtcttta tcgagatgaa gaaacattgg aaccacatga atatttcgtc aaacttccag
    28201 aagacattga tgcacgtcag ttgtttgtag tagatccaat gttggcaaca ggcggatcag
    28261 caatcatggc aatcgatgca ttgaaagaac gtggcgcgtc gaacattaaa tttgtttgtt
    28321 tggtagcagc acctgaggga gtaaaagctt tgcaagaagc gcatcctgat attgacatct
    28381 atacagcttc tctagatgaa aaattgaatg aacatggtta tatcgttcct ggactagggg
    28441 atgcgggtga ccgtttgttt ggtacaaaat aagtaaatac gaaaaagggt gtgacacaac
    28501 ttttgtcaca tccttttttg gtcattttta acgtttgatg cagaacagct ttttcacagc
    28561 tttcgtttgc atataaaaaa accatcccaa aaatgcagag atggtcaaat tcaaatcttt
    28621 tttagttctt tgtagttaac gattactaca cccttacttt gcgtcatcaa gttcgcattt
    28681 tctgcagttt catcaatctc aacaacagcg gaatttttca attgctttga aatcgttcca
    28741 gtttgcgact tgccgtgaat tgtgaacatt acgtgagtat tgatcttgaa tttttcacca
    28801 atttccgatg gtacgatagt tgtatcaaat tttccaaaag ttgccatttt cataaaacct
    28861 gcctttcaca tcaattatac cacgttttat gaaaaatatc atgaaattaa actaattttc
    28921 catcggactc tttacaatca gccaaataga gtatataatt tcttttggat aaggccagct
    28981 tagctcagtt ggtagagcaa cgcactcgta acgcgtaggt cgtaggttcg atccctatag
    29041 ctggcattaa aagagaagac agatatatca aggattttta atccattgat acatctgtct
    29101 ttttgtttaa aggaaataaa gtatgctttc ttagcaatag agcatgtatt atttctataa
    29161 aaatttagga gaataaaacg actagcaata tagctgtgaa atcaaatatc acatgaactg
    29221 cccaacttgt aatgatcgag ttgcttttaa tggcagcttg gttgaataac aatcttgcca
    29281 ccccttgtat caaaaggatg tgtgctacag tgtgtaaaat atttccatta tcataagtac
    29341 tgtaatggat aaatccaaag atgattgctg acaagaaact agcgacagga atgctgaact
    29401 tactagaaaa aatagcgaga aaatacactg agaacaattc ttctccaagt atcatgatag
    29461 gcaaaataat aaataataac gggctgaaag cctcatttat tggattgcct gttaaacccc
    29521 atttcaaaat ttgttgcaaa aataccgaga ctgcggcact gattactaca ttgataaaaa
    29581 aatatttggc tatatttttg acaggagcga caggtttcga gaacattttt ttcgtatctt
    29641 ttttaccaaa aacaagtgta aatgctataa atccagtgat agttaaagaa aaaatgctaa
    29701 taatggatgg cgcaaatagc aaccctaaca aaccgagtac aacgacaata gtgcccaata
    29761 tccctttttt aagttctatt ttttttccta aaatgttatt catgataata actcctacta
    29821 ttcagttttt gaagatagag tcagtataca tgaagagtta aaataggcaa tgttttttta
    29881 tggatatttg tattgctaaa aatttatctt atatattcat tttgattata ctacttttat
    29941 ttgtaaaaat tttctagcaa aaccaagtgc ttgcaactga ttaagcgtac aattttttag
    30001 atgttccgag cgtacttcaa tcatttcaaa ggagttgcta cttaaatcga tattttttaa
    30061 atcagtatca aaaaagctag cattttctaa atcattagta gaaaacatta ttttagtgag
    30121 ggaacagtct acaaaatctg cgcttgataa gacagagtgc tcaaaggtac tttcttttat
    30181 gtttgaacca gataaattta catagtccat tttacaattc tcgaataacg tgttcccaat
    30241 ataactttcc atcaatttag tacctgttaa tttacaattg acaaatttca cgcgatgcaa
    30301 catgcttttt gtcaatatac agcctgaaaa atcacagttt tcgaatatac agtcggtaat
    30361 ctccattctt tgaaaatcat tggaagcaaa aaatgcatac ttgaaaatag atttgtaaat
    30421 aattggatgg cagattattt ggttttcgat gacctctttt tgtgaaagga tattatacag
    30481 ttcaaaatct tcgttttcat agatatgaaa aaaggatcct ttattcaagc ttgcttcatt
    30541 aactttagga aaaatcatat ttaattacct ccattttcat aaagtcatat taacaaaagc
    30601 taaaccaact tacattagca gaaaatgaga taggttttcg cctttttcga taacgatagt
    30661 gtcgctatct cttgaaacgt tcttagaatt gccctgagag acacaaatta ggcgtaattc
    30721 taataaaaat cttagaataa aaatttttac tgatttaatt tagaatgttt ttaaaataaa
    30781 aatcgttgcc ataacagtgt attgaaaggt tttaacaatc cagtaatgat ttaaaaaaat
    30841 ctagatgtag cgtatacttt gtttatagaa tgtagtggga agaaatatat ttttgggagg
    30901 aaatcgtgat gtctaaaagt gaagaaatag aaaacatggt actaaaatta tatgatctcg
    30961 ttttaaatcc agagatcaaa gaaaaggaac gtatactttt gatagacgca aagacaggct
    31021 tagaaaaagg tcagtattat cctaaagtca taaataattt ggaacgtagt ttacgtccgt
    31081 tagcaatcag gggagaattg tctaaaccag tatcaccgtt ttatatggag atatcaacaa
    31141 taggaaaatt tgaaaaagaa ttaggtcgag gaatggcttc ggcaccgatt acttttgggc
    31201 atttataaaa acgagttatt catctcaatg aattaaaaag tatagtcaat ctcataatgc
    31261 aggctaggtt catttatttg aacagagtct gtattttttt attctaaata aagaaacaga
    31321 tgtttcttta tattgtattt tatcctttaa ttaacacaaa aacagctagt ataaactaat
    31381 aatgttaatt aaaagtgtat tttatgaaac tatcgttatt tattaatgtt gcatttttgt
    31441 aagttaaaaa ttggaaatat agattgaaaa aatgaaag
//
LOCUS       DAFEML010000025        30976 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFEML010000025
VERSION     DAFEML010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.025"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            162..1103
                     /locus_tag="LP468_001356"
     CDS             162..1103
                     /locus_tag="LP468_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL2080900.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1172..1903
                     /locus_tag="LP468_001357"
     CDS             1172..1903
                     /locus_tag="LP468_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL2080901.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2047..4227
                     /locus_tag="LP468_001358"
     CDS             2047..4227
                     /locus_tag="LP468_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL2080902.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4247..4729
                     /locus_tag="LP468_001359"
     CDS             4247..4729
                     /locus_tag="LP468_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL2080903.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4745..5506
                     /locus_tag="LP468_001360"
     CDS             4745..5506
                     /locus_tag="LP468_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2080904.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5637..6971
                     /locus_tag="LP468_001361"
     CDS             5637..6971
                     /locus_tag="LP468_001361"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL2080905.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7278..7763
                     /locus_tag="LP468_001362"
     CDS             7278..7763
                     /locus_tag="LP468_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL2080906.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            7756..8439
                     /locus_tag="LP468_001363"
     CDS             7756..8439
                     /locus_tag="LP468_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL2080907.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8565..11210
                     /gene="polA"
                     /locus_tag="LP468_001364"
     CDS             8565..11210
                     /gene="polA"
                     /locus_tag="LP468_001364"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL2080908.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11255..12091
                     /gene="mutM"
                     /locus_tag="LP468_001365"
     CDS             11255..12091
                     /gene="mutM"
                     /locus_tag="LP468_001365"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL2080909.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12055..12684
                     /locus_tag="LP468_001366"
     CDS             12055..12684
                     /locus_tag="LP468_001366"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL2080910.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            12736..13068
                     /locus_tag="LP468_001367"
     CDS             12736..13068
                     /locus_tag="LP468_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2080911.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13380..13871
                     /gene="nrdR"
                     /locus_tag="LP468_001368"
     CDS             13380..13871
                     /gene="nrdR"
                     /locus_tag="LP468_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL2080912.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            13894..15267
                     /locus_tag="LP468_001369"
     CDS             13894..15267
                     /locus_tag="LP468_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2080913.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15267..16193
                     /gene="dnaI"
                     /locus_tag="LP468_001370"
     CDS             15267..16193
                     /gene="dnaI"
                     /locus_tag="LP468_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL2080914.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16322..16762
                     /locus_tag="LP468_001371"
     CDS             16322..16762
                     /locus_tag="LP468_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2080915.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            16906..17607
                     /locus_tag="LP468_001372"
     CDS             16906..17607
                     /locus_tag="LP468_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL2080916.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17604..18725
                     /locus_tag="LP468_001373"
     CDS             17604..18725
                     /locus_tag="LP468_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL2080917.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            18740..19972
                     /gene="pepT"
                     /locus_tag="LP468_001374"
     CDS             18740..19972
                     /gene="pepT"
                     /locus_tag="LP468_001374"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL2080918.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20104..21012
                     /locus_tag="LP468_001375"
     CDS             20104..21012
                     /locus_tag="LP468_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL2080919.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21047..21319
                     /locus_tag="LP468_001376"
     CDS             21047..21319
                     /locus_tag="LP468_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL2080920.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21330..22376
                     /locus_tag="LP468_001377"
     CDS             21330..22376
                     /locus_tag="LP468_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL2080921.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            22627..25236
                     /gene="clpB"
                     /locus_tag="LP468_001378"
     CDS             22627..25236
                     /gene="clpB"
                     /locus_tag="LP468_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL2080922.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25387..26073)
                     /locus_tag="LP468_001379"
     CDS             complement(25387..26073)
                     /locus_tag="LP468_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080923.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26051..26545)
                     /locus_tag="LP468_001380"
     CDS             complement(26051..26545)
                     /locus_tag="LP468_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2080924.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26565..27785)
                     /locus_tag="LP468_001381"
     CDS             complement(26565..27785)
                     /locus_tag="LP468_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2080925.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            27932..29767
                     /gene="lepA"
                     /locus_tag="LP468_001382"
     CDS             27932..29767
                     /gene="lepA"
                     /locus_tag="LP468_001382"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL2080926.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(29861..>30976)
                     /locus_tag="LP468_001383"
     CDS             complement(29861..>30976)
                     /locus_tag="LP468_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2080927.1"
                     /translation="FVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVLSDID
                     ETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLS
                     PALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEAR
                     PTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNG
                     TITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYI
                     DSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEIS
                     ERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10313 a         5547 c         6636 g         8480 t
ORIGIN      
        1 ttttctgtgc gaaacaggaa agcgaagtct ttttaattca aataataata ttatgtaaac
       61 aaaaaacttt ccatgcgtaa ttatacacaa gcaaataaat cgtcaaatgc gaacgccttc
      121 tttatactgt ttaggaacga aaagaaggaa ggaagaaata catggattat caagtactgc
      181 tttattacaa ttatacaaaa atcgaagaac cagaggaatt tgccaaaaat catttagcct
      241 tttgcaaatc tttggatctt aaaggtcgta ttctagtagc tgaagaagga ataaatggta
      301 ctgtgtctgg aaccgttgaa aacacgactg cctatatgaa agcaatgaaa gctgatcctc
      361 gatttgctga tacgatgttc aagatcgatc caagcgaagg acatgccttt aagaagatgt
      421 ttgtaagata ccgtccagag cttgtaagtt taaagctaga agaggacatt gatccaaacc
      481 aagtgacagg tgcctatctt tcaccgcaag aatttaaaga agctatttta gatgaacaga
      541 cagtggtgat tgatgcacgg aatgattatg aatatgactt gggacatttt cgaggggctg
      601 tacgcccaga tatacgcagt tttcgagagc ttccagactg gatccgcgag cacaaagaag
      661 aatttatgga aaaacgggta gtgacctact gtactggtgg cattcgttgc gagaagtttt
      721 ctggttggct tgtccgtgaa ggattcaaag atgtcggaca gctgcatggc ggtattgcta
      781 cttatggtaa ggatcctgaa gtccaaggag aattatggga cggcaagatg tatgtgtttg
      841 atgaacggat cgctgtcgat atcaaccaag tagataaaca aatcgtcggt cgcgactggt
      901 ttgacggaac accatgtgaa cgatatatca attgtagcaa tcctgagtgc aatcgtcaga
      961 ttcttgcttc cattgaaaat gaagaaaaac atttaggagc atgtagcata gagtgtgcga
     1021 aacatccgcg caatcgctat gttcaagacc atggaatctc tccagaagaa gcagaactgc
     1081 ggtttacagc tttaattaaa tagaaaacaa tagttttgat tgtcgaccat ttccaatatg
     1141 cgctatacta gcgttgagga tggtgatcca catgaaatca ttgatttatg ctattgggga
     1201 tgtccatggc aaacatgagc tttttgaaaa acttattcac tattatgatc caaagatcca
     1261 tcagcttgtt ttattagggg atctcaatga tcgaggtcct cgtacaaaag aatgtttttt
     1321 attaggaaag caattagtcg aagaaacagg agccatttac ctccggggaa accatgaaga
     1381 atattttttg caatttctgc aatcaccgga ggactggtat gcgccttata tgagaaatgg
     1441 tggaaaagaa acgtttgaaa gcctgattca cccaggggca tcggaggaat actccccaac
     1501 tgaaatctcg atgatgatcc aatcgagata ttcagaactg attaaatttt tagtccagcg
     1561 ccccttgtat tatgaatggg aaaattatct ttttgtccat gccggtgtgg atttgacaaa
     1621 gaaagactgg cgtaagacaa gtctaagaga ctttatttgg ataagggaac catttcatga
     1681 agggaaaaac aatacaggta agacaattgt atttggacat acgattacac caatgctcca
     1741 tggagatatg cagacaacag acctctggat tcaggatcat aaaatcggaa tggacggtgg
     1801 ggctgtattc ggagggtcat tgcatggggt tgtttttgac aaggaaggta ttcttcaaga
     1861 tattgaatat cagaacaacg aaggaccttg gcatggaatc tgactaatgg aaagaatgaa
     1921 ggagctgtga ctttgttgcg gctcttttta tttttataga gaatattgtt tctttcagta
     1981 gtttaaccca ggataaaaag tatgatagaa taaagaagca atttttagca gaaaagaggc
     2041 attttaatga cggaaaattt gaaccagacg atcattcagc ttgtacaaaa agaactttca
     2101 gactatcgtc ctaagcagtt gactactgta cttaatttgt taaatgaagg aaacactgtt
     2161 ccttttatcg cgcgttaccg aaaagaaatg actggaagtc ttgatgaagt ccagattcgt
     2221 gaaatcgaag agcggtatgc ctatcttgaa aacttagaaa aacgtaaaac tgaagtgatt
     2281 cggctaatcg atgaacaagg gaaactgact cccgagttag aagcagaaat cacccaagcc
     2341 gtgaaaatgc aacaagtgga agatttgtat cgtccataca aacaaaaacg acggacaaaa
     2401 gcaacgattg ctaaagaaaa aggacttgaa ccactcgcga agtggctgat gcagcttaca
     2461 gatggagagg tgcaatctga agcagaaaaa tatattgaca aagaaaaaga agtctcttct
     2521 gccgaagaag cgttgcacgg tgctcatgag attattgctg aacaagtcag cgataatgca
     2581 aaatttcgga cttggattcg gtcttatacg tataacaaag gtatgtatgt cagcaatgtc
     2641 aaggatgagc aagcagatga aaaaggcgta tatgaaatgt attatgactt tgcagaaccc
     2701 gtccataaaa tggtttctca tcgaatatta gctactaatc gtggagaaaa agaagatatt
     2761 ctgaaagtat tctttcaagt agatgaagca gcaattttag cttacttgga tcgccaaata
     2821 gtcaaaaatc ctgcctctcc ttcttcttca ttcgtcagag aagcctatca ggatagttat
     2881 aaacgcttta ttcagccagc aatcgagcga gaactgcgca atgaattgac tgaaaaggca
     2941 gatgagcaag caatcgctat tttcggcgaa aacctccgta atcttttgtt gcaaccgcca
     3001 ctaaaaggta aagttgtcct gggatttgat ccggcttatc gtactggatg taaactagca
     3061 gtcgtagatg cgacagggaa agttttagca atcgaagtta tttatcctca taaacctgca
     3121 gcgcaagcaa aaagagaagc tgctggacca gcttttatcc aattaattaa taaatatcaa
     3181 gtagatatgg tagctatcgg aaatggtaca gccagtcggg aatctgaact ttttgtggct
     3241 gagcagttga aatccgccga ccataaaacc tattacgcta tcgtcaacga agcaggcgct
     3301 tctgtttact ccgctagcga aattgcacga aaagaatttc cgcatctaca agttgaagaa
     3361 agaagtgctg tttctattgc ccgtcgcctg caagatcctt tagctgaatt agtcaaaatc
     3421 gatcctaaag ctgtcggagt aggccagtac caacatgacg tttctcaaaa acgtttggct
     3481 gaacaattgg attttgttgt ggaaacagcg gttaaccaag taggtgtgga tgtgaataca
     3541 gcaagcccgc agctcttgca gcatatatca ggattgaata aaacaactgc ccaaaacatt
     3601 gtcatttatc gtgaagaaaa cggagaattc accgcacgaa ctcaattgaa aaaagtgcca
     3661 cgcttaggac caaaagcata tgaacaagca atcggattct tgcgagtccc tggtgggaaa
     3721 aacattttgg acaacacagg tatccatccc gaaagttatt ctattgcaaa agaaatatta
     3781 acttcagtcc aactttcaga aaaagagctt ggtacagaag aagcagtaga aaaattgaca
     3841 cgattatccg tagagaaact ggctgaaagc ctatcagtcg gagaagaaac gttagccgat
     3901 attttagctg ggctgacaca acctggacga gatatgcgtg atgagatgcc agcgccctta
     3961 ttacgtacag atgtattgag tatggaagac ttgaaaccag ggatggaatt gactggaacg
     4021 gtccgtaatg tcattgactt cggcgcattt gttgatatcg gtgtgaagca agacggactt
     4081 gtccatatat cgaaactcag caaaaaattc gtcaagcatc ctacagatgt cgtgtcagta
     4141 ggagatatcg taacagtttg gatagaacaa gtcgatacga aaaaaggcag aatcagtttg
     4201 acgatgcttt ccccttatga agagtaacaa tgaggagtaa caaaaattga cacaagaaga
     4261 actgcagcag ttagtagaag agatatcatt aaaaagcttc cagcttcctt tcaagcacca
     4321 agcaatgttc aatccacgct tacgtacaac tggcgggcgc tatcatttaa acgatcatca
     4381 tttagatttt aatgcgaagc tatttgaaga gtcagacgaa gagacgattg caggaatcat
     4441 caaacatgaa ctttgccatt atcatcttca tctagctgga agagggtatc agcataaaga
     4501 tatggatttc aagtatcttt tgaaaaaaac aggagggttg cgctatgcac cagccttgac
     4561 gaagaaacag ataaagatgg agtattatcg atgccaagat tgttctgcca cgatctgccg
     4621 caagagaaga atcgatgtac gcaaatatcg ttgtggaaga tgtcatggag aaatcaaatg
     4681 gattgagaca aaaagagaag actttaatga agcacaaaaa atcagatgaa aggatagaag
     4741 gcctttggaa aaaagtgagc agaggaatct aaaagactgg aatcagctat taaatttttt
     4801 agccgcacct gaagagggaa attttgagga actgacggca cctacactta ttttagctgg
     4861 aaactgtctt cctatcttag ctgataaagc agcacaaatg tatttaaatg gccaagtaga
     4921 tcaattgttt ttggtcggag gggtggggca tgcgactaga atcctttatg agaattttga
     4981 aaagcaagga tttcattttg aagatggcat gagtgaaagt gaaatctgtc gtcagtatct
     5041 aaaagaagtc tatgatttgc ccgataaggc ttttctgata gaatcgaagt ctacaaattc
     5101 tggagagaac gccacttttt cactggagat tcttcattcc ttaggagctg taccagaaaa
     5161 aatcttattg atgaatgatc cgacactgca acgcaggact cgagcaactt ttgagaaagt
     5221 atggcaaaat gaacaaacta ttttcgcgaa tgctgtgcca tttgtgccgg aaatccttca
     5281 cttttctgaa gagatcatct ttacagcaaa agaactgaat catcaatggc ctaaggaata
     5341 tttccatgcg ctagtattag gagaaatgga acgtctccat gacgatgaga acggctatgg
     5401 tccgaaagga aaagatttta ttcctcacat tgatatatca gaggaagttt ggtcttctta
     5461 caccagaatt aaagagtcaa taaaaacgga tttttctcgt acttgaccat tttagcaagc
     5521 gaatcctcct ttccaaataa atttggttga aattttcaat cgtttataag ataatgagga
     5581 gcgtgttgaa tgtaatagct aaaagaatgg acgctagata agagaagagg attcaaatgg
     5641 aaaatcaaaa taaattgtat cattttgttg gtatcaaagg ttcaggaatg agctccttgg
     5701 ctcttgtttt acatgaacaa ggtctaaatg tccaaggatc agacattgaa aaatatttct
     5761 ttacacaaag agatttagaa aaagcaaata tcacgattct gccatttaac gcagataatg
     5821 taaaaccagg gatgacgatc attgcaggaa atgcatttcc tgattcacat gaagaaatcc
     5881 agcgagcaaa agaattaggt ttggaagtga ttcgctatca cgactttatt ggtcatttta
     5941 tccaaaatta tacgagtatc gctgtaacag gctctcacgg aaaaacaagt acgactggac
     6001 tgctctctca tgtattgagt ggtgtccgtc caacaagtta tctaattgga gatggaacag
     6061 gacatggtga tccgcaagcg gaattctttt catttgaggc ctgtgaatat cgccgtcatt
     6121 tccttgccta ttcaccagac tatgcaatca tgaccaatat cgattttgat catccggatt
     6181 attatacaag tatcgacgat gtatttacag ctttccaaac aatggctgga caagtgaaaa
     6241 aagctatttt tgcgtatggt gacgatgctt atttacgcaa attaaaagca aatgtgccga
     6301 tttattatta tggtgtcaca gaaaacgatg atatccaagc acgaaacatc gaacgcacaa
     6361 cttctggttc tgcttttgat gtctatcatg gggatgaatt tgttgggcac ttcactgtac
     6421 cagcattcgg taaacacaat atcttaaatg ctttaggtgt tattgcagta gcttatttcg
     6481 aaaaactgga tctgaaagaa gttgcagaag aaatgctgac tttcccagga gtaaaacgtc
     6541 gattcagtga aaagatcgta gcagacatga ccgtagtcga tgattatgcg catcaccctg
     6601 cagagatcaa agcaacgatt gatggcgcac gccaaaaata tccagataaa gaaataattg
     6661 cagttttcca accccatacg tttacgcgta cgattgcatt gatggatgaa tttgcagaag
     6721 cacttgattt agctgataaa gtttacttat gcgatatttt tggttcggct cgggaagaac
     6781 aaggaaacgt taagattgaa gaccttggag cgaaaatcaa aaaaggtgga gaagtcatca
     6841 aagaaaataa tgtatctcca ttgttagatt atcatgatgc agtagtaatc ttcatgggtg
     6901 ctggagatgt tcaaaaattt gaacaagcgt atgaaaaact tttaagcagc acgacgaaaa
     6961 atgtactgta atacaattac tgcagtgtcc ttataaaaat agaaagaggg ggagtggcaa
     7021 aaatcttgcc aagccccctt ttttgcaact tatgataaac ggtgttcaaa agcttgcatc
     7081 tgcggtaata agcccaatca aatcaaaaac atgagaagct gttttttctt ggctgttctt
     7141 attatttgat gcaggacagc tttttcacga cctctgtaaa ctataggaat ctgttaaatc
     7201 aagggagcag aacttgcctt ttacgctact tttggtacaa taatgtatga ttaaaaataa
     7261 actggagggt ttctatcttg aacataggta agccgagaaa actaggaaaa acaataaatg
     7321 aaatcgagga aggcgactcg ttatccttaa cagaatctat tgaagataac cagcttttgc
     7381 tgtatttggg attgacgaat gatgcaaatc ctttgtatat ccaacatgac tttgcacaaa
     7441 aaacagaata tcaacagcca atcgttccat cagtgatgct gatggggatc atcacaagtg
     7501 caatttcaaa gcatcttcct ggaccaggat cacatgttgt caatttttct gtcaatttta
     7561 ttgaaccggt tttccattat gaaacactga cttttcagtt tgaggtcata aaagtagata
     7621 agatgaagga tgtggtgacg atttctgtag aagcggagaa tacgaacgaa gatcgtgtgt
     7681 tggatgctgt cgttatggtc caaccgccac aagttcctga attggaaata gcaatcgaaa
     7741 gtgaaggtga attgaatgaa taatccaagt acatcaatgt caggtatcaa tcgtttttat
     7801 gcaaaagttt atggattttt aggtatggga cttgccctta gtgcagtcac ttcttacttg
     7861 gctctttggg tatttccttt gcaattagca acttttatca ataattttcc actaggcttt
     7921 gtgggtctgt ggatcgttga actgatttta gtaatggttc taggcgtaaa agcacaaaag
     7981 aatccgagct tagcaatcgg tggatttatt gcctactctc ttttgaatgg cataacatta
     8041 gcggttactc ttgcatacta cgatattgga acagtaacgc aagctttctt gacagctact
     8101 ttgatgttca tggggatgtc tgttgtcgga gtaacaacaa aaagagatct tagcggggtt
     8161 ggaagagcag gacaggcagc tttaatcgga gtgatcattg cactagtctt gaacatcttc
     8221 attttgagaa gtagcgtagt tgagctgttc atctccctac tgttagtcgt catctttgca
     8281 gggattacag cttatgataa ccaaagcatc cgtaatatct atgtccagac aaacggaaca
     8341 gcacatagtg gaattgctgt attcatggca ttgaagctgt atttggactt tatcaacttg
     8401 ttcttggcgt ttctgagaat ctttggacgg aacaactaaa aaagaaaaaa attcatcagt
     8461 tggggctata ccgaattatt tggtatggtc ccgctttttc ttttcgcatt ccgcaggatt
     8521 ctttgttaga atgaataaga actttacagt aaggagttaa gaagatgaca aaaaataaat
     8581 tattactcgt tgatgggaac agtgtggctt ttcgcgcatt ctttgcgctt cacaattctc
     8641 ttgaacgttt caaaaataga aacggtcttc atacaaatgc aatctatgca ttcaatacga
     8701 tgtttgaaaa tgttatgcaa aaagagcaac cgactcatgt tctggttgcg ttcgatgcag
     8761 gaaaaacgac ttttcggaca gaaatgtatg cggagtacaa aggtggaaga tccaaaacac
     8821 ctggcgaatt caaagaacaa atgccatata tacgtgattt gttgacagga ctaggggtac
     8881 agtattacga attgcccaat tatgaagcag atgatattat cggtactttg gcagaaaaag
     8941 tagacaaaga tcaatttgat gtcgtcgtgc tttcaggtga tcgggatttg actcaattag
     9001 ctagtaaaga agtaaaagtg gatatcactg taaaaggtgt cagcgatatc gaaagctata
     9061 caccagaaca tgtagcggaa aaatatgatg ggttgacgcc aaaacagatt attgacatga
     9121 agggactagc cggagatgcc tctgacaata tccccggtgt gactaaaatc ggtgaaaaaa
     9181 cagctatcaa gctattgaaa caatatggct cagtcgaagg aatttatgaa catatcgatg
     9241 aaatgaagca aagcaaaatg aaagaaaatc tgataaatga caaagagcag gctttcttat
     9301 cgaaaaaatt ggcgaccatc aatacttcag cgcctgtgga tgtctctatc gactcattga
     9361 agtatgaagg gaaaaatctc gataaactcg ttccgtttta taaagaaatg gatttcaatc
     9421 agttcctttc taaattgaat atcgtagaag aagaagtaaa aatggatgat attttgtttg
     9481 aagtcgttca tgaattcaaa gaggaaatgt ttactacgga tatggcgttg tacgtggaaa
     9541 tgatgggcga caattatcat acagaggaaa tcgtcggagt agcgtggggg acagaaaaga
     9601 aaatttatgt cacgaacgat ctatctgtat tcgaaaaccg agcgttccat tcttggatca
     9661 ctgatccgac tcggctgaaa aaagtatatg atgcgaaacg aacttatgtt gctttaaacc
     9721 gctatactgg aaaaacgaaa ggaatcgatt ttgatgtctt gctaggtgca taccttctcg
     9781 atacgaatga aaaaagcaca gatatcgaag gaatagctgc tcattacgga tacaacgata
     9841 tccaatcaga tgaagctgta tacggcaaag gggcgaaaaa aggtttacca gaagaagagg
     9901 aactcttttt tgctcattta gcgcgaaaag tagctgcaat caatgcgttg acaccaaaat
     9961 tgagccaaga actggcagat aaaaaccaag aagatctttt ccggaaaatg gaactgccat
    10021 tgtctatcat tttggcagag atggaaataa gcgggatcaa agtagatgcg actcgcttac
    10081 aagaaatgaa gggcgagttc tctgctcgct taagagagat cgaacaaaaa atctacgaag
    10141 aagccggcga agaattcaat ttgaattcac caaagcaatt aggagtgatc ttatttgaaa
    10201 aaatgggatt acccgttatc aaaaaaacaa aaactggata ttccacagcc gtagatgtac
    10261 tggaacagct tcgtgaacaa gcaccaatcg tagaggatat cctcacctat cgtcaaattg
    10321 caaaaattca atctacctat gtcgagggac tgctgaaagt gatccaatca gatggaaaag
    10381 tgcatacccg ttatgtccag acattgaccc aaacaggacg attaagctct gttgatccta
    10441 atttgcagaa catcccgatt cgattagatg aagggagaaa gatacgtcag gcatttgttc
    10501 ctagagaaaa agactggctg atttattctt ctgactattc acaaatcgag ttacgcgtac
    10561 ttgcgcatat ctcaaatgat gaacatttga aagctgcctt cctagaaggt caagatatcc
    10621 atgccagcac agcgatgcgt gtatttggaa tcgaaaaggc agaggatgtc acaccaaata
    10681 tgcgtaggca ggcaaaagca gtgaattttg gtatcgtgta tggcatctct gattacggac
    10741 tttcacaaaa tctaggaatc agccgaaaag cagcacagca atacatcgat acgtactttg
    10801 aaaaataccc aggtgtcaaa gaatatatgg aaagaatcgt acgcgaagca aaagaccaag
    10861 gctacgtcga aacgctgtat caccgccgtc gatatctgcc agacatcaat tcaagaaatt
    10921 acaatatccg ttcttttgcg gaacgaacag ctatcaatac accaatccaa ggaagtgctg
    10981 ctgatatttt gaaaatcgcg atgatcgaat tggataaacg attaaaagaa acaggtcttc
    11041 aagctacgat gctgttacaa gttcatgatg aacttgtctt cgaggtaccg gaaaaagaac
    11101 ttgaatcatt agataaattg gtgaaggaag ttatggaaca agctgtttct cttcatgtac
    11161 cactgatcac tgacagcagt tggggaaaaa cgtggtacga agcaaaataa acattgttta
    11221 agacagagca atataatgaa ggtgaaaaga aaaaatgcca gaattaccag aagtagaaac
    11281 cgttcgtaaa ggattggaac ggttagtagt aggaaaaacg attcaaaaag ttcaggtctt
    11341 gtggcccaag atcatcgagc aaccagagac acccatcttt gaggcttctc ttgttggcga
    11401 aaccatccaa tccattggac gtagagggaa gtttttaatt tttcatctcg atcattgtga
    11461 actgatctca cacttgcgaa tggaaggaaa atatcaattt acgaaagaaa atacaccaat
    11521 cgataaacat acgcatgtac ttttcttttt tgaggatgga agccaacttc gctacaacga
    11581 tgtacgaaaa tttggtcgta tgacaatcgt cgaaaaagga gcaagtgcaa cttaccgagg
    11641 aatcatgaaa ttgggacctg agcctttgcc agatagcttc ttattagcag atttcgcaaa
    11701 tggactgaaa aagtcccaca aagcaatcaa gccattgctg ctagaccaac gtctagtgac
    11761 tggtctaggt aatatttatg tagatgaagc attatgggaa gcgaagatcc atccagaaca
    11821 accggcgaac acactgcgcc ccaaagaggt agaacaatta cgtctatcga tcattgatgt
    11881 tttggatcgt gcaatagaag ccggaggtac cacgattcgc agttatttga atgcattagg
    11941 agaatcaggc ggatttcaag tagcactgca tgtctatcag caaactggca aaccatgtat
    12001 acgttgtgga acgccgatcg tgaaaacaaa agtggcacaa agggggacgc actattgtcc
    12061 gaattgtcaa aggctaaaaa tcgcaaagta ggatttgttt taggtttgac gggtggaata
    12121 gctaccggta aaagtacggc agccaaagtc tttcagtctc atggatttcc tttgatcgat
    12181 ggcgatgtga ttgccagaga aactgttgag cctggaacgc ttgctctgag gaaaattgta
    12241 tcagtgtttg gccaagaggt attgcagcct gatgggcaac tagatcgagg gaaacttggg
    12301 atgattgttt ttccatcaaa ggaaaaacgg caaaaacttg atcagctatt agatccgttt
    12361 atccgaaaag cgataaaaga tcaaatcgcc tctctaagtt ccaatcatcc tttagtaatt
    12421 gtagatatcc cattgctcta cgaaggtcat tatgaccact atatggatgc agtagctgtc
    12481 gtttatacta cgccagaaac tcagcttcag cgtttgatga aacgtaatca actgacgcta
    12541 gaacaagcgc agcagagaat tagtagtcaa cttccaatcg aagaaaaaaa gcagcgtgcg
    12601 gatattttgt tcgacaacaa tggaacaaaa gaaaaacttg tgggacaaat cgaaaattgg
    12661 ctttttgcta atcgctttct ttgagtatct gtgtcaattt tgctatcctg agtatataga
    12721 aagtgaggga tagcgatggg atcattaaaa aatcaaaagg ataaagtcgt aggtaacgca
    12781 aaagaaaaaa tcggcgagat gctcaataaa gaaaatctaa tcgatgaagg tcgtacgcaa
    12841 tcagaaacag cagaagaaaa agaaaagcag taccaagcaa gaatcgatga aatagaagac
    12901 cagcaggcag aagaagaagc gaagcggcaa gatttgactc aagaacgaaa aaatccgaca
    12961 cctgatcgta gtaaaacacc gctcccagaa agtgaccaca tttccgatga gcaaaaaatc
    13021 gaggaacagc gaatgaaaca ctatacagga atcgaagaga agttataaaa tagtaaaaaa
    13081 tcgagatgtg acttgaagca gatgagaagg tgttcatctg cttcaagttt tttgtgctag
    13141 atgactaaat cagcttttgt gtaagttatt tctcagtaat caaggtgatc agtattggaa
    13201 aattgaaatt tagtaaggac aggggacaca attacgcatg aaagtagaaa aaattgttct
    13261 tatatccgtg ttttttgggt aggacagtcg cgtttgtgat ttgtttcgtg ttataataca
    13321 actagttgta aagaaagaca catcctttat ataaaatgcg atgcaagagg tgagacaaaa
    13381 tgagatgtcc cagatgtcaa cataataatt cacgagtaat cgacagccgt caagcagatg
    13441 atggacgtgc gatccgtcgc cgtcgcgaat gtgagaattg ttcgttccga ttcactacat
    13501 ttgaacgaat tgaagctgct ccgttattag taatcaagaa aaacggggaa cgcgaagagt
    13561 tcaatcgcga taaaatttta agaggactca tccgttcagc agaaaaaaga cctgtagcta
    13621 tggaacaaat ggaacaaatc gtcaaccatg tcgaaaaccg cgtacgcagt ctcggagaaa
    13681 acgaagtatc gacgaatcta attggtgaat atgtgatgga agatttagtt gatttagacg
    13741 aaatcgctta tattcgtttt gcaagtgttt atcgccagtt caaagatatg tctgttttct
    13801 taaaagagtt gcaagatatc gtggataaag caaaagaaaa taataaagag aataataaag
    13861 aaaacaatta agaaacaaaa aggaggcatt tccttggaaa atgcttggaa agagcttcaa
    13921 ccaaaaaata tttaccaagg aagaaaagcg gctccgctga gagaagacag caagaacgcc
    13981 ttgctgtatc tttatcagcc actaatcggc ggagaagcct tgagtatcta tttcaccctg
    14041 ttatcagaaa tctctcaaga atctggcaaa ggtcctgaag ggatgcatgc agatctgctt
    14101 agtagtctag gctgcggtat cccgcaattt tatgatgcaa gaaaaaagct agaaggaatc
    14161 ggcttactgg atgtttattt taaagaagat agtgatctgg gacctcgttt tatttatgag
    14221 ctgttagaac cactcattcc taaagcattt ttcaaagact ctgttctggc ttttcttctt
    14281 ctggaaaaag ttggtgaacg acgattccag aagcttaccc aattctttga acctaaaagg
    14341 catacagcag agggatatca aaaaatcaca aaaaaatttt tagatgttta tcgcttcaat
    14401 gaagcagtgt acgctgctaa tcaagaaaac atcgaatcgc tgaataaatc ttttgaagaa
    14461 tctgaatcag tagcattact tgaagcagat tcgacattcg attggcagtt tttgaatgat
    14521 tggctggcaa aaaaacatat tgcaagtctt gatgatccaa tcatcaaaca agtcgacatg
    14581 tatcatcagc tttacggttt cgatgaattg acacttggcg aactgatcag tcaatcttat
    14641 gactttagtg aacaaaaagt atctgaaaaa gaactgcaaa aagccatttt ggcaatgcag
    14701 agacgtccgg tgaagcaaac aaaagaaaca gttgcggttt ctgaaaacag taatgaaccc
    14761 tcgtcaaacg aacatttgac aaacgcagcg cttcagctga taaaagaagc acagagcatt
    14821 ccaccgatga aatatctgga agcaatcaag tcagaaaaag gcggatatgt ttctaaacaa
    14881 gaaaactggt tactgcaaga tcttgtttct caatcaggtc tttccagtag cgtgatcaat
    14941 gttttgctga attatgtact agtgatcaag aataatgcta gcttaaatgc cagttatgta
    15001 aatacagtgg caaatgaatg ggcacaaaag aaaatcgcca cagcagaaga agcgatccag
    15061 cacattcggc aaataagtaa tcaagcaaaa caatcaaaac aaaagaagca aacaaattat
    15121 caaactggca agcgaaatgt tcgacgggaa aagcttcctg attgggtcaa ccagccaaaa
    15181 gatgaaaaac agatcagcag cgagaaaaaa gcagagattg accgccgttt taaagaatac
    15241 ctggcaaaaa aggagggtga tatctagtgg aagacgtagg caaagaattg aagaggatca
    15301 tcagcaaacg caattatcaa gaaaagtatg ctgaaatgat cgctgaagtc ttaaatgatg
    15361 cggatgttca agcttttcta agcgcacacc aagaagaatt gacacaagcg gatattgaaa
    15421 aaagttacgc taaattgtat gaattcgtgc aagaaaagcg taaatatcaa aaaaacgatc
    15481 caacgatgat cgctcccggc tatgagccga agctgacgtt gaattttcat tatgtggatg
    15541 tcacttatgt accaacggaa gcattgttag cacggcaaag acaagaagaa atcagaagcc
    15601 gagtaaaagc aatggatatg ccaaaagata ttcaatcggc ttcttttgaa aactttgaac
    15661 gtacagatgg acgaggatat gcgagcttag aagccctaga ttttgtagag aaatatactg
    15721 ctgatccaaa agggtatcat aaaggactgt atctagtagg aagttttggt attggaaaaa
    15781 catatttatt aggagcaaca gcgagagaat tagcgattgc tggattcacc acgacgctag
    15841 tccattttcc gacatttgcc gttgagatga aacaggcaat cggaaaagat caagtggcag
    15901 aaaagttaga tgcagtgaaa cgttcaccta ttttgatgat cgatgacatt ggtgcagatg
    15961 cgatgagtag ttggatacga gacgaagtat tcggtgttat ccttcaatat cggatgcagg
    16021 aacagttacc aaccttcttc tcatcgaatt ttacaatgga tgaattggaa cagcatttgt
    16081 ccgtcactca acgtggagat gaagagccgc taaaagcgaa acggataatg gaacgcatac
    16141 gttatttgac aaaagaaatc gaaatgactg gtcgcaaccg acgcaatggt tgaacagttg
    16201 acaagtccaa ctgacatttg acctagtagt aaaagcaggt cagcgaatca ttatatggac
    16261 agaaatgacc ggagacaatc accgcaacaa gtaatgcaga aacttaaacg gaggattttt
    16321 tatgagggct attttttcta gtatatctgt agttggtcta ttttttcttt tagcaggctg
    16381 cggtagcgca gatagcaaca caggttctgt tgattcgatt gatgcgggtc aaacagtaaa
    16441 aacaagcagt acgaaaacgg agagacaaag catatttgtc ggaacgattg aaagtattac
    16501 tcaagtagaa gcagaagaag aaacgcttca gttgaaactc gtcgatgtca tggccaaaga
    16561 agatccagcg aatatgggaa cgtcattcag caatgacgga gtgatcttaa atgctactgc
    16621 tgaaaaaata agcgtggaca taaatgaatt gaaaatcggt gacaaagtcc aatttacatt
    16681 agttgagatg ccgatcatga cgatgtctat cccaccgcaa gttcctggag attcgattat
    16741 tgatgtttca ttgaacaaat aaccaataac attttttcaa aaataagaaa atgttgtttt
    16801 atagaacgaa aaggtatatt ttttaaggag atatgggaat ttttttattc ctagtctcct
    16861 tattttattt ggaaaatgct ataattatct agaaggagtg aagctatgaa ccatttagat
    16921 ttatctcagc gcttagccgc agtgggtgac tttgtccctg aatccgctcg tttagcagac
    16981 attggatcag atcacgctta cttacccgtt gcattgatat taagaggaaa aatcgaatat
    17041 gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag cacgtaagca agtcaaaaaa
    17101 gatggattag aagaccgtat caccgtacgc cttgcaaatg gtctagatgc tatccagcca
    17161 caagatggta ttacagctgt cacgattgcg ggtatgggag gttcactgat ccgagatatc
    17221 ctagaagctg gcaagttgaa tcaacgctta agcggacaag aacgtttgat ccttcagcca
    17281 aacatcggag agcgtacatt acgatcttgg ctgcaagaaa atcagtataa aatccaatca
    17341 gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca ttgtagccga aaaagaacaa
    17401 aaaccagtta cttacaatga aatggagctg atgttcgggc catttctgct tgaagagaaa
    17461 agtgagatct tcaaatcaaa atggacaaga gagcttcaac aaagaaaagc tatccgtgaa
    17521 cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac aaatcgagca ggaaatccaa
    17581 atgattgagg aggttttaaa gccatgacaa tcagcggacg cactttcatc caaaagtttg
    17641 aaagctattg tcctcagtgg ctagctgaag aaggagaccc agtcggactg catatcggaa
    17701 cattggataa gccaatccaa cgagtaatga tgacattaga cgttcgtcca gaagtggtcg
    17761 aagaagcaat caagaaaaaa atcgatttgc tgattgctaa acatcctcca atctttcgtc
    17821 ctgtaaaacg gctggttact gatcagccac aagaaaaaat gtatgcagat ttgttgaaac
    17881 atgatattgc cgtctatgca gcacacacga acatggatat tatttgggat ggactgaatg
    17941 actggttttg tgaacttctc ggtattgaag tggagagtta tttagtaaag actcatgaga
    18001 ttcattataa aaaactggcc gtttatgtac ctgtggatca tgcacagaaa atgcgtgaag
    18061 tattagctgc agctggtgct ggtacacaag gtgattatac cggtacaagt tttacctcga
    18121 ttggacacgg tcgatttact ccggaagctg gtgcacaacc agcgattggg aaagtaggga
    18181 agacagaaca agttcaagag gcaaaagttg aggttatttt gccggaaact atcgaaaaac
    18241 aagtgattca agccatgcgg tcagctcatc cttatgagga acctgcttat gatcttttcg
    18301 ctatagatga accagtcgaa atgtttgggt taggacgagt aggggaattg ccgcaagaaa
    18361 tttctataga ggcatttgta gaacaagtaa aagaagcgtt ccaactagat ggactgagaa
    18421 tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat tgcgatttgc ggtggaagcg
    18481 gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga tgtctatatc acgggagata
    18541 tctattatca tacggctcat gatatgcaaa gcgctgggtt gattgcaatt gatcccggtc
    18601 attatattga atcgttatgc aagcaacgat ttatcgagaa atttgaatct tggaaacaag
    18661 aagaaaattg ggatattaac tttttcgttt ctgaaacaaa tacaaaccca tttcaattta
    18721 attaaaagga gagaatacta tgtacgaaaa tcttttgcca cgttttttac gatatgtcaa
    18781 aacagaaaca cgctccgatg caacaagcaa aacgactcca tcgactcaga cacaagttgc
    18841 ttttgcgcaa gaattgaaaa aagaattaga agagttaggc ttagctgatg ttttctataa
    18901 tgaagataac ggattcgtta tgggaacatt accaagcaat gttgatcatg aagtgcgttc
    18961 cattggattt atttcccaca tggatacagc agattttaat gcagtaggag tcaatccaca
    19021 aatcattgaa aactatgatg gcgagtctac gatcgtacta gatgcggaag aacgctatac
    19081 attgaataca aaagattttc caaatttgaa aaattatgaa ggccacacat tgatcacaac
    19141 agatggcagt acattactgg gagcagatga caaatcaggg attgcggaaa tcatgactgc
    19201 aatggagatc ttgatcaata atccttctat ccctcacggt accatcaaag tggcttttgg
    19261 tcctgatgaa gaaatcggtg tcggagcgga taaattcgat gttgagcaat tcgatgtaga
    19321 ttttgcttat acagtcgatg gtggtccttt aggtgagttg cagtatgaaa cgtttagtgc
    19381 tgctcaagca aatattacga tccaagggaa aaatgtacat ccagggacgg caaaagatac
    19441 aatgatcaat gctctacagt tagcaatcga ttttcataat cagcttccag ccgatgaagt
    19501 tccagaaaaa acggaaggat acgaaggttt cttccatttg atggcattgg atgggaatcc
    19561 tgaagaagct tctatgagtt atatcattcg cgatcatgat cgtgaaaaat tcgaagcacg
    19621 caaagcacaa atcacacata tccaagaaga gttgaatcag cgatttgatc aagaacgaat
    19681 caaagtagat atgtatgatc aatattacaa catgaaagaa atcattgaaa aagatatgag
    19741 catcgtggaa ttagcgaaac aagcaatgat cgagcttggt atctctccag tgatcgaacc
    19801 agttcgtgga ggaacagatg gttcaaaaat ctcttacatg ggtattccga cgccaaatct
    19861 atttgccgga ggagaaaata tgcacggacg attcgaattt gtttctttac aagtaatgga
    19921 aaaagcaaca gacgtgattg taaaaattgc agaattgaac acaaagagtt aaaatcgaaa
    19981 aagaacagct tatgacaagg cgttcgtccc aatgatggaa tgtcatctgt ctaaggctaa
    20041 agggcaggac aatggaattg gttgtcccgc cctctttttt gaagagtaaa taggaggtaa
    20101 agaatggaaa agctgctagt tttttataac aaaagttcag ggaaagatga gggtgagaaa
    20161 ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc cagaattata tgtagaacta
    20221 gctgaaactg gcccatcgat tgatgatgcg gaattagtca agaaagcaga agccatagaa
    20281 gctgatactt tagtaattat aggtggagac ggcacgattc atcatatcgt ccaagcgttc
    20341 caaaaaacat tatctcaata ccatgtcgga ttacttccag gtggaactgt caacaacctt
    20401 gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg ctgacgtgat cctggaaggc
    20461 aatgtacgga aaatagacta tggtcaagtc aatgatgaag tcattatctc tacactgaca
    20521 atcggaatct tagcagatac agcagtttgg atcagtcaag aagaaaaaca gcgttacggc
    20581 tcgtggatct ttatcaagaa gttttttaag ttattgctga agaagaaaaa atatcatttg
    20641 gatttagaaa cagacgagga gcattggaaa ggaaaatccc aactgttgac agtcacgatg
    20701 tctaactccg tgggcggttt tacaaatttt gacgactcag cgaccctaga tgatggaaaa
    20761 tttcatgtaa cgatcgtacc ttccttagat attttccgat ttatttttta tttgcctaga
    20821 atcatgagag gcaaattcta tacgatcccc ggcattactt atttcacagc caaacgcatg
    20881 aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg atggagacac gacagatgat
    20941 cttccagttg aattatctgt tgtatcaaaa ggattaacag tttattcacc aaagaaagaa
    21001 gaaaaagctt agaaatagta gttaacagaa agttggaaga agagtaatgg atgtattgtt
    21061 acacaatctt ttgtggtttt accttttcat tgtgaatttt tacttatttt gtctgatggg
    21121 gtatgataaa catcaggcta gaactagcgg ctggcgtgtt cctgagaata atttgatatt
    21181 tgtcagcctg ttaggcggtg gtttgggagg attgatctct cgaaaagttt tccatcataa
    21241 aactcggaaa aagaagttta ctataggatt cgctgcaggt gtacttgttg atttgattct
    21301 catttatttt ttccattaag gagcaggaga tgtcgtctaa aggaacgaaa actaaaatca
    21361 ttctgaatct gcttttgctg attgtgattt ttgccattat ttattattta atcaatcaat
    21421 catttgcaga tatctttgcc gaattgctgt ctaccagtgt tgttgttttg gcagcggctg
    21481 ttatattagg gacagtttac caaatcgctg aagggcgctc aatcaaagaa attgctgaac
    21541 ctttcgcgcc gaattttaca acgaaagatg ggttcttgac ctctagctat attgcgtttt
    21601 accgaatcgt ttcgtttggt acaggaacgc tgatctcgga gatttatttt tataacaaaa
    21661 aaggaatgaa gctatcccag ggagcagggg tgacagcact ccatatgatt atgtacaaac
    21721 tggcagtgat cacttatgca ttagctggct tggtcatcca attctctctt ttttattcta
    21781 atggtccatc aatgatctgg tttatcatcg ctggtatcct tttgacgatc gtgattgttg
    21841 cctttttatt ggcgatgtcc gtcagcttga atgttcaaat attttttgtc agcttatcga
    21901 ataagttatt taaaagtgag cgtttgcgga aatgggtgga tacatgcaat cagcagatct
    21961 actctttaag ggaaacggtc caaaccatta tccaagacag gactgcgcta ttgcggattt
    22021 atctatggaa tatgttaaaa cttgtatttt ggtatgtact tccttatttg attctgattg
    22081 aaaaccatcc taaaatagat tttctactga ccatttcgtt tatcagcttt gcagtagtgc
    22141 tttcaggggt tattcctacg cctgctggta ttggttcctt tgaatttgtc tatttgttat
    22201 tattcagacc agttgttgga acagttgacg cagtttcttc gcttttactg tatcgtttca
    22261 gttcctttat cttgccattt ctctatggat ttgtgtatgt gattgctgaa cggcgaagag
    22321 tgatcaaaga agaaataata gaagtaaaaa aagagaataa agaaaatcaa gggtaggtct
    22381 tttataagat ctaccctttt tatcaaatca aagaaaaacg ttatggataa gataatttta
    22441 cgtttgtttg gctctttttt tatatacata caatcaattt tgttttttta agatttatat
    22501 aagtcgagaa aaaaagtcaa aaaaccatgt gtatattttg accaaaattg accaaagcga
    22561 tataatagtt tttgtaaaga tcaaagaaat aagtgatctt acctttaatt aggagggtat
    22621 acctgtatga atattgagaa aatgactacg acgcttcaag aagcgattgc tgaagctcaa
    22681 cagattgcgg tcactcgaaa acatcaagat atcgacattg cccatgtatg gaaaatcttt
    22741 ttacaaccta atcattttgg tcgaaatttc tatacggatg ccggattgga tgtcgaatct
    22801 tttgaacatg aaattgatcg tctactggat gagtatccag ttgtttctgg tggaaacgtc
    22861 caatatggac aaaacctcag ccagaatttc tttcgattat tgaatgaagc agaccaaata
    22921 cgtgaaagct tcggcgacga gtttctttca acggaagtcg ttattttagc gttgatgaaa
    22981 ttaaaaaatt atccgttaac tgtttatttg aataaaaacg gattatctga aaaagaattg
    23041 cgtaaaaaca tcgaagagat gagaggagga gaaagagtga cctcacaaaa ccaagaagaa
    23101 caatacaaag cattagaaaa atacggcgtt gatttagtac agcaagtcaa aagcggaaaa
    23161 atggatccaa tcatcggtcg tgatgaagaa atccgtgatg tcatccgtat tctttcacga
    23221 aaaacaaaaa ataatcctgt tctgatagga gaacccggtg tagggaaaac ggcaatcgtt
    23281 gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg aaaatttaaa agataaaacg
    23341 attttttcat tagatatggg tgcattgatc gctggagcaa aattccgtgg tgaatttgaa
    23401 gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg atggacgtat cctcttgttc
    23461 atcgatgaaa tccacaatat cgtaggggca ggaaaaacag aaggaagtat ggatgccgga
    23521 aatctgttga aaccaatgct tgctcgcggt gaattacatt tgatcggtgc cacaacttta
    23581 gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg aacgtcgctt tcaaaaggta
    23641 ttagtcaaag aaccaacagt ggaagatacg atcagtattc tgcgtggatt aaaagaacgt
    23701 tttgagatcc accatggtgt taacatccat gacaacgcat tagtagcagc agctacttta
    23761 tctgaccgtt atattactga tcggttctta ccggacaaag caatcgattt gatcgatgaa
    23821 gccagtgcaa cgattcgggt agaaatgaac tctatgccaa cggaattaga tcaagttact
    23881 agacgtttga tgcagttgga aatcgaagaa gctgcactga aaaaagaatc agatgatgca
    23941 agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg aacttcgtga agaagcaaat
    24001 gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca attctgtttc agcaaaacgt
    24061 gctgaaatcg ataaagcaaa acacgaatta gaagatgcag aaaataacta tgatttagaa
    24121 cgcgctgctg tattgcgtca tggtacgata cctcaattag aaaaagaatt gaaggaatta
    24181 gaagctaaag caaaagacag cgagattaag atggttcaag agtccgttac cgaaaatgag
    24241 attgctcaag tcgttggcag attaacgggt atccccgtaa cgaaacttgt agaaggtgaa
    24301 cgagaaaaac taattaaatt gaatgaaaca cttcataaac gagtgattgg tcaagatgaa
    24361 gcagttgatg cggtcagtga cgcggtaatt cgttcacggg ctggattgca agacccaaat
    24421 cgtcctctag gttctttcct tttcctagga ccaactggtg tcggaaaaac cgaattagcg
    24481 aaagcgttag ctgagaactt gtttgactca gaagatcata tggtacggat cgatatgagt
    24541 gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag ctcctccagg ctatgtaggt
    24601 tacgaagaag gtggtcaatt aacggaagct gtcagacgaa atccttatac aatcgtcttg
    24661 ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata tcttgttaca agtcctagat
    24721 gacggacgct tgactgattc aaaagggcga gtagtagatt tcaaaaatac ggttctgatc
    24781 atgaccagca atatcggttc acagttactg ctggaaggcg tgactgctga tggaacgatt
    24841 ccagaagcag tggctgaaca agtcaacacg ctattacgtg gaaacttcaa accagaattc
    24901 ttgaaccgaa tcgacgacac gattttattt acaccattga gcctagacaa cgtgaaagga
    24961 atcgttgaca aaatggtggc gcaattggca caacgtctgg aacatcaaga aatcctgctg
    25021 acaatcagtg atgaagccaa aacgtggatt gctgaaaatg cttatgaacc agcatatggt
    25081 gcaagaccat tgaaacgatt tatcactaag gaagtagaaa caccactagc taaagaaatc
    25141 gttgcaggac atgttatgcc taaatcaaaa gtaacgatta ctttacttga tggacaactt
    25201 catttcaaaa cagaagagct agaagaaatc gtctaatctt ccattgagac tataaaagaa
    25261 aaaaggggtc tgacacaact agtgtcagac ctcctttttt caaataaaca gtgttccaga
    25321 agtagtttct tcgaaaaata agccgaaatt tcttgaagct gcccgcttct gtcacaacct
    25381 cttttattag gtatttttca ctttttctaa tttataactt tcaaagtaac gctcatcttt
    25441 tttactttga gaccatgcaa acaatcccat taaggcagca cctatcgtat ttgtcagcaa
    25501 gtcgcccatc gtatccatca atgctgctcg tccgacaaac agtgtgccat cagaagcagc
    25561 aaaacgttga agattcatgc ctaagaactg gtcgcataag aattcccaga actcccaaaa
    25621 cacgccgcaa agtccagcaa acgcaaagcc gaataagagg aacaaccaag gactggtttt
    25681 tgatatctca gcatctttca tcaagtaacc aatcaatcca tagccaagag ctgtcaggac
    25741 cattggactc accgcatgta agattttgtc ccaaaaagag atgatactga tcaaatgcat
    25801 ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag taaaacaaaa cgattgctgc
    25861 tggtatttta agtttgaaaa ctttcaaaat gacttgtggc atgaaaatca atgcaatccc
    25921 taataaagat tccacgataa atgtgattcc ttgagaagtc gaatattttt gtgtgataaa
    25981 ttcataaaaa ttatagcaga caacgaatac accaaaagca agtaaagcta tttgcacctt
    26041 tttgatttct ttaatcactg aaagtccctc catctaaaaa tctttttact tctgaaagca
    26101 actcaatttc tgaagaaacc acttttccgt tcaatttgat caaacctatt gtatataagt
    26161 tcaggtagtg aaattgattt tcagctgttt cttgtagtgc agcgattttt ttcgggtggg
    26221 ttccgccttg ctgtcgagta tcagtatata agccgatcac tgggatgcct ttcgcataag
    26281 ccacaccgat ttccgatgct accccggcat cgatcgtcag cccatctagt aaagcaatca
    26341 ttaaatcact agccaacact ttttctgtgt cagcaagagc aatcattcga ctgtctgcat
    26401 aagcagtttt gtcattgatt gcttcatttt cttgaggaag atagatcgaa agctcagaag
    26461 agagctctct gatttcttta actaactgtt ggttatataa caaatcactt ttagcaaaca
    26521 ttggtgcggc aaaataaatt ttcatctaaa catcatcctt tttatcaaaa ataatcgcta
    26581 aagtaagctt ccatgtttgg aatgatacgc tctagtgact tcagtgtttc ttcatctgtt
    26641 tctaaccgtt cgattcttgc caaataagaa gcacggcgat aattcatcat caagcaagtc
    26701 aatgtttgga tatccagtcg aacggatttt cctataggtt catttaagac acggacttgt
    26761 ccctgttcat cccatgttaa agcgaagaca ccattattcc aaggagcgac aggatcttca
    26821 atgatgaaat gaaaagcatc agctgttcca acaaacggaa accgttgaag gaattctttt
    26881 acatcaacga tccgagccat aaaatatggt tcgatctgct ctttgatctg actatcttca
    26941 atcaaaaatg ctaaaggctc atttttataa atatctccat gtacccagta gatcatggaa
    27001 aaatgtgcgg aaataaagtt ccataagcca tttcgagctt cttgatcaag atagaacatt
    27061 tcttttacgt gaaatatttc ttcagctacc cagtagaaca gaacacctct tggttcatgg
    27121 ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat tttcgaaacg ccaatactct
    27181 tcccaatgaa aatcactgcg gaataaagca ccatggtttt gttgggcaaa tttgtcataa
    27241 acggaaaata cgtctggatg atcaactggt aatcgctcaa ccataccact tactgggatt
    27301 tgtttaggta gctgtgtatc tctgatttta aaggaaagtt tatcagacat gatttcccat
    27361 cctttacgcc gatagtaggg gatactgtaa ggatacaaat aagagatcca ttgcttattc
    27421 ttgcgcatat tatccaatgc aacgataatt agatcttgca tcaatccatg gttagcatat
    27481 tctggataag ttccaactcc agtcacacca cccattttat aacgtgcacc gtgaatattg
    27541 acttcacaag gatagatagc gatttgagag atcagtttat tttcgtggaa ccatccgaac
    27601 actttcgata cttccaaaat cggttttttg gaacggataa aagctcgttt attctcaaac
    27661 ccgctttcct cgatgtctgc ttcagtcact tggaacacat aggaaagcaa ttcattgaat
    27721 tgatcgatat gttcttgagt gaccggtttt aattcaagat tttctctaaa atctttttga
    27781 tccatttttt catctccatt tattagcttg ataacagtat agcaaaattc tacaaaaaaa
    27841 acttctatag ctgactaatt aaaaactctt taaattactg cttttcgttg gtataatgga
    27901 aagtgctgat tatatgaaaa gaggagacgc tatggatata aagaaaatga aagaacgcca
    27961 agagcagatt cgtaattttt cgatcatcgc tcatatcgac catgggaaat ctacattggc
    28021 cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc gaaatgcaag atcagctgtt
    28081 agactcgatg gatttggaac gtgaacgtgg aatcacgatt aaattaaatg ctgtagaact
    28141 caattacaca gcgaaaaatg gagaaacata tatctttcac ttgattgaca ccccagggca
    28201 cgtcgacttc acctatgaag tctctcgaag ccttgctgcc tgtgagggtg ccgttttagt
    28261 ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc aatgtttatt tagcgttaga
    28321 caatgatttg gagatcctgc cagtcatcaa taaaatcgac ctacccgcag cagatcccga
    28381 acgtgtccgt caagaaatcg aagacgtaat cggaatcgat gctagtgaag ctgtattagc
    28441 cagtgccaaa tcagggattg ggattgaaga tattctcgag cagatcgtgg aatatgttcc
    28501 tgcaccaagt ggagacttag atgcaccgct aaaagctttg atctttgact ctatttatga
    28561 tagttaccgc ggtgttgttc taaatgtccg gatcacggac ggtatggtca aacccggaga
    28621 caaaatcaaa ctgatgagta atggcaaaac atttgatgtt acagaggtcg gggtcttctc
    28681 gccaaaagca gttgctagag actttttgat ggtcggtgat gtcggttata tcacagcaag
    28741 tatcaaaact gtccaagata cacgagtagg ggatacagta acgttagcag acaatcctgc
    28801 cgctgaagct ttaccaggtt accgaaaaat gaatccgatg gtttattgtg gtctttatcc
    28861 aattgatact tctcgttaca acgatttgcg ggaagcttta gaaaaactgc aattgaatga
    28921 tgctgcttta caattcgaac cagaaacctc tcaagcatta ggttttgggt tccgctgtgg
    28981 attcctcgga cttcttcata tggatgtcgt ccaagaacgc ttggaacggg aattcaatct
    29041 agaattgatc acgactgcac catccgttat ttaccatgtt aataaaacgg atggtacgac
    29101 tgctacagta gataacccgg cagattttcc tgaacctgta acgattcagg atgtagaaga
    29161 accattcgtc aaagcacaga tcatggtccc aaatgatttt gtcggtgcag taatggaact
    29221 ttctcaacga aaacggggag aattcattac gatggattat ttagatgatt accgagtaaa
    29281 tgtcgtctat aatattccgc tttctgaaat tgtctttgac tttttcgaca aattgaaatc
    29341 aagcacgaaa ggctatgcct cattggatta tgaaatgtct ggttatcaaa aaagcaagtt
    29401 agtgaagatg gacatcttgc tgaatggaga aaaagtcgat gcattaagct ttatcgttca
    29461 ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa aaactgaaaa aactaatccc
    29521 acgccaacaa tttgaggtgc caatccaagc agctattgga caaaaaatcg ttgcccgttc
    29581 agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt tatggtggag atgtttctcg
    29641 taaacgtaaa ctcttagaga aacaaaaaga agggaagaag cggatgaaac aaatcggctc
    29701 cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa atggacgagg acgaaccgaa
    29761 gaaatagcaa gggtttgttt gaaaacagtg taaaaaataa accatgttta catggatttg
    29821 ccaccggttt gccaccggtg gtttttttcg gtggcaaaaa tcaagaattc tttctaagat
    29881 tttccatgat atcgaccgtt tcatttctca tcttatctgt tacatgcgag taagtatcca
    29941 tcgtaattga aattctgctg tggcccaatc gttcagagat ttctttcatt tttgcgccat
    30001 tttcgagaag aagtgtagca tgagtatgtc tgagagaatg gaagttaaaa gagagggaga
    30061 gtgcattcga tatcctccta gtattccatt tcactacact tggcgtaact agctcaccgt
    30121 cttccttcgt acatactgca tttgaatcaa tgtagagctt tccatacttc attcgatttt
    30181 ctaattgttg tttcttatgt tttttcagaa ttgctagcaa ggtttgtcca ataaaaatcg
    30241 ttcgattgga actgcttgtc tttggcgtac catataccca tgcgccgtca ttctttacca
    30301 tttgtttctc tacagtaatt gttccatttg aaaaatcgac atcatcccac gtcagaccac
    30361 aaacttcgcc aacgcgcatt cccgtataaa atccaatatt caaaggaata tagaaaggat
    30421 gtccttcagg agtaatttct agcatatgat caaagtcctc aagagaaatg atttttagat
    30481 cttttttagt cgttggtcgt gcttcatatt ttggtatttt tacatacagc ataggatttt
    30541 gcttgattaa tccccaagga taaaccgcca tattcagcgc attcttaagg acagagtgag
    30601 taatagtcat tgttttcttc gagtaaccct ttttaaattc agcattgatg aaattttgta
    30661 aaagagcagg ggagagatcc gtaagttttt tctttcctaa ataaccgttt atatgatttt
    30721 tgatggtaaa tcggtagttt tcataggtat tgtattttag atttagttta acgtattcct
    30781 ccatccaaaa atcaaggtat tgttttactc gagtatccgt acctaaaaag tattgtcctg
    30841 tttcgtcaat atctgataaa acttttcgta aagcagcttc ggcctctggt cgggtgtctc
    30901 cgccaacttt ctccactttt tttcttgagc catcatcatt gatatcttcg ccgtttgtat
    30961 aattaagcga gacaaa
//
LOCUS       DAFEML010000026        30914 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFEML010000026
VERSION     DAFEML010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.026"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            49..1362
                     /locus_tag="LP468_001384"
     CDS             49..1362
                     /locus_tag="LP468_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2080928.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            1359..2078
                     /locus_tag="LP468_001385"
     CDS             1359..2078
                     /locus_tag="LP468_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL2080929.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            2206..2757
                     /gene="raiA"
                     /locus_tag="LP468_001386"
     CDS             2206..2757
                     /gene="raiA"
                     /locus_tag="LP468_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL2080930.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            2979..5513
                     /gene="secA"
                     /locus_tag="LP468_001387"
     CDS             2979..5513
                     /gene="secA"
                     /locus_tag="LP468_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL2080931.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            5639..6740
                     /gene="prfB"
                     /locus_tag="LP468_001388"
     CDS             join(5639..5710,5712..6740)
                     /gene="prfB"
                     /locus_tag="LP468_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL2080932.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            6845..7531
                     /gene="ftsE"
                     /locus_tag="LP468_001389"
     CDS             6845..7531
                     /gene="ftsE"
                     /locus_tag="LP468_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL2080933.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            7515..8408
                     /locus_tag="LP468_001390"
     CDS             7515..8408
                     /locus_tag="LP468_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2080934.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            8560..10008
                     /gene="cls"
                     /locus_tag="LP468_001391"
     CDS             8560..10008
                     /gene="cls"
                     /locus_tag="LP468_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2080935.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGGKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            10345..11202
                     /locus_tag="LP468_001392"
     CDS             10345..11202
                     /locus_tag="LP468_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL2080936.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            11317..12237
                     /gene="pstC"
                     /locus_tag="LP468_001393"
     CDS             11317..12237
                     /gene="pstC"
                     /locus_tag="LP468_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL2080937.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            12237..13121
                     /gene="pstA"
                     /locus_tag="LP468_001394"
     CDS             12237..13121
                     /gene="pstA"
                     /locus_tag="LP468_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL2080938.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            13136..13942
                     /gene="pstB"
                     /locus_tag="LP468_001395"
     CDS             13136..13942
                     /gene="pstB"
                     /locus_tag="LP468_001395"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2080939.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            13958..14716
                     /locus_tag="LP468_001396"
     CDS             13958..14716
                     /locus_tag="LP468_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2080940.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            14729..15406
                     /gene="phoU"
                     /locus_tag="LP468_001397"
     CDS             14729..15406
                     /gene="phoU"
                     /locus_tag="LP468_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL2080941.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            15645..16676
                     /locus_tag="LP468_001398"
     CDS             15645..16676
                     /locus_tag="LP468_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2080942.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            16673..17440
                     /locus_tag="LP468_001399"
     CDS             16673..17440
                     /locus_tag="LP468_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2080943.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            17540..19108
                     /gene="liaX"
                     /locus_tag="LP468_001400"
     CDS             17540..19108
                     /gene="liaX"
                     /locus_tag="LP468_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL2080944.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            19405..19725
                     /locus_tag="LP468_001401"
     CDS             19405..19725
                     /locus_tag="LP468_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL2080945.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            19725..20075
                     /locus_tag="LP468_001402"
     CDS             19725..20075
                     /locus_tag="LP468_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL2080946.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            20242..21180
                     /locus_tag="LP468_001403"
     CDS             20242..21180
                     /locus_tag="LP468_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL2080947.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            21195..22025
                     /locus_tag="LP468_001404"
     CDS             21195..22025
                     /locus_tag="LP468_001404"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL2080948.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            22069..23094
                     /locus_tag="LP468_001405"
     CDS             22069..23094
                     /locus_tag="LP468_001405"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2080949.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHHASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            23109..24047
                     /gene="galU"
                     /locus_tag="LP468_001406"
     CDS             23109..24047
                     /gene="galU"
                     /locus_tag="LP468_001406"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2080950.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            24172..24612
                     /locus_tag="LP468_001407"
     CDS             24172..24612
                     /locus_tag="LP468_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL2080951.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            24615..25217
                     /locus_tag="LP468_001408"
     CDS             24615..25217
                     /locus_tag="LP468_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2080952.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(25280..26383)
                     /locus_tag="LP468_001409"
     CDS             complement(25280..26383)
                     /locus_tag="LP468_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2080953.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            26593..27594
                     /gene="ccpA"
                     /locus_tag="LP468_001410"
     CDS             26593..27594
                     /gene="ccpA"
                     /locus_tag="LP468_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL2080954.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            27949..28344
                     /locus_tag="LP468_001411"
     CDS             27949..28344
                     /locus_tag="LP468_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080955.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            28344..28595
                     /locus_tag="LP468_001412"
     CDS             28344..28595
                     /locus_tag="LP468_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080956.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            28638..29033
                     /locus_tag="LP468_001413"
     CDS             28638..29033
                     /locus_tag="LP468_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080957.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            29030..30286
                     /locus_tag="LP468_001414"
     CDS             29030..30286
                     /locus_tag="LP468_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBL2080958.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGQLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            30298..30621
                     /locus_tag="LP468_001415"
     CDS             30298..30621
                     /locus_tag="LP468_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080959.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            30614..30880
                     /locus_tag="LP468_001416"
     CDS             30614..30880
                     /locus_tag="LP468_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080960.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT        10398 a         5320 c         6664 g         8532 t
ORIGIN      
        1 aaaaaataga tcgcttgttt tttcgtatat ttttttaggg cgaataatat gaatcatttt
       61 tggggtagaa ggcttctgac gagagatatt aaagcaatag actgtgagga ggtaaattta
      121 ccaaattatg agaagatcgc agcagtggaa cgtttgggca actggattct ttgtcatcgc
      181 tgtggaatga ggacgtccgt cattgatgga cagcttgcag attacggtta tttttgtaca
      241 cattgtctat atttagggcg atgcgacact caacaagatt tatatttgtt tgatcagcct
      301 gaagcaaaac ctcgagaagt cgtctttttt tggacaggac agcttactga aaaacaaacg
      361 gaaatcgcaa agagaatact ttgccattca gaaaaaagac atcatcttat ttgggctgta
      421 acaggtgcag ggaaaacaga gatgctttat cctattttag tggaaacttt aaaagctgga
      481 ggaagagtag cgatttgtac accgcgagtc gatgtttgta atgaattgtt tttacgctat
      541 cgttatgttt ttccagaaga aaaaatcacg ttgctccatg ggaatacagc aacggcttat
      601 acctttactt cttttgttat ctgtacgatt catcagctat accgttttta tcggtccttt
      661 gatttaatag tgatcgatga gatcgatgcg tttccttata acggggatgc aggattagct
      721 catgctgtgc aaacagcgat taaaccagac ggacgattca tctacttaag tgccacacct
      781 gataaaaagt tactaaagga aatcaagcag acgtttgaca tccacaaact tgctttgcgc
      841 tttcatcggc gtttacttcc tgaacccgtc ttggttttca tgaataattg gcgacaaaaa
      901 tgcaagaaca agaagaagat aaaatctttg gtgcggatca ttcatcaatt aattaaagaa
      961 aaccatatcc ttttattttg tccaagtatc acgatgatgc atcgtttgaa agccacactt
     1021 caagaggctc ttccgagata tgagatcaca gatgtttctt caagagacaa tcagcgggcg
     1081 gaaaaagtcc agaaaatgcg agaagcaaaa tatgacatac tgttaaccac gatgatcctt
     1141 gaacgtggag tcacatttga aagaatatcc gttatcgttt taggagcgga tcatccggtt
     1201 tttactaaat cttctttggt acaaatcgca ggaagagccg atcgtaaagg gccttatacg
     1261 aacagtcaag tatacttttt ctatgaagaa aaaactgcag ctattcgaaa agcttgtcag
     1321 gaaatcaaag aaatgaatga agaagggaag aagatgctgt gaggtgcagt tgctgcagta
     1381 aagatatcgt ccaaaattta acattcagcg agattattgg tgtttcgaaa tacagattac
     1441 ctcagacttg ttcagtttgt cgcgcacaat ttcatttatt ggaaacaaga ggctgttctg
     1501 gctgtcaaaa accaatccat ttcaatctag agagtacgaa aaagaaagta aagtctattc
     1561 ccgtttactg cagtgactgt caagaatgga agaagaaata tccgacctat gattttcagc
     1621 accgtgcctt ttttgtgtac gatgaaaata tgaaggcctg gctcaatcaa tacaagttta
     1681 tgggagatat ccgactagca ggcacctttg catataaatg gacgcagata aaaaaagaat
     1741 acccgacata catctattgt ccaatacctt tatctgaaaa aaggcgaaca gaaagaggat
     1801 tcaatcaagt aagcgagatg ttgaaagcag caagaattcc ttttcagatg ctactcaaaa
     1861 gagagaagca tctgctggct caagcaaaaa acacgcgaaa ggaaagattg gagatgcctc
     1921 aaccttttga acttgcagtc accttttcta agatacaaaa taaaaaaata ttgattattg
     1981 atgatgtcta tacaacagga cagactcttt tccacgcagc agattgtttg caggtcgcac
     2041 agccgaaaat catccgaacc atttctttag caagatgaat tagatgtgga aatttgatag
     2101 cgatttaatt tgcaaataac ctagagttcg atataataga attaagaaga gggaaagagt
     2161 ggtccttctc cttcttgatt gtggtagacg aaaggggtaa tttttatgtt tagatataat
     2221 gtacgcggcg aaaatatcga agtaactgaa gcgattcgcg actacgttga gaaaaaagta
     2281 ggcaaactag aacgctattt cagtgacgca cccgatgcaa cggcgcatgt gaacttaaaa
     2341 gtttatacag aaaaaacagc aaaagtggaa gtaacgatcc cattacctta tcttgtatta
     2401 cgtgccgaag aaacttctcc agatttatac gcaagtatcg atttggttgt tgacaaattg
     2461 gaacgccaaa tccgcaaatt caaaacaaaa attaatcgta aatcccgtga aacgggcatg
     2521 aatactgcag atgctactgc tttattcaat gaagaggacg aaaacgaaaa tgattctgaa
     2581 ttagatatcg tacgtacgaa acgcctttca ttgaaaccaa tggatagtga agaagcagtc
     2641 ttacaaatga acatgctggg acataacttc tttatttttg aagatgcaga aacaaatggt
     2701 acaagtatcg tttaccgccg taaagatgga aaatacggac tgattgaaac agactgatca
     2761 gccttactta aataacaacg aaaacttgca gcagctactg acagctgccg caagtttttt
     2821 tgagtttcct cctcttttag atgaaatatg aataaattat gaagttctta ctttaatacg
     2881 cttaagatat ttcaattatc tataactaat gataaaatga aaagtaaagt ctacatagtc
     2941 tggataatac acagaaggaa aaggagatta cacaacgcat ggccaatttg attcgttcac
     3001 ttatcgaaaa cgataagaaa gaactaaaac gtttagatag cattgcaaaa aaagttgaag
     3061 catacgctga ccaaatggca gcattaactg atgaacaatt acaggcaaaa actgctgaat
     3121 tcaagggcag ataccaaaaa ggagaaacat tagatcaatt acttccggaa gcttttgcag
     3181 tcgtccgaga agcagcaaaa cgtgtattgg ggttatatcc acaccacgta caattgatgg
     3241 gtggaatcgt gcttcacgat ggaaatatcc ctgaaatgcg tactggtgaa ggtaaaacct
     3301 tgaccgcaac gatgccagta tatctaaatg ctctgactgg cgaaggggta cacgtagtta
     3361 ccgtcaatga atatttagca acccgtgact cgacggaaat gggcgaactt tataatttct
     3421 taggattaac agtggggttg aatatcaact caaaatcttc ggatgaaaaa cgcgaggctt
     3481 ataattgtga tatcacttat agtacgaata atgaattagg atttgactac ttgagagaca
     3541 atatggtcgt ttaccgccat caaatggtac aacgtccgct gaattatgcc attgtcgatg
     3601 aagttgactc aatcttgatt gatgaagcga gaacgccgct gatcatttca gggcaagcag
     3661 aaaaatccac agctttatat acaagagcag acaacttcgt gaaacgtttg aaagaagaag
     3721 aagattataa aatcgatgta caatcaaaaa caatcagttt aaccgaagca gggatcgaaa
     3781 aagcagaaga aacattcggt ttggataact tatacgacat tgaaaatact gcattgaccc
     3841 atcacttgga tcaagcattg agagccaact atatcatgct tttagatatc gattatgttg
     3901 tccaagacgg aaaagtactg attgttgacc agttcactgg tcggatcatg gatggacgcc
     3961 gttattcaga tggacttcac caagcaatcg aagctaaaga aggcgtagag atcgaagacg
     4021 aaacgaaaac catggcgacg atcactttcc agaactattt ccgtatgtac aagaaacttg
     4081 cgggaatgac tggtacagct aaaacagaag aagaagaatt cagagaaatt tataacatcc
     4141 aagtatacca gattccgaca aatcgtccgg ttatccgtga tgatcgtcca gatttgcttt
     4201 acccaacatt acaaagcaag ttccacgctg tcgtgcaaga tatcaaagat cgctaccgca
     4261 aaggtcaacc tgtgttagtc ggaactgttg cggttgaaac atctgagtta ttatcagata
     4321 tgctgaatca agaacgtatt cctcatgaag tgctgaatgc gaaaaatcac tttaaagaag
     4381 cagagatcat catgaatgct ggtcaaaaag gtgctgtgac gattgctacc aacatggctg
     4441 gtcggggaac agatatcaag ttaggacttg gggtaagaga acttggtggt ctagcagtta
     4501 tcgggacaga acgacatgaa tctcgtcgta tcgataacca gcttcgagga cgtgcaggac
     4561 gtcaaggaga ccctggtatg tcacagttct acttgtcatt ggaagatgat ttgatgaaac
     4621 gattcggttc agaacgaatc aaatctttct tagatcggat gaagatcggt gaggaagatg
     4681 ctgttatcca aagcaagatg ctgacgaaac aagtagaatc tgcacaaaaa cgtgtagaag
     4741 gaaataacta tgacacacgt aaaaacgtct tacaatacga tgatgtgatg cgtgaacaac
     4801 gtgaagtaat ctataaacag cgacaagaag taatcatgga agaaaaaagc ttatccaagc
     4861 cactaatgaa catggtcaaa cggacaatca gtcgtgtagt agatgcgcat acacaattag
     4921 agaaagaaaa ttggaatttg gaaagtatca tcgattttgc cggcagtact cttgtccatg
     4981 aagatagtat tactcttgca gatatcgaag gaaaaacagc tcaggagatc aaagagtatc
     5041 taaacgaacg agcacaagaa gtatttaata ccaaagcggc tcaactaaat ggtccagagc
     5101 aactgttgga atttgaaaaa gtcgtgatct tgcgtgttgt ggactctaaa tggacagacc
     5161 atattgatgc aatggatcaa ttacgtcagt caatcggctt acgtgcttat ggacagaaca
     5221 atccattagt cgaatatcaa acagaaggct ataagatgtt tgaagatatg gtaggcgcca
     5281 tcgagtatga agtcactcga atctttatga aagctgagat ccgtcaaaac gtacagcgtg
     5341 aacaggtttc tcaaggaaca gcttctcact cagaagacgg agatgccaaa gaaaatagta
     5401 atactagcgc gaaaaaacag ccaatccatg tgaacaaggt cggaagaaat gatccttgtc
     5461 cttgtggaag cgggaaaaaa tataagaact gtcatggaaa aaatgcaaac taatttctga
     5521 cagcaggatt ggtgagacaa attctttttt taagaattcg tctcaccttc tttctgttat
     5581 ttgctgattc tgttagacta gatataatga aaaaagtata gtgaaagaag gaaaaaacat
     5641 ggaaatatcc gaaattcgaa atctcctgac agaaatgcag gaaaaggtca caagcttcag
     5701 gaggtctctt tgacttagac cagctggaag aagacattgc ggaagcagaa gcaaaaatgg
     5761 ctgaacctgg tttttgggat gatagcgaag ctgctcaaaa agtgatcagt gaaaacaatg
     5821 caaataaaga aacttatgat caattccatt ctcttgctga agaactggaa gaaatcgaat
     5881 tgatggtgga gatgttgcag gaagaacctg atgcagccat gcaagaagaa gcagaaacac
     5941 gtatcaatgc gctagatgaa aaaatgaaga catatgaatt atctatgttg ttagatggtc
     6001 cttatgatcg aaacaacgcc atcgttgaat tgcatccagg ggctggcgga acggagtccc
     6061 aagattgggg cagtatgctt ttacgtatgt atacacgctg ggcagagcag catgggtatc
     6121 aagtagagac actagattat caagcaggtg atgaagcagg aatcaagagt gtgaccctac
     6181 tgatcaaagg acacaacgca tttggttatc tgaaatcaga aaaaggtgtt catcgccttg
     6241 tacgtatctc gccttttgac tcagcgaaac gacgtcatac ttctttttgt tcggtagatg
     6301 tgatgccaga gcttgatgaa acgatcgata tagaaatcaa tccagatgat ttgaaaatcg
     6361 atacgtaccg agcaagtggt gcaggtggtc agcacatcaa taaaacagaa tctgctgtac
     6421 ggatcactca cttgcctaca ggaacagtag tagctagtca ggcacaacgt tcacaattga
     6481 aaaaccgtga gcaagcgatg gggatgttaa aagctaagct ttatcaatta gaagtggaaa
     6541 agaaagaaca agaagcagct gcacttcgag gagaacaaaa agaaatcggc tggggttcac
     6601 agatccgttc ttatgttttc catccatatt ctatggtaaa agaccatcgg acaaacgtag
     6661 agacaggaaa tgtccaagca gttatggacg gtgaccttga tttatttatt gacggctatt
     6721 taaaaatgca tctacaataa gaacccattg ttaaattgaa ataaaattgt aagattttgc
     6781 aagcatgttg aaacattgcc atgctataat agctaaagac tgaaaaagat atggagagaa
     6841 cgccatgatt gaaatgaagg atgtaatgaa gaagtactca aatggtacga ccgctatccg
     6901 caatctctca attgtcatcg aacaaggaga gtttgtctat gtggttggtc cgtctggagc
     6961 cggtaaatct acattcatca aattgatgta tcgagaagaa aaagcttcaa aaggaacttt
     7021 gaacgtcgca ggtcatgatc taatagcaat caaaaaccgc gaagttcctt atctacgcag
     7081 agaaatcggc gtggtgttcc aagactataa attattacca agaaaaacag tatatgaaaa
     7141 tgttgcgtac gctatgcaag ttatcggcag aaaacctcgg gatatcaaaa aacgagtaat
     7201 ggaagtgctg gaccttgttg gtttgaaaca caaagttcga gtctttccta gcgaattatc
     7261 cggtggggaa cagcaacgtg tctctattgc tcgggcaata gtgaatacgc ctaaagtact
     7321 tatcgcggat gaaccgacag gaaatctgga tccagaaaac tcatgggaaa tcatgaaatt
     7381 attagatcgg atcaatgccc aaggaactac tgtcgtgatg gctacacata acagtacgat
     7441 cgtaaatacg attcggcacc gagtaattgc tatcgaaaac ggccgcatta ttcgagatca
     7501 agcggaaggg gaatatggat acgatgatta gaaccttttt ccgccattta ttagaaagta
     7561 tcaagagttt gaaacgtaac ggctggatga cagttgcttc agtcagtgcg gtaacgatca
     7621 cattgacttt agtcggtgta ttcatggcag ttatcatgaa cgcaactaaa ttagctcaag
     7681 atatagaagg aaacgttgat gtctctgtat tcgtagatat cggtacaaaa gacgaagaga
     7741 tgaaaaagct agaaaaagaa ttgaatgact tagatcatgt taaaaaagtt gaattttcaa
     7801 gcaaagaaca ggaattgaaa aaaatccaaa acgaaatggg tgattcctgg aaattgtttg
     7861 aaggtgacaa taacccgtta tatgatgtgt atgtagtaag tgctactgat ccttcttata
     7921 caaaacaagt agcagaagaa gcagcagatt tgaagaatgt ttctcgttct gattacggtg
     7981 gagcttcctc agatcggatt ttccaaatcg ctggtgcagt tcggacatgg ggattagttg
     8041 cagcggcatt gctgctgttc gtagcgatgt ttctcatttc gaacacgatt cggatcacga
     8101 ttttgtctag acagcgtgaa attcaaatca tgcgtttagt cggtgcaaaa aatggatata
     8161 ttcgctggcc gtttttcctt gaaggtggct ggatcggtct gatcggtgcg attcttccga
     8221 ttttgatcat cacatttggt tatgcatggt ttttccaatt gatcaatcca tcattattac
     8281 gttcccatta ttcattgatt catccacaaa atatcgtttg gaaaatcaat cttttaatgg
     8341 tcggcattgg tgtgatcatt ggttcacttg gctcgatcat ttctatgaga cgtttcttga
     8401 aattctaata ccacaatata aataaaatga gaaagttgga cagtttcgtt ccagctttct
     8461 ttttttattg gctaggagaa tagaaggaag cggctttttt ccctttactt taaaaaacaa
     8521 cttgggtatt cttaagttgg tagaagaaga ggtgaagccg tgaaaattat cgttgacaat
     8581 ttttttacga tccttttgat tatgaatatt ttgctttcct ttatcatcgt ttttcgagaa
     8641 agaaaggaaa ctgctcaaac atgggcatgg gtgctcgttt tgatgttcat tccagttgta
     8701 ggatttattt tatatatttt tttaggaaga gggatttcca aagagaaaat ctttgatttg
     8761 aagatccaag ggaaaatcgg taagaacctg gaaattgaag aagacaaaca ggcattgatg
     8821 cgagggcttt atcctcatcc gcctactgga caagtagatg tgaaacaatt gatctatatg
     8881 ctcacggtat ttgaaagtac gctctatacg actaaaaatg aaatcacttt atttacagat
     8941 ggtcgtgaaa aattcgatgc gctgattgaa gatatcaagc aggcagaaga ccatatccac
     9001 ttccagtatt atatttatcg cagtgatgca ttaggtgaag aagttcgaga tgcattgaca
     9061 gaggcggcaa gacgaggggg aaaagtcaga gtccttcttg atgcatgggg ttccacacaa
     9121 gtttcttcca gcttttttca gaatttgaaa aaagcaggcg gagaagtcgc atttttcttt
     9181 cctctatttg ttccgtatat taatcctcgg atcaattatc gcaatcatcg taaaatcgta
     9241 gttattgatg ggaaaatcgg atatacaggt gggttcaatg ttggaaatga atatctagga
     9301 ttggtaaaga aatttggtta ttggcgagac aatcatttgc gtatttacgg agaagcggtg
     9361 tataccttgc aaaaccgttt tttgatggac tggaattctc agcatacaaa agaagtaggc
     9421 tattctccca aattttttcc gtccattcac tctactggtg atatagctgt tcaaatcgtg
     9481 acaagcggac cagataccga acatgaacaa atcaaaatga cttatttgaa aatgatttcg
     9541 ttagccaaac gggagatatt gatccaaacg ccttattaca taccggatgg atcgattcat
     9601 gaagcactga agttggctct tctttcaggc gtaaaagttc atatccaaat acctaacaaa
     9661 ccagatcatc ttctcgttta ctgggcaacg tattctttcg ctgcagagct aatcgagtat
     9721 ggagcaagga tcgaaacata tgagaatgga tttattcatg caaagacgat gattatcgat
     9781 ggtggcattg tttcagttgg ctcagcaaat atcgatgttc gttcatttcg cttggacttt
     9841 gaggtcaata cactggttta tgatgaacga atggcttcac gtgtaagaaa agcttttttt
     9901 gaagactcga aaatttctac gcatctcaca aaagaaatgt atgaaaaccg aggaataatc
     9961 atcaagatga aagaaggatt agcaagattg atttcgccgc tcctttaaaa cataaaaagg
    10021 acatgagaac catcaacaga tggagatctc gtgtcctttt ctaacggggc catttctgag
    10081 agtacgtcag aaatggagaa agcgtctcgc atgagcgaaa ttaactttgg ggtatctctt
    10141 gttttttggg gaaagcaaga aataagctaa tatatgctat taaaagagac acatttcaaa
    10201 gccagtatag catagaaact tttaatgaga tagttttttt tacaattatg agaatttatt
    10261 ttgttattta atgattttga ttcgttttca tcaagtaatg aaaatgataa aataaacata
    10321 ctttaggatt aaaggagatt tctaatgaaa aaacttaaat tattcttacc aataatagga
    10381 ttagctattc ttttatcagg ctgttcaaag tggattgatc gaggagaatc cattacggct
    10441 gttggctctt ctgctttaca gcctttagta gaaacagttg ctgaaactta ccagacagaa
    10501 aatcctggaa aattcatcaa tgtacaaggg ggcggaagcg gaactggttt gtctcaagta
    10561 cagtcaggag cagtcgacat cggaaactct gatttgtttg cggaagaaaa atcggggatc
    10621 gatgcctcag cattagtcga tcatcgagta gcagttgttg ggatcactcc tattgtgaac
    10681 aaggatattg gcgtaaaaga catcagtatg gaaaacctga aaaaactatt tacaggcgag
    10741 atcaaaaact ggagtgaagt cggtggaaaa gatcagccag tagttatatt gaaccgcgct
    10801 tcaggaagcg gaacccgtag cacgtttgaa aaatgggtat tggacggaga aacagctgtt
    10861 caggcacaag aacaagattc aagcggaatg gtgcgccaga tcgttgccga cacacccggt
    10921 gcaatcagct atgttgcttt ttcttatgtt tccgatgatg tagatacgtt gaatgttaac
    10981 ggtgtagaac cgacagatga aaatgtgaca acgaacaaat ggacgatttg ggcatatgag
    11041 catatgtaca caagagatca tccaaaaaaa ctgacaaaag aatttttaga ctatatctta
    11101 tctgatgaag tacaagataa catcgttgga gaactaggtt atatccctgt ttctcatatg
    11161 aaagtcgaac gtgattggca aggaaatatc gttaaagagt aatctttaca caaaatttac
    11221 aaacttagct aaacttttac atgttattaa aaccaaattg atgttcaatt tgtacactga
    11281 gtgagtatgt taaacctgat taagggggag tcatctgtgg aagatgtgaa aaaagtatta
    11341 ttaacaaaat caaaacgttc aaaaatggaa cagcgtggaa aattcatcag ttttttatgt
    11401 atcgcgctga tcgtgttggt tgtattatct attttttatt ttgtagctag taaaggattg
    11461 gccacctttt ttactgataa gatcaatgta tttgattttc tgtttggtac agattggaat
    11521 ccaagccaaa tcggagcaaa tgggaaacca atggtagggg cattgcctat gatcacaggt
    11581 tcgtttattg tgaccttttt atctgctatc gttgccacgc catttgccat tggtgcagca
    11641 gtattcatga cggagatctc tcctaaaaac ggaacgaaga tcttacagcc ggtcatcgag
    11701 ctgcttgtag gtattccttc tgtcgtttat ggttttatcg gtttatcagt tatcgtgcct
    11761 tttgtcagaa gtatttttgg cgggactggg tttggtatct tagctggtac atttgtgttg
    11821 ttcgttatga tcttgccgac tgtcacaacg atgactgttg atgcattaaa ggcagtgcca
    11881 cggcactatc gggaagcttc attagcgctt ggtgccacaa gatggcaaac aatctacaaa
    11941 gtcgtgctac gagcagccgt gcccgggatt ttaacagcag tcgtttttgg tatggctcgt
    12001 gcgtttggtg aagccttagc tatccaaatg gtcatcggta atgcagcatt gatgccaaca
    12061 ggtcttacta ctcctgcttc tacattgacg tccatcttaa caatgggaat cggaaataca
    12121 atcatgggaa cagttgaaaa taatgtgtta tggtcattag cgctgatctt gctattgatg
    12181 tcattattct ttaatatcgt gatccgtatg attgggaaga aaggagagct gaaataatga
    12241 acgcaaaacg ctcagataaa attgctacag gtgttttata tatagtttcg gggatcatcg
    12301 tattgatttt agcagcttta ctactttata tcttagttcg gggaataccg cacatttcat
    12361 ggtccttctt gaccgaacct tccaaagcct accaagaagg cggtggaatc gggatccagc
    12421 tatttaactc gatttatttg cttttgatca cgatgatcat cagttttcct atttctttag
    12481 gtgcgggtat ctatctttca gaatatgctg gaaaaaactg gctaacagat gtgattcgca
    12541 cgtcgattga aatcttgagc tcgttgcctt ctgtcgttgt cggtttattc ggtttcttgg
    12601 ttttcgttat tcaattccag tatggtttct cgattatttc tggtgcattg gctttgactg
    12661 tattcaactt gcctcttttg actagaacag ttgaggagtc tttacaagcg gtccattaca
    12721 cacaacgaga agcaggattg gccttaggtt tgtcacgctg ggaaacagtg ataaaagtgg
    12781 tggttccaga agcgacacca gggattttga ctggtgtgat cctaagttct ggaagaattt
    12841 ttggtgaagc agctgcattg atctatacgg ctggacaaag tgcacctgcg ttagatttta
    12901 cgaactggaa tccattaagt gtttcaagcc cgatcagcat tttccgtcaa gctgaaacat
    12961 tagctgtcca tatttggaag atcaatacag aaggcacgat gcctgatggt gtttctgttt
    13021 cggctggcgc ttctgccgtg ttgattattg ctgttttact gttcaacttc ggcgctcgtg
    13081 cgattggcaa acgattatac cgaaaaatga cttcagccta aggagaagaa gcaaaatgaa
    13141 aaaatataac tggaatgaaa caaatgtcat caccatgcca aaagagaaag aagtagcact
    13201 atatacggat gatctacatg tctggtatgg cgacaatgaa gcaatcaaag gagtggatct
    13261 ggaatttgaa aaaaataaga tcactgcact gattggtcct tccggctgcg gaaaatctac
    13321 gtatcttcgt tcgttgaatc gaatgaatga tgggatcgct aatacgaaaa tcactgggaa
    13381 aatcatgtat caaggcgtag atattaatgc gcctcaagtg gatgtttatg agatgcgcaa
    13441 acggattggc atggtttttc aacgtcctaa tccgttcagc aagtcgattt atgacaatat
    13501 tacatttgct ttgaaacagc acggcgaaaa aaacaaaaag aaattagatg aaatcgttga
    13561 aacaagcttg aaacaagctg ccttgtggga ccaagtaaaa gacagcttgg acaaaagtgc
    13621 cttggcttta tctggcgggc aacagcaacg tttatgtatt gctcgtgcga tcgcgatgaa
    13681 acctgatatc ttgctgctag acgagccggc aagtgctttg gaccctattt cgacaggaac
    13741 ggttgaagaa acacttgtaa acttgaaaga agactatacg atcatcatcg tgacgcataa
    13801 catgcaacaa gcagctcgta tcagcgacta tactgccttt ttctatttag gaaaagtaat
    13861 ggaatatgac aaaactaaca agatatttac cagaccaaaa attcaggcaa ccgaagatta
    13921 tgtgtccggt cattttggtt aagacggagg cctcaacatg acaaaagaga ttatttcatc
    13981 taaagatctt catctgtatt atggaaagaa agaagcacta aaagggatcg atctaagctt
    14041 caatcaaggg gaaatcactg cgatgatcgg tccttctggt tgcggaaaat ccacttatct
    14101 gcgttctttg aaccggatga atgacctgat tccgaatgta acgatcaccg gaagtgtttt
    14161 atataaagac aaagacatct atggtccaaa aacagatgtt gttgaactaa gaaaagaaat
    14221 cggcatggta ttccagcagc caaacccatt tcctttttct atctatgaaa atgtcatcta
    14281 tggattgaaa ttaaaagggg aaaaagataa aaaagtcctt gatcaagtag ttgaagaaag
    14341 cctgaaggca gcgtctgttt gggatgatgt gaaagacaaa ttgcataaaa gtgctttatc
    14401 tttatccggt gggcagcagc agcgtgtatg tatcgcacgt gttttggcag ttaatccgga
    14461 aatcatctta ttggatgaac caacaagtgc gcttgatcct gtttctactg ggaaaatcga
    14521 aagtatgctg ttagaattaa gagagcggta tacgatgatc atcgtgaccc ataatatgtc
    14581 tcaagcttca cgtatttcag ataagacggc attcttttta gatggtcact tgatcgaata
    14641 caatgatacg aagaagatat tcatgaatcc agaaaaacaa gagacagaag attatatttc
    14701 aggtcgattt ggataaggag gaaacggaat gctacgtaca caatttgaag aagaattgct
    14761 gaatctccat aatcagttct acgaaatggg gatgatggtg agcagcgccg tgcacaagtc
    14821 agttcgtgca tacatcaaac acgataaaat cttagcccaa gaagttatcg aaaacgatat
    14881 aaatatcaat aacatggaaa cacgcttgga gaagaaaagt tttgaaatga tcgcattgca
    14941 acagccagtt acaactgatt tgcgtatgat cattacggtc atgaaagcta gctcggattt
    15001 agaacgtatg gccgatcatg cggtgtctgt tgctaaatcc acgattcgcg taaaagggca
    15061 gacgagaata ccggaaatcg aaaaagagat ctccgatatg tccgattatg tgaaaaaaat
    15121 ggtggacaac gtcctagttg cttatgtcaa aacagacgaa aaagacgcac gtacgatcgc
    15181 caatatggat caaagagtca atgactattt caatcgaatc tataatgcaa caatcaaaaa
    15241 tatgcaggaa aatcctgaga cagtcatcag tggaacagac tacttgaatg ttgccagtta
    15301 tctagaacgg atcggagact atgtgacaaa catctgtgaa tggatcgtct acttggctac
    15361 agggaaaatc actgagttaa atacgaacca caatgagatt ttctaaactg aagctgtgat
    15421 tatgccgttt gtttaggaaa agaggttgtg aaatcagcgg ttgtgaaaaa gctgttctgc
    15481 atcaagtaat aagaacagtc aaacaaaaaa atagctcctc atatttttcg tttggctgga
    15541 cttattaccg cagatgcaag cttttgaaca ccgtttattc gggaaagggt ttgtgacaaa
    15601 acatgtcaca aacccttttc atcatttcat agaaaggata aagaatgcaa aaaaaaatta
    15661 gcatcatcac tatatttttt atttgtgtgc ttacttcatg ggttattcag catcaagccg
    15721 ctttatatga agtacctgtc atcgagatag aaaaagtacg aataaaagag gatcatcaat
    15781 tgattacagg aaaactgatg aacacggatc aaaaaggaga atcgatttat ttatcggttc
    15841 cttatcaaaa aaatcaaata gaaacagcaa atataaaagc gagacaaatg tatctagtcc
    15901 aaatgcatgg agatgaatgg cagctagtag caaaaaaaaa tgatggctgg cttttcttct
    15961 tcacaagtat cttcattggc gccatgttgc ttattggtgg aaaacagggt ctatttgctt
    16021 taggaagtct catcatcaat atcgttttac ttttactttt gttgctcatc tttactaaaa
    16081 cagaagggat ttctctatta aatatatcta tcctgttcgt cgttataggg atgattatta
    16141 gcatattggc tttagatgga tggaatagaa gcagtataat caaaatttca gctgcagtta
    16201 cgagtgtttt tttagcattt tttatttgtc ttttgacaat gaatcattgg aaagaccaag
    16261 gactgcgcta tgaggaactg aattatctga cacgaccgta tcgttctgtt tttctttcta
    16321 gcgtactgat tggaacagct ggaggaacac tcgataccgt tatcacagtc attgcgacat
    16381 tagaagaatt gactaagcga caaccagaaa taacagcgaa acagttatgg ctttcaggaa
    16441 ggcaagtggg tcgagatgtg attggctcga tgaccaatat ccttttgttc gtctatatca
    16501 gtgggtcagt tccatcgctt cttttatatt taggaaatca atggtcgttc aaagaaacga
    16561 tagaacagca tttatcattg gaatttttac gcgtcattgc tggcagctta ggaatagtat
    16621 tatcgatccc tatctcggtc ctcttttttc tgactgtaag gaggctgaaa cgatgaatgt
    16681 acttattata cttgttggga ttttagcaat cagcgtgcta cttattggcg gtacgcaagg
    16741 tatgtatatt cttttaggct tattcatcaa tttagggatc tttttcctgt tgttattcgg
    16801 ttatcatcag aagtggccga tactggcatt gtcggtcata ggatttttat tgattgctgt
    16861 ggttatctta ttttttatca acggttataa tctaaaaatg cgtgcagctt ttgtgagtat
    16921 actgatcttt ttattttgtt tcctactatt gcttcctatc actgattttt tagcaatcca
    16981 aggttttaca tcggtagaac tagaagaatt atctggctta gataagactt tagcgattga
    17041 ttttagatta cttacgagat cgttgcttct gattagtctt agtggtgctg ttttagatgc
    17101 gagtgtagca atttctagtg ggacattcga agtatatcag gcaaatccgc aattatcttt
    17161 ttaccaattg cgccattcta gtttcgctat tgctaaaaaa atattggcgt caacagtaat
    17221 gacacttctt tttgcattca tgggaagttc tttagcgttg atcctctggt ttattgattt
    17281 agacattcct tttcagcaag tgatcaatga aaaatcattt gttctagaat atacgatggc
    17341 tattcttacc acattgtccg cactacttgt tcttccttta acctgcgtga ctacagcata
    17401 tctctttaca aaaaagaaag aacaactcaa gatggagtaa aagttacaac ttaagtccta
    17461 tgacattttt actgaatcag tgcataatat ggatgtaagg aaaagcttgc aaacaatttt
    17521 gcttaaggag gcaatttcca tgaaagaaag agaacgtatt ttagatttag tgaaaaaagg
    17581 aatcctttcg actgaagaag gcttagattt attagaaagc atggcaactg aaaaagacga
    17641 aaagcaaatc aaaaaagaag cagacaaggt aactgctagt cataaagaaa aagatcaggc
    17701 aagtcaattg atcgataaac ttgaaaacgg cgaagaagaa atttctgagc cagttgatcc
    17761 aaaggaaaga gaaagacaag atcaagaaaa cttagaaaag atcttagatg aactagcaac
    17821 tgaagcgaat aaaacttcgg cgcgtctaga tgaagtaaat gctcaattcg ctgacaataa
    17881 ggcagcacgc aatgagaaac aggaagcatt gatgcagctg aatacaaaag aagaattagg
    17941 cgagttgaca gaagaagaat tagcacagcg tcagacgtta gaagcagaaa tcaaagaatt
    18001 agaagctagt ggcgatacac tgttagaaga acaattgaaa ttagaagcag aattaaaaga
    18061 tatccgtaag aatcaatggt ctgagaaaaa agaaacgttt actgataagt ttgaattgcc
    18121 agatgattgg aaagatcaag caacagatac actgaatcaa gtaggcgaaa aaatgtcaga
    18181 agctggatca cagttaggca aattcttgaa gaaaacattc caaactgttt cagaaacagt
    18241 gaatgacaac atggaatgga aagatgtcag cttacgtgtc cctgggattg cgacaacgaa
    18301 atttgagcat gaattttact atgaagctcc tgcagcaagt atccttgata tcaaggcagc
    18361 aaacggaaac gtgacgttaa aaacgtggga cagcaacgat gtgaaagttg aagctaagat
    18421 caaactttac ggaaaaatgg gtgctgaacc atttgaagca ttctctgaac ggagccagat
    18481 tgaggttaat gaagatcata tctccttcca aattccaaat aaacgtgtgc gtgcagacct
    18541 tgttttctac ttacctaaac gagtatacga ccacgcagct attaaacttc taaatggcaa
    18601 catcatgatt gaaacattgg aagctaaaga tatttataca aaatctacga atggtaacat
    18661 catcgtggac caattaactg caacgatgct ggaagtagaa ggtgtaaacg gcaatatcga
    18721 tattcgaaac gggaacatct tagattctat tatcgaaaca gtaaatggta cagtgacatt
    18781 tggtgcgaca gcagaaaacc tttctgtgtc tttggtaaat ggtgatgtac gtcttacgat
    18841 taaagaagat aatttgaaaa aagtagaagc aagttcagtg aacggaaatg tcaaagtcgc
    18901 tttaccagat ggcatcggtt tggaaggaca tgctaaaaca agtcttggaa gtatcaacag
    18961 ccgtctgtcc aattacgaag tagttcgtga gaaaaaagaa cggacaaacc aaatgttgca
    19021 attccgtcgt gtttcagatg gtgaaatcgc gcaagtgcaa ctttcaacga caacaggaag
    19081 tatctattta aaagatacag ataaataaag aggttgtgaa agagatgttc agccttgagc
    19141 aataagaagc gattttgtaa aatagcttcc cctattttac aaaattgtgc cttattgccg
    19201 atagtctatc tcttgaacac cgtttaccaa gagattatga acctgccaat tatcgccgag
    19261 tcacaaggaa taatttcaga aaaagctcgt cacgttttat gaatatggta atttgtgacc
    19321 gagaattttg cagaaagaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt
    19381 aaaatagtag aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc taataaaaat
    19441 gttgttttga cagggacttt agcaggaata ggagaataca tcgggattga tccgactgtt
    19501 atccgtgtgc tttatgtatt cctgagctta gttgcttttg gaagtccaat tattttatac
    19561 attttattag ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac
    19621 aatgcatatt atgaaaaaaa caattatcgt gaacaaactc gtgaacaaac aaaaaaacgc
    19681 aaagaagcgg aaaaaatcga tgatgacgaa tggagtgact tttaatgtcg tactttcaac
    19741 gtattttagt taatacgtta acattcatat cattggctgt tctttttcct gcgatggtcc
    19801 atgtgagcag tatttggacg gccgttcttg ccagcttcgt attgtctgtg ttgaatatgt
    19861 ttgtcaaacc gattttgacg atactgtccc tgccctttac attagtcaca ttgggattgt
    19921 ttacgtttgt tatcaatgca gcgattctta aaatgacctc cttttttgtg ggagcagaac
    19981 attttagttt ttcttcattc ggtgcagcgt tgttagtagc tatcttgatg tcgcttgtca
    20041 atgtaattgt cagcgaacat aacagtagaa aataaaagaa agctgtgccg aactatcggc
    20101 gcagtttttt tatttagaat caggaatgcg ttttctatta cattggtaat taaataaaaa
    20161 cgtttttttt aattggtagt acttttggct agacaatgat aaaatgatag agaacactct
    20221 aatagaaatg aggtagcatg aatgtcagaa gttgtaaaag ttagccaatt agtgaaaaaa
    20281 ttatctttgg aaatcgtgac aggcgacgag aaaagcttag accgtgtcat cgtaactggg
    20341 gacatctcac gcccaggact agagttgact ggttatttta attattattc ccataatcgt
    20401 ttacagctat ttggcagtaa agaaatcagt tttgcggaac ggatgatccc agaagagcgt
    20461 ttgatcatca tgagaagatt atgtagtgaa gatatgcccg catttattat ttcaagagga
    20521 ttaccagctc cagaagaaat gatccaggca gcaaatgaaa atgggatagc tgtactgcgt
    20581 tctcccatct caacttctcg tttattagga gaattatcca gttatttaga tggtcgcctt
    20641 gcccctcgaa caagtgtcca cggtgtttta gtggatgttt acggattagg tgtactgatt
    20701 caaggtgaca gtgggatagg aaaaagtgaa acagcgttgg agttgatcaa acgcggccat
    20761 cgattgatcg cagacgatcg agtagatgtt tatcagcaag atgaattaac ggtgatcgga
    20821 gaaccgccta aaatcctgga acatctgatt gaaatccgag gaatcgggat cattgatgta
    20881 atgaatcttt ttggtgcgag tgcggtacgt ggctctatgc aagtccagtt ggctgtttat
    20941 ctggaagcat gggcaaaaga taagaaatac gaccgtctgg gctctgaaga cacgaccgtt
    21001 gaaatcgcgg aagtgggcat tccacaaata aaaatccctg tcaaaacagg acgaaacgtt
    21061 gcaatcatca ttgaagtagc cgcgatgaat ttccgtgcac gtacaatggg ctttgacgca
    21121 acgaaaacat ttgaagaaag attaagtcgc ttgattgaag aaaactcagg caacgactag
    21181 caaggagtga caatatgtta gcacaaatca atcgagttgc ttttgagctt gtagggattc
    21241 ctatctactg gtatgcattg atcatcgtat caggtatcat tatcgctatg tggcttagca
    21301 gcagagaggc tgttcgggta ggattaaaag cagatgatgt gacagatttt atgttgtggg
    21361 gattgcctat ctccattatt ggcgctcgct tatattatgt tttatttgat cttccccagt
    21421 atatagctga tccaatccaa atattcaata tccgttcagg aggcttagct atttatggcg
    21481 gactgattgc aggcgcgatc acgctgtatt tttttactaa atatcatttt atttctttgt
    21541 ggactttttt agatatcgct gcaccaagtg tattattagc acaggcaatc ggtcgttggg
    21601 gaaatttcat gaaccacgaa gcatatggac cagacacgac gcgaagcttc ttagaaagtc
    21661 tgcatttacc gcaattcatc attgataata tgtatatcga agggatctat cgtcaaccaa
    21721 catttcttta tgaatcactt tggagtttga ttggatttat tttgcttttg tttttacgaa
    21781 agaaaccaca ccttttgaaa aaaggcgaag tccttttatg ttatctaatg tggtatagtt
    21841 tcgggcgttt ctttattgaa ggattacgta cagacagtct ttacttttta ggtgtgatcc
    21901 gtatttctca attattatct gctgtgttat ttgtcggtac attgattcta tttatttggc
    21961 gcagaaaaaa aggaaattta ccggattatg accgctcatt aggaaaaaat caacaaatta
    22021 tctgattttt agagcgttaa aaatgaaaaa aatttcagga gtggtaaaat gaattataga
    22081 gtagcggttt taggaccagg ctcttggggt actgctttgg cacaagtcct cgccgaaaac
    22141 ggacatgacg ttcggatttg gggacatcat gcttcacaag tagaagaaat caacacccaa
    22201 cacacgaatc aacgttattt accagatcat tatctacccg attccatcca agcattcacc
    22261 aatatggaag atgcagtaaa agacgcagat gcggtgctat tcgtcattcc aacgaaagca
    22321 atacgttctg ttgcaaaaga actagtgcct aaattgaata caaagccagt gatcatccat
    22381 gcaagtaaag gattagaaca gggaacacat aaaaggatct ctgacatctt gttagaggaa
    22441 atcccagcag aaaaaagaaa agctgttgtt gttctttctg gaccaagcca tgcagaagaa
    22501 gtagcaaaac atgacatcac tacgatcaca gctgcaagta cagatgcaaa agcagcaaaa
    22561 tatgtacaag agctgttcat gaataattat tttcggatct ataccaatcc tgatgtgatc
    22621 ggtgtagaga tgggggcagc tttgaaaaat attattgcta ttggtgctgg cgctattcac
    22681 ggcttagggt ttggcgataa tgcaaaggca gcaatcatga cgcgcggatt agctgagatc
    22741 agccgtttag gtgtagcaat gggtgccaac ccgctgacct ttatcggatt aagcggaata
    22801 ggcgatctag tcgttacttg cacaagtgtt cattctagga actggcgcgc aggcaacttg
    22861 ttaggacaag ggcagcccct agaagaggtg ctagccaata tgggaatggt cgttgaaggt
    22921 gtgaatacta cccaagcagc gatggaacta gcccaaatga tggaaatcga aatgcccatc
    22981 actcaaacaa tctatgaagt gctgtatgaa caaaaagaaa tcaaaacagc cgcaaaagaa
    23041 atcatgttac gtgatggaaa aaaagaaaat gaattctcat taacaatttt ttgaaggagc
    23101 gaatgtatat gaaagttaaa aaagcagtta ttccagcagc aggattagga acaagatttt
    23161 taccagcaac aaaagctatg gcaaaggaaa tgttgccaat tgttgataaa ccaacaatcc
    23221 agttcatcgt tgaagaagcg ttgaaatcag gtatcgaaga catcttgatc gttacaggaa
    23281 aagctaaacg accaatcgaa gatcactttg attcaaatat tgaattagaa acaaacctaa
    23341 gtgaaaaagg aaagaccgaa ttattgaaat tagtagaaga aacgacagat gtcaacttgc
    23401 atttcatccg tcaatctcat ccaaagggtt taggacatgc cgttcttcaa gcaagagcct
    23461 ttattggaaa tgaaccattt gtcgttatgc taggcgatga tataatggaa gacgaagtac
    23521 cattgacaca gcaattgatc gatgactatg agcgtacaca cgcttctacg attgccgtta
    23581 tgcaagttcc tcacgatgaa acttcaaaat acggaatcat caacccaggg gaagtactgg
    23641 aagatgggtt atacaatgtc aaaaactttg ttgaaaaacc agatccaagc aaagcaccaa
    23701 gtgatttagc tattattggg cgttacttat tgactccaga aatctttgat gtattatcag
    23761 aacaacaacc aggtgctgga aatgagatcc aactaactga cgcaatcgat acgttgaata
    23821 aaacacaacg cgtatttgcc cgtaaattca caggtaaacg ttatgacgtt ggtgacaaat
    23881 ttggttttat gaaaacaagt attgaatatg gtctgacaca tccagaagta ggggcacctt
    23941 tgcgtgaata catcatgtct ttaggtaaaa cattagaagc agaaggaagc aagatcaatc
    24001 ataatccaaa aggaataaca gaaatcaaag aagaaaagaa aaaataatct ttttttctaa
    24061 cgagcttcag ctgctaattg aataaaaagt agttgaagct cgtttttatt tgtttaaaaa
    24121 acacgaaaat gctatcctta tagaaaagag agacaagaag ggagtttgat catgtcagga
    24181 ggagaaattg caggattgat cgcagcaatc gcctttgcga tacttgtcgt tttcatcgtt
    24241 cgcgtattgt tgcaagtttc caaaacttta gaaaaagtag accagactgt cgcagaagca
    24301 aatacgacaa ttgagatcgt cacacaagac gtagatcttt tatctagaca agtagaaggc
    24361 ttgctagtca aaagtaatga gctgctcttg gatatcaatg gaaaagtcgc aacgatcgat
    24421 ccattgttca cagcagttgc tgatttaagt gaaagtgtat cggaacttaa tcattctagt
    24481 aaaaacatcg tgacgaaagt cggcggaatc ggaaaaacga cagctaaagc gactgttgcc
    24541 ggaaaagtcg gtggaacagc gatgaaattt tttaaaaaca aaaaacatac tgaaacgaca
    24601 ggaggaaaat aagaatggct aaaaaaggtg gatttttatt aggtgcagta gttggaggta
    24661 cagccgcagc aatcgccgca ttattgttag cacccaaatc tggtaaagaa cttcgggatg
    24721 aattggctgc tcaagcagat gatttgatgg acatggcttc agattacaca gatatggcaa
    24781 aagaaaaatc atctgagtta acaggtattg caaaagaaaa agcgcaaggt ctttctcaac
    24841 aagcagggga tctagcaggc aatgttaagc agaaggtaag tgaatcagca gaggaagcag
    24901 gaagtgaatc agatgatatc ttgttaaacc tcaaagaaca atcagctgat ttatctaatc
    24961 gtttcaaaaa aacagcagaa gatctgaaaa agccagcaga cgaattaggt agtattgcta
    25021 aagatacttc agaagatatc atgatcgatg taaaagatgc tgcagataaa gcaggagaga
    25081 cggtcaatga aggaatgtca gaagcaaaac cagttgcaga tgacacaaaa gaaatgttga
    25141 aaatggcaaa agaagatgca aaagaagcta aaaaagaaat gaaagataca atgacagatt
    25201 cgactaccaa tcactaagat tactcatttc tagaataaaa aaggtgagag cggaccagct
    25261 ctcacctttt ttattttcat tactctaaaa caagtaattc ttttggtgta gtcgtgaatg
    25321 gcacacaacc atcacttgtc acatacacac aatcttcgat acgtacccct actttttcag
    25381 gaatatagat tcctggttca agagagaagc acatcccttc ttcaatcact aagtcgtttc
    25441 cttctacaag agaagggaat tcgtggacgg ttgttccgat tccgtgacct aaacggtgat
    25501 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    25561 ctgctgtcac acctgggcga actgcctctt gtgcggcaag ctgtgcttca agagtgatgt
    25621 tatagatttt ttcttggaac tcagttggtt tttgataagc aactgtacga gtagcatcac
    25681 tgcaatagcc attccaaata acgccaagat cgaataacac tagttcattt ggtgaaacct
    25741 tcgtgcttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    25801 cgaaagacat ttgtgaaaca ccttgttttt ttaattggta ttcgatttct gcgataattg
    25861 cttgttcagt tacgccttct tttactgttt tgaagccaat ttcaaaggca acatcggccc
    25921 atttaccagc ttcgatcagt ttgtcttttt cttctaccgt tttgatcagt tgcagacgct
    25981 ggataataga agttagatcg gtgtaagaat ctgtacctgt caagatatca gagatagcat
    26041 cgaagcgatc gacagtcaga gcattctttt caatacctac attaccaggt tgcccatagc
    26101 gtgcgcgaag ctcttttccg atgatctccc aaggattttc gctgtctaag tagccacgta
    26161 catcgtacgc ccagctgctg ttttgagcat cttcaacttc cagagcagga gtgaaaagga
    26221 aaggatcttg ttccagaggg ataaaaagag ctagtacacg ctcgtgagga tcactttcat
    26281 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattct acttggtgtt
    26341 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    26401 aaattaattt tgtattcaat aattgtacca ctgattgatt aaaagaccaa cgttcttaaa
    26461 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tgttgagatt
    26521 atttgatatc ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    26581 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    26641 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    26701 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaatgc agtcgcacgt
    26761 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca ttcctgatgt cagcaatatg
    26821 ttctttgcct ctttagcacg tggtatcgac gatgtggcaa caatgtacaa atacaatatc
    26881 atcttagcaa actcagatgg caacgatcaa aaagaagtca atgtattgaa taatttattg
    26941 gctaagcaag tggacggcgt gatctttatg ggtcaccata tcacagacga aatccgtgga
    27001 gaattttcac gttcaaaaac gcctgttgta ctagctggtt ccattgatcc agatgaacaa
    27061 gtaggtagcg taaacattga ttatgtgtca gcaacaaaag atgcagtaaa taaattagca
    27121 aaaagcggca ataaaaaaat cgcttttgtc agcggtgcgc tgattgatcc tatcaatggt
    27181 caaaaccgtc taaaaggcta taaagaagca ttaagcgaaa acaatctacc atatagcgaa
    27241 ggattgattt ttgaggcaca atacaacttt aaagatggtc tgtctctagt tgaccggatc
    27301 cataatagcg gtgcaacagc tgtctatgtt tcagacgatg aattagccat tggtatcttg
    27361 gatggtttat tagaccgcgg cgtaaaagta ccagaagaat tcgaaatcat cacaagcaac
    27421 aattctttac tgacagaagt agctcgtcct cgtttgacaa gtatcacaca accattatac
    27481 gatttaggag cggtatccat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    27541 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatcaactaa ataataaaag
    27601 atcaatcatt taaaggttgt tccaaaagtg gtcaacttct ggaacaacgt ttatacgaga
    27661 aagggggtta tgacaaaatt ttgtcataac cccttttttt ttgtgacttt aaaaaaagag
    27721 aaaatggcgg aaacaaacct tacgtccatc gtatacgaca caatctgtgc gtagatgcta
    27781 cattttgttc actactatca aaattacttt aaaatgaaaa cgtgataaaa aagaaagtag
    27841 aaaagtagat aagtaactct aaaaaatcca aaaaaatcca ggctcgattg cgtacttatc
    27901 ttaaaggaga aacaatccat catatataac ccgaaaggag acttctattt gcctaagaaa
    27961 agacgaaaga ccatagtcat cattttgacc attcttacta taggaatcgg agggaaattt
    28021 tacatggaca aaagagaaat gcaaagacag aaagatttac tcgcagtaga aaaacagtcc
    28081 gtcaaagttc tgaaaaatac ctttgcggat atcaaggaag tgaagattga aaaatctgct
    28141 cgaaatgaaa tgacgggttc ataccggata gttattctaa tgactaataa acaagatcaa
    28201 tcgatttatt tttcttatag tttttggaaa gaaagaaatg agataggaag ttacggaata
    28261 gttgatgaaa aaaagcaaaa agaaggaaat acgctcaata aagttaaagt aacttactct
    28321 aatggaaatg aggaaagtat ttaatgatta ctgacaaaca atatagtgaa ttaagtgatg
    28381 ctgtttactg gctagatcct aaacatagag actatgtacc tgaaatgcaa gaaaatttaa
    28441 gttttaaaat taacggcact atgtataaaa tcctaaaaat caaaaactcc ttcgacggca
    28501 tgcaggcgat ggctgtagcg ccaatcgtcc atagcaaatt ggagaaaaat ttcaaaaata
    28561 aaaaaattcc tgcaaacttt cgcgtactta aataatgaag gtgtcaatac ttacataaaa
    28621 agaaaggagg cacgttcttg tcaaggaaaa taagaaaact cagcttagcc attttattaa
    28681 tcgtcatatt agggatcgga gggaaagtct atatggacaa aagagaagca caaaggcaga
    28741 aagatttact cgcagtagaa aaacagtcag tcaaagttct gaaaaatacc tttgcggata
    28801 tcagggaagt gaaggtagaa gaatttaaaa aaaaccctgt taccggaagt tatggtgcac
    28861 ttgtgacaat gacaaataat gaagggaaat ctgtttattt tgattatagt ttttggaagg
    28921 agagaaatga acttggtggt tttggcattg agaacagagc ggtacaaaag acaggagtca
    28981 ctataaaaag agtaaaagta attttttcta acggacagga ggagttagta tgacaataaa
    29041 cgataagcat tacaatgata ttagtgagaa ggtttattgg ctagatccca aatatccccg
    29101 ctacaatgag ggatacaaaa agaactctgt taaagaattt gctggtatgg aatttcaaat
    29161 cctacaaatc aaagactcat tggacggcat gcaggcgatg tctgtagcgc caatcaagaa
    29221 cggtaaagtg gatctttctc aagtagtgat tgcttttgca ggaacgaact taagtgattg
    29281 gaaagatttg gaaacggatg caagaagtat catgaatctc tacgggaata gaccaggagc
    29341 aagtttttct gaaaaagcaa caacaaacaa gattttatcc gttagtggat tgaaaacagc
    29401 ggggcaaatc aattcagcga ttgcatttgc taatgaagta aaaaaggaat atggagaagc
    29461 tgctatttct actaccggcc attcattagg tggattctta gcattatatg tagcagcaga
    29521 gaaacaatgg aaaaatgtcg gcttcaacgg gccggacccg tatgatctct tatcaccaga
    29581 agcaaaaaaa tgggtggaag aaaatcccgg tatgctcacc aattaccgaa atcacgccga
    29641 ttttatcggt aattttggtg gtaatggcac aggtgctgaa gttcggatca gtatggaaac
    29701 agcattcttg aatctgcttg cttcccacag tttaacctct tggaagtttg atgaaaatgg
    29761 aaagctgatt attcctgaaa atgaaaacaa tgttaaagct cgaaaacaac agaaagaaaa
    29821 ccaagcgacc cagttgtttt cctatcagtt gcaagaactg aacaacatac gtaaaaaact
    29881 acgattaagt ggcggccagc tgacagttaa tgaacaaatt tacttagatg acacacaagc
    29941 taggttagta gtggaaaagt tatcggcaaa aatgaaaagc gctatggaag aagttatccg
    30001 catcaatcaa agaggaattt ttgagctaga gaaaaaatgg caagaaggct tgcggcaagc
    30061 acgtgttgta gccccttcgt tgactgaaca ggaaatcata gaagcattag ctagtgtggg
    30121 cgccacaaaa gaaaacttag tcgattctgc gaaagaagtc tatctgctac gaatcaataa
    30181 ggcaagacgt atgggggagg cctttgatac attggcgaag gagatccaag acaaaatcaa
    30241 tgaaatcgtg gcacgagatc gagaattagc acagcaattc aattaaagga gaagtagatg
    30301 aaactagaag aattggaaag agattatcga agtgaacgaa gacaattaga agctcaagaa
    30361 gatgaattga tccactttaa gaatcaagga ttacgattga tggagcaaga ggagcagcga
    30421 ctgcatcatg tattaaagaa cttagcttta gataatgagc ctctgtttca agcaagacga
    30481 agttattcga attatcagga gcattatcaa caagccctac aagtagaacg acgaaaactc
    30541 tatcagcagc aagatgaact agaacgttcc tatcgtcaaa aaatcagaca aataactatg
    30601 gagaaatcat cttatgaatg aatttttaat gcaattacta aaagaattag agaaaaatct
    30661 acatcgatca aatgtacgtt cagttggtat ggggatatct cagcaaattt gggcagaaaa
    30721 acgattgaca gatcaaaact accaaatgac tgcagaagaa gctgctcaag aattttctaa
    30781 ccgacatgta cacttgaaag gatcagtaaa agggcaattt gcagaaaaac taactgaatt
    30841 attccaaaga caagaaaaga aattaaaaca gtttcgttag taaagttata tagaaaaatt
    30901 ttgtgaaaat ggtt
//
LOCUS       DAFEML010000027        30770 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFEML010000027
VERSION     DAFEML010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.027"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..188)
                     /locus_tag="LP468_001417"
     CDS             complement(<1..188)
                     /locus_tag="LP468_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080961.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGDI
                     LTLNLTTKTFVDAAEDYP"
     gene            complement(444..2036)
                     /locus_tag="LP468_001418"
     CDS             complement(444..2036)
                     /locus_tag="LP468_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080962.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQNSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQIEQERQ"
     gene            complement(2056..2478)
                     /locus_tag="LP468_001419"
     CDS             complement(2056..2478)
                     /locus_tag="LP468_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080963.1"
                     /translation="MVKAIEKHITFYEAHDEVLKHIMETQPTVKNYSEAIRFLCMNYD
                     PEIEKNNNMTNAKLNAMGKEISILIEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            complement(2496..2783)
                     /locus_tag="LP468_001420"
     CDS             complement(2496..2783)
                     /locus_tag="LP468_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080964.1"
                     /translation="MEIKEIKVRGINKKYVQEIDHRCVELTEQTGQKWSRNDYLKLLI
                     ENDFERPLMDYKKDQFDRLLEKFTDVQLHNTKVLEAYTNEVKNLIEILIAH"
     gene            complement(3240..3470)
                     /locus_tag="LP468_001421"
     CDS             complement(3240..3470)
                     /locus_tag="LP468_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080965.1"
                     /translation="MKRANLVGKDTFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKFRSFEALYVAAKKYFTAERK"
     gene            complement(3493..4299)
                     /locus_tag="LP468_001422"
     CDS             complement(3493..4299)
                     /locus_tag="LP468_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080966.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFSIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAINAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPHDLIFYVH
                     EDKVKDQVKDDNYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKENI"
     gene            complement(4310..4954)
                     /locus_tag="LP468_001423"
     CDS             complement(4310..4954)
                     /locus_tag="LP468_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080967.1"
                     /translation="MENKTLKIVLTAALSISLIGNIALFWQLKEEQATNTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTDAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAETS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            complement(4970..6172)
                     /locus_tag="LP468_001424"
     CDS             complement(4970..6172)
                     /locus_tag="LP468_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2080968.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNDNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDPL
                     PFLNSSKK"
     gene            complement(6246..6581)
                     /locus_tag="LP468_001425"
     CDS             complement(6246..6581)
                     /locus_tag="LP468_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2080969.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            complement(6581..6844)
                     /locus_tag="LP468_001426"
     CDS             complement(6581..6844)
                     /locus_tag="LP468_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HBL2080970.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            complement(6903..7280)
                     /locus_tag="LP468_001427"
                     /pseudo
     CDS             complement(6903..7280)
                     /locus_tag="LP468_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            complement(7411..9288)
                     /gene="ltrA"
                     /locus_tag="LP468_001428"
     CDS             complement(7411..9288)
                     /gene="ltrA"
                     /locus_tag="LP468_001428"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2080971.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            complement(9976..11670)
                     /locus_tag="LP468_001429"
     CDS             complement(9976..11670)
                     /locus_tag="LP468_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL2080972.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            complement(11833..12426)
                     /locus_tag="LP468_001430"
     CDS             complement(11833..12426)
                     /locus_tag="LP468_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080973.1"
                     /translation="MRVKGQNSVDKKSIFQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(12427..12759)
                     /locus_tag="LP468_001431"
     CDS             complement(12427..12759)
                     /locus_tag="LP468_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080974.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(12811..15189)
                     /locus_tag="LP468_001432"
     CDS             complement(12811..15189)
                     /locus_tag="LP468_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080975.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSSLSDLQKDRLRALQYRLELDDNGKEVPVQISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNI
                     NSENEKRISDLPKRNQEVQTDDDSIDLPNDNGVEVGTEKSTKIGLPKAQNLPMKDSRL
                     NQFKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREA
                     APEPIQRVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLRDIKQDIKP"
     gene            complement(15186..17798)
                     /locus_tag="LP468_001433"
     CDS             complement(15186..17798)
                     /locus_tag="LP468_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL2080976.1"
                     /translation="MRIRETTKRKDKPFNLEKKKYLSHFYRYVPAGERLPGKHDKRVK
                     QKLMYSGLVYLPLDYLVTRIPEAFSRFEIIQGSLQGVNLFQLQEMPQVFHFDSAGFWN
                     PLTPATSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPDTKGSFPGYGGIPITHYKKYWYIQTDTVNTCIIGTSRSGKGQIEVLATIDNLSRAE
                     KQSSLVVNDPKNELYVASKDELEARGYDVYAYNLTEPLQSMSDNPLALIVKYWQRGDV
                     DTATQLANTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYTKLTPNN
                     LVELLSEIGGFNYQDPTNEFKQLNALDEFMNQLPPGNLAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRIGVEFYHDGKK
                     FHEERVKVGYKEFCEINFDCHLEQGDQVCLKYDHQGKEYVAWYEFSQKVLKDEKGNIV
                     YRKKRGETHLPEWEKEAVLTLDESKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYKQLRAKYGEDNADIIKENCQTHIYIMSSNTDTIEEFSQNVGNKTVEQENST
                     INALGMNTHINRNVDSDRILPPERIRSLLKGETIVLAPLKREDLKGNKIRPYPIFNSE
                     KTNSPYAYQYLEDFDTLGRTIHDIDIYCTHADLDLKALQIDYDYFLPDEDARDLYHGL
                     HEQLEEKIEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNEEISEII
                     GKRLLLEADKAVRE"
     gene            complement(17798..19855)
                     /locus_tag="LP468_001434"
     CDS             complement(17798..19855)
                     /locus_tag="LP468_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080977.1"
                     /translation="MYFTIAGNTKKDKELIKKATKEVGKRTSFLPKTMKYSVIETEEQ
                     LHVLGKVLEQESQSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     DESKEKETDNVDEQADIPTQKSIFEEENEVMDQLDGDPFEETMEETTEVEIDPVEANE
                     EPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNQLFLNE
                     LYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEERQQ
                     ETDQEINEYAAEQSSNWEKAKEELNKEEQQVIEEEVQKIKERYEKKRDNAYSLCVEKI
                     NNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTTTE
                     VLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQDLA
                     EQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQLQPMPSVAAVQTPMNN
                     QTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQ
                     EQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKTKEGSSDSTVQSNSSESSESN
                     EVK"
     gene            complement(19924..20226)
                     /locus_tag="LP468_001435"
     CDS             complement(19924..20226)
                     /locus_tag="LP468_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080978.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAGVAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGIILAAASIVVSLFGMFGQTPQGL"
     gene            complement(20244..20444)
                     /locus_tag="LP468_001436"
     CDS             complement(20244..20444)
                     /locus_tag="LP468_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL2080979.1"
                     /translation="MAKAKTPFEKAASKILERRGVSETQWKQEVLEKAQFDLLRGKDK
                     DLEGYIYQREREKLVFDEIIKH"
     gene            complement(20484..20951)
                     /locus_tag="LP468_001437"
     CDS             complement(20484..20951)
                     /locus_tag="LP468_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080980.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLVNNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGISDFI
                     NKPDSLFIVVPYEKDGVKKMVFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            21140..21346
                     /locus_tag="LP468_001438"
     CDS             21140..21346
                     /locus_tag="LP468_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080981.1"
                     /translation="MYADKNEIEWLLFESGISVKDIYMESGVARTTVIDLINKTSSID
                     KMRFDNAVKLTKMAKMRKNLYENK"
     gene            21486..23552
                     /locus_tag="LP468_001439"
     CDS             21486..23552
                     /locus_tag="LP468_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBL2080982.1"
                     /translation="MKLLNPKTVIAGTFAVTLAATLSLAGSVDAASTSVMYRLYNPNN
                     HEHFYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEV
                     KWLTKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWK
                     YEGIGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDS
                     KATQKQVDSAKNTLDSAYKGLKKKPAPTVNKAELQALYNRLKSTAKGDFTEESWNNFQ
                     TALSNAKKILDDSKASQAQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLL
                     KEEHVSVKAGTSYTAKAKTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVE
                     VKARPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPTFTNFVLDPRESSSNTVTLN
                     NVTSNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDNFSTSWKNMTDQNYFL
                     CRNDDSSVTVDKNGQRIINHVDQNRTITFKYKNISLNDLNNYVRQKELAWLNSYRQQN
                     GVAPMQFNDVVQKAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYL
                     YVDEILSDTGAVNAMIMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFIS
                     ANPIFK"
     gene            complement(23588..25678)
                     /locus_tag="LP468_001440"
     CDS             complement(23588..25678)
                     /locus_tag="LP468_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2080983.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVSGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNIL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHATQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVECGSNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASANFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTTLVVSLLL
                     LVLATFSYVVLKFN"
     gene            complement(25675..25935)
                     /locus_tag="LP468_001441"
     CDS             complement(25675..25935)
                     /locus_tag="LP468_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080984.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQPYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVVVGISLVIYKKEGMKG"
     gene            complement(25948..26709)
                     /locus_tag="LP468_001442"
     CDS             complement(25948..26709)
                     /locus_tag="LP468_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080985.1"
                     /translation="MRNRKWLFVCAAALLSFTAYTQLTFADSQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKNLTTDQIESQLKDRVKKLSSDQLKLVSNGETKTIGQQT
                     GVFEFSVEVQANQKQAYYIVNETSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            complement(26725..27477)
                     /locus_tag="LP468_001443"
     CDS             complement(26725..27477)
                     /locus_tag="LP468_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2080986.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAAGVLLLMPAEASVAKYQQNQ
                     QIVAIDRTGTAAETDSSLDVAKIELGDSVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEKN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            complement(27492..29468)
                     /locus_tag="LP468_001444"
     CDS             complement(27492..29468)
                     /locus_tag="LP468_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2080987.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVTSETSPYSVFKWGDTA
                     GQGLSFVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYFGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            complement(29521..30192)
                     /locus_tag="LP468_001445"
     CDS             complement(29521..30192)
                     /locus_tag="LP468_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2080988.1"
                     /translation="MKKWLFVFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(30252..30461)
                     /locus_tag="LP468_001446"
     CDS             complement(30252..30461)
                     /locus_tag="LP468_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080989.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(30528..30767)
                     /locus_tag="LP468_001447"
     CDS             complement(30528..30767)
                     /locus_tag="LP468_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080990.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT         8387 a         6322 c         4836 g        11225 t
ORIGIN      
        1 aatggataat cttctgccgc atcgacgaac gtcttcgtag tcagatttaa cgttaaaata
       61 tcgccatttt gatacgcttt tgccgctttg tctgtgacga caaaagctct gcctgtttga
      121 atttctgtca caaaaacgag attgtctctg cttttttcaa caacaactcc aatcgttgaa
      181 taagccattt cttcttcctc ccttctcttt cttttgatat aatgtagtcg caaatcgcac
      241 cactcattga attggcggaa aacaattcat tgaaaaaaag agtcctggac aattacgttc
      301 aggactcttt tacttctttt attcacttaa caactaacat tctgtgagtg aaatagactc
      361 ttcaatgctt ttacacggga agttattgat cccctcttca ttcatttccc aagtagtata
      421 ataaggcgct aactttactg tctttactgt ctttcttgtt ctatttggat tcttcgttgt
      481 tgctcttcgt aggctttact tgcgtggtat ttttcttcat gggcattaat cgttcgattt
      541 aattgacgca aactccgttg cgtgacaact ctttgttgga attgtttcct gcgcttcatg
      601 aattcttcgt aactatattt gtattcattc gttggtaact gtttaagcgt tcgaaaggat
      661 cgttcattgt aaatagattg catctgatcc atactttcta ttaaaggttt tatttgacta
      721 ttctgtttct tcagttctgt tagaatggca tttcctgtgc gctttttcaa atcaaagaga
      781 gcattttttt ctgcatcctt tgattctctt ttgctttccc cataaagact ttttgcttct
      841 tctttcaatg cttttgaaat ctgtatatat tcttgatatt caggttcttt tgttaaaaca
      901 tatttggtta actcatcgag tttctctctt gtgtatggtg aaagtttggt tcgtttttca
      961 tccccataat gccattccga acgtttgtca ggtagggttt tatatacttc atttaataag
     1021 ttcattgcgt gtcgatcgta acgcgctggc tcttttacca cttttgttaa ggtgttacgc
     1081 aaatcacttt tccgcgtcaa taaatttcgt ttctccatac caatcattcg atccttttca
     1141 taagaaaaac gttctaactc atgtacataa ttggtcttca ttgcgtctaa tgttgcttgt
     1201 cttctcttac ctttcggtac gatataactc acaccatttt caacctccgt gtaaggttta
     1261 cgcgtatttt ctttttcaac aactgcaaaa tgaatatgga tatgtttggt attacggtga
     1321 atcgttgcca tccagtagcc tgtttcgttc agttgctctt tctcgaataa tgtctccatc
     1381 atttttcttc cagctgcttt taatccttct tcatctaaag tatctgtttt gggatcgtac
     1441 aatcctattt tttcaagata cgaattatca tgagagacaa catcttgata aatgattgag
     1501 cctttttgtt gtcctctttg gaagatttgc ttaatctcct tcagatcact tcctttcact
     1561 tcgtctgaag ccatagaaaa aactccagga aggtttcctg aagctttttt gtgtggctct
     1621 gtttgatatt tttttattgc ttggttcaag cgttggtatt ctttttgttc actttgcgtc
     1681 agttctttct tttgttctaa cgcatagtga cgggtcatat aagaaagata tttggtaaaa
     1741 tcttgttcct ctaacttgtc aaagttgatt ccatttccca tcaaagattg agcttcattc
     1801 gacgtttcgc tgaattcttt atccgtctta ctctccgaaa aagtttctcc ttcaggaata
     1861 taaaaatcct ctaaagcatt cttgattcgt tgcagttcct gttcttcttc aggcgtacgt
     1921 cgttccattt cttccagcgc tttttctctt gtcatataat caatgtatgt tgaaaaagat
     1981 tttttattgg gcaaggtaaa ttgacaagtg agaatgactg caggcgattt attcatcata
     2041 ttccccttct actttttatc tttttaaaaa ctttgttgga tcaaacgggt ctactctggc
     2101 atgaacagat tcatttattg atttcttgat tttaggagaa tacttcttcg tttgattcgc
     2161 ttttattttc ccttccacac gctcttttgc ttcttgatag acagttgaat ttgtaccaat
     2221 taatattcct gtatctttca aatgaagatc cgcaaactct gaaaccattt ctattaaaat
     2281 agaaatttcc tttcccattg cgttcaactt tgcgttcgtc atattattat ttttttcaat
     2341 ttctggatcg taattcatac ataaaaatcg aatggcttca gaatagtttt ttaccgtagg
     2401 ctgagtttcc ataatatgtt ttaaaacttc atcgtgcgct tcataaaatg taatatgctt
     2461 ttctatcgct ttaaccatag aacattatct ccttcctaat gtgcgattaa tatttcaatt
     2521 aagttcttga cctcgttcgt gtatgcttcc aaaacttttg tattatgcag ctgaacatct
     2581 gtaaattttt ccaataaacg atcaaattga tctttcttgt agtccattaa aggacgttca
     2641 aagtcgtttt caatcaatag ttttagataa tcatttcgac tccatttttg accagtttgt
     2701 tctgttaatt ctacgcatct atgatcaatt tcttgaacat attttttatt aatacctctt
     2761 actttaatct ctttaatttc cattttcacc ctccgaaaaa agtatggata gtctatggag
     2821 tctatccata tgctatccat gtatagctgt tttactatcc atacactatc cataaatcga
     2881 atattttgta cccacttttg ttttagagaa acgtaatagg cacagcctat tggaacactt
     2941 tttttaaaaa gtgttcccac gtttccttat gctctttaaa aattaaggtt atttgtgtat
     3001 ttagacaata aaaaatcctt ctaactttgt cgattagaag gaaatatttt gtcatatgaa
     3061 aaatgaattt aagaaaaagt gtatgctata attgatacgc tgtcttcctg tttggttgaa
     3121 atcttcagcc agaaaggagg agtgttaaat gttttatgtg cttgatgttt gtgttacggt
     3181 gatatagctg atccataaac atttttgata tacttttttc acataaaatc ctcctgtttt
     3241 tatttccttt cagccgtaaa atatttttta gcagctacat atagagcttc aaacgatctg
     3301 aattttaagg tatctaaact ctttctacca ttcttcaact cagatattgt tgtgttagat
     3361 aaattcactt cttgacatat ttctttagct tttacaactt tgagataggc tttaatcaat
     3421 actttctgct cagcgaaagt atctttgccg accaagttcg ctcgcttcat ttcttttact
     3481 ccacctattc ttctaaatat tttcttttgt catacgatca attttttctt gaagtttttg
     3541 aatgatctct tcttgatctt tcatttgcgt tttcgatgtt tcaatttctt gctggtaact
     3601 attaatctta ttttcagtat tttcctgatc gtctgcaact tgataaggca attgatcttt
     3661 tagtttcttc actaattctt cattcaaatc aatggttgct tggaaggatt caatttgttt
     3721 ttgtgctgct ttttgttctt tcttgtatcc tttcactttg taattgatcg catgttgttc
     3781 ataattatca tctttcactt gatctttaac cttatcttcg tgaacataaa agatcagatc
     3841 atgtggttct tgcatatcca cttttggatc aattttttca ggaataatgg ttaaacgcat
     3901 ggcgatatat tcttctggta catgtgctaa cttcactaca aaataatcat cagacacctt
     3961 gatcactttg gcatttattg cttggtaatc ccctttagct gtctttactt ctacacgata
     4021 attaagatta gccagttctt ttaataagct ttgatcttca tcgtcgatcg aaaattcaaa
     4081 aactaattgc tggttcgctc ctttttcttt tgaaaccatc gtcagttcct tcgtgtttaa
     4141 aaatgcgttt gtacttacct catctggtat gtctactttc tgatgcgtgt aaatcggact
     4201 agcaagaatc aaaaagccga gaatcataaa gattcccagc catctaagat aactttttcg
     4261 ttttttgaaa cgttgtcttt ctcctttttt cttactcatt ttcttcctcc taacgagtga
     4321 aataactaaa gtcagtgact ttccattgac catctacctg tttttcagtg acagttaatc
     4381 caccttttat tttttgtggt ttgacatctt tgaattgagg attgccaatt gtataatcaa
     4441 caaatacgac aaaattttgt tcctctttta cactgcttgt ttcagcgtaa gtttgcacgt
     4501 cacctaatgt aaaggagtaa cttccataat catcatgttg gtgatcatca tctgcaggac
     4561 ttaatttgtc gatcacttct tgggttgcga catcttttag tttttccgtt aattcatttc
     4621 tgcttagtga tttatcaatg gccaattgac cgaactcttc tgccgtcttt ctttgggcat
     4681 ctgtgacttc ttcttttgct tttgtaccgt cttgttgctt cagctgatcg atttcttggt
     4741 ttttctcatt gatggtttga tttaacttgt cgatcttcgc ctgtgcctca gaggaatttt
     4801 ttttgagctt ctcagacgcg tttttagcca cttcttcaat tttataggta tttgtcgctt
     4861 gttcctcttt cagctgccaa aagagcgcga tattgccaat taagctaatg ctgagtgcag
     4921 ctgttaagac gatttttaac gttttatttt ccatattttt tctcctgatc tattttttgc
     4981 tgctattcaa aaatggtaat ggatcgatcc atgtaccatc atctgtgaat gcgtgtcctt
     5041 gtgcttgacg ccaatccatt cgagtgaagc ctaaatgcaa gtgtgctgta tctcgtatcc
     5101 cgattacttg accaactttc acttgatctc ccactttcac acgggaattt cctgtactat
     5161 ttgcaaattc ttgatatacc atattcaagc cgtcgtaatt aatcacgatc acacacgcgc
     5221 ccaaacctga aataccagga tttccaacgt acacgacttt tcctccatga accgcatgaa
     5281 tctcacttcc tggatgatca actgaaccaa agtctaatcc atcatggaaa ccattcggac
     5341 ggaattcacc gcctggattc gttccaaata attgaccacc gctgaaggaa cttttatcta
     5401 aactgctgcc agggaaagga ttcgtccatt caccagtaat cgtaccgttg tcatttccgc
     5461 cttctcccca atgtttgatc gcaaattcat catattctgt taatttattt gaggtaataa
     5521 tcgacataca acctgtataa tacggactat cttcagtaat tcctgcagcg gcataaccgc
     5581 ctcgtcctaa gatcaataag cttgcaccag ggcttttatt tcctacacat gcattaaaat
     5641 ttgattgtgt ggctaccata aagccgtaat aggagaatgc agcttttgag ttgggaaact
     5701 tcatgtacca gcccccttca atgccaccaa ttcctcgtgc agttccttta ggaaacagac
     5761 aaccatcaaa ccaagtaatc ccaaaatagt tgagatcatt tcttgcggac gccgacgtac
     5821 caaacgctga ttcataaccg tattgcgaaa gaatcacact tggtaataat ttatatttca
     5881 ctgctgcacc tacggcatat tgcgcaatct catcagaaaa agggcctctt cctttgattt
     5941 ctttataaat cggtaagcct tccgaatact ctcctgtaaa agcttcgcca ccactacttg
     6001 aatcggaatc cgaattatca atcgaacccg ccgcaagtat tagaaaaagg gttacgaaca
     6061 cagtgatcaa aatagtaatc aaacctgcag aagtaccaaa caaccacaaa aataagcgtc
     6121 gctttgcacg acgcttcaaa tgttccataa ctatatttgt atcattttcc atatagtcag
     6181 tactcctaac tttttaattt taaacaacaa aaaagcgaag aaataataat tattcttcgc
     6241 tgcttttaat aaaataattt aattttttca atacattctt ctaaaatttc ctttggcaca
     6301 gcttccacaa actgaaaacc tctactctca atgtcaatca ttcgatggtg ttccaaaaga
     6361 atttgtcctt ttattttttg cgtaccattc aaatcaacat gtacaggaaa aggcttcgct
     6421 tttgttgtta tcggtgcgac accaatcata tagttcaaat atttattagg tttagataaa
     6481 ataatacatg gtcgttttcc ccgttgttca tgtcctttgg taggatttaa atcaatataa
     6541 acaagatctc cttgcgataa atcatgatag ttctttttca ttaaatgatc tccctacctt
     6601 gcatatttcc ccattcatat ttgtcttctt ttcctaaggg ttctccttca taattggcga
     6661 acaattcatc taaagtttct ggctttttat ttttaggagt taaaacaatt tttccttctg
     6721 ttaccaccat ttcgaatttt aaattttcag tattagtttc tcctagaact gacaattctt
     6781 cttttccaaa acgaatacct tgtgaatttc cccatttttt catttcgatt tcttttacta
     6841 acatggaatc cctccttctc tcacacatta gtatatactt gtatacacca aaatacaaga
     6901 agttactttc caccatcaaa caatttcaat tgacgtttgt tcggactaaa atgaacacga
     6961 atggtttctt ttgagccaaa attgatcaca gcgtctcctt gattttgttg aggaatggat
     7021 tctagttctg agttcgtcat tgatttacca actaatcctt ctatatgacg taaaatagat
     7081 tcatccatac gcataaagat cttcgtagaa gaaaattcaa agactttctt cagtttcgag
     7141 aagttatcag aagacatatt ttctggcacc atttcttgtg gggattgtgt agctaaaaca
     7201 gtcattgctt ctactttacg catttctcgt tgaaagtttg tgacataatt taccgtttca
     7261 ataaaatctg gattaatcga tactgatagg taagagtttg atattatctc cgtcttttcc
     7321 cccagtccac accgtacgtg cgactttcac cgcatacggc gttccctcgt ctataaaaga
     7381 cattctgttt tcccgtccta caaatattta ttaagatatt tcttcgttac caacttttaa
     7441 tctcaactca ttgagttttt ctttttgttt tggatttaat tttagatatt ttagaagttc
     7501 ctcaatcgtt tcactttgtg tagcgtgtat tacccgatga acctcctcag taacaatcac
     7561 taggttttca tagctatcac ttttgctttc atgataaggg ataatatgat gacaatgcat
     7621 ttcagataag ataagctcct cacctgttac tgcacatctt cccttttgag cgatgaattt
     7681 tgaaattcga ttgtccgcaa attcaatcgt tgctctctta ctaagcactg gattgctaca
     7741 caaccacgat atcttccatt cttctacggt ttgttgcttc ttatgaatgg cttccctacc
     7801 ttcttcggtg tatttattaa tatttctttt tttacacatc ggatgtctgt gttgaatata
     7861 ccctactggt aatattggaa accctcttat atatcgtatt tgtcctgacc gtaggtaagg
     7921 cttgtatcct tcgtactttc cgtattgtcc ttcttttgag attccttgtt ctcgtagtcg
     7981 tatttcaaaa cttggtctga gttctcttgc aatttttcgc attgctacac tacaatgagt
     8041 cgcaattttg aagtaattat gaatcccaat aaccatactg ttatagactc caatatagat
     8101 aaaggtatct ttgctattag gacttttttg aattcgtttg atttgttttt ttagtttcac
     8161 tttaatcatg ctttgtgctt ttgtacctat atgcgtatta acaacctttt tgttaccttt
     8221 ggtcactaat ttcatcgtaa agcctaaaaa ttcactttct tcttttgaaa gatttgtgat
     8281 ttttgacttt tcttcagata ttggtaactt tagacgctcc tgtaaccaca ttttagttgc
     8341 atagaaaact tttttcgctt cattataatt tctacagaaa attttaaaat catctgcgta
     8401 tctcactagg tatatttctt ttagagttgt actctttctg agcttgtgat agatattacc
     8461 tttatcccaa gctccatttt tcctaaaatg atgttttagc tctttggcat ctttttcctc
     8521 ccactgattt gctatccacc agtcaaattc gttgagattg atgttcgcaa gtaatgggct
     8581 aagtattccg ccttgtggtg ttccttttgt tgggtatatc aacttcccat ttggaagtac
     8641 tacgggtgct cttaacattt tcctaatgat taagagaagc tgtttgtctc gtatacccat
     8701 agaccagatt tgtctcatga gtttagtatg attgacttcg tcgaagaaac ctttgatatc
     8761 tacatctacc acatattcca tgtgactttg attcattcgg gccatacaat ctgctattgc
     8821 gtgttctgct gatctatttg ggcggaaacc atagctgtga ttattgaatt ttgcttcaca
     8881 tattggttct aatacttgta agatgcattg ctgcgcgatt ctatcccata ttgatggaat
     8941 acccaacggt cttaatttac cattatattt aggaatttct acacgcctta ctttccgagg
     9001 gttataatgt gcgaatcgct tcctaacaat ttctacgaat tcattacggt tgagattttc
     9061 aatatcttta atcgttactc catcttctcc tcttgtcaca ctaccgtgat ttctcttgat
     9121 attacgatat gctaggacaa tgttgttatc agaaatgata atctgcatta gattcttgaa
     9181 attatctccc ttcaaacttt tggagtatat cttatcgaag atttccgtca tgccataata
     9241 ttctgcatgc cgcaacttcc tatcttttgg acttgtttct tttgtcatgg tttatcacgc
     9301 tccaattggc tcgtgacctt tttagtcata cgagaatccc atggttgaac gggtttcatg
     9361 acttttacag acgaatcgag cctgttcctc cagttccatt acagaacctt catcagtcgt
     9421 gactctactt tcaccatcac taaagtaagt tatttgtcat tcacatattt cttactacca
     9481 cttcatcgag tatgcactct ccatgttgat ggcttcccct gttcccttat atctatccac
     9541 atgccttaac ttagatgcta gcttttgccc cctaacttct cctacgcctg taacgcagca
     9601 tggtctttca taacaacgac ttttactcaa ccacaagtta gcacaatgag tgattttttg
     9661 ctcactgtct ctcccatttc taggagctat gcctttcgga cagtacattc gctagttcgt
     9721 cagtacgttt gtacatactc accatattaa gtttttttgg acacccgact tatcggatac
     9781 accctttacc tctaaagaac tttcgtggta ttcactattt cttttacctt acggtatcct
     9841 tcagccgact tcaccgagct tcacacaacg ttggtctgca taaactactt gttgcatgtc
     9901 ggagtatcag tggaagccct ttgtggcgtt acccactcat ttgacttctc gttataagag
     9961 ttattacaat agtttttaga ctacttgcaa cccacagctt ttcactgcag aacaggtcgc
    10021 accattatgg cactcatcaa tcatcgccaa gaagcgtttg aagtcttgtt cttccatttg
    10081 tttttcttta agtaaacgtc gttgtcttct tccttgaatc aatgcctgat tccaaatcaa
    10141 cgtcatagcc atgtacattt gacattgttg tacccctcga tctaagcctg taatagagtc
    10201 aatgtcaaaa aagaccaact gttgttggtc aaggtgtcga atcgtactgt gaccatcaaa
    10261 aatcatgcca tacgtctcac ataaggattc tacgatggat tccatttctt cttttcgatt
    10321 ctttttctct tgggaagcac ctggtaattc cagttgtcct aaaaagtcta aaaattcttt
    10381 gaacgtcgga taagcttctg gatctttccc tgtgacttgc gtctccgtat ttgaacgcga
    10441 atttgaggaa gtaaagccgc gtggtactgt tccatactct tcataaaaac gatttaagta
    10501 ggtcttaaat tctgctttca tcgttccttt tagctgagga ctcactaact gtacctgata
    10561 gaccactttg tctaagtgtg tttgatagga cgctgcttca ttgatcttca aatctttgac
    10621 tgatccatcg tcatataaac tggatgcttc atcatacgtc cgtgtggcaa atatctctaa
    10681 aggattgatc attccgtcag atccgtctaa acgcaccata ataccgttat attcctttaa
    10741 gaaaggaata aagtcttttc ccttttcaaa gccccaaata aagtctcctg cagctaaatg
    10801 ggcttccgcg atcattttaa gaacggtcga tttaccagct cccatcattc ctagaagcaa
    10861 ggtattagta gacaaccgta cactattttt atacgtcgca ttccagacaa atgggccgcc
    10921 tgtcatggtt tccccatatt gtgtccctcc tggatctttt agcgtttggt ggtggaacgg
    10981 gaaacctccg ccaatgttta acgatggtag tgattgccct ttgatatttc cgaaccattc
    11041 agcttgttca tcgaacatgg taaacatcga ttgccaatct cgtttggttt tatgcagata
    11101 agtcaccgca cgataatcca tccctttgag attttcgatc agttcctgcg ctcgttcatc
    11161 tacttcttga atcgtgtttc cgtaaacatg tactctcact ttgacttgct tagaaatttc
    11221 cccattagaa gtcaattttc tagcatattc cgctagttcc aggtattctt ccgcgctttt
    11281 atttcggtca gtcgcttttc gttcattatc tgatcgatca tttaattcat ctaaggcacg
    11341 attgatttga tcaatcactt tttgcttttc atctgtgcta acatcgagtg tggccactgt
    11401 atgaggattg ttcatgagat tggccaacca aaaaagcgta ggattttttg tgtagtgata
    11461 aactgtcaca catcgtgaat aaccattacc atacgtcaca tattcttcat caaaatttaa
    11521 cccaccttgt ggcatcactt gttttaaaaa atctaaatca taccctttgg attttaaaat
    11581 ttctatttcc cgatttccta gttgctttaa tggatcaagt actttttgat cattttgtgg
    11641 tgaaaaagct gttttaattg cttctaacat gtacagtcac ctcttcttgt ttgattcttt
    11701 acttggttaa aagattgccc ttttcccaac ttacccaggc ttaaagtgtg aggaaatttt
    11761 ctagtggtct cttccttcgg aacatctttt tctaaccata tcaacggata tttcattctc
    11821 tcttctccat tcctactcat cattcatatt gttcattcga tacagaatct tgatcaattc
    11881 ttttttgtag agtggtttta accctaaaat gccactagat cgcattaact gacggtttct
    11941 ggtttgtaaa tccttgattg tctttccttc aatgacgaaa aagaagctta agtcaggacg
    12001 ttcttgttct gctcgtttca attcctggat ttcctctact aatttctttt catattttct
    12061 taatcgctgt agatttcttc ctaaggattg ttccatacga ttcttatcta ataactgccg
    12121 cttttgtacg atttgttccg ttaaatccgt ctctgtggtc aaactaacta acttaattgt
    12181 tggcacatac gtacgcatga cggtggtcaa ctgattcatt cgttctagtt tctcttgttc
    12241 atttaatcct tccacgtctg tagaaactac acgataataa cgttgaaaat gatcttcttt
    12301 agtaactaag actccctctt ctgtacagga tttataagga aataaatcca agatagatcg
    12361 ttcttctggt tttccaaact gaaaaatgga tttcttatca actgaatttt gtcctttgac
    12421 tcgcatttat tcatcctcct tatacgtacc atgataattt cggttaggat ctaacgcatg
    12481 ataatggttc ttgtccgtaa aaaaaataga ctcgataatc gcaaaaattt gtcgttgacc
    12541 tgggttatta tagggtcgcc aaacaatcac tagagctatc gcaatccata agccataatt
    12601 caagagtgca aaaaagagtg gtaaatggac aaggttattg actattttcg cccaaaaaaa
    12661 gcaaccacca agcgttaata gatccaaaaa gaaaaaggca aaaaacttcc attccccact
    12721 aaatcttgga ggatttttca tgttaatata tttatccata aatgatttct ccttttcata
    12781 catagaaaaa aggcctaact tgtaggcctt ttatggtttg atatcctgtt tgatatccct
    12841 caatagttgt tctttcaatt cattgttcct gtttttagtt tctcttgtca catttatttt
    12901 tgttggtgca gtaaatgcca catttgctgg tttgtaacct gtgtgaactc tttgaatagg
    12961 ttctggtgca gcttctcttg tcacaacatt ttgaacggac gcattccctg tctccccact
    13021 ttcagataaa ttgtaagaaa cagttgtcag atttccattt tcaggcaaac gacttggttt
    13081 catttgaaca ttacctgcag ttgattggtg aacaaagctt tgatcattct ccttgaattg
    13141 attcaaacga ctatctttca ttggtaaatt ttgtgcctta ggtaaaccaa ttttcgttga
    13201 tttttcagtt ccaacttcga ccccattatc atttggcaga tcgatggaat catcatccgt
    13261 ttgtacttct tgatttcgtt ttggtaaatc tgaaatgcgc ttttcatttt cagaattaat
    13321 gttagattta taacgatatt gttctggatc tgtttttggt aattgaccat tttgtccttc
    13381 ttctgaattt tcgttagaat gcaactcatc ttggtgatct ttggctgaag gaatcgctgc
    13441 accttcttga ttttcttttt cggttgttgt attagctttt actgctgcat tgacttgtcc
    13501 ttcaccatac gcatctttta gtccttcttt gacttctgaa gctttttctt tttgtttttc
    13561 tagtgcttcg gatggattct tcacagcttc agccaattct ttagctctcg tgccgtctaa
    13621 tttctcttct aaggtgtctt tggctttttc tgtaagatct tcagctgttc cttttaaccc
    13681 acgttcattg acgtaaccaa gaccttctgc ggctttagaa acaccatttt tcgctttccc
    13741 gaacatttcg gaaactgttt tcttactatt aggtacagtt gtagctttat cgtctgattg
    13801 ttcttccccg ttatcagggg taacatcttt tcgatggcca aatccatttt tacgaatatc
    13861 atttaaatgg cttaaaccac tcttaccagc acttgcaagg tttttagctc cgctacccac
    13921 atttttcgca atatttccta aggcaaacat gctaagaaga gaattgctgc cgtttttcag
    13981 actcgtatcc acaccgaaaa ttttcgtaac tgattgagag cctttgaata acgcaatggt
    14041 tagtacaatt aaagcaacga catacaaaaa tccattgatt tttcctgccg catgcaaatc
    14101 accgatacct gaaagcatta atgtatagat tcgtaattct aaaatcgtaa acgccaataa
    14161 caagaaagac tgagaaatat cttctatagc acttttcatc cgttgtcctg tctcaaagtc
    14221 cgttgacgcg gcaatcacta aatagaattt tttaaatacc agctcaataa tgcaagtaac
    14281 gatcgtaaat aggataaata aataggctac cgacaaagaa gattcaccag ctaaaataat
    14341 ccctggacta ctaatgtatc gacgataccc tgaagtataa acatatttgg ctaagccttc
    14401 atcactgatt tgaacaggaa cttcttttcc attatcatcc agttccagtc ggtattgtaa
    14461 cgctcttaac cgatcctttt gtaaatctga taaactactc ttatctttat ccgccatttc
    14521 tttagcttgt ttaggagtaa taatcccatt gatattcgct gttttaaaat ttttcgctgt
    14581 taaagcattt cttttatctg ttggtaggga ttctacttta ttcgggtcag ttgctagtaa
    14641 tgtacttaca tcgatcacat tattttgaat aatttgaaaa gcaggtgaac ccgttttatc
    14701 tgctttattt gctgcagtga cgtctccata aaagttttta ctgatattta acccttcatc
    14761 gattaaagaa ctaccaccaa aaatcaagat catggccata aataaattaa ccaagatatt
    14821 tttgactttt ggtggatgtt tactcataaa aaatttcaag cctaaataaa ttaatgtgac
    14881 gacacaaaaa agagccaata ccttactaat caaactttga aacagttcat taacaccagc
    14941 ggcgttcaat aagtctttta aatcaaagct ttgataaatt gttttttcta gtaaagtatt
    15001 gagattatat aaccctttga tcaaccccca taaaaaagta ttacaaatcc aactgaacac
    15061 atcttgatac tgcagataat taccataatc ttgtaagact ttcgttacgg ttttgggatc
    15121 tgcatcccct tcaccaaata aacctgacca ccagtcggct atgccagaaa aaattcctcc
    15181 aatgatcatt ctctcaccgc cttatcagct tccaataaca accgtttccc aattatttca
    15241 gaaatttctt catttttgat caacttttca acatattctt gaagtcgatc tgctgcttgt
    15301 tcttcgtaaa attgaattaa caattttttt gccgtctcat tttcaagaga ttgaacaatt
    15361 ttataaaaca tattttcttc gattttttct tctaattgtt catgcagtcc atgatagaga
    15421 tctctagcat cttcatctgg taagaaataa tcataatcaa tctgtaatgc ctttaaatcg
    15481 agatctgcgt gagtacaata aatatcgata tcatgaatgg ttcgtcctaa tgtatcgaaa
    15541 tcttcaagat actgatacgc ataaggacta tttgtttttt cagaattaaa aataggatag
    15601 ggtcttatct tgtttccttt aagatcttca cgctttagcg gtgcaagaac aatggtctct
    15661 ccttttaaaa gactcctaat tcgttcggga ggcaaaatac gatctgaatc aacattacga
    15721 ttgatatgtg tgttcattcc caaagcattg atcgtactat tttcttgttc cactgttttg
    15781 ttgccgacgt tttgagaaaa ttcttcaatc gtatctgtat ttgaagacat aatataaata
    15841 tgtgtttgac aattttcttt gatgatatct gcattatctt caccatattt cgcacgtagt
    15901 tgtttatatg attgaataaa cagatcccat aacatattac gacctgccgt aaccgtcatg
    15961 attccttcca tgttgtccat cggtggcata tttccaaatt catctaaaat gaaatgaatt
    16021 ctacggtgac atttatcacc tttggtctta acacactgtg tagataattc tttatatagc
    16081 tgactaagaa aaatgctaac aatgatatgg ttagatggat cataatcagg tgttaacata
    16141 aaaatagcca ttggtttatc ggtataatgc atccgaatag actctactag taagttactt
    16201 ttactttcat ccagtgtgag aactgcttct ttttcccatt ctggcaaatg agtttctcct
    16261 cgtttttttc gatagacgat gtttcccttt tcatctttca atactttttg agagaactca
    16321 taccaggcca catattcttt tccttggtga tcatatttta agcaaacttg atccccttgc
    16381 tctaaatgac agtcaaaatt aatttcacaa aattctttat aacctacttt gacacgttct
    16441 tcatgaaatt tttttccatc atgatagaac tctacaccaa tacgttgatt taatagactt
    16501 tcgtgtaatt tcaaatctaa atatttggga aaaccaaccg atttataatc aatggttgat
    16561 tgagaagtca ttttcgcaat tttcgttagg gtaaatgggt tcaatcctgt aattgccgtc
    16621 gataaaatat tcccttttgc tttatcagat ccaattttcg ttgctccata ttgttttttt
    16681 gctagatttc caggtggcaa ctgattcata aactcatcta aagcattgag ttgcttaaat
    16741 tcattagtag gatcttgata attgaatcca ccaatttctg aaagtagttc aacgagatta
    16801 tttggtgtta atttggtgta atcccctgtt tgatccgctt gttctaacaa cgcaaaaata
    16861 agcgcattga cagctttttg cgcattttcg ttgaaatatt tattgtcaga agcattcgcg
    16921 tcataataaa tcgtatttgt aaatgtattc gctagttgcg tagcggtatc cacgtctcct
    16981 cgctgccaat atttcacaat taaagccaaa ggattatcac tcatggactg taatggttca
    17041 gttagattat aagcataaac atcatagcct ctggcttcta attcgtcttt gctggctaca
    17101 tacaactcat ttttaggatc attgacgacc aatgaacttt gtttttctgc acgagataaa
    17161 ttatcaatag tcgctaatac ttcaatctgc cctttccctg atcgagaagt gccaataata
    17221 caggtattga cggtatccgt ttggatatac cagtactttt tatagtgagt gataggaatt
    17281 ccaccatatc caggaaaaga acctttcgta tccggtatct gaggatagat ctgttggatt
    17341 tcttttagcg tcattaaccg attatcccct ttttgtccat cggctaacgg acgaaaccac
    17401 atatccattt tcaagcccat aagtacagct ggaacaacac aaatcgtaga aacaactaag
    17461 cgtgtaccta aactcgttgc tggggtcaaa ggattccaaa aaccagctga atcaaaatga
    17521 aagacctgtg gcatttcctg taattgaaac agattcactc cttgtaagct tccttgaatg
    17581 atttcaaatc gactgaaagc ttcaggtatt cttgtcacta aataatctaa agggagatag
    17641 actaaaccgc tatacattag tttttgtttg actcgcttat catgcttacc tggtaatctt
    17701 tcacctgctg gtacatagcg ataaaaatgt gatagatatt tctttttttc taaattaaaa
    17761 ggcttgtctt ttcgtttcgt tgtttctcga atccgcatta tttcacctca tttgattctg
    17821 aactttcgga agagtttgat tgtacagttg aatcgcttga tccttctttg gtcttactag
    17881 aatcactctc tttactgttt tccatacttg actctgttgt tgactgattg gtacgattca
    17941 acaattcttc taattgttgt tcatactctt ttcttgcttg ttcctgggct tcttccttga
    18001 ttgacgccgt tgtggctaca gaatcagcct gtgaagattg attgatatga ttaaaagcaa
    18061 atactgtccc tccacctaga agcaagctta aacttgcaat acatcccacc atccatccgt
    18121 taaaggaacg ctgtggtgaa ggagttagat ttgtttggtt gttcattggc gtttgaacag
    18181 cagctactga aggcattggt tgaagttgtg ctagataatt taattgtgct tgtcgcaatg
    18241 tatccatttg ttcttgacgt tccttacgag cagctgcttc tttttccttt tcttgctcta
    18301 atcgttgttt ttctatcgcc attttttgtt ccgcaagatc ctgttcccgt tttcttattt
    18361 ctaattgttc acgctctttt tctttttgcc gttgtttttc ttcttgttct ttcaattctt
    18421 gttgttgaat ttcatactct tttttccatt ttggaatttg tacttgtaat tcttgctgga
    18481 tctgttcgtg tttttccata agaacttcag ttgttgtttg atatagctta ttcagttgct
    18541 catttaattc tttgctaatc tttagcttat ctgtacgcaa accgcggtag aactcttctt
    18601 ttcgttcttt aatacgttct tttaacaagt tttctttttc tttcgataac gcttcttgat
    18661 tcgtcttagt aaaattgttg atcttttcta cacacaagga ataagcattg tcgcgtttct
    18721 tttcgtaccg ctctttgatt ttttgtactt cttcttcaat cacttgctgt tcttctttat
    18781 ttagttcctc ttttgctttc tcccaattgg aagactgttc cgccgcatac tcattaattt
    18841 cttgatctgt ttcctgttgg cgttcttcaa aggtggctaa tagatcttct tgtgcaagct
    18901 catgccaatt tgttgattgg acagactcta actgttctaa aagtgtgcct ttcccctgtg
    18961 aaattaattc ttctttactc tctaaaaaag cttgataggt ttggggtaat tgatatttcg
    19021 aataaagctc atttaaaaat aattgatttt tttctttcat ccattcatgc tctggcggat
    19081 attgatccaa aatataatca aatacagttg ccttttgtat ctcagtttcg tttttctcta
    19141 cctcttcact gataagtggt tcaatatatt cctgagaatc cccttcagtc catgttggct
    19201 cttcattcgc ttcaactgga tcaatctcta cttcggtcgt ctcttccatt gtttcttcaa
    19261 agggatctcc atccaattga tccattacct cgttctcttc ctcaaatatc gatttctgag
    19321 tcggaatatc agcttgttcg tcaacattgt ctgtctcttt ttcttttgat tcatcctttg
    19381 gaaagattgg gcgttcccat ggaacttctt cgtttacttc gacttcactc acttgattca
    19441 cttttctttg gtcgctctct agctcttctt ctaacacttg tagcaatttt tcatttcgat
    19501 aagactcttc cacactcatg gtttcatccg tttccttaaa cacatcaagg cggatcaaat
    19561 ccatcaatgt aggatagaaa ccttctgaaa tttgataatc cagcggtcca aaaacgtatt
    19621 ctgtaccagc tttctctatt tttccttctg tgtcatgtaa cgtgagagtc aacttaacag
    19681 aagattgact ttcttgttcc agtactttcc ctaacacatg tagttgttct tccgtttcaa
    19741 tgaccgaata tttcattgtt tttggtaaaa aagaagtccg ctttcctact tctttcgttg
    19801 ctttttttat taactcttta tcttttttgg tattgcctgc aatcgtaaag tacatgagta
    19861 ttctcctttc ataaaaaaag gagtaaaaag tacatagcta ctttttactc cttcattttg
    19921 tttttataat ccctgtgggg tttgtccaaa cattccaaat aacgaaacca caatagaggc
    19981 agcagctaaa ataattccta cccccatcaa tacataaccg acgtgcatct tcccgttttc
    20041 agcacctctt cgtccaaata agaagaaaag ccccccaata acaatggaag caacggccgc
    20101 aacaccagca aaaatcatca gattattttt caaactagtt gcggcagttt gtaatgctct
    20161 aaaaatatca accgcagcta ctactttcgg ttgtgttaaa aaattcattg taattgattc
    20221 aaacataaga ttgttcgctc cttttaatgt ttaataattt catcgaaaac aagtttttca
    20281 cgttcacgtt gatagatata tccttctaag tccttatctt ttccccgtaa taggtcaaat
    20341 tgtgcttttt caagaacttc ttgtttccac tgtgtttcag aaacaccgcg acgttctaag
    20401 attttagacg cggctttttc aaatggcgtt ttagcttttg ccattgtgat tcctccttta
    20461 ggataaataa aaaagactag ccatcactcg ctagtctttt gtaatttgta tttatttgat
    20521 tgtgatccat catgaattaa tttctctttc gttcgttttt catccttact agatccaaga
    20581 aaaaccattt tttttacgcc atctttctcg taaggaacaa cgataaataa agaatctggt
    20641 ttattgataa agtcgctaat acctgcagaa tctactattt tgtatctttc taaaccttta
    20701 tagtcttttt gcctcttgac tgttatttgt acaggatctg gatgccatac actttcagaa
    20761 tattcccatg tagtatcgtc tataattttc aaattattaa caagaccacc tacttcttct
    20821 ttccaaacag ttcctggttg caataaacta ttatcttctt tagcttccga tttcttatta
    20881 cttgaacatc cacttaaaat aataaaaaat attgcaaaca tagagacaaa ccatagttgc
    20941 tttttcttca ttttattcct tctttcgttg ttttatttta gtatatcaaa taacgaaagt
    21001 agcaacaaac ctcattttga tacacgggga acggatactc ataatttccc acctttctat
    21061 agaaactttt cctcttgata ttgtgattta ttacaaaaaa gagctataat aaagaaaaaa
    21121 atcaagaggg agcattgcaa tgtacgcaga taagaatgaa atcgaatggt tattatttga
    21181 aagtggaatc tccgttaaag atatatatat ggaatcaggt gtcgcgcgca ctacagttat
    21241 cgacttgatt aataaaacct cctcaatcga taaaatgcgt tttgataatg cagtcaaact
    21301 cactaaaatg gcgaaaatgc gaaaaaactt atatgaaaac aaataataag aaaccaatgc
    21361 ttattcaaaa gtattggttt cttattgtat tttaatcggt ataccgtcat ttactcttga
    21421 ctttgtcggt ataccgacat ataattaact tgtaaaaaca tttaatctat ttaggagttg
    21481 aaaacatgaa attattaaac ccaaaaactg ttatagctgg aacatttgct gtcacactgg
    21541 ctgccacact ttctcttgct ggatctgttg acgctgcttc aactagcgtc atgtatcgcc
    21601 tttataatcc aaataaccat gaacatttct acacctctag cacaaaagaa cgtgatcact
    21661 tagtgaaaat taagtggggt aattatgaag gccccgcttg ggaagcaccg actagcggtg
    21721 gtcatcttgt ctatcgttta tacaataaag gccttcgtga tcaccattac acagctagtt
    21781 gggatgaagt gaaatggttg actaaaaatt acggctggac ttatgaaggg cctgcctggc
    21841 gttctgccga aaaaaataat aaaccgatct accgcctttt ccttcctggt gtaaaatctg
    21901 gctcacatca ctacactgca agttggaaag aagtacaatg gttaaccaaa gactatggct
    21961 ggaaatacga aggtatcggt tggtatggcg ctgacacctc aaaacccaaa gtgaataaat
    22021 cggctttaga agctctttat acgagcgtta agggaacgaa aaaaggtgac tataccgaca
    22081 atacctggaa cgcattccaa accgctttaa acaatgctaa gaaagtgtta aatgactcaa
    22141 aagcgactca aaaacaagtg gatagtgcca aaaatacatt agattctgct tacaaaggat
    22201 taaagaaaaa accagcacct actgtgaata aagctgaatt acaagcttta tacaaccgat
    22261 taaaatcaac tgctaaagga gattttacag aagaatcttg gaataatttt cagactgctt
    22321 tatctaatgc taaaaaaata ctagacgatt ctaaggcttc tcaagcccaa gtaaataatg
    22381 ctaaaaatag tcttgattct gcatttaaag ggttacaaca caaacctaaa ccttcagaat
    22441 atgcggtaac cgtccgtcat atgaatcgac aaactggaac gctgctaaaa gaagaacatg
    22501 tctcagtaaa agctggtaca agttacactg caaaagctaa aaccgacttg actaactttg
    22561 aagcaccaca gtaccaagta aatgggaatg aaacacaaac acaaacgatt aacacaaata
    22621 ccacatttac tttttactat gatgaagtct ttctagttga agtgaaagct cgtccaaata
    22681 aagtgtcgga tactgatccg aatatccaag aactctataa ttatagtaag agttatcctg
    22741 tcgtttatgg acaaagcatc acaattgaag cacctacgtt cactaatttt gttcttgacc
    22801 ctagagaaag ctctagcaac actgtgactt taaacaacgt tacaagcaat caaggaatca
    22861 attttgccta tactcatcaa tacaacgtca ctgtgaacca tataaacgtt gacacaaacg
    22921 ctgttttatc tactgagaca caaacggttt acgagggaga taatttctct acttcttgga
    22981 aaaatatgac cgatcaaaac tacttcttgt gtagaaatga cgattcatct gttaccgttg
    23041 ataaaaatgg acaacgtata attaatcatg ttgaccaaaa tcgaacgatc actttcaaat
    23101 acaaaaatat ctcattaaat gatttaaaca actatgtgcg tcaaaaagaa cttgcttggt
    23161 taaatagcta ccgtcaacaa aatggcgttg ctccaatgca atttaacgac gtcgtacaaa
    23221 aagctgccga tatacgtgca aaagaattac aagtaagctt cagtcattat cgacctggcg
    23281 gcggtacttt ccaagatctc ttagaaagtt taggctgcta cggcgctaaa ggagaaaata
    23341 tcaatagttt ctacctttac gttgacgaga tcctttcaga tacgggagca gtgaatgcca
    23401 tgattatgtg gaaagatagc gctgctcata acgcaaactt actttacaac aatcaaagca
    23461 tcgttggttt atcccacgct tatgaagttt ctgcagacgg atcactttct tcagataatg
    23521 tatttattag tgccaaccca attttcaaat agaaaaacaa ggctgatttt cagccttgtt
    23581 tttttgctta attaaactta agaaccacat aactaaaagt agctaacaca agtaatagta
    23641 agctgaccac taaagttgtt actaaatgtg tagaacctgt tttaggaaca ataacttgtg
    23701 gcaagttagg atcaacccca attgtcacaa catttgtttt attagaaaca ttatctactg
    23761 ctactacggc ttggttatca atattttttt ctgattgtag tggggtttta gctgtaaata
    23821 tcagttggat ttctcgtcca tctaaaagat tgttacttaa gaagttagcg gaagcttccc
    23881 acttcagcgt tcttgaattg ctatcatagg ttagtgtgcc ttcagaagta atatcttttc
    23941 ctttactctt atctattact tgcgcagaac cttctttata tgtcaaacga gcttcaattg
    24001 gatcttgaat actaaattgt ttgtagtgat ctgacgcagc gtctacgcct tttgtgtgcc
    24061 atttttgtgt gactagatat tgtacttcag atcctgcgtt taaaggagct gtcggtgtac
    24121 ccttcttacc gtcatttcgt ccgtttacat cttttccatt ttgttgcact tctttcactg
    24181 gaattttagg gaaataaacg gtaatgatat ttgtatcctt ttctacttta ttaatgatcg
    24241 acgttccctg atttttggct acactatttt gattggccaa ttcattgact tttacattga
    24301 tcactaattc gtaagtttcg ccgttatact tcattcgatt ttttaatgta tcagctttcg
    24361 ctgcatattt tacctggtgt tttgttttgt cataggtcac ttcaccagat acatcgaatt
    24421 ttttatttga tccacattct acgtgtgcat cgacgtaatt tacttctttt ggtaaattat
    24481 caattaactc aaatcgatcg taaaccgcta gtaaatccac tcctaaacga ttcacttttt
    24541 gtttgattcg atattgaatc gtgtctccta cttgcaacat tttatcgttc acgttatttc
    24601 catttttatc aacccctgtt ttttcaggtt gatcaggaac aacactaaag attgtcgcag
    24661 aagataaagt aaaccaggtt tgaacattag aagaaccaat cacaaacgtc ggatttgctt
    24721 cagatatttt aaaggacacc gtaccttgac caaacttcgg atctcctaat ttatcatgca
    24781 aattattgaa atcattatcc gcttgtgtca gcttagagct tcctcctggg tggccaccta
    24841 ccacgttcag attgttgtag aaagatttaa attctgaaag aaccgtatct tttctgacat
    24901 accaatctgt cgtattcatt ttgtcatagt gggcatattc tcctttaaga tccgtgcttt
    24961 ttcctcctgc agggttcaaa gagttaaaac tgataaatgt atctcctgaa aattgaacgg
    25021 ggctaccgtc ctcatatgtg gctactagct gcacattcat ttgtgttgca tggtaaacaa
    25081 ttcctgagaa aagattgtct gagatccaaa gtactgttct ttttttagat ttactcattg
    25141 caccattcgt atttttatag ccatcgtctc gaaaatgagt ctttgtatag ttgttatcta
    25201 gaatattcca tggcaacgta tctgaatata agtggatatt agatagaact agcttgatat
    25261 tgactttttt cccgttatac gtaccgattt ttccgtagtc aatattgact ttggtgttgg
    25321 ttgttacgcc ttctaaaaca aggtttgttt caccgtattc tttttggaaa gaaggatagc
    25381 gtatattttt gtttccctcc actaatccta cgtagtcgtc tgtaaaacca cctttgttgg
    25441 catcaacatg atatttgtaa actttggacg ctccgcttac agtaatattt gtttttgcat
    25501 taggtacatc ttttggaata ataaaattat tctttacgtt ctggattgga tttgacggat
    25561 cgacaataac tttttcagca aagacattgg ctgtttttaa cccaaacaat gtacctaaca
    25621 tcatcattat gggaaaaaca tattttaacc gtcttgtcca cgagtgttta aaattcatcc
    25681 cttcatcccc tcttttttat aaatgactag tgaaattccg acaacaacga tcaaattgat
    25741 cgtagtaaat agtggattcc taatgagctt ttccataata tctagcggca tggaagcagc
    25801 tggtatgttt aaaatcctca ttaggtatgg ttggtaactt ggtaaaatag ataattgaga
    25861 aaataataaa ccgcagtaca aaaagactgc ggttaaacaa gaaagattga ataataataa
    25921 tttgatcagt ttcatcttat ttcttcctta atctctagaa aacaagtgag tcacaaaatc
    25981 ccaacaattt tcaaagaaat ttttctttac gccagtagaa acgatttttt tcacttcttc
    26041 tttaggttgc gaagcttctg atttaggata gatccacaca tcctttaaga attcaccgtt
    26101 tttatcagaa acaggtgtta atagcaaaat atcctcgcta ttagaaatgt tttcaggact
    26161 tgtttcattg acaatataat aagcttgttt ctgatttgcc tgtacttcta ccgagaattc
    26221 aaagacacct gtttgttgac caattgtctt tgtttctcca ttagaaacta gcttcaattg
    26281 atcactggat aattttttca ctcgatcttt caattgggat tcaatttggt cagtagtgag
    26341 attcttaaca tccatctttt gtaaaatatc cgatacatca taaacagaaa acttcgcgcc
    26401 atttactcct tcttgttttt caagcttttg cccctggttg tctaattgtt cggaagaaat
    26461 aatcttttga acgtgaatgg tctgtttgac tatttgatcg tcttcagcaa ttttaggttc
    26521 ttctgaagaa tcaactgttg acgaatcgac ggtttcatcg ctgctttgaa tcgtgctgct
    26581 atctgacgtt tggattgttt gttctgtgct atccgtgctt tcttgactgt ctgcaaacgt
    26641 caactgtgtg taggcagtga aagaaagaag agcggctgca caaacaaata gccattttct
    26701 atttctcatg ttggttaccc tcctttattt tttcttttta taaacaaata gcgaaccaat
    26761 gatcatgact gaaagaaaaa cagtgcttcc taaaagccat ttccaagata atttttgttt
    26821 cttatttttt tcatctttta attctgattt tgtaaaggtt actcgtttcc catacactag
    26881 gaaacggtgt gtgttgattc ccttaggcgt acatgtcatt agcgttactc gatcttcatt
    26941 gggatttggt tctaagtaag tgacaaagtt tctttgtagt tcgtcttttt gcacttcctc
    27001 aatccgatcg atttgataag cgtgctgctc accatcaact ttgatataaa acttttctcc
    27061 tttttttact gaaggtaaat catcaaaaag attatcttta taaagtccac tatgacctgc
    27121 gattaaagga tttttaccgt ttcctcctgt aatatcacca gttccttccg taatacctac
    27181 accattttct aaaattttgt cggacgttcc gtcataaatt ggtagtttta aagaaatact
    27241 tggaattgta agaataccaa cggaatcgcc taactcaatc ttagcaacat ccaaagaaga
    27301 atccgtttct gctgccgttc ctgttcgatc gattgcgaca atctgctgat tttgttggta
    27361 tttcgccacg ctcgcttcag caggcatcaa aagtaagaca cctgcagctg aaagtaacca
    27421 gaaagcaatg atccatttac ccatgattcg ctttttctta ggcttcctga taatcattgg
    27481 ctttgatcct tctaggcttt cttcttaaag taaacaactg cagaaagtgc ccctgctcct
    27541 agcaacaagc aagagatcaa tacatacgtt tggaaaccgt tactaccagt cattggtacg
    27601 gaagcttttt gattgttttt gatcgtgatt cggttttctt ctttgtatga atctttgtct
    27661 actttgaaag agatctcttt cgttaatttt tgatagtttt caggcgcttt tgtttcttcc
    27721 agtgaatatt caccttcagt taaaccggtg atttcaaagt gaccttcttt atctgatttt
    27781 aggatcgctg catttgctac atcgtctacc catactgctt ctttgacacc gtctttatcc
    27841 gtatcaacta atccaccaaa atattttcct tctgcgtttt tagcagcaaa ttctgcgcct
    27901 tcaagcggtg ttgctttgat tcctgttcca aatagtccgc tatcgacttt taagaatttt
    27961 gcaccataag tcacaacgtc agctttcgtt ttttcgtggt gttcttcctg attaaatgga
    28021 ttgttgttat aaacgaaatc cacgctattt gttaatggat tggcaacagc tgcgctgtca
    28081 tttacataca tgttataagt catttgaaga tcttgtccgt gtaaacttgc tacagtatca
    28141 cttacttggc cattattcac gataaaatcg atcacaaagc cattttctga attttggatt
    28201 ttataatctg tattttcttt taataccaca gatccatctt tatttgttac tttgatattt
    28261 gctttagcag cgacaaaaga aagtccttgt cctgctgtat ccccccattt aaatacactg
    28321 taaggagaag tttcgcttgt cacaccgttt actgtgatac cgtctgcgcc acctgcgata
    28381 tctgtaggga tatgaattgt accttgataa ttcactgcgt caccaatttg gaaagaatgt
    28441 tcttgtcctg ttccatttgt cactgtttta tcgatcactg gtgctttata gttcacatat
    28501 gaagctttta aatcgcttgt cacaccgtca ttcgtaattt caaaggttaa tttattgtgc
    28561 gcatcgttgc gagcgtctgc gcctaataaa tattgatctg ctgttggttc tttatctgat
    28621 cccactacaa cttctgaagg aacttccaca aaatagtatt ttcctaacgt caaatcagtc
    28681 gcagtcagct ttccttgatc atccgataca agatctccta attttgttcc ttttccaggt
    28741 tcgcccttgt ataactcaaa ttttgcccct tttaaaggtg tttgtttgct ttgagctgtg
    28801 ccatcgtcac caaatttcgt taattcaaaa ctcaacttag aaacaatatt tttaggatat
    28861 aagtgaatgt cttttaaaaa acctgaacct gtattatctg tcattggcgc aatcacaacc
    28921 attggttttg ctttttgtgt gactaatcca gcagcagatt tactttcata caccacatat
    28981 acattccctt tggaattgac ataggctggt tgatccgcaa aagtgatctc accattttca
    29041 tctacagctg aagtaatttt attggttgca ttcttgacgt actcactgtt agatcccttg
    29101 tcttctacat ctttaacgat ttcgtccact ttcgcgttgg ttagatcaga atcttcagtc
    29161 ggtaatactt gatccgtaat atttcctaac gtaaactcaa catcaccata atctgccttg
    29221 ttgtatttcg ttacacctgt aggatattga tcgtgcgtat aaccatcgtt tttgatcccg
    29281 tcaatatcaa cattcaattg cgttccttga tcgtacatta atttatgaac cgtgatattg
    29341 accttctctg gtggcgtttt ttgcgtgaca tcttctgcat gtgcttgata cccctgaaag
    29401 cagcttgcaa tgattcctaa cattccaaca agcattccag ctttttttac ataccgattt
    29461 attgccattt tttactctcc tcatttcata tttcaacgac tcgcgttgat taaaaccttg
    29521 ttattgtagc tctccctgta ccacgtatct ttcttttcct tgtgacgtat aaacacaagt
    29581 aaacaacgtt aataagggtt tctctccttt ctttggcaaa gacaagaaag agttctcttc
    29641 aggaacgcca tcgattaatt taaagtactc aggtacgata aatttacgcg ttaccttgta
    29701 acgatagacg ccatcgttac taactaagtc catcacctcc cctaatgaca acttttgaat
    29761 atcagaaaat aaaacacctg gcatttccat gttatgacct gctaggacat agtttccttt
    29821 gcccatttcg gcatcttcat aaaaataagt agccgctcca agactcaaag tgtattgatt
    29881 tgccccttta aaaattggca atgctaaacc aagtgcagga atctgaattt gtgcaaatac
    29941 ttgtttattg acgcccattt cgattgcttc tttttgtatg gacaacattt gccccaaaga
    30001 catatcatta ttgacgttcg ttgcatcctc cttataactc tttgcgtgtg cattgatttg
    30061 atctacgggc atcttttttt ctatattttg cttaaacacc tctccttcat gtttttggta
    30121 gctaacatag ccaaacacac tgcaaaagac gattaaagcg actcctaaaa aaacaaataa
    30181 ccattttttc atccatctgc ctcctttcag acaaaacaaa aaaacttttt ctcatttcca
    30241 tagaaaaagt tttaaaaatg aattctataa gttcgtctca actgttcaaa gtttttcatt
    30301 gaacctaaca aacaagcttt ctcttttcct gttaactgca tatcattgat atattgcgcg
    30361 acagataatc ttttaaggtg tttttgcttc atcgttttta gtaacttttc ttccatttct
    30421 ttcgacactt tttttctgtt ttcgatttct tcataattca tgagttttcc taccttcctt
    30481 gttttttgca aaaataaaaa agcctatgat cacatacgct ctacacttca gtcttgggtt
    30541 atctttttct ttcgtttaat tactggccgt gctggtttca aatccttgat tccattatgg
    30601 gttctccaat aatcgaattc ttttcgcaat ctttcttttt ccatatctgt tcctttagat
    30661 aaggctttga atacttcttt aggtgaataa ccacgagcta acagctgtac ataccttcct
    30721 tttgtcaaag tatccatatc catcgcctct aaaactggtc gcgccatcta
//
LOCUS       DAFEML010000028        30326 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFEML010000028
VERSION     DAFEML010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.028"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..220)
                     /locus_tag="LP468_001448"
     CDS             complement(<1..220)
                     /locus_tag="LP468_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL2080991.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
     gene            complement(217..510)
                     /locus_tag="LP468_001449"
     CDS             complement(217..510)
                     /locus_tag="LP468_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080992.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(547..684)
                     /locus_tag="LP468_001450"
     CDS             complement(547..684)
                     /locus_tag="LP468_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL2080993.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(686..1117)
                     /locus_tag="LP468_001451"
     CDS             complement(686..1117)
                     /locus_tag="LP468_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080994.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(1131..1625)
                     /locus_tag="LP468_001452"
     CDS             complement(1131..1625)
                     /locus_tag="LP468_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080995.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     ESVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(1625..2074)
                     /locus_tag="LP468_001453"
     CDS             complement(1625..2074)
                     /locus_tag="LP468_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080996.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(2078..2695)
                     /locus_tag="LP468_001454"
     CDS             complement(2078..2695)
                     /locus_tag="LP468_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2080997.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(2695..3603)
                     /locus_tag="LP468_001455"
     CDS             complement(2695..3603)
                     /locus_tag="LP468_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL2080998.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            complement(3616..6375)
                     /locus_tag="LP468_001456"
     CDS             complement(3616..6375)
                     /locus_tag="LP468_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2080999.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            complement(6372..7076)
                     /locus_tag="LP468_001457"
     CDS             complement(6372..7076)
                     /locus_tag="LP468_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2081000.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(7088..9397)
                     /locus_tag="LP468_001458"
     CDS             complement(7088..9397)
                     /locus_tag="LP468_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL2081001.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGGVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(9592..10056)
                     /locus_tag="LP468_001459"
     CDS             complement(9592..10056)
                     /locus_tag="LP468_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081002.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(10056..10682)
                     /locus_tag="LP468_001460"
     CDS             complement(10056..10682)
                     /locus_tag="LP468_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2081003.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWTSSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(10689..11054)
                     /locus_tag="LP468_001461"
     CDS             complement(10689..11054)
                     /locus_tag="LP468_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL2081004.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(11044..11382)
                     /locus_tag="LP468_001462"
     CDS             complement(11044..11382)
                     /locus_tag="LP468_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081005.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(11372..11698)
                     /locus_tag="LP468_001463"
     CDS             complement(11372..11698)
                     /locus_tag="LP468_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2081006.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(11679..11957)
                     /locus_tag="LP468_001464"
     CDS             complement(11679..11957)
                     /locus_tag="LP468_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL2081007.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(11959..13323)
                     /locus_tag="LP468_001465"
     CDS             complement(11959..13323)
                     /locus_tag="LP468_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2081008.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(13336..13905)
                     /locus_tag="LP468_001466"
     CDS             complement(13336..13905)
                     /locus_tag="LP468_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBL2081009.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(13877..15064)
                     /locus_tag="LP468_001467"
     CDS             complement(13877..15064)
                     /locus_tag="LP468_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2081010.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(15128..16855)
                     /locus_tag="LP468_001468"
     CDS             complement(15128..16855)
                     /locus_tag="LP468_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2081011.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(16852..17304)
                     /locus_tag="LP468_001469"
     CDS             complement(16852..17304)
                     /locus_tag="LP468_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL2081012.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(17416..17796)
                     /locus_tag="LP468_001470"
     CDS             complement(17416..17796)
                     /locus_tag="LP468_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2081013.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(17793..18179)
                     /locus_tag="LP468_001471"
     CDS             complement(17793..18179)
                     /locus_tag="LP468_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081014.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(18181..18459)
                     /locus_tag="LP468_001472"
     CDS             complement(18181..18459)
                     /locus_tag="LP468_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081015.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            18507..19235
                     /locus_tag="LP468_001473"
     CDS             18507..19235
                     /locus_tag="LP468_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBL2081016.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(19381..19857)
                     /locus_tag="LP468_001474"
     CDS             complement(19381..19857)
                     /locus_tag="LP468_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBL2081017.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(19817..20164)
                     /locus_tag="LP468_001475"
     CDS             complement(19817..20164)
                     /locus_tag="LP468_001475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081018.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(20151..20336)
                     /locus_tag="LP468_001476"
     CDS             complement(20151..20336)
                     /locus_tag="LP468_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081019.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(20337..20609)
                     /locus_tag="LP468_001477"
     CDS             complement(20337..20609)
                     /locus_tag="LP468_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBL2081020.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(20606..20809)
                     /locus_tag="LP468_001478"
     CDS             complement(20606..20809)
                     /locus_tag="LP468_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081021.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            20934..21146
                     /locus_tag="LP468_001479"
     CDS             20934..21146
                     /locus_tag="LP468_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081022.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(21179..21373)
                     /locus_tag="LP468_001480"
     CDS             complement(21179..21373)
                     /locus_tag="LP468_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081023.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(21381..21569)
                     /locus_tag="LP468_001481"
     CDS             complement(21381..21569)
                     /locus_tag="LP468_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081024.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            complement(21566..21706)
                     /locus_tag="LP468_001482"
     CDS             complement(21566..21706)
                     /locus_tag="LP468_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081025.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(22196..22561)
                     /locus_tag="LP468_001483"
     CDS             complement(22196..22561)
                     /locus_tag="LP468_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081026.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(22601..22903)
                     /locus_tag="LP468_001484"
     CDS             complement(22601..22903)
                     /locus_tag="LP468_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL2081027.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(22903..23202)
                     /locus_tag="LP468_001485"
     CDS             complement(22903..23202)
                     /locus_tag="LP468_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081028.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(23195..23359)
                     /locus_tag="LP468_001486"
     CDS             complement(23195..23359)
                     /locus_tag="LP468_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081029.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(23365..23634)
                     /locus_tag="LP468_001487"
     CDS             complement(23365..23634)
                     /locus_tag="LP468_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081030.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(23646..24395)
                     /locus_tag="LP468_001488"
     CDS             complement(23646..24395)
                     /locus_tag="LP468_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081031.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(24398..25084)
                     /locus_tag="LP468_001489"
     CDS             complement(24398..25084)
                     /locus_tag="LP468_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081032.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            complement(25090..25761)
                     /locus_tag="LP468_001490"
     CDS             complement(25090..25761)
                     /locus_tag="LP468_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL2081033.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILEKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(25754..26095)
                     /locus_tag="LP468_001491"
     CDS             complement(25754..26095)
                     /locus_tag="LP468_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081034.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(26273..26971)
                     /locus_tag="LP468_001492"
     CDS             complement(26273..26971)
                     /locus_tag="LP468_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL2081035.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            27058..27528
                     /locus_tag="LP468_001493"
     CDS             27058..27528
                     /locus_tag="LP468_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081036.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(27571..27750)
                     /locus_tag="LP468_001494"
     CDS             complement(27571..27750)
                     /locus_tag="LP468_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081037.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(27737..28075)
                     /locus_tag="LP468_001495"
     CDS             complement(27737..28075)
                     /locus_tag="LP468_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL2081038.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(28091..28294)
                     /locus_tag="LP468_001496"
     CDS             complement(28091..28294)
                     /locus_tag="LP468_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081039.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(28309..29085)
                     /locus_tag="LP468_001497"
     CDS             complement(28309..29085)
                     /locus_tag="LP468_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL2081040.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            29384..29704
                     /locus_tag="LP468_001498"
     CDS             29384..29704
                     /locus_tag="LP468_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081041.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            29722..30153
                     /locus_tag="LP468_001499"
     CDS             29722..30153
                     /locus_tag="LP468_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2081042.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
BASE COUNT         8511 a         6333 c         4659 g        10823 t
ORIGIN      
        1 tgtttcctcc ttcttcgctt tcagccgaga acattttgta ggttcgattt gatacaccca
       61 acacactccc taaaaacgcg ccaaaaccag taatgatgac aacacagata tctgtgtact
      121 gccaattgag cgctttacca actaacccca cgaaagtagc tagtgcggga ataattacca
      181 gtgcgaacca ttttagtact tcgaacgttt tattattcat tttcttctct ccctaaacaa
      241 agttttgatt tgttgcgtgt gttccaccaa tttttctgta tgtgtatcta atctttcatc
      301 gtgtttcttt agttcttcat gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt
      361 agtcagcaaa tctaaattgt ggcttacttt tgaaagagtc tcagtaattt tcgagaaaga
      421 tgcagcaatc ggtctaatta ctaataaaat caaagaaacg atagcggtta ttgatcctgc
      481 tatcattccc cattccccta aattaatcat gtgacaactc ctttacctta aataaaaacg
      541 catcaattaa gatgcgctct tatctttatt aatgatttta tctgcttctt cgtctgtaat
      601 gcataatgga acgaaaacca ttacttgttc gttagtgaaa cagccccagt catacattag
      661 tttgatatct tcatatgaat acatgttact tcccaccttg taattgtttt ttgatttctt
      721 cgatttcctt ggtattttgt acagaagcaa gcatcgtttt tgaattcaac tgcgctaaac
      781 tttctgactt ttctttcaat aagacatttt cttgcttgat tgctacattg tttagcattg
      841 ctttagaatt tagctgtttc aattcatcat tttctgcctt cagcgtttcg tataatgcct
      901 taatattagc caattcatct acgctatcaa cagcattccc ttttttctct tcttcagtag
      961 ctaactcaac ccactgtttt ttatcaaaat caaatcttgg tctccagtta ggaactggtg
     1021 gtttaatctc tgtacagttt tcagggatat tttcttgatt gttcaaaatg atttgctcga
     1081 atccgtaagg cttgattgat ttgtaaacta ctttcattag atttcctccc ttaaattgaa
     1141 taagtgataa caaatgaata agctgatcca taacttgaat ttcttctcca tttaatggct
     1201 ccgtctgcgc caatagatag ttgagcactg ttcaaagtag aacggtctat tgacccaacc
     1261 agttgttcaa aactaattgg tgtccgatag ccttctggaa cagttaaaat aaccgactca
     1321 ttcccgccac tactttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca
     1381 cgataaagct ttgctgtccc tgtattaccg ttagtgacaa ccagatttac cacttcatat
     1441 ctgttatcat cagtcgtcaa aacacgttta ttattgattg ttacagaacc tgaaaaattc
     1501 ttatgtcctg caatggcttg gtctccatct gtctgcacca atgcttcttt accatcaata
     1561 gcttctacat gcgtttttaa gtatttagca actccgtctt cttttaattg aacaatatca
     1621 gccattaaac cgtccccact ttctcaaatg taatattcgc taatccatca agtttcactt
     1681 tatcggttgc tgacattaaa cctgctgtcg tagttgtagc attacctgga tttttctgtg
     1741 ctccagctgc aattccatcc aacttagttt tatctgtgga cgacatcaac ccatttgctg
     1801 tagttgtagc tacagctgta gttgtggcat ttattccagg atcaccttta tctccctttg
     1861 gtaaaacaaa attaaatcta gctgcagatg atgttcctac attcgtaaca gaagcggttg
     1921 aaccactaga aacggttcct atggtaattg ttgctgcttg gccaggatcg cctttatctc
     1981 ccttcaccgt tgttggtttg ccttctatag cattccaatg agtttgtgga taaacctgta
     2041 cattgctttg ttttattttt acgatatctg tcattctcta tacctcccca attttttcaa
     2101 aagtaaaatt tggaattctt tcgtttgtgt aattttctgc ttgatttaca gcttcttgga
     2161 atttttgatc tacatatgac tgattaacac caccagtccc actaccacct gtagaactaa
     2221 ttgttccatc ttctgcaatt gatatatttg cacctgcttt taatattttt agagattcta
     2281 attttccttt taattcttca gagaaattga agtctgtttg cttagttgca gataaaacac
     2341 cttcttcagt aacttctaag agttccccaa cttttatacc tcctaattgt tcaggagtag
     2401 caatcggcaa aatatatgtt ccaccttctc catttacgat cttttgaaac atttcagcag
     2461 taagaatacc atcgcttgtc tcgcttgcat aaggtagttc agtaattgca ttctctaatc
     2521 ctaaatcagc tttcgttaaa atgactgcac catatttacc attaaccgaa agaacttttg
     2581 attgtcctga tatcattttt tctaagccta aaactgcaga gacatgtgta attggcataa
     2641 attgacgttt aacaccagat tcatcagttt ccatcattct ctttacttta accatcaaat
     2701 caccccaact ttctcaagag tgaaaacatt ctgttttgga tcatcaacag ttgcaataat
     2761 caaagctcct tcttcaattg gaaattctac tgtttcaatt ttttcgactt cgtgattatc
     2821 tgaaaagaga tcgtcttgaa gaatatcagt cacttcaatt tcaccgtatt caatcgtgaa
     2881 aagtgctgct ttcatttttt gatacaaata atttagatcg gataggaaac gttcagaaat
     2941 cgattcatgg cgtacacctt gaagatctac acgtgcatcc attaattcgg ctaacattac
     3001 tccacctgga tcgatagact tcaaaatatc cttgattgat tcaaaccatg acaagtaatc
     3061 tgattcttgt ccttctctcc aatcttggaa actattctcc tgttcctctc tccagcgatc
     3121 aaattcttct ttcctttcat tcatccagtc cgtaaaatcg cctttatttt cattaataaa
     3181 atctgtcata tcagcaatta aatcttcaat tgattgccaa taagaaccca tttctccttc
     3241 tgtttttgaa acagcattga tgacaaaata agagaagtct tgagttgttc caatcaagtc
     3301 ttctccttta aatataatga aattggctgt ttgtcgatgc aaacactgca tggaatattt
     3361 atcaaaaata tatttgattt tccctttttt agcatccaca atttttgttt ctaattggac
     3421 tggatatttt ccgccaacaa ctgattcaaa atatacctta cattctgata aatcatatgg
     3481 aagaccattt tcgacaattg tagcttccat aacttcagtg tttttattgc cttgtcgaac
     3541 ttgaatcatc cccacgtaat tatagggttc tgttgtactt aatatgacat tccactttgc
     3601 cattaaatca cctccctatt ttggtggtat gacaatggaa gaaattgcac ttgcactata
     3661 atactgtcga tctaactttc cacaaatcat acctaactct gtgttttgtt cataagtttg
     3721 catacgacca ttagctaagc ctcggataac gccagtatgt ccataagttc catctgcaaa
     3781 ccatgaaccc acttgtccac ctcttgccca attaataatt gcaccaacta ctaattgatc
     3841 atatctaggg ttttgaatca ctttccaacc aacagcagac caatcatagg caataccaat
     3901 atcagatgct gcagaagtat ttcctatcac atgagttaaa ccatattttg ttccagcacc
     3961 catgccacaa ccacccagat atcctgaata ttctgcagac aagccataac actgaccatt
     4021 gccaattcgt tgtccaatca aagactctaa atgttttagt cctgcttctc cagtagctcc
     4081 tcctggtttt aaatctttaa atttgttata ccagttaact gcataatctt gacgttcagg
     4141 atgtgtcgct gccggacgtt catagtttcg ttcaaaagca tatgctgctt gtcttggatc
     4201 agtacaggcc ttaaatccat caaccgtcgt aggttgtact acgcccatcc attgtccatt
     4261 tgtaaatgtc caaataagca atcgaacttg tgcatctaag ctcgttattg gttctttaat
     4321 acctgcagca ttaaataagt tttgaacata aacttttcca tcccatgttg ctggaccaac
     4381 aagaggatat gaagaaccat cccactgaac taatccgtat gctggtccac ctatttgaac
     4441 agtatcagga tcaaaagttc ctcctgtttc ttgttgaatg ttccccaata ttccacatgc
     4501 agattgtttc gtaaatccgt tattacacaa aatatcgtat attctccaag ctctcttttc
     4561 tgcatctgtt tttaattcat caggataccc accaggtgtt tctcctccgc cagatggacc
     4621 gccattttgt cctggtatca cttctttacc tctaacagta agttttccct gaatatctaa
     4681 atcaccgaaa taatatgctt ttccgtttcc taataacaca aatccttttt ctgcagttgg
     4741 agaaattaaa atgtattttc catcgccatt tgtacgtatt accaaagaat tttcctcaag
     4801 aggtgtaggt gttacagcat ttggaaatgg atttcctgct gaatctgttg ttccgatcgt
     4861 tccaatggat tcttttctat tccagaattc catacctttt ttggttagct ccatgatttt
     4921 tttgttttca ttccaaattt gaagcgtgcc ttttacaagt tttaacacat caccataagc
     4981 attaaaggaa gtttcgaata cttctgcatt tattgttcct actttgatga agtcagcaac
     5041 aatttctcct tttgatgtga tagcaatacc gaacgggcca tttactccgt tgtctgaata
     5101 acctaagcca tttaaattcc aacgccacac tcgctttgca ttcgccacat ttggagtatc
     5161 catgataaga atctctgatg gagctttttc tggacgaaaa acgacatgcc caccagaatt
     5221 accagtgatc catgccgtcg cattcaacac attttgaact aacgtttctg ttcgattgtc
     5281 gattttcttt ttcaattctt gtgcttgagt atttactgcc gaagtgtaca gtgataaatc
     5341 attacctaaa acaatatcct tatatttccc aagcgttggg aaataagtgt attcgaccat
     5401 acgctctttt atctcgatat ctagctcttt cgccctaaca tgagcgacat caccaaagtg
     5461 taaagacgct agctcttgat acatgtcacc gtattcgagt gtgtgttcca acgccaccat
     5521 actgactgta tgagtagctt ttggctcatg gatacgatca ttgtcaaata aggttttgcc
     5581 ccatttgatc aattcatcaa ctgttttaca atctccgttt tcacgtttgg caatacgtcg
     5641 attctcgttg gttactccat caatttctaa ataaccatat tcgataggtt ctttgtcttc
     5701 atcataatcg ttatcaggaa caccgccaac caaatacaaa ctattgacaa ttgattcttc
     5761 atcaatttct tcttcgattg cttctaaatt gatgccaaaa tcaatccgaa aaccattatc
     5821 tgatccaatc tgttttacca gtttcaaatc atagttatcc atatcaagtt ccgcgctagt
     5881 cacgccagtc aaattttgat taccgttatt tgaaccaatg attgcttcaa ctggcgcgac
     5941 ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa agatagttaa atttttgatc
     6001 aaatgccaaa ctgtttttaa gattggtcat gatctgagac ccattgccgt tatccgtaaa
     6061 cgacttgaca ataaagttct tattggccat aaaaccaata tgccgagctg ttacagaaac
     6121 ggaggtcaaa ttctttttga cattataaat ttcaaaatat tgccatgatc catctggtac
     6181 cttcgctttt ataaaatttc ctttttttaa ataagagcga tactgtccgc ttcttgaata
     6241 gttaccataa aaacgatatt ggccattcag cacacgattg atttctggca aatcttccca
     6301 atcaactaac gacgctccgt tcacgctcaa atcatctggc atttttttat aagcataaat
     6361 aaattcttgc gtcacagata cacactccta ttccaaaacc gcacttcttt aaattttccg
     6421 gatattttta cctgattcca ttcaggctgc aatactggcc aatcaccacg cgtaaataaa
     6481 ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa ccacgattgt tgcagctaac
     6541 gtattaagta ttgttaggct tttatcaccg acagcgatcg ttatatctcc tccgttcgat
     6601 tctatttcca gatagggatg tgcaatttcg tcaccatgat caaaaatatc cataacacta
     6661 gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga gtggctgaca acgaaaagta
     6721 acatcgaatg tataaaagaa gccccactcg ttttcgaaag ggacttcttt atccatgctg
     6781 cagatagcct ctagatactt gtctggatca ttatgtgtga ttaattggct tttaccagtg
     6841 agccatcgtt tgacttctct cagtttcgaa tgtggaatag tgatcccttc tatttccaaa
     6901 tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc cgcttcggcc ctgaatcgtg
     6961 taagtttcgt atcgcttgtt cggcataata tctggaagct ctgcctcaat gatgcaattc
     7021 atatcaatta ctgcattccg atttttccaa ataaaatttg gttcatctgg attcataaat
     7081 tgtcgactca aataggaaca cctcccaaat cacgaatagc ctgtttgttt gctttagcaa
     7141 atttacgatt catacgatct aactcagatg gattgtttgc atcgactttg ccaatgtgta
     7201 tatgctgttc aatgctacct ccagaaactc ttccactgat ccctttgcgt ttttcttcgt
     7261 ctgataatgg agtaactgtg gttttaccat tcttggcagt cagtaactca ggtccagctt
     7321 caccaacaat cgcttgtcca ttgattagat gaccgccttg tgctaaataa ggcagttttg
     7381 aaatagaaaa tgattttcca cctacaccag gaacccattt tggtatcttt atattattca
     7441 atccaccaat aaatccattg atcaatccaa tcatggcatt aataggagct ttccctacag
     7501 caacaatacc atcgaaaata cctccaaaaa tatcaactag accttgccat gcttttgacc
     7561 aattccctgt aaatactcca gtgataaaat ctagaaaacc actgaaaatt cgttttccag
     7621 cattataaaa attattgaaa tttgctataa caccatcgaa aaatccacca aaataaccac
     7681 ttaaaaaatt aaatatttca acagctacat ctgaaacacc tttgaagaaa gaattcactc
     7741 catcatgaaa ccatttaacg ttattatatg cccaaattag tccagtaact aatgcgccaa
     7801 tagctataac tgctaatgca aaccagccac cagacattcc aaataaacca gcaagtcctt
     7861 gccaaactcc tataaaactt ttaactcccc caacgatttt tgttacagat cccatcagcg
     7921 aaccaagaac gattagtact ggtccaactg ctgccgctat accagcaatt gttatgatcc
     7981 aattctttgt atcttgatct agagaccccc accatttaga gaattcctgt aataaggaag
     8041 ttgctttttc aaaaaaaggc aaaaggctta cttggactgc ttcacctacg tcagccattg
     8101 ctaattttgc attgttcata gcttgatcgg cttgatcaat tgggtcgaga gtagcatcga
     8161 atgtgtctcc tacagctccc ccactttctc cagcagtttt tgctaaatct tccaggttca
     8221 aagtacctct acgaattgca tcggccattc taggaccgcc tttagtcccg aatacttctg
     8281 ctgctgcatt gatggcttct gtttcagaac ctgcattttt taccttgtct tgtagttctt
     8341 ctagtccttg acttaaagat tttccgtctt tcgcataagc cactgttgct ttagataaac
     8401 tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa ttgtccaagt aaagtgaccc
     8461 cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc gccatcaatt gctttttgca
     8521 tcaagtcgtc tacagattga ccagtattct gcgatgtttt cgttgttaca tcaaggacag
     8581 aattcaaatc atcatattct agtccataag catcaatagc ttgtcgagca gatattgctg
     8641 attgcgaaac atctgtatca ttgatttcag cgtactgtag gagataattg gttgaatctt
     8701 ccagtttttt atccatgaat ccaaattgtg tatttacctc accaatagct tccccaaccg
     8761 tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa agactgtgaa agtctatcag
     8821 cttgatcacc tgttgctccg gtttttgtaa tgatggtatc aagtgcctcg tcaacttcac
     8881 caaatgctgc aagtcctgct gctcctgccg ctacaatagg cgcggttact ccaacagaca
     8941 ttttttcacc aacgcctttt actttctcac ctgtttcttc gattttctgg agtttttttg
     9001 ctgtatcaac agaaacgtca ccttgttctt taagtgcatc gttcgtctgt tctaatgctg
     9061 tacgaagttt attttctccg gtttcagaat tgagtaattg tttataaagt ttttctgatt
     9121 cagcagaata ttcaccggtt tctttgacag atttttcata ttcctctctc agcatttgag
     9181 atcgttgttc agccaatcct aattgttttt ctaatttttg tttagccgct cgcaattttt
     9241 ctgtttgagt tgcatccttg tccatcgcag acacttggtt tttgtactcg gcagcggcta
     9301 agttcatttc tttgttgatt tctttgattg ttttcgaata actgacttcg ccattcgttt
     9361 taaaattaag aacgacatca gattctttac cagccattta tcttagcgct cctttctacc
     9421 accaaggcga tttatccata gttacagatt gaggtggttc aaaatcggtg ttttgttgta
     9481 accactgtaa ataagatttg agccacaagt taggtgtaga ctttaaaaag aaactctcac
     9541 tccaattcaa tagagtgaga gcaacgtaaa tataaaaact ccaaggagtt cctatctctt
     9601 ccgattcttt ttgtttttct ttctttttgc ttgcgctttt tgaaagtctt gtggcttctt
     9661 ggattttttt aggtcttcca cctgaaatgt ctggctagca aaaatttcca tacaggtact
     9721 ataagcagac aacacctctc cactcattcc caaaaatttg aaaatagttt ctggatcttc
     9781 ctctaaacca ccagtacgca gcatggcata aatcaaggca cgcatgattt ttagatcact
     9841 aggcgataag ttagcagaag aaatttgtcc ttctttttta gatagcatgg cgttcatatc
     9901 agattcaaat tgcgaataat ctccaccata cacatctgct ataaattcca tcgtttgcat
     9961 agtaaatgaa atagggaatt ctgcgccttg aataattaca acagcagaat tttttaagtc
    10021 ttcaacgtga attccataat cagataaccg agccattaac ccgcacctcc aactttagcc
    10081 aatgttttcc actgttcttc atcgtataca ggttgagcaa tgaatttatt aaataattct
    10141 agagaagctc cgtctctatt tgaatcaaaa cttgcataca tcacattatt gtatttcagt
    10201 ccgatggaaa ccagatttgc agttacatcg tcaatttttg tttcttcctc tgcagtggca
    10261 tactcttcgt caatcacatt ggatagttgt gtattaggat accaaactgc ttttttaccg
    10321 ccattttcaa tatttccaat aaatccaaag gcgaagtacg gaaattctcg tgcggtattt
    10381 ttgctaaacg ttactccgct tttagcaact aatcctttga tttcatccat cacttctatc
    10441 ggaataccca cgtgatccaa cgcaagttca tgttttgttt ctcgcgacac acgacgaaac
    10501 attttgctgg atgtccattt ttctaatgct gttccattcc ctttgacacc gatttttgtg
    10561 gcaattggca atcgtaaaac ttcactataa gtcggtgcag ttccaacaga atctggcgtt
    10621 gccatcatcg caattaaaat gtcgtccaat ccttcaaaat aaaaagtatc ttgttttccc
    10681 aattaaaatc acccttccca taaatcaagt atttttctag tcataatttc ttcaattttt
    10741 tctttgtttt gttcatacgt accacttgca aaatgttggg cacgttgatt tgttgtgcca
    10801 ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt gaactttcac ttgatcgttt
    10861 tcaactacta cttttatttg atcgcgcata tgtttctttt ttaagagcga cttaggaata
    10921 ttaggaagca actgctttag ataaaagtta gctgcttctt ctaaagattc caacgataat
    10981 tttttcggat caacttttga aaggtttcct aaataatccg atatttcaga aaaaccattc
    11041 ttattacttg gcattttcca cacacctcac atatgtgtaa tagttggtta cggtatcgtc
    11101 gttctcatca ccttgtatac ctgtaaaatc tgaatatgga atgccagcat tttgcagcgc
    11161 ttgttcaata acaactaaat cctgttctgt tccaagtgta aaaaaagaga cttggtaata
    11221 aggtaatttt ttatagactt taccggatgc catttttttg ctgttactca catttgagta
    11281 cacaatgtat ggatacatcg tccctaatct ggctttgtct ctgaacactg ctaactttgt
    11341 tgatttcagc gctgttttca attcatcaaa gctaatcgac ataagctaaa ctcaactcca
    11401 tttctcttgc atcgggattc gtataaatgc gagtaatgtt atacgttaca gaatcaattt
    11461 tgagcgcact taatttctct gtgatggatt tatcccatct gactttaatt cgtctgacaa
    11521 cgtctgtctt ggcttgctgt gataaatatt tttcttgaga agtcacaccg agttcttcat
    11581 agaatattag acgcttaaat tcgtaaattg tagttggacg atcgtttccg tctgttcctg
    11641 ttttgatgtc tagcaattcg gctttccatc tgagattatt agtctgtctc ttcggcattt
    11701 tgaatcgctc cttgcacgat aaatggcgtc atggcattca tagctttgtc gagttcatcc
    11761 tctgaaactc tatattcata ggcaatgccg gcaaccatca aaataagata ttcttgttgg
    11821 ccaccagttg ctgttttgac ataatctttt gccatattta aataaaaaga gagcaaagaa
    11881 tcatccatgc cctcttcaaa atgaatatgt gatttgaatt tttcctctaa agacaattct
    11941 ttagtttgct cttccatctt aaccaccaac tggttttgta atttcgtagc gatatactgc
    12001 cggttcaaat ggagaataaa ccaattgacc atctagcaag ttgtaaattt ggaatccaat
    12061 ttgattttta ccagagaatt tttcaacaag tttttgaatt tccaaggcac caataacttc
    12121 ttgaatttta aatgcagaaa aatcgccaaa atataaaact ggcgtgtctg gttcaccctt
    12181 tttatctgct gcatctgtcc aatccacagg atagccaact aattggtaac caattccacc
    12241 ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca tctgttttca ttttttcaat
    12301 ggcagtcaaa gcagctcgat taataataaa gcgtcccttt ttcatcactt ctgtcactgg
    12361 tgtattttta aattcgatta atgcatcata taatttttgc ccagcacctg aagcagttag
    12421 atctaaaggt tttttaaatg ctacagcctt tttggctaat gcaccaggat tttcatttcc
    12481 agcgtcatca ccattgaaca tataattgat ttctttacgc acataagctt ttttcaattc
    12541 ttccacaaca atatcttcaa ctggaacacc agacattttt aataattttt tagttactgt
    12601 tgccaaagca tcgaattcgg caggattaag caaaatttca tcaaactgaa tagctgtttc
    12661 agcaatatca gttgaacgct ctttcttgtt tacattcgca tctgctttct tcacaagaat
    12721 tggatatttg acatctcctg atgttcgcac cactgttccg tatttacgaa gtaaattttc
    12781 ttcttgagca taagtaataa cttcagatgc aattacttct gggacagtaa ctgaaccgtt
    12841 gccagcttca atccctaaag ctcgagcttc tgcttcagaa atatttccag ctacaaaatt
    12901 agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg gtcatttttg cacgtgcctc
    12961 caatccgttc ttaattgatc caagtaatcc atctcgttgc tgttgagtaa tcattccaga
    13021 acgattttct gaactatctt cactgtctga atcttcttct tgatcgttgt cttcaccaga
    13081 acggctttcg tctgaatccg tactattcga ttgatcatct gtattgtcgt ctgtttcatc
    13141 agttccagaa tctgcgccta attcgtcttt aattccgttc aattcatcaa taacactgtc
    13201 aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat tctcctgatt caactttttc
    13261 acgtaattca gtcaatcgtt gctcacgacg tgccttcatt tttttcaata attctttatc
    13321 catgtatttt tcctcctacg cttctagcgc ttgattaatt tttttgatta atttttttct
    13381 ttcttcgacg tttttttcta attcatcacg acttcttaat gcagcttctg tatcttcgta
    13441 tgctggcaaa ggcacaatag aaacctcgta taattccact tcatggattg ttcgaagcat
    13501 tggttcagaa ttgtagtccc acgtttcttc agtcggcaca aaaccaaaac tacattggtt
    13561 gatgtctcct cgttccatag atttaactaa gtcccttgct accgttgtgt ccggtaaatc
    13621 aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga agggttccgc ttttagtacg
    13681 tcctagcaca ttggaccaat cgtgattgaa caaacaacga acatccgaat tactaattgc
    13741 ctttgagaat gcaccaggaa caatcacttc gcttaagtca tcccataaaa gtgtttgact
    13801 gttgaataca gcagcgtagc cgctaatggt cctcgtatga gtttcttcat cggaacgtgt
    13861 tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc ttcatttcca tcacctcctt
    13921 tcaagtcttg atcattcgtt ggtaaggaat catctgttgc atttttctgg ccaatcctag
    13981 ataagtcatt tgaaatatag atagcttgtg tttctggagt attctgttta ggaaaaccaa
    14041 gcatttctgc cacgttatct ggacttgtaa tcccggtacg aacgatgttg tagccaatat
    14101 ttgtttttgt tgagtaagga acaaaatcca aaatattaat tttccattcc actctatagc
    14161 cagaattagg cataaaaaaa agagcggtgt aatgttcgct cttgtttttc aatattggtt
    14221 tgattgcttt gttgtgcaga tacatcatcg ctttttcaat atctgtcttc atcagcgatt
    14281 gatacgtatc aacattgatt cctagaaatt ttcctaagtc ttttttgtaa acacctaaat
    14341 aattcaaaat tgccgcgtca tcaacaggac tttttaatgt ctcgatggaa tatccttttc
    14401 ccaaaggaat catcttaaca gaatgatcac tctcattttg cgttccttcc agttgatcca
    14461 atatagcttt gacaattttt gtttgggcgc tattatttgg attgatgtgg gcgtctagtt
    14521 taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc cgtcaaaact ttttcagcgc
    14581 tcagaacgcc ttctagagtg tttcttgcaa gatcaattat tccagcacct tttaatgaat
    14641 cagttccgat gttcttaatg tgtcgaatca tttgaccagg tattttttga ccattcattt
    14701 caaattcttc ttgaagtcgt tcattgattt tagttgttac accgtacgcc aaatgaagct
    14761 gatccctatc cgttaatggg aatgtctcac cattgatcaa taaagtattt gtttccaatt
    14821 tggtaaattc gaatcctgtc aaataatcat tgggactctt caaaatattt agtaagtgat
    14881 gatctttgac ttcgttgccg tcgggaccaa taacaattgg tgtggccaat gccacctgat
    14941 tagatatgtc ttgaactaat tcataaacat cagaagattc catgatagat gaatccgtca
    15001 catatctttg accataacgt gtgtagtgtc caaaaatatc ctcgatatat ccacgttttt
    15061 ccataaaaga atagactgca ttcgataacc gatcacgtaa tttcaatttt tttcaccgcc
    15121 tttctattta tctatagatg gaacttaggt aatcatctaa ctcatctgaa tcaatatctg
    15181 tcatttgatt catcgtttcc ttatgaccac acaaaaacgc cacgaaccca tcaatctttt
    15241 tctttgattg acgtttactt ggcgcttttt gtccattgat gttagtaatt gctacaacgt
    15301 tcaaagtgca ataaaggaat aatggattat caaattgaat tcgtttctca taaaacaacc
    15361 gttcgacatc gtcaaaagga gcattcaata ctttaggata ttgagcaact tcaacgcatt
    15421 ccaatcctaa gttttctaat ttctcaacaa gtttgtcact catcgctgga tcataattca
    15481 cttgctgaat atcatataaa ttcatgcagt cctctatgta ctgcaaaatc tgatcttgat
    15541 caatcatttt tccgtcgcaa aattcaacga aaccttgttc agccaaatca ctgtaaggaa
    15601 cattatcttc tttttctcga aactctaaat cttcattcgg aataaaataa agttgcttta
    15661 ctttaagaac cgctttacca tcttcatccc atgttgggaa gtttaaagat acacaggtca
    15721 aatctcgtgt acgtgataaa tctaaaccga tataacatgg ttcgccactt aaatcaccaa
    15781 gttcttgtgt ggtaactaaa catggctcta cttgatcctg ttcaaagaaa ttatccgcgc
    15841 cgttcacaaa tacatccaag tgtttcgtta gaaattcagc tttggaatga gctgaccgtt
    15901 gcgctgtttt aaatgccgat tctaaagcag ataaatcgac tgatattccc cagttaggat
    15961 tgcacatttc ccagactttt ctatccgtcc aatcataatt tttatttggc tcatagatta
    16021 gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc ttttgcttcg cgatatacac
    16081 gcattccaac agacgacgaa cctttcccag cagttgagat attaaacatc aatggctgtg
    16141 gtaaagatat ctgagcagac ttaaaattgt catactgttc cattttctcc tgtttatgca
    16201 attcatcgtt caatacaaaa tatggattgg atccctcgat attatcaata ttcttggttt
    16261 gaacaataaa tttatttgag taagccatat cttcatgaat atagtcataa gtaatactag
    16321 aaacagttcc ctttggcccc ctaaatattt tagttccttc aagtaggatt ggattgttta
    16381 agattgtaac tgcaaaaggt ttggcagcat attgcgcttg agcaaaatca gatgcgcaag
    16441 catagcaatc aactgataac gccccttctc cgtacattgc atatcctaat gaaccgacag
    16501 caatcaatgt tttaccattc ttttttggaa tctggacata agcctcacga gtaacgcgta
    16561 caatttggcc tttttcattt tctttaaccc aaccataaat ccaagaataa ataaattttt
    16621 cccagggttc taaaagaaac ggttttccca ccatttctcc ttttgtgtga acaataaatg
    16681 attctaccca atccatcatt tcattcgcgc gatctacatc aaaccaaata tcttttcttt
    16741 ttttccactg ataccagcga tctattgcta aacgaacggt cttaggatac ttcttaggtt
    16801 tctttcttac ttcttttgca aataaatcag cataatttac accaggttca atcatttttc
    16861 agcacctgcc ttcttacgcc atttatttct gtgcgctgct agttcatcta ctggctttac
    16921 ttctgggcgt gtaatttctt catcttttct tgcggtcgat cctccagcaa ttagtctacc
    16981 agtttttgct ttgtttgtta atcctaataa atctagagct ttcatcttct tatctgccca
    17041 agtttctact tgttgtgcca atggatgttt tgattgatta gtagctcctg atttattcgt
    17101 gaatttttgc gtctccggaa atcctttttc cttccacaat aaatatttgt gttggtaaat
    17161 ttcaaaaata tccaagtatg attcgattaa tggatcaaga gtgatggtgt acaaatcaga
    17221 caaattcatt atttctaaga tacgagcttt ttcagcactt actttttcat caataatcgc
    17281 tttacgttgc gctttagtcg tcatttttgt atacaccccc ctttgttttt tgaaaaattt
    17341 gacctaacga tgcgcgtgac tccccgctac cctatctccc cacgcgaaaa aattttgaaa
    17401 atgaataggg gggcttcaat tgaaatacga aggaaaaact tttttgtctt ccgtttcgtt
    17461 ttcaacaatt ggatgacatt ttgaacataa tagcatgaga ttgtttggat caagcttaag
    17521 cagttcgttg tctttgattg gtacaatgtg atggacgtgt gctctctttc caaatatgaa
    17581 ctgaccacac cgctgacaat gaccaccttc tctttcataa ataaattgac gcatatcttt
    17641 ccatgcttgc gttcgataga atggtttgtt ctcatgatga taaacagact ttgcttgctg
    17701 cttcttcttg cgtgatctgc ttgatctctt gtgttcagta cagtagatac cctttgctat
    17761 tttgttcgtg catccgtcaa actgacagta tttcattcta cttcacgaat aagatttatg
    17821 atatcgcctt ttgcacggat agcaccagga atatcaatac catgtttctt agcatatgca
    17881 cgcaattctt ttgcagtcat attgtccagt tcatccgtat cttcagtgga ctgatcatta
    17941 gtagcttcgt ctccatcaaa attagcagca gtgtttccat cgctatcaag aatttcactg
    18001 ctatgagcta tgagttcgcc attgacagca acaaatgatt tgccatcact caaaattcct
    18061 ttttcttctt ttacttcaaa atttggttct tgatctttcg gaacaactac tgtccttttc
    18121 ttttctgaat cccaatactc tgttccacta atggatgttc taattttgat cattgccatt
    18181 ttaattctct cctttgtaat ttgtacggat tacttttgcg cccattcgct cataccattc
    18241 aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa gaaataacta acgtattcat
    18301 tccagttctg taatcatcat tctccacttg cacatgtgca tgattaccat tccaattttc
    18361 tctgtacgga ctattctctg cttcaattgc tttcttataa actttagcca aacttgattc
    18421 tacttcaata ctaagtaccg cttcatgaaa atcattcatt tgtttactct cctatcagat
    18481 attttgtggt atgatttata aaaaagatgc gaggtgtttt aatgcttcaa gaggttaata
    18541 ttaagtatcg tgatcgtcaa aatacagaga caatttattt gccaaatagt tgtccgcatt
    18601 gcggaaatat aatgactccg tatgtgtatt ttggggtttc atcatatagt gcgttcgata
    18661 atgatagaat ctttggcgta ttagtacagt gtataaatga tgagtgcaac aaattttata
    18721 gtttacaatt tataaatacg tttaatgaag atgaaggata ttctgaaaat attttaatta
    18781 aagattatta ccgtccgccg attaaaatag atttaccaga aaatattgaa aaagtttctc
    18841 ctacatttgt tgatatttat actcaagcca cacaagctaa atctgagcaa ttggaacaaa
    18901 ttgctggagt tggttataga aaagctctag aatttctaat taaagattat gcaatatcta
    18961 aaaattcaga ggatgaagat aaaataaaaa aaatgttatt aggtaaaaca attgaaaatt
    19021 atttgaatga ttttcctaaa ctccaaagat tagccaaagc tgctacttgg attggtaatg
    19081 atgaaacgca ctatgttcgt agacatacta ataaagatgt tcatgatatg gatgcattta
    19141 ttaaatcagc agcgcaattt atcgcggctg attatgatgc tgatttagct gatcaattta
    19201 taaatggaaa taactttatg ccaactacta attaaaagaa taaaagagcc acagatacca
    19261 attaataaaa cggttgggat atcttggctc tttcatattt ttttgacact aatagaatat
    19321 catgctgcta acaatgttta catagctaca atgaccgaac atttagtgaa cagtgtaatt
    19381 ttagaataaa gagagttgtt ctttgtactt ctcgctattg taaaaatcaa tttcgttttc
    19441 ttttttcaat cggtcagctt gtctgtgttc atactcatct aaaaagttca atgtctttct
    19501 aatttctgca tgtcgctgtc tgacatacga tgagctatac ccaacagatt cagcaatatc
    19561 ttctaagctc atttgatcaa catatttcat cttaacaatt tgattatcga taccagaaaa
    19621 gctatctatc agcaataaca tttcttcttt ttgctcgatc aacaattcca attcattttc
    19681 tatcttttgg atattctctt ctaaagaaga agttctcgaa ttcttttcga tgcggacgtt
    19741 tgctaaatca ccacagaccc atcgattcaa ttcaagctta cttttattaa gattccactt
    19801 taagtaaaga atctgctcat ctagttcttg gtaatctttt aaccaatgaa atctcacaaa
    19861 cgccacccct tatggtagaa tagtattgcg ctgctatctc gaaaggggta gcttttttat
    19921 tttttcttag ccgttccatt ctggattgcc ttttgttcca aacgtcgttt tttcttctta
    19981 atctttgatt ttgtttttcc catacaattc tcctttccga aaacacattt tgttcgattt
    20041 ttaatactaa ataaaagttg gccagaattt ttcgttcgtc tttactcatc tttttttgaa
    20101 taagattact agcataaaaa tagttagtac cacgaaaatg aacaggtaaa tcaattacgt
    20161 tcaccttctt catgccagtt atcagccact agaatctttg cgttagtgcc gccaccgttt
    20221 tcttttttgt atttttcaaa tgctttataa gcagctgttt ttgatttata gatttttccg
    20281 gaaccgactg ggaacatcca tgtgccctct gtgatagcta agatgtatac tttcatttaa
    20341 ttcacccctt taatccccaa cactacatat ccggacttct gcatgtaatc agtaatataa
    20401 gtgatctctg ctttgtatga gtcaccagtg taactaaatg ttggtctcgt tagtccaggt
    20461 aattcatgtt taatgtattt tttatattca cgtagtatta actgatcacc aactttgaag
    20521 tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc tcgtcactgc ttcaaaatat
    20581 tctggtagta tttttagttc gtggatcatt ctgtttcctc cttcaaaatt cgctcatcat
    20641 caaaaagtga atctccacaa aatccttctc ccaaatattt atcgttcatg tataagtcaa
    20701 ccaaatattt gtgatctgct tctcgatatt cattaatatt aacgatcttt attttgtaaa
    20761 cattaccttc gtcgctcact atcttgaatt gttctctgac tttcaccacc gttcctcctc
    20821 tttttgaaaa aattttagtg tttttgtaag accccctaaa tcagcttttt tatttgatat
    20881 aatacttgta tcgattaatc aaatcgaaat taaatttaaa aaggtgattt atcatgaata
    20941 tcaacaattt agtaaaactc gttgaacaac gttttaaaga atcaggatta gaacaattaa
    21001 aaaaagataa ttctccagaa ttattttcta attttaccga agacgacatt cctactctta
    21061 aacaattaaa atattattct gattattgga cgcaaactcg tgagaatgaa ttaaatttag
    21121 aaaaactcat tattaaaaag aaatagcaac tccagcccac acggctggtt ttttagtttc
    21181 aacttccctc cttacgggtc aaaatcatcg gttccggcat aatctgatca tcctttagca
    21241 acaaatcagg atattttttc cttagcttct tattgttcgt gtaagttttc aatagccatt
    21301 ggttggcttc gcttttgctt tctccagaaa aataaatttt ccctgtttgg atgcctgcaa
    21361 gttgaatcat cattttcacc tcaaatcaaa tttttttctg ctagatggag caaaagcaat
    21421 ccgacatcaa gaatcttttg acccattatt tcagctactt tgctcggctt aactccttga
    21481 gaaaagagca agcgtgcttg ctctatctct tcgtgagtcc aaataaattt ggcttcctca
    21541 aggataatta ctggatcagt tgctctcatt gttcctctgg aaaaatgatg tcattcttat
    21601 gcttggacca ggtatctgca tatggaacaa agtattgtct agctaattcg atttgatcaa
    21661 ttaaagcagt ttctgataat tcatggtctg cagcaatttc attcatacta tcgccttcat
    21721 ctaaacagat aagaccgttg acgttatcga tttttacatt tgtgactgct tgactttctc
    21781 cacgctcata atattctaca gttgatactg atacatcagc ttcggagttt aattgcagaa
    21841 tctgttactg ccgggataat ttaatattct tttcataatt cacctttttt cctactgaca
    21901 tcgaatattt ttcatgttat gattagccgt gaaaggagag ctatattatg tgtttacaca
    21961 tgatgtcctt agctcattcg gttctttgga agcttttttg gaaataactc tcaggttctt
    22021 gacgcaaatc tcatttattc tttgaaacaa aaaacttcca ttttccgaga gctttggatc
    22081 acttcaaaag agatttgcat ttatatttct gtgaccttga gtcgcgtaaa gaaccttaca
    22141 gcaatggcgg caattccact ttcaggaaac cgcctttttt cattgatatt ggtggttagc
    22201 ggactaccca ttttctttcg gcagtgccaa accacaaatg atctgtgttg atgtttaggt
    22261 agttgtatac cagataagct aaatccaaag tgcctgcatc ttcaagacga caatattcca
    22321 aaaattctcc catagctgga cataaaaatc ctggagctat catatcccaa cagttaatag
    22381 tgcaaagaaa ttcgtttagc ttctgaacgt tttctttggt ttcacgaatt acaacatact
    22441 ccaattcttc tccgctggca gagcattcca aaacttcaaa ttgattaaga aatggtagaa
    22501 catatgcttc aaacatcaac attccatctt tctgtttttg cacttgtttt gcatcaatca
    22561 tgtctatcct cctattcagt tatttcttcc attaatggaa ttatttcagg tcactggact
    22621 taacgaaaac accattgacc atctttccag tccgaccttt gatttcgtca taagcaaaat
    22681 ccaagcactc gtataaatcc atatcatttt gcattgccaa gatgatcaag gttactacta
    22741 catcgccaat tccgtctctt aaaccatgtt catcttttct agctagagaa gcggcaactt
    22801 ccccgatttc ttcgaccgtt tttaacattt gcttgctgaa atccgcttga tccaatccct
    22861 tatcttttgc ccactgctct actttcgcga ttagttcgtc cattatttct cctccacata
    22921 cctaaactgt cttccttttg aatcaatcca taagctccta gctctatccc aaataatatt
    22981 tttgctcaga ccagtaattt cagataactg tttagcggta cccgttacta gaattcgatc
    23041 accatgccag attgcaatct ttctcggcgt tctccgtttg ggcttttcag tccacattga
    23101 tttaccgagc ttttggactt ctgcaactat ttttttatct tcctgccaat cttctgaata
    23161 agtcaattcg ataattcgct gcattgccgc tttcttatcc atcccgacat tctcctttca
    23221 gtaatttgag tacttgatca agtgcgctct cacgtccgcc atgaaatgtg ttgagccact
    23281 tgtcttcgta cgacacactt tgtcttaaag cttcttgatg cattaattcg atctgtgctg
    23341 taaatgtctt taggtccatc ttgtttacac ctgctcaagt tcattaagat gtttttgcaa
    23401 gcctttaaca caatcaatga atagtaattt ggtatatgct aaatttctta attgcgttcc
    23461 atcgatatag agtgcgaaat agtatctgag tttactccaa ctcgaacgat cattcttaat
    23521 tccttcaatt ccagcttctt cgagttgatc atatacgtct ctcaggacgt ctaattcctc
    23581 gcccttttta taattcgcta tttcattaat tagttctaga taatcgatct tcatttttcc
    23641 acctcttaga atggtgcttt tgattgtcta ttagctcgtt ctagcgcttt tttcttgaga
    23701 taggcttctt ggtcgattgc ccattcagga agcttctctc gtcttcctgt gcgcttgtat
    23761 ccactgcttg cgttcttagg ttcacttttt tctttccttg cccaacttcg aatagttgcc
    23821 aaatagtttt tataagtctt accagatgat tcacaatact ctgacagtcg ttcgattcgc
    23881 tcttggtaat cattagggaa ttctgttttg agtttctcca tctgctcatc tgacaaaaga
    23941 acatttttat actctccgta tttatgacgg acgggcttag ccttcgattt tttcgaaggc
    24001 ggtaactctc ttatatattc ttttgtatta ttaaatgtat tattaataga tgtattatta
    24061 tctttgactt tttcgtcaat aggggtattg cgtttttcgt caatagggta ttgattaatt
    24121 cgtaggtacc tattgattat ttgattggta ccctctttgt aaatgatttc ccgattcaag
    24181 tatccaaact taatcaaatc acttacccat cgcgatatgg tctctttatt cacaccatat
    24241 aaatctgcaa agtactcatt gcctgcccaa caaaagcctc tttcattaca caaggccgtt
    24301 atctctccgt ataacaactt agtatttggt ttaagtcttt tgtcgtacct tacgttggct
    24361 ggtataatcg cataataact tcgatgttct gtcattttta ccctccaata tttaactttt
    24421 tgattgtttt ctggtttaat ttgatccctt tgatttgata tttatttttg aaattaatca
    24481 cacctatttt gtgcttctct gtgtgatgga ttctgcagag tgctgcaaat gtgtactctg
    24541 catgatcaac ttctttgcgc tttcgtcttc ctagcgcttt gtcaaagtga tcgatgtcag
    24601 ctcctgtttt gccacagatg cagcagactc tttttgtgat gcatttgtag aagtaatatt
    24661 cttgattcgc aggtaaaatc tcatagcctt ctttgaaagg aatatgatgt tcaaagatga
    24721 aatctaagat gatatttgct aagacattgg catcactcac agttgtattc gattcgtctt
    24781 tcaggcttat tttgcgccct gtgacacctt caaaacgaaa gtagaagaat tccttccaga
    24841 agtccgttgg catgcctgta tcgataaaaa tatcgcctat cagcgcatag atgaagtttc
    24901 gttgctgtac ggtgaaacgt ctaggatcaa taaaacgaat ttcaatgact cgatcaccat
    24961 cgtagccgtc atacatcgtc tttagtcgat caatgttcac ttcctcattg atggttgcgc
    25021 ttatgtcttt tcctttgaac tttttcagaa ccgctgaata tgaatcgatt aatggtttaa
    25081 acactcatat cacttcttat ctaattcttt tctcttagct gctattgctc gctccatcaa
    25141 ggcacattgc tcatagctta actgttcaat agtttcaacg ttatcagcta agagccctaa
    25201 tttatctgtc tgctcattaa catattcgat taaggttttg gtcatatctt tacccatctg
    25261 ctcattgaaa gcttctagaa tcgtctctag catgtttaat ttctttgtat cgattctagg
    25321 tggtgttgga atatcttccc cttgaaatac atataatccc agtccgtgta gagccaatgc
    25381 tttcacaaag catcgcttca atgagttatt gatttgcatt gcatttggtt taacaactgg
    25441 ttggtttcga taatctaaaa caggaaataa ttcggtttcc gtgtgtcctt taaccgttac
    25501 tgagacagat acataagtcc cagtttcatc cataagaaaa ggtttatatt cctcaacaag
    25561 aaagtcttga tgagttccag aaacaaccct gtagtgtttg tactcattaa tagttaccgt
    25621 tgcctgtgga tcattctttt tcataatctc ccacgcgtga gcccaagata aataatcaaa
    25681 atttcctttt ttctcgagaa ttttatttaa cttacgacta aaaagttttt caaagttcgt
    25741 tgtccctttg atttcactca tcaaattctg cctccatttc agcaatgtat ttcttacctg
    25801 gtccgtaata agagatatca atcaagttat ctctgtcgta ctcttctagc gcatcaatca
    25861 agccatcttc gatgacgtaa atatattcag gtttattcga atgcttcgat agatggataa
    25921 gataaacatg atcccaaata gttacatggt tgcctaaatc atcttgatcc caagctagtt
    25981 cttcattcgt caaaagattt cgtctgattt ttcgaccact tgtttcctca attttcggct
    26041 tgccccaatc aggatcaatc aaatattgat ctagagtgga aagttctttt tccatatgct
    26101 aaaatctcct tatgatgtgt tttctttgtg actctttgct tgccggcgga gtcacttttt
    26161 tatttgttgc catgcttttt gcttgtcaat atgttgttgg cttaggatga ttggtttata
    26221 gtatttccac cagcaattag caattgccgt ccctattctt agcgcttcag ctctattcat
    26281 tgtcatcacc aaaaagtctc tgttgtctgt tcagttgatc aatttccata cggatcgcag
    26341 tttctggcaa ccacatttca ataaatgaaa cagcatcatc gaatctctta cgaggtaact
    26401 cgccatatct tgggattgaa aaggtacgtt taaattcaga ccaaaatttt gagaatactt
    26461 ttttgctgat ttcttcataa gctcggcttt cttttccccc tagaactccc ataactttca
    26521 tatttccttt ttgcttaatt tcaaactctt gttgtccgct aattcgcata gtatctttaa
    26581 gcatggaaac atctttttta acatctttca tttcttctaa ttgatagatc atcatatctt
    26641 caattgtttg aggaacagta ttcttgcgaa taacatcttc catttcgttg aatgcttcaa
    26701 tgtatttttg tttgaagtag atagctttct ttcctgtaaa ccccatagcc agcaagaaaa
    26761 atccatctct actaatgaag aaaactcgtc gatttctgcc atatgaatct ggttcattac
    26821 cttctacaaa catctgtcca aaattggaca catctttttt tagtgcatca atatctctta
    26881 aaacatgttg atgttttttc tcgaagcttt ctgccacttg taagctcgta gtcacagctt
    26941 ctttattttt caaaattact aattcttgca ttatttcttc tctccttttt ggtataattt
    27001 agttaaaaac tggtggtgtt tattttgaat ttttttcact taacaatttt tcaatggatg
    27061 tcaataataa gttttatatt gagtacgttt ttaacaggga taaaaataaa aggaatgcgc
    27121 cctcaactag aagttgaact taatgcttct tacttcgctg cagatatgat ttatacaaaa
    27181 gtaatcattt ctaactattc aacagaacca gctatgttag ttaatttaga actttcatcc
    27241 gctaacttaa accgcagatg gtcagctact ccatttaaga aattaattgc taaaggagga
    27301 tcagtcgatg ataatagaat atactctgaa gctgtaccgc taaatattcc tcctaaaagt
    27361 gctatatctt gttaccttgc atttgaagta gggaaaatta attttaataa actccttaat
    27421 caccaaacaa aaatgatatt tactctaaat agaacccaaa tccacaaaat tgttgatatc
    27481 aaaaatacaa acttcccaat agagaaatta gtgaaagaat taaactgagt aatagtaata
    27541 tacattctag tttctctttt ctattcattt ttagtcagcc ccctcggttg gctttttcgc
    27601 tctgtactca gcttcagctt catcaagccc cataaaaatc caaaccatgt aaacaatcgt
    27661 tcctatcaac gcttgcctgc ttccccaaag tcctaaagcg tagatgatta gcggtgcgct
    27721 gaacactagc gctctattaa attttcccat ccgcttgcct ccttaagatt tccgaaaaat
    27781 ttgtttctaa aaattcaagt gttttacttc ttaaaaatag atatgtgtct cttccttcaa
    27841 ctggataata gacaaatcca tttttgtttt tctcgatatc gataatattt ctatatcttg
    27901 ggttctttaa aactctagaa gtaaaccaat catattttct gttaatccgt tctagcactt
    27961 ctggcaacgt catccatcta ccagtatcat cagctttttt taactcctca taatccactt
    28021 gggagataat tacatagcct tctggaattg ggatttttgc ttctagatat tgcattagct
    28081 gttcctccct ttacaattcg tacatagtga taatcgaatc tataattctg tttgcttctg
    28141 cagaagtctt tttaccgttt aaaattaaag ataagtagct tttgctaatt ccaaatcttt
    28201 cagcaagcat ggtgtaagtt aagaactttg aactttcgac atattctttg attttttctc
    28261 tatctcgttg agtgatttct gcaatgtcag tcatactaaa actcctttct aaccaatttc
    28321 ctctaaatcc atttgagggt aatatccttc tttttttagt aattcgtaga taaatagacg
    28381 ccctttctgt gtccatttgg tattcattac aattttagtg ccaccatcgg ctttcgggat
    28441 ctcagttgta tgagattttg tgtatccttg gttcatgtgt tttttgcaca ataaccattg
    28501 gttaccgact tttttctgaa tacctagttt atgaagtaat ttattcatct gttgtggaga
    28561 catcccataa tctgctgcaa tctgactaat tgttactgaa tctgtagaag ataatatgct
    28621 atctaaatag gagattttag gttcgtactc tgcaatcttt tgttctgcga ttaatcttcc
    28681 agttctttct tcttttagtt gagttgctaa ttgaatgatt gtatctggat taagcaaagc
    28741 ttcttctact ttttctggag ttagataacc tccatgtttt ctaattgctg gcaacacttc
    28801 acttgttacc caacgtttaa attttttggc agagggaagt tttgatttta agattaaact
    28861 gtacaaacca gattcgttga tgattgtcat ctctcttgat tgacctgagg tcgtgattcg
    28921 cgaccccatc ttatcttcca aatctacatg ccgcgacaaa gcatctttag tgtttgaata
    28981 acccaaaaca ctcgcaacgt ctttgcctac aaaatatggt tcatcattta ctaaaattgt
    29041 ccgaacttcg ttttgttcga aattaaaaat ttgcggtgtg ttcatatttc tcattccttt
    29101 cttttatatt cgtaaacaaa tttaacaact tttttctaaa ttcaattgac agtatctgag
    29161 taatactcta tactaagagc ataattaaat aagacataaa aacattgatt ttaaagcttt
    29221 cttggcggtc tgcatttaca tatcaatagt gttttttgtt gtctttttag ttgttaaatc
    29281 tgtttacaag atatagtata gctcattact cagaattagt caaattattt ctgcgtattt
    29341 ttctaaactt tttttgtaaa catttagaaa ggttgtttta tcgatgaata cctatgaaat
    29401 aataaaagac ttggcgaaga ggaaaaagat atctatacgg cagttagaaa ttaattttgg
    29461 atattctaac ggttatctag caaagtggaa aaataatact cctaattcag atgaattaag
    29521 tcggattgct gactatttcg atgtctctgt agactacctt ctaggtagag aagaaagaga
    29581 aacccctaaa catgtggatt tatcagaaga cgatactgtt ttttcttttg atggaaaaga
    29641 aatatctaag gagacaatgc gtaaagcgat tgcaattgct aaagctttag aggaaaatga
    29701 atagttggag tgatggtttg tatgtatttg aaattgaaag aaatgttgag cgaatacaat
    29761 ttgaaagtag tttatatgga gatgaaagag cctggtttct actatccaaa acccagaatc
    29821 atttttttga atgaaaatct atacggtgaa actgcagaag cctttcattt atctcatgaa
    29881 cttgcacatt tcagcgcctc tcattttgaa ttttcagttt tgtacgatac ttctacaact
    29941 tttcactcaa aatttgaaac agaagcagat aaaatagcta ttctaatttt attaaatatc
    30001 tatattgaga acgaactgac tgatgaatct cagtttaatc tcgaaaaatt tatggagtat
    30061 tattctattc agaataagct cagatacact tgttatgctg tctgccaatg ctattttaag
    30121 aaaaaatatt cttacgcaag gcaatatgta tgaatacatc aagaattatt aaaaaaaccg
    30181 atttcagcaa aacattaaaa aagcccgtgc tgcaacacgg gctctttcct catatatgag
    30241 cttctacaaa aaaaatcggc tctttgtcaa taaggactga tgggttgtac aaaatcaaat
    30301 ctgggtcaga atgaacctca ttctgg
//
LOCUS       DAFEML010000029        29110 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFEML010000029
VERSION     DAFEML010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.029"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1031)
                     /locus_tag="LP468_001500"
     CDS             complement(<1..1031)
                     /locus_tag="LP468_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081043.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFATSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="LP468_001501"
     CDS             complement(1113..1802)
                     /locus_tag="LP468_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2081044.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="LP468_001502"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="LP468_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL2081045.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="LP468_001503"
     CDS             complement(2329..2832)
                     /locus_tag="LP468_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL2081046.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="LP468_001504"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="LP468_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL2081047.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="LP468_001505"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="LP468_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL2081048.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="LP468_001506"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="LP468_001506"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL2081049.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="LP468_001507"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="LP468_001507"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL2081050.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="LP468_001508"
     CDS             complement(6444..7463)
                     /locus_tag="LP468_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2081051.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="LP468_001509"
     CDS             complement(7636..8541)
                     /locus_tag="LP468_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2081052.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="LP468_001510"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="LP468_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL2081053.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="LP468_001511"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="LP468_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL2081054.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="LP468_001512"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="LP468_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2081055.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="LP468_001513"
     CDS             9754..10398
                     /locus_tag="LP468_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2081056.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="LP468_001514"
     CDS             complement(10454..10957)
                     /locus_tag="LP468_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2081057.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="LP468_001515"
     CDS             11554..12519
                     /locus_tag="LP468_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2081058.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="LP468_001516"
     CDS             complement(12618..13790)
                     /locus_tag="LP468_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081059.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="LP468_001517"
     CDS             complement(13777..14922)
                     /locus_tag="LP468_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081060.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="LP468_001518"
     CDS             complement(14936..15868)
                     /locus_tag="LP468_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081061.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="LP468_001519"
     CDS             15985..17064
                     /locus_tag="LP468_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2081062.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17690
                     /locus_tag="LP468_001520"
     CDS             17061..17690
                     /locus_tag="LP468_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081063.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17800..18027)
                     /locus_tag="LP468_001521"
     CDS             complement(17800..18027)
                     /locus_tag="LP468_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2081064.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18130..20718)
                     /locus_tag="LP468_001522"
     CDS             complement(18130..20718)
                     /locus_tag="LP468_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL2081065.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20738..21397)
                     /locus_tag="LP468_001523"
     CDS             complement(20738..21397)
                     /locus_tag="LP468_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2081066.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="LP468_001524"
     CDS             complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="LP468_001524"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL2081067.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22170..23036)
                     /locus_tag="LP468_001525"
     CDS             complement(22170..23036)
                     /locus_tag="LP468_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2081068.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23145..23786
                     /locus_tag="LP468_001526"
     CDS             23145..23786
                     /locus_tag="LP468_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL2081069.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="LP468_001527"
     CDS             complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="LP468_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL2081070.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25227..26126)
                     /locus_tag="LP468_001528"
     CDS             complement(25227..26126)
                     /locus_tag="LP468_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2081071.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26128..26925)
                     /locus_tag="LP468_001529"
     CDS             complement(26128..26925)
                     /locus_tag="LP468_001529"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL2081072.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26903..27607)
                     /locus_tag="LP468_001530"
     CDS             complement(26903..27607)
                     /locus_tag="LP468_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL2081073.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27738..28313
                     /locus_tag="LP468_001531"
     CDS             27738..28313
                     /locus_tag="LP468_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL2081074.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28431..29108
                     /locus_tag="LP468_001532"
     CDS             28431..29108
                     /locus_tag="LP468_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2081075.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8566 a         6169 c         5231 g         9144 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagt cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcta gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg
    17221 acatccgcat gcctaaacaa acgggcatcg atgctgccaa agaaattttg gctaaatttc
    17281 ccaaagccat ccttttgctt ttgacgacat tcaaagatga agaatacatc cgcgaagcat
    17341 tttccatcgg tgtcaaaggg tatttaatca aacagaactt gcaagcgatt attccttctg
    17401 tcaaatccgc ttataatgga caggccgtat ttggtaatga aatcatcgag actttcactc
    17461 aaatgatgaa gaataaaccg acgattgata gtcatgctta tgcttctttt agtgaacgtg
    17521 agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct
    17581 tgtacttgag tgacggcact gttcgcaatt acatcagcca attactagaa aagctagatt
    17641 tacgggatcg cacgcaattg gctatctatt tttatcagca tttgcaataa gtcttatcta
    17701 acacaaaaaa acctgaatga tgctccttcg catcattcag gtttttttca catcttctat
    17761 tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat caaggattcg cagggctgcc
    17821 aggattcgtt ggattgttcg gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt
    17881 ttctagtttt gattcttcac gatcgtctcg ttctacatca ggactttcat tcaatttgaa
    17941 ttctttttcc atctcatcta actttttaaa gtcattgcca gattcttttg ctaatttcgc
    18001 taatttatct tcggtttctt tagccataaa gtaacgcccc ccttttgatt tcagcttagc
    18061 atatcacact gaaaaaacaa aagaaaacgc taaccaacga tcatttttag ctatttctca
    18121 tctttaaaat caagcatttt ttgccggtat aaaatcgtag ggagaactgt tttccatacc
    18181 aatcatcgga tctactaact ggttatcgat cacttctgct gtaagaacga aatctttaga
    18241 aacagcaggt tctacctctt ctttcttttc ttctccaaca aatgaagaaa acagatctgg
    18301 ttccactgtt tccattactt ggtttttcgt ttcattcgtc ccactgtcat cttctacagg
    18361 tagcttttct tttacaaccc gtggctcttt tgtatagttc ccatcttcaa atggatcatt
    18421 tccgaccaaa gaatcttcat aagctgctag tttggtccgg agagtgatat tcattttatc
    18481 attatccatg atccttgatt tcaacgtagt catccggctt gctgattcat tcgctacaca
    18541 agtgacatag gcttgctctt cccctaacaa aatcaacagt tccttactgc gagtcactgc
    18601 cgtgtagagc aaattacgct gaagcatccg ctgatattga tggaccatgg gcaaaataac
    18661 catcttgaat tcactgcctt gtgatttatg gattgagcaa caataagaaa gagtgatttt
    18721 attccattcg tttcttttat aagtgacctc atttgcatca aactggataa ctaattcatc
    18781 cactttatct tcagaatctt ttgccaagat gatacccgtg atttctccca tatctccatt
    18841 gaatacattc aattcgggag tattgactaa ttggaggact ttgtctccta tccgataaac
    18901 ggtgtcgttc caatgtactt ccttttttcc aggtttccct ggattgaata tctcctgcat
    18961 cattttattt aacgcatcga tccctgcagg tccccgatac attggtgcta atacttggat
    19021 atcttgtgca cggaatccct tatttttcgc tttttccaca attttagaga tcaagggttc
    19081 aatttgataa gcatcacttc ggaaatagga acgatctttt tgattctttg tgaaatcttt
    19141 tggcagacgt ccttctttga tctcatgggc aagaggaata atactagaac catcaccttg
    19201 ccgataaatc tgattgagtt ccattttggg aatttgttcg atttccaaaa gatcatggag
    19261 tacttgacca ggaccgacag agggaagctg atctttgtct cctactaaga taacttgcat
    19321 attcgtcgga atcgctttga ataatgtgtt agccagccat gtatcgacca tagacatctc
    19381 atcaacaatc aaaagtccgc cttctaattc tttcgtactg actgaaggtg ttttttcccg
    19441 tccattcagc cccagaagac gatggatcgt actggcaggc agacctgtcg tttcgttcat
    19501 tcgtttagct gctcggccag ttggtgctgc aagtagaata ggaaaaattt cttgggtata
    19561 ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa agattgacga ttccgttgat
    19621 cacagtagtt ttccccgtac ctggtcctcc tgttaaaata aatagagggg aacggattgc
    19681 ttcagcgata gcttgttctt gcgaaggtcc atactgtatg ccgaatattt tttcgatacg
    19741 ccgaatattc ttctgcactt ctttttcagg ataatggatt tcttttttac gactgagaag
    19801 gcgctggatc gaattaccga tcccccattc agaaaagtac aaactgtttt cgtaaagatt
    19861 agtctcttct tgttgtatct ttccttcttc aacaagttgg ataattacag tagcaacctg
    19921 atcaggctgg atttcaattg ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa
    19981 tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa
    20041 gatagctgct cgaattcttc tcggtgaatc tgctgcaata ccgatttgtt cggctagatt
    20101 atctgcacgt ttgaacccga ttccttctat gtcttcgact agctggtacg gattttcttc
    20161 gatgatatcc aaagactcgt tcttataggc ctggtagata ctgaaagcta actgactacc
    20221 gaacccgtaa cgattcagtc ccatgatcac ttgatccatc ccgtggttta gccgaatcgt
    20281 ctcagcaagc atttctcttt ttggcttcgt caaaccggag atttgtttta ataccgaagg
    20341 atcagcaatg attttttcga tagcatcttc tcccagcaat tctacaattt tttctgctgt
    20401 tttcttcccg attcctggga atttttcgct ggaaagatac gctacgatcc catttgcagt
    20461 tgttggcttt tcttgctcat atctttcgag tttaagctgc cttccgtatt taggatgatc
    20521 cactaattct ccataaaaac gataagtctc attttcttga atatcgccga aacttccggt
    20581 gactacaatc tctttttcac ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac
    20641 tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg
    20701 catttcttct ggctgcatcg gaagccgcct ccttcttcta tagtaaaggt tctggtgctg
    20761 tttcagttcc taaaaaatct gtttggttcc atactttcag ttcatatggc aataatctgc
    20821 aaggctcttc agtctctaaa atcgtcaaac tactattgaa caatccaccc atttcacgca
    20881 actcacttag ctcttttcct gtcatccatt gaatggctgc agttaaagaa gctccatgtc
    20941 ctacgaataa aagtgggcca tctttatgtc gggcaaccgc atctgctaca acagtttcga
    21001 tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg agaaggatca tacagatcta
    21061 aatgattacg caaattcggc agattatccg gatatttctg gtacatttca tcgatcgact
    21121 gaccttctaa agtacccagc cctagttctc ttagcttatc tgtataaaaa atctctaccg
    21181 gacgagcaag ctctttgttg ataccttctg ctgtatcacg tgctcgcttt gctgtactgg
    21241 aataaattgc tttaaaagga acatatttta cctttttccc aaatgctttg atttcttcgt
    21301 aactttgtgg caaaagcgga gaatcgccat tgctcccttg aaaacgtctt tcctgattcc
    21361 attgtgtctt cccatgtcgg gtaaaatata gttccatacg cagcaaactc ctgtctttct
    21421 tttattttac tctataataa actgtctaat ccagcttgtc attttcatag tgatgcgtca
    21481 attctaaatt agggaatcct tgctggcgaa gtgcttcata cactatcatt gcagctgtat
    21541 tcgataaatt caatgagcgg acatgctcat cattcatagg gatgcgtaaa cacttttctt
    21601 cgttttcacg cataaatgtt tctggcaaac cggttgtttc ttttccaaat aaaaagaagt
    21661 gctcttctcc atcagcaaaa ttttcgtcac tatatacttt atgggcaaat tttgagatca
    21721 aatgtagttt acgattacct aaaaatgtta aaaaagcttc taaattactg tggtaagtaa
    21781 tatttacatc attccaataa tccaaccctg cccgttttag atgtttgtca tcagttgaaa
    21841 aacctagtgg ctcgattaaa tgaagcggag tattcgtggc tgcacacgta cgggcaatat
    21901 ttccagtgtt tgcagggatt aatggttcaa ataaaacgat atgattcatc aggatcattc
    21961 ctctcatatt tatgttcgtt tctattttct gacaatttga tttttgcata aaaaaaaacg
    22021 tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt gaagctcttc tcactaactt
    22081 ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca acttgttgct aatataacac
    22141 cctcaacttt tttttgcaac ctctactcat taaaaactgc tagaaaaacg ttttctctta
    22201 gttcctttta ataattctat gtcaattgta atcttcttca aaggattctt atataagtct
    22261 gctttgattc gctcttctac ctgccattct aaaggtgaca tggccaaaag atctttttga
    22321 ttttcctctg gtatctcaaa ttcataggtt acacgctgac gttcagttaa tttcattgct
    22381 tcagcaaact tggctactac acgttcattg gaataactct gtttttcagg ttgattcgga
    22441 taaaaagcct gacgtagttc ctttaaataa ttttcttgtg gcaccacctt caacacttct
    22501 ccatcttctg agagtacacg ttggaattct tggtaatgag aaggcgaaaa gatatttaaa
    22561 accgcgttga atgtttgatc agcaaacggc aaattggtca aatcagctac acaccaaaat
    22621 gcttcggcag attgttctgt agctgcgtag actccttctt ttgaaatatc aaatccaaca
    22681 gcattttgaa tctttttcaa ttttgaaagt tcattcaaga agctaccttc tccgcagcca
    22741 acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga
    22801 tacatgccag attggatcat tctacgcctt ggaacgaaca ttccttgatc gtattctgtt
    22861 ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta
    22921 tttttgcata tcaagccatt atcagacttt tttacttctt cttggcaaac cggacagcgg
    22981 aacagctgat gattttctgc caaaaactgg cgtcctcggt caattttttt taacatagtt
    23041 ccccctcatt tctgttttat cttaccgtta gatgctcact ttggcaactg ctaaaaatat
    23101 gatacaatgc ctagaagaaa gtgaaagata aaggagaaga ttagatgatc aaagaatttt
    23161 gcgctgaaaa ctacacatct attcctctag caattgctag aggagccgat cggatcgaat
    23221 tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt
    23281 taagttatgc tggggaaaaa gatatccccg taatgacgat tattcgtcct agagggggcg
    23341 acttcgtcta taacgatatc gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga
    23401 aattagggac ggatggcgta gtatttggtt gtcttactcc ttcaggctgg ctagacgaag
    23461 aggccttaga actattgatc gaaacagcag aagggttgca gatcaccttc catatggctt
    23521 ttgacagtat tcctgaagat cggcaattcg aagcaatcga ttggctggta gaacatggtg
    23581 ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac tattgtagaa aatttcccac
    23641 ggcttaaaga attgattgcc tatacagatg gccgcttaat cattttgcct ggtggtggtg
    23701 tcactgcaga gaatgcagca catgtagcta aagaattgaa cgtaagcgaa gtacacggaa
    23761 ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa aaacatttgc aacaggcata
    23821 atgcttattg caaatgtttt tgttttttta cataaaatag cccataaata aagaagcaat
    23881 attgaaataa atcagtacac tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc
    23941 tactgctgga tcaaatccta gacgatccat tagcatcggg attaaactac ctgcaagatt
    24001 cgccactgtg attgcaaata gcatagccat ccctatgaca aaccccaaga taaaattatg
    24061 tttccaaaaa cctacgatta gaaaaatcgt gatccccgta acagctcctg tgacaacgcc
    24121 ggtcaagact tcagccaaaa caagtcgaac aaatccatga tctttctcat cagaaatcgc
    24181 aagtcgacga acagccacag ctagcgactg ggttccagca ttaccggcag ttcctgtaat
    24241 cagcgaaatg aagactgcta aaatactcgc ttcacttacc aagtcttcat agtgactgat
    24301 taaagaagcg gtcgacatac ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga
    24361 cgctgccttt actggatttt cattaatttc ttccacattg accccggcaa gtcctgaata
    24421 atcgctagca gcttcatcat caataacgtc gatgatatca tcgactgtga cgattcctaa
    24481 caaatgatca tcataatcgg taacaggaag agctaagaag tcataatctc taaatgtttg
    24541 tgccacatct tcttggtcgt cgcctacatg aactgaaagc actcgttcgc tcatcagatc
    24601 agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc agagaaataa cccctactag
    24661 ctgaccttct tgattaacga catagatgta atagattgtt tcagctacat ctgcttcgtt
    24721 cttcagcacg tacatcgcag agcgaacagt ttgattggct acgatcgaaa caaattcagt
    24781 tgtcatgatc gcgccagccg tttcatcctc gtaatggaga agttccttga tttcactggc
    24841 atcgtctgcc gacatcaaac ttaaatattt agcaatttgc tttttatcca gcgtattaag
    24901 caagtcaaca gcattatctg tatacatctc agaaagcata tcagctgcat agctaggacg
    24961 catttcatct aggtattctt tcatatgttc gttgtcttct tcaatcacat cgaacatatc
    25021 cgctaattct ttaggcgaca gataggaata gatcagctgc ctgttctctt ctgtaagaga
    25081 ttggtagaat tgcccctgct catagatatg catctctaaa aaactgtttc tgaatgcctg
    25141 aatattattt tcccttaaat cttgagtcaa ctgggcaaat ctttcctcta attcttgatt
    25201 ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc gtctcacaac tgcctccatg
    25261 tctgcggcta aaggctgctt gaactccagc aactcttctg taaatggatg gtaaaaacgc
    25321 agatcataac aatgaagggc ttgtcttttt attcccagat ccattcgccc gccatacata
    25381 tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt
    25441 cctgtatgca gctggatatc aactaacgcg atttctgtta gtcgcttctc tatccagtac
    25501 tcagtctgtg ccgaacgtcc ttcatcagag accattcgct tcaatagcga agaataatct
    25561 cgggcgatcg gcaaatcgat atgtccatgt gccgataaat ctgaaagcct tccactgact
    25621 aaggcctgat attttttcac aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc
    25681 gcaaatccat gctttgcaaa aagcatcaag ccagatgtat cccgatctag tcgcgtcacc
    25741 acatggatta cttggttttc gtaaccttgt tttttataat aagcctttac acgattagcc
    25801 attgtcccat ttggatggta ttgggcagga atagacgaaa cgcctgctgg tttatttact
    25861 accagaacgt gttcatcttc atacacgata tcgatcggtg tttcatccaa aagtacggtt
    25921 tcatgttctc cttcagcagg aatcacaatg gttaccttat catccttagc tagagaaaac
    25981 aagacatttt ctacttgatc attaactttg atttgaccgc cttgaaattt tattttcgct
    26041 aacagaccct ttgagatccc tttttctttt aaaaaatatt ttacttgctg agaatgatct
    26101 ttctcataat cccatgtaaa ctgcatatca atcctcacta ataaaggcat ctttcacacg
    26161 atgccaaaaa tgcatatgtc gataagaagc aaaatggatc cgttcttctg ctattcgata
    26221 ataaattgag cggatatttg cttttgcgac attcaattga tcaaccgtta caagataatc
    26281 ttctgtattt tccaatttta tttctagcca ttcatcatgg gcaatcacga tcggagaacc
    26341 caaagtacga aacactcgat tattcagtga agcaatctct gccaactgaa aggcattgat
    26401 actaggatgg atcacagcac cgccgacact tttattatat gctgtcgaac cagtaggcgt
    26461 agaaatcgtc aatccatctc ctctaaaact ttcaaacagc tcgtttttga tgtatacatc
    26521 ggctaccatc gtacgattgg cccgtttaat cgttgattca ttcagtgcta aaaaatgctg
    26581 gtccggtgtt tcatccaaat aactgatccg aacatccagc aagggataac taacactttg
    26641 ttcccggttc gttcgtaagc tgtctactag ttcttccagc tcgtaatccc gccaatccgt
    26701 gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc acatcattca gacaatgact
    26761 gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg actgagatga ccaattctgg
    26821 ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac
    26881 ttctatagtc tttgcttctt tattatgaac gatcgctact ttcatcccct gcctcctctc
    26941 tttcgctttc tttcttcaaa agcgttcgat agtagacatc atctgatttt cctcttccat
    27001 gggagaataa ccgctgtgct tcttggattt cttcacggat actggacatc tcttcatcca
    27061 actgataggc agcttctgcc gcacgctgaa gtcgttcact catttcttct ggaaaaacgc
    27121 cttgatattt ataattcagc gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc
    27181 gaatctggat ttccgccaaa attttcttct caccgctgat cagctgtaca ggatactcga
    27241 tcaccagatg ataagaacgg tagccacttg cttttttatt tgtgatgtaa tctcgttctt
    27301 ggagaacttt catgtctttt cttttacgga tgatctcaac aacttgatgg atatcttcta
    27361 caaactgaca catgatcctt aacccggcaa tatcagacat ttcttcttct aaacgtccca
    27421 ttggaatatg ccgtaattgt gattttgtta caatactatc gactggcttg actctcccag
    27481 tgacaaattc aatcgggaca tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca
    27541 gtttcacttt caattctgat acagtttgtt catatggtgc taaaaatgct tcccaatctc
    27601 gttccatagc tgatacctct acttcattaa cattcattgt ttattctacc atatatgcaa
    27661 agttttttcg tactcttgat ttatgcattg accaaaaaaa gaaaattagg caaaatagac
    27721 aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga atataaatct atgctgacaa
    27781 agcaagagta cgagatattc atcgctcact atcaattaac agataaagat ttccgtgtac
    27841 agactaatat ttatttcgat accgttgatg aacagctgaa gaaacaaaat tgtggcctac
    27901 ggatccgttt cgttggtcat caagctgaat atacattaaa aacacctgct gaaaaagggc
    27961 gtctcgaaac aacggatacc tttataacag aagaagcaga agcatttatc ttcgaaaaac
    28021 gtctgcctcg ttcaggcgca gtttttcaaa aactttctga tttgaatatc gatcctgctt
    28081 cattaatcca aaccggaaag cttacaacaa aacgagctga attccctatt gaagaaggac
    28141 ttttagctat tgatgaaagc tggggagaca atctacacga ttttgaactg gaactagagg
    28201 taggggatgc atctgtggga aaaattgctt ttataaattt tttaaaacgt ttttctttac
    28261 cttatcgtcc tgctaagaac aagatccaac gtatgcttga agctaaaaat tagaaacctt
    28321 tcattttcac aaggcacttg agttcatttt tttacttttt tctgttaagt tataggatgt
    28381 gaaagaatct agtcactagt tgtatagaat ctattttggg ggagattcat atgatcgaaa
    28441 tctatttatt tgttaatcct ttaggggaat actgtttcga aatggaacaa cagttattac
    28501 aatttatcga agaagagtac gggacaccat caaaagaaaa gatgcaattt cgctttcttc
    28561 ctttggtcaa tttgcagaca attggggatg tcatgcaaca aaaaggaatt tctcagaaca
    28621 atcttgagga acgtaatcac ttattctcaa tgacttattc tgcagcattg gactgcaaag
    28681 cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt gatcaaattg caagaagcag
    28741 tcggctgtaa tgacatacca tattctcaag aacttgctga atccatattt gaagaaatcg
    28801 gcggcgattt gaatatgttt aaagaagatc gtcagtctga cttcgttaaa gaagtattct
    28861 tttctgatca aaaaattgct cgggaaatgg gcatcacaaa acacccttct gcagtcgttt
    28921 acaattatgc ctgcgaccgt gattttggtg ttttagtaga agtaaaaggt acaagtagcc
    28981 tttggagaat cacagagctg tgtaaaacaa cagataactc atatcaagtt tttaatggtg
    29041 aacatttaca tacaaatgat tctcagttcc attcaagaac tagccattta cacttgcttt
    29101 ctaattaaaa
//
LOCUS       DAFEML010000030        28195 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFEML010000030
VERSION     DAFEML010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.030"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP468_001533"
     CDS             212..604
                     /locus_tag="LP468_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2081076.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP468_001534"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP468_001534"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL2081077.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LP468_001535"
     CDS             3165..4775
                     /locus_tag="LP468_001535"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL2081078.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LP468_001536"
     CDS             5067..5936
                     /locus_tag="LP468_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL2081079.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LP468_001537"
     CDS             6101..7372
                     /locus_tag="LP468_001537"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2081080.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LP468_001538"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LP468_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL2081081.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LP468_001539"
     CDS             8763..9026
                     /locus_tag="LP468_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL2081082.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LP468_001540"
     CDS             9471..9920
                     /locus_tag="LP468_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2081083.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LP468_001541"
     CDS             9977..11395
                     /locus_tag="LP468_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2081084.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LP468_001542"
     CDS             11395..12255
                     /locus_tag="LP468_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL2081085.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="LP468_001543"
     CDS             12429..13202
                     /locus_tag="LP468_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2081086.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="LP468_001544"
     CDS             13349..13714
                     /locus_tag="LP468_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL2081087.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="LP468_001545"
     CDS             complement(13862..15070)
                     /locus_tag="LP468_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081088.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="LP468_001546"
     CDS             complement(15089..15367)
                     /locus_tag="LP468_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081089.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="LP468_001547"
     CDS             15521..16216
                     /locus_tag="LP468_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2081090.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="LP468_001548"
     CDS             complement(16658..17455)
                     /locus_tag="LP468_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL2081091.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="LP468_001549"
     CDS             complement(17452..18636)
                     /locus_tag="LP468_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2081092.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="LP468_001550"
     CDS             complement(18661..19908)
                     /locus_tag="LP468_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2081093.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="LP468_001551"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="LP468_001551"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL2081094.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="LP468_001552"
     CDS             21888..22202
                     /locus_tag="LP468_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL2081095.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="LP468_001553"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="LP468_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL2081096.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="LP468_001554"
     CDS             22887..23531
                     /locus_tag="LP468_001554"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL2081097.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="LP468_001555"
     CDS             23546..23875
                     /locus_tag="LP468_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL2081098.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="LP468_001556"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="LP468_001556"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL2081099.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="LP468_001557"
     CDS             24863..25687
                     /locus_tag="LP468_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL2081100.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="LP468_001558"
     CDS             25680..26027
                     /locus_tag="LP468_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL2081101.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="LP468_001559"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="LP468_001559"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL2081102.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..>28195
                     /gene="dinB"
                     /locus_tag="LP468_001560"
     CDS             27077..>28195
                     /gene="dinB"
                     /locus_tag="LP468_001560"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL2081103.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
BASE COUNT         9223 a         4996 c         6032 g         7944 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaata
//
LOCUS       DAFEML010000031        27926 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFEML010000031
VERSION     DAFEML010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.031"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1034)
                     /locus_tag="LP468_001561"
     CDS             complement(<1..1034)
                     /locus_tag="LP468_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081104.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLV"
     gene            complement(1063..1380)
                     /locus_tag="LP468_001562"
     CDS             complement(1063..1380)
                     /locus_tag="LP468_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2081105.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(1406..1726)
                     /locus_tag="LP468_001563"
     CDS             complement(1406..1726)
                     /locus_tag="LP468_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081106.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(2190..3605)
                     /locus_tag="LP468_001564"
     CDS             complement(2190..3605)
                     /locus_tag="LP468_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2081107.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(3622..4938)
                     /locus_tag="LP468_001565"
     CDS             complement(3622..4938)
                     /locus_tag="LP468_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081108.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(5088..5786)
                     /locus_tag="LP468_001566"
     CDS             complement(5088..5786)
                     /locus_tag="LP468_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL2081109.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(6075..7031)
                     /locus_tag="LP468_001567"
     CDS             complement(6075..7031)
                     /locus_tag="LP468_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2081110.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(7144..7977)
                     /gene="msrA"
                     /locus_tag="LP468_001568"
     CDS             complement(7144..7977)
                     /gene="msrA"
                     /locus_tag="LP468_001568"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2081111.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(8152..9786)
                     /locus_tag="LP468_001569"
     CDS             complement(8152..9786)
                     /locus_tag="LP468_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081112.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(9773..11641)
                     /locus_tag="LP468_001570"
     CDS             complement(9773..11641)
                     /locus_tag="LP468_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081113.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            11607..13244
                     /locus_tag="LP468_001571"
     CDS             11607..13244
                     /locus_tag="LP468_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081114.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(13389..14129)
                     /gene="truA"
                     /locus_tag="LP468_001572"
     CDS             complement(13389..14129)
                     /gene="truA"
                     /locus_tag="LP468_001572"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2081115.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(14320..14955)
                     /locus_tag="LP468_001573"
     CDS             complement(14320..14955)
                     /locus_tag="LP468_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2081116.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(15102..16343)
                     /gene="sstT"
                     /locus_tag="LP468_001574"
     CDS             complement(15102..16343)
                     /gene="sstT"
                     /locus_tag="LP468_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBL2081117.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            16541..17539
                     /locus_tag="LP468_001575"
     CDS             16541..17539
                     /locus_tag="LP468_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081118.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            17552..19570
                     /locus_tag="LP468_001576"
     CDS             17552..19570
                     /locus_tag="LP468_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBL2081119.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(19630..20346)
                     /locus_tag="LP468_001577"
     CDS             complement(19630..20346)
                     /locus_tag="LP468_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL2081120.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(20573..21115)
                     /locus_tag="LP468_001578"
     CDS             complement(20573..21115)
                     /locus_tag="LP468_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL2081121.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(21120..21347)
                     /locus_tag="LP468_001579"
     CDS             complement(21120..21347)
                     /locus_tag="LP468_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2081122.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(21426..23306)
                     /locus_tag="LP468_001580"
     CDS             complement(21426..23306)
                     /locus_tag="LP468_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2081123.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(23495..24109)
                     /locus_tag="LP468_001581"
     CDS             complement(23495..24109)
                     /locus_tag="LP468_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081124.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            24251..24811
                     /locus_tag="LP468_001582"
     CDS             24251..24811
                     /locus_tag="LP468_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2081125.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(25116..25430)
                     /locus_tag="LP468_001583"
                     /pseudo
     CDS             complement(25116..25430)
                     /locus_tag="LP468_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(25684..27319)
                     /locus_tag="LP468_001584"
                     /pseudo
     CDS             complement(25684..27319)
                     /locus_tag="LP468_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         8789 a         5408 c         4373 g         9356 t
ORIGIN      
        1 actaagacca ttggtgtcaa aataaatgga atgaacatga tcgggttcaa cacgataggt
       61 aacccaaaca tcgttggttc attaatattg aagacacctg gcgcaatcga caagtttgtt
      121 acaaccatat atggtttgtt tttacgtcct actaaataaa tagctaacag taaacctaaa
      181 gttgcacctg ttcctcctaa gttgacaaag ctgtcaaaga aaggtttgtt cacgataaac
      241 ggtgcgctat gtccagctgc gattgcatta acgtttgctt caatggctgg cgcattgatt
      301 gtttgcatca aaggatcgac catattcgct ccgtgtaaac caaagaacca taagaatggt
      361 gtgataaatg caagcagtaa ggcagatgga taagagtttg caagtcccat aaatggttct
      421 tggaccactg tatagaaaga acctacgata tcatcaacac cgaatgcagc aaaaattgca
      481 gcaactaaag caaacgcaga gatagtgatc attgctggta gtaatgaagc aaatgctttt
      541 gcaactgccg gtggcacacc atcaggcatt ttgatgatca atttttcatt tccgcttaaa
      601 cgtacaaaga tttctgttga aataatccca acaataatag caataaacaa accgtttgag
      661 ctcataccta atgctccgcc taaagcgaag aaagagccta aagaaatcac acctgcggaa
      721 acaccgtctt ttcggtagcc gttagctaaa tgataagcaa gcaagaaagc aatcaagaca
      781 gaaagaatgg caaatgtacc gttccaagca gcagccccga atcctttcca tgattcacca
      841 ccaaaaattg agttcatcaa ttcttggaac ccgggaatcg gtaagttatt gatcattact
      901 gctaatgctc ctaagatcat taacggcata ctcaccataa atgagtcccg aatcgcaact
      961 aaatgccgtt gtgcaccaat ttttgatgct acaggtataa aatgtttctc cataaatgca
     1021 acaaatttat ccataaatct tccctctttt ctttactgta gattacgcgt tcaatcgacg
     1081 atacagatca atgatctctt ttgctaaatc tgtaaaagct atagatgtca tcagatgatc
     1141 ttgactgtgg accgtcaaaa gcgtgacttc aacgtgattt ccttgtgctt cttgtgtcag
     1201 catctctgtt tgagagtgat gtgcttggac taaagattcc tctgcatctt tgattttttc
     1261 atctgctaaa gtgaaatcac cttttttcgc agcagcaatc gcttccattg catcgctttt
     1321 tgcatttccg ccaaacatga tcagacccat gatggcttct agattttttt gatcttccat
     1381 ttattgtatc ctccgataat ttttattatt tgtttattag tttttctgct tggtcgagta
     1441 ctttttcacc attcatcatg ccatagtcag ccatattgat tacatctaaa ggaatgcctt
     1501 taggtgctag cttttcagca aattgatttt gcataaagcg tacttgcggt cctaaaagta
     1561 aaacgtctac atttttagat tctagttgat tatccgcatc tgaagcagat acagcaaaga
     1621 tgtctgcttc cattcctttt gcttctgctg ccttttgcat ttttgtgact aggagacttg
     1681 tactcattcc agctgaacat acaagcatga ttgttttctt ttccatttta aacacgttcc
     1741 tttctatact tacacttgta tataagcaag tagcgtgcca actttaaaag cgctttaaaa
     1801 agttgatatc atcacattta aggtctatac caagttgcat acacactaaa aaagaaagcg
     1861 cacactaaac acacaaatta atttttatta ccttttttct tttaacgtgc acaaaaaaag
     1921 ttgtgacaca aaacttgtca caactttttt caaataaacg gtattcaaaa gcttgcatct
     1981 gcggtaataa gtccaaccaa gttaaaaaca taagatgttg tttttacttt gctattctta
     2041 ttacttgatg caggacagct ttttcacaac ctctcaataa acggtgttca atcagctgac
     2101 cctgggtatt agctcaaaac gctggattca caacctcttt tatttcaaat aaccagtaaa
     2161 tacaatgaac atctacaaaa aacttctatt tatttataga tttcgtcagg caaatccaat
     2221 tctctcttat caatcaaagt ctgataccac gaagcagatt ttttcaatgt tctgcttcgt
     2281 tcatcgttca attcgattcg aactaatcca tatcgattct taaatgcatt cattggtgac
     2341 acacagtcag tgaatgccca taacatatag ccttcgcaat ttgcgccttc ttctgttgct
     2401 ttgatcaagt aatgcaaatg ctgtccgata aattcgatac ggtaatcatc ttgcacgatt
     2461 cctttctcat ccatatactg ttcttcatat tctcttccca taccgttttc tgttatcagc
     2521 caagggatat tatgataatt ttcttttaga tacatggcta tatcatacat gattttcgga
     2581 tagatttccc atcccctgga attattcatt ttcttcccag gtaaatcaaa gacttcataa
     2641 tatcgttcag gatggaaagg tgtctcttca ttccattgat aacgaggggc gcgaacgcgt
     2701 ttaggataat attgattgat tccaaggaaa tctactgtat gatgctgaat cgtttctaaa
     2761 tcctctgttg caggatcgaa ataaatcgat tgtttttgac acaactccag gaactcttct
     2821 gtgtagtatc cttttaccat cggatcaaaa aatactcgat tataaaacaa atcatacata
     2881 taagcagctt tttggtcttc tggagaattg gatcgagcat agaccatttc aggatttaaa
     2941 atacagccaa tccttccacc ataatttccg ctgcggtaaa tctctactgc tttagccgtt
     3001 gctaaaactt tatgataatt ccacatcatc cacttttttg tgttttgttc atgcggccag
     3061 cgaacagcat ccaaatagca acgcgtttgg ggaacgattg gttcgttgaa tgtaaaccag
     3121 ttttttaccc tatcaccgta acgatcaaag gcaatttgag catacttagc ataaaaatca
     3181 actacttttc ttgaagacca gccatcatat ttttccaaaa gaaaagctgg gacttcataa
     3241 tgttccaaac aaatcatcgg ttctacgtct gcttcgatca aagagtcgat catttcactt
     3301 atatgctgag catattcttc atctactata cagttctcat aatcagtaaa aaaacgagcc
     3361 caattgatag aagtccgata atgtgtcaga tggatggatt tcatcagatc cacatcctgc
     3421 tggtattgtt ccataaaatt agttgctacg gctgggccat acccattatg ccaaacaaaa
     3481 tgttcatttt tataccagct atctataaac gaatcctgtc cttctttttt tcctttccaa
     3541 ccttccgttt gccaagcaga agatgcagca ccaagaataa aattttttgg aatagtaatt
     3601 ttcatgattt cctcctgttt tttagatccc atcattttcc acacgatttg ctacttttac
     3661 aaatggcaga tagatcaaaa tagaaacaat aatacaaaca agttgcgtaa taactgcacc
     3721 gatatttcct gctgttgcca gataagcatt gacgatcggc ggcattggcc aagggaccat
     3781 tacaactgct ttcgccgcaa atcctaaagc ggttgcaaaa taaccaatcg ttccagtgat
     3841 aagaggcgtt aagataaacg gaatagctaa aattggattc agcatgatcg gcataccaaa
     3901 aataactggt tcattgatgt tgaagatccc aggagcaagg gataacttgg tgatttgttt
     3961 catatcttcc cgttttccaa ctaacaatac tgcaatcagt aaaccgatcg tgactccaga
     4021 cccgcccata ctcatataca tatcccaaaa tggcatagta ataatgttcg gtacttcttt
     4081 tccagcttca aaagcttccg tatttacagc aattgccgct aaaagcaacg gttcccgtat
     4141 cggcttcacc atttgatttc catggatacc aatcacccaa aagacttgcg caataaacat
     4201 caatagcaaa atacccggta acccttgtac gacaccttct aatgggcgtt gtacgacatt
     4261 gtaaatgata tcataaaggt acattcctgt aagttctttg atgataaatc ccgcagccgc
     4321 gatacccgat acagtcagaa tcgtcgggaa taaagcagaa aaactagcag aaacattcgt
     4381 tggcacggta tcaggcattc tcagctgtag tttcttctgt ttcctcaacc agcaataaag
     4441 ttcaatagaa aggatggaga ccaacattcc caaaaataac cctttcgtat ctgtatattg
     4501 tttagccaat acgttttcta ctataacagt ctgattttca ttcactaatt cataaacagt
     4561 tggattaaca gataaataag acatcactgc gatgatacca gggaatacac catccacttt
     4621 attcagcttg gctaattcga tccctatcag aaaaacagca tagatggtca agaaacttag
     4681 tgtgacatag ctgatggcag atgcgatagg ctttaattct tctaaaaaac gcaagaaact
     4741 tatctgtgct aagccatttt ccgagtcaaa gaccattgct gaaaacaatg tgccaaaagc
     4801 acccgtaata attaccggaa tcaatgcagc aaatgcgttt tttatcacca tgatatacct
     4861 taaattattg attctcgttg ccacgttccc taaaacattg gctaatttat ccataaaact
     4921 cattccagat cccctcattc ctgcttcttc tccttgacgt catctctttt tgtctattag
     4981 tcagcgctta catttcgatg aacagaaact atttactcct cttttttacc aaatataaaa
     5041 caaaaattca tctgatgtat ttatcataaa atacatcaga tgaactgtca attagtttct
     5101 ttttctccta ttattttctg taattctctc cgatttattg ccatatggac agtcattgca
     5161 tcaaacgcag caagtgcatt ccgcctttcg atggcctgaa cgatctctgt atgaatatcg
     5221 atcgtctcga ttttcagatg ctggatatca taatttttat taaacaaagc aattgattca
     5281 ttaatgattg ggataatatg cagcaaggct acgtttccgc tagcttctgc aatcatcgta
     5341 tgaaaatcga tgtctaattg aacatgttct tgtgtgcctt ctcgaaaaga agtttcaatc
     5401 ttttgcgtta attttttcat ttggacgatt tgattcttcg ttgcatattc cgctgccaaa
     5461 cctgccatct taggctccaa taaatatctc agttcaaata agtctcgtat catccgatcc
     5521 tgatcttcaa tcaaagaaaa accgagtggg tcattggcaa tccctcgctt atcactgaca
     5581 aatgtccccg ctccttgccg aacttcaagg atattcctgg aagctagagc ccgcacagct
     5641 tctcgcaccg tgcttcgccc cacctctaaa taatcggaca attcatattc attcggcagt
     5701 ttatctccta cttgcaactg catttccttt aaatatctaa ggatcttgtc agtagttact
     5761 tctactaggg ttttattttc ttccaaacca catacctcct tttcatctga tgtatttttt
     5821 cgtaattatt ataacacgtt tgaatcatct gatgattttt tgtatacaaa attgattaat
     5881 ccgttcatag acatacaaac gaagaagata tttaccataa aaaagactag gataaaattc
     5941 actcctagcc ttcgatcatt tttattttga acgacaaaaa atatgatgtt caataacaga
     6001 cgatcttcat tcgattcttg atgtcatctt ttgttttttt taatatatgg ataaaaagtt
     6061 tgattacatc gtttctattc tagaatttgg tcgattctca attcttcttc tggtgagaaa
     6121 tctaaattat ccatcattcg aacactttct tgtaactgac ttaaccgact tgctccgacc
     6181 agtacacttg taacagattt ttgtcgcaaa ttccatgcaa gggccatttg cgctaatgat
     6241 tgtcctcgtg atacggcgat tgtttgcagt gctttgattt tttccagagt tgatccaact
     6301 tgttcttctg aaaggaatgg tatttcctta cgatgtgctc tagaatcttc aggaatacca
     6361 tgtagataac gatttgtcag caacccttga gcaagcggac tgaacgtgat tgcccctagc
     6421 ccttcttctt ctaatactgg agatagatcg tcttctagta gtgcacgaga aaacatattg
     6481 tagcgcatct gatgaataat gaacggtgct tcctttcttt ttaaaatttc agtcattttt
     6541 tttgtatctt ctccattata gttggatata ccaatatata atgcttttcc ttgtcttaca
     6601 agttgcatca aagcttctgc tgtttcttcc aaaggtgtat cagggtctgg gcgatgatga
     6661 tagaagatgt caacataatc tagccccatt ctttggagac tttggtcaca acttgaaatg
     6721 atggatttac gagagcccca ttccccatat ggcccttccc acatatgata acctgctttg
     6781 ctagaaataa tcagttcatc acggtaggct tgaaaatctt ctctaaaaat acgcccaaag
     6841 tttttctctg cagctccagc agggcctcca taattattcg caaggtcgaa atgggtaatt
     6901 cccatgtcga atgcgcctct taaaatctct ctttgattat ggataggatc ataatcacca
     6961 aaattttgcc ataatccgag agataaaatc ggtaatttca aacctgaatg accggattta
     7021 cgatattcca ttttttcata acgtgcacta tctgcaatat acaatttttc tcctcctcat
     7081 caaatctttt taaaacgctt tcttttttct atttttagtt tactacattt taaagaaaag
     7141 gagttaatca aaatgatttt ttcgtatatt tttttgccat ttgtttttta ctcgttgata
     7201 gatcagaaat tgattacgtg cttgctggat ttttttataa cgtttcggtt gttttttgta
     7261 aaattgctga tgatagtttt ctgctggcca aaacgtaccg gctggttcga tttttgtgac
     7321 gattggttgg tggaaagttc ctgaactgtc tagtttctgt tttgattgtt ccgctaattc
     7381 tttttgtcgt tcgacttgat aaaaaatcac tggacgatat tgcttccctc tatcttgaaa
     7441 ttgtccaaat gtatctgtgg gatcagtaat ttgccaatag attgtcagca actcgctata
     7501 acttatttct cttgtgtcat aaatgatctc cacagcttcc acatgacctg tgtaaccacc
     7561 acttacttga tcataatttg gtttttcaac atgtccgccc gtgtatcctg acaaaacaga
     7621 taggatccct tttttcgatt caaacggctc gaccatacac cagaaacatc cccctgcaaa
     7681 tactgcacgt tcttgatagt cagcatcttg catggcatgc ttggaaaagt catatttttg
     7741 ctccttatca aatccttccg taatcaataa ataaaagtcc attacatcag gcgtcagatt
     7801 cattcggata gctaatggac gtagtgttgc ttctagtttt gataactgtt ctttaacgga
     7861 tatattttct cttatgtcat tctttgtctg aatcaatact tttcgttccc aatctcgtgt
     7921 attcggattc aaaatcagat tataaagtgt ttgaatgaat atttgttcct catccataga
     7981 ttctcctcct ttccgaagaa gacaagctag tgactttagc tgtaatttat cataaagtga
     8041 ggaaataagc gattacttca tccccctaca gatttttcgt ataaaaaaga gagaatcctt
     8101 atcgacagat tctccttttt aatcaattta ttttataaat gaaaagttaa tttacctttt
     8161 atggaaaact attttaaaaa ataaacataa atatgcagtt aatgtaacaa gataagaaat
     8221 aatagtcgtt actgtataac ttgtgcttac tttaatatca gcaactcctt tgactccgct
     8281 tatttgtacc aatccattag cattcacctg ctcctttaca ggttgatgat ttatttctac
     8341 attcgttcct aaataagcat atacaggaag tgtgattact tggctcttct cattagttac
     8401 tctatatatg atagaactac cagttgtttt ataaggaagg tttacccatt gactgccaat
     8461 ctttgcttcg tgttttatta tatgctcctt attctccaat gaagcgatag gagaataatc
     8521 atataaaaaa taatccattc ctttagtggt atacgcctct actgtttctt tgtttacaac
     8581 aatatgtccc ggctgagaaa ttattttttg attgaaattt tttttactag aaacagttaa
     8641 agtgattaat aacaaaacag tcataaataa ataaaatagt tctcttgtct tattgtatct
     8701 tctatttttg aaaaatatca tcgttaatat cagagaagag aatattattt gcaagcttaa
     8761 gatccgccaa ggaaattgta acaatttggc tggcgtattt tgcagaagat accatggcac
     8821 caaactagtt gtagctagcc aagtcaaaca cgtaccataa taaatctttt tttctatgtt
     8881 tgttaatttt ttaaataaaa tcaggggaat acataaagat aacagaccaa ctagtcccat
     8941 tgagtaagta gttaagtcgt tgttcatagc ttcagtcaga ctatcgaaca cattagatgc
     9001 atgagcatat aaatttgtca cgctaggttt gttgattttt tggtagagca tttgttcaaa
     9061 catcggatac caaaaagcac tcgtcagaac caatgtcatt cctgccgcac taaataattt
     9121 tttaaatata gcaataaaat ctgcattctt gaaaccttta gaaaccaaac gaataaaaat
     9181 aaaaatgata attaatgctg tactcattaa tgttgatagt acatggctgt acactagcaa
     9241 actcatactc aatgctagct ttacagacgg atacttttct tcttttccag agatgatttg
     9301 ataagcataa aataatacag ggataacaag tgttattgcg atagcttcgg caattgcgga
     9361 acgatagtag atgtctactg tccgataagc agagaaaata tagagacaac taaataaaaa
     9421 tgccgctttt ttttgtttta aaaaccgctc gccataatga taagctacga gtgttgtaca
     9481 caagttcaat aaccaaacgt aaataatata gcttacaatc aaattttttg tcatccaata
     9541 taacattaca gctggaaaaa aagtcagaaa gggataaaaa taatttacac catatccagt
     9601 ataattgaat gtctcataat taatcggact ggtaaaaata gtcgataacc ccttgattcg
     9661 agataagtga aaagaaagat ctccagtggt ataaatactc tgtgtatttt tgaaaaagat
     9721 gaaagaatat atactactaa ctataattaa tccactcaat attactactt ttttatttat
     9781 tttcattctt cttgtttatc tcctttttag tcacatatcg agaatctttc aacttattag
     9841 gtgcaaatcg tttaaaactt gaatacacca ctaaacaata agtcagaata ctgatccata
     9901 aagccatgag agcagttgga gtatattttg ttgtaatttc tatcttattt tctccagcat
     9961 ttacatccac attcactaag ccatgttttt tataagagtc atttacgact ttaccgttta
    10021 cttttacctg tgtacctaaa taagcatata ctggtactgt cactttttgc tttttgttgc
    10081 ttgccactgt gtaagtaatg ttattatctg cagctttata cttccctttt tcccacgatt
    10141 ctcctacttt tacttcatgt ttttctaagt gaggcctttc ttttatcgct tctgttgggg
    10201 cgtaatcgta taatcctccc atatctgatg ttgtataacg tgggagtgtt tcttcattga
    10261 taacaatatg accgtgtttt gattggataa cttttgcgta attttctttt gctgctatag
    10321 acgtgacgag tagaaacacc acagtagcgc caatgattaa ccatgaatat tttttattca
    10381 tagtcttttt cataaaaaca agcgttatga tcattgaaga aaaaaagatt tggataccta
    10441 agatacgcca aggaaactgg agtaagctta tcggtgtttt ttgaaacaaa aaccatggaa
    10501 ataaattagt tacgcatacc catgtagaaa ctacgccaac atagatgatt ttttcttttt
    10561 tctccatttc tttcagtatg aataaaggaa aaatcaacgc aaccaatcct aataacccca
    10621 tagtgtatgt tgtaatatcg ttatttaacg cttgaatgat actatctgaa atagaaagtg
    10681 cttctagctg caaatctgtt ttgaagggac tgtgtatttc ttgataattc atctgctgca
    10741 acataggata ccaaaaatag ctagttaatg cacaagtcaa aaaaacagcc tttactaaat
    10801 tcacgaccac aaattttata tcgtttttta tttgcttgct taaaaacaaa cgaactataa
    10861 tcatacaagc aatcaatgca ctacacaata gtgtagttaa gacatgagta tacacaagta
    10921 gacttatact gacagataaa gcgatgactt ttttttctct attgaatatc aatccataag
    10981 cataatataa aacagctggg ataatcgtaa gagcgattgc ttctgcaatt gcggatcgat
    11041 aatagatatc aactgttcga taagttgcaa aagtatataa acaactaaat aaaaaagcag
    11101 catctatctt tttaaaaaac ttttctccat aataaaaact aatcagaatc gtacaaatat
    11161 ttaataacca aatatataga acataactta atattaagtt atttgaaatt ccataaaaaa
    11221 cgactgcagg aattattgta agaaaaggat aaaaatagtt cagtccatct ccataattgt
    11281 taaatgttgt atagttgatt ggcccttcaa aaatagaaga taaccctttg attcgtgaaa
    11341 gatgaaaaga taaatcacct gttgtataaa tttcttgagc atttctcata aaatttactg
    11401 aatataaagt actaagtaag ataagaacta ctaaaagaaa tgctttttta cttattttca
    11461 tagatttgtt gttctccttt tttaattcta ttttcagtat actagaattg tcttttttta
    11521 ataagttttg cgttaaattt ttcatagcac tagtatgata tactagaaaa gaatcaattt
    11581 ttattacttt taaataggag aaaaaaatga aaaaaaacaa aaaccaaata atagatatca
    11641 tttttatgtt atttctaagt tttgcttacg tcatccctct attcatgtct aagggaatct
    11701 atcatagtgt caatcaggat acttactttc atttatctcg aatcatagga ctagataatg
    11761 tatggagttc tccagtaaac ttcaataact tcgatcatca tggaacaatg atgaatattt
    11821 tttatccatg gcttactctt tatccagctt ttttatttta taaaatgatg ggaaatcttg
    11881 ttttaagtta taatatctac tattttttta tcactttttt aacaatggtc gtttcttatt
    11941 tttctatgaa acaaataaaa aacaatcgtt atatttcgct gttattttcg attatttata
    12001 cattttccgc ctatcgtgcc attgacatat tccatcgtgc ttcattggga gaagctgtcg
    12061 ctttaacatt tttgcctttg atactaatgg ggtgttacga aatttatatt agagattacc
    12121 aaaaatggta ctggttgtct attggcatga cgctagtagt gtatactcat ttactttctg
    12181 tcgctatggt ttctgtattt attggaggaa cgttgtttct ttctttttat ttttgggacc
    12241 aaaaaatcgc tagactctta agtcttttaa aagctaccgt cctcaccttt tttttaagtg
    12301 cgggattctt aattcctttt attcaacaat ctagagcaca agaattgaaa gtcccactgg
    12361 gaaaagaatt aagtggtatg gctcctagtg atatgctgac acatatttta aataataact
    12421 ataacaacta tactattgga ttattcttat ttctcggatt gattggtgct tttattttta
    12481 taaaaaaatt aactgctgat gatttattta ttttctttct tggtgtattt gttctttttt
    12541 gttcaaccaa tttatttcct tggcaacttt ttaaccatac accagttaag agtctacaat
    12601 ttgtctggcg gttaaatggt ttttcttctt tatttatagc ctatacgatg agtatagtga
    12661 tctattatat tttttctact aaaaataatt catggaaaat aatggtcttt acgtttcttg
    12721 cactaatatt gcatctctca ggagtaagca attctatcca tgctaacaaa gattcattaa
    12781 cacttatagc acctgaagac gctgttgcta tagctgaaaa ttacaatcat actgattatg
    12841 caaacaaaga gtcaatctat catcctgata tgattaataa tgatcaatat ttactaggta
    12901 accaggaaat aaatccaaca actcatttta tgagtaacaa acttacaatt gaattagata
    12961 attcgaataa taaaaatact gtcttgacga cacctattta tcgttataaa gggcaagtgg
    13021 cttctattaa tggcaaacta gtacaaacaa aattatctaa gtttggcaca actgaattaa
    13081 ctattcctcc aggtataaat aaagtcgtta ttacttatca gtacacaaaa ctagcaattg
    13141 cttcaagata tttatctatc gttactttga ttttattttt actttatcga tttacttttt
    13201 ctaaacaaaa acaaccgaga agagaagtac aacattctca ctagattttt atttaagaaa
    13261 gactttttag ctgtacacat aaacaggcta aaaagtcttt ttttatattt ctttaatttg
    13321 cttcatacat tatttaacat cgatatttat actgtgaaac atgcgtttca tccattatca
    13381 aagtattttt atcgataata aacttcatcc aaaaacagac cttgtgcagg gacggtttct
    13441 cctgcatgtt gccgcacttt gctttcaaat atttcatcga ttgtttctat cggcatggca
    13501 cctgtgccga tttctagtaa tgtccccatg ataatccgca ccattttata taagaatccg
    13561 tctccgacaa aagtaaaatg aagcatttct ccctttcgtt cgatagataa ttcatcaatc
    13621 gtacgcactg tggatttttt tgattttttc aatgcagaaa aaccaatgaa atcatgtgta
    13681 cccactaatt tttcgcaagc tgcattcagc ttgtccatat ccaactcttg agggaaataa
    13741 aagctgtggt ttcgctcaaa tgctgaagga atcacgttgt tccaaacata atagctgtat
    13801 tttttgccca ccgcattata tcttgaatgg aagcgctcag gcatttcttc gattcttttg
    13861 atgacaatat cccgcggaag gtaacgattc ataaagtcga tcatttctgc cagtccaatt
    13921 tctgtgtttg ttttaaaatt tgctacttgt cctcgcgcat gggtgccagc atctgttctt
    13981 cctgatccaa taatttctat ctcttcattt gtcatctgat gcaatacttt ttcgattttt
    14041 ccttgaatgg ttttatcgtc atctccaagt ctttgccatc ctgaatatct ttttccgtca
    14101 tattcgattg tcaacttgat gtttctcata ttttagtggc tcctctgtct tccatttggt
    14161 cttctctcta cctttttaag attgtagcac aaaatatagc tccttgcttc tctaagacag
    14221 aagctataca agaaaactgt ggaaatatat atttcagaaa aacaaaaaac agccaccgga
    14281 tgaagtatcc gctgactgtt caatttgacg gctcaagttt tactgtttga gatgcaagat
    14341 actcaaccag gcaatgggca cataattaaa gaaaaaactg attctttggc aaaaacctat
    14401 tttattcagt aatggccaag aatttataga aggaattctt gccagtccat aaatcgccgc
    14461 aaaaagcaaa ctgatcacag acagtccaag gtataagtgg cttacgtcca tttgcccatt
    14521 ttttcgatag atcaagaaaa gaagaactgg aaacaataaa aaaccactgt aacctaaacc
    14581 tgatccgata ttatggaccc atgtcgagac attccacgaa gattcatggg tattgatact
    14641 gaacaaacct gtaaagatac aatcacctat accatagaac gcgatggctg ctgtaactag
    14701 ggtagctaac acacgagatg tactaacaaa tgcagcatac aatgcaggca atgacaggat
    14761 gaaaaagatc cctgaaacca cagaccaaat aagaaacgct tttcttacag gactggaaac
    14821 ctctccaaat acactgatca cgctcttcat ttgatctaat tcaggataat acaatcctaa
    14881 tacgtacgga gtcaaaaaat cactcagcac gcctaataat aaaaagaaaa aaccaaattt
    14941 acgtaaaaaa tccatgatac gcctccaata acaattacct atgcttttaa ttgttattat
    15001 aaacgacttt atcttgattt aacagaaacc tctatttaca cgaacatcta tataactcat
    15061 taaaaactcg aatcatttta aaaatactaa atatctaacg ttcaacgttc acttaatcca
    15121 tctaaacaat ctttcaattt gattttttcc ccacttcttt tacgcgcgcc tagctctcct
    15181 attgcagtaa acaacagatc acttgacgaa tttaaggcag tttccattga atcctggata
    15241 acaccgataa taaatccaat accgacgatt tgcatcgcga catcattaga gataccaaac
    15301 aaactacatg ctaatggaat caataacagt gaaccgcccg caacacctga agctccacaa
    15361 gcagctaaag cagacaaaat acataaaagg actttcaaaa caaaaggtgc ttcaatccct
    15421 aaagaatgta cagcagtcaa cgtcatcaag gaaatggtaa tcgcggcacc gcccatattg
    15481 atcgtagcac ctaacgggat cgatatggaa taagactctt ttgtcaattt caatctttca
    15541 gccaacatca tgtttatcgg gatatttgcg gcagaacttc gggtaaagaa agcgggaagt
    15601 gcgctttctt tcaaacaaaa gaaaatcaat ggatagggat tttctttaat aaacaaaaac
    15661 gtgaggaatg ggtacacaac taatgcgaca aacagcatcg taccgatcaa aacaagtaaa
    15721 agctgcagat actctgccaa tccagcgatt ccagtcgtag caattgattg ataaaccaat
    15781 cctaaaatcc ctatcggagc aaatgcaata atcacttgta cgacttgtga caacgctata
    15841 gatatctgat ccaccaactc ttttgtcgat tctgaacgtg ctcgaaaagc tagtcccaac
    15901 aatacagccc agaataagac gccaaggtaa ttcgcatcaa taagagattg aacaggattt
    15961 tgtgtgacat tcgtcaacat agtagataaa acactttcca aactttgcgg tgctttttca
    16021 gatactgttt cttgtaaagt aataggaaca gtaaaaattg aacttacaat aactgctaca
    16081 agtgcagaaa gcaatgttcc cactaaatat aagatcaaaa taggcttcac gaatgtctta
    16141 ttcccaattt tatgcttggc aattgacgcc atcgtcaaga aaaaaaccag aataggtgcg
    16201 attgccttca agcaactgac aaacaacgtt cccaatattg aaataaatgt ccatgtgggg
    16261 aaaaagatac caaacaatat tccgactaaa ataccaacaa caatacgttg aactaacgac
    16321 atatccaaaa acttctctaa caaatgacca ccctttcaca attttaacaa tcattgtatc
    16381 attttatgca aagaaactaa aggtataatt ttctaaaaat tctaacaata caaacaacca
    16441 tttcttgcta attttgtact ttttctgtct acacgttgtt ttttgagata ttctaagtta
    16501 ggatgttatt aatgggcaac ttatcaggaa acgttttctt atgtttttgt ccaatttttt
    16561 tgtgaggtgt ttattcttga aaaaaataaa gaaggagagt tatggcttcc tgacaatctt
    16621 tgtcgcttgt ataatgatgg ttttacagcg tatattgatt tcagcagtca ctattcctac
    16681 atatgcaaca aaccctggtc gattctacat ctatacattt ttacaaactt ccgttgttat
    16741 tggtgcaaat ttgatcccac tttacatggg ttaccaatat caaaaaatcg cccgtttaaa
    16801 agttttacat tatttaagtc gttttgcctt tatattccta atagccacac tagtttgcaa
    16861 tatctttttt tacgtacaag ctggcagctt gaatattcgt gattattggc ttatcctaac
    16921 acctatcagt cagaattact ttacttatgc tgtttcttgt actttgcttt tttgtagtat
    16981 tccttataca gttggatttt taaataaatt atcgaaaaca acaattaaat atctactatt
    17041 atttttaaca attggattag ttggctgctc tactctattt aataaagacc cgtttgcatt
    17101 acagaatgga cagagtattt tatggatttt ttatttattt ttaatgggtt atggtttgaa
    17161 agaatggaac tggaaagaaa aggtccgcta taagcttcct caagtattta tcagcttgat
    17221 tgttttattc ggtttgatta ttttgatgac acaaatttca ctcatcatca gaggaaatac
    17281 agatacagcg ctgaggtttt ctaaaccata ttctctcttc gcaatgtatt atactttctc
    17341 ttcgttttta tttttagaaa tgctatctga taaattaggt ataaaaggaa gaggaaattt
    17401 tcttgctgta tttttgattg tcactcaagt tatatgtaat ttccctttag tttcttatcg
    17461 cgtatctaca tttatgaaac gtgaatttcc aaactcaggg aaggcatggc tgataaatat
    17521 cgggcagttt tttatttgat atttattagc agtgtccctc ctagttatct ttttatttta
    17581 tatacaaaaa atccgtttca ttcatcgttt catcgaatac ttcgcttttg attcgattga
    17641 acaattaact cagcgttgga aaaaaagaat tcattggctt tttgttcata aaagttattt
    17701 tttagttgca gcattttttt actgctttac cttcgtgcag attttcgttt tagaaccaaa
    17761 agaaggttgg aaagaaacta tccaggttgc cttaaaaata tttactcagc gacaagcacc
    17821 catgatcctg acaatcatca ttattatggg atttttcttc ttactattgt tgatttccaa
    17881 tcgtttttgg tacgccttga ctgctacctt gatcattaac ttactgctca ctatttcgac
    17941 agtaatcaaa atggaaatgc gggaagagcc tgtctttcct tcagatttaa aaatgctgac
    18001 cggattgtca gaactattat cgatggttag cccagtctta ttaatcgtgg gcggattgat
    18061 ccttctccta ttattgatta ctagtattat tgtacaacgt agactacaaa aacagtattc
    18121 cttgaagatt cattggaaac gtcgatttat cagtatcgct gtattattag gatgtttttc
    18181 gggtgtcttt ttcattaatc acaaaaattc gccttctttc ttgctgttta atttatttaa
    18241 agtaaacaag actttcttta accagcaagg cgccgtaaaa gataacggac cagtcattca
    18301 attcctaaac aatatcgaca ttaaaatcat ggaagaacct gctggctatt cgaaagaaaa
    18361 aattaatgga ataatgaaaa agtacaacac aaaggcagat gaaatcaacc aaacaagaag
    18421 tgactggtta aacaatcaga cgatcgttct caatttaagt gaaagcttca gtgatcctgc
    18481 acgtgtccct aatctgacag tacctacaga ccctattcct tacatcaaaa gcattataac
    18541 agaaggaaca ggaggattga tgttatccgt cggttatggt ggcggaacag ctaacatgga
    18601 atgggaagga ctgacaggct tgagtatcag taacctgtct gcttcgttag ttacacctta
    18661 tacccagcta gtggagcgtc agaaaataag tccaaatatt accgatctat tcgatgaaaa
    18721 aatagccatc catcctttta cagctgctct ttatcgcaga aaacaagtgt ttgataaatt
    18781 tggttttgac aggttctatt atttagacag tccggataaa ttaacttata cggataaaat
    18841 agaacaaagc ccacgcatat cggatgattc agcatacaaa gaaaccttga aagctttaca
    18901 aagcaatacg gaaacgtcac aattcatcca attatccact atgcaaaacc atatgcctta
    18961 tgatgattac tatagtgaat tgaactacac tgctgaagga actgctgtca ttcctaatag
    19021 aagaaaagaa ttacaaactt atatgcaagg ccttcactat accgatacag cagtaaaaaa
    19081 attcatccaa gaaatcgaca aaatcgataa accgattacc tttgtttttt atggtgacca
    19141 tttacccgca atctatagtg ggaatgattc gaaaaaatat ggattagaac agcaccagac
    19201 agattatttc atttataaca acaagtatag tcgtgaacaa gcagctacgt taaataaaga
    19261 agttgttgct cctaataact ttggtgctat ggctcttgag catgcgaata tcaaagtaac
    19321 tccttactat gcgttgttga cagaagtatc taatcatcta cctgcattaa caattgatcc
    19381 tacagaaagc ttgtctaatc gttttaatgg aaaacaggtc tttgttacag aggatagtca
    19441 aattatccaa gaaaaaaatt taactgagaa acaaaaagaa attctagaag attatcgtct
    19501 gatacaatat gatcttgttg caggtaacca gtacagtgca acatgggcga cacaaaaaat
    19561 aaaagactaa caaataaact gagcaagggg ttgtgataaa agacatgtca caaccccttg
    19621 tttatctcat taatttgctt gtccataaac gatttgatta aagccatttt tcaattcatt
    19681 attcgctgtc tcgttgaagt aaagataatt atcgggattc ccctgatttt gttgtgtcac
    19741 caatactttt ggctgatttt gctgaaaccc gaatagatag acgtgctttt tcagatatgg
    19801 ttctgtctct gcatcggaat agacggctgt gatttgatag tctgcttgac ctgtcccact
    19861 ttctgaccat tctgcagaaa caggcactcc accaatagcc atcttccact ccccgttcaa
    19921 aatagcttga gggactttaa gaccatataa gtccacactc atttgattcg tataactttt
    19981 gtattgttgt cccattgttt ggccccattt ggtcataaat gcctctaatt gtgcggattt
    20041 gtctgcattc cacagtgttt gttcaacttg ttcgctgctt tctgaagagg aagatgaagc
    20101 ctctacagaa gaacttgaag tagatgtttg agttgtttca gtcgttttgg aagactctga
    20161 cgaagtagag gtatctgctg tttctgtact tgctgcagtt gacttgctct ctgtgctagt
    20221 tgttgtagta gttgcaactg ttgctttcgc tgtttctttt gttgattctt ttttcgattc
    20281 attcccgttg gtacaaccag ctaacaaaaa agctagacca attgttacta aaatcctttt
    20341 tttcaattaa aaaactcctt tcgattactc ccacttcttt attctatcaa ataagcaatg
    20401 tgattttatt gatttttcgt attttctcat caatctttca aatcttctaa aaactgagaa
    20461 gcacccgctg atgttgtctg taatacatca gcgggtgctt cttttatttt aatcttcgtg
    20521 attttccaat ttacctcacg ctttatattt gtatttgaag aaacatagac ttttagtcat
    20581 catcgtcttc ctcatccaaa tcttgtcgga cagtttttcc ttggagtctt tgtacttggt
    20641 agatgatttc tttattgaaa cttaaaagtt caacaagcaa ttgttgcaag ccatattttt
    20701 cttctttttc agctaatttg attgcccgtg tgataaagac attttggaaa tcaaaatctt
    20761 ttgcaaagtt ttccaacatt gttgaggctg gtaaatattt gttttgacca tgttcgtaaa
    20821 tttttccata acgcatgact tcttctaaag tagacggaac gatttcattt tcaatcacta
    20881 actcatgaga gattttattg aaccatctcg cttcttgatc agcatattct gaaaaaaggg
    20941 tacttaattc ttgcgaagat gtacccaaaa catacaattg tgcttggatc aatttcattt
    21001 cttctaattt aaaatttgct aatacatgcc ccaccatggc gccagcagtt ggtttatgat
    21061 ggtcgatatc tgcttgtttt gtttcttgaa caaatttttc ttccactata ttcattgatt
    21121 tacgcctctt ttacttttgc tgattggact tcataaccta atttttccac aactgcagct
    21181 aattgttcag ggtggacttc atctggatca aagtttgctt tgattttgct cgcattaaac
    21241 aaaactttcg tattgcttac cccaggctgt tgagaaaccg catgttcgat tttttgcata
    21301 cagcttggac aagctagtgt atctaattgc ataataattt ttttcatcgt agttcttcct
    21361 tcctttttct tgatagtctt attctagatt acagcttcca taaaaaaatt gattcttatc
    21421 aagttttacg atttttcttc tttgctttcg tgtccaaaat acaataaacg catcgcgtta
    21481 aagataacga tcaagatact agcttcgtga acgaacatcc cactagccat gtaaataaac
    21541 ccggcaaata agccgttgag taaaaataag acgacaccaa tggcaatcac tacattttca
    21601 cgggtattta aaacagtttt cttagccaag cggtaggcat gaaccaacga ttcaaaatta
    21661 gattgcatca agacaacgtc actcgtttcg atagcaacat ccgttcctga tcccatagca
    21721 atcccgatat cagccgcagc caaagaggga gaatcattga ttccatctcc aataaaagca
    21781 acgcgcaatc cttgttcttg gtattttttc acaaattgaa ccttttcgtc tggtaataat
    21841 tcagcatgga cttcatcaat gcctaacata tcagctacat aatcagcagt catctgatta
    21901 tcacctgtca gcatcactaa ctgttttgct cctgcttgtt tcaacttagc taattgttca
    21961 gcgacttctg gtcgaatcac atctgacaca cctatgattt gagtgatttt tttgtcgatt
    22021 gctacaataa tgaccgagct gcctgtttgt tgtaattgat gtaaatcttg tacttgcttt
    22081 ggtgtgagag aaagtttgtg agcggcaatc aatttggtgt tgcccgcaca aactgtatga
    22141 ccatcaatct cagctgtgat tccttgtccc ttgattgtct gattatcttt gactgctaat
    22201 tgttgaaaat caatgtcttt ctcctgagca taatggatca cggcgcgccc cagaggatga
    22261 tcggataacg tttctaatcg agccactaaa gctaagctgt ccccttcatc ctctgtatag
    22321 ttcttgatag tggatacagc agtagttcct ttggtcaatg taccagtttt atcaaagaca
    22381 aaagtatcga ttttggaaaa agtatccatt gcttcaccgc ctttgactaa gatgccccgt
    22441 ttcgctccat taccgattcc tgctacattc gaaacaggcg caccaatgac taaagcgcca
    22501 ggacaaccaa gaaccaaaac agtgattgct aaacgaaaat cacgactaat cagaccaaca
    22561 accaacgcaa taagtaaaac ggttggagta taatactgag aaaatcgatc aatgaatttt
    22621 tccgcatggg atttggtatc ttgtgcttct tctactaatt cgataatttt ggcaaaggtc
    22681 gtatcatctc cgaccttagt tgcttcaatc gtcacgtagc catctgctaa aatcgttcca
    22741 gagaagactt catctccact gattttgacg acttgtcgtg attcaccagt cactgcggct
    22801 tcatccgcat accctttccc gtcaatgact cgtccgtcca caggaatagc tccaccagtt
    22861 tttactaaga cgatatcgcc ttcttccacg tcatcgattt ccacttcttc agtcgttcca
    22921 tcttcttgga caacactagc agtagatggg gccatctcgg tcaaagcctt gattgactcc
    22981 cgcgttttgg tcaatgtttt ttgttccaga tagctaccaa acaaaaacaa gaatgtaacg
    23041 atagctgact ccttgtattc tccgatcata aaggcaccaa gcacagcaat agtaacgagt
    23101 aaatcaattg agataacttt gactttcact gcctgatacg catggatcat aataggtatg
    23161 accgcaataa tagaagctat ggctagagca atgttataga acaagacaaa accagtaaat
    23221 tttccgataa aaccaaaaat aatcaacaca gctgataagg cggtgatatg atttcgatgc
    23281 tcttggatcc acttttgtaa tttcatcttt ctccctcttt tcctttcatt cttacgagac
    23341 taagtataga tacttatcca tcataaaaaa ttgaccacta tcaagtttag tcaaaaaggc
    23401 ggttttcttt tggtagaata cactacaaaa aatagttagc aagaagactc actaaaagtg
    23461 atcttgccaa ctattgtcgt ttctatcgaa attttcattg aatgattttc ctgtacagca
    23521 tacatcggag atctatttct ttatctaaga tttttatctt gctaattttt tcctttagtc
    23581 tttcaaatcc acgtcgttca tagaattgat acgtacagcc actatctgta aaaaggaata
    23641 tttcttttcc tttctctctt ttttcaaatt ctgttagcaa cttggtaccg atgccttttg
    23701 ttttcaaatc aggatttgca gctaaaaaaa tgatctctcc atctggcgaa tgcttcttta
    23761 aatatgctgc aagcatttgt tcatttgctg tctcgtaagc tcctttactt tctttagcaa
    23821 atatattttg taaaaaatcg aatatcttaa catatatttg ctgtccaaaa gaacgatgtt
    23881 tctttttttc tccttttatc tccgccagca aaacacctgc caactcgtcc tctgcataca
    23941 aagcaagaat ttgagttgct cgattcaact ccatatacaa aaaatatctt ccgtaaagat
    24001 tcagcagaag ttcattttcc atatatctct caaagttcat tccttcaaca gcaaaataga
    24061 tagctttttt gtaatctttc ttttctaagg gtttaaaagt tagtttcatc atttcgcctc
    24121 ctcaacttca atgattgtgt tatacttaca ttataataga cacagtgtct actatctata
    24181 atcaatcatc tataagtttg tcgattaagc gacagctttg ctttgatatg tcggataagg
    24241 agataggtaa atgaaaaaga cagatagacg cgtcaaaaaa acagaaaaag ctttggctga
    24301 aacactatcc acattattag taaataaaaa gattcaagca atcactatac gcgaactaac
    24361 agaaacggca gatgtacatc gttcgacttt ttatacacat tataaggata tctatgatct
    24421 atatgatcaa ttagaaagca acttttttcg ggatctaaat gaaattctct cttatgatcc
    24481 agcccatagc tatgaggaac tatacactcg cttgattgac tatgtttacg caaatacttt
    24541 tttatatcgc ttatttatcc tcaaccatgg tgatatttcg tttcagaaga aagttaaaca
    24601 agttattgaa gaaaactatc tgaacatatg gctatatgaa gacaagaaaa cgattatcac
    24661 agaagaaatg agattcttta ctacgtacca cgtccaaggt tgtctatccg ttctcaatcg
    24721 gtgggtagaa agcaattaca agtactccaa aaaagaatta ttagaactct tacagaaact
    24781 gaatgatcac atagagaaaa tcatgccttg aataaaaaca tactaagctt agttaagaag
    24841 aaccgtaacc ttctcgtata acaactgaat cttatttagc caaattgttt actgaagatt
    24901 ttttgagtaa aatttctata attcctactt attgaaaagt agtttgtagt gctgcttctc
    24961 cctctctaag tgatatatct tgttgtacca atcaaattca cctcatcatt aataaattac
    25021 ttttaggcta atttattaca acttataggt tgaagctgta accaatttat agtcatatta
    25081 tatttttatc atccagttta ttgaattctt ctcgtttacc tcaattcatt ttcaagggga
    25141 atcagctcat catctaacat tttacgccat gctcgcttca tttcttgtgg gtatttaaat
    25201 ggtttcgctt ctggatgttt ggctttatat ccttcgtaat ccttactgtt gataattgct
    25261 ttcatattag gaattggatc ttcacctggc atatattgca gattagaagc atgtaatttt
    25321 ttctcagaaa caaaccactc attggaaaag acatgaatca aatcatcact tacttgtgta
    25381 aaatagcgac gtttaatgac aaagatatct tcattgctat ctagtgtacc ttcatttctt
    25441 tgtgcttaaa ttcaaagata attttctcaa taaagatttt tgattccagt aagattcctt
    25501 tactcctttt acaacatagc gttgtccttt gttttgaaac atcttcttcc cctctttgcc
    25561 attaaaaata gcccaattct ctataaagaa gattaagctt cattattata atataaagtt
    25621 taaatttggt ttattactta ctttttctta ttctctagta agctaatatt gaaaaaaatg
    25681 taatcagatc attattttta tatgttgtaa cttcctgata agaaaactaa ttaaaagaaa
    25741 gaggtaacta cataaactaa ttaaaaaagc taacttcata gttggaggat aaatggaaga
    25801 aacttcaatg attgtttctc cttgtgttcc ttcaatcgac actagtccta ttatcaatct
    25861 ctcttttttg tccatttact tttgcgactg ttccccaata atcaaataca ggaagcgtta
    25921 ttttttgtcc tttagattca tgtactgtat agactatttt cgaatccatc acttgataag
    25981 gcatagtatg ccattccttg ccaattctta cttcatgatt ctgcaaatgt tctttgtatt
    26041 gtaatgcttc cgtgggtgca tagtcataaa gtcctccggg aaggagtgtc gtgtaacgaa
    26101 taagattttc ttgattcatt accaagtgat ctctctgagt gacaacttta tgttcatagt
    26161 ttgcttttgt tgcagcagat acagccaaca gtaataaaac aattgccgtt atattaacta
    26221 cttttctttg cttagctgat gtgctcttca tgaaaacgaa cgataaaatc aacgagccaa
    26281 acagtacttg aaagcctaag attcgccaag gaaattgaat catttgaatg ggtgtatttt
    26341 gtaataaaga ccatggaaaa aatttggtgg ataagagcca agagactacc gcactaaggt
    26401 aaatcacttt ttctttgcga ttaaatcctt taaaaaagaa gagtggacag atcaaagaaa
    26461 taataccaat gattcctacc gtaaaggttg tcaggtcatt attcatcgca ccaatcaaac
    26521 tatccgagac atttaatgct tggtgttgta aggtcgtttt atctggctca ttaatcgatt
    26581 gaaccatgat ttgtcggaac atcggatacc aaaagtatgc tgttaaaaga atcgtcattc
    26641 ctactgcctt tgacaactcc acaatcaacc ggatgctttc tttttttctt gtttcactta
    26701 ctacaaagcc gcctaagact agtaagccaa cggctattac actcataaaa gtggaaagaa
    26761 catgtgtata aatgagtaag ctcatactga ctgctaatgg aattgcacat ggctttttct
    26821 cataaatcag tgcgtaagca taatacataa ctatcggtat aaccgtaagt gcaatcgctt
    26881 cagcaatagc agaacgatga taaatatcaa tcgtacggta cccataaaat gtatataaac
    26941 agctaaatat aaaagccgca tcgattcttt ttaaaaattt tagtccataa tgaaacatca
    27001 gcatgatagt acaaacattc aatagccaaa catataagat ataactaacg attaaattat
    27061 tacttatcca ataaaaaatg actgccggaa aaaaggtcaa gtagggataa aaataattca
    27121 ctccgctccc ataatgatta aacgtcgtaa aattgattgg accagaaaaa attgaagata
    27181 accctttgac tctagcaaaa tggaaggcaa tatcccccga tgtagaaata gtatgaacat
    27241 ttctaaaata attgattgaa taaagtccag caataattgc taggagaatg gacaatatta
    27301 tttttttctt tacttgcatt acttaattat atactccttt catggattgc tttatctagt
    27361 ataacttaaa ttttaaataa atcgttattt atttttactc tcacttaaaa aagcactaaa
    27421 attataagag agggaggtaa tggtctgaac accaagaatt gttccaacat cgaattgctt
    27481 aactaatgag ttcaaagctt aattatgtgg ctcttatatt taccgagcgt ggattgcgat
    27541 ctctttagcg aaacaaacat ctttcataaa aaaaacagcc atatccgctt tcttggatat
    27601 gactatttac tactacttta ctatctttca ttcttcttgt ctcacttatg ataaggcgct
    27661 gcgtatcatg agtgaatgat attaggaaaa cttcataaaa taaatctttt atacatttcc
    27721 acttctagat ggtcattcat gttagaagaa tcaaactatt tttttactgt cgtaataata
    27781 ttaaaacact agaacaaatc aattaaattc cataaaatat aaataataga cctagcatca
    27841 tctggtataa aatggatgct aggtccgtta tatttactca aaattgattc tacgaataga
    27901 tcttcttatc atttctattt tagtag
//
LOCUS       DAFEML010000032        26166 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFEML010000032
VERSION     DAFEML010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.032"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..626)
                     /locus_tag="LP468_001585"
     CDS             complement(<1..626)
                     /locus_tag="LP468_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL2081126.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKN"
     gene            complement(628..1392)
                     /locus_tag="LP468_001586"
     CDS             complement(628..1392)
                     /locus_tag="LP468_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL2081127.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1400..2077)
                     /locus_tag="LP468_001587"
     CDS             complement(1400..2077)
                     /locus_tag="LP468_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL2081128.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2114..3499)
                     /locus_tag="LP468_001588"
     CDS             complement(2114..3499)
                     /locus_tag="LP468_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2081129.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3709..3793)
                     /gene="ffs"
                     /locus_tag="LP468_001589"
     ncRNA           complement(3709..3793)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP468_001589"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3816..4331)
                     /gene="tadA"
                     /locus_tag="LP468_001590"
     CDS             complement(3816..4331)
                     /gene="tadA"
                     /locus_tag="LP468_001590"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL2081130.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4438..5295
                     /locus_tag="LP468_001591"
     CDS             4438..5295
                     /locus_tag="LP468_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081131.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5376..5711)
                     /locus_tag="LP468_001592"
     CDS             complement(5376..5711)
                     /locus_tag="LP468_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081132.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5778..7148)
                     /locus_tag="LP468_001593"
     CDS             complement(5778..7148)
                     /locus_tag="LP468_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL2081133.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLNFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7226..7762)
                     /locus_tag="LP468_001594"
     CDS             complement(7226..7762)
                     /locus_tag="LP468_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2081134.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8071..9552
                     /locus_tag="LP468_001595"
     CDS             8071..9552
                     /locus_tag="LP468_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081135.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(9655..10362)
                     /locus_tag="LP468_001596"
     CDS             complement(9655..10362)
                     /locus_tag="LP468_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL2081136.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(10441..10779)
                     /locus_tag="LP468_001597"
     CDS             complement(10441..10779)
                     /locus_tag="LP468_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL2081137.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(10890..11852)
                     /locus_tag="LP468_001598"
     CDS             complement(10890..11852)
                     /locus_tag="LP468_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL2081138.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(11867..13198)
                     /locus_tag="LP468_001599"
     CDS             complement(11867..13198)
                     /locus_tag="LP468_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2081139.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(13206..13886)
                     /locus_tag="LP468_001600"
     CDS             complement(13206..13886)
                     /locus_tag="LP468_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL2081140.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(14105..14584)
                     /locus_tag="LP468_001601"
     CDS             complement(14105..14584)
                     /locus_tag="LP468_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL2081141.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(14711..16390)
                     /locus_tag="LP468_001602"
     CDS             complement(14711..16390)
                     /locus_tag="LP468_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2081142.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            16938..18440
                     /locus_tag="LP468_001603"
     CDS             16938..18440
                     /locus_tag="LP468_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081143.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            18453..19115
                     /locus_tag="LP468_001604"
     CDS             18453..19115
                     /locus_tag="LP468_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081144.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(19216..19419)
                     /locus_tag="LP468_001605"
     CDS             complement(19216..19419)
                     /locus_tag="LP468_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2081145.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(19530..20714)
                     /gene="iadA"
                     /locus_tag="LP468_001606"
     CDS             complement(19530..20714)
                     /gene="iadA"
                     /locus_tag="LP468_001606"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL2081146.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(20871..22610)
                     /gene="yfcC"
                     /locus_tag="LP468_001607"
     CDS             complement(20871..22610)
                     /gene="yfcC"
                     /locus_tag="LP468_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL2081147.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(23383..23997)
                     /locus_tag="LP468_001608"
     CDS             complement(23383..23997)
                     /locus_tag="LP468_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2081148.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(24603..24980)
                     /locus_tag="LP468_001609"
     CDS             complement(24603..24980)
                     /locus_tag="LP468_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081149.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(25280..26161)
                     /gene="galU"
                     /locus_tag="LP468_001610"
     CDS             complement(25280..26161)
                     /gene="galU"
                     /locus_tag="LP468_001610"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2081150.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         7714 a         5542 c         4330 g         8580 t
ORIGIN      
        1 ctattttttc ctaagaaaag aaaaacagca aaaaataatt ctaataatac aaaaaataag
       61 ataaagctat gcatgaaaaa ttcttctgga agtacattga tgattggatc agtaacggga
      121 tcgaataacc agtcatcgtt gttgaaaaac gtttcatgaa aaaggataaa aaagcgatca
      181 aatcctatca tcatgaaaaa accgaaaaca actggcagta acatgccgat ttgaaacgga
      241 cgaatcaacc gccaaagccg atcattcttt tgcaaatatt tgataaacaa aatactcggg
      301 atcaaagtga tgaaaaacac agcataatcc actaaaaaca aaattttcac ttcataaaag
      361 tgatgggctc cgctagcaga aactgggaaa tctggcaagc tgaggatggt tttgaaggga
      421 ttattgagat aattcattag gtgatcaaaa tttttcagta acgtctcttg atctaaagaa
      481 gtataatcca aaatttgcaa atgtccgata tcaaatacgt atagtggtcg aaagttgatc
      541 gtcacaccaa ctgccagact gatcagtgtc agaaataggc tgaacaatcc agcatattcc
      601 atccactgcc atctcgaatt tttcatatta gaagctccat tcatccagtg attgtttcac
      661 ataggtagct gggataggca acccaggtac atcttcttct tttgtaaaac ctgataaaac
      721 gagcaaagta tctatattat tgcgtatccc agcttggata tctgtttcat agttatctcc
      781 aaccatgatt acttcttctt tttgcagccc taatacttca acggctttat ccataatgat
      841 ggcttctggt tttccgatgt agatcggcgg cgtttgggtt gctgtctcta caaaagagat
      901 gactgaccct gctccaggaa gaaggccgcg ttcagtaggt atattcttat ctgggttcgt
      961 tccaatgaaa gtagcacctt tttgaatagc aagtgttgct ttaactactt tttcataggt
     1021 cagataatta tctaagccta ccactacata gtcaggagcc tcttcttccc atgtaaatcc
     1081 ggcagctaaa atcaagtcaa tcaatcctgc ttctccgata acatagactt ttttcccttt
     1141 tccatctgct ttcataaaat cgattgttgc caaagtagct gtgtagactg tctctggagc
     1201 tacatgaatg tcaaactcat ctgctagacg attagctact gtttctggtg acttagtcgt
     1261 gttattggta acaaacaaga aaggtaattt tcttttttgc aattcttcca caaatcgttt
     1321 accggccggt atgggttgtg tcccacgata aatcgttccg tctaaatcaa ttaaatatcc
     1381 tttatagtcc attcatccac tactcttccc tttttctgat cgtaaatgct gtttttgttt
     1441 tttctacttg tttaggttgt tcttgttttt ttactttttc agaggttttt gctgactctg
     1501 tttttcgatt tttaataacc ggttttttgc gattagatgc gactggtcct tttttctcat
     1561 cgatatacgc acgattatgg ttttttttct tttttcggcg ctgagttgtc ttttcttttt
     1621 taccgccgat tctctcgatg acaaaatacg cacaaccaaa attgcaatat tcgtaaagat
     1681 agtcttccaa ggaatcgatt cgctgatctg gatgcgcccg tcgattatcc gcttggaaaa
     1741 atccttttag gcgtagttgt tcataacccc aatctcctac gatataatca tatcgggcta
     1801 gtacatcact gtaacgttct ccaagctttt ctgcattaaa tccttcacga taatcggaca
     1861 caagccgata atgtctttca cctatcaaaa aattactgtc atctaacagt gtcactagct
     1921 cgcctttgac tttttctgct ttaggctcct caacgatttc ttccaaagca gctgtcagtt
     1981 cttcggtgac tgttgtttcc tgttcagctg atgatttttt cttagcaatt tctgttttat
     2041 gctcaacgtt ctgctgttca ttttgttttg cagacatgcg ttcaccacct atctttttta
     2101 ttataccttg tttttatttg attgggtagt gagctttcaa gtaatctcct accacacttc
     2161 ggataaattc agggaacaaa aattcatttt ttccagcaat ctcaatcgtt ggaaaaaatg
     2221 gaacaaacat caaatgatct acggtagtaa aagtataatt tttattcaga tcgattggct
     2281 tgttcttcca aaagacttga tggttaatag aatcatatgt gattccatta tagaccatct
     2341 gcccaaaaat cttaccgcga aatcccattc ccttcatagg atagttacgt aaaaagttac
     2401 gatttttttc tatttctaaa actaagcgga tcagatcatt tccacccaat gtgacattta
     2461 acaagtgcat cggatgcggc aacgcagtgt gaagctgatc ctgattgacc cgcccttttg
     2521 gaatttcagt taaaaacaga ccactgttta atattgctgc ttccgtcttt cctcgttctt
     2581 tcaccgcctc aaaggctact tggataaacg aatgctcatt gaagatatct agactcagag
     2641 aaaatggcaa atctgctact tctttttctt ttaataattc atgcccacgt tctagataac
     2701 tatttatttc ttgttcatct tctgtaaaag ctgtcattgt ttcggtaggg atggctttgg
     2761 ctgaatgctt aaggattttt ttctcttcat cgatggttaa atggacttca ccgacatact
     2821 gcccgtactt tccagcggct gctatttgga catcattgat tacgtgacct tctctgaata
     2881 aatgatgggt gtgcgatcct aaaataacat caattgctgg tatttctttt gcaatttgga
     2941 aatcatcctg aatcccgaga tgactcatca aaactaaaac atccacttgt gaacgtaaat
     3001 cttcgactaa ttctggcaaa atatcataag gattccgtat gtcccagcca ttcggattat
     3061 aagtaagcgg aaatggagca gtaaatgcaa ttagtccgat tttcgtctgg tgtttcgttg
     3121 taatgatttt atatggtttc gtccatgccg gtggctggag cgtattttta tcgaataagt
     3181 tatccaggat gatatcaaac tcagcatgat cgtataaatg attcaactct tctttggaat
     3241 ttcctacgcc ttcattgttt cctatcgtcg ctgcatcata accaacttca ttcatcagca
     3301 agatattttc ctgtccattc gttgcttctg acaatggatg ccaacgatcc acaaaatcac
     3361 ctagatctac tgcaatcgtt gtcgtttttt ctttcttttc gttttctcgt ttacgttgat
     3421 ccaaaaacct tctgatcctt ggccaatttt ctaaatgaga atgcagatca ttcgtatgta
     3481 aaatcactat tttttccatg taccctctcg cctctcttta tctttatcat accataggca
     3541 gctttttctt ccattgaaac aagctctatt tcagagtttt tcctgccttg aagcaaattg
     3601 tataagtaca atattcgata aatcagtctg gctaaaaaat caggaacatt catttttaca
     3661 gtactataaa aataaaaaaa acagacccga aagtctgttg tcgtttcatt ataatcagac
     3721 acatggcgga acctgcttag tgctgcttcc ttccagacct gacacgcttc acaagcccac
     3781 cattgtccta gcctttcggc aaagaatagt ataccttatt tttcattcgt tgaccagtct
     3841 ttttttaatt tcttttttcg ctggcggagc tttcggaaaa agtcagtcaa aatcatccca
     3901 cattcgtctt ctaaaatgcc accttctaca tatgcttggt ggttaaaccg ctcgtcctcc
     3961 aaaagattca tcaaggtacc ggctgttccg ccttttggat catacgcgcc gaaataaact
     4021 tctgctacac gagacaaaat catcgcgccg ctgcacatag gacaaggctc taaggtaaca
     4081 aaaagtgcag catcttccaa gcgccagctt cccacttttt cacaggcttc cttgattgca
     4141 agcatttctg catgtgtagt agcatcttgc gtggtttctc taaggttata tcctcttcca
     4201 atcacttttc catccaatac aaccactgct ccaatcggaa cttcatgaag catttctgct
     4261 ttctttgctt ctgccaatgc aaggcgcatc catttttctt tttctactgc atcaagattt
     4321 gtatttacca attacccttc cctgcctttg ttttttcttg ttttacttta gcatatgata
     4381 aaaaggctgt aactaacttt tttttctatg gtaaaataaa tacaagaggt gaacaagatg
     4441 aaaatggata aattacttgc tctttaccca caagcacaga aaaaaaactc tccagcatca
     4501 gaagcggata tcctttcttt tgcaattgat gatgctttta tctggatcaa acaagattca
     4561 ttatctcaac aagaaaccag ccttttgaaa gcgttattcc ctgtaatcaa cgatcaaaaa
     4621 aaacacccat ggtatcacta tctttttaaa gatgcttctt gtgttcaaga aaaaagcttt
     4681 cgtttgatcc agcttcacgt cgaatcaaaa ggagaattct taaaaaaaga atggcaagat
     4741 actattttgg aattatttcg ctattctgct gatttctttt tttatacaga cacagatgcg
     4801 ctcttagtcg aacaaataaa ccgtgattat cttgatgcta ctgaaatcaa cggtattttt
     4861 ctatctttag atgctgattt tgatacgaca acgtctgtat tcgttggttc tttccattca
     4921 cctggcaccg acctcgtccc tttgtttgct gaagaaagaa aaattttttt aacagagcaa
     4981 aacaatcttt atactcacag ccgtactttt tctatgcaag atgtggcttt acattactat
     5041 acaaaagata ctgtaaaaga tagtaagttg atcaaaagtt acatagaact gatcaaacaa
     5101 aatgaaatgg aagtgatcat tcaagaatta tggaatgaat taggcaatgt cagctctgct
     5161 gcaaaaacac tgtttcttca tcgtaatact ctaaaatatc gaatcgaaaa atttcaagaa
     5221 cagtctggtt tcaatctaaa aaaagccaac gatttactgt tttgctatct tttattgctt
     5281 catgaacata attaaagata gattaaaggg gttgtgacaa taattttgtc acaacccctt
     5341 atttcgaatg aatagtgttc aaaagctagt ttctcttaca tcattttttc aacaaaatgc
     5401 attagccggt cttttacatc ttcggttgaa tctttgattg aatcaccata aacagagatt
     5461 ttcttttttc ctgatttgat ttttgctaac attcccatca aagaatccaa gtcactatct
     5521 gaaagaccat ctacgatttc tagtaatttt tcatttccat caaatttgtc atagacgaat
     5581 ttttttactt tcgtccgagt agtcatatga tggatctttt ccattacttt tcccgataca
     5641 acgactgctg tcgctacact ggcagcggct gctacgctta atccgattgt tacttttgtt
     5701 gatgttttca taagtatcag ctccttttta tctatctcca tcatagcata gacaaaaaaa
     5761 taaacgaact aatccactca gtgaaatctc aatcctttag ggaaaaagtt ctttactgtt
     5821 ccttttactt gtttcccaaa tccgacaggt atcttatcta atactagcaa aacccatcct
     5881 tgattcccat cacgttgaaa tgtttctcct gctgtgtaag attgccattc cttttgagtg
     5941 atcggcaagc aaggtatatt ctctatcttt tttgtagcaa gcgctaatgc atagctaggt
     6001 tcaaatcgat tctttttgaa atctcctaaa tgcaaacctg tacgtacgac ttttaaacca
     6061 tcgagagaag gggctaactc aggaacttcc caaagatggt cgttgaacac taaaagtctt
     6121 ccagtagctt cataatgaaa atcatttgaa aactccgtcc agagtttttc ctgctctttt
     6181 gtcatttgca ctttactttt ttttcgtgtc ttcttttctt tatgcatctg attttgtcca
     6241 tgaaaattca gctttgcaac aaaatgtcct tcaccctgat ctttatgagg ccatatacgt
     6301 attgtttttt ccaaaccagc tacgcttccc cattcagaac gtcctgaact aacggattga
     6361 gtcaaaggaa tctcctcaat cgttactgga taattttcta caagccagct aatgatctct
     6421 tcattttctt ctggtgcaaa cgtacaagtc gaataaatca gttgtccttt attttttagc
     6481 atttttattg ctgaagacaa aatctcttgc tgacgttttt gacagtatag cggagattct
     6541 tctgtccact cttttattgc atttggatct tttcggaaca ttccttctcc tgaacaagga
     6601 gcatcaacca cgatccgatc aaaaaagccc gaaaaatgag ggacaagttc tgcgggtgca
     6661 tgatttgtca ctattgcgtt cgaaactccc catcgttcta tattttctga taaaatcttc
     6721 gcacgtttcg gaaagatctc attcgtcact aataaccctt tccccttcat ttgagcagct
     6781 aattgggttg atttaccacc gggagccgca cacaaatcca aaactttttc accgggtttt
     6841 gctgcagcag ctgttccaac gatcattgca cttggttctt ggctatattc atacccagct
     6901 tgatggagga aagactttcc attgacagtg ccaagaaatc cctcattgct gtagggagcg
     6961 ggttgtaatt cttcgctatg gtaagtttgg accatgtcca atcctgccgg ttttagtgga
     7021 ttccaccgaa atcctttttt cacgcttcct tgttcaagcg cagaaaaaaa atcggatgct
     7081 tcttcgccta aaagaagacg atattttttg ataaattgct gtggtaacgt tgtcgcttcc
     7141 tccttcattc caatgtttcg ttagacattt tacaatcttt tttacgaaaa ataaaggtgg
     7201 ctgatctact ttttcatgtt gctgcctaag gtgactgttc ctttaagata ttttccaagt
     7261 attcatccgt cacctcgttt ttatcccaaa cagcgttcat catttcaaga aaatcttgag
     7321 aagaatcatc tgagcgcaaa cttcccaatg cattaagcca taccaattca agcgactttt
     7381 cttctttgat cttcgtgtga cctttgacat atgagaaaaa tggccgctta aatagcgaat
     7441 ccatgtctaa atcagatttt gcaatgattt cacgaatact ttcatggata gaaaaaaaat
     7501 ctttcaataa gtagacaatg cttaaaacat catcggaact gcattcagct aagtagtttt
     7561 caaaataaac agtgatttct tctaatatct tctcttttaa cccgctgatt gatttgaaat
     7621 gtgtataaat cgggtatgta gaacaaccgc agaactctgc taactctctt gcagtaattg
     7681 acttcattcc atattcttcc acgtatacca tacttttgaa cagcaaatat tctttactat
     7741 aatttgttac tctccccatc attcttacct ccgtctcttt tcatctaccc ataaataaat
     7801 aacataaata attctaaaaa tattattgat aattatcaaa acatatttag ttatatccat
     7861 taaaaatcaa tttttccgcc ttaaaaacaa gaatatcttg acaaaatacc ctaggaaata
     7921 aacaatagaa taaacaaggt aacaaaaaaa ttaaataacg ttatataaaa aagaaggcga
     7981 cactctgtga gaataacaca gactgaaatg actttccact cacagttttt gtctaactat
     8041 atacaaaaac agaataaaaa ggaggtattt atgctaattg aagcaagaaa aaaagagtta
     8101 cttgttctac aaatggtcat tcaaaaaaat aattgttctt tacaagaatt atccaatgac
     8161 ttacatattc caaaacggac aatcaaagaa ctgatccgaa aaataaatgt atcactcaag
     8221 caatttttat tgattgatga atttatttat tctaatcata aaggagagat ccaaaccaaa
     8281 gaaaccgatc aaactaaaaa gttagctgtt ttttctaagt taaaattatg ctacctaaaa
     8341 gaatccaatc gttttaacta tttgatgtta ctaatcaatt atccacaaac tgctgtacca
     8401 aaaaaatatt tacttgaaca actttatata tcgccctcct atctcgaaaa actgacaaaa
     8461 cagctcaatc attccttaaa aaaattccat ttacggatcc tatctgtaaa aaattgctgt
     8521 actcttgaag gaaatgagtt atctatccgt ctctatcttt acttttttct ttcagataca
     8581 tttggaggta acgattggcc attttcctca cttgaattaa atgcactaaa aatgaacagt
     8641 acagatgagc aaatagaaaa aatttcaaaa caagaaaaaa atatctactt gctgttaact
     8701 ttattcatat tacgaaacaa acaacaggca tattttccaa aaacttcttc tgaaatcact
     8761 gaattgatgg acttattgca gcatacacat gattattcag aatactttac ttctttttca
     8821 gtgagtcgcc cttgtgaaga gacagaaaca gagagagcct actttaatta ttttttctat
     8881 tgtttttttc caaatcaaat ctcttttcga caaaaacagg agattggttt tttattttcc
     8941 acaagcaaaa accttatttg tcgacaagtc ggtcaattga tgacttactt aactcaacag
     9001 tttcctctca accatttaga aaataaaata ccaatttatt tttattttct tgtgttggca
     9061 gttgtttttt tcgaactgtt gggtgaatcc agcagtagtt tttctacact ttgctttcca
     9121 gaagccacgt ccaatcattc tagttctttt atacaggaaa agaaattaag agaaaaaatc
     9181 gatacaattt tttcaaaaaa tggggaaaga aaccaaatca gtcaatacct tagtcaattg
     9241 atccaacact tactacaaac agaaacgaaa gagcagttac tcatccattt gcagataacc
     9301 aaacagttta caggaaatta tcatcttcaa agccatttgc agcagttatt tcgcaaagat
     9361 gctgttaaaa ttaccgcata ttcagaacat gctgatttga tcattacaga tcagcatgag
     9421 aaaatttcag atgaaacgga gactttctat ctggatacaa cgcacaatac agtgttattt
     9481 ggcaagttaa taaaagcggt tcatgaactg tatatgaaaa aaggttatga gaacaaaaca
     9541 aagaggatgt gacaaaattc ttgtcacatc ctcttattcc aaataaatgg tattcaatca
     9601 gctaactctc ggtattagct cagatcaaag cgctgatttc acaacttctt tattttaatc
     9661 tcttcggttg ccgccgaaca ataagatcaa gcgcaacagc tgcaggaatg tcgaaagcgc
     9721 tgctgcaaca taagtcagtg ctgctgcaaa taatacgtgt cttgccatcg gtacttcttc
     9781 ttccgtcagt agtccgcctt cactcaaaat ttggattgct cgccgagacg cgttaaattc
     9841 gactggtaat gtcaccaatt ggaaaagtaa tgctaaagaa aaagcgaaaa tcccgatatt
     9901 gattaacgta gagttccagc taagcaatac acctaccata atcaagggga acgaaatcat
     9961 cgaaccaaag ttagctgctg gaacaagtgc tgcacgaatc ttcaatggga cataacccga
    10021 agcatcttgt accgcatgtc cgcattcatg agctgctaca cctatcgcag caactgaagt
    10081 agactgtgca gttgcttgag acaaactcaa catcttatta cctgaattgt agttatctgt
    10141 gagatctccg gcaatttgtt gaacaccgac attatttatc tgttgacttt gtaatatata
    10201 ttgtgctgct tgtgtaccag tcacattgtt tttgcttctc acttgatcgt attttcggaa
    10261 agtactattg acgtacgctg acgcaattcc ggaaataact aatccaagaa tgaccaaaag
    10321 aaatgtcgga tctaaaaaac catacattcc ataaccatac attttcgttt cactcctttt
    10381 cgtttacttt attttatcat tagtagtagg aaaagaatgt gaaaagacct tgaatattct
    10441 ttaattcttt ttcacaaatt ccgatttcag tttcatcggt ccaaatcctt ctaccttgca
    10501 atcgatatta tgatcgcctt ctactaaacg gatgttcttg acttttgttc cttgtttaat
    10561 ggcacctgac gcacctttta ctttcaagtc tttaatcact gtcacgctat cgccctctaa
    10621 cagacggttt ccatttgcat ctaataccac taatccgtct tctatgacag tttcttgttc
    10681 ttctttgttc cattcgttcc cgcattctgg gcaaatcaac aagcctcgat cttcatatgt
    10741 gtactctgag ccacattctg ggcaatttgg taatgtcatc ttctttctcc tttaaaatct
    10801 ttagtgagca ctattgtaac ggaaaaagaa gatcttgaaa agatacattt gtgattttta
    10861 ctacaaaagg cacgttttcg aacgaagtat cattctgttt ttctgctctt atacgattgg
    10921 catatatctt ggatctcttt atagatttcc tctacttctg ctaaatcttt tgcattcgca
    10981 ccacttgcta atggatggcc tcctccatga tggcgtttag ccaattcatt gatgatcggc
    11041 cccttagaac gtaaacgtac gcggtaatac cctgaaggct gctgaacaaa aatcccccaa
    11101 gccagcactt cgtcaatcac tccaggaagt gaaacgatcg aagctgtctc tgaatcatcg
    11161 attccatatt tatcaagaat ttcttgcgga aggattattc ttcctgcacc attttcatcc
    11221 acctggatat tttgataaag ataaccggaa agtttagcga ctttcatcgg catttgttca
    11281 atctctctgt tcaaagcact tgcatcaaat ggataatttc tcaatatcga agcaatctct
    11341 aatgtacggg acgtcgtgga gggatacaaa aagcgccctg tatctccgac gattcctgca
    11401 taaagtaacc gtgcagcctt aacgttcatc tttaaagatt caggaaacat caaagcaaat
    11461 tctgcaatca tctcactaca gctacttgct tttgtattta cccacacaag atctccataa
    11521 gggtcatcat tgggatgatg gtcgattttg atcagttttt ctgccaactg atatctttga
    11581 tcactgattc tgggtgaatt agctgtatca gtcacgatga ctagcgctcc ttggtagaag
    11641 acatcttcaa cttcttgcat ttctgctaaa aagcgaagcc cttcaatcgt ttcacctact
    11701 tgacgtattt ctttttctgg gaaactttcc cgtaatagtt cggctaatcc tacttgtgat
    11761 cctaatgcat caggatcagg gcgcaaatgc ctgtggataa tgattttatc gtattttttt
    11821 attgtatcta ctatttcttg ctgtactgtc atttcactcc tgctttctaa gaacgttcca
    11881 ttacttgaca aacaacgatt gctttggaaa cgatggtgtt ttcaataaac acttcgatat
    11941 ccagtttagc ggaacgtctg ccgatttcca atacacgtgg acgaatgtct aattcgcttt
    12001 ccaattggat cagccgcaaa taatgtaggt tcacttgttc aatcaagata tttcgttttt
    12061 ggttcatcac cattgttttt tgtgcgacat cagaaatgat ttcgctaagt acgccaaaag
    12121 aaatggttcc aacgccattg accatttgtg gtgctactac gaatttgaac ttagggtttt
    12181 ccaaacgatt tccttcacgg tcagtatcaa tcgtatggat atttccagat atctgatccg
    12241 aaatcgtatc tgcaatctgc ggttgtcgct ggacaagctg catcgctttc attacatctt
    12301 gccgggtaat caagccttcc aatgtcaagt catcggaaac gaccggcatg acttctagcc
    12361 catcccagat catttgatgg ctaacagagg caatactcat tgttttcttt acactgattg
    12421 gttctttcgt catcacccga tcgatgatct ggtttggcga tttccctaaa acatcttttg
    12481 ccgtaacaat ccccatcaaa cgatgatggc ggttgacgac tggaaaacgc gaatgctgcg
    12541 tttcttctga caaacgctga taatcagaaa tcgtatctgt ctgctgcaaa taatgagtct
    12601 tttcagctgg catatagata tcactgacaa gcatgatatc ttttttgatc aattggtcgc
    12661 ttaacgctcg gttgatcatg gttgcgactg taaatgtatc ataagaggtg cgtaagatcg
    12721 gcatttcaag atcatcagct agctttgcaa tctcagcagt cgtattgaat cctcctgtga
    12781 tcaatactgc ggcgccatct tccaatgcta atttttggac ttccgcccgg ttgccgacga
    12841 tcattagtga tcctggcgta atatagcgtt ccatggcatg tttagtcatc gcgccgatga
    12901 cgaatttatt caagaccttg tctaatcctg ccgccccgcc taaaacgtcc ccttcaatga
    12961 tcctgacgac ctcgccaaat gtcaaacgtt caatatgttt ttttaatttg cgttcgatac
    13021 ggatggtccc tactcgttga attgttgaaa ctagtccgac attttctgca tctttgattg
    13081 cacggtacgc tgttccttca ctgacattca attcttttgc gatgcttctt acagaaattc
    13141 gattgccaac aggtaaactt tcaatatatt ctaaaatcaa atcatgtttt gtcgccattt
    13201 tctgcctaca cttccagcgt ttccgagacg ctcattattt ttccttcact atcttccagt
    13261 aactctacaa aagattcggg atcttgttca atgacaggga aagtattgta atggattgga
    13321 actactttct tggcacgaat tgtttgcgca gcctttgctg catcttctgg ccccatcgta
    13381 tagttatcgc caatcggcaa gaaagcgaca tcaatatcga attcttctgc aagcaatcct
    13441 agatcactga aataagcagt atcccctgca tgataaatcg tttttccttc tgcttgaata
    13501 ataattccgc taggctcgcc catatactga acgataccgt ctacttcata gcttgaacta
    13561 tgctgtgcat gtacgaattt taccacgccg aatggaaacg catgttttcc accgatattc
    13621 ataccgaatg aatctactcc tctgctgttc gcataatcag caatctcaac aatactgata
    13681 attgtggctt gattttcttt tgcaatagga atcatatctc ctatgtggtc actatgacca
    13741 tgagtaatca gcaaccaatc tgtctttact tcttctgcag ttaagtctgt caatggattt
    13801 cctgtaataa acgggtcaat catcacgcgt tggccatttt ccatttcaat tgttaaacag
    13861 gaatgtccat gatacgtaat tttcatattt tacacctcgc gttttctctg tatctttttt
    13921 attaaaaacg atttcatcac ttgcacatca atgaaaaaat atagctgcta aatatatttt
    13981 cattggattg atagtacagt atgtacaaag caattgtaac agataataca ggatgcacca
    14041 agtaccaagc agatataatc tcaagtttga ggtctctgct ctgcttagct tctcttctcg
    14101 tcccttaact aattaaatca gcgtaaatag gatggacgat cttttctaaa tcggctactt
    14161 ttatccgaag gcttctcccg atttcaccgc ttgacacaat tacttcttct ttttctttta
    14221 aagaactgtc tgctaaaaaa caataatcag gatgtgcgag ttttattcca ataggggtgt
    14281 ttgctccgtg gggatatcct gtatgcatta atacaaaatc cattccagga aaaccaactt
    14341 tacgatcttt cgtcacttgt ctcgtttttt tgtaatctaa gtgatcgttc aaaggaatca
    14401 atgcgatgat caccccagtt ttgtttcctt tcactacgag agttttacat atcaaagctg
    14461 gatcaatccc tcttttttgt agttcttctg tgaaagattc ttctaccaca tgactaaaat
    14521 caagtggttg atagctgatc ttttgttctt ctaaataacg ttcgactttt gtttgactca
    14581 tcattgattc actcccttta ttctatcgtt tattataaag cgagggatgc tgtattcaaa
    14641 aattatttgt ttttcgcaaa aaaagagcaa gacgagcact ctatagagag gttcatctta
    14701 ctctttttgt ttatttttta tttcgacgtt gagtagcttc cataatgact ggcaagatca
    14761 ctgggcggcg ttttgtttgt tcaaataagt aacggcctaa ttgatctcgg atgtcttgct
    14821 ttaatttgct ccactcaaaa tcattgcttt ctaaatgttt ctcaacgatt gtttcaatca
    14881 tattgctgct ttctttcatc agatcacggc tagcttttac gtaaacgaat ccccgtgaag
    14941 taatttgagg ttttgaaatg attttctttt ctcgccgact gatagtgaca accgctacga
    15001 aaatcccgtc ttctgacaag atttttcgat cacgtaaaac aatgtttccg atatcaccta
    15061 tgcctaatcc atcaatcatt acattttctg cacttgtagt tcctgcaaca ctcatacgct
    15121 tgttcttata ttccagcacg tctccgcgtc cagtaatata gatatttttg tatggcatcc
    15181 ctactgcatg agccaaatct gcatgagcag ctaattcacg atactctcct tgaactggca
    15241 caaaatatgt tggtttcatc aaattgatca ttaattgcaa gtcattagga ttggcatggc
    15301 cagaaacgcg catattctca gagatcaact tcactgttcc accagctcga taaatgatat
    15361 cttccgtttt cgccacgatg gtttccatcg cgatgcttgg cgtagtagtg atataaacca
    15421 aatctccttc ttcaatcttg acattacggt gtgtaccgtt tgccattttt tgcagagact
    15481 tgatgggttc acccattcgg ccagtttcta aaatgatcag ttcttctgga tcatagtttt
    15541 tcatgtcttt caacgtaaca agcagatctt cacttggtaa ttgaagtttt tctaaacgca
    15601 tcgctgtgcg aataattcgt tcgaaatctt gaccagtcaa gacaactttt cgttgtgctt
    15661 tttctgctgc atccaatact tgttgcactc gttgcaaatt acttgctaca caagcgacga
    15721 tgatacgccc ttcccaatat ttgatcgtat caaatacttc atctgctatt tgggcttcag
    15781 aagctacagg ctgaggattt tctgcatttg ccgattcact tagtaaggct aagactcctt
    15841 ctttgccgat ttccgccaat cgtgcataat ctgtttgata cattgggata gccgtttggt
    15901 caaatttaaa atctcccgta taaacgatac taccttcttt tgttttcaga ttgatcccca
    15961 ctgaatctgg tatcgtatga gtggtacgga aaaagctcac tactgtttca ccaaagtcta
    16021 tttctgtatg ctcatctacc acatggaaat ccttaaatcc tttggctgct tcattacgac
    16081 tgacattcaa ttttgctaac tcgatcgtca actctgtccc gaatactggt acagaaattt
    16141 ttgacaacaa gtaaggaagt gccccgatcg catctgcatg tccatgtgtt aaaaagacac
    16201 cagctacacg atcaatgttt tcttctaaat acgtaaaatc agggattacg acgtcgatcc
    16261 ccaacaactc attttcagga tattttagcc cacaatctaa aataaaaata tcctcgccca
    16321 cttctgcgac atacatgttt tttccatttt cacgaacgcc gcctaatggg ataattttaa
    16381 tggtactcac aaacttcacc tcttcttatg acatccaagt ttaaagatgt cgattttctt
    16441 ctttatctaa atatatgagc cattccaatg aagcatatgc aaaatcacta tttctcaact
    16501 tatggagaat cagcaggaaa attaccagca catccgcgtt ctgacagttg gatgggcatt
    16561 ttattttgga tatacttcat taacaaaatg gatcttttgc gaaacgctat agccagaata
    16621 cttatataag tattcagctg ttccccatta ttatacaaca aataaactaa atcgctagta
    16681 tcagcaattg ttagaacaac tatgcacgta aaaatccctc tgtagcatct aggatttctt
    16741 ttgctattcc tctttcattt cttcttcgtc ggtttgaaac atactttttt cattttacca
    16801 cattttttgc aataactata gtgacttttt atatatacag aacctcatgt tgatggtgtg
    16861 caaacagcat aagatttaag ctagctttaa gataggttgt ctattatcaa atgcatctac
    16921 taggagggat gcaaaatatg aattttatga aacgtgcatg gaaaagtaca aaagtaaaat
    16981 ggggacgttc attgttattg tttgccgtgt tcacagccat tcttattttt gtgctagctg
    17041 gcctcacgat tcgaagcgct gcagaagaag cagcgaatca agcacaaaaa gaagttggag
    17101 caacagtgac tttaagtgcc aatcgagaag cttcatttaa aaaacaggaa caaacttctt
    17161 caagcggttc taccactgaa gaacgtccag atccaggcag tttttctctt acaccagttt
    17221 ccttaacgga cgcggaaaaa atagctgaat tagataatgt aaagagttat tcctttgaaa
    17281 gttccgcctc agctatggca aaagatggaa taactgccat cactagttct gattcaagtg
    17341 aagacagttc agaaactact gatgcaggcg gtgaacctgc tggaggaatg ggcgggaatc
    17401 cgcaaatgac tcaagcagac tttcaaatca gtggtgtgtc agcaactgca caaaatagta
    17461 atttttctga tggaacagca aaaatcacgg atggtgaagg aatagatgac agcgacaaag
    17521 gcacaaacaa tgtagtcatt gattctactc tagcagaaac aaatgacctg gcagtcggag
    17581 atactttcac aatcacgagt actgaagatg aagataccac ttatgaaatg acgatcaaag
    17641 gaatttatga atccagcgaa acaagcggca gtatgggtat gaaattcaac ttcatgaatc
    17701 cgtcgaatac actttacact tcttacactt ttgcaaatga actaaatggg acatctgacg
    17761 ataacacgat agattctgct atttacactc tatctgatcc agataaaatg gatgagtttc
    17821 tcaaagaagc tgagaagctg atcgacacag atacatttag cttacaatca aatgattcca
    17881 tgtatcagtc aatgttggaa cctttaaaca acgtggcaag tttttctaaa aatgttgttt
    17941 tactagtggc tgtagccggt attatcatac ttactctgat cattatgatt accattcggg
    18001 agcgtcggca tgagttaggc gtcttgctat ctttaggaga atccagaagt aaaatcattc
    18061 tccaattgtt taccgaagtg gctatttgta tgattcttgc attaggagtt gcttcgctta
    18121 gcggaaacgt cgtcgcgaat gccgtgggac agcagctact tgaccaacag acagaaacca
    18181 cgacacaaaa ccagcaagct cctggcggtg gacaaatgcc aggtaacaga caagaacaag
    18241 gcggtcaacg cgatggtcaa caaggaacca cgaataatcc atttgctgtt tctgatcaag
    18301 tcagcgaatt ggaaatcaat gtcaaacctg cacaattggg actattagcc ggagtagcat
    18361 ttggaatcag tctgttttct gtctttttag cttctatagg gatattaaga ttaaacccaa
    18421 gaaaaatcct attaaactaa aggaggaatt tgatgttacg gacagaacaa ttgggatttt
    18481 ggtatcaaga tccgcaagat gcgctttata aagatgtaga actgaatttc gaagctggaa
    18541 aaatgtacgc tattttagga gcaagtggtt ctggaaaaac gacttttctt tcgcttattt
    18601 ctggactaga tgcaccaaaa gaaggaaagg tatactatca agatcgttca ctgaacaaaa
    18661 tcgggttaag aagttatcgt aaaaatgatg tctcgattat tttccaagct tacaacttgc
    18721 ttccttattt atcggctcta gacaacgtca tagcagcaat ggaaatcact aagaccaagc
    18781 aagagaatta tcgacaagtt gctttagatc gactggctcg tgtaggaatt gatgaaatat
    18841 tagcaaaaaa acaggtgacc aaactttcgg gaggtcagca gcagcgagtc gctatcgttc
    18901 gtgctatctg ctgtgaacat caactaatcg tagcggatga gcctactgga aatctagatg
    18961 aaacaacttc acaagatatc gtcaaacttt tccaagaaat cgcccatgaa caaaatcgct
    19021 gtattatcat cgtgactcat gagattgaag tagcaaaaag ctgtgatgaa gtctttgaac
    19081 taaaaaataa aaaatttcaa aaaatcgaag tttaaaaaac aggataatga tcaaataaaa
    19141 aatccgaacc atatctgtct cgcagatatg gttcggattt tttatttgct tgattcaatt
    19201 agtaataagt ggtttttatt ttttttcgtc ttttcgagaa aacttgtctt tgacttcgtc
    19261 gcctaaattt cgagcttttt ctttgatgtc agcacctagt gattgtgctt tcccttctgt
    19321 ttctttgctc ttgtcgtctg ttgctttgcc gtatgcttct tttccttcac cgactacttt
    19381 atctttcata tctttagaac gtccttttaa atctgccatt gtgcttcctc ctcttagttt
    19441 gtttattgat ctaccttcag ggtaacatca acaacagata cagacaaaca gaacgctcgt
    19501 tttctaaaaa agatagttag agctgttgat taaaaacttt tttcgaaagt cccccatact
    19561 ttgacttctt tttcttggac cattatttct cctttagcga taactgtatc aatatcaagc
    19621 gtttctttat ccaagataca cagatctgca tcagcaccaa tttcgatttt tcctttttta
    19681 tccaatttca atatacgtgc tggattactg gttatagctc gtaaggcgat ttccaaaggg
    19741 atactttctt tttgcacagc ttctttgatc cctactagca atgccttggc acttcctact
    19801 cctaacccta ggaaatgatt gttttcatca aaataaggca agcttccttg tccatctgag
    19861 gtcatcgtga aattatctaa agaaacatct tcctcgatca atcgtttcag tgctttgctg
    19921 aagcgaactt caccatctgt cttctcccaa aaatcaggat cttcgctagc agtgaagtca
    19981 atcgtgccac cacgtttggc aaatgccacg caagcttcaa ataattctgg tgtgcgattt
    20041 gcatgagtag gcaaaaattg tgtgatcgga atttctgttt cttctacgat tcgtgtcaat
    20101 agctctagct ttctttttcc tccgcctaag tggacattga tgatcccagc ttttccggat
    20161 aacatgcctc ctacacgagc atctgctact gcacgagcga actcttcaaa acttggctga
    20221 gaagaacggt gatcggatac tgcgatttct ccgattccga taattttatc aattgtcaaa
    20281 aagtctttga tgatagaatc tgttactgtt tttaccggca atcggtacga accttcgtat
    20341 acataagtgg agattccttc tgcttccaga cctttcgctt tgctgatcaa cgcagtcata
    20401 tctctacctt ctccgtctgt tcccaaacaa ccgacaactg tcgttacacc agctgtagtc
    20461 aattggctca atgtgacttc tggcgttcga ttttgataac cgccttctcc tcctccacct
    20521 aaaatatgga aatgacagtc aatgaaaccc ggggttagta cttttccctc acctgaaagt
    20581 tcttctactt ccactccttc gtagccgcct tctagctgtt cttctacagc caaaatcttc
    20641 ccaccggcaa tcagtacatc catttttcct aagtaatctg gtgcaaacac ttcaatttgt
    20701 cgaatgattt tcatacattt ttcctctttc tttaagtata actgatgata ggatcttaaa
    20761 aaataatcca aacgatagga tctttactcc tttgatttta ccgtaaaatg acggttcttg
    20821 gagtccttat ctactgtttg gattactttt ttatttacag gtctccagta ctactgcaga
    20881 cctattgcaa tggcaatcat gatgaaaata gttcctaaaa caaacaggaa tccttgcatc
    20941 ttgatttgga atcttgccca ttttgcccat tcgatccgtg caacacctag cacaccaatc
    21001 aagctggctg atacgggtgt aaaagcgtcc ataaaacctg aaccaagctg ataagcaaga
    21061 actgctactt gtctggatac acctactaaa tctgccagtg gagccatgat tggcatagtc
    21121 aaagctgctt gtcctgaatt tgatgtaaca accaagttga acaaactttg gaagatgtac
    21181 atcgcccaag caccaatgac agctggaaca ccggtcaacg ccgtcccgat cccatgcaaa
    21241 atcgtattca aagctgaagg aacagatgca tcagatcctc ccaagacaag aagaatccct
    21301 ttggccatac ctactacgat tgctgtacca gctaaatcag ctgcaccaga ttggaaagaa
    21361 gaagcgatgt cattgacttt cattccatct aatttgaaaa gaacagcaat gattccagca
    21421 actaatccca tcacaaagaa ttgagaagcg atttctggaa tgtaatagcc tttttgagtc
    21481 acgccccaaa cgatccagac aaggacaact aacatctcta ataagatcaa tttatgccca
    21541 agcatgaatt ttttattttc atcagatgtc tttttgatat gagaacggaa ataatcatct
    21601 gatttgtaag tcaacgaact ttctggtttt ttacggattt tttctgcata tatcatcata
    21661 taaccagcgg ctaatgcagt aacaactacc cacataatca atcggaatgt cgcaccagac
    21721 aacacgggga ttccagcaat cccttgagcc accgctacgc taaacgggct catccaagag
    21781 gtcgcatttc cgacttgaga tgcgacataa gtcacggtta ctgctacgat cgagtcatat
    21841 cctaacgcaa tgacaaatgg aaccatcacc attgagaatg gaattacctc ttctgccatc
    21901 ccgaatgtag cgccaccgaa tgaaaaagca aagaataata gcggtaaagc taaacgctcc
    21961 agtcccttag ttttactgat aaacgcatag atacctgcgt cgatcgctcc ggtacgcata
    22021 ataataccaa aagcacctcc aacaacaagg atcaatgcag cgatccctac agcagatcca
    22081 tacttatctc cagatactag tccttcaaaa acaaaattta agaaaccaaa gccgccaaaa
    22141 tcatctgttc cccatatttt ggctgtttta tgcaattttt tagaagtatc atagatattt
    22201 tcgccgtact gatcgtaaag cacatcatct gtcaaggaga tttcatctag tttttcctgc
    22261 gtaagatttt tttctccgtc agcaatgact ttttccaatc ctttttccgg aacatccagt
    22321 ttttcacgtt ctgctggatg atcttgcagt tcttctaatt gatcaaacac atacgactta
    22381 tccagctcgt aagcataacg gaaggaatct tgacgtaaaa cagtacgagt acttgtttcg
    22441 ccatttgcat ctttgtattc aatatcttgc gtgctgaact ttcctgctgg aacgacaaaa
    22501 gtcagtatcc atgcaaagat gactacacca aaaataatga catacgtatg gggtgtcgat
    22561 aatttagtga agtcgcgttt cggttttcct gaagaatttg ttttcttcaa atttatttct
    22621 tcctttcttt tttcagtaat tttgatgaat aaaaaatgga taatcaaatg aattatacag
    22681 taaaaatgac atttccacat gaataattta ttagaaaatc acttttttct attttgtttt
    22741 ttttctccta tgtatgatta tttttttctc tttccattta tattaagtat tttatttctc
    22801 tgtttttcct taaaattctt tttttatttt tagattagag aaaatctcgt cctgtttttt
    22861 tcattttaca atcattgaaa aattgaattt cattgcaaaa aaaataataa acacttataa
    22921 atatccatta tctatccttc aatttttgtg tattttattt ctattagaaa aaggtatcct
    22981 gttggacaat tttgttatat caggtaaact tcattgcaat aatgataaca aatgtactat
    23041 aattactttg taaagagttt tggggaagac tctttcatca acgtgtatta agagacaaga
    23101 aagaatccat atggattctt tcttgtctct ttttccacta ctttttattt ttctgacact
    23161 acatattctt ataactcatt tctcataact gtgaaacaac ttataaaaat aacaaacttt
    23221 aaacaaaaca agcttaaaat caaagatgat ccatcttaaa ataactaaaa caaaaaaagt
    23281 agtcgttgtt aatcctcatt aataatcgtt ttcttttttt caaacgctcc atttttatgt
    23341 ggaacattat ttttttaagg aactttgtca acatgtggat aactattttc cacttgtgtc
    23401 ctggactagc tgttttgctg taaaatacaa aacttgctgc agcaaaaaga tcgttgcaag
    23461 agaggctgtt ccgcagatcg ctggatctag atttggcaaa gtcaagactg catcatgtaa
    23521 attggcgtgg ttgtccaaaa ccaaatcagc aaattcaaat aatcgcaaac cactgctatg
    23581 ttgcgatttg atacttcgtg acaaatcaaa tccagtaaca atgattaatg gatgaccatt
    23641 ttctttgatc cactgagcta gttcgatgat tgccgggttt cttccttcat tcgaaagaag
    23701 aagaaaaatg tcttctgatt tgacagaaag ctgatcaata attgcctgtc ctgcaccttc
    23761 tagcgtttca tagacacctc cggctggatt ttcaatcaat atacttggta caagatccgg
    23821 ggtttgatcc caaaattcaa atgctacacc acttagtgtg cggctagcat atatctgcaa
    23881 tctaccacct tgattaattt gtttcgcgat ccaagtgcca gcttgaagca tcagcggctc
    23941 ttctatcctt aatttctctt ccaattggtg ataatagtca aaataacata aactcattta
    24001 tctctcccgc ctagctatac ttgacatgaa tagaaacagc tgcctaatct aaggaagtac
    24061 ataaaaaaac agtagttaga cagtaacaca tgtggtcttt gctgtttcaa acacaaaaaa
    24121 ggcattgaac gaatacgccc aataccttga catagcaaat aaaacaacgt gcagaccatg
    24181 gaaaatatct acataggggt agaattttca ccctagatta ggtacaataa attaggtcga
    24241 tgcactgcat tgactatggc aaaatgatcg gtcagggtgt atgtgtgtga ctggtcattc
    24301 cctgattctt agcgccaact aagggtcagg gagccttttt ttattcagct gtttctatct
    24361 gaatttattg taagtaatct cttatccaag tgcaagcaag aaaatacaaa aaaacattgg
    24421 tatgatttat atatatataa ataacataaa aaaaggaatg gcttatcccg atacaacaag
    24481 cattccttta aaaaagattc ttttatataa gtgaaaaaag cttttttcca ccaattaaat
    24541 aaatctctca tctcaatagt ttatccatta ttttatcttt ttttgcgtat acctactaaa
    24601 tattaccgtc ttcttctcgt tcttctactt tgttcgagag aatctgtact agaaaaagta
    24661 gttgtatgtc taccttttct gcctatccga gactttcttt tcatatatgg gatataaatg
    24721 attagataca gtacagcaaa aaataaagca aatacgcaag cttcccaact acctaacgcc
    24781 aattcaacca tcaaggtagc aaccccaacg gatgctgcat accagataaa aatcagaaac
    24841 gtttcttttt ttctgaccat gcgaaacatg ataaatagac taataagcaa tagtggcaac
    24901 acaaatatcc aattgcttcc ttccatcagc cacttgagta tatcaagcag cgactgtgca
    24961 acagcgacta attttcccat agtgaacaca cacctttttt tataattaaa aaattcgcct
    25021 ttttattcta ctatgaatct tctggcttgg ctttcatttc tcttatgtaa tcattttctt
    25081 ttatacaact taaaaaaaaa ttaaaccatt agcataatat tttctgaatc tattcacgaa
    25141 agtctttttc tatctttcgt tttccacgac tcaactgatc tagagtcaaa aaactaaaac
    25201 gacagttgcg caaatgacgc acaagctgcc gctttaataa caaatagcct ttcattctca
    25261 gcaggccact tatttccagt taactttctg ttcttagctt tttactcaac tggataatat
    25321 atgcacttaa tgaagtccca atttccgaat gttgaagtcc atattcaata tttgtcttca
    25381 tatatcctaa cttatcgcct acgtcgtatc tttttccttt aaactctctc gcatagaccg
    25441 cctctgtctg gttaagagtc tgaagtgcat ccgttagctg tatctcgttt cctgctcctg
    25501 gttcttgagt ttctaatatc tcaaatattt taggagtcag tagataacgt ccgataatgg
    25561 ctaaattact tggtgctttt cccatttcag gtttttctac aaaccctttt actctgcaac
    25621 gacccttttc gctatctgtt ttaggatcaa taattccgta tttagatgtt tcattttctg
    25681 gtacacgcat gacggcaaca gcggaagctt gtgtttcttc ataatccatc atcaattgtt
    25741 gagtcaatgg gatatcatct ttcatcaaat catcccccag catgacgaca aacggttcat
    25801 ttcctataaa tgcttttgct tgaagcacgg catcccccag tcctcttgga tgagattgac
    25861 ggatgaagtg aagattgact tgagtcgttt cttcaactaa agcgagtaat tctgtttttt
    25921 ccttttcccg caaattgttt tccaattcga tatttgcatc aaagtgatct tcaatgggtc
    25981 ttttttcttt tcccgttacg atcaagatgt cttcgattcc cgaatccaat gcttcttcca
    26041 caataaactg gatcgttggt ttatccacga ttggaagcat ttcttttgcc atggcttttg
    26101 ttgccggcaa aaaacgtgtt cctagcccag cggcaggaat gactgctttt ttgaccttca
    26161 cttgct
//
LOCUS       DAFEML010000033        25971 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFEML010000033
VERSION     DAFEML010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.033"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(1273..1938)
                     /locus_tag="LP468_001611"
     CDS             complement(1273..1938)
                     /locus_tag="LP468_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081151.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2118..4100
                     /locus_tag="LP468_001612"
     CDS             2118..4100
                     /locus_tag="LP468_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBL2081152.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="LP468_001613"
     CDS             4104..4742
                     /locus_tag="LP468_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081153.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="LP468_001614"
     CDS             4770..5198
                     /locus_tag="LP468_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081154.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="LP468_001615"
     CDS             5655..6566
                     /locus_tag="LP468_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2081155.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6783..7220
                     /locus_tag="LP468_001616"
     CDS             6783..7220
                     /locus_tag="LP468_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081156.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7315..8199
                     /locus_tag="LP468_001617"
     CDS             7315..8199
                     /locus_tag="LP468_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2081157.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8423..11590
                     /locus_tag="LP468_001618"
     CDS             8423..11590
                     /locus_tag="LP468_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081158.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11610..12155
                     /locus_tag="LP468_001619"
     CDS             11610..12155
                     /locus_tag="LP468_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBL2081159.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12183..12638
                     /locus_tag="LP468_001620"
     CDS             12183..12638
                     /locus_tag="LP468_001620"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBL2081160.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12635..13393
                     /locus_tag="LP468_001621"
     CDS             12635..13393
                     /locus_tag="LP468_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2081161.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13479..14219)
                     /locus_tag="LP468_001622"
     CDS             complement(13479..14219)
                     /locus_tag="LP468_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081162.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14280..15533
                     /locus_tag="LP468_001623"
     CDS             14280..15533
                     /locus_tag="LP468_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2081163.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15855..16082
                     /locus_tag="LP468_001624"
     CDS             15855..16082
                     /locus_tag="LP468_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2081164.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16205..16531
                     /locus_tag="LP468_001625"
     CDS             16205..16531
                     /locus_tag="LP468_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2081165.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16599..17312
                     /locus_tag="LP468_001626"
     CDS             16599..17312
                     /locus_tag="LP468_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2081166.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17622..18473
                     /locus_tag="LP468_001627"
     CDS             17622..18473
                     /locus_tag="LP468_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2081167.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            18594..20459
                     /locus_tag="LP468_001628"
     CDS             18594..20459
                     /locus_tag="LP468_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2081168.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20507..21916
                     /locus_tag="LP468_001629"
     CDS             20507..21916
                     /locus_tag="LP468_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBL2081169.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            22024..22725
                     /locus_tag="LP468_001630"
     CDS             22024..22725
                     /locus_tag="LP468_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081170.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22884..23363
                     /locus_tag="LP468_001631"
                     /pseudo
     CDS             22884..23363
                     /locus_tag="LP468_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            24211..24786
                     /locus_tag="LP468_001632"
     CDS             24211..24786
                     /locus_tag="LP468_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL2081171.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24786..25226
                     /locus_tag="LP468_001633"
     CDS             24786..25226
                     /locus_tag="LP468_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2081172.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25242..25943
                     /locus_tag="LP468_001634"
     CDS             25242..25943
                     /locus_tag="LP468_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2081173.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         8766 a         4222 c         5360 g         7623 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataagggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tctttttatt agaactaaat caacagtagt ttaattacta
     6661 cttgatttag ttctttttat tttaaaaatt ttttttactt agaatccagc gaccctagat
     6721 atttttctgt ataatcttaa ataaagaaaa caatatcaaa aaatgcacgt agaagtagat
     6781 aaatggagtg gttttgcaaa tttcttttat ttctagaagt tattcacgta tacggatttg
     6841 tttttctcac aaataaaaag gcaggaagta caatggatca tttgtatata aaatatattc
     6901 atcaattttc cgttttggtg ttaggcacac taattatagc ggggattgtc gcatttatta
     6961 ttcaaggccg tgacatatta acagtacatc aagagttttt cagttatgca tttggtattc
     7021 ctctgatcgc tataaggtct gataacaaaa agtggaagaa acgctattac attctcttgc
     7081 tatttttgtg tttttatctg ccacctaaga tttttacttt attaggtata caatgcctat
     7141 cattttcttt tatttcctat atcattgttt taattttcct cagtttcata gtatggatgt
     7201 tttatcttgt caaaaaataa atgaatgttt catgaacagt acttcatcac agcctaattt
     7261 ttttctttat gctatcgtta tattaaagaa atcaatcaga agggaaagaa agtgatgaaa
     7321 aaagttttat tagtggtaaa ccccagttca ggcggtgaac aagcaaagga atttgagcaa
     7381 ttagcgatag caaaattgga atcggtgttt gatgaagtgg tcgtcttgca tacaaaaaaa
     7441 gcaggggatg caaaaaactt tactcgcgaa gcggctacgg aagggtatca tagtgtgttt
     7501 gtcatgggcg gagatggaac agtcaacgaa ggaatcagtg gaatcgctga acaagaacat
     7561 cggccaaatt tcggattttt cccattgggt acggtgaatg acttggctcg agcattaggg
     7621 ataccgctag aacctgagga agcgatcaat catttttcga ttgaatcagt caagccattg
     7681 gatattggaa aaataaatga cgactatttt atgaatgtcg tcgcaattgg ctctatccct
     7741 gaatcaatca atgatgtaga tgcggagaag aagacgaaat ttggaaaact agcttatttc
     7801 atgtcaggaa tcaaacagtt agcttccaca caatcctact cgtttcacgt agaagttgat
     7861 ggaaagaagg aagaaattga gagcagtacc ttgctgatag gactaactaa ctcagtcggc
     7921 ggttttgaaa cattacttcc aaatgcaaaa gtggatgatg gtaagctcca tttggtttat
     7981 ttaaaagatt cttctttgat cgatacgctt aaaacattgc cagacctatt aaaaggagta
     8041 gatgaatcta cgaaaaatct agcctacctt acttgtgagc aattagttgt gtcattagct
     8101 gatgaggaag aattgacgac gaatgttgat ggagatgaag gggataaatt acctgtgaca
     8161 atcaaagtat tgccctcaca tttacaggtt tattgttaaa atggaggttg tgaccgagga
     8221 gttggcggga gaacaccgct tgttcgggat aagggactgt gacaagactt ttgtcacagc
     8281 cttttttttg tacaaaaaag aaatttacac ctaatagaaa aatttttcca taaaaataca
     8341 tattttaaat atgaaagtac aattggaaat agattaaaac gataaaataa aattgtcaaa
     8401 acgtcagaga ggatggtgga gaatgaatca atgtgtaaaa aagctgattg cgtcgatttt
     8461 gtttgtcttc cctctcttga tggtgacatc cgtttttgcc gatgtagaga aaacaaacga
     8521 atcaacgcaa tcagagaatc aaagttttga caagactact ttttcagaag aatcgattac
     8581 ttctgaaact acagaatctc aaagtgaggc ttctactaat aaaaggcaag aagaaaataa
     8641 gacaagtgag acctcagaag tagctgaaca aacgtctgat agcagtgaag cggcactggc
     8701 aagagctgtt tcagcggatg ggtacagcga agctgccaca acagaagaac tggcgcagct
     8761 tctcgcagac gaatcagtaa ctaagatccg actgattcag cctttgactt tagacaggga
     8821 attagagatc aaacgagata tcgttattga ttttggtgga ttcgctcaca atttcggcac
     8881 acaccatatt tatatcaatg agatacctca gtcgatcgag ttccagaatt ttaaaggaac
     8941 agctgcacat ccaggtggat tgacaccaaa tatcgatgga aatgccatta tcattgctta
     9001 tatgaccgat ttttggggaa gcagatatca ttttacggga gaaataaaat ttaccgggac
     9061 acttgatttg tatgatgggt ccaaattagg actgatttac gctcctcgtg caactgtcac
     9121 attagatggt gtttccggtg tgttggatgt ccaaccagtg aaggaaggac tgaatgccgc
     9181 tccgggtaaa gcctattttt gtagaagcta tcaattgaat gtgatcaatg gtagtcaact
     9241 ttatggaccg tatctaggga aattctacgg ttttctagat tcaggagatg agactggtag
     9301 tggaaaaaca gcgccaggaa tccatatctt aagcggttca aaggtctctc ttgattatga
     9361 tcgggcagat ggcgttagcg atgaaggaga ggcagtcgat acgctacctg gtaatgtcat
     9421 gtttgaagtc agtggttcgg gaagcgaatt ttcggtaaat acaaagatca atattaccaa
     9481 tgacaacaat cgcggaatca tccaaatgag aggttcagga tcgaaagtca ctgtatcgaa
     9541 tggtgggaaa atcaccatca atacagcaac tacgggcgga tttcgcttgc aaggagattc
     9601 tagtcaaatc catgtatcaa gtggtggaca aatctcggtc aaaatggctg gagatgacga
     9661 tcaacccggg aacaatggga tgcgttttgt aggaaaaggc ctttctttga tcgtagaagg
     9721 agccggatca gttatcgaca tcgataagca gagtgggcgt tccagcgcag ttcgttttga
     9781 gaatggtacg caaaagctga cagtaaccaa tggaggctca ttgagggtaa gaaatacagg
     9841 tgatggcaaa tcttacgtga acagactcaa tcaaggaaat caagcgatcc aattttatga
     9901 cgcttctggt tttctagaaa gtccaggttc agctgatttt acagtcactg gagaaaaatc
     9961 aaatatcgat atacgcgcag attccggagc aactgtagat acaactggag atattgattt
    10021 aaattttacg gcaggtgaaa aaacttattt agtcatggtc gggaaaacag gggaagataa
    10081 gaccggcatc atcagtgggg atgtgttgaa tgtggactta gaatctccta cctattttga
    10141 tttccaaaac aaacggattg gaagcgagac caatggcata ggcggctggg tattccaagg
    10201 aaatggagat tcttctttaa agatcgccca ttcagaaatc gctttatggc gaaaaacagg
    10261 cgcaacattc gataactttg aaaaagaccc ggattatttt tctgatatga cagacttatc
    10321 gatcaatggg accgacttag gcaatttcgt atcaagccct agtgcaggtt taacaaatga
    10381 atttgctcag acaggtgccg gaatgaaaaa ttataatcga atcagtgcca ataatcagct
    10441 cccgatgatt gaatccttaa gagtgccaac gaatgcagat aaaaaaatct atgggcatgt
    10501 cgttgttccc gaaggtgtcg aggcaaagcc aagagatgct tggacaggcg aagtagaagt
    10561 gactttacgt attacttacg cagatacgac gaaatcatct gtagaaatta ctgctctcac
    10621 gcaaggacaa acagatgaaa atgaaggggc aggatataac ccatggggag aaggcgaaca
    10681 aggcggcttg ttcgaagttc aagtacccaa tgatgagaga ttaaaaacgg aggatcaagt
    10741 gcaagttgtt gctgctaaaa aagtaagagg tggccaagaa gtgacagaac tggactctgc
    10801 caaaacgaca gtcgatgtga ttcctcctga acctgctaat ttaagtacca cattgatcaa
    10861 tgcagcttct cgcacgatca caggtacagg tgaagcagga gccttggttt cattgaaaaa
    10921 aaatcaagct gttttgtcag aaacaactat tgatgataca ggggaatttg ttctttctat
    10981 cccagaaaat caactttttg caggagatgt attagaaatt gtattaaacg accaagcagg
    11041 agaagctact gctaagggtg tgcagaacaa gccaagtacc aacgatgaaa ttgggaatca
    11101 caatccaagt gatacgccag ttgtttatca tgatgccccg ccttttgcac ctgctacgaa
    11161 gatcgtagta gaaggtggtc tctcatttct tgccccttcc aaactcgatt ttggtcagat
    11221 caaagcaact ggtttgacac aagaagcatt tggccaaatg gatatacagg aaaaattatg
    11281 gatttatgat cagcgagaaa cgaaaaatcc gtggatctta acgataaaat tatctcagcc
    11341 tttcacaaat gatgcaggat tttctatgca ggatgtccta tatttcaaga aaggagagga
    11401 gtatcaatta gtgaatgaag aagaactgga aattgtcaga ggacaaaatt caacgaatgt
    11461 gcaagcagat tattcagaat atttaaataa cggtcgggcg tttaaacttg tcttaaccaa
    11521 agaaaatcag atagctggta attactcagc agagataaca tggacattag cagatgcgcc
    11581 gacagaataa agatcaagga ggatgattga tgaatcgaat atggaataaa agtcatcgaa
    11641 acaactgctc tttacttatg atccttctcc ttggattcat cctttggcag acacctgtcc
    11701 atgcctccga attcaatttt gcggtagatt ttgaattacc ggctaatcag attgataaga
    11761 acaaaacata tataaatgta aggatggagc ctgggaaaac acaggaaatc ccctacacgg
    11821 tctttaaccg aacagataaa tcagtaacag ttgagacatt gatccactcc gctacgacga
    11881 attcaaacgg tgtgatcgaa tatggagaat caaaaagtaa atttgatgaa acattaagtt
    11941 atgatatgaa aaacttagca aaaacagtgg gagaaataac tgttcctcct caaagtgcgg
    12001 tcactgagac actttcactg aaagcgccag aaaaagagct ggctggtgtg gtcgcaggag
    12061 ggatcacgtt tcaagaaaaa aaagagaacg tttctaacaa aagtacagtt ggtgtcgtca
    12121 atcagttttc tcaagtgaaa gcaatcttga tttgaaatag cgaaaaagag tcttccccag
    12181 atttgaaatt aaaaaaagct tatgcggatc aaagcgatgg aagaaatgtg attaaggcga
    12241 atcttcaaaa tccaaatgct tcttatatgt tcggcttgac tacatcggtt gaaatctaca
    12301 aaaaagaaac aaaagagcct tacctttcaa taaaaaaaga aaaaatagat gtagcaccca
    12361 atacaaattt tgatttactt gtcccattag aaggaaaaaa attagctccg ggacattatc
    12421 aagcggttgt gaagggtgct tggaaagaaa aacgctggaa tctccatacc gattttgaaa
    12481 taactgatga tgcagcggac caattgaatg aaaaggatat tgatttaaaa aatcagccag
    12541 aaacatttga ctggcgatgg ctgatacttg ttggagtcat tcttattggc ttatttgctg
    12601 gattatttat tttaaaagaa agaaggaaaa agaaatgaaa aaaacaattg cattaagtac
    12661 cgttctagct ggaagtctat tattatgtac acaaagtgtt tttgctgaga ataagagctc
    12721 agccactaca gaaggaacga tttctgtgac caaaccagat gctgcaaatc ctgaagacgt
    12781 tgttccagtt cctcctgttg atccaaatga tcctgatact ccttttacac ctgacgaacc
    12841 aaatcaggga acatccggat tactgacgat tgaccaagct ccagatcttg attttggaac
    12901 aatcaagtta ggtacagcaa aaacagtata tgctgcatta caaagcggaa cggacagtac
    12961 tggagcacaa acacaagtac agaatttcgt acaagtaacg gataaaagcg gaaattatgc
    13021 cggttggaaa ttatcagtca aacgaacaga atttattggt acaacatctg atacgaataa
    13081 actaactggt tcaaaggtga aattcaaaaa cgccgtgatt cgaaatagcg caactaatag
    13141 cagtggaatg ccatctaccg tttctggaac tggcgctgaa ggaatcgaaa tcccagcaga
    13201 tcaggcagta gatctagtaa ctgcaggagc aaatgaaggg attggcacat ggatttattc
    13261 attaggagag aatgtggaac aagggagaca atcagtggaa ttatttgttc ctgtatccaa
    13321 ttatgctgta gacaactacg tttcaacatt cacatggtcg ttaacagatg ctcctacaga
    13381 agaggaagcg taaaatcata tcaacgattt cagggagtgg agccgattca aggcccactc
    13441 cctgaaatct gctatgctta cgtctcagct cttattcatc aactcgaagc agttttttgg
    13501 aagtcatgga aacgttcctt tgtcttttca aagatctttc gaccaacgag taaggagtca
    13561 ccgttgaaaa attctaacac ataatgagca gaatcaattt tctgcaattg cgataagttg
    13621 atacagtaag attttaaaag taaaaagtaa gcatactttt ctaactctgt cttcaattgt
    13681 tttaaagaag tattcactaa tttatcttct gtagttgttt tgaccataac ttggtttttc
    13741 aaacctttga tactttcaat atataaaatt tcccgaggat acaggacgag acttccacct
    13801 ttttgatcaa taaagatttt atcgacattt acgatctgct gttctttcca attgatctgt
    13861 tctagcactt gacgaatttg ttcagataaa ttcctgtctt ttctgatata tccaatcgga
    13921 aggattttcc gattgatgat ctctactgca aaattcgtat aagcggtgaa aaaaacaata
    13981 ttactatgtg catttttttt acgtatttgt tcggcgacat caatacctgt gagtgattgc
    14041 ttcaagtcga tatcgataaa gaaaacatcg tgattatcaa tagtgcccaa ctggatcaac
    14101 tgattgattt gagagataga agtgagctgc acgatattct cgatatgatg attgaccaat
    14161 tctctgatga tccattcgct gtgaaactgg ttatcttcta tgataaaata ctttttcata
    14221 tgcaggctcc tattaaaaaa atatgtgtac attttgaaac aaaacaatgg aggaataaga
    14281 tggtcgcaac agtgacactt tatttgacct ttactttgat tttagattta ggtatctatt
    14341 tattcttttc gaaacaactg ctagtaaaaa acagctttgg ttgtatagct ttgatggtgg
    14401 tgacactttt acttcctatc cctaaagtga gctttcctta cctagttggc ttattattga
    14461 tgtttctttt ttattttact acgaaaaacc tgtttatcag ctgtttgatc agtaatcttt
    14521 tttttgctat cactggactc agcttttttc tggtttttga tctgatggat tatttaggaa
    14581 agagacatct tggaacagca agtttttttg cactacttat cgcatttatt ttctatctat
    14641 tagtaaaaag tatagacaaa cagacgagat ttctcaactt gctttttact tatccaactg
    14701 aacactattt tggaggtatt tgtattttat taagctgggg cgtgatttac ttggtattgg
    14761 gaagtgttca cttccgctca tctaattatc tgcttctatc tcttttgtcg atagtcatca
    14821 gttttttttc tttgtttttt tccattatgt tgatcagttt ccaagtaaaa gaaagacaac
    14881 atcaggaatc gcttcaactg tatcaaataa atgaagaata ttaccatcat ctagaggaat
    14941 tcaaacatga ttataaaagt ctactgtttt cattaaaaat tactcttcag gaaaataaaa
    15001 aagaaacgtt ggaattttta gaaatattag aagatcattc tgcagctatt tttgaaaaac
    15061 cgcaaataca acagctaaca aatattgtat ccccagctgt caggggtgtc tttttaaaat
    15121 ttctagaaaa agcagaatcg gagaaaatcc cgatccaagt agttattcct gtcgaagtga
    15181 aaacaatccc gattgatctg gttgttttta ttcgctgttt atctattttt atttctaacg
    15241 cattcgatca tcgtgtagcc gatcagagtc cgattacgat caatctgctg gaagaaaaag
    15301 agggatcacg ttttagtata gcgaacaagg caaatccaac gaatttgacg ctatcggaga
    15361 tggtcaaaag aggaaaaacc tctaaaaaaa atggcgggtt aggtctatac agtgcgaaaa
    15421 aaatgttgga tgtttacgaa aatgcagaac taaaaatcga attttcaaaa cagaatcact
    15481 atttttttgt agaaatgtat ctggcatcta gaaagagcaa atcagcctac tgacttactg
    15541 tcaaaggata agtttgagga aagtctacac ggagatagag acaacaacac agcatattca
    15601 aaagaaacag aagcgtgatg accgttgtca cccttctgtt tcttttgcta tgtagttaaa
    15661 caaagtagtt gacacttccg ctacttagta ttagtacgaa agtatacttc atgatactaa
    15721 gtagataaga agtgaaaagc ggaacccacg atcgtcaaaa tgctaactgc tttgcttaca
    15781 ccagataaag ggaagagcaa tatcgcttat tttaggcgtg gagaagcaag caaatcccta
    15841 cgatcacaaa aaaaatgctg acccagcagt taagagagtt agaacaagat gaaagtatcc
    15901 atcgaaaagc ctataaccaa gtcccgccta aagtagagta ctcgctcacc gaagaaggaa
    15961 aatcattaag agagattcta gtagcgttgt ctgtttggga agaagaacgt atcgaaaaac
    16021 aaaaagcctc aagggaagaa gacacgctac tgcatacaca tggtggctac ctaaattatt
    16081 gattttctat gacatttatt ttaaataaaa gaaaacagga gtttttttaa aagcatcatc
    16141 tattttttat gtaaaaaaat ggtatgatta atcaagtaag aagtgattgg aagaaggcaa
    16201 gcaaatgaat agtatggaaa aagtcaacca gtttagagat gaacgtaatt ggcgacaatt
    16261 tcataacgaa aaagatttgg ctatctctat ttctttggaa gcatctgaat tgttagaact
    16321 ttttcaatgg aaaacgccgg aagaagtaaa agaaacacaa ttagaacgaa tcaaagaaga
    16381 actggcagat gtattgatct attcatacat gatggcagac aaccttcacc tggatctaga
    16441 tgagatcatt gaagaaaaat tgatcaaaaa taatttgaaa tatcctgtag aaaaaagcgc
    16501 aggtgtacga aaaaaataca cagagttgta gaaatgtgtc attcggctgt tggaaagagc
    16561 aaaagaaaaa cagtaaaatg agtctggagg gagagaaaat gaaaaaaaaa ggaaaagcaa
    16621 aaagatggct agtcaatatc ctcttgttcc tcttgttatt agtaggacta gctttgattt
    16681 tcaatgaaca gatcaaggat tattttgtca gagagacagg agataaatat gctatagcga
    16741 atgtaacaaa agaagatctg aaaaagaata acgataaaga tgtcagtttt gactttgatg
    16801 cggtagaacc aatgacgaca gaaggggtca tgaggtcgca aatgagagga acagatctac
    16861 cagtgattgc tagtatcgca gtcccttcag tttcaatcaa tttaccggtt ttcaaaggct
    16921 tggataatac gtcactactt tacggagcag gaacattatc tccagatcaa gaaatgggaa
    16981 aaggaaatta tgccttagca agccatcgtg caacgaaccc tgaattgctg tttacaccgc
    17041 tagaaaattt agagatgggt gccaagatct atttgacaga tttagaaaat gtgtatacat
    17101 acaaaacatt ttttaaagaa aaagttgctc ctacagatac ccaattactg aatgaagtcg
    17161 agggaaaaga aattgtcaca ctaattactt gtggcgacat ggacgccgtc acgcgactag
    17221 ttgtacaagg agaactggaa agtgttacat cgataaaaga tgcgacagat gatatgagat
    17281 ctgctttcaa tctagagaca aaaacatttt aggatactgg gacataagtc gttacagatt
    17341 aaaaacagcc aaaggatatg aatcgataag gaaaaaccaa tttgctgaaa aaaagagaaa
    17401 cgcaaagagg tgcatctctg atttggttgt tttctagata gacttgtgtt ccagtttttt
    17461 tattttttat atgaaaaggc ttgcataaat aaaaattcga tggtatgatg attttgaata
    17521 agaaatggat tgttactgta cggcaggcaa aaccagaatt cagctaagaa acagtaggcg
    17581 aattctaggt ttttttattt ttcttgagag ggcgaagcaa aatgaaaatt gataaaattt
    17641 tgaataacaa tgtcgtcatt tcgaaaaatg gattcgggga agaagtcgtt tgtatgggaa
    17701 aaggactagc ttttcaaaaa aagattgggg acgagatttc gccagaagcg gtccaaaaag
    17761 aatttgtttt aagagattct tttgctaaaa accaattcca gcagctgatg gctgatattc
    17821 cggcagagga gatcgaatgg gtcaaacaag tagtcgaact ggctgaagat aaactaaaag
    17881 ttgaattttc gcctaatatt tatctgacat tgaccgatca tcttcattat gcgatcacac
    17941 gagcaaaaga aaatatccaa ctgcctaatc cattattatt tgaaacaaaa aaattttatc
    18001 cgaaagaata tcaagcagcg aaagaggctc ttttgttcgt gaaacaaaag acgggtgtgg
    18061 aactttctga ggatgaagcc ggttttattg cctttcattt tgtgaatagc caacaaggaa
    18121 acgaagacat gcaagtgacg atgaccgcta ccacaatggt aagagatata ctgagtatca
    18181 tcagtaaatt cttcggcatc gtgttcgatg aagaatcttt gaattatcag cgtatcatta
    18241 ctcatctgca gttttttgcc cagcgttatc tcaaagggga aggatctgac gagcaagatg
    18301 aatttctcta cgcattagtt caaggaaagt atccaaaagc gtttcattgt gtcgaacgga
    18361 tcaatgagta tcttcgacaa acgcaaaaac aggaaatggg gatcgcagag cagatttatt
    18421 taacgattca tattcaaaga gtagtaagtg agaaaaaaag catccaatca taaggattgt
    18481 tactgtatgg caggcaaaac ctggattgaa aaaataggtt cacgaatgtt tgtgactgtt
    18541 tttttcaatc tgggttttta ttttttaaat aaaaaagaaa gaaggaaaaa acaatggata
    18601 atcaagcagt tggtcgtcgt gtatgggaag cggtaggagg acaaaagaat gtcaaaagtt
    18661 tagtacattg tgctacgcgg ttgcgattca gattaaaaga tgaatcttta gcagatacgc
    18721 aaaagttaaa agaagacccg gacgtgatcc aagtcgtaca aagtggcggt cagtatcaag
    18781 tagtgattgg cagtaatgta gcagatgttt atcaatcgat cgtggatgag gaaggtcttg
    18841 cagtttcgga ggatggaaaa gaagagtcca aaaatatttt gaatcgtctg atcgatatta
    18901 tctctagtat atttacacct tttctagggg cgatggcagc cgccggggta ttgaaaggat
    18961 tcttatcatt ggcaacggtg atgggctggc tgacagctga tagcggtact tatcaaatat
    19021 tgtttgctgc agcagatggt gtctttacct tcttacctgt catgcttgct tttacagcag
    19081 ctaaaaagtt caaagccaac cagtttttag cagtagcaat tgctatggca cttgtgtatc
    19141 cagctatcac agcagttgct ggtgcgggag aagctatcag tttctttggg atcccagtga
    19201 ttctttcacc atctggttat acttcttctg tcataccaat cattctagcc gtatgggttc
    19261 aaagtaaatt agagccattc gtaaaaaaag tgattccgca atttctgcaa atgattttag
    19321 ttccgcttgt cgttttagta gtgatggttc cattaacatt tcttgcttta ggaccaatcg
    19381 ggacggttgc cggtaatgct ttaggcggtc tcttcaactc gatttatgga tttagtccaa
    19441 tcgtagcagg tctaatcatg ggaagtttat ggcaagtatt cgtgatgttc ggcatgcatt
    19501 ggggattcgt accgatcatg tttttgaata tcgaacaata tgggtttgat gtattgatgc
    19561 caatgcttct tccagccatc ttggcacaag gtggggctgc tttagctgta gcattgcgaa
    19621 caaaagatac gaaacttcga gcattaggga tttcttctac agtgacttcg ttatttggaa
    19681 tcactgaacc aactgtgtat ggtgtgacat tacctttgaa gaaaccattc attgccgctt
    19741 gtatttctgg aggtattggt ggagctatta tcggattttc cggagtaaaa gctttctcca
    19801 gcagtttggt cagcttattg acgattccga ctttcattaa tacggtggat ggtgtagagt
    19861 caaatgtgac agtagcagta atagctacag gaattgcttt tgttcttgca ttcgtaggta
    19921 cattgatttt aggatttgac gaacaaacac aagacaatca attagaaaac aaacatgcga
    19981 atgcaggaga accgattact tcagcacggc ataccttaaa aagtccttta acgggtaaag
    20041 tactgccatt gagtgaagta ccagaccaag ttttttcttc tggcgtgatg ggaaaaggta
    20101 tcgctattga tccagaagta ggagaactag ttgcacctgc agacggagag atcacgacta
    20161 tttttccaac tggacatgct gtagggatca caacgactga cggagcggag attttgattc
    20221 atatcgggat ggatacagta gaattaaatg ggaatggctt tgagatctta gtcaaacaag
    20281 gggatctcgt caaagcagga gatttattga ttcgttttga catcgaagca attagagcag
    20341 ctggctatag cgtaatcact ccagttgtca ttacgaatac tgatgcattt gccgatatac
    20401 ttgaattaga ccaaaaagag attattgcaa acgaagatgt tctggcaatt gtaaaataag
    20461 gaggaaatca ggatgcaatc acgtttttca gaaaaatttt tatggggtgg agcaactgct
    20521 gccaaatcaa ttagaagggg cttatgatcg agacggaaaa ggactatccg ttgcagatgc
    20581 tatgcctgga ggtaagcagc gctttgcgat tatcggcagt gaagaatttg actggacgat
    20641 tgatcaagaa aaatatattt acccgaatca tcgaggaatc gatcattacg atcgtttcaa
    20701 agaagatctt gccttgtttg cggaaatggg attcaaatgt tatcgttttt cgattgcctg
    20761 gacacgaatt tttccaaatg gagacgaagg tactcctaac gaagcgggat tagaatttta
    20821 tgatcagctg attgatgagt gcttaaaata tgatattgaa cctgtgatca cgatttctca
    20881 ttacgaaatg cctcttcatt tggcaaaaga atacggtggc tggaaaaatc gaaaactgat
    20941 cgacttctat gaacgatttg ctcagacagt attagagaga tacagcagta aagtcaaata
    21001 ttggatgact ttcaatgaaa tcaattcggc ctttcacttt ccagctttaa gtcaaggatt
    21061 agtaaaaagc aatggagcag gagagtacca aaatattttc caagcatggc ataatcaatt
    21121 cgttgcaagt agcaaagccg taaaaatcgg ccacgaattg cgttcggata tccaaatcgg
    21181 ctgcatgatt atctatgcaa caacttacag catcgatgcc aatccagtca atcaggcagc
    21241 aacaatgatc caaaaccaag aattcaattt tttctgcacg gatgtccaag tacgtggaga
    21301 ataccctgca tacacagcgc gtacccataa aaaatatgga gtcgatccgg aaaaattaga
    21361 gcaaacggaa aaagacttcc agttgctaaa agaatatcca gtggactaca tcggatttag
    21421 ttattatatg tctacggcaa tcaatgagac tgatccacaa gcagcaactt cagaagggaa
    21481 cttgctggga ggagtaaaaa atccgtttct tgaggcaagt gaatggggct ggcagatcga
    21541 tccagaaggg ctgagaatcg cattgaatga attatacaat cgttaccaga aaccattatt
    21601 cattgttgaa aacggtcttg gagccattga tcatatggaa gaggatggca cgattattga
    21661 tgattatcgg atcgattatt tacgtcgtca tatcgaagcg atggctaatg cagtagcaga
    21721 cggtgtagat ttgatgggct atacgccttg gggatgtatc gatcttgtca gtgcatcaac
    21781 aggagaaatg agtaaacgtt acggctttat ctatgtggat ctagacgatg aaggaaatgg
    21841 gacactgaat cgatcaaaga aaaaatcttt tgattggtat aaagaagtaa ttgcctcaaa
    21901 tggcgtaaac ttgtaattaa agcagctgaa tgaaaaagaa cacacttctc acatgtgatt
    21961 tgtgttcttt ttttattttt tatgtgctat tcttttagta atagtaaagc aaagggtgac
    22021 gttatgaaaa ggacacgtgt actatacttg gaagtcgcag ataaaattaa agaagatatt
    22081 ttctcaggaa aatatccagt cggttcgatg ttgccgacag aaagtgaatt agaagaactg
    22141 tttcaagtca gcaaaatcac tgtccgaaag gcaatcgaac tgctggcatc agatgaatat
    22201 gtcgcaaaga aaagtggtcg tgggacgacg gttctaagca atcgtcctta caatcgatta
    22261 tccaaagcgg caagctttac gcaaatcttg gagaactccc gatatgaagt ccggaaagaa
    22321 acgctggatt tgcaattggt ccatataaag aaggaagatc ctttgttttc ctttttcggt
    22381 gagcaagctg tttgttttaa gcgcttatat tatttgaaca atcagcctta tatttatttt
    22441 gttcattatc ttccacaaga aatgatgcaa ttcagcagag aagaatttgg caaagaatct
    22501 ttgtatcgtt tgctgacgaa aaaaggatat actattgact cattttctga tgatttctcg
    22561 gcagtatttt taacagaaga agaacaagga attctgaaaa cagacgcaca gatcggcatc
    22621 aaacggatac ggaaatcgtc tacgcaaatt ggggaaatga ttgaatattc ggaggcggtc
    22681 taccatacgg agctgcatcc ttaccatatt gattatgaaa cataaataaa aaaagaggtt
    22741 gtgaaaaagc tgccctgcat caagtaataa gaacagccaa acaaaaatag cttctcatat
    22801 ttttcgtttg gttaggctta ttaccgcaga tacacggctg tttctggatt accatttatt
    22861 ctggataagg gggtgtggca cgattttcag aaggaatcta tgaaccaatc actgtattga
    22921 ttttagcttc gatggtaacc ccattcggct tgacgatcgc ttatttctta gggaaaatca
    22981 ttcgtaaaaa tatactcaat cgtcaagaaa tcgatacatt gaagaccgct tttcctatgg
    23041 ggatctgtca gatcacagag ggatgtttcc ctatcgtatt gaacgacttg gcacgcaatg
    23101 tcatagcaac gggagtcggt gggacagtag gtggcggatt aagcatgttt tggggcgcag
    23161 atagccgtat tccggcatcg ggaatgtttg cagtcgctac gatgaccaga ccatgggcat
    23221 tcattggtgc attgttagct ggttcttttg tcacaggaat aaccatttta ttattgaaaa
    23281 aaccagtaga tccgaatgca gaaatcatcc aagaagaaaa agaggaagaa gacatatctt
    23341 gggatgattt gacaattagt taggagaggc agaatggatt acaagaaaaa agtacaatag
    23401 atgtaccttg agacaggaat ggtatgaaag aatcagagtt agaaagaatc gaatatacag
    23461 attttggttt aggagcgatc gaaactgtcc agagcatcgg caccctcctt gaaatgacga
    23521 tgaaggaaaa atgagaacct ttcgttgtcg aaagggtctg gtatacctta tgtcgaagga
    23581 aaggaaacaa aaaaactttc ctgtactatt ccaaaaagga aagaaagtta ttatacagta
    23641 aaaaaagaaa ttattcttca tgctagagat cagtacacgt tcgagcccaa tatcaaacac
    23701 tagttccagg caggcgcaac aggtgcggtt atcactgaat tttcttccag cagtgacgat
    23761 tcaagtgata tttttacaaa tccagctatt tatcgttaac aaaaagattt ttaggagaag
    23821 ctgatgaaca aaaatgatca aattttgatc gtttagttcg tcggcttttt tatttagaga
    23881 aacatcattt atcagtgaaa cataacacga gaacaaaatg attttttcgt taataaaaga
    23941 aacaagtatt tgttgtttaa aataatacac gttattggca tataggacga aatcccagta
    24001 tcttctataa gtaagtcatt tcatatcgat gaaaacacgt tatttatttt tgttttatct
    24061 ataaaatggc tgaaaaatga tttttttcta aatactatat atagtggcgt ctatcctata
    24121 taccactaaa aaactacaaa atctagtctt ttattttaaa aaaacacgtg tagaatgaag
    24181 atagactttt gagttaggga gtgttttttt atgaaactta ctgttttttg cggttcccgt
    24241 tttggtaata aagaaagtta caaatttatt gcgcaaacgt taggaaaata catggcacaa
    24301 gaagaaatcg aactggttta cggtggttca tactccggga ttatgggagt gattagtaaa
    24361 acagtactgg aaaataacgg aaaagtcaca ggtatctatc cgaatgggct ttttgaaact
    24421 gaattgcctg gaaaagatgt tactacattt attcctacag aaacgatcga tgaaagaaag
    24481 gtattattat ttgaaaaggg agatgctgtc ctcgttttcc ctggaggtct aggtacattg
    24541 gaggaattct cacaacttct ttcttggata gcaatcggtc tgacgcccga caagccaatc
    24601 ggaatattga atattggcgg ttattacagc ggcttgcaac aattattaga aacttttgca
    24661 aaagaggatt ttatggataa aaaatggttg gatcaagtaa tcttttccaa caatccattg
    24721 gaactggtca atgaattacg agcagtatct attaaaaatc agttattatt gaaggaggca
    24781 aaataatgag tcaaatatat ttagcaggac catttttttc agaggagcaa atcgatcgag
    24841 taagtcgtat cgaaaaagcg ttggaggaaa acaaaacagt cacaagtttc tactctccac
    24901 gtcatcacca agaaagcaat tatgaactat tcagcgctgg atgggcgcag gaagtatacg
    24961 aaaaagatat ggaagaactg acaaatgcag aatttgttgt tgctatcctt gactttgagc
    25021 atcaaacaat cgatccagga acggcttacg aattaggtgt ggcaactatg ttgaaaaaac
    25081 cgatgatcat tgtacaagaa gagacggtac ctacgaactt gatgattaca caaagtctcc
    25141 atacgtattt aaaatcagac caagctgtac gtgaatatga ttttgaaaca ttgcctgttg
    25201 aaacttacgt aggcgagtac ttatagaaga ggaagggttg tatgtcagtg attttgattt
    25261 caggaacgat tggtgcaggt aagagcagtt tgacggatat gcttgcaaaa gagattgatt
    25321 ctaaaccatt ttatgaaaat gtcgaagata acgaagtatt gccgctcttt tattcaaatc
    25381 ctgagcagta cgctttttta ttgcaaatct tctttttgaa caagcgattt ttagcaatga
    25441 aaaatgcttt agtgaacgat gacaatgtgc tagaccgatc catctatgaa gatagcctgt
    25501 tgttccatct aaacgctgat ttaggtcggg taacggatat cgaagtacag cagtacgata
    25561 gcttattaga tacgatgcta aacgagttag atgatgttgc tccaaaaaaa cggcctgatt
    25621 tgatggtcca tatcaaagtt tctttggaca cgatgctaga acgtatcaaa aaacgtgggc
    25681 gtgactatga acagctagaa agcgatgaga cgttatatac ctattatgaa acgttgaaca
    25741 cccgctataa tcaatggtat gaagattttg atgtatgtcc taaaatacaa gtggatgggg
    25801 ataaattcga ttttgtagaa aatccagaag atgcaaaaaa ggtgatccgt cagatccaag
    25861 aaaaattagc tgaattggaa ggaaagcctg ctggaaaata ttttacggat aaccagcatg
    25921 caaaaggtca agaattaggc taaaaataaa aaaccaaacg acgggaaaga a
//
LOCUS       DAFEML010000034        25640 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFEML010000034
VERSION     DAFEML010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.034"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            127..3654
                     /locus_tag="LP468_001635"
     CDS             127..3654
                     /locus_tag="LP468_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL2081174.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="LP468_001636"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="LP468_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL2081175.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="LP468_001637"
     CDS             7442..7783
                     /locus_tag="LP468_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081176.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="LP468_001638"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="LP468_001638"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL2081177.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /locus_tag="LP468_001639"
     CDS             9140..11560
                     /locus_tag="LP468_001639"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL2081178.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="LP468_001640"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="LP468_001640"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL2081179.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="LP468_001641"
     CDS             12994..13731
                     /locus_tag="LP468_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2081180.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="LP468_001642"
     CDS             13745..14560
                     /locus_tag="LP468_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2081181.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="LP468_001643"
     CDS             14573..15220
                     /locus_tag="LP468_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2081182.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="LP468_001644"
     CDS             15236..15892
                     /locus_tag="LP468_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2081183.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="LP468_001645"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="LP468_001645"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL2081184.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVDLEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="LP468_001646"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="LP468_001646"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL2081185.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="LP468_001647"
     CDS             18234..18752
                     /locus_tag="LP468_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2081186.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /locus_tag="LP468_001648"
     CDS             18859..19359
                     /locus_tag="LP468_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2081187.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19639..20559)
                     /locus_tag="LP468_001649"
     CDS             complement(19639..20559)
                     /locus_tag="LP468_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL2081188.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20724..21737
                     /locus_tag="LP468_001650"
     CDS             20724..21737
                     /locus_tag="LP468_001650"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL2081189.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="LP468_001651"
     CDS             complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="LP468_001651"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL2081190.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22822..23262
                     /gene="fabZ"
                     /locus_tag="LP468_001652"
     CDS             22822..23262
                     /gene="fabZ"
                     /locus_tag="LP468_001652"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2081191.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23377..24138)
                     /locus_tag="LP468_001653"
     CDS             complement(23377..24138)
                     /locus_tag="LP468_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2081192.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24327..25421
                     /locus_tag="LP468_001654"
     CDS             24327..25421
                     /locus_tag="LP468_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2081193.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25507..>25640)
                     /locus_tag="LP468_001655"
     CDS             complement(25507..>25640)
                     /locus_tag="LP468_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2081194.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8494 a         4441 c         5407 g         7298 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggatttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
    19501 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
    19561 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
    19621 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
    19681 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
    19741 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
    19801 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
    19861 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
    19921 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
    19981 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
    20041 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
    20101 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
    20161 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
    20221 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
    20281 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
    20341 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
    20401 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
    20461 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
    20521 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
    20581 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
    20641 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
    20701 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
    20761 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
    20821 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
    20881 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
    20941 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
    21001 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
    21061 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
    21121 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
    21181 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
    21241 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
    21301 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
    21361 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
    21421 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
    21481 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
    21541 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
    21601 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
    21661 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
    21721 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
    21781 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
    21841 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
    21901 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
    21961 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
    22021 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
    22081 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
    22141 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
    22201 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
    22261 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
    22321 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
    22381 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
    22441 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
    22501 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
    22561 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
    22621 ctgataaaaa tttgatagtc gtaaaaaaat agagaataat agctaaaata acttcttgat
    22681 ttcttaatta ttagtcaaaa tgttttgatt gtcaaactat tttttcttaa attaaaaaaa
    22741 gattgctaaa tatttaggaa tatgatactt tgatagtcaa agtaatgaaa atggcaattg
    22801 cctgaaagaa ggagtttaat tatgtcttac gtattatctg ctactgaagt aatggaattg
    22861 attcctaatc gttatcctat ttgttatatt gattatgtag atactttaga accaggaaaa
    22921 aagatcgttg cgacaaaaaa tgtaacaatc aatgaagatt ttttccaagg tcactttcct
    22981 gacaatccag tgatgccggg tgcgttgatt ctagaaacac tggcacaagc aggttcgata
    23041 cttatcctaa aatcagaaga gtttctagga aaaagagctt atatcggtgg gatcaataag
    23101 gccaaattcc gtcaaaaagt tgttccagga gatgtgctga aatgtcattt tgaaatcacc
    23161 aaaatgaagg gatcagtcgg tacagcgtta tctgcagcat atgtagatga taaaaaagtc
    23221 tgtgagtgcg agttcacgtt catcgtcaac caaaatgctt gactataaaa cctgatatag
    23281 caaaacaaaa ggaagcttac ttgcttttta tgtaaaaaga agacgcctga atcctagcat
    23341 acgttgtcat ctatgcagga ttcagacgtt atttttttat ttttgttttg cttcttgcag
    23401 tatattgatt ttatcgattt ttacttcttc ttttggtttg tctgaactat ctgtttcgat
    23461 atttgcaata gcatccacga catccattcc ttcaatcact tggccgaaga cagtataatg
    23521 gccatctagt gaaggataac cgccgttttt ataagcgtcg atgattgctt gaggatagtc
    23581 gtcttttaaa agaccatcat gcatatcatc tgtattttga acgataaaga actggctgcc
    23641 gttactgtta ggatcttgtg agcgagccat agataacgca cctcttatat tataaaggtg
    23701 gttgttgatc tctgtttcaa atccttctcc ccaaatgctt tcccctccag tgccatcgcc
    23761 tttaggatcg ccaccttgga tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt
    23821 gtagtaaccg tcttttgcat gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg
    23881 aaataatttg attttgattg tgcctttatt cgtcaccatt tcgaccagat cttcattttc
    23941 ggcgacatct ttcgtcaatt gtggtaattc caatgcgttc aaatcgacgc tactggcagt
    24001 cgtgctttcc gcagtagatg tactttttga actttctgta gacgaactag aagaagtcgt
    24061 gttgtttgca gaacaaccag cagcaaacag caatgctgct gctaaactaa tacttaaaat
    24121 aactttattt ttcttcataa ctgttccttt ccaatttact attttgttat ctttaatgat
    24181 aacaaaatag agggaaaata cctacttaaa ttattggaat ttatcattta ttttaaaaga
    24241 aaaagaaaag gtgtagacca tttactttgt gtttgctata atgtaagtgg atacaaaaac
    24301 gaaaagatgc aggaggaaat ggtaatatgg gaaaattagg aatctcgatt tatccagaac
    24361 ggtcaacatt tgaaaaggac aaagcgtact tggatttagc tcataagtat gggtataaac
    24421 gggtttttac cagtttgctg cagatcaatg atgataaaga aaaagttctt tcagaattta
    24481 aagaagtagt tgattacgcg aatagcctag gcatggaagt aatggttgat atcaatccag
    24541 cgttatttga acagttggag atttcttacg atgacttatc ttttttccat aagatgggtg
    24601 cctacggggt ccgcttagat atcggattca caggagcaga agaagcaaaa atgacgcgca
    24661 atccttttgg tatcaaaatc gagatcaata tgagttcggg cacgaattac gttgacaaca
    24721 tcatgagtta ttcgccaaac acggataatt tattaggttc tcataatttt tatcctcatc
    24781 gatactctgg tttaggatac gaacactttg ttttttgttc agaaaaattc agaaaatata
    24841 atttgaatac gatggcattc gtcaattcgc aatctgctga gtttggccct tggcctacgc
    24901 aagatggctt gtgcacgctg gaagaccacc gagatcttga aattgcgaca caagtgaagc
    24961 atttaatcct tacaggattg attgatgata tttctattgg aaatgcgtac gcaagtgaag
    25021 aagaattgaa agaaatggca gaagcattta acgcggatta tccaacattg aaagtagata
    25081 cggaagaagg tattacagaa aacgaacgaa tctgcttgtt tgataacctt catagttatc
    25141 gaggggatcg ctcagaatat atccttcgtt caacgatgac tcgtgtatac tacaaagata
    25201 aagatttccc gcctcataat acgcgagata tgcatcatgg ggatgtactg attgacaatg
    25261 aagggtacgg tcaatacaaa ggagaaacac aaatcgcctt gaaggatatg aaaaacgacg
    25321 gacgtgtcaa tgttgtagga agaatctccg atgacgaatt attcctcctt gactttttga
    25381 aaccatggtc aagctttaaa ttaattgaaa ataaaaaata gataattagt tattgcagaa
    25441 ataatccgct agaaatagcc agttatttct gcttttttat tttgtttttt tataggttat
    25501 gatttgtcaa attaagctag aataaaatgc ttcttgtaca tagctcaaaa atatttcgat
    25561 tggtgttctg taattcaatg attttcttgg aatatgatta cgttgattgc tgacactgga
    25621 aataaatgtc tgattcactt
//
LOCUS       DAFEML010000035        24897 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFEML010000035
VERSION     DAFEML010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.035"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..129)
                     /locus_tag="LP468_001656"
     CDS             complement(<1..129)
                     /locus_tag="LP468_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2081195.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDS"
     gene            437..1243
                     /locus_tag="LP468_001657"
     CDS             437..1243
                     /locus_tag="LP468_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081196.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1255..2475
                     /locus_tag="LP468_001658"
     CDS             1255..2475
                     /locus_tag="LP468_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081197.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGIVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2465..4051
                     /locus_tag="LP468_001659"
     CDS             2465..4051
                     /locus_tag="LP468_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2081198.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            4090..6228
                     /locus_tag="LP468_001660"
     CDS             4090..6228
                     /locus_tag="LP468_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2081199.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6516..7907
                     /locus_tag="LP468_001661"
     CDS             6516..7907
                     /locus_tag="LP468_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2081200.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLCFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7966..8775
                     /locus_tag="LP468_001662"
     CDS             7966..8775
                     /locus_tag="LP468_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2081201.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8747..9736
                     /locus_tag="LP468_001663"
     CDS             8747..9736
                     /locus_tag="LP468_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2081202.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            9850..10845
                     /locus_tag="LP468_001664"
     CDS             9850..10845
                     /locus_tag="LP468_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2081203.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            10849..11991
                     /locus_tag="LP468_001665"
     CDS             10849..11991
                     /locus_tag="LP468_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBL2081204.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSKK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
     gene            11988..13415
                     /locus_tag="LP468_001666"
     CDS             11988..13415
                     /locus_tag="LP468_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL2081205.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(13482..14771)
                     /locus_tag="LP468_001667"
                     /pseudo
     CDS             complement(13482..14771)
                     /locus_tag="LP468_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(14951..15361)
                     /gene="tagD"
                     /locus_tag="LP468_001668"
     CDS             complement(14951..15361)
                     /gene="tagD"
                     /locus_tag="LP468_001668"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HBL2081206.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            15487..16878
                     /locus_tag="LP468_001669"
     CDS             15487..16878
                     /locus_tag="LP468_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL2081207.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            17011..17958
                     /locus_tag="LP468_001670"
     CDS             17011..17958
                     /locus_tag="LP468_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL2081208.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(17998..19158)
                     /locus_tag="LP468_001671"
     CDS             complement(17998..19158)
                     /locus_tag="LP468_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2081209.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            19323..20498
                     /gene="mltG"
                     /locus_tag="LP468_001672"
     CDS             19323..20498
                     /gene="mltG"
                     /locus_tag="LP468_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL2081210.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            20634..21113
                     /gene="greA"
                     /locus_tag="LP468_001673"
     CDS             20634..21113
                     /gene="greA"
                     /locus_tag="LP468_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL2081211.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            21281..22012
                     /locus_tag="LP468_001674"
     CDS             21281..22012
                     /locus_tag="LP468_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL2081212.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            22009..23076
                     /locus_tag="LP468_001675"
     CDS             22009..23076
                     /locus_tag="LP468_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2081213.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            23083..23715
                     /locus_tag="LP468_001676"
     CDS             23083..23715
                     /locus_tag="LP468_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081214.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            23855..24520
                     /locus_tag="LP468_001677"
     CDS             23855..24520
                     /locus_tag="LP468_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL2081215.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            24548..24841
                     /locus_tag="LP468_001678"
     CDS             24548..24841
                     /locus_tag="LP468_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL2081216.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
BASE COUNT         8481 a         3703 c         4811 g         7902 t
ORIGIN      
        1 agagtcatcc aattttcctt taataaactg cgcttgaacg cctttatatt ctttttcaat
       61 cagccattct tcatcaaaaa ataaatgttt atctgttaat ccgagtaatt ttctagtatg
      121 attatccatt gagagactcc tttggtagga tgacgttttg gtcgactaaa ttttaccaaa
      181 agtgagtctc tttttgagtt taaacgaaga aaaagtgtta gtagaaaatc gccttcgatt
      241 ttccaccaac acaaaatatt atagaacccc ttttttggtt tattgcaatt gtctagcatc
      301 ttctgtaaaa tagaaacgtt agagaaaatc ttgtatcata gaaaattaag aaagaaataa
      361 gaacgcagct cggtaccaaa aatatggtaa aatggcactt gactgtaatt cactgaaatc
      421 gcttggagga acacaaatgt ttaaagattt gtatttattt atgaaagaca tttatcagaa
      481 tagaaaatta ctgctacagt tttcgatcaa tgacttcaaa tcaagatatg caggatcgtt
      541 tttaggaatc ttatgggcgt ttatcaatcc gctatttact gtattgattt attggctggt
      601 atttggtgtt ggactgaaag cacaaatgat cgatgcaaaa tacccattta tcgtatattt
      661 agttaccggg atgattccct ggttcttctt ctcagatgca tttgcatcaa ctacggttgt
      721 ttttcgggaa tatacttatt tagtaaagaa agtcgtattc aatattcgta tcttgcccac
      781 gacgaaaatc ctatccaatc tgtacaccca tttattcttc attctgattg gcatagctgt
      841 cgcgcttata aatggtatat atccttcagc aatgtcttta cagctgattt attatttatt
      901 ttgcatgtgt gctttcttga caggattgac ttggctgacg gcatcgatcc aaccattttt
      961 acctgatatc atgcaattaa ttacgatcgt gctgcagttg atcatgtgga cattaccgat
     1021 attatggagc cctaatcagt ttgattcagg tcttgtaagc atattgaaat taaatccgct
     1081 gtactatgtt gttcaaggtt atcgtgagtc atttttaagt gaagcttggt tctgggagca
     1141 tggaacatat actttgtatt tctgggtttt cacgttagta atgttcgtaa tcggctctgc
     1201 agtgttccgt agattgaaac cacatttttc agatgtgctg taaggagaat agctatgaca
     1261 gaatatgcaa ttagactaaa agatatcaca aaatcttata atatgtacgc aaaaccttcg
     1321 gatcgatttc gtgaagccct caatcctttt aagaaatcct atcatgatgt attttatgcg
     1381 ttgaaaaacg tgaatgtaga aataaaaaaa ggtgagatga tcggtttcgt gggagaaaac
     1441 ggatcgggaa aatctacaat gttgaaaatc attacgggag tactgacacc aacatccggc
     1501 acgatggaaa tcgaaggaaa aatctcagct ttgctagaac taggatcagg attcaatcct
     1561 gagtattctg gctatgaaaa tatctattta aatggaatag ttctaggatt ttcaagagaa
     1621 gaagtcgatg aaatggtcga tgatatcatt gaatttgctg atattggcga ccatatttat
     1681 caacctgtaa aaacctattc aagtgggatg ttcgttcgtc tagcttttgc tgtagcgatc
     1741 aatgtgaatc ctgatatttt gattgtggat gaagcattgg cagtaggaga tcttgaattc
     1801 caactgaaat gtatggaaaa atttacagaa attaagaact cgggaaaaac gattttattc
     1861 gtttctcatg atattagttc gattcgccgt ttttgtgatc gttcctattg gttgaaaaat
     1921 ggagaagttg tcgaatatgg tgatacgatg gaagtaacga cgaattacga aaactttttg
     1981 aagaaaaaat cagttaaaac agtagatcga aataaaaacc aagtagaacg cttcgcagct
     2041 ccagatatcg tagacgtgac gaaagccgaa ttgttggata aaaataaaaa tccagtggat
     2101 atgctggaac aaggagaaaa actatacgtt aaagtaacct atgaagtaaa agacgataca
     2161 atcaaaaatc cagttttagg aattgctctg cgtacagtcg acaattttta tgtgtgcgga
     2221 ctcaatactc tactagatgg tatcaagatc ccttggaaaa aaggtgagaa tatcttttat
     2281 ctggagtatg aaaagttagg tttgttagct ggtgaatatt attttgacgt tgcggtcttt
     2341 gaagaaaatg caacggttcc tttggtatac aagacaaaat acatgaactt gtttgtcagc
     2401 ggttcttata tcggagaagg catcgtggtc ttagaccata aatgggaaga agggactcat
     2461 agcaatgaaa tatgattttg aaatggacct agatgaacaa agcagtgtgg gaaaaattgc
     2521 cgcacagatc aaaccaggaa gtaaagtttt agagtttggt cccggaaacg gtcgattaac
     2581 gaaacatttg atcggagcaa aacaatgtga agtgagcatt gttgagctag ataaggaatt
     2641 attcgatttt gtcagcgaat ttgcccaaga tggattttat ggagatatcg aaagttttga
     2701 atgggcaaac tattatgctg gacagacatt tgattacgtc ttgtttgcgg atgttttaga
     2761 acatttagta gatcctggaa aaacattgaa gaaagtcaga gaatttttga atgaagaagg
     2821 agagatcctg attacattcc ctaacttagc acataattct gtcatgatcg atttgttcaa
     2881 taatcaattg ccttgggctt cttatggtct cctagatgaa acccataatt ctttttatac
     2941 tcatgatggt ttccaaaaag tttttgaaaa agccggatta ttcattaata ttgaagatta
     3001 cttgtacttg gctgtaggag atacagaatt aaaatcaact tatgaagagt tgccggaagc
     3061 tgtacgctat gatttcaaaa tgcgaccatt tggtgaagtc taccaatact ttttctcatt
     3121 gatgaaacat ccagtagtac aaacttccat tgcacagcca caaaactcta attatgtaaa
     3181 agtactagaa gtaacccagc aaacgaaaca agatgaaaca atccaacaaa taccattcaa
     3241 taatttcaca ggggaaaatg agacactaag tttccccgtg tcagaagcaa cagaaagaat
     3301 ggtgtttcgc ttcgcacagc aacctagctt tatcgaattc agtgcagaag ctgctggaga
     3361 aaaactcata tttatcgatt caaatgctgt agtcaaaaca gtaaatgatt gttatttgtt
     3421 tgatgggaaa gaaataccag agttcgctct aacggatatt tctgggaaag aagtgactat
     3481 ccattgtcac tatcgcttta tcggggaatt gacaccaaca atgaaagaat tgctggaaac
     3541 aattcgtcct atggctgaag tcacaaagca gctttctgag aaaaatgatg aattagaaag
     3601 agaaaatcag catcttcttg aggaaaatac aagactagac catacgttaa aaacaaccac
     3661 aaatcgctat tgcacattgt tggaaagtga tgaatggacg atcaaacata gactaggacg
     3721 acgtaagaaa aaaacatcga aaaaaataca agaaaaagag ctttctatat gtattgatga
     3781 gaaaatatgg gatgcagaaa caaaaatatt aaaaatcatc ggatggggaa tcgctaattc
     3841 ggatcgccag ccattgtcct ataagttatc agctgaccaa tcgccatttt tcgaagcaat
     3901 tcctgtttca cgagatgaag tcaatcaagc agaacagctc gcaaaaggaa cagaagcggg
     3961 atttgaatta cgaatccttt gcgagcaaga acgttcattc ttagtggaag cagtagctca
     4021 aaatggtcaa tcatggatca ttgaaatgta aataatgatt aacttataaa gataaggagt
     4081 aaacgaatcg tgcaaaaaaa agaaattgcc gtatttatcg atcaaatcac tcgtgaacgg
     4141 gccactggcg atttgcttat tgtgggctgg gcaattgatg aagtgaccaa agaaatccct
     4201 acgataaagg tagaaaaaga aaatgtgatt gctgaagcaa cacatgtcgt aagattggat
     4261 atcaatcatt tatataatct tgatgttaag acccaaagcg gttttaagat acgtttatcc
     4321 gggaaaatga gaggaaaagc gatcttagat tttcaaacgg caaaacatca aaatggcata
     4381 gctgtgaaac taaatggtaa atacccttat gatgacggca ttgaatcttc atgggaaaga
     4441 aaaaaaagat tactgaaaaa agggataaat tatgcaagga ctcatggcgt aaaaaaaaca
     4501 atccgccggg tcaaactgga attgaaacca ggatcgatcg actatgcaga gtggatcagt
     4561 cgtcacgaga aacctgatct gaaagagcaa aggaaagaag cacaagggtt tgcataccgt
     4621 ccattgattt ccatacttat gcctgtctat aacgttgaaa tcaaatggct cgaaaaatgc
     4681 attgattcgg tattggatca aacgtatgat cactgggaac tatgtatcag tgatgatgct
     4741 tctactgatc cagctatccg aaagtgtctg gaatcctatc aagcaaagga tgatagaatc
     4801 aaagttgttt tccgacaaga aaatggacat atcagtctgg caactaattc tgcgttggaa
     4861 atggcagaag gagaatttat agcgctctta gataatgatg atgaattacc gccatttgca
     4921 ttatatgaag tggcaaaagt gctaaacata catccagaac tggatttgat ctacagtgac
     4981 gaagataaaa tcgatgcaga tggcaatcgc tttgatccgc acttcaaagc agactggtct
     5041 cccgatacat tgatgggaaa taattatatc tctcacttag gcgtatatcg aacaagtatt
     5101 gtgaaaaagc ttggcggttt ccgtaaaggc tacgaaggct ctcaagatta tgatttggtc
     5161 cttcgtgtga cagaacaaat ccctgcagat catatttacc atattgaccg agtcttgtat
     5221 cattggcgga cgatcccagg atcaaccgca agtaatggtg aagccaaaag ttatatctat
     5281 gattctggag tgaaagcatt gacagatgcc ctgtctagaa ggaatatcaa aggaagcgta
     5341 cgtcctggca gaatttctgg attttatgag attgcttatg acgtcttgca agaggatttg
     5401 gtcagcgtga tcattccaac gaagaatggc tatgaagatc taaaaacttg tgtggattcg
     5461 attatcgaaa aaacgtctta tccaaattat gaaatcatta ttgcagataa tggaagtaca
     5521 gatcctaaaa tgcaggaatt atttgcagaa tacaagcatc agctgaaaga ccgatttatc
     5581 gttgaattaa ttgacattcc attcaattat tcacgtatca acaatctggc agcagaaaaa
     5641 gcaaacggca aatacttttt attcttgaat aacgatacag aagtgattga acctgactgg
     5701 atgacagcga tggtttctta tgcacagttt gatcgaatcg gctgtgtagg agcaaaactg
     5761 ttttatccag atgatacaac gcagcatgca ggagtattat taggaatcgg tggtgttgca
     5821 ggacatgcat tgaataacta tgatcgaaca cattgtggtt atttcggccg attggtcatt
     5881 gacgtcaatt acttagcagt cactgcagct tgtatgatgg tcaaggcagc tgacttcaat
     5941 gctgtcaatg gatttgatga aacattagaa gtagcattca atgatgttga cttgtgtttg
     6001 aaagtttatg aactgggtcg ttacaatgtc tatgcacatc aagcagaatt gtatcatttc
     6061 gaatctaaat caagaggtta tgaagataca ccagaaaaac aaagacgttt tgccggggaa
     6121 ataaaaaaaa tgcaagataa gtggccttct tatattgctc atgacccatt ttataacgat
     6181 aatctaacta aagaaggaat cggcgatttt tcattgagac ctgattgatt aaaagaactg
     6241 tattttcatt tttattgatg aaaatacagt ttttttagta tatgaaaatt gtaacttgtg
     6301 accgaagaga tgataggaag aacacccatt cagtaggaag aatgtgatac gatttttgtc
     6361 caactctctg ttaggcagaa atatacatat aaacatacaa tagtcacctt ttctagtttc
     6421 ttttaattta ttttacaatt tggttattca ctaggttttt aaactttgct atggtaagat
     6481 gatagaggca ttattttatg gttaggagtg tatatatgaa taaaaatggg gagtggaatg
     6541 cggcacgtag gatattcatt atcatcatgg atgtacttgt attgaatgtg tcgatctatc
     6601 ttagcttttt gctgaagttc caaggagaag tcccagcaag aaacttagag acctttcagc
     6661 attcagcagt ttttatttcc attatcttta ttgcgttgaa tattttgtta ggagcttatg
     6721 tattctatag ccgagtgatc agtgatatcg tcttcattac tgttattgga caggtgctga
     6781 tagcattggg gatcatggta gttacttttg ctggacgttg gtttgcattt ccgcgtggcg
     6841 tcatcgtgct ctcgtttata cttggcacga tattacttag cgtttatcgg atagttgttt
     6901 ataaactata cttaagagtc agtcgtgata agaaagtcct tatcgtaggt ttggagaaag
     6961 atgtcgcacc agctatccaa aactttcaat ctaagaaaaa caacaaacat aaagttgaag
     7021 cagtagtgat cgacaagtat tacgaaaaca caaaaaaatt gattgatgat atcgatattg
     7081 tctacttggc ttctaaaatc ccagaagacg aaaaaatcaa tatttatcaa ttagtaacta
     7141 aaaaagagaa gaagctattt ttaaatacaa cttttgaaaa tttaacgatg atcaatccga
     7201 acatcatgaa tttcgaagat gaaagtatca ttgaagcttc cggtttcaaa attcagccgg
     7261 aatatgaatt attcaaacgt ctttttgata tcatcgtttc gcttatttta ctgattcttg
     7321 cttcaccttt tatgctaatc acagcgattt tggtaaaaac aacttcacct ggaccaatta
     7381 tttataaaca agtacgtatt acgaaaaatc aaaaggaatt ttcaatctat aaatttcgtt
     7441 ccatgagtgt aacagctgaa gcaaaatcag gaccggtctt ggcaaagagc aatgatgcac
     7501 gtgtgacacc agtaggcaaa tttatccgtg ccgtacgttt tgacgaatta cctcaaatct
     7561 ttaatgtatt gaaaggcgat atgtcgatcg tcggaccacg tccagaaaga ccatttttcg
     7621 ttgatcagtt caatgaagaa aatccttatt attatttaag acacaatgta cgtgcaggga
     7681 ttaccggata tgcacaagta tacggaaaat atgtatcaga ttataatagt aaactatgtt
     7741 ttgatttgtt gtatatcaaa aagtattcct tactattaga tttgaagatt ttacttcaaa
     7801 caatcaaaat cttatttgat aagatgtcct cacaaggact agatgaagat gaaaatatcc
     7861 gttcgttagc agaaatcgac ttttcacaag agaaaattta tcgctagatg ggaaaaattt
     7921 tgagcaaaga agtaggagag aacattggaa aataaaaata taagtatgct gctttcttta
     7981 tatgataaag aaaaaccaga gtatttaaag gaagcattaa ctagtatttt tgagcaaaca
     8041 gtaatgccaa aagaaattgt attagtttat gacggcccta taaatgaaaa acttcaagta
     8101 gttgtcactt atttccaaca aaaagatcct cacttgttta cagttgtaaa attagaaaaa
     8161 aatcaaggat tggggattgc tttagcaatt ggattagaac atacgaaaaa tcgcttagta
     8221 gccagaatgg atacagatga tatcatggaa ccccaacgat tagaaaaaca attagagatc
     8281 ttccaaaaag atccagaaat agcgattgtt gggagtaata ttgaggaatt tactggcacg
     8341 cttagcaatg ttatcggaag aaggattgta cctgaatata atgatgaaat ccgtgtgttt
     8401 tcgaaaagaa gaaatccctt taatcatatg acagtcatgt ttgataaaaa tgctatttta
     8461 gaagtgggaa actatcgccc attaattgga tttgaagatt attatttgtg ggtaagactg
     8521 ttgaaggcgg gatataaagg gtataatatc caagagattc tagtccatgc tagagcaggt
     8581 gctgacatgt atgctagacg tggaggaagt aaatatcttt taccaggaat taaaggccga
     8641 tatcgcgtat ggaaagatgg tctaggatca ctaaaagatt ttctgatagt tatttgcgga
     8701 catcttgtaa ttagtttatt accgaataaa attaggggaa aagtatatga atcaaaactt
     8761 agaaaaacaa actaaacttt ctataatcat acctttttac aatgcaaaaa atactttaaa
     8821 aagagctgta gacagcgtct taacgcaagg ttatcccaat attgaaatct tgttaattga
     8881 tgatggatct acagatggta gtagtgacat tggtgacgaa attgctaatc tagagagtaa
     8941 agtagcatgt tatcacttgg aaaacgctgg tccatcagtt gctaggaatt gtgggataaa
     9001 agaagcaact ggaaatttgg taggattttt agatagtgac gattattttt tacctgattg
     9061 ttttaataat gttttgaaag actaccatag gaattacccc gatatcattg cttttggatt
     9121 aagtaaagga aaaaatatag aaaatgcaaa tttatttgtt cccgaaaaga agattggttg
     9181 ttcaagtgaa gaagcaattg agcaaatgtt tagaagtaag gcagtggatt tttacgtatg
     9241 gaataaattt tttaaaaggg aattattcaa tcatatagtt tttccagaaa ataaattata
     9301 tgaggatatg gttcctatgt atgaagcttt tagagcggct agtaaaattg atattttgcc
     9361 attttcaggt attttttatt atcaaaataa tgatagcatc gtttatcagt cttttaattc
     9421 aaaacagtat gataatattt tgcaaagaaa aatattagtt gatgaagtaa agaaagatta
     9481 tcctcgactt attaatttgg ccaatgctcg attagtagac ggataccttt caacagggtt
     9541 taaaattact ggcaagaatc aaaatcagaa agaaaagcaa aaatattata atcagtctaa
     9601 aagagaaata aaaagtatat attcaaaaat aagaagtaac aatgagatat caattgctaa
     9661 aaaattagct ttatttttat acttaattaa tcctaaaact tattttattt tatataaaaa
     9721 agttctaaaa aaataaagtt tttttcgata tgttattttt tatgtttatt aacttcggaa
     9781 gactaaaatt gttactggta atgatacatt tgtaaaaata aaaaagatga tttttaggaa
     9841 gtgaagagag tgcataaaat tagtgttata gtacccgcat ataacgtaga agactattta
     9901 gaaaactgct tagaatctat ttccaaccag acacattcaa atattgaaat aatagtagtc
     9961 aatgatggtt ccccggatcg aagtggggaa attgcagaag aatataaaaa gaaagatatg
    10021 cgattaaaag tgatacatca agtgaatggt ggtttaagtg cggctaggaa ttctggtctt
    10081 gattctgcaa caggagattt tgtgtgcttt attgacagcg atgattggat agaaccagac
    10141 tatcttgagt tactatattt tggcacgcaa acttatggag cagatatctc ggtgctaaaa
    10201 ataaaaaaga tttcaagttt agaacaacta aaagaacata caattgctga gagaaaatgg
    10261 gaaatatttg atagagaaca agcaatgaaa aacttattta taaataataa aattggctat
    10321 tctgcaaata ataaattatt caatagaaat ttatttgata atataagatt cccactgggt
    10381 aaattaatgg aagataaggc tactacttat ttgctgatcg atcattccga aaaagttgct
    10441 gtcaattcat ctgctaaata tcactattac caaagcccta aaagtatact gagaggaagc
    10501 ttcaatccta gaatttttga ttcttttgaa gtccatgaag atatactaat attcatagat
    10561 aagttttatc cggaattatc aattaatgtt agaactcgct atgtctatga agcaataagg
    10621 atgatgatga caatgattaa aaataactat accaataaag aagattattt acgttctata
    10681 aatattttac aacgctttga aaaagaagtg aaaattgatc ccgacttttc accaaaatta
    10741 aaaaaattag taaagttttt attaataaat aaaaacttgc cttactatat gtcaagtagt
    10801 aagatagcaa gtaaattctt gattaagata gaatctgtga ggtaagagat gaagaatata
    10861 aaaaaatttt tttcaaggaa tattttcccg gtttttatta aaatattacc tattcaaaaa
    10921 aatttaattg tattttcaag ttttggcggg cgtaactatt ctggaaatcc aagagttatt
    10981 tcagagaaaa ttcatgaaaa aaaattgaat tacagaatta tttggttaat caaaaaagaa
    11041 gcgattataa ctgatttacc agattatatt aaaagaattg actccgattc ttttttagct
    11101 gccttttatt tatatacagc taagtattgg atagacgata gtcggaaaac gattaagtat
    11161 gcaaaaagga aaaaacaact ttattttcaa acatggcacg gaacgccttt aaaaaaaatt
    11221 gaatttgatg caaaagataa gttacctaaa cgttacctaa gctatgcgaa aaaagatagt
    11281 gagtcaatta catatttatt atctggtaat cgctatagtt ctaagaagta tgtttcagca
    11341 ttcaatatcg ttccttctaa aatattagaa gtaggaactc ctagaaacga tgaattagcc
    11401 tctagtaaag agcaagtgtt tgacttgaaa aagaaacaaa tcaatgtctt atttgctcca
    11461 acttttcgaa ataatattga ggacaacgga attacgcaac tagaatggtt aggtgtggat
    11521 aacttacgtg aattttttaa aaagcaacaa caagaattaa attttatgac taaatttcat
    11581 cctaatgttc atagtaaatt agcaactgat tctaaaagta tagaatatat gaaaaaacat
    11641 caaattactt taattaatga tgggattcct cttgaaatgc tttttgaaga gatagatgtt
    11701 ttaatcacag attattcatc tatttttttc gattttgcgc taacaaaaaa accaattatt
    11761 ctttttaact atgatgaaaa agaatatagc ttagaaagag gtttttatat acagttaagt
    11821 gagttaccaa ttataagcgt acaagatagt tatggccttg ttgatgtttt taaaaaccaa
    11881 caagaaaagc ttttgaaaag ttctcaagag ttacttgatt atattggaaa ttatgaaaca
    11941 ggagcaagta cagaaaaggt tcttgagttg atagagaggg atataaagtg aaaaaaacag
    12001 taaaagatat attttataat gcgatatatc aagtcttttt gattgtttta cccttactta
    12061 ctatacctat acttagtcgt agaattggtt caactggttt agggatttat gggtatgttt
    12121 tctcaatatc acagttttta atgactgtca ttgctgtggg aatgaatcct tttcgtattc
    12181 gaaatatcgc taaatcaagg aaagataaaa aagcactatc tttacaattc tggaatattt
    12241 actttattca atttttaata ggcttgagtg tttcctttct ctatatagcc tatatttatt
    12301 tttttgatgt aaagtataaa aatttatact taattcaatt gatatttatt gtagggctaa
    12361 cattagatat ttcttggttt tttcaaggaa ttgaagaatt ttcgaaagtg gttattagaa
    12421 atacagttat caaattatca tcggtattgt taataatcat ttttgtttca actaaagatg
    12481 atttgtggat ttacgtgttc attacttcaa ttactaactt tttaggaagt ttagttttct
    12541 ggttaagtat ccacggaaaa gtaggtaaac caatctttaa ctctaatgtt tttaaacagt
    12601 tgtggaaacc agcttttatt attttgactc ctcagttgtt tatgcaagtg tacacaactt
    12661 tagacaaaac gatagttggg tattttgtgg atccaacgga attatcttat tatgatcagt
    12721 ctcaaaaaat tgctcgtatt atattggcag tcttaacatc aattactatt gttatgttgc
    12781 ctaaaatatc taaagcacag gcagagggga aatcagaaaa tattttagtt tacacaaaaa
    12841 aatcttttga ttacacgatt atcattgcat taattctttt tagtgtggtg tttatcaata
    12901 caaaagaatt tgttccatgg ttttttgggg agaatttcaa accgatgaca ataaacatgc
    12961 ttatttcttg tctaattata gttgttagtc caattggtgg agtttttgct aaccaatttg
    13021 caattgctat agaaaaagat aaggagtatg cttatccaat gatcattggt gcgattgtaa
    13081 gtattattgg aaatgtagct tttgtgccta cttatggcgc tgtagcggct acgatcgtac
    13141 tcgtggtagt agaattatta gtctttttct ttagagtatt ttttgtacga aaagaaataa
    13201 aaatatccta tttctttggg aagaacgtta tcttattttt tatagtcaat cttactttga
    13261 ctacttgggc ctattacttt cttccacaat tattctcttc ttcattttta gatatggcaa
    13321 ttaaatcaat aatgattttc attatttatc ttccgtttgt ttattttctt tttccagata
    13381 tacgaaatga aataagaaag attactcgaa aataaaataa tgttgtaaaa aagtagttct
    13441 ttgtcaaatc gggctgataa ggtcatttat gaacaacaaa gttagtaaga gttactagct
    13501 tttaatgcat agctgattaa cctgttgatt agaaaaatcc acaagcgcat attggtaaaa
    13561 ctgcgaaacc cataagcaaa tcgtttcaat gttttgatat gtgtgcgaag attctctaat
    13621 tttgttatta gaatactttt tcgaaaatgc tagttaaaag cctttttcag atatgaaaaa
    13681 ggctttttga gatagtgaag tttcgaggga acttctttgg tcgtttctcg aagtagctag
    13741 ctgtttcttg tgataattgc taagcagctt ttgataaact gcttagcaat tttaagttca
    13801 taagagattg agggtagacg atcaactact tcactttctg ttaaatagcg ccattgaaaa
    13861 ttctgccatt tcttgaatgt tgtgtaatcc aactcgtcat ctgattttag aagtaattta
    13921 tacaaaggtt tcaattgtcg atagtactta gcttgtgaag tgtctttttg attcaactgc
    13981 ttcatcacac gttttcgaac acgatcgaaa aacttgttca agtgttgtcc aatgtgaaag
    14041 caatcaatga tgatttgggc gtttggaaag gactctttga ctaatgaaaa ataaggggca
    14101 ttcatatttg tgacaatgta tcgaaccccc atatgagctt ttcttgtaaa acgcatgaaa
    14161 taagcaatca aatctttttt tctccggctg gacaaaatgt caaagagctt ccctgtctct
    14221 ctattcatac aagaaaagga gaactttcca tgggaaattg aaagagagcg aaactcgtcg
    14281 aatagtaaac aatgaggtaa atagtctagc atctgtcgca gcattgccga tagagcagat
    14341 aatgtccgtt gaaatgtcgt tactgaaaga tcacaacgtt tcgtaagtgt ctttaacgct
    14401 tgacgctcgg tcaactcttc taatatcgtg taatgaactt gtttcgaaat aaaacatgaa
    14461 ggaacgacaa gatacgtatg agcagtaaaa tattttccgc atgattggta gtggtaatgt
    14521 tgttttctaa gacgcaaata ggtttattta ttcccactgc gatttaagat aatcattgaa
    14581 atcttcttgc cgtttttcac gagctgcttc gcagtttctt tacaaaatag acaatgtcta
    14641 aaagtgcgaa ctaatgtacc ttcgattacg atggctttct tgtccttata aaaagttttt
    14701 tgaaaagaat taatttcaat atttttatct ttaatagtga agtgctcttt gatagaacga
    14761 gaaatggata tacaaaatct tcctttcaga ttgatgtttt agacgactct attttatcga
    14821 aatttttgta tgtctgtttt ttttacaaga aaatctagga tcgacagaaa attctatcag
    14881 tcctagaaat tatagagcca tttttttacg tcttatccag atatattgtt ctttcattgt
    14941 ttaaaaaata ttatttatca ctatttaaag aattaagttc gttctttatt tgagttgtag
    15001 agatctcagg tgttcttggt aaataaatta cttgtgcatc tgttagttgt tcaagttcat
    15061 caaattgtcc agcccaatca tcgcccatca cgaaataatc tgcatggtat tcttttatat
    15121 cttttacttt ttgttcccaa ttttcttcag gaataactaa atcaacgtag cgaatagctt
    15181 caagtaactg ttttcttttt tcataactaa aataacattt tttttgtttc gcattccaat
    15241 tgaattcatc tgtagaaagg gcaacaataa gataatctcc atattgtttt gctcgtttca
    15301 gtaaattgat atgcccgtag tgaagcaaat caaaggtacc gtaagtaatt actcttttca
    15361 tctttcacct ctcgaaattc attaatatac attgttagtt tagcattttt ttgttagaat
    15421 tgaaagaacc agtttatcct aaaaaggata agaaatgttt atgagaaata ggtggatgga
    15481 ggaaaaatgt tgaatgaaaa atttttaaaa tatgtgaaag gttggtattt tatttatttt
    15541 ggttttattc taatgttacg agcaataggc ccgtatttac tattacctac tagatatgat
    15601 actttacttt tttggcctgc tggaatagcg ggagttgtct tgatcattat agatgcaatt
    15661 attgcattta gagaaaaaaa tcttaaaaaa tatgattggc tattaattgc ttttattggc
    15721 gcgatgctag taagcagttt aatgaattta aaatatggat atagcgaaaa tatcaagtta
    15781 atcatgtggc aattaatctt tttctttatg atttatcagt ttggcaaaga ctacagtagt
    15841 aacttttttt tcaaagtatt tacttggata ctttcattgg tatggttttt agctaattta
    15901 gtatcattat actggtttgt cattcaatat ggcataaaaa ttccaataaa atataagtat
    15961 tacccagttc gtttagggtg gttaggcaac cgtttatttg gtgtatatac agatccaaat
    16021 tttggtgcgg ttatatcatt aattgtcatc attattgcta tatattattt ggtcacttac
    16081 aagcatttaa atcttctatt taaaatattt tttgcaatta atatttttat tcaattctcg
    16141 tttattgctt tatcgggctc acgcaccaca ttagtttgtt tattaatagc aacttttgtt
    16201 tttagtttct ttacaagtta tagtagtcgt tttcttaaaa ctaatacttt aaaaagatgg
    16261 ctaactgcat tagtagtagg attgctaagt ataattgcga tgtattatgt aacagatata
    16321 actgctcaag catgggcaca tgttccgcat attacagaaa taaaaaaaga tatatctgat
    16381 tcatcaggaa caactagcag caataaagtt gatttaaaac gccctgacac tgatggcggg
    16441 gatgtttcta atttaaggtt tggactttgg aaaagtgcaa ttgaaatatt caagagtaag
    16501 ccgatatccg gcggttctcc aggatactat attgaatacg cacatgataa actaccatat
    16561 acattaatgg gaaaagatac tttaactgct cataatttta ttttcttagt tatggctgct
    16621 acaggaggat taggtctatt gacattgtta accttcttat ttatccaatg ctttaaaact
    16681 ttgcgttatt gtttcacaca accaaatcta gtaaaagata agcacttttt tgctatttta
    16741 atgattctta caatagcagt ttcggcatta tttatcacag aactcatttt ggttagtacg
    16801 ataggttcat ttattttttg gggatatctg ggttctatcc aaaaaactat atctaaagaa
    16861 gaaggagtaa ctaattgaaa ctatttttag gtatataaag tagaaaagaa aactagttat
    16921 cccaacttca acaaatttta tagtttttac aatataaaaa tggtaaacta actttattaa
    16981 gtatgagaat gcataattgg agtgaatttg atggatacta tattgattac tggtggagct
    17041 ggttttatcg gttcaacgct agcgaattat ttgggaaaag aaaacaaaat cgtagtagtc
    17101 gacgatttat caatgggaaa aaaagaaaac ttggatatgg agaaacaagt gactttcatt
    17161 gagggggatg tatcagatcc tcaattgatg gaaagaatca tgaaacagta tcagtttgcc
    17221 tatatttttc atttagctgc tgtagctagt gtggcagatt ctgtagaacg tcctctagaa
    17281 actcatcgtg taaattttga cagtgcgctt ttattgcttg aattggtacg aaaatatcaa
    17341 tctggtttaa aacgattggt atttagttca tcagctgcag tttatggcga tgaaccaacg
    17401 ttgccaaaaa aagaagaatc ggtcatccgt cctttaacac catatgccat cgataagttt
    17461 gcatcagaac aatatgtttt ggattactgt catttatatg atgttccgac tagtgctgtc
    17521 cgatttttta acgtttatgg tccaaatcaa aatcctaact ctccatatag cggagttatt
    17581 tcgattctag tggaccgata caaaaaacaa ttggcaggag aaaaaacaga atttacttta
    17641 tttggtgatg gtagccaatc tagagacttc gtttatatag aagatgttat acaagcactt
    17701 ttacttgttg ctaaggaaga aaaagcttta ggacagcaat tcaatgtcgg tacaggaaaa
    17761 agcactacgc tacttgaatt gattcattca attgatcaaa tcttaggaac agagctagcg
    17821 cttaaatatg aagcggagcg ttcaggggat attcgtgatt ctttagcgga tatttcaaag
    17881 atccgttctt taggttatca acccaaattt gatatattga acggaatgga acgttattta
    17941 aagacagaaa tcgattgaaa caaaaaacca gcatcctgct ggtttttttg tctcgactta
    18001 gctttttaaa ttaacacctt ccatcagttc gtaaatctga tttcttaaat cagtggccgg
    18061 caatttgatg tttttatcag attggatatt actttccatg acgattgcat cttttgtgtc
    18121 ttttttcatc gccgctactg catggaatcg attgatattt ccctgagcaa ggatataatc
    18181 atttccactg taaacaccgc cgctgtaagg atgtttatca ccattatttt gccacaatga
    18241 gaaaagtagt tcttttggta taatatcgcc agacagaaca ctggtaaaga atttgttcaa
    18301 gtcataaaca gacatactta tatttcctgt gcctaattca tttcggatgt ctgtttcagg
    18361 ctcgaccaat gcttttgaat aatcgtcagt tgcagacatt tggtaagata cagcatgctg
    18421 aggggaattt tttacatttt cataaaaatc tgtatgttct agatggagtg gccgaatgat
    18481 ttcttttttt aaaagagttt cataaggctg attcattagt ttgatcaata cccctgtaag
    18541 caatgtataa tttaatggtt cataatgata cgtatcataa ccagtaaatt tcaaatgatg
    18601 aagggcaaac tgaatgatct cactatctga cataggtttt tttggagaag cggttcgatg
    18661 aagaccagag cgcatgtaaa gcatattttt gattgagatt tgctgacttc caggaatctg
    18721 aggataaaat tcagatagct ttgtgtcaaa agttatcttg ccagattgaa tttgttttag
    18781 gataagtaaa gcagtcatcg ctttttggat cgaaccgatt tgatagtaaa gagaaggaga
    18841 attcgattct tttatgcgta gatttgcgta cccatatcct ttttctaata tcactcgatt
    18901 atttttgcgt acataaatcg aaccgatata atctgatttt tgcagtaatt gatcaatttt
    18961 gctggcaagc atctgctcat tagatgttaa attggaagca agttgtgcgg gttccgtttt
    19021 ataaatttgt ggttgaggtt gttttgttaa ttgccatcct gtaatgatgc ctgttgaaaa
    19081 gaagctgaca gccagcaaca aaactgcgag aaaagaaaga gagatctgct gttttttttg
    19141 atgttttcct tttgccatat taaatccttt ctatccattt ttaactattt ttcattgtaa
    19201 tcctcaaaaa gagcatttgc cacttacaat tttgacataa tatttggtaa aataattcac
    19261 ggcagtagaa atttcatgta taataaacag agttacgaag atgatagtaa ggaggagttg
    19321 ttttgtcagg aaacaaacaa cacccaagca aagacaaaaa agaagccagt aaggcagcta
    19381 cagcagatat aatcgacaag cggagaaatc tgcgtaaaaa agaagataag atcgtgagga
    19441 agatcatttt agtgatcgct cttacattat tgattattgg cggatttctc gggtttaccg
    19501 tatatcgtta tgtagatagc gggttgaagc ctttagataa atcggacgac caattagtcc
    19561 aagtggaaat cccaaacggc tcttctaata agcagattgg cgaaattttg gagaaagaca
    19621 atattattaa aagtgggatt gttttcaatt attatacaaa atttaaaaac ttaactggct
    19681 ttcaagctgg ttattatcag ttagcgccta atatgactct tgatgagatt ggcaagcagt
    19741 tgcaagaagg cggcacatct gagccaacaa aagttgcaga tgggaaaatt gccattccag
    19801 aaggctacga catcgatcag attgctgagc gggtagcgaa ggtaacaggt aaagacaaga
    19861 aagaattttt agatttagta aatgatgaga ctttctttaa cgagttgtat caaaaattcc
    19921 cagaattgtt ggaaagtgcc tctaaagctg agaacacaaa ataccgtttg gaaggctact
    19981 tattcccagc tacttatgat tactacacga gtacttcgct taaggatctt gtgattgaga
    20041 tggtgaacaa gacaaatacg gtcatgcaaa actattattc agctatcaaa cagaaaaatt
    20101 tgactgtaca agaagtttta actttggctt ctctagttga aaaagaaggc gtaaaagaaa
    20161 atgatcgtaa aaatattgca caagtcttct ttaaccgaat caaggcaaat atgccacttc
    20221 agtcagatat ctctgtttta tatgcattag gagaacataa agaattggtg acgtatgaag
    20281 atacagctgt agattcacca tacaatttgt ataccaatac cggctatggg cctggtcctt
    20341 ttgacaatcc aagcgaaaag gcaatcaagg cagtattaga accagcagaa aatgactatt
    20401 attatttcgt agcagatacg agcactggaa atgtttattt cgctaaaacg tatgaagaac
    20461 atatggaact agtgcaaaaa tatgtaaata attcttagaa aaacaggggc tagtcattga
    20521 tcatttttag aaaaacattt acattttaag aaaagcgtgg taatcttttt tggactatat
    20581 tcctcaaaag attacctttt gcggtatttt atcgaaaaaa ggagacgtta cacatggtag
    20641 agaaagttta tccaatgact ctagaaggta aagaaaaatt agaaaaagaa ttagaagaac
    20701 taaaaacagt taaacgcgga gaaatcattg aacgaatcaa aatcgctcgc ggtttcggag
    20761 atctttccga aaactccgaa tacgaatcag ctaaagatga acaagcattt gttgaaggaa
    20821 gaatcacaac aattgaaaat atgatccgtt ttgcacaaat catcgataat gacggcgtag
    20881 atgcagatga ggtatcgatc ggtaaaacag ttacgttcat cgagttgcct gatggagatg
    20941 aagaagagta cacgattgtc ggaagtgctg aagcagaccc gttttctgga aagatttcca
    21001 atgattctcc tatcgcgcaa gcattgattg gcaaacgtaa aaatgatgaa gtaaccattg
    21061 ctacaccagg tggcgatatg ttagttaaaa tcgtcaaagt agaacaagcg tagtctgact
    21121 gaaagatcta gagagttcat cttactgatg acgcactcta gatcttttct ctttgagtat
    21181 tgcaggtttc actgaacgat cttacatcta aagtcctata gccaacagtc aaaaaaatag
    21241 gtatgatgaa atgagaatgt gtcaggaggg agaaaaagcg atgaatagtt cttggcgttt
    21301 ttttgtggta gtcgaagcac tgctgctgtt atttgctgtt tggcaaatcg taaacaatac
    21361 tggacttttg cttttagtaa tattcggtat tttcaatata tatctagcta tgcgcaaata
    21421 tcctcgtact aaatttcaaa attttcaatt gatcttaggg agcttggtca ttttttttag
    21481 cttagtcaac agtcctgctt tatggatgat ggttgtattg gccgttttat ttatcgggct
    21541 gaaaggtgta gagatttcag gaatagattt gacaaaaaat gctttttggc gaaaaaaaca
    21601 gatcatgatg gtccaaacag agcaattaaa aacacataat aatgagcgta aaagacagca
    21661 attatttggt aaccaacgta ttggaaacga cgtctatgaa tgggatgata tcaacattgc
    21721 catcatttct ggtgatacta tcatcgattt gggtaataca cttttgccaa aagatgataa
    21781 tattgtgatt gtaagaaaag ggataggcag aacacggatc ttagtacccc tgggagtggc
    21841 tattcgttta gagcatgcga cattagtagg aaatgtcttg tttgaagaag agcagttttc
    21901 cttaaaaaac gaacagatca aaatctgcag cagtgattat gatgaaaatc ctcgcagatt
    21961 gaagatcatt accaatacct tggttggaga tgtcgaggtg atacgaatat gatgggaaga
    22021 atatccaaag caatgctagc tgtttattcg gggattgcgg ctttccttat tattctattt
    22081 tcacttttca cttattttta tgccagtaac caaagtcatt ggtggggaga attgctgcgt
    22141 gcgcgtttat tatacgttcc gcttatcttc catttgatgg caatttcatt aggtgtagga
    22201 ttgatcgtat ttctattgtt atcacttatt caaaaggcaa aatacgggaa aatcgaagaa
    22261 aagcttcgtg cactttcttc tggcaattat gaatccaaac ttttgcatca gccgatccca
    22321 agcgcgtcgg atgatctgta catcaaagat attgatatgg aaattgctaa aataaaagaa
    22381 aaaatgatcg aagtatccag tgaattacag attatgacta gccgtcctca atatgtagat
    22441 ggacaaacca aagaagagat tttagaatta gaaaggcatc gattagctcg tgagcttcat
    22501 gattcagttt cacagcaatt atttgcagcg atgatgatga tgtcggcatt gacggagcaa
    22561 gcagaaaaaa gtgagacacc agaaatgttc cgtaagcagt tgaaaatggt ggcagagatc
    22621 atcaacgctt cccagtctga gatgcgtgcg ctgcttcttc atctgcgtcc agtcaattta
    22681 gaagaaaaaa gtttaaaaca aggcattgag cagttattga aggaattgca gaataaaatc
    22741 cagatttcgc taaaatggga tgtagaagat gtaaaattaa ctagttccat tgaggatcac
    22801 ttgttccgaa tcgttcaaga attgttatca aacacattaa gacatgctaa ggctaatgaa
    22861 ttagaagtct atttgcataa aatagataac aatcttttat tacgtatcat tgacgacggg
    22921 acaggattta atatgaatga aaccaaaacg ggaagttatg gattgaacaa tatcaaagaa
    22981 cgagtagctg gtattggtgg aacagtaaaa atcattagtt ttaaagggca aggtacgagc
    23041 gtggagatca aggtcccttt gatgaaggag gcatagataa agatgataaa agttttatta
    23101 gtagatgacc atgaaatggt acgcttaggc gtctcttctt atttatctat ccaagaagac
    23161 attgaagtga ttggagaagc tgaaaatgga cgtcaaggct atgaaaaggc gatggcactt
    23221 cgaccagatg tcattttaat ggatctagtc atggaagaaa tggatggcat cgaatcaaca
    23281 aaagcaatct taaaagattg tccaaaagcc aaaatcatta tcgtcacaag ttttattgat
    23341 gatgaaaaag tttatcctgc aattgaagca ggagcagcag gatatttgtt gaagacgtct
    23401 accgcacatg aaatagctga tgctataagg gctacgcaac gcggcgagcg agtattggaa
    23461 cctgaagtga caacaaaaat gatggaaaaa atgagtcggc gaaatgatcc agtattgcat
    23521 gaagaattaa cgaatcgaga aaatgaaatt ttgatgctga tttctgaagg gaaaagtaat
    23581 caggaaatcg cggatgaatt gtttatcaca ctgaaaacag ttaaaacgca tgtgtcgaat
    23641 atattagcta agttagaggt agaagaccga actcaagcag ctatctatgc gtttaaacat
    23701 ggtttggtga aataaaaacg atgataaaga ggataatcaa aagctgagaa aataactatt
    23761 atttttcttg gcttttttac aataatgatg cttgcttttg tttttggaaa ggctttgtta
    23821 tactgagaaa agaagatact aaaggaggaa aatggtgaaa caaaattttg caattgtagg
    23881 ccttggacga tttggcggaa gcatctgccg tacactgatc gaagctggac aagaagtact
    23941 ggctattgac agtaatgaag atcgagtcaa tgaatatatg aatatagcca ctcatgctgt
    24001 tgtggcaaat gcacaggatg agatgacact tcgttcatta ggtataagaa atttcgatca
    24061 tgtaattgtc gctattggag aagatatcca agccagtatc ttagttactc tgatggtaaa
    24121 ggaaatgggc gtaccgaata ttttagcaaa agcccaaaat gagtaccatg cccgtgtact
    24181 agagaagatc ggagcagatc gtgtcgtaca ccctgagcga gacatgggga tacggattgc
    24241 acataactta gtatcaaaga atattctaga ctacttagag ctgtcagata aatattcttt
    24301 agcagaaatc cgagtctcca atcctaaatt tttcaacaaa acattagctg aattaaattt
    24361 caggcaacgt tttgacttaa cagtagtcgc catacgaaga gtagatcaaa cggttatcgc
    24421 ttctcctgca gcagatgaat atgttcgcga aaatgataat ctactggtga ttggagagac
    24481 aggcgatgtg gatattctag acgataagat gaatcaatag aaagaaaaga gaaagtaggt
    24541 tgttgggatg gaattaacgg taacgccaaa agcacaaaag tggtttgact cagaaattga
    24601 tctgccagaa acttacggaa tacgtttttt tggaaaagtc tacggcaaaa cagaggttca
    24661 tgatggtttt tcgattggaa tgtcagttga acagccagaa catcctgtaa agaaagtgga
    24721 aatggatggg acactttttt ttatcgagga agcagatgaa tggttcttta aaggatatga
    24781 tttacttgtt gattatgatc ccaacctgga ggagccaacc tatcacttta aaaaacaata
    24841 aaaaaagaga gggtgacaca atttttgtca ccttctcttt tttcttttga aaatatt
//
LOCUS       DAFEML010000036        23658 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFEML010000036
VERSION     DAFEML010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.036"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            258..533
                     /locus_tag="LP468_001679"
     CDS             258..533
                     /locus_tag="LP468_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081217.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            546..2624
                     /locus_tag="LP468_001680"
     CDS             546..2624
                     /locus_tag="LP468_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL2081218.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2784..4670
                     /locus_tag="LP468_001681"
     CDS             2784..4670
                     /locus_tag="LP468_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2081219.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4682..5629
                     /locus_tag="LP468_001682"
     CDS             4682..5629
                     /locus_tag="LP468_001682"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL2081220.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5649..6176
                     /locus_tag="LP468_001683"
     CDS             5649..6176
                     /locus_tag="LP468_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2081221.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6239..6892)
                     /locus_tag="LP468_001684"
     CDS             complement(6239..6892)
                     /locus_tag="LP468_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL2081222.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7024..7866
                     /locus_tag="LP468_001685"
     CDS             7024..7866
                     /locus_tag="LP468_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2081223.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8024..8920
                     /locus_tag="LP468_001686"
     CDS             8024..8920
                     /locus_tag="LP468_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2081224.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8923..9636
                     /locus_tag="LP468_001687"
     CDS             8923..9636
                     /locus_tag="LP468_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL2081225.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9656..10174
                     /gene="msrA"
                     /locus_tag="LP468_001688"
     CDS             9656..10174
                     /gene="msrA"
                     /locus_tag="LP468_001688"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2081226.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10171..10398
                     /locus_tag="LP468_001689"
     CDS             10171..10398
                     /locus_tag="LP468_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL2081227.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10550..11101
                     /gene="lepB"
                     /locus_tag="LP468_001690"
     CDS             10550..11101
                     /gene="lepB"
                     /locus_tag="LP468_001690"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2081228.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11184..11684)
                     /locus_tag="LP468_001691"
     CDS             complement(11184..11684)
                     /locus_tag="LP468_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2081229.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11963..12361)
                     /locus_tag="LP468_001692"
     CDS             complement(11963..12361)
                     /locus_tag="LP468_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2081230.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12621..13481
                     /gene="ylqF"
                     /locus_tag="LP468_001693"
     CDS             12621..13481
                     /gene="ylqF"
                     /locus_tag="LP468_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL2081231.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13474..14241
                     /locus_tag="LP468_001694"
     CDS             13474..14241
                     /locus_tag="LP468_001694"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL2081232.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14297..15154
                     /gene="dprA"
                     /locus_tag="LP468_001695"
     CDS             14297..15154
                     /gene="dprA"
                     /locus_tag="LP468_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL2081233.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15276..17354
                     /gene="topA"
                     /locus_tag="LP468_001696"
     CDS             15276..17354
                     /gene="topA"
                     /locus_tag="LP468_001696"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL2081234.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17323..18699
                     /gene="trmFO"
                     /locus_tag="LP468_001697"
     CDS             17323..18699
                     /gene="trmFO"
                     /locus_tag="LP468_001697"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL2081235.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18897..19802
                     /gene="xerC"
                     /locus_tag="LP468_001698"
     CDS             18897..19802
                     /gene="xerC"
                     /locus_tag="LP468_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL2081236.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19839..20387
                     /gene="hslV"
                     /locus_tag="LP468_001699"
     CDS             19839..20387
                     /gene="hslV"
                     /locus_tag="LP468_001699"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL2081237.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20401..21801
                     /gene="hslU"
                     /locus_tag="LP468_001700"
     CDS             20401..21801
                     /gene="hslU"
                     /locus_tag="LP468_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL2081238.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21819..22610
                     /gene="codY"
                     /locus_tag="LP468_001701"
     CDS             21819..22610
                     /gene="codY"
                     /locus_tag="LP468_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL2081239.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22692..23567
                     /locus_tag="LP468_001702"
     CDS             22692..23567
                     /locus_tag="LP468_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL2081240.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8193 a         4079 c         4983 g         6403 t
ORIGIN      
        1 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
       61 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
      121 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
      181 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
      241 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
      301 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
      361 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
      421 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
      481 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
      541 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
      601 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
      661 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
      721 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
      781 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
      841 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
      901 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
      961 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     1021 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     1081 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     1141 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     1201 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     1261 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     1321 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     1381 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     1441 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     1501 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     1561 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     1621 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     1681 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     1741 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     1801 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     1861 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     1921 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     1981 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     2041 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     2101 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     2161 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     2221 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     2281 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     2341 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     2401 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     2461 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     2521 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     2581 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     2641 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     2701 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     2761 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     2821 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     2881 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     2941 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     3001 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     3061 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     3121 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     3181 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     3241 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     3301 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     3361 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     3421 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     3481 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     3541 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     3601 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     3661 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     3721 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     3781 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     3841 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     3901 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     3961 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     4021 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     4081 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     4141 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     4201 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     4261 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     4321 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     4381 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     4441 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     4501 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
     4561 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
     4621 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
     4681 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
     4741 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
     4801 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
     4861 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
     4921 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
     4981 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
     5041 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
     5101 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
     5161 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
     5221 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
     5281 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
     5341 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
     5401 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
     5461 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
     5521 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
     5581 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
     5641 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
     5701 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
     5761 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
     5821 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
     5881 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
     5941 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
     6001 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
     6061 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
     6121 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
     6181 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
     6241 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
     6301 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
     6361 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
     6421 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
     6481 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
     6541 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
     6601 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
     6661 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
     6721 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
     6781 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
     6841 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
     6901 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
     6961 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
     7021 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
     7081 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
     7141 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
     7201 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
     7261 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
     7321 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
     7381 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
     7441 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
     7501 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
     7561 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
     7621 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
     7681 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
     7741 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
     7801 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
     7861 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
     7921 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
     7981 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
     8041 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
     8101 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
     8161 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
     8221 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
     8281 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
     8341 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
     8401 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
     8461 aacggtcaat tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
     8521 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
     8581 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
     8641 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
     8701 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
     8761 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
     8821 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
     8881 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
     8941 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
     9001 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
     9061 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
     9121 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
     9181 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
     9241 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
     9301 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
     9361 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
     9421 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
     9481 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
     9541 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
     9601 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
     9661 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
     9721 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
     9781 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
     9841 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
     9901 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
     9961 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    10021 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    10081 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    10141 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    10201 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    10261 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    10321 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    10381 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    10441 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    10501 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    10561 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    10621 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    10681 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    10741 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    10801 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    10861 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    10921 ctttacacta caagagctaa cgggacaatc caagcttccg gaagataatt attttgtact
    10981 tggagataat cgaagagttt caaaagatag tcgttcgttt ggcacgatca ataaaactga
    11041 tattctaggt aaagcaagat ttgtctatta tccacttgat gaaataaaat ggatccagtg
    11101 agaaacaata aagcgtgcag tctgttgaga ctgcacgctt tattgtttaa tccaaaatca
    11161 gtttactacc ttagtacgta aaatcaaaca gctcgtttaa acacttttct agcctctaaa
    11221 gttttgataa atgaataaac aaccattatt tgaataggga tttggatcat attcctgatg
    11281 aatctaccta gaaaaattac tttgaaatct gcaccaaaca aaacagacat cagccaagaa
    11341 ttgataaaaa ggctgactgg gatcataatc aataattggg cagcgatgac ggaaggcagg
    11401 tttatctttt tatgatataa aaataagcca ttaataaatc caccaaggaa agccgtgata
    11461 agaaaagcag cttgaaacgt tcctgaacca aatatcgtga aatttaaagt gttcgacaac
    11521 atttcaagca aaccagccca gatcggtcca tatagataac ccataagcgc catacttaaa
    11581 aatccgaatg tgatttgaaa ataagcagga ccaatcgcta tcttgtataa gatgacatca
    11641 agggctaata aaagagcaga ggtcgacaac aatcttgcat tcatttcggg caatctaaaa
    11701 acgtcttttg caatcaaagt gttcaaaata ttctctcctt tgtcagttaa taataaaagg
    11761 ataccataaa atcaccaatg tgtcatgaca cattggtgat ttacatacac tggcatctaa
    11821 caattaaaaa aagggtgaga agactgcttt tataaactgt aaaaaagaga ttgtacgaat
    11881 aaaaaaaata gaggcggaga atacttatcg tatcatccgc ctttgttttt ttgttataaa
    11941 aaacgtcaga ttagttatct gcttacatct tcatccatac gggttctaat gtatttccgt
    12001 ctagatcttg gacttctaat gaaaacattt cttcttcagg cattcccata tctacttcgt
    12061 ggaaagtacc accattttct tttgcaattt gagcaaattt ttttacttca tccgcatttt
    12121 caacactaaa cgaaatcaaa gcaccacttg tttttttatt atcagctatt tctttatctt
    12181 ttataaattt tttataaaaa tcatgagaga gaagcattat ccaaaaagtg tcatcccata
    12241 ccattgaacc agcttcttca gtagaaaatt cttcattttt tttaaaaccc agcttttcat
    12301 aaaaagcaac ggaacgattg acatcagcaa caggaaaatt aacaaaaacc atactattca
    12361 tttgtttcgt ctcctttctg ttttgttcgt ctatcatctc ttatttagga aacgctgtca
    12421 aaaatttaga ttcatatata gaaaccaaaa taaaaatttg catcatcaaa aaagtgaaga
    12481 tgtgatagaa tgaggactgg ttcactttca cttaactaat agatggaatt tctttataat
    12541 aaaaaagtga atttatattg aaaaagaaaa aaacaagtaa agccggggaa tattccggta
    12601 tgaaaggaat ggagagaaca atgaccatcc aatggtttcc gggacatatg gcaaaagccc
    12661 gacgagaagt ttctgaaaaa atgaaatatg tggacatcgt atttgaattg gtagacgcac
    12721 gattaccttt atcttctcgt aatccaatgc tagatcagat cattcagcaa aaacctcgcc
    12781 ttgttttatt gaataaagcg gatctggcag atccacaaca gacaaagctg tggcaagaat
    12841 attttcgtaa acaaggccat cttgcattag ctatcacggc acaagaaagt aaaggaatta
    12901 aaggtctagt acctgcggct aaagaagcat tgaaagaaaa acgggcaaga gatgctgctc
    12961 gggggatcaa gcctcgcgct attcgggcaa tggtcttagg tattccaaat gttgggaaat
    13021 ctacgttgat gaatcgacta gtaggcaaga aaattgcaca gacaggaaat aagcctggcg
    13081 taacaaaagg tcagcagtgg cttcgtttag gtaatgagtt ggaattgtta gacacaccag
    13141 ggattttatg gcccaaattt gaagatgaag aaatcggcaa aaaactagcg ctgacaggcg
    13201 cgatcaaaga ccagcttgtc catttagatg atttagcgat ttacggatta gacttttttg
    13261 cccgatatta ttcaggaaga atcagcgatc gttatggttt atcaatcgag caagaagaaa
    13321 aattggcacc ggaattactg atggatatta cagcaaaacg tgggtataaa gaagactatg
    13381 atcgtggcag cgaattagtc gtgcatgata ttcgtcaagg aaaacttgga cgatacacac
    13441 tggatcgttg cgaagaaatg gagcaaaaaa gtgatgactg aatccatcca aagtatcaaa
    13501 gaacgattga aaagcataca gagaatagat gatcctacac tagaatcatt aagaaatgat
    13561 ccacgcaaag gcgtgcagca agcactggct tcttttgaac gacgattgaa aaaggaagca
    13621 ttaattaagg aaaaatatga agaaatgttt tgctttgaaa agcaagggta cgcacaaggt
    13681 caccaatgga ttgccggcat tgatgaagta ggaagaggac cattagctgg acctgtcgtg
    13741 gcagctgcag ttatcttgcc gaaaaatgag atcatattag ggctgaatga ctccaaacaa
    13801 ttatcagaga aaaagcgaga acttctttat caacaagttc aagaaaaagc cctggcaatc
    13861 gggatcggga tcgttgatca gcagacaatc gatgatgtga atatttatga agcaagtaaa
    13921 ttagcgatga tccaagcagt agaaaaattg tccattgtac caagctattt gttgatcgat
    13981 gcgatgacct tggatttgcc tattcagcag gaaaaaataa tcaaagggga tgcacgatct
    14041 gtgtcgattg ctgctgcaag tatcattgct aaagtatatc gagaccaatt gatgaaagaa
    14101 tatgacgtgc tttatcctgg atatggtttc tcgcataatg caggttatgg aacaaaggaa
    14161 cacttagaag gacttgaacg acaaggaatt acgccaatcc atcgtaaaag ttttgcacct
    14221 gtaaaaaaat atttacaata aaaaacagcc gcttttacgt atcttattag aaagagagac
    14281 gaaaggcggt tttatgatgt atcaaataga agaaaattta ttgaaacttg cttatacaaa
    14341 aggaatcagt agtcaaggaa aatgggcact tgctaactgg atgatgcagt atccttataa
    14401 agaaatcgga tttgaagaca tcattaagat aggtaaaata accaaacacc gggagctgtt
    14461 tcgcaaaagt tggcaggaaa ttcacgctaa ctggggcaaa atccaatcga aacagtcgtt
    14521 tatcacttgc tttgatccca aatatccccc tcagctgctt cacttgacct atccgccaat
    14581 tgtactgttt tataatggtg atctatcttt actttcttgt aacatgttaa gcgttgttgg
    14641 tggaagacac acttctgctt tagccaaaaa aacagtttat tatttactaa aaccagtgat
    14701 agaagctgga tatgtgatcg tcagtggctg cgcgaaaggg atagatacat acggtcacca
    14761 agcagcaatc tctcatggtg gacggacaat cgcagtcatt ggaacaggga tagagcaagt
    14821 ctatcctgct gaaaatcgtg acttgcaaga ggtgattgca aatgatcatc ttcttttgag
    14881 tgaatatcct cctcaatccg gcccgaaaaa gcattgtttt ccaatgagaa atcggattat
    14941 cgcagctttg tctaaaggaa catgtgtctt tgaagccaag aaaaaaagcg gctctctgat
    15001 aacagcacag caagcattgg atcttggaag aacagttttt tctgttccag gaaatatttt
    15061 aacagaacat tctaccggat gtcatcattt gatccaagac ggtgcagttt gcacggtttc
    15121 gggtgaagat atcttggcag aatttaaaga ataacaccat acttttcatt tgcttttctt
    15181 gacaaacgtt ttctgaatgg atatgattag ctacgatttg tatgaatcct cttttaatag
    15241 taggaacacg acaatggaaa ggagtccatt cagtaatggc gtataaatat ttagtgattg
    15301 tagaatcacc tgcaaaagcc aagacaattg agaaatatct tggacgaaac tataaagtaa
    15361 tggccagtgt tggccatata agagatttac cgaaaagtaa aatgggtatc gattttgaaa
    15421 acaattatga accccattat atttctatac gcggaaaagg cgatgtcatc aaaagcctga
    15481 aagccgcagc aaaaaaagct caaaaagttt acttggcaag tgacccggat agagaaggag
    15541 aagcgattgc ttggcattta gcgtacctac ttgggttgga tctgaaagaa aaaaatcggg
    15601 tggtcttcaa tgaaatcaca aaagacgcag tcaaagcagc ttttaaggaa ccaagaacga
    15661 tcgatgtaga tttagtagat gcacagcaag ctcgtcgtac cttagacaga atcgttggtt
    15721 attcgatcag tcctattctc tggcgtaagg tcaagaaagg gttaagtgca ggacgtgtcc
    15781 aatctgtcgc tttaaaaatt attattgacc gtgaaaaaga gatccgagaa tttgttccag
    15841 aagaatattg gagcatcgac ggtaatttta aaaaagctcg caagaaattc aaagcaaatt
    15901 tctggggaat cgacggtaag aaaaagaaat taccagatgc acaaagtgta aaagaagtca
    15961 ctgctagaat tgatggaaca gacttcgaag ttaaaaaagt agaaaagaaa gagcgcaaaa
    16021 gaaaccctgc gaatcctttc actacaagta gcctgcaaca agaagctgcc cgtaagttaa
    16081 actttcgaac aagaaaaacc atgatggtag cacagcaatt atatgaagga atcactttgg
    16141 gtaaacaagg aacagtcggc ttgattacat acatgcgtac tgattctacc cggattgccg
    16201 atacagcaaa agcagaggcc gcagcattta ttgaagatac gtatggaaaa gaattttcta
    16261 gacatgatca ccgaaagatc aaaaatgctc aaggcgcaca agatgcccat gaagctgtgc
    16321 gtccaacgag tgtgcttcgt acaccagatg aactcaaaca atatttagat aaagatcaat
    16381 tgaaacttta tacattgatc tggtcacgtt ttgtggctag tcagatgaca ccagctattt
    16441 tagatacaat gaaagtgaca ttagaacaaa atggtgtcat cttcattgcg aacggttcaa
    16501 aaatcaaatt caaaggattc atgcaagtgt atgtggaagg tagagatgac ggcaaagaag
    16561 agaaagaaaa tattcttcca gaacttgaag aaggcgatgt agtccaatct gttgatattg
    16621 aaccaaaaca acattttact caaccaccag cacgttttag tgaggctacg ttgattcgtg
    16681 cactagaaga aaacggggta gggcgacctt ccacttatgc accaacactt gatacgatcc
    16741 aaagacgcta ctatgtaaaa ttgacacaaa aaagatttga gccgactgaa ctaggagaaa
    16801 ttgtcaattc attaatctgt gaattcttcc ctcaaatcgt cgatatccat ttcacagcag
    16861 aaatggaagg agatttggat aaaattgaag aaggcacgga agcgtgggtc aaagtggttg
    16921 atcgtttcta taaaccgttt gaaaaagaac tgacgaatgc ggaagaaaaa atcgaaaaaa
    16981 ttcaaatcaa agatgaacca gcaggattcg attgtgatgt ctgtggacat ccgatggtga
    17041 taaaattagg gaaatatggg aagttttatg cttgcagtaa ttttcctgat tgtcggaata
    17101 cgaaaccaat cgtaaaagaa atcggtgtga cttgcccagt atgtcatgaa ggacaagtca
    17161 ttgaacgaaa atctaagaaa aacagactat tctatggttg ttcccgtttc ccagaatgtg
    17221 aattcacttc ttgggataaa ccagtgggca gaaattgtcc aaaatgtgac ggatatctgg
    17281 tcgagaagaa agtcaaaggc ggtaaacaag tagtctgtgt aaatggagat tacgaagaag
    17341 acatccaaaa ataatagaaa agaggttctt tcattgaaaa tggtaaatgt tgttggagca
    17401 gggcttgccg gaagtgaagc tgcttggcag atcgcacaag caggagtccc tgtccgttta
    17461 tatgaaatgc gtccagtcaa atcgactgag gcgcatcaca caagtaattt tgctgaacta
    17521 gtatgttcca attcattaag aggaaacagt ttggctaatg cagtagggtt attgaaagaa
    17581 gaaatgcgcc gattgaattc ggtagtaatc acttcggcag atgaaacagc agtgccagct
    17641 ggtggtgcct tagctgttga ccgcgattct ttttctgaaa caattacccg aaaagtcaaa
    17701 gagcatccat tagtaacagt gataaacgaa gaaattactg aaataccgga aggaatcacc
    17761 gtagtagcaa caggaccttt gacttctcat ccattagcag aaagcatcaa agcattcaat
    17821 ggttcagatg gtttttattt ctatgatgca gctgcaccaa tcgtagacaa agctacgatc
    17881 gatatggata aagtatattt gaagtcccgc tatgacaaag gagaagcagc ttacttgaac
    17941 tgtccgatga cagaagagga attcaaagct ttccatgagg cactaatcaa tgccgaagtg
    18001 gcagaactta aatcttttga gaaagaaaaa tattttgaag gatgtatgcc aattgaagta
    18061 atggcacagc gaggattcaa aacgatgctt ttcggaccta tgaaaccagt tggattggaa
    18121 gatcctaaaa ctggcaaacg tccttatgct gttatccagc tgcgtcaaga caatgctgca
    18181 gcttctttat acaacatcgt gggctttcag actcacttga aatggggcga gcaaaaacgt
    18241 gttttccgga tgattcctgg gttagaaaat gctgaattcg ttcgctatgg tgtgatgcac
    18301 cgaaacagct ttatgaattc gccagaattg ctgaaaccga cttaccaatc aacgaaacgc
    18361 gaagatctgt tctttgcagg tcagatgact ggtgtagaag gctatgttga aagtgcagcg
    18421 agcggactac ttgctggaat caacgccgca cgcttagcaa aagaaatgga accagtcgag
    18481 tttccacaag aaacagctat tggaagtatg gcttactaca ttactcatgc ggaaggaaaa
    18541 catttccaac cgatgaatgc caactatggt ctgtttcctg aactgccaga gcgcattcga
    18601 gacaaaaaag caagatatga agcaattgca caacgagctt taaaagctaa tgaggcaata
    18661 aaaacagaat tagaaaaaac tgcaatccca aatgagtaag gaaactccat gaagagggtg
    18721 agacggatag tctcgctctt tttcttgcgt ttttcttaag aatttctcaa acaaaatgtg
    18781 aggaattgcg ccaattgtga acaaacttag aaatattggt taaattctga caatttattt
    18841 gtctttttat aaacgctgtg ctaaattatt ctctgggaca aaaggaaggt gagaaaatga
    18901 cagaagccac gtgggaacaa aaatttttgc gttatttgat tgtcgaaaga ggatattcag
    18961 aaaaaacgaa agaagcatat gaagaagaca ttctccattt caaacatttt ttggaggaat
    19021 ctggagacgc tgatctgctg aaggcggaat attttacggt tcgtgtctat ttgagtgcat
    19081 tagctgatca tcgtcctagc tatagcagaa attctatcag tcgcaagata gccagcctac
    19141 gttcgtttta tcagtatctt ctcaaagaag aagtgataaa agaaaatcca ttttcttacg
    19201 ttcatctcaa aaagaaaaat ttgagactgc cacgtttttt ttatgaaaat gaaatgcaag
    19261 cactttttga cagcgtagca ggagatagtc ctttggattt gaggaaccgc gctttactgg
    19321 aagtccttta cgggtcaggc atccgtttaa gtgagtgtag cagtttgtcg gtatcagaca
    19381 ttgattttga ttcagaggtc atgttgatcc atggtaaagg gaacaaagag agatatgctc
    19441 ctctaggttc ttttgctcaa gatgctctgc aagaatattt cagggaaggc cgccaggtat
    19501 tgatgacaaa atatcacgaa gagcatgata tcgtttttgt gaatcatcat ggaaaaccaa
    19561 tcacgcctac tggaattgaa tatgtcttga atcaaatgat caaaaaaagc agtttggata
    19621 gtgatatcca tcctcacatg ctgcgccata catttgctac tcatttatta aataatgggg
    19681 cagatttgcg gacagtccaa gaattgctag gacatgccaa tttatcgact acccagatct
    19741 atgcccatgt aacaaaagaa agtttacaaa aaaactatcg ttctttccat ccaagagcgt
    19801 aaaaataagg aaaagaacaa atttaggagg aaacaaacat ggtcgaatca ccatttcatt
    19861 caaccactat ctgtgccgtc gaaaaagacg ggaaatttgc tatggctgga gatggccaag
    19921 taacaatggg tgaatctgtt gtcatgaaag gcactgcaaa gaaagtacga cgtatctaca
    19981 atggagaagt tgttgtaggt ttcgccggaa gtgttgcaga tgcgtttact ttagaagaaa
    20041 aatttgaagg caaactaaac gaatataacg ggaatctaca acgcgcagct gtcgaattag
    20101 ctcaagaatg gcggacacag caatctatgc aaaaacttga agcgatgctg atcgtaatga
    20161 atgataaaga aatgcttctt gtttcaggta caggagaagt tatcacacca gatgatggta
    20221 tcttagctat cggatcagga gggaattttg cgttggctgc agcccgagca atgaaaaact
    20281 atgctcaaaa cgacatgagt gcgaaagaaa ttgcagaaaa tgcgttaaat attgccgcag
    20341 atatctgtat ctttactaat cataatatta tcgtagaaga actgtaagag gtgagtagat
    20401 atgtatgaat taaaacaaac accaagacaa atcgtaagtg aattagatga atatatcgta
    20461 ggacagcacg cagcaaaaaa atctgttgcc gttgctttgc gtaaccgcta tcgccgtttg
    20521 cagttagatg aaaaaatgca acaagatatt acaccaaaaa atatgctgat gatcggacct
    20581 acaggggtcg gtaaaacaga aatcgcacga cgtttggcaa aaatcgtcaa tgcaccattt
    20641 gtcaaagtcg aagcaacaaa atttactgaa gtcggttatg tcggaagaga tgtagaatca
    20701 atggttcggg atttagtaga aaatgcgatc caaatcgtag aaaaagagca gtacagccgt
    20761 gtatacacaa gtgctaaaaa aaatgcagaa aaacgtttgg taaaaatctt ggtacctggt
    20821 atcaaaaaag aacagaaaca atccactaat caatttgaac aaatgatgaa tctttttaat
    20881 gctagtcagc aaaataccgc tgaaccgcaa gaagaagtga cagaagatat tcgaatcaat
    20941 cgccgtacag tcttggaaca actacaaaag ggtttactgg atagtcgtga agtaaccatt
    21001 gaagttgaag accaaaagaa acctgcacca atgatgaaca atggattgga gcaaatgggg
    21061 atcgacctaa atgaaactct aggtgctttg acaccgaaga aaaaagtgga acggacggta
    21121 acagtcaaag aagctttaga gttattgatc aaggaagaat cagcaaaatt agtcaaggat
    21181 gctgatatcc atagtgaggc aatcaaatta gcggaagaaa gtggaattat ttttatcgat
    21241 gaaatcgata agatcacttc taaatcacag caatctggag aagtatccag agaaggcgtc
    21301 caaagagaca tattgccaat tgtcgaaggt tcacaagtaa acacaaaata cgggatcatc
    21361 caaacagatc acgtcctatt cattgcttca ggagctttcc atttgtctaa accaagtgat
    21421 ctaattccag aacttcaagg acgcttcccg atacgggtag aattagatga tttgacagct
    21481 gaagattttg tgaagattct gaccgaacca aataatgctt tagtaaaaca atacgtcgcg
    21541 ttgatcggta cagaaaatgt gtcagttacg tttacaaaag aagcaattga acggatcgct
    21601 caaatcgctt tcgatgtcaa ccgtgacaca gataatatcg gcgcacgcag actgcatacc
    21661 attttggaaa aactactaga agatctatta tttgaagcac cagatatgca aatgggagaa
    21721 ataacgatca cagaagcata tgtggatgac aaacttggct caattgcggc aaatgaagat
    21781 ttaagtcgct atattttata aaaaatcgga ggacgacaat gacagacttg ctaacgaaaa
    21841 cccgcaagat aaacacactt ttgcagcaaa agaatacttt tgacatgcaa gcagatttgc
    21901 cttacgataa aatggctgtc acactaggtg gtattcttga cagcaacacc tatatcatag
    21961 gaagtgacgg agtattacta ggttataatg aacgtcacga tgtgaacaat gaacgaatca
    22021 aaacaatgtt tgttgagaaa caatttcctg aatcttatac tgatacagtg gcacagttga
    22081 tgaaaactga agctaatatc ccaattacta gtgatattac tgcatttccg gtagagtcaa
    22141 gagagaaata tccatttggt ctgacgactg tcgttccgat ctttggagct ggcgaacgtt
    22201 tgggtacgat tatcttatct cgtatggaac aatcgtttgc agatgacgat ctagtcttag
    22261 cagaatatgg agctacggtt gtcggtatgc agatccttta tcagaagtct cgaagcatcg
    22321 aagcagatgt acggagtgca acggctgtcc aaatggcaat caacacatta tcttatagcg
    22381 aattgaaggc tgtacaagct atctttgaag cattggatgg agatgaaggt cgtctgactg
    22441 cttctaatat tgccgatagt atcggcatca ctcgttctgt gatcgtcaat gctttacgaa
    22501 aattggaatc agctggaatc attgaatctc gttcgttagg catgaaggga acttatttaa
    22561 aagtattgaa ttcccgtttt aaagacgagt tagcaaaaca cagttattag aagtaagggg
    22621 actggggcag atagaaatgt ttgttccagc cttcccattt taaaaagtaa gtcgaagttg
    22681 gaggaatggc aatgactgtt attattcaaa atgaccagct gatcgccgaa atcgctgaac
    22741 acggtgcgga attgatcagt ctgaaatcaa aagaacatgg tttagagtat atctggcaag
    22801 gtgatccagc gtattggggc agacatgcac cggttttatt cccttttgtt ggacgtttaa
    22861 aagatgatca gtatgtttat caagggaaaa catatcaaat ggggcaacac ggatttgctc
    22921 gggatatgga ttttgaagtc attgaacatg gacaagaaat ggctagtttc atcttaagga
    22981 gtacgccgga gacattagaa aagtatccat ttgattttga attagtgatc agctatgaat
    23041 taggaggaga cggcatcacg gttcattatc aagtggcaaa taccggtgaa aaagaaatgt
    23101 tcttttctat cggtggacat cctgctttca atgtacctct tgaagaagga ttgtcatttg
    23161 aagatttcta tctggcattt tctccattga aatcaagatt acgcctacca ttgaaaggcc
    23221 cattcatcga tatggatcaa aagacgttag gtcagacaaa tacgaatctg gctttgaatc
    23281 gtgaactttt tgagcaagat gccttggttt ttgaaacaag gggtctaaat gcgtacgcca
    23341 ttcgaagtga aaaatcttcc catagcgtaa ctttaagcta taaagatatg ccttatgtag
    23401 ggatctggtc tccttatcca aaagaagcgc ctttcgtttg tatcgaaccg tggtgcggaa
    23461 tcgctgacac ggtgaacagt agtggaaact tgatggaaaa agtagggatc aatcaactag
    23521 gtgcccatga aatcttcaag acaaaatatt ccatcacagt gaagtaagag gttgtgaccg
    23581 agaagttagc agggaacacc gtttaccaag gtgtgtaaaa aagctatcct gtaagtaata
    23641 agggagtgtg acatcgat
//
LOCUS       DAFEML010000037        23434 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFEML010000037
VERSION     DAFEML010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.037"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(10..2154)
                     /locus_tag="LP468_001703"
     CDS             complement(10..2154)
                     /locus_tag="LP468_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2081241.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2511..3884)
                     /locus_tag="LP468_001704"
     CDS             complement(2511..3884)
                     /locus_tag="LP468_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2081242.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPIMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="LP468_001705"
     CDS             complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="LP468_001705"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL2081243.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGSEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="LP468_001706"
     CDS             complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="LP468_001706"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL2081244.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5333..6346)
                     /locus_tag="LP468_001707"
     CDS             complement(5333..6346)
                     /locus_tag="LP468_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2081245.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6427..7029)
                     /locus_tag="LP468_001708"
     CDS             complement(6427..7029)
                     /locus_tag="LP468_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2081246.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITKYNPSAFFGTSLDLQLRRRGIETIVLSGVATTNGVYATALDAFQHGYHVVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7214..7915
                     /locus_tag="LP468_001709"
     CDS             7214..7915
                     /locus_tag="LP468_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081247.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7925..10636
                     /locus_tag="LP468_001710"
     CDS             7925..10636
                     /locus_tag="LP468_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081248.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEHNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWSYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11033..12661
                     /gene="treC"
                     /locus_tag="LP468_001711"
     CDS             11033..12661
                     /gene="treC"
                     /locus_tag="LP468_001711"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL2081249.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRITIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12721..13902)
                     /locus_tag="LP468_001712"
     CDS             complement(12721..13902)
                     /locus_tag="LP468_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2081250.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14154..15680
                     /locus_tag="LP468_001713"
     CDS             14154..15680
                     /locus_tag="LP468_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2081251.1"
                     /translation="MKRLIGILAMLVLAGMLTACGGASGKAEDSKEKLSVMTTFYPMY
                     DFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQK
                     TLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVAN
                     IRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLAL
                     EYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGV
                     SLEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNG
                     YFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGY
                     QTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGA
                     FRYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH
                     "
     gene            complement(15749..16477)
                     /locus_tag="LP468_001714"
     CDS             complement(15749..16477)
                     /locus_tag="LP468_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081252.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16490..17770)
                     /locus_tag="LP468_001715"
     CDS             complement(16490..17770)
                     /locus_tag="LP468_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2081253.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYAQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17911..18513)
                     /locus_tag="LP468_001716"
     CDS             complement(17911..18513)
                     /locus_tag="LP468_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2081254.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18759..18965
                     /locus_tag="LP468_001717"
     CDS             18759..18965
                     /locus_tag="LP468_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081255.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19278..19997
                     /locus_tag="LP468_001718"
     CDS             19278..19997
                     /locus_tag="LP468_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2081256.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20078..20761)
                     /locus_tag="LP468_001719"
     CDS             complement(20078..20761)
                     /locus_tag="LP468_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL2081257.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            20993..23179
                     /locus_tag="LP468_001720"
     CDS             20993..23179
                     /locus_tag="LP468_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL2081258.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7815 a         4208 c         4582 g         6829 t
ORIGIN      
        1 taatttattc tatttcttta aaggcagatc aagccagaat gatttgtcta aacttaacaa
       61 ggttagtaca ggaacagttg cagctttaac tgtacgagta gttgtttctg gtatctgtct
      121 tgccgtaaaa ttgttccaca aatcccagat tgaagcgaca cggaagatgg aagaagcgtt
      181 gttgacgcgt tttatcgttg aaaattctaa tcctgtgatt ggcacgccat ctgttgtcca
      241 tttgattggc acatcgaatc gcttagacat attgaggatt tcagcgtttg cttcttcagt
      301 tgttgctgct tcttttttcg gttcatcata ttttgtcagg tcgtacgctt cgatgatcgc
      361 gttcaatttt tgtgaatatt ggcgatctgt agcataacgt ccttccaaat atttggttgc
      421 ttctttgtag tcttttgttt ccgacttcca agttggtttg tagaaatcag gattgccagt
      481 cagtccattt ttgatcaagt cggcatagtc ttccaaactt tccttgtaag aaggatattt
      541 acggaattgt gcgcggattt ggtagctttg tccggaacta tcttgttcaa gtgtattgaa
      601 ggtcacgctg cttcctttat atgatccttt gataccaaaa aggttatgat ttggttcgct
      661 tgataataag ctgtttccag atccactttc aaggatagct tgagccatca tgactgatgc
      721 gtagattcct tctttttgcc cgatttcctg tgcatcatct gcaatctttt tcaagaactg
      781 atcagttgtt tggttttgac tgaaatggaa cgagccatct aatccatcta aaatagatga
      841 gccgcctgtc agcgaacctg aagcagcagg taaacctgct aagtttactc ggacagcaaa
      901 atcaggcgtg aaatctgaaa tagaagttac tcgaacttta tctcctggtt gaggcgcatg
      961 gataaattgt ccgttcccaa tatagatacc tacgtggtgg gtaacaccag aagaaggtcc
     1021 ccagaagacg agatcaccag gttgggcctg acttactgga atctgtgtac ctgcatattg
     1081 ctgttcgcct gtccagccac cgatataatg accggttgct ttcatatata cgtaataagt
     1141 caaaccagaa cagtcaaaag tatttggacc ttttgctccc catacatatg gttttccaag
     1201 atgcttgaat gcttctcgaa cgattgcttg ttggacattc gttgtatttg taggcaatac
     1261 agcatcaatt ggtgatttta caacaaaatc agaagaagca gaagatggat tctctatacc
     1321 gctttgattt gctgtatttg gacgagatga agcattgttc gttccgccat ttgatgaacc
     1381 attgtttgga tggtttggtt ctctctgagt atttccattg ttattcgatc cagatgggtt
     1441 tgtttgattc gaagaattcc cgctgttcga attattgtta ttattgtttg aattatttga
     1501 accattatta ttgttgttat tacccacatc tggtttgttt ggcgtttccg gatctggtgt
     1561 actagggact tcttcactag gatcagttgg tttctctgtt gaagtatccg gtacaggttc
     1621 aaattctgca gtaatagata aattgttcgt acctactgta aaggtctttg catcataatt
     1681 tacttctttg gcaccattaa cagcgactga agcaatttgt tcaccttcag ctggcgtaat
     1741 agtgtaagtt accttcgttt ccgctaataa accttctacc gttccacttt ccgtaatatc
     1801 caaaggttgc tgttcagggg aatccgctgt cgaagcagtc agttggatct taccaatcaa
     1861 agaaggagca attgtaaggg aatatgtctc ggctggcttt tcattttctg atggatcagc
     1921 cggatcaatt tcagttggct cggtcgatcc tgttgttgag ttagttgttc cagttgggtc
     1981 ttctgtaaaa gaatccgttg tttcactagt agctgagctg gatgtagtcg tatctgttgt
     2041 gactgtttga tcagctgttt gattatctac ggcaaatacg gtattggtcg acaaaacaga
     2101 cggagcaatc agccaagtag cagctagcaa acgtatcgtt tttttatttt tcataataaa
     2161 ctagtccttt tcctttcatt gattttctgt cttattcagc attcattaga cattttttgg
     2221 aacagataat cgtgtcgaaa agctttttct tttcataaat ctgtctgtgt attctaaata
     2281 aaacaatttg taaataagca acgagcattc attcgttttt cattgacgtt cattttattg
     2341 catagaccac ctttgtttgg ggataaacaa gtggggataa aaatggttat gcatatgtaa
     2401 attataccaa agtttggaaa gtatcacaaa aatttataaa aataatgatc ctaaaaagaa
     2461 aaagactgaa atatgtgata aacatctcat acttcagtct ttttcattaa ctattcataa
     2521 gacattaggt cttcatcaaa cccgctaacg agagtagtaa tcattgctac gactagacta
     2581 acagccagtc ctgctaagta ccagaaaaaa gtaccggaaa tgaatgcagg caatgtggtc
     2641 agactaccaa atacaaaagc gatcgctttc acttgggcaa atcccattac agctccacca
     2701 gcagctgcac caatgcaagc agcaacaaat ggttttttca atgggatcgc aattccgtaa
     2761 acagttggtt cggtcactcc cgcaagtaaa atcgaagcaa aagcagaacc ggagatcgaa
     2821 cgagtttttg aacgtttact tcgtagaaat acacctaaag ctgcaccagc cattccaaaa
     2881 ttggctgctc ctgtcaacgg aacgattcgg tcgaacccat aagcagagat attactgatc
     2941 atgatagggt ttacagccca ttggatacca aatattacca aaatattcca accaccagcg
     3001 atgattgcgc cgctgatcgg tccgttaata tccatcatcc aagtaattgc ggcagctaaa
     3061 ccttcgccaa ggtaaacacc cgcaggcccg aataccatta acgtcaaagg aaccgtgata
     3121 actaatgaaa gtaaaggtac aaatactaat tgcatatttt cgcgaatata ttttttgagg
     3181 aatttttcaa caaaagaata aaagaaaata cctaaaatcg ccggcatgac agtagacgta
     3241 tactgcatca gtactacagg aatccccaga aaatcagtag ctgctttgcc actgtctgaa
     3301 agtaaagagg tcagattcgg ttcaatcagt gctgcagcaa tgacagccgc aatatatcca
     3361 ttcactttaa acgttttggc ggcagaaaaa gcaagaaaga ttggcagaaa ataaaagacg
     3421 gcattcgacg cagcagacaa aatatgataa gttccgcttg tttcactaag ccagccaatc
     3481 gtagtcgcta aaacaaccag accttttaat ataccagaac cggcaaacag cggaatgatc
     3541 ggcgtaaaga tttccgatat caaaccaaat agtttttcga tcggatttag cttttcttta
     3601 ggagctgaat gatcgatttg acgcgttaat tccttgtaag caggagccaa tccctgatcc
     3661 atgattattt ctgcatatct atcgagtaaa atgaaatact taatggaagg gatttgctgt
     3721 tttaattttt ctgcattggc tactggctgt tttttcaatt tgatacgaag ccgagtcgca
     3781 catggaagga cagaatcaat attgtctttt cctcccaact gttcaatcag catatgaatc
     3841 tgctcggaca gtaccatctg ttcaggattc attgtcgttt ccattagaag accactccac
     3901 tcactaatat aatattggcg taaggtgtca tttcgcctgt acgaataaat gcatgacagt
     3961 tattcaactc ttttttcatt tcttcatgtg ggataaagct aatcggtgta tctggtaaca
     4021 ataatttgat tttttccaat atttccgggt tcattgtctt tatttcttcc gccaattcaa
     4081 tcgattgtac ctcaagttct tctaaaacgt tttctaaaac agataaaaag cttggaagac
     4141 cgtttgagac agccaaatct attttttcac taccaaaggg gacaggcatg cctgcatccc
     4201 cgatacttaa tttatcaaag tgccccattt gtgcgattac tcgtgaaata tctgaattga
     4261 ttacttttcc ttttttcatg tttgtttctt cctctcattg ttaattttag actgctgatt
     4321 gttctaaagc ttcgcggtaa gggatagaag gttgcgcacc ataagactgc acagcaacag
     4381 aagaggctag atttccataa aggatcgctt ctttcaagtt actaaggtct ggctgaagtg
     4441 tgctgcttaa tgcgccaata aatgtatcac ctgcggctgt tgtgtcaacg gcatccactt
     4501 taaaagcagg gacgataccg tgttcttttt ctgtatgata gaaagcgccg gcactgccta
     4561 gtgtaatgat tactgttcca atacctaatt catggagttt ttcggctgct gcgaccaaac
     4621 tgttatgatc tgtcactctg attcctgtaa tgatttctgt ttctgtttca tttggtataa
     4681 tgatatctgt tttttcaagt agttcagtag ggatcgtttc acgagctggt gcaggattca
     4741 ggatcgttgt ttttcctgcg tcttttgcaa tagaaaaagc taggatcgtc gcatctaagc
     4801 tactttcaaa ctgagcaata ataaagtcac tgtttgtaat cagttgcttg ttttttagga
     4861 cttcttgttc atggaaagca ttatttgcac ctgcatggat caagatacta ttttctcctg
     4921 ctgcgtctac cataatcatt gcttgtccgg ttgtggcgcc ttggatttca gctatcccag
     4981 atgtatcgat gttttctttt gtcagtagat ctaataactg ttgtccttcg ctgtcagccc
     5041 caacgcctcc aataaaagat gtccgtgcgc ctgaacgttt ggctgccact gcttgattgg
     5101 cacctttacc tccgccagcg tgaaaaatct catgcgcatg cattgtttcg cctggcttgg
     5161 gcatgttggt taaacgaagg gtagtgtcca tattaatact tccaattact gtaaccgtgt
     5221 tcattttaca aacctccaac tatctcattt attttgatgg gaaaaattat tttttaaaac
     5281 gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa agctatttca
     5341 agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct tcccattctt
     5401 tttctgggaa ttggatccga tctaacaata atttggcaga tgtttgtccc aattcgaaga
     5461 tcggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct atattatcat
     5521 agccaataat gctgtagtct tcaggaatgc tttttccaga ttcctctaat ccgcgatata
     5581 atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa tcaagaagtt
     5641 ctgctgtgat ttggtagcca ccttgttttg agaactgtgt aggtaagagg atcagttggt
     5701 cgtgagagat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga gcgtggacat
     5761 tttccggcgg attttcagga tagacaaggg cgatcgtttg atgacctaga ctaagcaagt
     5821 gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca ctaaatcctt
     5881 cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa ttttcgttga
     5941 ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct cgacgtgtga
     6001 gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat aatatcgtga
     6061 cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg aagaatggat
     6121 tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc atttgtctag
     6181 caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc tgaacagttt
     6241 tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg attgaaacgc
     6301 cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc atactcctat
     6361 ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa tcacgtgtgc
     6421 cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc gtactcgtgc
     6481 agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac gatcactgca
     6541 agcatcttca gcaagtacaa catgataccc atgttggaag gcatctaatg cagtagcata
     6601 tacaccgttt gttgtcgcta caccgcttaa aacgatagtt tcgattccac gccggcgaag
     6661 ttgaagatca agagaagtac caaaaaaggc acttggattg tattttgtga tagtcaacat
     6721 attgtttgta tctttcaagg aatccttcaa caacaagtca gtgaattctg ccggagcaga
     6781 caaagcagat attcctccag catctgtctg atgacttaga taagagaaag tagtgatgtc
     6841 tacattcact aaaactttca aggcagcggt acgtttcaat gtttttgcta acaaatcatt
     6901 gtttgtcaga atagattgtg cagtgtgtgg agagagtgta ccgttattta cgatcccttt
     6961 ttgcatgtcg atcgcgacaa aagcagtttt tgataaatca aaaatcatat tttcctttaa
     7021 atcattcatg atgttccttc tttcaaataa caatgttttt tatgtaagta aatcataaat
     7081 cgtttatttg tcaactaaat aaaggattcc tttctttagt ctagagaaat tcagtggtaa
     7141 aataaataag tatgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
     7201 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
     7261 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
     7321 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
     7381 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
     7441 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
     7501 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
     7561 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
     7621 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
     7681 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
     7741 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
     7801 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
     7861 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
     7921 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
     7981 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
     8041 aactgctgga cctgtcatgc aaaaaacgat ggaccactat gttggtacag caggactttc
     8101 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
     8161 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggtaaaaa
     8221 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
     8281 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
     8341 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
     8401 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
     8461 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
     8521 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
     8581 caaagcttac aaagataaaa tggaacacaa tcaagagaag gcagaaaagt atttacaaga
     8641 tcgccctgaa gaacgcttag aagagctgaa aaaatcggca aacgaagaat tagaaccagc
     8701 acagcaaaaa ataacagaag gcaaagcaca aatagcacag ggaagaacac agttagaaga
     8761 tgctaaaaaa caattagcgc aacagtcagc agctatccag cagcttcctg aagcgcaacg
     8821 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
     8881 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
     8941 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
     9001 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
     9061 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
     9121 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
     9181 aaaatatgca atctatgcaa gtctagcctc agggataggc attgttttag gaacgatatt
     9241 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
     9301 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
     9361 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
     9421 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
     9481 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
     9541 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
     9601 cgtgggattg aaagattctc taagttctgt ctcagctaaa caatttggac cgatcattga
     9661 ctatcaagca atcgttacat tggattcatc cactgaagat agtcgtcaaa aagcagcgga
     9721 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
     9781 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
     9841 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
     9901 aacaggaatc gctattacgc aaaaagcagc agaactattt gacttatcta caggagatca
     9961 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    10021 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    10081 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    10141 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    10201 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    10261 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    10321 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    10381 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    10441 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    10501 tccattagtg atcacatggt ggtcttatgt cttatcagca ggattaacta tcgtatttac
    10561 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    10621 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgt tttgagctaa taacgagggt
    10681 cagctgctaa ttgaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcgagcaa
    10741 aaggaatact caaataaaat tagctcctca tgttttacat ttgagaagac tgattgccgt
    10801 agataaaagc ttttgagcac catttataga agaaacaaga atattttgct attttaaaca
    10861 agaggataga caaatacatg tctgatctct tgttttttat tgggcaacag acctcttaga
    10921 atgtataaag ataaatttta caaacgcttt ctgttcagtt ataataataa atgataactt
    10981 gtatatataa gttgcggtag gtaataaatc agttgaatgg aggtaaatat ccatgacatt
    11041 taaagacaaa gtcatttacc aaatctatcc caaatcttac aaagacagta atggtgatgg
    11101 aattggagat ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc taggcatcga
    11161 catgatttgg ctaaacccta tttatccaag ccctcaaaaa gacaacggtt atgatatctc
    11221 tgattacaca gccatcgatc ctatctttgg tacgatggag gaattcgaac agctaatagc
    11281 cgaagcaaag aaataccgga tagaaatcat gctcgatatg gtgctgaatc acgtttcgac
    11341 agaacatgaa tggttcaaaa aagcactagc aggggaccag cattatcagg acttcttcat
    11401 tttaagagaa gagccaacgg attgggtatc aaaatttggt ggaagtgctt ggtcgccatt
    11461 tggagatacg gggaaatatt atttgcactt atatgatcgg acacaagctg acttgaactg
    11521 gcggaaccaa gcagtaagag aggaactatt caaagttgtt cgtttttgga tggaaaaagg
    11581 ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt aaagacgaac aattgaaaaa
    11641 taacaaagaa aatgatggca aacctgaata tacggacaaa ccaatcaccc atacgtatct
    11701 aaaagaattg aaccaagcaa cgtttgggac ggattccact atcatcacag tcggtgaaat
    11761 gagctctacg acgatcgaaa attgtatctt gtatacagaa cctagtagag aagaattatc
    11821 aatggtcttt aatttccatc atttgaaagt cgattatgaa aatgggaata aatggtctac
    11881 tcctccattt gattttgcag aattaaagcg actatttcat acatggggag aaaagatgag
    11941 tgagggtaac ggctggaatg ctctattttt taataatcat gatcagccac gtgcgctcaa
    12001 tcgatttgta gctatcgatc agtatcgaaa acaaggagca gagatgctag caaccatgat
    12061 ccatttgaac cgtgggacgc cctatattta tatgggagaa gaaatcggca tgatcgaccc
    12121 agactattca tcgatttccg actatattga cgtagaaagt ttgaatgctt ataagttact
    12181 ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga
    12241 taactctcga acacccatgc aatggtcaga cacagaacaa gcaggattta ctacagggaa
    12301 accttggtta aaagttggag gcaagctaga agagattaat gtagaaaaag aactatcttc
    12361 tgaagattct attttgtcct attacaagaa attgattcgg ctgagaaaaa catatccaat
    12421 cgttgcacaa ggagattatc atgcttatga agcaaatcat ccggaagttt atggctttct
    12481 tcgccaattt gaaggacagc agctgcttgt attaacaaat ttctatgata aagatacaag
    12541 gatcaccatc ccagaaggat tcacagaagc caatattctt atcgataatt attccgatac
    12601 tgttcttcat caaagtctgg agctaaaacc ataccaggca attgctttgc tgaaaaatta
    12661 aaacaaaaac acaaaacgtc gttcctacga gctattctcg taagatcgac gttttgtgtt
    12721 ttatttaaaa taatcttctt cagaaaatga agagttttca tactctcctt tatcgccata
    12781 aaatttattg tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta atttgactaa
    12841 cgtatagata ggaataccaa aaataacgcc cacaattccc attagatcac ccatgacaag
    12901 taaaacgatt aagatcgtaa tcggatggat ctgtaaacga tcacccatta ctcgaggaat
    12961 caccaagtca ccgtggagaa gttgtacggc aaaccagaca atgacaaatt tgacagccat
    13021 aaaagtagag tcttggaatg caatgatcaa acctggaaag aaggcgataa acggcccaat
    13081 atatggaatg atacataaca acccagcaga aatagctaaa acactagcaa attctaatcc
    13141 gatcagtaag aaacaaaccc agtagactgc tccaaggata aatgaagcaa tgatttgccc
    13201 ctttagaaat gaacccaatt gttgattagc aatctttgtc aaatttttaa aatctgtacg
    13261 aaatgctggt gggacaatcg ctaaaactga ctgataaaat ttttgaggat ctctcaaaag
    13321 aaaaaaagcg acaattggac cagtaaataa agtaataaaa atagctgtaa cagttgaaaa
    13381 aatgttgctg atccgttgtg cgccactttc ccaataattt ccaataaatc cagctatatc
    13441 agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt
    13501 ctctaaaaat tgtcggagac tctcttgaaa atcttgaaac aaatctggca aactactgat
    13561 caatgtcttt gcctgttctt caagaaaagg aacaagccat acgcttccaa gccccaataa
    13621 aaataaaata atcacataaa cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa
    13681 acgtttgatg actggttcca aaagataata caagatcagt gcaaacaata atgggggcaa
    13741 gatagtagcg ataatgattc cgacaggctt gaatataaac gagatctgat ggaaaaaata
    13801 aatgatcagc gcaagtaaga taactattcc taaaacatag taagaggttt ttcctcctaa
    13861 aaagcggatc aaacgattcg ttgtatctgt ttcttttttc actctttttc ctcctttatc
    13921 tataacttca ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa
    13981 aatatcgtca atcattcata taaactttct catcaattaa aataagaaaa cgcttgacag
    14041 ttcttttaac catatgataa attaaatcct gttgctaaaa cgtaactatt acgttttgta
    14101 aaaggcgaat cggaacattc aaatgaaaga agatgagaag aggagtgtca taaatgaaac
    14161 gattgatagg tatattggcc atgctggttt tagcaggtat gttaactgct tgcggcgggg
    14221 caagtgggaa agccgaggac agtaaagaaa aattgagcgt gatgacgacc ttttatccta
    14281 tgtatgattt tacaaaagca atcgtcgggg atgaaggaga agtagagtta ttgattccag
    14341 cagggactga ttcccacgat tatgaacctt ctgctaaaga catggcaaag atccaagata
    14401 cagatatctt tgtttataat gatgaaaaca tggaaacatg ggtccccgca atccaaaaaa
    14461 cattacaaga aggcaatgtc catacgataa aagcgacaga aggtatgctt ttacttccgg
    14521 gaagtgaaga aggacatgat catgaccatg aacacgggga agaaggccat acacatgagc
    14581 tagacccaca tgtatggcta gctccaagtt tagcaatcaa gcaggtagca aacatacgtg
    14641 atcagctgat tgaagcttac ccagaaaaac aggaagtatg gacaaaaaat gcagcagcct
    14701 ataccgagaa acttcaagca ctccatcagc tttatcaaga aacctttaag caagcaaaac
    14761 aaagatcttt tgtcacgcaa catgctgcat tcaactatct ggcattagaa tatggattga
    14821 atcaagtatc gattgctggt ctttcttcta gtgaagaacc gtctgcggcg agaattgctg
    14881 aactgaaaca ctttgttaaa gaacatggaa tcaactatat ttattttgaa gaaaacgcca
    14941 aagatagtat tgccagaacg ttagcaaacg aagcaggtgt atctttagaa gtattgaatc
    15001 ctttggaagg attgacgaat gaacaaatag aaaatggaga aaactatctt tctatcatgg
    15061 aagcaaacct cgaagcgttg aaaaaaacga cagagacaga aaacccgcta gaagatactt
    15121 tgacccccaa aaaagaaaag agcgtctaca acggttattt tgaagacgag gatgtacaag
    15181 atcgctctct ttcagattgg gcaggaactt ggcaaacagt agatacgtat gtagaagatg
    15241 ggacttttga tcctgttttt gaatataaag aaaaattgaa tcaggataag acagcacaag
    15301 aatataaaga atattatacg aagggctatc aaacagatat tgcttcaatc aagatcagtg
    15361 agaaagagat ggcatttacg tttaaggatg gaacaacgaa acgttcaaat tatcgttatg
    15421 tagggaaaga aatcttgacc tacgaggcag gaaaccgtgg cgtaaggtat ctattcgaag
    15481 cagaagataa ggaaagtggc gcttttagat atattcaatt cagtgatcac acgattgcac
    15541 cggctgactc cgaacatttt catttatatg caggaaatga aagtcaagaa gcattgctga
    15601 aagaaatgga gaattggcca acattttatc cagatacaat ggatggacgt gaaattgcac
    15661 aggaaatgct tttgcactga taggcaaaaa agaaccgaag ggtttggatc ggctagtcat
    15721 ttagtcggtc caaactattc ggttcttttt atgaaatcaa tttctttaat ccacggatag
    15781 aggctgggat ggtctcgccg tttgccaacg tgacttctct ggttttttta ttaatcgacc
    15841 gcacattttg tgtattgata acataggatt tatgacaacg gataaaattc cgatgcattt
    15901 tctcgatttc tttgatcttc tcatagaatt gtaattgggc atgagtcaaa tggacttcca
    15961 gtttatgtgg tgctcctagc gaagtagaaa aatattggat gtctttgatc ggtaaaaatt
    16021 tgatctcatc attaaactct attttgaaga tatctttttg gatctgggac atttgaaaat
    16081 cttcgaaaat tttgctcagg atatgctcga cattttcttt taaatcataa agatcttctt
    16141 tgacgatata atcagtcggt tcgatgttgc tttttaagat tttcatcgac atttccgtat
    16201 gggaagtcac atagattatt tttcctaagg gatctaattc acggatcaat ttaccgatcg
    16261 ctacaccatc catttcactg tcttctagtt cgatatctaa aaagtaaata ccaaaagaag
    16321 aagttctgat cttggctgca ttgagaagtt cttccggatc agaggtagaa atatggacat
    16381 aactgtctaa gttttcaatc atgattctat ttttgatcac cgttgataaa acttctaatt
    16441 gttttggatc gtcttcacaa atataaatgg gaatcatatc attactcctt tattttattt
    16501 gtatataaat cgtttgagaa aaacgctggt tttcaattga tgtttcaagg aaaagataag
    16561 gattggtctt tgtcaattca tccaagataa acaagccaag gccttcgttt tttggatttg
    16621 tttttgttga gaaccctttt tgtttcaact ggtttaacgg caatgtattt gttgttgtat
    16681 tgatcacacg aatcatcacg gaatgattct tcttgagtat ggtcaattcg atttttttct
    16741 tctttgcagc actagctcct tcaatcgcat tgtccaagat aataccaagc atacgtacaa
    16801 ggtttaccgt atgtttcgta tccagttcga ttggctcagg aaaatgaagc tggacgacca
    16861 accctttttc ctgtgccatc atgagtttta atgacagtaa actacggatc tcaggaactt
    16921 tcatattatc caacatactt agattggccg gaaaaaggtt catcatctgg cgtgtaggta
    16981 atatcgtttg agcataataa gaccgtaatc cttctaagtc gccttctgaa atatagctgt
    17041 gaagagaaaa aagcagattt tggtaatcat gtttgaattc tctcaagtct tgatagtttt
    17101 tttctagatc tttgatataa tcctgttgca tcctgacttg ttgctctaat aactgatcag
    17161 ctaatttctt attagagatt ttccaataat aaaccaagat gatcaggcca acacacagat
    17221 atagaatgaa aaaactcgta ttcaaagcta agacatcagg tgtttcacca gaaaaacggg
    17281 tataaaaaat aatgatatag tatgtaaata atatcaatgt cccgatcgta ccgatcatac
    17341 ggcggtccac agtgtgaaac caagtctcta acgatttttt aaaacaaaaa gctaataaag
    17401 cagataaaaa agcggataag gcaatgtgaa aatactgcaa tgaatctcct ggttcaataa
    17461 ccgaagattt caaaacaaaa aaatcgccga tgcttgttaa gtgatctcct aaaagcgacg
    17521 tcaataaccc aaaaggaagc gcgtaaacca attgttgacg cgaagtcgaa aagaagaaaa
    17581 aagtaagcat cagcattcct atagcaatta gagcagtaaa aatccctaaa atcgaataga
    17641 cccatccaat caaaatacaa gaaatcagaa tgactcccgc aaacagatat ttgtatcgga
    17701 tgtgatggtc aatcaataag atacaaattg tgtaaatcaa atattgcaac gctatggacc
    17761 ataaaaacat aaagtacagc tcccattgat ttttaccaaa ttatagcaca attagcgtat
    17821 tattttttta atttttcagg gattttgaat tcagaactca taccaaagca gcagccagat
    17881 acaaaaaagt cagataagtt agttaattgt ttaatgattg tttttttcat gaaagattcc
    17941 tccaaaattc atcaagtagt ttgtaatagg aagcaacgta gctatttcta aaacaatccc
    18001 aagtagcaaa taggtagaaa agtaagaagc tgagaaaaat aaagtaatga gagaaaaaat
    18061 tagaaacatg ctgatcgcct tctttaataa tgggggacgt ttctcgggtt caatgggatt
    18121 gattgctgta cctcttgatc catagcgaag cagtaacaaa aagcagctga ttaacaaaaa
    18181 gaccatcatt gggaaggaga tagtcaattg cagatgtttc atcaccaagg gaacgcccca
    18241 taaataaagt agtgtccaca gcagacaaac gaattcagag tcggaatgca atccataagc
    18301 atatctgcgg atgcatatat aagaaagaaa ggtgattcct gtttccgccc atgagcctgt
    18361 caccagagaa aagactagaa cgaccgctag ttttccaaga ttattcaata aaacttctaa
    18421 ggcaaatttt acttggacat acaccatatc ttcttccgat ttgtctccgc tgaataaggc
    18481 ttctaataat ttgttcacaa ctttatcttt catctcatac gtacctctac cacaaatttt
    18541 atgctaaaaa aaataaaaaa cgtcttttgt ttcataaaaa gtggttttga catcaaaacc
    18601 gtcatgattt cctaaaaaaa tcttcgtttt ccaagaacct taccaaaaaa agtgacagtt
    18661 ttgatacgaa aagtactttt tatgacaagt ttgtgctttt tcgagtgatt tatgttaaaa
    18721 aaattactga ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg
    18781 aagtcggcga aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa
    18841 tagaaaaaat ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca
    18901 atgataccgc tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag
    18961 aataaaaaca gataaaatgt tgagagcata aagaggttgt gagtctccgt ttagctctga
    19021 gttacaagga ataatgttaa aaaacagctt ttcatgtttt atgaatattg ccacttgtga
    19081 ccgaggtgtt ggcaggagaa tactgtttat ttgaaaaaag ggctgcgaca agacttttgt
    19141 cacagccttt attttcatga ataggagtta cttttggcta cttttagaga agtagctttt
    19201 aaggagcaga taaagtcaag gcttttattt ctataaatga agtagtaaaa tgaagaacag
    19261 attttattac aggaaggatg ccgataattg tgatcattgt tgcaggaacg atcggtgcag
    19321 ggaaaagcac actgactgaa atgcttgccc aagatttaga aacaaaacct ttttatgaga
    19381 acgtggaaga taatgaagta ttgccgctat tttattctaa tccagaaaag tatacttttt
    19441 tattacagat tttctttttg aacaaacgct ttttggcaat caaagatgct ttcagccatg
    19501 atgacaatgt actagaccgc tccatctacg aagatagtat gctgtttcat ttgaatgcag
    19561 atttagggcg tgtttctgaa gtagaagtaa agcagtatga aggtctttta gaaacgatgc
    19621 tgaaggagtt agaagaaatt tcgccacaaa agaaaccaga tctactggtt tatattcgtg
    19681 tatcttttga aactatgtta gcgagaatca aaaaaagagg ccgggaatat gaacagctag
    19741 aacaagatcc tgaactctat tcctactata aagaactcaa tcgacgatac gaagagtggt
    19801 atgaacagtt tgatatatgt cccaaaatag tgatcgatgg ggacaaatat gatttcgtag
    19861 ccgatccggc atgtggagaa caaatcgtac aagaaatcaa gatgcgggca aagaaaatga
    19921 cagaagaggc agatgcccag tcgatccgct acactacaaa taacccgaaa gcaaagggaa
    19981 tctttacaac taaataatat aaaaactaag caaattgctc actcgcagat atttctctgt
    20041 gagcagcatc ttgcttagtt tttttgattc attgagatca aatagtgaac cgattcgtat
    20101 gataaaattg ccataaatga aatgtctgag tgagggccat gatcaaaaat aaaatggaaa
    20161 cgatcaaaat cgaatgggcg ccaaacagat gatgacagaa aacaaggaca atagctcctg
    20221 cgataaaggc aagaacgaca cttagatagt ggaaaaatcg atcaaaatct gctttttctt
    20281 tagaaataca ataatcatat aagttcgttg ctaccccttt taaatttcca gttgtaaata
    20341 aattagtgta ggcacgcccg ttgattttat caaaagctac ccactggatc gatgcagtaa
    20401 aagcaatcaa aatcgttact aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga
    20461 aaaaaatcac tgcttcataa tatagaacaa acaagcgcca gaaatgtttt tctttttttc
    20521 taaaataatc aattagatac tttgttagaa gaatccctaa gaaaaagaaa agggtagaca
    20581 atactttttt accaacactt agccattctc cgtcaaatgc ttggatgatc gatagaatga
    20641 tattgccagt ttgagcagag gcaaaagcac catattggat ataagtataa ctgtccatgg
    20701 ctcctccgat aaatgtcagc aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca
    20761 tttttttcat caccttttat gaatattttt gtcttcctta tcttagcata aacgattgaa
    20821 aaaaaggaaa aattttcaga aaactaaaat catatcgctt cccattttca tttttagaaa
    20881 ggtctgttag tataaagaaa aaatagacaa cgaaacttta aataaccaac ttgaaataac
    20941 caacttgaaa taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga
    21001 aaaagaaatt ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct
    21061 tcaacaagtc tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga
    21121 agcacccgga cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt
    21181 ctttaaaatg atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat
    21241 cacatatgat atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca
    21301 aacaatctgt gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat
    21361 actaatgatc acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt
    21421 cagccagaga aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata
    21481 caatgaaatt tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc
    21541 aaaggatact gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct
    21601 ttatatattt gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa
    21661 tatgaacctt tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga
    21721 taagaatgca cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga
    21781 acaaaaaaga agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc
    21841 tttggagaat gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga
    21901 tgaatttcaa gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa
    21961 caggatcaag ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc
    22021 agagccagca tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt
    22081 aactaattat cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa
    22141 taaaaatgat cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga
    22201 agcctatttg ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac
    22261 atttattcaa aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca
    22321 aacgcagcag cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga
    22381 tagtccatat gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt
    22441 tcattggcaa acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg
    22501 gcagctgatg gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa
    22561 atatcaaaat atagccgttg cagattatat tttgtcgata agccccaatt taaaatcaaa
    22621 atctgcagaa atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat
    22681 ctattcgctt gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag
    22741 tgatcaagaa tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc
    22801 cttatcgcaa gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag
    22861 acaaggaaaa cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta
    22921 ccgaaatgtc tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga
    22981 aaagaaagta atcgacttta atgaaataaa agcagaacca gtgacgacga tagaagaaga
    23041 acgaagacta ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc
    23101 tcaaatgaaa aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg
    23161 tgtgaaaaaa ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag
    23221 aagaaggaat gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa
    23281 gaagctattt ctggaacacc gtttattcgg aaaaaggagg tgtgacaaga attttgtcac
    23341 acctccctta tttattttga aaatgagaat actattatca aaatagagaa tatatagaat
    23401 aattctcatt attcaaacgt aaataatcag ttat
//
LOCUS       DAFEML010000038        22949 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFEML010000038
VERSION     DAFEML010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.038"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(62..664)
                     /gene="nrdG"
                     /locus_tag="LP468_001721"
     CDS             complement(62..664)
                     /gene="nrdG"
                     /locus_tag="LP468_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL2081259.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(979..3168)
                     /gene="nrdD"
                     /locus_tag="LP468_001722"
     CDS             complement(979..3168)
                     /gene="nrdD"
                     /locus_tag="LP468_001722"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL2081260.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            3467..4261
                     /locus_tag="LP468_001723"
     CDS             3467..4261
                     /locus_tag="LP468_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081261.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            4251..6293
                     /locus_tag="LP468_001724"
     CDS             4251..6293
                     /locus_tag="LP468_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081262.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            6574..6723
                     /locus_tag="LP468_001725"
     CDS             6574..6723
                     /locus_tag="LP468_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL2081263.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            6734..8248
                     /gene="dltA"
                     /locus_tag="LP468_001726"
     CDS             6734..8248
                     /gene="dltA"
                     /locus_tag="LP468_001726"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL2081264.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            8245..9450
                     /gene="dltB"
                     /locus_tag="LP468_001727"
     CDS             8245..9450
                     /gene="dltB"
                     /locus_tag="LP468_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL2081265.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            9495..9728
                     /gene="dltC"
                     /locus_tag="LP468_001728"
     CDS             9495..9728
                     /gene="dltC"
                     /locus_tag="LP468_001728"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL2081266.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            9731..10999
                     /gene="dltD"
                     /locus_tag="LP468_001729"
     CDS             9731..10999
                     /gene="dltD"
                     /locus_tag="LP468_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL2081267.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            11140..12222
                     /locus_tag="LP468_001730"
     CDS             11140..12222
                     /locus_tag="LP468_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL2081268.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            12222..13025
                     /locus_tag="LP468_001731"
     CDS             12222..13025
                     /locus_tag="LP468_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2081269.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            13095..13835
                     /locus_tag="LP468_001732"
     CDS             13095..13835
                     /locus_tag="LP468_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2081270.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            13846..14850
                     /locus_tag="LP468_001733"
     CDS             13846..14850
                     /locus_tag="LP468_001733"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL2081271.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(14895..16739)
                     /locus_tag="LP468_001734"
     CDS             complement(14895..16739)
                     /locus_tag="LP468_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081272.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            16951..17469
                     /locus_tag="LP468_001735"
     CDS             16951..17469
                     /locus_tag="LP468_001735"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2081273.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            17597..18280
                     /locus_tag="LP468_001736"
     CDS             17597..18280
                     /locus_tag="LP468_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL2081274.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            18589..18662
                     /locus_tag="LP468_001737"
     tRNA            18589..18662
                     /locus_tag="LP468_001737"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18623..18625,aa:Arg,seq:tct)
     gene            18821..19180
                     /locus_tag="LP468_001738"
     CDS             18821..19180
                     /locus_tag="LP468_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL2081275.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            19303..20934
                     /locus_tag="LP468_001739"
     CDS             19303..20934
                     /locus_tag="LP468_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL2081276.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(20996..21637)
                     /locus_tag="LP468_001740"
     CDS             complement(20996..21637)
                     /locus_tag="LP468_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2081277.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    21823..21899
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            21919..22227
                     /gene="rplU"
                     /locus_tag="LP468_001741"
     CDS             21919..22227
                     /gene="rplU"
                     /locus_tag="LP468_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL2081278.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            22254..22598
                     /locus_tag="LP468_001742"
     CDS             22254..22598
                     /locus_tag="LP468_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL2081279.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTEEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            22611..22904
                     /gene="rpmA"
                     /locus_tag="LP468_001743"
     CDS             22611..22904
                     /gene="rpmA"
                     /locus_tag="LP468_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL2081280.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         7188 a         3862 c         4630 g         7269 t
ORIGIN      
        1 aaatataaaa acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt
       61 tttatatcaa gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt
      121 cccaaatcac aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc
      181 tacttccgcg aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa
      241 ggatatcgat ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa
      301 aggtatagcc tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc
      361 gtacgacttg cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc
      421 cttgcacgta atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg
      481 gtttgccata tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc
      541 agccactaac gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt
      601 agtcagcaat atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc
      661 tcataaaaaa acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac
      721 tcgaccacat aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta
      781 ttttgataga gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt
      841 gtcatagcct cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc
      901 caactaaacg aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag
      961 gacagctttt tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg
     1021 gccatgtacc atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac
     1081 atcacatgtt tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg
     1141 tttgaaatca ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag
     1201 atacccgatt ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg
     1261 gagcataggg tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt
     1321 ctcaaattcc aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt
     1381 tgtataatat tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg
     1441 gcagaaacgg tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata
     1501 ttcatccccc catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc
     1561 ttttgcttct gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa
     1621 tccaatgtag cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc
     1681 ggtacgtgaa agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg
     1741 aatggcttct ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg
     1801 gtcagacagt aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg
     1861 caaattcaat gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc
     1921 gtctttccac ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa
     1981 ttcaacgatt ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa
     2041 tgctagttgt ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa
     2101 agtgaagatc agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg
     2161 aatctgtaaa attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc
     2221 taatgaagtg aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa
     2281 actttgcata gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg
     2341 ttctggcgaa tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc
     2401 aaaaggagca agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc
     2461 tacattggca ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc
     2521 gacttcggca ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca
     2581 gcaattcgtc atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt
     2641 ttgatgcgca tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat
     2701 cccggctgtc agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt
     2761 cacgacagtt tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt
     2821 actgcgagca aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc
     2881 gtttttttct agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc
     2941 agcaaaccgg cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata
     3001 agtaagtggt gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat
     3061 cttttgttca tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt
     3121 ctctggctgc tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc
     3181 ctgctaaatt gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg
     3241 ctatatatag tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt
     3301 ttattgtgaa aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt
     3361 tgctgaataa aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca
     3421 taagagcaaa ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag
     3481 aggaggagaa gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag
     3541 caaactttct cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt
     3601 tgttgggatt atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac
     3661 gatcaatttg cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa
     3721 aaacagtgag ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa
     3781 tttgatcgat accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat
     3841 gactaaagag gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga
     3901 actgctcaaa cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc
     3961 tagagcactt gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga
     4021 ctcgaagtcg gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc
     4081 aacgatactg ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt
     4141 tattaaagat ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt
     4201 tgagaaagta atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata
     4261 aactagccgt taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt
     4321 tgactttatc cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag
     4381 tcagaagagc aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca
     4441 ttactgttgt tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc
     4501 aaaaggaaat aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat
     4561 atgtgttaga aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta
     4621 ttattttttc caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta
     4681 gtccattttt tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc
     4741 ttttagcagt atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt
     4801 ttggagaaaa agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac
     4861 tcgcagtcat cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg
     4921 aaatcacttc atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt
     4981 ttttaatttt tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt
     5041 tatttttgat catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa
     5101 tgggtaacac gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca
     5161 ttctcggaat ttctttaatg acaattggcg gcacggctag tatctctact attttatcct
     5221 accaggagaa agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa
     5281 tcaagccgat tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata
     5341 aagtcattgg gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc
     5401 tgatcacgga aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt
     5461 ctttgaaatc acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata
     5521 tttcattata tggatctagt attggactgc cagataatca agaattgaag attcaacaaa
     5581 tgcttccaag tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag
     5641 atgataccgt ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat
     5701 caggtggaaa taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc
     5761 tcaatgctgt ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca
     5821 caaagaaact tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt
     5881 tgaatttctc ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata
     5941 tttttgtcac actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag
     6001 tccggcaatt agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg
     6061 ggattccaca aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc
     6121 cacccatgat attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata
     6181 taaaaactgc cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc
     6241 ttttgcttta tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg
     6301 aataagacaa gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt
     6361 tgtgacacga tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat
     6421 tataaagaaa aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg
     6481 ttagtaaaaa aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac
     6541 actttgtgtg aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa
     6601 ttgaattatt ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc
     6661 ctgatttatc tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt
     6721 taggaggaag agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa
     6781 tgaacctgat cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca
     6841 agcatcagac gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt
     6901 cgtttttggc aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg
     6961 ccatgcctat ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg
     7021 ggtggctaaa ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt
     7081 tcctgtcata acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc
     7141 cagaaatagc gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg
     7201 agaaccaaaa ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat
     7261 ggaagacttt gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga
     7321 tttatcggta ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa
     7381 taaagcagtt gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa
     7441 tgtgtgggtt tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg
     7501 agaaaatgtg ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac
     7561 tgcagaaagt ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac
     7621 agaagcaact gtagctattt caagtattca gattgaccag catgtactag atagttatga
     7681 ccgactaccg attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa
     7741 acctgtttca aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg
     7801 ttacctgaac aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag
     7861 ttaccataca ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg
     7921 tatggatcag caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta
     7981 tctgctccaa gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa
     8041 agtacagcag ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca
     8101 gttgactaaa tctatcaaag aacaattact agaagttgta atggattata tgattcctca
     8161 gaagttccat tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa
     8221 attaacagct gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg
     8281 ttttattttt ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg
     8341 gaaaaaagat taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt
     8401 ggaggtaatt attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata
     8461 cttgtatggg gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc
     8521 gccgttattt tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat
     8581 ggaaaagcat cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa
     8641 atgatcatgg aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag
     8701 tttctgctgt tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa
     8761 aaagatcagc tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc
     8821 caaaatattt ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta
     8881 ctgcttcctg tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta
     8941 ggttatatgt acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt
     9001 gcagtcggta caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt
     9061 ttatcatgga atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc
     9121 cgtgattatg tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc
     9181 aagatcgtaa tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat
     9241 ggattgacgt ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca
     9301 gatgcatgga tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg
     9361 catggcttag ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca
     9421 ggatttttag ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa
     9481 aggagaaaag gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag
     9541 atgaagtaag aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag
     9601 catctgttca attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg
     9661 aattcgagcg agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga
     9721 agggttgagt atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg
     9781 cttactgttt gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat
     9841 tagacgtgcc tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta
     9901 tgcattatct gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag
     9961 tccatttcat ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct
    10021 gggagcaccc gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc
    10081 tatgaaaaac aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt
    10141 aaaaactgat tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc
    10201 aatgaagaaa gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa
    10261 agtaaaagag aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc
    10321 tttacctgaa tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga
    10381 agtattcagc aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg
    10441 attaccaaaa caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg
    10501 agaaacgacg aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc
    10561 ccacgagcca gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt
    10621 ttctgatttt cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat
    10681 catcccaccg gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca
    10741 aggatttgcc aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga
    10801 ttttgtcaat caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa
    10861 aggctggttg gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc
    10921 tagtaagtat catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga
    10981 taaactacaa ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt
    11041 gaatattctg aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg
    11101 gtataatcac aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag
    11161 ctacttattg atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa
    11221 gtattcagag aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt
    11281 gtgattgcca aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac
    11341 gaagttggtt ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt
    11401 ggaggttggt gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg
    11461 aaaatcgtcc acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga
    11521 aataaacctt atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa
    11581 gccaaagagt ggggcatacg tcctggagat atggtcactc catatattga atacaaacga
    11641 atgaatggca gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt
    11701 tctctgcgag tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga
    11761 agcgatgtgc aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat
    11821 cccgatattg cttttgcttt agatactggt acagcaggag acactccagg aatgacacca
    11881 aaagaagcag attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg
    11941 atcccgcata aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca
    12001 ttccaatata cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga
    12061 gatggtgttc cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca
    12121 gtgattcatg aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg
    12181 cttgatagtg aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta
    12241 tttctgaata tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt
    12301 ggcttgtttt cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca
    12361 gtccttttcc ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac
    12421 ttttattcgc attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca
    12481 gaccaaaaag taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg
    12541 gcatcaattt gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca
    12601 tgtttttaat cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac
    12661 ctacgggtgt catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga
    12721 tgatttttgt ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat
    12781 ggacaaagtt cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt
    12841 tattgaaaga tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt
    12901 tgctaggagc aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt
    12961 cagttgcaga attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta
    13021 cttagcatgt aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg
    13081 agggggaatg tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa
    13141 atcaagggac aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag
    13201 gtagtgctac gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga
    13261 tccttagcca ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc
    13321 aacttcatcc taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt
    13381 ccattcactt tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag
    13441 ctgaagaatt aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag
    13501 tatgttacgc catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg
    13561 attcaggtta tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag
    13621 atacctatct ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg
    13681 gagaacttgc gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg
    13741 gtgatttaga acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag
    13801 aacttgctgc agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca
    13861 aatgaaaacc acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg
    13921 cctttagatg aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga
    13981 aaccaaaata cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt
    14041 gtccgtcgct taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt
    14101 tttatcatgc ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc
    14161 atccaagcac ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta
    14221 gtcattgatg gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt
    14281 gctcatggaa caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta
    14341 aaaaaagaca aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc
    14401 aaaccatttc ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc
    14461 ttgttgaaaa ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat
    14521 gaagattgga aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat
    14581 tacgggaagt ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt
    14641 gaagtccatt tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc
    14701 ttcggactag gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa
    14761 gcatctctat caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa
    14821 ccagaagaat tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg
    14881 gattccgcta ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga
    14941 tcaatgaaag tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc
    15001 atcatcatta agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat
    15061 aggtttgtat cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg
    15121 tgtatcgaca aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag
    15181 gaatgctcta aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct
    15241 tcgggaagat ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa
    15301 cgcgctaaga taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt
    15361 tttgcttctt ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt
    15421 aaatcttgca gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg
    15481 atatgctgtc gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa
    15541 tctacttgtc tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata
    15601 ataacgatta gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata
    15661 cctaatgccg tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt
    15721 gtacaagcta cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg
    15781 actaaagtgc ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca
    15841 ggagtaaaag ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa
    15901 attccgtacc attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct
    15961 gacgttaaga taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata
    16021 ccacttaaaa tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag
    16081 agaataagtg agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag
    16141 gtccctatag cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa
    16201 taaataaaac taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca
    16261 tagttctgat aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt
    16321 aaatctatca cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg
    16381 tataaaatct tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa
    16441 tttgcttcgt ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc
    16501 acggtaggaa tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta
    16561 tagaaaaccc acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata
    16621 aaataaaaga aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc
    16681 cactttatac gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata
    16741 aaggtattcc tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaac
    16801 tatttataat aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta
    16861 aagggaaaca tttttacagc tataatttga aaaaaattta tcgttattat atgattaaga
    16921 aggattgaat aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat aacttttata
    16981 agttctataa cgttgattat atttttaatt cttattcttc tcgtcgtctt ggttccccga
    17041 atttttggtt tgactcctta tattattgag gacaaagaaa tgagtccata ttatgcacaa
    17101 ggaaatctga tatatgtacg accgaaaaat acaaatgaga ttttagtcgg agatattatt
    17161 acatattatg aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac
    17221 aaccacgaag atttttatac aaaagctgat acaaagactt atattgagcc tggagtagta
    17281 aaaaagagaa atattatcgg tagtcccatc tttcagattc catatattgg actagtcctt
    17341 tcaaaaacgg catttgcatg gattcagggg ttattcttta cgattgcttt ttgcctaaca
    17401 ggaatcacag catggaatac ctttgtagag ttgaaaaaga agcggagacg aacacagaaa
    17461 tttttgtaag aatgttaaaa acataaatgt attccagaga tccaacgact cttctgaaca
    17521 tgaaacacga gaaaacactc atgcagcttg tagatttagt cagttgttcg tataatgtgt
    17581 gaagaggagg agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca aagaagaact
    17641 attggatttt atgcgtaccc agcaaaaaaa attaccgggt gagctaggca aactggaaga
    17701 agaagctcat gtagcagaag taccagttat tccccatgaa acagttgtat ttttgaaatt
    17761 tttacttgga cagcttcagc ctgaacgaat cttggagatc ggagcagcta tcggtttttc
    17821 atcaagtgtc atggccacga caatcggaga aaacgctcat gttacgacaa ttgatcgttt
    17881 cgatgtcatg atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt
    17941 gactttgctt gaaggtcaag cagcagatat cttgccggag ttgtctggtc cgtatgactt
    18001 tatttttatg gatagtgcaa aatcaaaata tattgaattt ttacctgaat gcttacgttt
    18061 gttaagaaaa ggtggcgttt tgatggtaga tgacatcttc caaggaggaa cgatcttgct
    18121 cccagatgaa gagattcccc gtggcaaacg agctatccat cgtaaattaa atgaatttct
    18181 tcgtgttgtg atggatcatc ccgatttgac atcgacaatc ttgccattag gtgatggtgt
    18241 gatcttaatg acaaaggaat cagaaacaat cgagttgtga tacatgatta tggcagcctg
    18301 tagataatcg attgaatcga gggctcaatt cgaacttgat gtaaaagttt ctatatttgt
    18361 aagtcaatta aaggatacag gaaatctaaa taaacaggag tagcatgaag tcaatgtagc
    18421 tcctgttttc aattgataac cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt
    18481 gatttagtag ttgggccaaa ataattcatt atttgctaat taaataacta tttcgtattg
    18541 acagaagcaa tttaattatc tataattatt gatgttccgc tgattcttgt catagtagct
    18601 cagctggata gagcatccgc cttctaagcg gacggtcggg ggttcgaatc cctcctgtga
    18661 cgctaaaaaa ccgttagaaa ctgaggtttc taacggtttt tctttgtttt ttgtgccaat
    18721 attgtttgtt ttcaaaggca aataaaataa aaaaacatcc ttatcgagta caattataag
    18781 gagcaaaaaa ataaaactca tcagaaaaga ggaagaagat atgacgatat tatctagaat
    18841 tttagtgact ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa cggtgagaac
    18901 tgattctgac acgacaagta gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc
    18961 tgttcaaaca ttgtttaaga accaaggagt gtacaatgga ctattaggag tgggactact
    19021 ttatggagct tatctttctt ccgcatctaa agaaatcaca agtatgctat taatatctat
    19081 tttttttgtt gcattatatg gcagtttgac tagcgatcgt tggattttac tcaaacaagg
    19141 tgggctagct ctgttggcat tgctttctat tttcttataa atatagaaaa aataagaatt
    19201 tatctaacag gaaactttgt gaaaaatatt actttatctc atgaaatatg atattctaat
    19261 gaatggtatt ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt
    19321 tcctcactaa aaaaagaatt ttcaggttat gatctttcaa gatttcagaa agatcttttg
    19381 gctgggatca cagtagctgc tgtagcattg cctttagcct tggcttttgg ggtatcaagc
    19441 ggagctgatg cggccgcagg tttgattacg gctatcattg ccggtatcgt tattggcggt
    19501 ttatcaggcg gtttttatca aatatcaggt ccgacaggtg cgatggcagc tatcttgatg
    19561 tctattgcgg caacaaaggg aatgcaaggt gtattgcttg ctactttttt agcgggtcta
    19621 tttttacttg cagcaggact tttccgatta ggaacactga cttcttttat cccagcaccc
    19681 gtaattacgg ggtttacttc aggtattgct atcattattg cattaggtca gatcgataat
    19741 ttatttggtg ttcactcgga aggtacaaac gttattgaaa aactaagtag ttatcaaacg
    19801 ataggatttc cgataaacac agcctctttg atcatgggag ggctagtcat tttagggatg
    19861 tttatctatc caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc tatcattttg
    19921 gcaacagcag ttatgctatt gttccattta ccagtagcaa ctgtgggtaa gattccacaa
    19981 acattgatca gtagtaatcg tttgaatatg ggagatttta gcttttctgc cttgcaacaa
    20041 gtggcagttc cagctattag cattgcttta ttaggaatga ttgaaagctt gctatgtggt
    20101 gcttcggctg gccgaatggc aaataagccc ttagatagca atcaagaatt aatggcgcaa
    20161 ggaattggaa atctgttgct tcctttcttt ggcgggattc ctgctactgc ggccatcgcc
    20221 cgtacaagcg tggccatcaa atctggtgca caaactagat tagctggtat gatacatgca
    20281 gttgtcttac tgctctccat gcttgttttt gcgccagtga tgtcacagat tccaatgcca
    20341 gcacttgcag gtgttttgat tgtgacggct tggcgtatga atgaatggga aacgatcaag
    20401 gagctattta ctaataaata ttggtcagca gttctattgt ttatccttac gatgatttgt
    20461 acagttatct ttgatttaag tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt
    20521 tttgttgtca aaagcgctgc tatcacgatt tcattagaaa cgatcgattg gcaaagaatg
    20581 gggctgccag aaacggaaaa gctgaataac tggacagtag tgtatattag tggtccactg
    20641 ttttttatgt cttcagaaaa actcaaaaat aaattggaag aactaaatca tcacgatggt
    20701 gtcattttct ccatgcgagg cgtaccaagt attgatttga cggcacgtgc agtttttgat
    20761 gaatttcaag aaaaagcaga gcaaagagga caaacgatta tctatacttc cttgcagcca
    20821 gaagtagaaa aacaactttc tcacttgtgg gaacatacat tcacgcatca acatcaaaca
    20881 gttgctcatg cgttgacagc tttacatgcg aaatatactg caattagcca ttaaaacaat
    20941 gaaaaagaac agacaagact gtaaactgaa gattttatgg tcttgtctgt tctttttaat
    21001 attgctgtaa aagtgaagct agtacttgcc agtcttgatg gataacaggt acaagggagc
    21061 gattgtagaa aatagctgct ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc
    21121 attcgtaggc atccttttgt tctgttaatt gtaagacagg ccctgtatag agttgaccat
    21181 gatttttggt aaccgtatat tctttgccaa gtaaacgttg aagaccaatg tttccaagtg
    21241 tcgcaattaa ttttggctgg accttcatca gttcgtaatc caatattggt gcatgcgcaa
    21301 atacttcgga acgagtaggt gtccgatttg gataaacagt ttctgactgt tgtgtccgtt
    21361 tattgatccg atgagtcacg cgatacgggc ggctccttac agcactggtg atatacacct
    21421 cttctcgtgt taagccagtt gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc
    21481 taaaaggaac atgcgtatca atctctgttt tccctggggc ttctcccacg agcatcagtt
    21541 taggatgaag aggtccttgc ccagcgataa atccttctac aggacggccg ttcattctta
    21601 aagaagcttc ttgtatcagt tcttttgggt attccattta tgctcctcct ttttctttta
    21661 ttataagaat aaaagaaaca caatgcgact attttatttg gtagaactgt gaggatagaa
    21721 aagcagaagt attgcttgaa tttttgtttt actttttgat tttaaattta gttgactaac
    21781 ggttgctgtt ctggtaagct agtactgttg taattgtgga ctccacagct acaaccgctc
    21841 agaacaagta ataagcacag catatgctgt cacttcggat ggcgagtcta agtatatcag
    21901 aaggaggtgc tttatagcat gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt
    21961 gaagtgggac aagcaatcta tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt
    22021 tttgacgaag ttatcttagt aggcggagaa tctacaaaag taggcgctcc aactgttgca
    22081 ggtgcaactg ttgaaggtac tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc
    22141 aaatacaaac ctaaaaaaca ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa
    22201 gtggttatcg acgcgatcaa cgcttaatag cgtttgagaa agaaggccta tatatgatca
    22261 aaggaacatt taagcgaaat gacgcaggtc agatcgtttc attcactttg accgggcatg
    22321 ctgatgctgg tccttatgga agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca
    22381 gcactgtcaa cgggattgcc tcattagccg gttttgagcc gattgttgaa atgaatgaag
    22441 aagaaggcgg ttatctttat accgaagtca cttcaggaat gacagaagaa caaaacaata
    22501 ttgctgagat tctattagaa aatcttttat taggattaca atcgatagaa gctgaaaact
    22561 cagaatatat ccaaattaaa acaattaatg ataaatagga ggtgcagacc atgttgttat
    22621 ctatgaatct acaattattt gcccacaaaa aaggtggcgg ttctacatct aacggccgtg
    22681 actcagaatc aaaacgtcta ggtgctaaac gtgctgatgg acaaacagtt acaggtggat
    22741 caattcttta ccgtcaacgc ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg
    22801 gagacgacac tttatttgca aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta
    22861 acaaaaaaca agtgtctgtt tatccagtag ctcaagaagc ttaattgaat cttatgatta
    22921 aagaggttgt gacaagactt ttgtcacag
//
LOCUS       DAFEML010000039        21643 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFEML010000039
VERSION     DAFEML010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.039"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            144..542
                     /locus_tag="LP468_001744"
     CDS             144..542
                     /locus_tag="LP468_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2081281.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="LP468_001745"
     CDS             526..1221
                     /locus_tag="LP468_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL2081282.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1805..2692)
                     /locus_tag="LP468_001746"
     CDS             complement(1805..2692)
                     /locus_tag="LP468_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2081283.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2877..3716
                     /locus_tag="LP468_001747"
     CDS             2877..3716
                     /locus_tag="LP468_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2081284.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3912..4886
                     /gene="sgrA"
                     /locus_tag="LP468_001748"
     CDS             3912..4886
                     /gene="sgrA"
                     /locus_tag="LP468_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL2081285.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5184..5540
                     /locus_tag="LP468_001749"
     CDS             5184..5540
                     /locus_tag="LP468_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081286.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5543..6700
                     /locus_tag="LP468_001750"
     CDS             5543..6700
                     /locus_tag="LP468_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081287.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6726..7166)
                     /locus_tag="LP468_001751"
     CDS             complement(6726..7166)
                     /locus_tag="LP468_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2081288.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7326..7832
                     /locus_tag="LP468_001752"
     CDS             7326..7832
                     /locus_tag="LP468_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2081289.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8000..9913
                     /locus_tag="LP468_001753"
     CDS             8000..9913
                     /locus_tag="LP468_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL2081290.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9918..10919
                     /locus_tag="LP468_001754"
     CDS             9918..10919
                     /locus_tag="LP468_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2081291.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11121..11327)
                     /locus_tag="LP468_001755"
     CDS             complement(11121..11327)
                     /locus_tag="LP468_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL2081292.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11973..12821)
                     /locus_tag="LP468_001756"
     CDS             complement(11973..12821)
                     /locus_tag="LP468_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2081293.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12820..13887
                     /gene="gnd"
                     /locus_tag="LP468_001757"
     CDS             12820..13887
                     /gene="gnd"
                     /locus_tag="LP468_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL2081294.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13889..14890
                     /locus_tag="LP468_001758"
     CDS             13889..14890
                     /locus_tag="LP468_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL2081295.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14887..15171
                     /locus_tag="LP468_001759"
     CDS             14887..15171
                     /locus_tag="LP468_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL2081296.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15204..16001
                     /locus_tag="LP468_001760"
     CDS             15204..16001
                     /locus_tag="LP468_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2081297.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16015..16848
                     /locus_tag="LP468_001761"
     CDS             16015..16848
                     /locus_tag="LP468_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081298.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16866..17723
                     /locus_tag="LP468_001762"
     CDS             16866..17723
                     /locus_tag="LP468_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081299.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17745..18254
                     /locus_tag="LP468_001763"
     CDS             17745..18254
                     /locus_tag="LP468_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081300.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18291..18692
                     /locus_tag="LP468_001764"
     CDS             18291..18692
                     /locus_tag="LP468_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081301.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18804..19157
                     /locus_tag="LP468_001765"
     CDS             18804..19157
                     /locus_tag="LP468_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081302.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19191..19634
                     /locus_tag="LP468_001766"
     CDS             19191..19634
                     /locus_tag="LP468_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2081303.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19651..20736
                     /gene="uxuA"
                     /locus_tag="LP468_001767"
     CDS             19651..20736
                     /gene="uxuA"
                     /locus_tag="LP468_001767"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2081304.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20729..21442
                     /locus_tag="LP468_001768"
     CDS             20729..21442
                     /locus_tag="LP468_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2081305.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7457 a         3323 c         4509 g         6354 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 ttatttctca tttaaacgat gtattcccta acctctaata catccttgta actctgaagt
     1381 tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt
     1441 tcgtgtttct ctagtataac agaataagag gaacaagtcc agaagggata tttttagtct
     1501 tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg
     1561 gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga
     1621 tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt
     1681 tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa
     1741 taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat
     1801 ttgtttattt gaatatattt tttacataag gatctttaat agttacattg tcttttttca
     1861 tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa
     1921 ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca
     1981 tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag
     2041 aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat
     2101 tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag
     2161 cttgaacaag cttggagaaa ttttcccctt catttgcttc tttttttgct ttatctgctt
     2221 cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag
     2281 cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca
     2341 gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt
     2401 ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg
     2461 aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata
     2521 gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc
     2581 cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg
     2641 cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct
     2701 tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct
     2761 gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt
     2821 ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga
     2881 tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt gttttaggaa
     2941 ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa
     3001 ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg
     3061 tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt
     3121 tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt
     3181 tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt
     3241 ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc
     3301 atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc
     3361 ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag
     3421 gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct attggtgctc
     3481 atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag
     3541 aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact
     3601 ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt
     3661 tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga
     3721 tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa
     3781 aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc
     3841 gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga
     3901 gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa
     3961 ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat
     4021 ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag
     4081 tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg
     4141 atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga
     4201 ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga
     4261 gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt
     4321 tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg
     4381 aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaagta
     4441 gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag
     4501 gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca
     4561 tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata
     4621 atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca
     4681 acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa
     4741 aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga
     4801 acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc
     4861 gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa
     4921 cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag
     4981 ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac
     5041 aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga
     5101 aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata
     5161 atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag
     5221 tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata
     5281 tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat
     5341 cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa
     5401 aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa
     5461 cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc
     5521 ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac
     5581 tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga
     5641 agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca
     5701 ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca
     5761 tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt
     5821 gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt
     5881 gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc
     5941 aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt
     6001 tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga
     6061 aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg
     6121 ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc
     6181 aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga
     6241 ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc
     6301 tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata
     6361 ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca
     6421 atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga
     6481 acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta
     6541 tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca
     6601 acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa
     6661 aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc
     6721 caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc
     6781 aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct
     6841 tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa
     6901 gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga
     6961 acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc
     7021 aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg
     7081 ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca
     7141 gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa
     7201 taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca
     7261 cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca
     7321 caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt
     7381 ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca
     7441 aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag
     7501 tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt
     7561 ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg
     7621 aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga
     7681 ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa
     7741 cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg
     7801 ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa
     7861 tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat
     7921 ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct
     7981 cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt
     8041 ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat
     8101 ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga
     8161 aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt
     8221 tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac
     8281 agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg
     8341 gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta
     8401 cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt
     8461 aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat
     8521 caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt
     8581 gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta
     8641 tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga
     8701 tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt
     8761 tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg
     8821 gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac
     8881 ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg
     8941 gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt
     9001 attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc
     9061 aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc
     9121 cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct
     9181 tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac
     9241 gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt
     9301 acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt
     9361 agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca
     9421 tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga
     9481 aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga
     9541 aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc
     9601 gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc
     9661 agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga
     9721 acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca
     9781 aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct
     9841 tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag
     9901 aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca
     9961 tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct
    10021 tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg
    10081 atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt
    10141 acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc
    10201 ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt
    10261 tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac
    10321 cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa
    10381 aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg
    10441 cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc
    10501 atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt
    10561 tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat
    10621 gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag
    10681 ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa
    10741 atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag
    10801 tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt
    10861 tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa
    10921 gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt
    10981 tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga
    11041 tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc
    11101 ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat
    11161 ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt
    11221 tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa
    11281 atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc
    11341 ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga
    11401 tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa
    11461 tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa
    11521 atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg
    11581 atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca
    11641 aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa
    11701 aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa
    11761 ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca
    11821 atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct
    11881 gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt
    11941 tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt
    12001 cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat
    12061 agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct
    12121 gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct
    12181 tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt
    12241 gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa
    12301 gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc
    12361 aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag
    12421 acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac
    12481 ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc
    12541 tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg
    12601 atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga
    12661 aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt
    12721 actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg
    12781 ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat
    12841 aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa
    12901 aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag
    12961 ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga
    13021 ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca
    13081 agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa
    13141 tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata
    13201 accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa
    13261 ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa
    13321 atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc
    13381 ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta
    13441 gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg
    13501 atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta
    13561 caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg
    13621 gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta
    13681 agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg
    13741 ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca
    13801 caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga
    13861 catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc
    13921 cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt
    13981 tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg
    14041 attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa
    14101 agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc
    14161 agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt
    14221 agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc
    14281 aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa
    14341 caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg
    14401 taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga
    14461 aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg
    14521 tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca
    14581 gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc
    14641 gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga
    14701 agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca
    14761 tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt
    14821 cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat
    14881 aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat
    14941 ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa
    15001 agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt
    15061 ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct
    15121 gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg
    15181 gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg
    15241 gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata
    15301 aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta
    15361 taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag
    15421 atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg
    15481 aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc
    15541 attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc
    15601 tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa
    15661 gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc
    15721 gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc
    15781 gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc
    15841 tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg gctgaattta
    15901 ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac
    15961 agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa
    16021 acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc
    16081 tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc
    16141 gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg
    16201 atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca
    16261 gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt
    16321 gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact
    16381 tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga
    16441 tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt
    16501 gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc
    16561 gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact
    16621 gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt
    16681 gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc
    16741 gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac
    16801 aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat
    16861 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
    16921 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
    16981 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
    17041 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
    17101 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
    17161 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
    17221 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
    17281 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
    17341 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
    17401 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
    17461 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
    17521 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
    17581 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
    17641 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
    17701 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
    17761 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
    17821 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
    17881 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
    17941 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
    18001 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
    18061 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
    18121 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
    18181 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
    18241 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
    18301 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
    18361 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
    18421 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
    18481 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
    18541 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
    18601 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
    18661 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
    18721 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
    18781 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
    18841 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
    18901 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
    18961 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
    19021 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
    19081 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
    19141 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
    19201 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
    19261 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
    19321 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
    19381 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
    19441 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
    19501 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
    19561 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
    19621 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
    19681 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
    19741 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
    19801 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
    19861 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
    19921 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
    19981 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
    20041 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
    20101 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
    20161 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
    20221 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
    20281 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
    20341 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
    20401 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
    20461 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
    20521 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
    20581 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
    20641 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
    20701 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
    20761 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
    20821 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
    20881 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
    20941 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
    21001 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
    21061 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
    21121 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
    21181 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
    21241 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
    21301 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
    21361 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
    21421 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
    21481 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
    21541 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
    21601 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tcc
//
LOCUS       DAFEML010000040        21280 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFEML010000040
VERSION     DAFEML010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.040"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP468_001769"
     CDS             131..505
                     /locus_tag="LP468_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2081306.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP468_001770"
     CDS             complement(619..1248)
                     /locus_tag="LP468_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2081307.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP468_001771"
     tRNA            complement(1382..1454)
                     /locus_tag="LP468_001771"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP468_001772"
     tRNA            1668..1741
                     /locus_tag="LP468_001772"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LP468_001773"
     CDS             complement(1879..2043)
                     /locus_tag="LP468_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081308.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LP468_001774"
     CDS             2338..3666
                     /locus_tag="LP468_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL2081309.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LP468_001775"
     CDS             3868..4701
                     /locus_tag="LP468_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL2081310.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LP468_001776"
     CDS             4717..5454
                     /locus_tag="LP468_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL2081311.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LP468_001777"
     CDS             complement(5609..6577)
                     /locus_tag="LP468_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL2081312.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LP468_001778"
     CDS             6809..7642
                     /locus_tag="LP468_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL2081313.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLSPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LP468_001779"
     CDS             7676..8515
                     /locus_tag="LP468_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2081314.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LP468_001780"
     CDS             8541..9101
                     /locus_tag="LP468_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2081315.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LP468_001781"
     CDS             9300..11021
                     /locus_tag="LP468_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL2081316.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LP468_001782"
     CDS             11186..12328
                     /locus_tag="LP468_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2081317.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LP468_001783"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LP468_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL2081318.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="LP468_001784"
     CDS             14128..14775
                     /locus_tag="LP468_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2081319.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="LP468_001785"
     CDS             15168..17813
                     /locus_tag="LP468_001785"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL2081320.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="LP468_001786"
     CDS             18123..19436
                     /locus_tag="LP468_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL2081321.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="LP468_001787"
     CDS             19426..20079
                     /locus_tag="LP468_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2081322.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="LP468_001788"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="LP468_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL2081323.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="LP468_001789"
     CDS             20976..21176
                     /locus_tag="LP468_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2081324.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7183 a         3551 c         4446 g         6100 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcagtcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta
//
LOCUS       DAFEML010000041        20942 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFEML010000041
VERSION     DAFEML010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.042"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            168..362
                     /locus_tag="LP468_001790"
     CDS             168..362
                     /locus_tag="LP468_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081325.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="LP468_001791"
     CDS             631..930
                     /locus_tag="LP468_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081326.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="LP468_001792"
     CDS             complement(1027..1461)
                     /locus_tag="LP468_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081327.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="LP468_001793"
     CDS             complement(1693..2403)
                     /locus_tag="LP468_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2081328.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="LP468_001794"
     CDS             complement(2393..3253)
                     /locus_tag="LP468_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL2081329.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="LP468_001795"
     CDS             complement(3258..3896)
                     /locus_tag="LP468_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL2081330.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="LP468_001796"
     CDS             complement(3911..4210)
                     /locus_tag="LP468_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081331.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="LP468_001797"
     CDS             complement(4253..5737)
                     /locus_tag="LP468_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2081332.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="LP468_001798"
     CDS             complement(5757..6218)
                     /locus_tag="LP468_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2081333.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP468_001799"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP468_001799"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL2081334.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="LP468_001800"
     CDS             7521..8291
                     /locus_tag="LP468_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2081335.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="LP468_001801"
     CDS             complement(8564..9391)
                     /locus_tag="LP468_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081336.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="LP468_001802"
     CDS             9959..11194
                     /locus_tag="LP468_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL2081337.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="LP468_001803"
     CDS             complement(12193..12453)
                     /locus_tag="LP468_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2081338.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="LP468_001804"
     CDS             complement(12480..13781)
                     /locus_tag="LP468_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081339.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="LP468_001805"
     CDS             complement(14073..14531)
                     /locus_tag="LP468_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2081340.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="LP468_001806"
     CDS             complement(14544..15875)
                     /locus_tag="LP468_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL2081341.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="LP468_001807"
     CDS             complement(15886..17328)
                     /locus_tag="LP468_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2081342.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="LP468_001808"
     CDS             complement(17315..18079)
                     /locus_tag="LP468_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL2081343.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="LP468_001809"
     CDS             complement(18183..19058)
                     /locus_tag="LP468_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2081344.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="LP468_001810"
     tRNA            complement(19313..19397)
                     /locus_tag="LP468_001810"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="LP468_001811"
     tRNA            complement(19415..19486)
                     /locus_tag="LP468_001811"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="LP468_001812"
     tRNA            complement(19496..19568)
                     /locus_tag="LP468_001812"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="LP468_001813"
     tRNA            complement(19630..19714)
                     /locus_tag="LP468_001813"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="LP468_001814"
     tRNA            complement(19735..19805)
                     /locus_tag="LP468_001814"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="LP468_001815"
     tRNA            complement(19851..19922)
                     /locus_tag="LP468_001815"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="LP468_001816"
     tRNA            complement(19934..20006)
                     /locus_tag="LP468_001816"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="LP468_001817"
     tRNA            complement(20009..20082)
                     /locus_tag="LP468_001817"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="LP468_001818"
     tRNA            complement(20089..20169)
                     /locus_tag="LP468_001818"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="LP468_001819"
     tRNA            complement(20171..20246)
                     /locus_tag="LP468_001819"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="LP468_001820"
     tRNA            complement(20282..20354)
                     /locus_tag="LP468_001820"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="LP468_001821"
     tRNA            complement(20364..20436)
                     /locus_tag="LP468_001821"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="LP468_001822"
     tRNA            complement(20452..20523)
                     /locus_tag="LP468_001822"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="LP468_001823"
     tRNA            complement(20538..20627)
                     /locus_tag="LP468_001823"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
     gene            complement(20667..20740)
                     /locus_tag="LP468_001824"
     tRNA            complement(20667..20740)
                     /locus_tag="LP468_001824"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20704..20706),aa:Asn,seq:gtt)
     gene            complement(20750..20865)
                     /gene="rrf"
                     /locus_tag="LP468_001825"
     rRNA            complement(20750..20865)
                     /gene="rrf"
                     /locus_tag="LP468_001825"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6604 a         4391 c         3330 g         6617 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgagaactcc ggcagtagga ctcgaaccta cgacatcatg
    20701 attaacagtc atgcgctact accaactgag ctatgccgga ataacatcag cgtggcgacg
    20761 tcctactctc acaaggggca acccctcact acaatcggcg ctaagaagct taacttctgt
    20821 gttcggcatg gttacaggtg tatccttctc gctatcgcca ccacactgtg gtgttatctt
    20881 ttattgagta aattttgttc actcaaaact ggatttgaag tcacataagt ttttttccga
    20941 gt
//
LOCUS       DAFEML010000042        20282 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFEML010000042
VERSION     DAFEML010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.043"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            137..457
                     /locus_tag="LP468_001826"
     CDS             137..457
                     /locus_tag="LP468_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081345.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            909..1109
                     /locus_tag="LP468_001827"
     CDS             909..1109
                     /locus_tag="LP468_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2081346.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1256..4045
                     /locus_tag="LP468_001828"
     CDS             1256..4045
                     /locus_tag="LP468_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2081347.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4092..4619
                     /locus_tag="LP468_001829"
     CDS             4092..4619
                     /locus_tag="LP468_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL2081348.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4640..5830
                     /locus_tag="LP468_001830"
     CDS             4640..5830
                     /locus_tag="LP468_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2081349.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5870..7168
                     /gene="asnS"
                     /locus_tag="LP468_001831"
     CDS             5870..7168
                     /gene="asnS"
                     /locus_tag="LP468_001831"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL2081350.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8221..8895
                     /locus_tag="LP468_001832"
     CDS             8221..8895
                     /locus_tag="LP468_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2081351.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8892..9233
                     /locus_tag="LP468_001833"
     CDS             8892..9233
                     /locus_tag="LP468_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081352.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9263..9622
                     /locus_tag="LP468_001834"
     CDS             9263..9622
                     /locus_tag="LP468_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL2081353.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10146..12227
                     /gene="cadA"
                     /locus_tag="LP468_001835"
     CDS             10146..12227
                     /gene="cadA"
                     /locus_tag="LP468_001835"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2081354.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12538..14004
                     /locus_tag="LP468_001836"
     CDS             12538..14004
                     /locus_tag="LP468_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2081355.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14619..15158
                     /locus_tag="LP468_001837"
     CDS             14619..15158
                     /locus_tag="LP468_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBL2081356.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15232..15672
                     /locus_tag="LP468_001838"
     CDS             15232..15672
                     /locus_tag="LP468_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL2081357.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15685..15894
                     /gene="copZ"
                     /locus_tag="LP468_001839"
     CDS             15685..15894
                     /gene="copZ"
                     /locus_tag="LP468_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL2081358.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15894..18080
                     /locus_tag="LP468_001840"
     CDS             15894..18080
                     /locus_tag="LP468_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL2081359.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18100..20271
                     /gene="copB"
                     /locus_tag="LP468_001841"
     CDS             18100..20271
                     /gene="copB"
                     /locus_tag="LP468_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL2081360.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6774 a         3527 c         4407 g         5574 t
ORIGIN      
        1 aagaggttgt gacgtggtca cgacctcttt ttgacgatta tgatacaaaa aacatcattt
       61 atgaacaaaa tgtgaataac gggcgttctt gagatatgat tttaattggg aaaaacttat
      121 cgataaggag gtctttatga aaaaaagact gttatggtgt ttgctgtttc tatccctaag
      181 tttaacaagt cagccagttt ttgctgaaga aacacagcgg tctcctatta caggcacacg
      241 tctgtacaaa aatgtttatg tacagacaac agatcttgat tctgcgattc ctgaaacaga
      301 agaacggtct ttgcagccaa gatttggtta cttttggtac tgtccgacct gtgattatga
      361 aagttgctgg catttcttac attctacagc tgcagctttt gcttttactc atactcagaa
      421 atatgatgga catcatcctg ttatttatga ggtatagata tgagcaaaaa agaaaaacta
      481 atctcgttga tcgtattggt ttgccttgtt cttctggtaa ctgtcatagg ctatcagaaa
      541 taccatgaga acatcagacc tactaaagaa tcttccccag cctcgaccgt tgaaacagaa
      601 ccgataagta gtcagaaaga ataatttttt tagtttaaag aagaacatca gagcaaaaaa
      661 acaccaactg aacaatatgt cgtttatttt aaaaaaagtt cggtttttca ctttatgtaa
      721 tcgctgagaa aacttttttt aataaaaaaa gtcgaaaaac tctagctttt ttgtaaacgg
      781 tatgatatac tataggagta gtttttgttc ggtaatctgt ggtagcttgt ttcaaataaa
      841 catcttccag atatacacca ttcaagtaat tgcaaaatat gtgttgatac acaaggagga
      901 tttttattat ggaaacaggt acagtaaaat ggtttaactc agaaaaagga tttggattca
      961 tcactgcaga aaacggaaac gatgtattcg ttcatttctc agctatccaa ggcgacggat
     1021 tcaaaacttt agaagaaggc caagcagtaa ctttcgatgt tgaagaaggc caacgcggac
     1081 ctcaagcaac aaacgttact aaagcttaat taacctatac taaaaaataa acgcccagac
     1141 atttgcgtgt ctgggcgttt ttgtctattt tctttaaaaa gcgatgagag tatttttctg
     1201 cactttgtag tataatttca aaagaacatt agaggcagga gaagaggaag atattttgaa
     1261 accaagaact tatgcagtcg ttgatatcga aacgactggg acgaatccaa aagaagatcg
     1321 gatcatccaa tttggctgcg tcatgattga atcaggtcgg atcacttcac gtttttcgat
     1381 cgatattcat ccagggcgga agatttcaaa acaaatccag catttaacag ggatcacgaa
     1441 tcaacgcgtc caaaaagcgc cttatttcga agatgtcgcc caaacgattt acaatctttt
     1501 ggcagacacc atatttgtcg cgcataatat ttattttgat tataattttt tgaaccatga
     1561 actcatgcga tgcggacttc ctagtttgaa gataccaggc atcgatacag tagaacttgc
     1621 acaaattttc ttgccgacgg aaccaagctt tcgcttagct gatttgtcag aaagccttgg
     1681 atttattcat gagaatcctc atcaggcaga tagtgatgcc gaagtgacgg gtcaacttct
     1741 tttgctgatc gaagaacgga tgagaaaatt gccaatcatc acgttagagc agattgcgcg
     1801 attaagtaga cacacaggta tggatacgag tcgtttcatt tatcatgtga ttgaagaaat
     1861 gaaagaaaaa ccagagccac ttgatccctc attagaaatc gtcgatgggc tagctttgca
     1921 gaaaaaagaa gtggaactat tcacatccgt ccattatggc gagcggacat atccaagaaa
     1981 aaaacaagca aaagaaaaaa tgtttggtaa aacactgatg tatcgaaaag aacagaacag
     2041 actgatgaat gcggtctacg accatttcac aaaagatgaa tcaaaagatt tgatgatcga
     2101 agcagctaca ggaatgggta aaacaatcgg ttatctgctg ccattgagtt atttggctac
     2161 acctgaaaaa cccgctgtca tcagtaccgt ttcgctagtt ttgcagcagc agatcataga
     2221 aaaagacatt ccattgctga atcaattgct agatcagccc atacaacctg taattatcaa
     2281 aagctatcgc cactatattg atttacagcg ttttaaaggc acacttgtgg aaccgccaga
     2341 acaaaaacaa tatgctttgt atcaaatggc ggtcttagtt tggctgacgc aaacgaagac
     2401 cggtgatttg gatgaattac atttaacaaa tttgaaccat tcattctttg cagatatcgc
     2461 gcacagaggt attggatttt tagcaagaaa tcagtcattt tacgaacaag actttgttcg
     2521 tttcttgcaa aagaaaatca ggcaaagtaa ttttttgatt gtcaatcatg cgtttttaat
     2581 acaagaaaca cagcgaaaag aaccattgct tccagctagt ccatttttgt tgatcgatga
     2641 agtacatcat ttgccggaaa tcgctgaaaa agtaaatgac aaacgattaa gtattaacta
     2701 tttccataaa caaatccagc aattagaaga accaaatcag ctgtttgacc gaatacaaag
     2761 ctatttaccg aaagaacatg aagccttacg ctggttatcg atttatcgag aagaactttc
     2821 tgcgctatgc gaagcacaga tttgtatggc agaaggatta atgagtttag tgagcggcaa
     2881 gcaacctaac ggacagtatc cagaagaagt catgatgaca aaagagatgt tggatcagct
     2941 gccactggaa tctgggacag ccattgatca cctgcagctt ttttatcagg agatccagca
     3001 gctacagtca caaatgcgtc tgacttttga gattatccaa gaaagctgga caaaccagat
     3061 gcggatcgat ttagcaagtt tatatagctt atttgatcaa ttagacaagc agtacttgct
     3121 gatggatcaa tggctggaag actggcgaga tcatttgatc cattggttcg ttcctgggaa
     3181 cacagcgcag cagatgattt ttcatctcca tgattttcaa gcggctatgt tgccgtcgac
     3241 tgtttggtat cctcgatatg atcgtattct ttatattgga ggaacgctga agatcggccc
     3301 taatcgacac tatctctcta agcggcttgg cattgaagca gcacctctta aagtgattgc
     3361 ctctccttat gattatgaga aacaggcaag gatctatgtg ccaaaagagg cacctgccgt
     3421 ccatcaagtc agcaatcaag catatatcga ttatttagag acagcactta caggtctgat
     3481 cgaacaagaa gatcggccaa tacttgtgtt attcacttct catgatgttt tgcagaaggt
     3541 ctatcagaaa atgcatctgt ctatgctaga aaaaggacga gaaatactag ctcaagggtt
     3601 tggcggaagc cgggagaagc ttttgaaacg cttcattttg tcagaaaaaa gcgtattgtt
     3661 tggcgctgac agcttttggg aaggtgtaga tttgcctggg gatgctttgc agatcgttgt
     3721 agtcacacgt ttacccttcg ataatccgct tcgcccgatg gtcaaagcta ggaacgctta
     3781 tttagaatca gaggggatca atccttttta ccaggaatcc gtacctaaag cagctttgaa
     3841 gttacgccaa gcattaggtc gcttgataag gacggagaca gatcgtggcg tattgcttat
     3901 tttggatcga agactagtca ctgcaaaata tggtgcacgg atcatccatg cattaccgaa
     3961 aaaagtaccg atcaaagagc tagctatgga ggaaatctat caggacatcc atgaattctt
     4021 aaagaaaaat gaagaaggaa gttagaggag ctgtcttttt tcataattaa aatctgctat
     4081 aatgaaaagg aatgaagata aaggagcgac gacccttgaa gaaaaaacag acaaaggaaa
     4141 aaacgattaa tcgcgtgtta cttggcttga tcgtattttt attagcggtc atcgtgatca
     4201 gctcgatttt ttacttgcgt tccagtcgtc cggcggtgca ggcgaagaaa gaagcagtag
     4261 aaatcgcaaa gaaatatgca aatcttgagg aagccgatca tttttattgg tttactcgaa
     4321 agaagacata cttttcactg acaggtacaa atgataaagg aaaagaaatc gccgttatca
     4381 ttcctaaatc tggtgaaaaa gtaaaagtat tggatcaaac aaagggactg actgaaaacg
     4441 aagcaaaaca gacaattgct gcggcccatc ctgaaatcca aatcgaaaaa gctgctttag
     4501 ggatgtatga tgatcagcct gtgtgggaag tagtaggaaa agaaacaaat gggaaactga
     4561 attattacct gattggcttt gaatctggag atgaagtcaa gacaatcaag ggaatttaaa
     4621 aggtaaagga atgaatggga tggagttatc aaaaagaaca aaacgattag aaccgtctgt
     4681 cactttggca gctgcggcaa aggccaaggc attaaaagca aaaggcagag atgtgctgag
     4741 tttgactgtg ggagaaccgg attttgcgac accagaaaac atccaagaag cagcaatcga
     4801 agcaatccgc aacgggaaag ctagctatta tacaccaaca gcaggaatcc cagagcttcg
     4861 acaggcaatc gttgattatc tgaagaaaaa ctatggactt gtctatgaac cttcacaaac
     4921 agtcgtaaca gacggagcga aatttgcttt gtataccctt ttccaaacga tccttgaccc
     4981 gcaagatgaa gtcatcattc ctgtgcctta ctgggtcagt tacggtgagc aagtaaaact
     5041 ggcagaagga cttcctgtct ttgtgaaagg ggaagaatcc aatagctgga aagttactgt
     5101 tgaacagcta gaacaagcac gttcagaaaa aacaaaagcc gtaatcatca attctccatc
     5161 gaatccgact ggaatgattt atagcaagaa tgaactgcag gcaatcggtg aatgggcagt
     5221 aaaaaatgat attttgatag ttgctgatga tatttatggt cgtttagttt ataatggcaa
     5281 tgagtttact ccaattgcaa cgatttcaga agcaatcaaa aatcagacta tcatcatcaa
     5341 cggcgtgtct aaaacatatg cgatgacagg ctggcgcatt ggttatgcgg tgggaaatcc
     5401 tgtgatcatc aatggaatga tcgctgttgc ttcccagtca accagtaatc cgacagcagt
     5461 cagtcaatat gcagctgttg aagcattgaa aggcgagcaa gatacagtgg aagaaatgcg
     5521 gaacgccttt gaagaacgcc tgaatacgtt atattcgctt gtggcagaac tgccgggtgt
     5581 ttctcttgaa aagccacaag gagcttttta tctttttcct aatgtaaaag aaacgctacg
     5641 catgtgtaaa tatgaaaatg tcacacaatg ggtagaagat cttttagaag aaacaggggt
     5701 agcgcttgtg actggcgaag gctttggggc accagaaaat gtccgcatga gttatgctac
     5761 tgatcgcgct acgttagaag aagcggtacg cagaatcaag caatttattg agagtaaaag
     5821 tcaaaattaa tcctaaagaa attcaaggaa tataaaagga gagtcatacg tggaacaaat
     5881 tcaaatcatc gattcgaaaa accatgtggg agaaacagta acaatcggcg cttgggtcgc
     5941 aaataagcga tcaagcggaa aaatcgcatt tttacaatta agagacggaa cagccttttt
     6001 ccaaggtgta gttgtaaaaa gcgaagtgtc ggaagaagtt ttccaaacag ctaaaaatct
     6061 acaccaagaa acatccgtgt tagtaactgg agaaatccgt gaagacagtc gttcaaaatt
     6121 tggttatgaa atcggaatta caaatgtgga agtggtaagc gagagccacg attatccgat
     6181 cacaccaaaa gaacacggaa cagacttctt gatggatcat cgtcatttat ggctgcgttc
     6241 ttcaagacaa catgcgatta tgcagatcag aaatgaaatc attcgtgcaa cgtatgaatt
     6301 ctttaatcaa catcattttg tcaaaattga tccgccgatc ttgactggtt ctgcaccaga
     6361 aggcactacg gatctattcg aaacaaatta ctttgatcaa aaagcttatt tatctcaaag
     6421 tggccaatta tacatggaag ctgctgctat ggctttcgga aaagtctttt cattcggtcc
     6481 gactttccgt gctgaaaaat caaaaacacg acgtcatttg atcgaattct ggatgatcga
     6541 accagaaatg gctttcactc atcaagaaga aagtttagaa gtacaggaac aatatgtagc
     6601 attcttagta caaaatgttt tagatcattg cgaatatgca ttagatgtac taggacgaga
     6661 caaagaagtc ttaaaaactt atacaaaatt gccattccct cgtattactt atgatgatgc
     6721 gatcgaatta ctgaagaaaa atggatttga tgacatcgaa tggggcgaag actttggttc
     6781 acctcatgaa acgttcattg cgaattcatt cgaacagcct gtctttatcc taaactatcc
     6841 aaaagccatc aagccattct acatgaaacc acatccaaca agagaagacg tggtgatctg
     6901 tgcagatatg atcgcaccag aaggttacgg tgaaattatt ggcggaagcg aacgggcaac
     6961 agactatgat ttcttgctag aacaaatccg taatcacggt ttggatgaaa aagaatattc
     7021 atggtatctt gatctacgta aatacggttc tgttccgcac tctggttttg gtctaggtct
     7081 tgaacgaaca gtcacttgga ttgctggtat cgaccatgta cgtgaagcta ttccattccc
     7141 acgtttgttg aaccgaattt atccataaga ggtgatgaaa aagctgttct gcatcaagta
     7201 attagaacag ccaagcaaaa acagctgttc atgtttttga attggcggga cttattaccg
     7261 cagatgtaag cttttgaata ccgtttagtg gagaggttgt gaaaaagctg tttagtttcg
     7321 agtattaaga aaaattttgt ggaaatggct ttccacattt ttgcataaat ttggcttaat
     7381 accgagaaac tggcttttga acaccgttta aggaagaggt tgtgcgcctg ccgttcagct
     7441 ccgagtcaca aggagtaatt tcaaaaaaca gtttttcatg tttgatgact attgtgactt
     7501 gtgaccgagg agttggccgg agagcaccgt ttattctaaa aaagaactgc gaactctcgc
     7561 agttcttttt ttaaaatacg ggataaagga agtttccagc agacaagaga agaaagcaaa
     7621 agaaattgct atttgattca caaggttcta taacgaaatc gcaatcaatc aaacatttac
     7681 aaagaaggta attcaaatgg aaatctgatt tgatgatgct tctgctgttg aaataaagca
     7741 gcatctagca cctgaaaaca aactaatagt aacattcgaa gatggagtag gtccgtattt
     7801 tcagcatgca ataatccata tgtaagttca attcaccctt gaaatcatcg gaccagataa
     7861 agttatgacc aatctatccc aagcaatcta gaagagatat tagtaaaggg acatttacta
     7921 gaagtcttag atgagcctat aaatatatgt tctgatggcg tcatcagtgg tctgattgac
     7981 ggaagcttag gtgtgatcga tctctctgga ccaaacaacg aaggaatcaa ggggaatccg
     8041 gcacgttaag aaaaaaatag cataaaaaac tagacacttg atgagcgttc attcaattgt
     8101 ttgaagggac taggctggtg tcatttttta tacatatatt ttctctttcg tcttgatagg
     8161 gcttatggga taatataagg aagaaaatca tcgttttatt caaaaaggag tttttgacaa
     8221 atgaaaaaac gtatattatt tatcggtgat agcattacag acgcaggaag agaccgagca
     8281 gaagcaactg atctaggtaa aggttatcca cttttgattg ccggaaaact aatctcccaa
     8341 tatccaacga tggaatttga atgcatgaac cgtgggatag gaggagacaa aattgcagat
     8401 ctgcaagtac gctggcaaga agattgttta gctttacaac ctgactatgt atcgattttg
     8461 atcggaatca atgatacctg gcataatact agcgatcagg ctatattcgg aactgagaaa
     8521 tctgctcagc aatttgaatc cgtttatcga aaattactaa atgaacttca aacagtggga
     8581 atctgcaaca tcatcttgat ggagccgttt gtacttccta taaccgacga ccgtcatggc
     8641 tggcgtaaag acttagaccc taaaatccaa attgttcgta aacttgctaa ggaatatggc
     8701 gcattgctgg ttcctttaga tggtatattc aatgctttag ggattgttta tggtttttcg
     8761 aaatatacaa gagaagatgg ggtccaccca acgattggcg gacatgagat cattgcacaa
     8821 agctggatag atgcaattgc cgcagtcgat ttttttagtg gagataaaaa tgagcgaaag
     8881 aaaagtgaga aatgatggaa atacggtggg cagtaaaaga agatctacct caaatcaatc
     8941 agctgattac tgatcatcca gaatcattcg taaaagcaaa aacggcagct gacctaaatg
     9001 ataagaataa actattgctc gttgctgtaa caaaagaaaa acggattatc ggatttgcgc
     9061 aagcggacgt gcaacagtca gaagaacgat tggatcagcg accatcagga aaactaatcc
     9121 aacacacatt agtaacaaaa gaaaatacgg aagaaatcca aaaaaaattt gcagaatatt
     9181 tgatactgga agctaaaaaa agaagaataa aatcattttt tgcccagttt taatcaaaaa
     9241 cagtaataga aggagaaata caatgagttg tttaggaaat gtcatctggt ttatattcgg
     9301 cggactaatc ggtggtctta gctggttagc agcggggata ctttggtgta tcacgatcat
     9361 aggtatccca atcggtatgc aatgttttaa gatcgcctcc ctttcttttg cgccttttgg
     9421 caaagaagta atttatcacc agtctggcat gtcattgatt gttaatatca tctggctgat
     9481 cgtttcaggc ctaccaattg ctctcgcaca tgtcgtcagc ggcatccttc tatgtatcac
     9541 gatcataggg ataccttttg ccaagcaatc tttcaaactt gctcgattgg cgttgatgcc
     9601 attcggtgca gaaattgtat aaaagagaat aataaaggtt agataaagca tagagtcagg
     9661 tgggatacat gtatttcacc tgactctatg cgttctcctg tataagttct tccatgtgac
     9721 ttttacgtct tttatttata tggggttact gtttatggaa agttgaaata attttcatta
     9781 aagaactctt tctatatttt tgaaagcgta gtggagcttc gaatatctgg gaaggacatt
     9841 ttgcagggat tgaaaaaaga tattgtccta tcgaaaaatt aatgaattta gacaaattgc
     9901 cagcaacagg cttcaaactt agttgctatc ctgtcaagat caagaaggca agtgcgggtt
     9961 ggataagagc agtggcaatg atcgaaaaga aaaagaaaga ataagccaaa acatctgtat
    10021 ggaagaaatt ttccgatgca gatgtttttc attttttctt tcggatacct tgacatatga
    10081 ataaccgttc atttataatt agttatgaag agatattcat atgttgaggc gaggaggtca
    10141 ttaaaatgaa aagttacaga ttagaaggtt tagattgtgc gaactgtgca atgaaaatcg
    10201 aaaaaggagt tcagaagatc aatggagtca aggaagcaac ggtaaacttc acttctggaa
    10261 aactaacgat tgacgcagag gaagatcatt tggctacgat tgaacaagaa ataaaaaaag
    10321 tagtgaagga attagaacca gatgtcaaag taacagaaat agataaggaa aaagtatctg
    10381 aacatggaaa tgaaaaagag agaaatacgc tgttccggat tttattttcc cttgcaggta
    10441 tcgctttatt gctattattt gattttaatg aaccaattcg cttgataggg tatttattga
    10501 tttatctgct gataggatat gatgtagtga agaaggcagt gatgaatatc gtcaaaggaa
    10561 aaatctttga tgagaatttt cttatgtctg ttgctacgat tggcgctatg ttgatcggtg
    10621 aatatccaga agccgtagca gtgatgctat tttatcaaat cggcgagtat ttccaaggat
    10681 tggcagtcag tcattcaaga aaatcgattc gcgaattgat ggcgatccgt ccagaaacag
    10741 ctcacgtgca gacgacggaa ggattgatga ccgtgaaccc tgaagacgtg cagatcggtc
    10801 agtttgtact tgtgaagcct ggtgaacgtg taccgttaga tggaacgatc atcgaaggag
    10861 aatcattagt cgatacgtca gcacttacag gagaatcagt ccctaaatct gtatatgttg
    10921 gtgaaacagt attaagtgga tttatcaata aaaataaacc atttttagtt caagtagaaa
    10981 aatcttatga aaattctact atcagcaaat tattagaatt agtagaaaat gccagcagta
    11041 aaaaagcacc agctgaaaat ttcattacta aattcgcgcg ctattacaca ccagtcgttg
    11101 taggattggc cgttttatta gctgttttac ctccacttgt tgtttctgga gcggcgtttt
    11161 ctgaatggat ctatcgagca ttgacatttt tagtgatctc atgtccatgt gcattagtga
    11221 tctccgtacc ccttagtttc tttggcggta tcggaggagc aagtaaaatc ggtgtattag
    11281 taaaaggttc aaattacttg gagttgcttg cacaaactga gacagtggta ttcgataaaa
    11341 ccggcacatt aacgaaaggt gacttttcga tccagacgat cgatacaaaa atcgatccaa
    11401 agatattcat gcaatatgtt gcgagtgcag aacagttttc tacacatccg attgctcaat
    11461 ctgttttaga aggctacgca ggtccgcttt taccaacagc taatatccaa gaatttgcag
    11521 gtgaagggat cttagctgaa gttgatggca aacaagtatt agcaggtaat cacaaattga
    11581 tggaaagatt tgaaatctct tttccttcaa gtcaagaaat cggtacattg ctttatctag
    11641 cgatcgatca aagttacagt ggttatcttg ttattgcaga taccttgaaa gaagatgccg
    11701 tagacgcatt ggttcaatta aaaaaggctg gtgtgaagaa cacagtcatg ttgacgggcg
    11761 attcgaaaaa aattgctgat catatcggga agcaagtagg cgtggacaag atatatagcg
    11821 aattgcttcc agaagataaa gtgcagcggt tagaggaaat cttacaaaga aacaataaaa
    11881 agaccgcatt tgtcggagat ggaatcaacg atgcaccggt gctagcaaga gcagatgtag
    11941 gaatcgcaat gggtggattg ggaagcgatg ctgcaattga agcagcagat gtagtcatca
    12001 tgaatgatca accatcgaag attgcagaag caatccattt agcaaagaaa acattgaaaa
    12061 tcgtcaaaca gaacattgtc tttgctattg ggataaaaat tttggtactt gccttaggtg
    12121 cttttggttt tgcatcaatg ggagatgcag tatttgcaga tgttggggtg acagtattag
    12181 ctgttttgaa tgccatgcga agcttgcatg taaaaaataa acgttgatca atgaagagga
    12241 cgaatgaacg tcctcttttt tttatatcct tttcttaatg aaaaatgtaa agaaaataga
    12301 taggattata aaataactaa tgtttttaat tttgcagaaa attcaaaata gcttgaaatt
    12361 caataaggta aatgaaataa aagaaaataa cttatttttt tgatggaaaa aatatgaaaa
    12421 aacgatgtgt attaaataaa agaatacaca cataaaataa cactgtcttg taagtttgtt
    12481 aaaaattgaa tatgattaca tctggataac aaatttttat cataaaggag agaacgaatg
    12541 aacaacaaac aattacgctg gtttactgtt gcgttaattg catttaacat ggtttggggc
    12601 atggggaatg tagttaataa ctatgctcag caaggagtat cagttgtcac ctcttggcta
    12661 ttgattttgg ccatttattt tattccatac gcattgatcg ttggacaatt agggtcagcc
    12721 ttcaaggata gtaaaggagg cgtcagttca tgggtcgaaa atacgacatc taataaacga
    12781 ctggcatact atgccgcttg gacttactgg gtcgtccata ttccttattt ggcacaaaag
    12841 cctcaagcaa tcctgattgc tggcggttgg gcagtccaag gaaatggaaa tatcgtaaat
    12901 acgatgtcag tacaaatggt agcagttatt tcacttatta tatttcttgc ctttttatat
    12961 ttatcaacaa aaggactttc tactttgaaa gtgattggcg gactggccgg aacagcgatg
    13021 ttcgtcatgt cgatcttatt tattctttta gctgtaacgg caccgttcat caatccaacg
    13081 atggaatttg ccacaccaca tatgaatcaa gtgaaaacat atattccaac atttgatttc
    13141 agttatttca caaccgtttc gatgctagta tttgcagttg gaggagcgga aaaaatatcc
    13201 ccttatgtca actctacaag aaatcctgca aaggaatttc ctaaagggat gatcttctta
    13261 gcagcaatgg tagggatttg tgctgtatta ggctcagtcg caatgggtat gctgtttgct
    13321 agcgataata ttcctaaaga cttgatggca aatggggcat acagtgcttt tcaaatttta
    13381 ggtaattact atggtatcgg taactcattg atgatcattt acgcattgac aaacatgatt
    13441 ggacaaatct ccgcattagc cttttcaatt gatgcaccac taaaaatctt gttagcagat
    13501 gcggatccag aatttgtacc aaactggcta cgtaaacgta atcgtaaagg tacattggtg
    13561 aatggttatc ttctgacagg tatactagta ggaatcatta ttttgttgcc gatctttggt
    13621 atcaaagata tgaatgaatt agtaaaatgg ttgacgaact tgaactcagt tgtcatgcca
    13681 atgcgttacc tatgggtgtt cttggcatat atgatgttga ataaagctta taagaaattc
    13741 aattctgaat ataaatttgt taaaaatcca aaaatcggtt ttatctttgg tgcttggtgc
    13801 tttgccttca ctgcgtttgc atgtatccta ggaatggtgc caaaagtaga ttatactgct
    13861 gatcctaaag catggtggtt ccaattattc acgaatatca tcacaccaat tgtcttgatc
    13921 ttattaggta tgatcttgcc agcaattgct cgtcgagaca aaaacaaaga aatcactgaa
    13981 ccagaaacag tggttcagcc ttaaaataga aatacttgtt acaagaggtt gtgacagaag
    14041 tggtcagctt caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaag
    14101 tttcggcttg tttttcgcag aagctacttc tggaacaccg tgaatcagag gttgtgaaaa
    14161 agctgtcctg catcaagtaa taagaacagc caaacaaaaa tagcccctca tatttttcgt
    14221 tttgctgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa agaggtagtg
    14281 agcctgccgt ttaactccga gtcacaagga gcaatttcaa aaaacaactt ctcatgtttg
    14341 ttgactattg tgccttgtga ccgaggtgtt ggcaggagaa caccgtttaa ggaagaggtt
    14401 gtaaaatcag cgatttgacc tgagtattag aggaacaaac gaaaaaatag ctcctcatat
    14461 tttgccgttt tttgagttaa tgctgaaggt cagctgattg aacaccattt attcgaaaca
    14521 agggactttg acacgacttt tgtcacagtc ccttgttttt ttgcggcgtt ataagtggta
    14581 tgatcgaacc aaattccaaa gagaagtgag ggagaagaat gaagatcatc gtgattggac
    14641 aaagtgggtc gggaaaatcg accctcgcaa ggaagatcaa agaaatcacc gactttccgc
    14701 tactgccgct agacctttta tggcatacaa cagactacag tattcaggca aaaaagtggt
    14761 ttttgcaaga acagcaatcg tttatggtat ctaatccgtc atggattgtt gaaggaaatt
    14821 atacttctac attagaggaa aggattaaag aagcagataa gatcatttgg cttaaagtgc
    14881 cgcgttatct cgccatctac cgagtagttt ggcgttctct aaaaagaaag ataaacaaaa
    14941 aatctcggcc agatatgcct gaatcatttt cagagaaact aaacagggaa tacttagaat
    15001 ttttatcttt tatctggcat tttgaagaaa acaatgaacc gaaaatacag cagctgatcc
    15061 aagtagctaa tgcaagaaat aaactgatca tccttaaaac aagacgagag aaacaagaat
    15121 ttttaactaa attgaaaata gagagcaaaa ataattgaca gtttttgttt acaagcgtaa
    15181 tctgtattca taagctaatg attacatttg taaacgaaag gtgtgaaata aatggaaaaa
    15241 gtcaaaacgc cagtaaagat cagtgattca gagtgggaga tcatgcgtgt tatttggaca
    15301 cttggacaga cgacagccca agaaatcacg cagatcttag ctgattcgat ggattggaaa
    15361 ccagcaacga tcaaaacttt gctgggacgt ttggtaaaaa aagaagtgat ctggacagaa
    15421 caagaaggaa aaaaattcat ttatcatcca gctgtctcgg agatggaaac agttcgcagt
    15481 gcgacggaaa atcttttttc ccatatctgt gcaaaaagga ttggagagac gattgcggat
    15541 ctagtagaag aagccacttt gactcaagaa gatatcaatg agattttgaa acaactggaa
    15601 caaaagcaac cagtagatac gatcgaatgt aactgtatcc caggtcaatg tgaatgtaaa
    15661 caacatcaat aggaggaaga aaaaatgaaa caacaatttt caatcgaagg tatgagctgc
    15721 aatcattgtg cagcaagagt agaagaaaca gtaagcgcac ttgacggcgt gcaaaaagtg
    15781 aaagtaaatt tgaaaaaagc aaacggtacg gtcaagtttg atgaaacaaa agttcaatcc
    15841 gaaaagattt gtcaagcaat caatggattg ggttataaag cagaggtgat ttgatggcaa
    15901 cagcagaaac caaaatggat acgttcgtca ttacaggtat gacttgtgca aattgttctg
    15961 ctaggatcga aaaagagctg aacggacaac ctggtgtggt caatgccaca gtcaacttgg
    16021 ccactgaaaa agcaagtgtc aaatatgaag ggacgaccac tgaaaaatta atccaaagcg
    16081 tagaaaacat cggttatggt gcaattttgt acgatgaagc ccacaaacaa aaaattgcag
    16141 aagaaaagca agcgtatttg aaaaaaatgc tattcgatct tatattgagt acggttttga
    16201 ctttgccgtt gatgttgtca atgattgcta tgatgttagg aagccatgcg gcgattgttc
    16261 acttttttca ttttccaatc gtccagttag tgctgtctgc tcctgtccaa ttttatgtcg
    16321 gtgctcgttt ttataaaggt gcgtaccatg caatcaagac gaaagcacca aatatggatg
    16381 tattggtagc aattggaaca tcggctgcct ttgcattgag catttacaac ggatttttcc
    16441 gtggacaccc ccaagatctt tattttgaaa gcagcagtat gatcatcacg ctgattttgc
    16501 tcggcaaata tttggaacat acagcaaaaa cgaaaacagg taatgcaatc aaacaattga
    16561 tgtctcttca aacaaaaacc gcccaagtga taagaaacgg gaaagaagaa acgttagcga
    16621 ttgaagaagt agtcgttggt gatcaactag tcatccgtcc tggtgagcag attccagcag
    16681 atggtcgaat tatttcagga agcagtgcga tagatgaaag tatgcttact ggtgaaaatc
    16741 ttcctgtaga aaagaatccg gatgacacgc tttttggcgg gacaatcaat acgaatggtc
    16801 tgctacacat ggaagtcaca caagtcggca agcagacagt attagcgcaa atcattcaaa
    16861 tggtggaaga tgctcaaggg agcaaagccc caatccaaaa aatcgcagat cggatctcag
    16921 ggatttttgt tccgatcgta ttagtcatcg cgtttatcac gctcatagct acaggtttga
    16981 tcactggtga ttggcaactc gcattgatcc atagtgtctc tgtattagtc attgcgtgtc
    17041 catgtgcatt aggtttagcg accccaacag ctattatggt aggaacgggt gttggtgcac
    17101 gaaatggaat tttaattaaa ggcggagaag cattagaagc agctgctcac ttagacagca
    17161 ttgttttgga taaaactgga acgattacag aaggaaagcc caaagttaca gatctagtcg
    17221 gttcaaaaga agtcctatct attttttata ctttagaaca agcttctgaa catccactag
    17281 gtaaagcaat cgtggaatac ggaaaactgc aagaagcagc aacatacgat atgattgatt
    17341 ttacagccca cccaggtgct gggatcagcg gtacgattaa tggagtacgc tattttgcgg
    17401 gtacacgtaa acgattaatt gaattgaacc tatcatttga tgaataccaa gaacacgcgt
    17461 tagaattaga acagcaggga aaaacagtca tgtttttagc tgatgaaaag caagtgatcg
    17521 ggtggattgc cgtggctgat caaatcaaac tagaagccaa acaagcaatc aagcagctcc
    17581 agaataaagg attagatgtt tttatgctga caggagacaa caaactggca gccgaaacga
    17641 ttggtaaaca agttggtatt gatccaaagc atatctttgc tgaagtactt ccagaggata
    17701 aagcagccta cgtagaaaaa cttcagaaag atggcaaaaa agtcggtatg gcaggcgatg
    17761 gaatcaatga tgcaccggcc ttagcattag ctgatgtcgg tatggcaatg ggaagtggaa
    17821 cggacattgc gatggaaaca gccgatgtga cgctgatgaa tagcagtttg gcatccattg
    17881 cacaaacaat cgagttgtct aggttgacat tgagaaaaat caaacaaaat cttttctggg
    17941 cttttgtcta taatacgatt ggtattcctt ttgccgcact aggctttttg aatccaatca
    18001 ttgcaggagg agcgatggcg tttagttccg tcagtgtatt gttgaactcc ctgagcttaa
    18061 atcgacacat gaaaaagtaa gagaagggat ggagtaaaaa tgaatgggaa cgatatggag
    18121 aaaaaacatg agcataaaaa agaagtagta aacaaagaaa gtacagaatc tcatgaaaaa
    18181 cagatggaga tgaaacatga ccatagtcag atggatcatt ccatgcacat gggacataac
    18241 catggagata tagcaaacag caaacaaatg gaccattcga tgcacatgga tcacgaacac
    18301 ggcggcatgg atcattccat gcacatgggg aatttcaaac aaaaattttg gctatcgctt
    18361 atcctagcta tcccaatcat tcttttttca ccaatgatgg gaatggaatt tccatttcaa
    18421 gtaacgtttc ctggttctga ttggctcgta ttgatcttag caactatact atttatctat
    18481 ggcggtcagc catttttaag tggagctaag atggaattga aacaaaaaag tcctgctatg
    18541 atgacactga tcgcgatggg gattacagtt gcatatattt atagtgtcta ttcgtttatc
    18601 gcaaatctgc tcaatccaca tacacacgtc atggatttct tctgggaatt ggctactttg
    18661 atcgttatta tgctactagg tcactggatt gaaatgaatg ctgtgtcgaa tgccagcaat
    18721 gctttacaaa aactagcaga attactgcca gaatcagtga aacgcttgac gaaagatgga
    18781 aaagaagaga cagtttcatt gaaagaagta aacgaaggtg atcgtttgat cgtccggtct
    18841 ggtgataaaa tgccaacaga tggtgtaatc ttgaaaggtg aaacaattgt tgacgaatca
    18901 gctgtgactg gcgaatcaag aggaatcaaa aaacaagcca atgacaaagt gattggcggt
    18961 tctatcaatg gggatggaac gatcgaaatc gaagtaactg gaactggtga aaatggttat
    19021 ctagcgaagg ttatggaaat ggtgcgaaaa gcacaaggag aaaaatccaa gctagagtca
    19081 ttatctgaca aagtggcaaa atggctgttt tatgtcgcat taattgtggg tatcctggca
    19141 ttcatcgcct ggttgttctt gacagatctt cctaatgcat tagaacgtat ggtaacagtc
    19201 tttatcatcg cctgtcctca tgctctaggt ttagctatcc cattagttgt tgctcgctcc
    19261 acatcaatag cagctaaaaa cggattactt ttgaaaaacc gcaatgcact ggagcaagcc
    19321 aatgatctag atgtgatcat gctggacaaa acaggaacac taacagaagg aaaatttact
    19381 gtaacgggtg tcgaagtact tgatgatgcg ttcaataaaa atgaaatcct tcaatatcta
    19441 ggagccttgg aagcgaatgc caatcatcca ttggctgttg gcattatgaa ttatttgaaa
    19501 gaacatgaaa tcaagcctta tcaagctgaa aatctaaaaa atctttcagg agtcgggcta
    19561 gaggcaacag tcaaaaaaca acaagtgaaa atagttaatg aaaaagaagt tgagcgtctc
    19621 ggattaaacg tagaacaagc attattgaaa ccttaccaag aacaaggaaa taccatcagc
    19681 ttcctgattt tagaaaatca tctagctgca atcgttgctt taggtgacgt agtaaaaaca
    19741 gaagcaaaag aatttatccg aacattgaaa gaaagaaaaa tcactcctgt catgcttact
    19801 ggtgacaata aaaacgctgc ccaagcagta gcagattatt tagggatcga agaatattat
    19861 ggcggtttat taccagatga taaagaagct gttgtccaga aataccttga ccaagggaaa
    19921 aaagtaatca tggtgggtga tgggatcaat gatgcgccaa gtttagcccg tgcttcaatc
    19981 gggatggcaa tcggtgcagg gacagatatc gcaatcgatt ctgcggatgt cgtattgaca
    20041 aacagcgatc caaaagatat tttgcatttt cttgatctag ccaagcaaac gcgaaagaaa
    20101 atgatccaga acctctggtg gggggcaggt tacaatattc ttgcaattcc gctagcagcc
    20161 ggaattcttg cgccaattgg tatcatatta agtccagcag ttggtgctgt cttgatgtcg
    20221 ttaagtacgg tagttgtagc tctaaatgct ttgacattga aaatcaaata ataatgaaaa
    20281 aa
//
LOCUS       DAFEML010000043        19258 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFEML010000043
VERSION     DAFEML010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.044"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..883
                     /locus_tag="LP468_001842"
     CDS             <1..883
                     /locus_tag="LP468_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL2081361.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            931..3060
                     /locus_tag="LP468_001843"
     CDS             931..3060
                     /locus_tag="LP468_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL2081362.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3035..3724
                     /locus_tag="LP468_001844"
     CDS             3035..3724
                     /locus_tag="LP468_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081363.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4132..4818)
                     /locus_tag="LP468_001845"
     CDS             complement(4132..4818)
                     /locus_tag="LP468_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081364.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4954..5148)
                     /locus_tag="LP468_001846"
     CDS             complement(4954..5148)
                     /locus_tag="LP468_001846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081365.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="LP468_001847"
     CDS             complement(5198..5638)
                     /locus_tag="LP468_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL2081366.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="LP468_001848"
     CDS             complement(5642..6487)
                     /locus_tag="LP468_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL2081367.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="LP468_001849"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="LP468_001849"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL2081368.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8111..9058)
                     /locus_tag="LP468_001850"
     CDS             complement(8111..9058)
                     /locus_tag="LP468_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2081369.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(9281..9631)
                     /locus_tag="LP468_001851"
     CDS             complement(9281..9631)
                     /locus_tag="LP468_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2081370.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            9831..10910
                     /gene="pepA"
                     /locus_tag="LP468_001852"
     CDS             9831..10910
                     /gene="pepA"
                     /locus_tag="LP468_001852"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL2081371.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            11054..11374
                     /locus_tag="LP468_001853"
     CDS             11054..11374
                     /locus_tag="LP468_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2081372.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            11396..11860
                     /locus_tag="LP468_001854"
     CDS             11396..11860
                     /locus_tag="LP468_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2081373.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            12065..12670
                     /locus_tag="LP468_001855"
     CDS             12065..12670
                     /locus_tag="LP468_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL2081374.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(12709..13998)
                     /locus_tag="LP468_001856"
     CDS             complement(12709..13998)
                     /locus_tag="LP468_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL2081375.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            14426..14905
                     /gene="rlmH"
                     /locus_tag="LP468_001857"
     CDS             14426..14905
                     /gene="rlmH"
                     /locus_tag="LP468_001857"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL2081376.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15108..15658
                     /locus_tag="LP468_001858"
                     /pseudo
     CDS             15108..15658
                     /locus_tag="LP468_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            15729..16898
                     /locus_tag="LP468_001859"
     CDS             15729..16898
                     /locus_tag="LP468_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBL2081377.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            17200..17892
                     /locus_tag="LP468_001860"
     CDS             17200..17892
                     /locus_tag="LP468_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2081378.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            18320..18712
                     /locus_tag="LP468_001861"
     CDS             18320..18712
                     /locus_tag="LP468_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081379.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(18885..19067)
                     /locus_tag="LP468_001862"
                     /pseudo
     CDS             complement(18885..19067)
                     /locus_tag="LP468_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            19054..19251
                     /locus_tag="LP468_001863"
     CDS             19054..19251
                     /locus_tag="LP468_001863"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081380.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
BASE COUNT         6384 a         3336 c         3727 g         5811 t
ORIGIN      
        1 tatttcagta ccggttgcac tgttctcatt tatgggctcg attatggctg gaatctttgc
       61 taatatcgtc aatttcaaac aatatcaaac gatttatgct ggtttcaatc cagcggctga
      121 aagctatact tataatgact atttccaaat tggtatgatt gggatgattg taagcttagt
      181 tgtggtacta acggtcgcta atatatcaat gaacaaaaag aaacgctatg caatggcagc
      241 aaacgtacca gctgaaggtg gcgacgcacc aatgatctca tggttagccg tattattacc
      301 agttttaggg gtcgttcttt tagatcttca aatcatctta ggttttattc tagcaggtat
      361 ctgggcattg ctgtttactg gaaaattgcg cggaggttat aaagaaatct gtcgtcagtt
      421 tgcgaaatta tttacagatg gcgcagtcga tgttgcacca atggttggtt tcttgatgac
      481 cttagcgatg ttcaataatt cagctgcgta tgcttctcct tatttttcag ctatttttgg
      541 agattggata ccgcaatcac cattagtctt ggcaatcgta tttgctatat tgacaccact
      601 aggatttttc cgcggtccaa tgaatctagt cggttcaggc tcagctattt tagctgtcgt
      661 gttagctgtt aatccaacga tgtcgccagc ctttttgttc ccgttatttg caattacaac
      721 gattgctcct cagcatttag atattacaca atcttgggtt gcttggggat taggttatac
      781 aaaagtaact tctcgagaat atatgaagaa atccatccca actggttgga tcatcggtgc
      841 gatcttatgc ctgatcacgt tcttattgta cgggaacgcc tagtaaacaa aacgtcgata
      901 aaaacgatta gataaatgga ggaaaagaaa atgaaacgtt ttgtgcgaat gggaattgat
      961 gttggcggta cacatacgaa agcagtcgca atcgataatg cgacgcacga aatcatcgga
     1021 aaatcttcag tgaaaacaac ccacgatgat gtccgtggag tagctgcagg tgtcgttcag
     1081 tcttttcaaa attgtttgcg ggaaaataat atcagtccag aagatgttgt gtttgttgca
     1141 cattctacca cacaagcgac taatgcactg attgaaggag acgtagcaaa agtcggcgta
     1201 atcgggatgg caaaaggtgg attagaaggt tttttagcaa aacgacaaac tagattgaac
     1261 gatatcgatt tagggaataa gaaaaaaata gagattgtca atgcattctt acctgtcaaa
     1321 aacttaaatg tagaccgtgt ttcagaaacg atttcttctt tagaaagaga aagagcggag
     1381 gtcttggttt cttctatggc atttggagta gataatgggg aaccagaacg agttgtttat
     1441 gaagcagcat ctgtgaaagc gatccctaca acgatggctt ctgacatcac aaaattatat
     1501 ggattgacaa gaagaactcg gacagcagca atcaacgcat ctattttacc aaaaatgcta
     1561 gatacggcaa cctcgacaga agactccgta cgagaagcag gggtcaatgt ttctttgatg
     1621 attatgcgcg gagacggcgg agtaatggaa atcaatgaaa tgaaaaaacg acctgtttta
     1681 accatgcttt ccggtcctgc tgcatcagtc atgggctctt tgatgtactt gagagcgtct
     1741 aatggtgttt attttgaagt aggcggaaca acaaccaata tcggggtcat taaaaatgga
     1801 cgtccagcaa tcgattattc aattgtaggt ggccacccaa catatatctc ttcattagat
     1861 gttcgggttc taggtgtggc aggcggttcg atggtacggg ctaatcagtc aggaatcatc
     1921 gatgtcggtc cacgttctgc acatattgcc ggtctagatt atgcagtatt tacggagaca
     1981 gaaaaaatca aaggtcctaa ggttgaattt ttctctccta aagaaggaga ccctgctgat
     2041 tacgtcaagg tagtgatgga agacggagaa gaagtgacta ttacaaatac atgtgcagcc
     2101 aatgttcttg gattagtgca agaagaacat ttttcttatg gaaatgtccc atctgcacga
     2161 aaagccatac aggcattagc agactattgt catacgacgg ttgaagacat cgcagagcag
     2221 atcatggaaa aatcctatgc taagattgaa ccggtgattt tagaattggc agacaagtat
     2281 cacttggaga aagatcagat ttctcttgta ggtgtagggg gcggcgctgc ctcattgatt
     2341 acttacttta gtaataaaat gggtgtgaaa tattcgattc ctgaaaacgc cgaagtgatt
     2401 tcttctattg gtgtagcact tgcaatggtc cgagatgttg tagaacgtat catcccttcg
     2461 ccaagtaaag aagatatacg atcgttgaaa aatgaagcga tgaataaagc gattgaatca
     2521 ggcgctacac cagaatcgat cgaagtccac gtagaaatcg atccacatac ttcaaaagta
     2581 acggctatcg ctactggttc tacggaagtg aaagcaaccg atctaaccaa ggagatcaca
     2641 acagaagaag cactagagct tgctgcagag gatatgcgat taaataaaaa tgaagtttgc
     2701 ttattggaaa atacaccttt cttttatgta tgcggcgaac agaatcgttc aaaaaatgct
     2761 ggaagtcttc ggatcatcga tcaaaaagga tttatcaagg tccaacgtgg acatgcttca
     2821 tgtatgaaaa caactgcagc caattatatg acagctgtcg aacaactttg ggaagatatg
     2881 gcagtttatc aaactgaatt gattgcccga ccagaatttt atctctgctt aggagcaaga
     2941 gtctctgatt ttacagcgac ggatctggaa caactacagc ttttgatgga tctggaagta
     3001 tctactatgg aaccggagga agaagtgatc gtcgttgccg gaaatatcaa acaaacataa
     3061 gttagaagag ttactaaacg aattacaaca gatccccgaa gaaatttggg gattctacca
     3121 gtttcggcga gatttatttt ggaaaaagat tcctttgtcc aagcagaaaa ttcttataca
     3181 acaatcaatc gattgtggta tcgaaacggc atgtagcatc aaaaaaaagt acccttttgc
     3241 cgatgtagga gaaatctgtg aacaaatggc tgttccaatc gtttcctgtg aatcagagca
     3301 aataaacgaa cgaatcactt ttgcaactta tgcagaagat gaagggatcc gattgatgac
     3361 ggagccgtta gaaaaattaa aatgttcagg actagcttcg atctctaaag aaacagcgca
     3421 agctttgatt attggacatg aactatttca ccacatcgaa gcttctgtta agggaattta
     3481 tacgcaaagc gaaaaaattg tgctgtggcg gttgcctttt tatacacatc aatcaaacat
     3541 tcgtgcattg agcgagatag cagcgatgag tttttcaaaa gagatgaatc aaagcgattt
     3601 ttcgccttat gtattagagg cagtcttact ttggccatat aatgaaattc gtagccaagg
     3661 gatcttagaa gaaataaaag aaatagaaaa aagatgtacg gagtatgatt tagattacaa
     3721 ataaagagac tgtgacaaaa gtcgtgtcac agtccttttt ttccgaataa acgatgttct
     3781 cctgtcaact cctcggtcac aagtcaaaat attcaacaaa catgagaagc tgttttttga
     3841 aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttgga aaacggtgtt
     3901 caaaagcttg catctgcggt aataagaaca gccaagttaa aaacataaga agctattttt
     3961 acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctc aataaacggt
     4021 gtgcaatcag ctgaccctcg gtattagctc aaaaaaaacg gcaaaatatg aggaactatt
     4081 ttgccgttta tttctctaat actcaggtca aaacgctgat tccaaaacct cttatttgat
     4141 gggtctgtcc tgaatatctt caaaataatc ggggtaatta tgaatcacgt attcttgctc
     4201 ctcgataatc atatgtaaat gcatcgtgca aagaaatccg acttcatcaa agttatgatc
     4261 aatcattgat tgaagcattg tctgatgttc atctaatact cgaccccagt ctaattctga
     4321 aatcgtcaaa cgtaaccatc tgaaacggtt caagtgcgta ctataacttt ctagccaatc
     4381 ccaaatttct cgttttccag caatttcata acaagttcgg tgaaaatcag tatccaaatc
     4441 aaaaaaagct tttttatttt gagcgattac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccaggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgatctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt ccccgtatac ttttggatag
     5401 ttggatggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccatttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aatagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcccgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcagcaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaaactaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccgct gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaattttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcta aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ctcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataattaatt aaaaagagga tcaagaattg caaattattt ttgcagtctt
     8101 gatccttttt ttactttcta ctgtggtatt catgataaac atgatataga ttcaattcat
     8161 attctttctt agcgttcgtg acgactgtat ccaaaatcaa ccctgttact aatgaaagaa
     8221 gtgctaaagt catcaatcca gtacttaaaa tcgcagaagg gatgcgtgta ataaagcttg
     8281 tcagcatata ttcgcgaatc acaggaatcc ccgtgaccaa tccaaataaa aagaagaaaa
     8341 tggtccaaat cccaaagaaa agcaaaggct tataatcttt aaacatttta ataatcatca
     8401 tgatcacttt gaatccgtca gagaatgtat tcaattttga ttcgctgcct tcaggacgat
     8461 cacgataatc gattgggatt tcaacgaact tgaatttttt atctaaagca tggatcgtca
     8521 attccgtttc gatttgaaaa ccagaactca taataggaaa acttttgaca aagatacgat
     8581 tgaatcctcg atagccggtc atgacatcaa gaatttttgt tttatacatt ctagtaattg
     8641 tatttctaac aaggttattt ccaaaatcgt ggaaaggtct cttattctca tcaaagtagg
     8701 ttccatttga taggcgatca ccaatgacca tatctgcttc accagaacgt aatttctcga
     8761 gcaaaccatg tacagcttct gcaggataag tatcatcgcc atctaccatt aaataatagt
     8821 cggcatcgat atcaaagaac atttggcgga tcacatttcc ttttccttga cgaggttctt
     8881 tttttacgat tgctccacct tgaacggcca attcgtatgt tcgatcggtc gaattattat
     8941 catagacata aatatctgct tctggtaatt ctcgtttaaa gtctgcaatg actgttgaaa
     9001 ttgttgcttc ctcattgtaa caaggaatca gaacagcaat tttttcttgt tgttccattt
     9061 ttcactctcc ttaactatag aaaacaaaag ctaaattaaa aatacctcat aatcaaagga
     9121 aatgctagtt tttcccgcta aatatcattt atttaaaaag aaaatactgg aatatatgtt
     9181 tggaaagctc tatctaaaaa accacccact acaaaagaag gacatgatac ctctcttttg
     9241 aatagtgggt gcgtattcgt tctctcactt ttttgacgta ttaatctgtt gcaccttttt
     9301 ttcttgaaat ttctaatacg gttcctgtat gagcatctgc taaaaattca taataaacag
     9361 tttcgccatc ttctattcga gaaagacctc cccgataagc actcgaccga acggcgaatt
     9421 tcctaatagg ttccttttca aaagagatcc aagaaccttc gattgcacct tcttttagaa
     9481 aagatgactt gatattttca agtacttggt ctgctgacaa tacttttttg cgatgatacc
     9541 aaatcgttga agctaccccg ctcaataatc ctagaccgat tccaactgct aacccgcctt
     9601 taaaatagct tagttcgctt tcttcataca tgtggacata cctccttctt ctcacttgtt
     9661 actccttgtg cttattttac cacactctca tattttcttt gaaataaata accgctacca
     9721 gaaaaaataa gctataataa atacgatcgg tctgcagaaa aaatcatatt ttatccgcag
     9781 atcaatataa gtctgagagg agtttagtct gaaatttaga cgaatagcat atggaagaaa
     9841 aaacatttca acgaatcaaa gagttaacag aattacaagg aacaagcggt tttgaacaag
     9901 atgttcgcgc ttatatggaa agtcatatgg aaccgctggt agatgagtta cagttagatg
     9961 gtttgggcgg catttttggt ctgcgccatc atgaagaagc ggatgcaccc cgtgtaatgg
    10021 tcgcagcaca tatggatgaa gtcggattca tgctgacaca aatccaagaa aacgggcttt
    10081 ttaaagtcgt acctctaggc ggctggaatc cttacgttgt ttctgctcag cgttttacac
    10141 ttaaaacctc tactggtaag aattatccat gtatttcttc ttccgttccc ccacatttat
    10201 tgcgaggaac aagcggacaa aaatcagtag aagtaaccga tattttgttc gatgctgggt
    10261 ttgaatcaag agaagaggca atgagttacg gtgtccttcc aggagacaca atcgttcctt
    10321 acgctgaaac gatcaaaaca gccaacggaa agaatattat cagtaaatca tgggacaacc
    10381 gctatggctg tacaatggta ttagaagctt tagaagcgtt gcaaaatgaa acattaggtc
    10441 atacattgat tgcaggcgcg aatgtccagg aagaagtagg cttgcgtggt tctaaagctt
    10501 ctgtcaataa attcaagcca gatctgttct ttgcagtaga ctgctctgca gcagatgata
    10561 cagtgacgaa aaatggcaca ttcggacatt taggagaagg tacattgatg cgtatccaag
    10621 atccaggttt gatcatgctt cctcgtttgc gcgagtactt gctggatatc gctgaaacaa
    10681 acaatatccc ttatcaatac tttgtttcaa aaggcggtac agatgcaggt gctgctcata
    10741 cacaaaacga aggaatccca agtacagtga ttggcgtagt gggacgttat atccatacgc
    10801 atcaaacgat gttcagtatt cgcgattttg aagctgcacg agaaatgttg attcaaacac
    10861 tgaaaggttt ggataaatca acagtaaata cgatcgtata cggaaaataa tgcgatagtg
    10921 aaactataaa atctggcaaa agattgcttt ttgccagatt ttttttataa aaagaggatc
    10981 aatgtttgtt agttcgaaag aaaggtgtat aatttaattg aaaaatacat aaacagaaag
    11041 tagaggacaa agaatgatta tcccaaatag tttagaagaa ttagcaggct acgtagaaac
    11101 tggaaagagt gtatttttct ttactgccgg ctggtgcgga gactgccgtt ttatcaaacc
    11161 gcaaatgcct gaaattgaaa atgacttttc tgattggcaa tttattgaag tagaccgtga
    11221 caagtacata gatgtagccg ctgaatggaa catttttggt atcccaagtt ttgtcgtgat
    11281 ccaagacgga aaagaattag gtcgtctagt gaataaagat cgtaaaacaa aacaggaaat
    11341 cgaatcgttc ctagaaagtg taacaaaagg ctgacatctg ttaggagggg tcaagatgaa
    11401 tcaagaatat aagaatattt tagtaggtat cgacggtagt gaacaagcac ttgctgcttt
    11461 caaaaaagcg gtagaagtgg ctcgccgtaa taatgggaaa gtatatgtag caaacgtaat
    11521 cgatcagcaa ttttataact ttatgggcta tgcacctatt gatcaaaatc tagtcgatca
    11581 gcaaactgaa acagccaagg aaatgatcga agaatgtaaa gaatatggga aatctgttga
    11641 ttacacaaat atagaaggaa ttattgcata tggttctgtt cgtgaatcca tggcagtcaa
    11701 attgccaaaa aaatatgaga tcgatctaat catggttggg cagtcaggtc taaatgcagt
    11761 cgaacgcttt atgacaggaa gtgtagccag ctacgtgata cgtcattcac cttgtgatgt
    11821 cttgatcgtt tctgacgaag aagaacagcc aagtaattaa gcaagtggaa cttgtacgac
    11881 ctttttaatc aattaactaa aacagtaaag ggactgtgac aaaagtcttg tcacagtccc
    11941 ttgttacgaa taaatggtgt tccagaagag gcttcttcgg aaataaagca tgaaaaaaat
    12001 ttcatgcagt gaatgcaatt ttttgttaag ataaatctca gcaaaggata atggaggaaa
    12061 gaacatgatt tttgcttata acaaagcaca cgtcggagac accttgatgg ttattatagc
    12121 cgacgataaa ggaacagaaa acactgttga acgcaaatgg aatgttgctc ggatcaaaga
    12181 tgaacaaggt caagttgttg cttggaactt tttccatatc tccgatcatc taacaatcga
    12241 agggaacggc caagtaagct taacagatga ggaattagcg aaattgaatc gattgatcaa
    12301 agaagcagga ttcgaagaac agcttgaagc tgatcatgaa ccgaagatcg ttgtcgggta
    12361 cgtaaaaaca tgcgtcccac atcctgattc tgaccattta tcgattactg agacagaagt
    12421 agacaatggt acagtattgc aaatcgtttg cggtgcaccc aatatcgaag ctggacaaaa
    12481 agttgtcgtt gcaaaaccag gagctatgat gccagatgga atgatgatct ggccaggaac
    12541 tttgcgaggg gtagatagct atggaatgat ctgttccgct cgtgaattgc atttgccaaa
    12601 tgctccagca aaaaaaggaa tcttagtatt gcctgaggat gccgtagtcg gagaagcatt
    12661 tccaaaataa agaggttgtg acaagtcttt gtcacaacct cttttttatt aattttcact
    12721 attttgattt tgttttaatg ccgattgatc gatcgtcaat tcaacagtag ttgttttttc
    12781 tttcgagcct tcatagtaag tgattttgac agaatctccc acttttttct tatacaaagc
    12841 agattgaagt tctacaccag aagaaacttc tttgtcatcg atcttagtaa tgacgtcgta
    12901 ttgtttcaat ccagcttttt cagccggtgt agctgtttgg acatttgtca cgatgacacc
    12961 gttagttaca gatgaaggaa tcttcaagat ttgttcttgt tgctgagtag aaacggcaga
    13021 taagtcgacc attgtgatac ctagagctgg acgtgtcact tttccgtctt tttccagttg
    13081 attgatgata ttcactacat cgttacttgg aatagcaaat cccattcctt ctacgcttac
    13141 attagaagta gattcagaag tacttgcgat cttacttgag ttgataccga taacttgtcc
    13201 ttcgatatta actaaaggac caccagaatt tccagggttg attgctgcat ctgtttggat
    13261 cgcattgata ttgactgttt cgttcgattc attcgtactt gtcacttgtc ggttcaagga
    13321 agaaatgatt cctgaagtga cagaatttgc atattcagat cctagtgggg aaccaatcgc
    13381 aatcgcaggc tcaccaacct tcagagcact tgagtcacca aaagaggcaa ctgtttcgac
    13441 tttgtctgaa ttgatcttca acaccgctaa atctgaataa gcatctgttc caactaattc
    13501 agcttttacc ttcgtaccgt ctttcatcaa gacttcaaga ccttgctggc catctactac
    13561 gtgattattc gtgactacat aagcagtatt cccgtctttt ttgtagatca cgccgcttcc
    13621 ttcactataa gcttccaaat tactatcatc tgagctgcta ctttcttctt gctgcccgaa
    13681 tagtccgcca aaaccgcttg attggttttg actttgtaag ttgataacag aaacgacagc
    13741 gtcttgaact ttatctaccg ctttggtgat atcagaatct acattgactt tgacattttc
    13801 cacaactgtt tcaccggcag aattctgatt gccgcttgta gcagtagaac tattgttgcc
    13861 agtgcccatc gctgcataaa aaatgccagc tgtcagtagt cctccaacga tccctccaac
    13921 aagccccaga cctaacttac gccagaggct attattttta ctttttttca tctttggtgt
    13981 cacatttttt ctatccatgt gttcctcctc caattacatt catttatcta ctgttagtat
    14041 agtcttattt gttgacttta gtctactttg agactgtgaa ctttttatga aaaactttag
    14101 gaaaaatcat tgttttcaga tgaaaatatt tgattttctt tttccacaga tactgtgtaa
    14161 aactacgcgg ataggattgg aaaaataagg gataaaacat atccacagcc tgtgtataaa
    14221 gtggataaat tcttataaaa cgtatgtttg cctaatgaat gtgatgaaat aaggtaaaat
    14281 aacactgttt tctgtggata aacctgtgga tgttgtgcat aactgttggg gaaatctttt
    14341 taacaaaaat agccaaaata aacatataga cgaaaaaatt gattataata aacaaagtga
    14401 gcatgaagac caaaggagag aaaacatgaa tatcaaaatt atctcagtag gaaaattaaa
    14461 agaaaaatac ctgatccaag gtatcaatga gtatgtcaaa cggctgaatg cctatgcaaa
    14521 aatcgaattg atcgaagttc ctgacgaaaa agccccggag aatttaagcg aagcgcaaat
    14581 gagacaagta aaagaaaaag aaggggaacg gatcttagcg aaaatcaaag aacaagaata
    14641 cgtctatgcc ttagcaattg aagggaaaaa tcctacaagt gaatcttttg ctaaacaaat
    14701 cgaccaatta ggtatccaag gaaaaagcca ccttgttttt gttatcggcg gctctttagg
    14761 actcagcgaa gccgtcatga aaagaagcaa tgctcagatc tcttttggaa aaatgacgta
    14821 tccacatcaa ttgatgcgtc tgatccttgt cgagcaaatc taccgtgcct tccggatcaa
    14881 tgcgggggct ccataccaca aataatgata ttttttaaga gaaaaaatta tccctatttt
    14941 aaataatagc aataggtagt ggtagggaga aatttataaa taactttttt atttgctttg
    15001 gtagccaagt aagttgcaaa agaaaaatag atactgttaa aaagataatg tagacataga
    15061 aacaaatacg taaaatttta gttagaataa tggcaaggag aaaaaacatg atagatgaaa
    15121 aaaagtgttt aaaaaatcta ttagaggata tggatgatat tgaagaaaac tatctaaatg
    15181 gactgggaaa acaaatatat ttcagatact taagctatct aaaaatgaaa taagacatag
    15241 taatttttta gcttttttgt ttgctccaaa tgaaacccac aatttatctg atgagttttt
    15301 taaaatgttt ttgaaaaggt atatagattc taatgatgat accaaagctg ctatcaatta
    15361 ttttgatgct ttacttaata gctatgaaga tttaattgtt tacagagaaa ataagaatat
    15421 tgatatttta ttggtatcgg aaaaaaataa aatagtggtg tgcatcgaaa ataaaattct
    15481 gtcttcggag tctggagggc aacttaataa ataccaaata tatatagaac gcaattattc
    15541 taactataaa aaaatttttg tttttttaac tccagatgga aatgaaccca caaatcctag
    15601 ttggggcata attacttaca agaatatcgt tgaagagagt gtaaaatatt ttgtgtaaat
    15661 agaaaaaagg aagtcccttc tgtagaatag agttaccaca acacattcac agaaaagagg
    15721 acttccatat gaacgatttt actacagaaa ttatggaaat actaatcaat aaaggtgatt
    15781 tggatgattt gtttcgtcgt cacctagaat tggctattaa cgctttatta caagctgaat
    15841 taacggtatt tcttgactat gaaaagtatg atagagctgg atttaattca ggtaattccc
    15901 gtaatgggaa ttattcgcgc tcttttaaaa cagagtacgg tgaattgaat ttagtaatac
    15961 ctagagatag gaatggagac ttttctcaac aaactttacc tgcttataaa agaaccaatg
    16021 actctttaga aaccactatt attcagctag ttcaaaaagg aattactatg tccgaaatct
    16081 ctgatctaat cgaaaaaatg tatggtcatt attacaaacc acaaactatt tcaaatatga
    16141 gtaaaattgt gtctgaagat gtttcggcat ttaaagaaag aactttagaa gctaaatact
    16201 cagtcatttt tatggatgct actcatattc ccttaaaaag acaaaccgta tcaaaagaag
    16261 ctgtctatat agtaattggt atcaggttgg atggaactaa agaggttcta ggatttacta
    16321 tagctccaac tgaatctgct tatgtttgga aagagattct tcaagatcta aaagaccgtg
    16381 gtttagaaga ggttttgtta gtcgtaacag atggtttaag tggtattgac gatagtattc
    16441 atagtgttta tccaaatgct caatttcaac aatgttgtgt ccatatatct agaaatatcg
    16501 ctcataaggt tcgtgttagt gatcgacaag aaatctgtag cgatttcaaa ttagtttacc
    16561 aagcaagttc aaaagaagaa gcaaataatc aaataaggtt tatgatagat aaatggaaaa
    16621 agcagtatcc acgagtggtt aaattgctca tgaatcctgc tatattaacc ttttataatt
    16681 tccctccgtc aatcagaaga actatttatt caactaattt gattgaaggt tttaacaaac
    16741 aattaaagaa atataccaaa agaaaagagc aatttcctaa tgaagaatct ctggagagat
    16801 ttctagtatc tcaattcaac aactataatc aaaagtttct atgccgagtt cataaaggtt
    16861 ttaaagaaat acatgataca ttagaatcaa tgttttaact tgatcaacag aatgggcttt
    16921 tccatttaca cataattatt gacacaacct attctctgga aacttacaaa taaaagctta
    16981 ttcttcagcc accttcgggt ggttattttt tataaaaaaa tgtaaaaaaa tattgataca
    17041 taaataaatt agttgtagta aatagtttta gaattgaatt tctctatcct ttttaaataa
    17101 ttttttagac aaaaaacaga aagtgtctaa agaaagcttg acgaagaaaa taatttttaa
    17161 taacttattt aaggaaattt tttgaaggag aagataaaag tgagaaaaaa gattattatt
    17221 aatgctggag taattatagg attgatgtta gtaattttct ccggaaagca atatgctgat
    17281 aatattttat tatggggagg ggaagataat attgaaaaga tcaacaacaa tttaactata
    17341 ttagacacag ctctagaaaa taaagagcaa aaaattagta ttttaaattc acaattgtct
    17401 tcaaacaacc aaactcttga acaactaaga actaatattg aagtttccaa acaaaaagtg
    17461 gcatctttag aaaacgacaa gaatcaatta gtatcagaga aaactaattt agaaaatcaa
    17521 ttgtcagcaa aagactctga attgcaagga aaacaaaatg aaattaatgc gaaaatagac
    17581 gaaattaacc aaaaagtagc tgaaataaat cgattaaata gcgattggaa taatcgttta
    17641 caaaatgaaa agaacaaatt taatgaagaa caatctacta ttaatagttt aaaccagcaa
    17701 attaatcaaa tgttgagtga aaaaaataac attcaaaatc aactgcaagc tactcagcaa
    17761 aagctagaag aagaaaagtc aaaaaatagt agtttgaata attacattga aaagcttcaa
    17821 aaagctaaaa atgatgtaga ggataccgca aataaagcac aacaaattgt aaatgaacat
    17881 acaatccaat agatatagtt ttaatttaac aaatggtatg tttggagata atgagataga
    17941 atataaatgt cataatatta tacaatctaa acaccgtttc cttttctatt tttgatgaca
    18001 tcagtatata gctactcgaa agagtagtct ttttattatt ctcgcttatt attgatatga
    18061 aaatttcgat ttgacaaaag gtaccgaata attttgtaat atgaattatt atcaagaagt
    18121 aattatgatg ataacatatg gaaactagtt agtaataata acaggtgatt aaacttttga
    18181 acgacttgta attctatatt ttttctttta agtaaaaaat ataggtgatt ttttttgact
    18241 tcatatttat aataaagaca cgtaaatcaa ttatttttca ttttacttta actaataatg
    18301 tttatttgga gggattatta tgttagatga tagattgacg tgttctaatt gtggtacatt
    18361 attttactat gaggaagtta gaaatattgt aaaacataga aaaaaagaaa tgcctatacg
    18421 ttgtccaaat tgcaatgaag ttattaagcg aaagttgtct catggttatt ttgtcagcta
    18481 cgaactatat gaagaaagta aaataaatct gaaaaaaaaa ccaaaatact ataaaaattt
    18541 gaaaactgga gctattataa ctgaaaaaga atttaaaaat ttagtgactg aagaagaaag
    18601 caggttttat aatttgtctg gtaatatttg ccctggattt atggatcaga ttattgaaaa
    18661 tgagtcaatt gaatcaattg aaaactatgt tcctgttgac ttaccaaaat agaaaaaata
    18721 atcctgtttt tacagtgaat tattttaatt ttgattttca ataaaaatat attacaataa
    18781 taatcgtaat agctaatgaa acaatttctc aatcttttta ccactccaaa cagggagcgt
    18841 caataatttt gtgtaaataa ctcgtccttc tgcaaaataa tgggttactc agtaaacatt
    18901 gaagctaatg tatccgtcac ttgttggaag cctttatggc ttctatttaa gaatttttga
    18961 ttgtatgtat caaagatgga tactaggaaa cgctctagtg attcttcatt ttgaaactgc
    19021 tcttttctgc ggctgtattt cttgatttgt ttattgaaag attcgattgt agaaccagaa
    19081 ggaatggaga acacttttga actttacaac aaaactactg ttgataaatt aattccaatt
    19141 ttagttccaa ctgatttaaa tggtcatgat gttttacttc gttttaacgg atttttaggt
    19201 gaggattata gatacctaaa aatttctgat cctcaacctt taacagaata ataaaaaa
//
LOCUS       DAFEML010000044        18895 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFEML010000044
VERSION     DAFEML010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.045"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(21..251)
                     /locus_tag="LP468_001864"
     CDS             complement(21..251)
                     /locus_tag="LP468_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081381.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LP468_001865"
     CDS             complement(687..1253)
                     /locus_tag="LP468_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2081382.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LP468_001866"
     CDS             complement(1253..2209)
                     /locus_tag="LP468_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL2081383.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LP468_001867"
     CDS             complement(2209..2865)
                     /locus_tag="LP468_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2081384.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LP468_001868"
     CDS             3235..5253
                     /locus_tag="LP468_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2081385.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTFEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LP468_001869"
     CDS             5680..8094
                     /locus_tag="LP468_001869"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL2081386.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LP468_001870"
     CDS             8442..9995
                     /locus_tag="LP468_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2081387.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LP468_001871"
     CDS             complement(10376..12160)
                     /locus_tag="LP468_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081388.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LP468_001872"
     CDS             complement(12175..13896)
                     /locus_tag="LP468_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081389.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LP468_001873"
     CDS             13996..14757
                     /locus_tag="LP468_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2081390.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LP468_001874"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LP468_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18895
                     /locus_tag="LP468_001875"
     CDS             16664..>18895
                     /locus_tag="LP468_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081391.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3352 c         3786 g         5552 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgtttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DAFEML010000045        18366 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFEML010000045
VERSION     DAFEML010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.046"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            159..1052
                     /locus_tag="LP468_001876"
     CDS             159..1052
                     /locus_tag="LP468_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL2081392.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            1186..1311
                     /locus_tag="LP468_001877"
     CDS             1186..1311
                     /locus_tag="LP468_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081393.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1445..2077)
                     /locus_tag="LP468_001878"
     CDS             complement(1445..2077)
                     /locus_tag="LP468_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081394.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(2225..2767)
                     /locus_tag="LP468_001879"
     CDS             complement(2225..2767)
                     /locus_tag="LP468_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL2081395.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            2901..3290
                     /locus_tag="LP468_001880"
     CDS             2901..3290
                     /locus_tag="LP468_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081396.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3294..4058
                     /locus_tag="LP468_001881"
     CDS             3294..4058
                     /locus_tag="LP468_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2081397.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            4187..5134
                     /locus_tag="LP468_001882"
     CDS             4187..5134
                     /locus_tag="LP468_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2081398.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            5264..6004
                     /locus_tag="LP468_001883"
     CDS             5264..6004
                     /locus_tag="LP468_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081399.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(6295..6963)
                     /locus_tag="LP468_001884"
     CDS             complement(6295..6963)
                     /locus_tag="LP468_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2081400.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            7097..7384
                     /locus_tag="LP468_001885"
     CDS             7097..7384
                     /locus_tag="LP468_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081401.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            7800..9338
                     /locus_tag="LP468_001886"
     CDS             7800..9338
                     /locus_tag="LP468_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL2081402.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            9335..10300
                     /locus_tag="LP468_001887"
     CDS             9335..10300
                     /locus_tag="LP468_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081403.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            10287..11609
                     /locus_tag="LP468_001888"
     CDS             10287..11609
                     /locus_tag="LP468_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2081404.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      11672..11776
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11850..12593
                     /locus_tag="LP468_001889"
     CDS             11850..12593
                     /locus_tag="LP468_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081405.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            12608..13600
                     /locus_tag="LP468_001890"
     CDS             12608..13600
                     /locus_tag="LP468_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2081406.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            13612..14349
                     /locus_tag="LP468_001891"
     CDS             13612..14349
                     /locus_tag="LP468_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081407.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            14339..15061
                     /locus_tag="LP468_001892"
     CDS             14339..15061
                     /locus_tag="LP468_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2081408.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(15145..15768)
                     /locus_tag="LP468_001893"
     CDS             complement(15145..15768)
                     /locus_tag="LP468_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2081409.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            16163..16854
                     /locus_tag="LP468_001894"
                     /pseudo
     CDS             16163..16854
                     /locus_tag="LP468_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            17062..17352
                     /locus_tag="LP468_001895"
     CDS             17062..17352
                     /locus_tag="LP468_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081410.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         6296 a         3012 c         3702 g         5356 t
ORIGIN      
        1 tctaaaggat ttcaaggtgt cttttctata tgttttggaa aataaaaaag atgctggtgt
       61 catccaccaa catcaaaaag tatagagcct cttgttcttc ctccttttta cgtaaaagcc
      121 ttttaagtaa aataaaacgg atagaaaaga gaacatatat gaactattat tcaaaaaata
      181 aggaaaactt ttatcaaaaa ctgaccgatg atccgctttt ttcttcattg accgattatc
      241 tatatgaaca tcgagaacaa gaaacgattc taagagaatt gaaaaaagaa ttttcgcaaa
      301 ataaattttc ccattttctt gatttattga tcgatgcagg attaatcaag agggaagaac
      361 gaagatatca tttgaacttt ccaatatttg atcctaaaga ttacttgcaa caagccactt
      421 cggctgctga aaccatagct gaacaattga agagactctc tgttgatgaa caaaaattag
      481 cgatgggaga agttatttgg gcgtattgtt tcgaagatga acggaaagaa gcgtattttt
      541 atggagtaag aaacagccga gagacagaat tgctgaggac aactgcagga aatgagaagt
      601 accgttttat cacactttcc tctatagaac acttcccgct tactttggct aattactttt
      661 ttgtacagaa gaatcagctt cctgtaacga aggcattcaa agaattagcc gaacttattg
      721 gagacgtaaa tgaatcgtac ttttttgatc aaatagaagt tatcgttgac aggatacgta
      781 agaataaata taaaaatcgc cggcctagta ttttccatca gtctctactt gtgacgaata
      841 ctataaagga agaagaatca ttcacattag aattacctat tgtcgaaaaa aacaattttg
      901 agattgaatt accaacattg gatccttcat tgacaatgga ggaaatggcc tttcttaaac
      961 gacaaatctt ttctgagctg agcaagaaat ttataccgca tgcattttct tatatcaaag
     1021 aatatggaac agttttagtg agtaaaacct aagagagcag taagcaaaaa ttatactgac
     1081 tcttgcagga ggagcctttc tcttccttta tggttaaaag aattatttga gtattttgcc
     1141 tatctaccac ctattagatt cactacatgg tctggaaaca aaggaatgca aaaaaatggt
     1201 gagaaatgtg gaatgacaaa ggaagtagtg ataagaaaag ttagattttt aaataatcaa
     1261 tattatgatt cagtcaagta tggcatttta tgggaagaac tagctgatta gattaggaag
     1321 tccatttgat aatccagaat cactaagaaa cgaatggcga gtcattaata atttatccaa
     1381 tcttgggtta ttcttttaga ttgaagtgtt taaaactaaa aaagcattta tgaagtcgta
     1441 atagtcaggc ttcaaaatgc tttttatttt gtttgttttt tctttgccac ataaatacac
     1501 ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc gtcgaagggt
     1561 tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata aaacaggtga
     1621 caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt gaaaaaataa
     1681 aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag aaaagcgtat
     1741 tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat gcaatcaata
     1801 cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca ccgaaataaa
     1861 cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt tcttcggctt
     1921 ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc gcatgtgagg
     1981 tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa aaagagccta
     2041 aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat taaattgata
     2101 agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta atcaaaataa
     2161 taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt tttaagtttg
     2221 tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct gaaatatatt
     2281 ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg cgatacagtt
     2341 cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct tccagcccca
     2401 ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc aaacttttat
     2461 cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat gccaatttgt
     2521 cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag acaaataaat
     2581 tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa atcgtgatct
     2641 cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac atgaaacgta
     2701 acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac atttttggat
     2761 caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa atcgtaagtg
     2821 aagaaaaatt gaaactttat acatacaaaa aatgataaaa tgattataat agaattataa
     2881 agataggtta ggtgattaaa atgaaaacgg tcaatcgtgt gttttgtgcc agccacgtgc
     2941 taagtctcct tctcagtata tacttaggtg tctattcgat tcaacagcca attgaggtag
     3001 agaacattgt ttttcagatg tcgctgacag atggtttaat tttaagcgtt tttttctttt
     3061 tgatactgtt tattggtaat attttcggta gcgttgccag ttttttgaat ttttctattt
     3121 atccactcct ttcgctagca ttaggagtgg tgggactttg ttctctgtgc ttatttcccg
     3181 agccattcag tcctgcattt atattatttg gtacactgaa cctgttccag acaactgttg
     3241 gagcatggtt gctatggcga tcaggaaatt taatgaaaat aggtgagtaa caattgaatc
     3301 caattatatt gaaacgttct gtccatcata ttccagtgtt agaagttgtt ctgaaagaat
     3361 taagagagga acgtattccc gttgtcatct attatcacgg atggcagaca agtaaggagt
     3421 tagttttgac gcaaggaaga aaaattgcgc agcagggcat tcgtgtgatc ctgccagatg
     3481 cgatgaatca tggggagcgc aaacagccgg tttcttctat tccatcctat acattttggg
     3541 atagtatcta cggaaatctg tttgaatttg acacacttat caagcattta gaaaaaagag
     3601 gtcttctaca tgatcagctt gcagttggcg gggtttcgat ggggggaatg acaacatgcg
     3661 ccttgttggc taaacatcct catatagtag cgggcgtgtg tttgatgggt tcccctgcac
     3721 ctttggaata tggaaaagaa atcgtaaggc gcgcatcgga atataattat gtcgtaccaa
     3781 aagactattt tgatttgatt tcatgggtta agagctatga tttgtcattg cagccggaaa
     3841 agttagctgg acgtcctctg ttcttttggc atggacaagc tgacgaaaaa atcccttata
     3901 tacaaacgga acgatttgta gaaaaaaatc ggcataagtc ttacggaaaa gaaattgttt
     3961 ttcgttcctc aaaaacacag cgacatatgg tacaaatacc actaatggaa gaagcttcca
     4021 cttttttagc aaaaaatttg ataaaaaagt ataaataatt gaaacggaaa atcactcatg
     4081 acgatagagg attttccgtt ttttattttg ggctataata aactctgtta ggaaaatttg
     4141 gtataattga tagtaagaat gacaacatgt tagaaaggaa gagagcatgc ccactttagc
     4201 agatgttgca aaacgtgcca atgtttcaaa aatgacggtc tctcgagtca tcaatcatcc
     4261 ggaacaggtg actgacgaat tgaaagagtt agttttctca gcaatggctg aactggatta
     4321 ccgtccaaat attgctgcaa aagcacttgt cacgaatcgg tcgcagatca tcaaattatt
     4381 tatactggaa gaaatcgaca caactgagcc ctattacatg aatttgctga tgggaatcgc
     4441 taaacggatc ggtaaagcgc attattctct ccaattagtt acaaatgatg ccttcgacgt
     4501 cggttcttgt gatggataca tcatcacagg tgtcagaaaa aaagacttcg attggatcga
     4561 ccgtttggaa aaaccagttg tcttgtttgg ggaaaattct gaaggatatg attatgtaga
     4621 cagcgataat gaatatggta cagcaaaagc aacgcaatat gccttagaaa gagattatca
     4681 aacgattatt tatatcggta tcgaagtgga cgagcctttt gaaatttcaa gggaaactgg
     4741 ttatttatct gtgatgaagg aagttgatct tcctagtaaa atcttgcggt ttccaaatca
     4801 ttcgacagaa gtagaaagat atatgacaga aaactgggca gattttacag ataaaacttg
     4861 ttttgtatgt agttcagatc ggctagcact aggagcagta agagggatta taaatgctgg
     4921 aggacacttg cccgaagaat ttggtgtgat tggatttgat ggggtatttt tagaccaaat
     4981 cagttcacct aaattgacaa cgatcaagca agatattata cgtatgggtg aagtatgtgg
     5041 agaaatgttg ttaaaaaaaa tagaagaaaa aggggcgagt caaggttatc gtcgtttttt
     5101 tcctgaacta gttatcagag agacaacgaa ttaagtctta ttactatata tatatttatg
     5161 aaattcatcg ctattttctt aaaataatca gcgcattgct actgaaaaca atgaatctgt
     5221 gctattattg agaaaagttc catttttgag aaggatggtt tgaatgaaag aaatcagacg
     5281 aaaacatttc cgttttcctg cgtacgatga tgagttaggc gtaaaattaa ccaacgacaa
     5341 gaagcgagta ttatttgacg gacaagaaga tcttttgact gaacagaatc agtccccgtt
     5401 tgaacagatg aaagaatttc atttcacgaa cacgaacacc gagaaaatcc gtcgcaagcg
     5461 tcgtgcaaca aatggattga agtcagctcc gcgtaaggaa aatttggaaa agcataaagg
     5521 aaaattaccg gattataccg gccattacca atcagaaatc acatcgacag gacgaaaaaa
     5581 actttttggt gattcctctc gttctgtcag acaaagtgaa acaaggacag agtccaagca
     5641 tactacacga aacgcatctg ttgacacgaa ggtgcgggag cgttcttatt ttgttcctaa
     5701 atatgtaccc gcatcgatta tcccagaccc tagagaaagc aaaatttctg aggatcattt
     5761 aatcgaatcg atgaaaaaaa cggatgactc ttatctgttg ttcgatacag aaccgacgcc
     5821 gtatcaagaa aaaagaaatg gtgagccgtc tgtacgaaca ttcaatcgaa caaaaacgtt
     5881 agaggaaaca aagcagtcag aagaaaaaaa atcgaaaaaa agccatggta tcttagaacg
     5941 ctcattacaa ggattgatcg atgatcaagg aaactctttg ggagaaaata gctattttaa
     6001 ataagtgata tacaaattta tattcggcta cagttggaaa ggaaacgctg cggcgtttcc
     6061 ttattttata ctctatccga aagtttatat cgtatcctca aatttttttg agtttaagcg
     6121 aattttttct cccaataagt aagaaaataa tggcaaaata aaaaaacaaa ctattttcgc
     6181 agatcgtttg caaaaatagt ttattttttt ataaagaaga ttttactgaa taatatcatt
     6241 ttagtttaca taatgatatt tctgtaaatt aaataaagta gtgaaaaata agaatcagtg
     6301 ctctaactgt tcaagaggat caagtggttc aaatgtttct gtagtctgtt ttgcttccaa
     6361 ttggggcaaa acagatccaa tttccagata cttcacttta ttcaatgtat aagatagaat
     6421 agaacagcta agtaatgtat acagaaaatg tgtgagatcc aaataaagca aggagacaac
     6481 taaaatacca aaagtaatca agaaaagact tttgccaatc ttaatatgaa aatatttttc
     6541 aatggcttga taaatgatat ctgttccgcc tgtgcttccg ccgaatcgaa agacgagacc
     6601 gcaaccaatg ccagaaagaa tacctgtcat caaactattg atcagtagac tatctacagc
     6661 aaaatgtata tgaaggctct cccataaatg taaaaagaaa actagcgcaa atgttccgac
     6721 gatcgtccgg agaaaagcgt gttttccaaa aagaaacaat gagataagca ataaaggtaa
     6781 attaaaaagc agtgaagtga cagaaggagc gaatccaaaa agattatgca aaagcaaagc
     6841 aataccagta accccaccat ctgccagctt agatggaata ttgattcctg tcacagctaa
     6901 tccgtagatt cctgcgccta aaatgattcc gcacaattct gtaaataaat ttaatttttt
     6961 catttctagc ctcttttctt ttgaaaattt tcagcaactt ctttattata ctgacttata
     7021 ctcttacttc aagaggaaaa tgaaaaaaaa ttatttttgg ctgtttcttt ttatttatca
     7081 aataaggagt ggaaaaatgc gagcagcaga cttattgaca attcttacaa aatcacccaa
     7141 aaaaacagag tatcaaggag tttttttggc tcaagaacaa aaactggtgc ctgtgacaat
     7201 ggtccagata aataaagcaa atcaatttat ctttttattt gaacacggca aagcaccact
     7261 tgctatgaaa gacatctttc tttttttgat gaagaaccgt gagaaagctg tttattatca
     7321 gtcaaaagaa gaactcattc ctctttatgg agtgaaagag atagaaaata aagtggtgat
     7381 ataagtaaaa ataagaaaac aagacgttta tgatgtcaaa acaaccattt tttacatttt
     7441 tggcaaaaaa gtgtcatgat acagtataat attcgttgaa caggccaata aaggtgttct
     7501 cccccacgag atttctactt tattggctgt ttctttttat taaaataaaa gttgtgtgtg
     7561 taaaaaagat atagctgatt ccaagtgaca atttcgtata gatttttatg gtattcgtag
     7621 tgaaaaaacg agaaccaaaa agttgatccg actttgttgc ttggattctt tttttgtcag
     7681 catatttaga ggtatttttt tctttttttt gttcgtgctg taaggttaag gcaagacaag
     7741 ttagttggga aaaaggaaag aaatgtttat acttaaagaa taacagaaag gaaggtcgca
     7801 tgaataattt tatacaaaca ttaagtgaaa gaaaaggcga gttgctggaa gctgcatttc
     7861 aacatctgtc catttctctc atttctttgc tgattgcagc actgattgct attcctttag
     7921 cgatttgggc agccaatcat aaaaaaatgg cagaagtctt attgcagatc acgggtgtgc
     7981 tccaaacgat tccttcactt gccttattag gtttacttat cccatttgta gggatcggaa
     8041 ctgttccagc attgattgca cttgttattt acgctttgct tccgattttc caaaacacgt
     8101 atattggtct agctgaaatt gacccgtcta ttgaagaagc agcggtagca tttggtatgt
     8161 ccagaatgag acgcttgctg aaagtagagc ttcccatcgc attacctgtc attatctcag
     8221 gtatccgaac tgccttagtt ttaatcatcg gtacggctac tttggcagca ttgatcggag
     8281 caggtggatt agggacattt attttgttag gtattgaccg aaatacacct gttttgacat
     8341 tgattggtgc gatcagttct gccttgcttg caattatatt cagcggactg attcgctggt
     8401 tgcagcataa gaaacctcga tattccatca ttactttagc agcagtggtg tgtttatttg
     8461 gcggcgtttc tttatatcag tctgccttgt ttaaaaatga aaccatcacg attgctggaa
     8521 aattaggagc ggaacctgaa atcctgatcc aaatgtataa agaattgatt gaagacaaca
     8581 caaaaacaga agttgaatta aaaccgaatt ttggcaagac gagttttttg ttcaatgcac
     8641 tggatcaagg tcaaatcgat atctatcctg agttcacagg tactgtccta gaaagcttgg
     8701 tgaaggtacc tgaagcaatg aaaagtgctg atttgacaaa agaaaaaaca tatgacgaag
     8761 cagaagaatt attgaataag caattcgata tgacattatt aaaaccaatg gcttaccaaa
     8821 atacgtatgc cttggcagtc aagagatctt ttgcgaacga acatcaactt aaaaagattt
     8881 ccgatttggc agctatctct gatcagatca aagcgggatt cacactggaa tttattgatc
     8941 gttcagatgg atataaagga atccaagaag catatggctt gaatttttca agtgtacaaa
     9001 gcatggagcc aagtttgcgt taccaagcaa tcaataatgg agatgtcaat attgtggatg
     9061 cctattccac agatagccag ctcaaggagt acgatctagt gactctagaa gatgatcgag
     9121 ggttattccc agcttatcaa ggcgcaccgc tgatgaaaaa agattttgct aaagaacatc
     9181 ctgaaatcgt taaagcactg aataaattaa gcggaaaaat aacagaggat caaatgattg
     9241 atatgaatta ccaagtcaat gtcgaaaaga aaaagccgac agaagtagca cgaatcttcc
     9301 tgaaaaatga aggattagta aaggaggaag atcagtgact aaattaatcg agttcaaaca
     9361 tgtgcaaaaa aagtatgatg gaaagtatgt catcgatgac ctaaatctgg caatcaaaaa
     9421 aggagaaatc tttgttttgg ttggtccttc cggtagtgga aaaacaacta ctttgaaaat
     9481 gatcaatgga ttatctaaac catcagcagg agacatctac ttcaaaggaa aatcgttaaa
     9541 tgaatataat ctgcagaaaa tgcggtggaa tatgggatat gtgctgcagc aaatcgcttt
     9601 gttcccgacc atgacagtca agcaaaatat tgaagtcatc cctgaaatgt taggttggga
     9661 aaagcagaaa agagcagacc gtgtagatga acttcttcaa aaagttggct tatctcctga
     9721 tatttatcga gatcgtatgc ctagagagtt gtctggagga gaacagcaac ggatcgggat
     9781 catccgagct attgctgcaa gcccagatgt gattttgatg gacgagccat ttagcgcatt
     9841 agatccgatt tcaagaaact cattacaaga attggttttg tccttacacg aagaattggg
     9901 cacgaccatc gttttcgtta cgcacaatat ggaagaagca atcaagctag gtgatcgtat
     9961 tgcatttatg aaggatggag aaattatcca atgtgacaca ccagagcagt tattgatgaa
    10021 tcctaaaaac gactacgttc ggcatttctt tgatgaaccg aaacagacga aagagtggcg
    10081 agtagaagat ttagtcgtca atggatattt cttaaatgaa ataccagaaa atgctcgtca
    10141 acaagtttgc tttgatacgc ctatgaaaga agtatattcg cttctttcgg tgtatccaag
    10201 cattgtgata gtagaaaagc aaagaagtat tgggtcgctg acaagtaaag aaatctttgc
    10261 ttttttaagt cgagaggagg aaggaaatga aaacatatga tgcaatcatc atcggttcag
    10321 gtgtgagcgg cttaagtgct gcttatggat tgaaagaagc aggtaaaaca gtactagtgg
    10381 tcgaagaaga tctatggggc gggacttgtc ctaaccgtgg atgtgatcct aaaaaagtct
    10441 tgttaagtgc agtagaggca cgtaatcggg taaaacaatt gagtggaaaa ggttttaacg
    10501 agatcccaac tgccaactgg gaagaacttc aaaaattcaa acgaacattt acggatccag
    10561 tcccagaaag ccgaaaaaaa caattagcag aagctgaaat cgatcatctt tcaggaaccg
    10621 ctcgtttttt ggatgattca tctattgaag tcaacgaaga agtcttccat gcggattact
    10681 tagttttggc aaccgggcaa agacctacga tcttaccagt ggagggaaag gaatacttga
    10741 aaactagtgc agacttttta tcattgcctg tactgcctaa agaaatcatt tttatcggtg
    10801 gtggttatat tgcttttgag ctagctacga ttgccaatgc tgcagggagc aaagtaacca
    10861 ttgtccatca taatcaacgg ccattaaaag aatttgaggc gtctttggta gaggaagccg
    10921 tccatcaaat ggaagcatct ggcattcagt ttgcttttgg tgttgaaacc caaaagatca
    10981 tttcagaagg tactcgctat cgtttagtcg gaaaagagac ggaattagta gcagatatga
    11041 ttttttgtgc gactgggaga cagccgaata cagaatcttt agcacttgag caagcgaata
    11101 tcgtctttga taaacacgga attgcagtca atgattatct gcaaacgagc aatccaaaaa
    11161 tttttgcgtg tggagatatt gtttcaagga aaaccccaaa attgacacca gtcgccactt
    11221 ttgaaggaaa ttatgtagct aagcggataa cggatgcaac aagcgaacct atcaaatatc
    11281 cgattatacc tacgatcgtc tacgccagtc ctaaacttgc tgaagtagga gttacaaaaa
    11341 gtcacgcctc ttcgtcagat caagtggtag agatggatct taccagttgg ttcacctatc
    11401 atcgtgtcaa tgaaccagtt gctaaggctg aattgacctt tgaccagcaa aattatttga
    11461 ttggtgctgc agtgattagc gagcaagcag acgaattgat cgatgatttg acactcgtca
    11521 tcaatcaaaa attgactaaa aaagagttgg atagctatat catggggtat ccgacattgg
    11581 caagtgatct ctcctattta ttgaaataat cagcatgata actaaagcgc ttgttgcttt
    11641 ttccttcttg tgctacactt taaaaaatga atacctgttt ctggggatgt cgtagacgac
    11701 atgagagtaa gttgtgaact tagacccatt gaacctgtca gttaatactg gtgaagggag
    11761 aaacatagca gacgcttgaa gcgggttact atgtcgtgcc catttcaagc gttttttgtt
    11821 attcatatta gaagaaagga ggtaacaaaa tgaagaaaaa tctttatcca gcagtcagta
    11881 tggcattcat tttaattatt tggcagattg ttgtcatagt ttggaaaata cctgccttta
    11941 ttttacccgg acctgctgct gtattttctg cattagcggc agatgcacaa gtattacttt
    12001 cccattctgt cacgacatta aatgaagcag tgcttggttt ggtaatagct agcgttcttt
    12061 cttttattac tgccttggca atggattatt ggaagttttt agaaatgtct ttttatccgt
    12121 tactagtgat ttcacaaatg ttgccaatca tggtgttagg gccattactt accctatggt
    12181 ttggtttcgg tatgcttcca aaagtgatcc ttgttgtctt gataagctat tttccgatcg
    12241 tagtttcttt ttcggataca ttgaggaaag tatcaaaaga gcaaatcatc tttttgaaaa
    12301 cgatgggggc agatacaggg aagatttatc gaatatataa aataccagcg ggtttatccg
    12361 gcttcttttc cggtttaaaa gtggctgcta cttattgtgt cagcggagca gtcgttggag
    12421 aatggctaag cgctcaagca ggcttagggt attacatgat acgcgtaaaa aacagctacc
    12481 agatcgataa agtttttgct gcgatcattt gtgtcattct attgagttta ttgctgaatg
    12541 gcgcttgttc attattgaaa aaagggtatt atcgtatgct ttatattttt taagagaagg
    12601 ggatcaaatg aaaaaattat ggcttttatt accgctactg ttgcttttat ccgcttgtgg
    12661 cactgcaaaa gaaacaagta gcaaacaaga aataaaggat ttgaaaaaag tgacacttgt
    12721 tttggattat gtaccgaata ctaatcatac tggcatctac ctagcaaaag aaaaaggcta
    12781 ttataaagag gctggtttaa atgtccaaat catcgaacca ggagataatt cgacaagtat
    12841 tggtctagta ggtgcggaca aagcacaatt tggtgtaagt tatcaagaag atgtcactta
    12901 tgctcacgca gatggacaga atataccagt caaagcaatt gctacagtga tcaaacataa
    12961 tacttctgga ttcgccaccc tatcagacag taacatccat tcaccaaaag attttgaagg
    13021 aaaaacatat gcaggttggc aaagtccaag tgaagaagct gtcttaaaag ctgtgatgga
    13081 aaaagacggc ggggactttt caaaactgac aatggtagga agcaatggag aagggccaga
    13141 aagcttagga aaatcctcag atatccaatg gtactttgaa ggttgggata tgatcaaagc
    13201 aaaagaagcg ggtattgaac taaactatat cccattgaaa gaattagatg aacggttaga
    13261 ttactatact ccggtaatta ttacgaatga tcaactgatc aaaagtgatc cagaattggt
    13321 acagtctttt atggatgcca cgaaaaaagg ctatcaggaa gctattaagg atccaaatga
    13381 cagtgctaaa ctgttgcaaa aatatgcaaa agaaaatgat cggacgtttt tagaagaatc
    13441 acaagcattc ttgtcaaaaa attatacgga tgatcctgag aattggggat tgatggaaga
    13501 aaaagtttgg cgcaattata cagcttttat gcaggaaaac ggattgatca agcaagatgt
    13561 accttcgcaa gaactattca ctaatcagtt tataaaatag gagtgataga tatgtcaatc
    13621 caaatcagcc acttgaatgt agtcattgaa aacctgaaaa tattagaaga catccatttc
    13681 actatcccta aagatacctt tacatcgatt gtcgcgccaa gcggagccgg taagtcaaca
    13741 ttgctgaaaa ctttaacagg agtccagcct atgacttctg gaacgatcaa agtagacgat
    13801 caaaaagtaa ctggtctcca tacagcattt agttatatgc cgcaagaaga tatgttactt
    13861 ccttggctga gcgtctatca aaacgttacg ttatatcaaa aaatcaatca tctaacaatc
    13921 aatgaagaac aagtaaggga ttatctggat atctttgggt taaacggcta tgaacatttt
    13981 ttgccggaac aattatctgg cgggatgaag cagcgaacgg ccttgttacg aacaatcatg
    14041 aatccttctt cttacttgct tcttgatgaa ccatttggag cgttagatgc tatgaccaga
    14101 gggcagatgc aagactggat gttgaagctg cctaaaaaag caaagcggac tactttactt
    14161 gtgacgcatg atatcgaaga agcaatttat ttatcagaca ggattcttgt gctttccgcc
    14221 cgtccggcac atgtgattgc tgagattcaa gtgcctgaaa aacgacggtc acgtgaatgg
    14281 ctactgcagc aatcagagtt gaagcaaacg atttatcagt tattggcagg tgaattagat
    14341 gttaagtgat gctcattgtc atttagatgg gagtcagagt ttagcactcc ttcagcagga
    14401 acacacgatt ttgacgatca tcaattgtga ttcgccagaa gaatggaagg aaaacagaca
    14461 gcttgcagca agtaagactc aagccttaag ttacggtatc catccttgga aagcagatag
    14521 ctatacgttt gaacaagttg agcctttttt gaaaaaagca aggatcatcg gtgaaatagg
    14581 gttagataat atttggacga atgtaccgat gactacacaa aaaaaagtat ttgagcgaca
    14641 gcttgctttt gcagccataa atgagaaacc tgttgtactg cacacaaaag gatgcgaaaa
    14701 agagatctta aattatatcc aagcttaccc taatcactat ttgatccatt ggtattcttc
    14761 tttggactat caacaagact atattgattt aggctgttat ttcagcattg gtcttgattt
    14821 gaaaaagaat ccagcagtct ggcaactagc taaagcagtc ccaatcgacc acttacttat
    14881 tgaaacggat ggactacatg cagcagagtg ggctttaggg gggatttttt cagaaaaaga
    14941 ttatgtctca ctgcttgaag aacagttaaa gacaatcgct gagatcaaag agctatcagt
    15001 tgaagaagtt aaaaaaaata cttatcaaaa cttggaacgt ttcattagat taggtaaata
    15061 aaaaagagat gtgacacaac tagtgtcgca cctctttttg gctttctttg tataaaagta
    15121 aactgtttga ttaataaatg aatcttagta ccaaccgttt gcttcccaga atgctttcgc
    15181 cgcttcccaa gaaccataac gtgaagtaac atattgttct gctactcttt cttggtttgc
    15241 agcagagtag tcaccattta agtaagaaga atctaattgg taacgtccga tgtaacgtcc
    15301 gttcgttgct gtgtaagaac cgcttgattc tttttgtgcg atccattctt ttgcagagct
    15361 tgtgcttgct ggagtagcag cagtttctgt tacagcagga gcaggttgtg tttcagcaac
    15421 aggcgctgct tgtttttccg tttgaaccgt ttcttgtaca acaggttgtt cagcttggac
    15481 tggtgcttct tgaacggctg cttgaggttc agcagctgct tgtgcagagc cttctgttgg
    15541 gattgttaat tgttgtcctg agtaaatcag gttaatatca gaaattgaat ttgattctgc
    15601 aatggcattg atcaaggagt tatcaccaac gtatttttga gaaatcgttg atagagtatc
    15661 acctgattga acggtataag cttcgtccgc atgagcagtc gttcccatga agaatgcagc
    15721 gccggcagcc aaagttgttc caaaaagtaa agttttaagt gatgtcatga aaaatctcct
    15781 ttattcgtta aaaagtttta tttgttgtgt tcaacgagga atactttaac acgtgaaaat
    15841 atttcatagg taaaagaagc atgacaattt atgacaaatc cgcgtttttt gtaataaata
    15901 cagtaatcta tgaaatgaaa agggttacgt ttaataaaac ttgctttttt gtttttgttc
    15961 accataaata tttatttaag aaagtattaa cctgcatttt tctctataaa aaagattttt
    16021 taaatagata aaaaaggagg attaaatgag tatttgatag tatttatatt aaaattacat
    16081 atgtaattta aaaacgcttg acattgtgtt tgagatcact tacttttagc atgtaaaagt
    16141 attggattaa ggagctatgc aaatgaaaaa gaaatttatt actggtggga ttgtcgttgc
    16201 atttctatgt ctaattggct acacaggcac gcggtacgca aatgaaatta ttttgtgggg
    16261 tggagagaca gatattgata caatcaatga gaatctgaca cagcttgatc atacattgac
    16321 agataaagag caagcgatta cagatcttac cgctcgacta gcacaaaaag aacagacatt
    16381 gcaagattca aaggcagatg tccaagaata ccaaacaaaa gtaaatgaat tagaaaacca
    16441 aaaaaatcaa tcggcagcag aaaaacaaaa cttagaaagt caattagtca gcaaggatgc
    16501 acaactacaa agcaaacaaa atgaaatcaa tgtcaaacta gatgagatca accaaaaaaa
    16561 tgatgaaatc aatcatctga atgcagattg gacagcaaga ctacaagaag cacaagcaaa
    16621 actttcagaa ttacaaaata ctgtaaatgg tttgaatcaa caaatcgcaa cactgacaca
    16681 agaaaaaaca aatgtagaaa tcagttaaca gatacacaaa agaaattaga cgaagcaact
    16741 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
    16801 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
    16861 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactgct gcctcttttt
    16921 tttagtacat gtccttcatc ttcgcaggaa gtgccaatat gattttaaga aaggtaatag
    16981 acaaaaagtc aaaaagataa aacagagttt cttctttaca aagggaatgt atgttcgtat
    17041 aatggtattg aggtgaaggt tatggagaaa aaatatggaa cagtagataa gatccgtact
    17101 ttgcaagtta gtgccagacc gttgatccgt ttcagtttaa atggggtcaa ttgtttgatt
    17161 gcttcccata gtttgaactt cctagctgaa gtagacgaag ggatgaagtt agtcgttaca
    17221 ggttattata ataatagaaa gcaatttgtt gtgagatcct atcatgtgtt agggaaaccc
    17281 aaaattgtgg tagaatatga gaaaagtcta tacccaagaa aaaaggtccg acaagatgaa
    17341 agaataaact agaaaacaag cggctgagac aaaaatgtcc tagccgcttg ttttggaaag
    17401 atggatgcag acgatgggat ttgaacccac acgagcatac gctcacaaga acctcaatct
    17461 atatataact acatgtattt aagtatttgt gatgaatcac taaactttcc aaactcattt
    17521 gagggatatt gcttaaagat tgaacagatc aattcgaagc cctattagta ttcgctcaat
    17581 ggggggatca gaggccataa aaagagacta gtcattacta gtctcaggta gtggaattgt
    17641 aggattttaa acgttcctgg agagtaccgg tatgtaactc gaagaggtga ttatcatagt
    17701 cgtaaaagta aattgaagaa gcctcgcctt tcacacgaga acgtcctggt tcgacagtta
    17761 aacctaacat ttggattttt gagacaaacg aatctatatc ttgttcgtca attttaaaag
    17821 caatatgatt gtatgtcttt ggcagtttat tcgacgaatt ctgcattact gcaatccata
    17881 ggtccttaac taagaaaaat ttttctggat ataatgaaaa tttttttgtt gactatcgta
    17941 gatttctttt gcatcaaata aggtatttaa caattaagta tttaaaagat aacttttaag
    18001 ttatctttaa gtaatgctta aagctatgtt atactctatt aggaaatata agaaggagta
    18061 taaaaatgaa caaacataat agaaaaataa cgaataacaa agaactgatc ttgttactaa
    18121 tagggatttg gggtatcttt ttactcttta atatgtatat gccgactatg agagcggatg
    18181 acgtagttta tgcaagtaga ttagatgaac ttggctattt gggtgcttcg atagaacatt
    18241 ataagacatg gagttcaaga attattatag aactattctt aatgttcttt tctaaacact
    18301 ttatgctatg gaaattatta aattctacga ttatgttagg aattgtagta ttactttgca
    18361 agtatg
//
LOCUS       DAFEML010000046        18322 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFEML010000046
VERSION     DAFEML010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.047"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(713..1396)
                     /locus_tag="LP468_001896"
     CDS             complement(713..1396)
                     /locus_tag="LP468_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2081411.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(1414..2031)
                     /locus_tag="LP468_001897"
     CDS             complement(1414..2031)
                     /locus_tag="LP468_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2081412.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(2041..2865)
                     /locus_tag="LP468_001898"
     CDS             complement(2041..2865)
                     /locus_tag="LP468_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL2081413.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(2858..3418)
                     /locus_tag="LP468_001899"
     CDS             complement(2858..3418)
                     /locus_tag="LP468_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081414.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            3592..4548
                     /locus_tag="LP468_001900"
     CDS             3592..4548
                     /locus_tag="LP468_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2081415.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(4853..5809)
                     /locus_tag="LP468_001901"
     CDS             complement(4853..5809)
                     /locus_tag="LP468_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL2081416.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            5913..6515
                     /locus_tag="LP468_001902"
     CDS             5913..6515
                     /locus_tag="LP468_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2081417.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(6603..8102)
                     /locus_tag="LP468_001903"
     CDS             complement(6603..8102)
                     /locus_tag="LP468_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL2081418.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(8118..8642)
                     /locus_tag="LP468_001904"
     CDS             complement(8118..8642)
                     /locus_tag="LP468_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL2081419.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            8940..9689
                     /locus_tag="LP468_001905"
     CDS             8940..9689
                     /locus_tag="LP468_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2081420.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9680..10465
                     /locus_tag="LP468_001906"
     CDS             9680..10465
                     /locus_tag="LP468_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL2081421.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            10434..11150
                     /locus_tag="LP468_001907"
     CDS             10434..11150
                     /locus_tag="LP468_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2081422.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(11252..12286)
                     /locus_tag="LP468_001908"
     CDS             complement(11252..12286)
                     /locus_tag="LP468_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL2081423.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(12290..13348)
                     /locus_tag="LP468_001909"
     CDS             complement(12290..13348)
                     /locus_tag="LP468_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL2081424.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(13569..14717)
                     /gene="nagA"
                     /locus_tag="LP468_001910"
     CDS             complement(13569..14717)
                     /gene="nagA"
                     /locus_tag="LP468_001910"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL2081425.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(14793..15629)
                     /locus_tag="LP468_001911"
     CDS             complement(14793..15629)
                     /locus_tag="LP468_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081426.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(15813..17030)
                     /locus_tag="LP468_001912"
     CDS             complement(15813..17030)
                     /locus_tag="LP468_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2081427.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(17179..17358)
                     /locus_tag="LP468_001913"
     CDS             complement(17179..17358)
                     /locus_tag="LP468_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081428.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            17413..17496
                     /locus_tag="LP468_001914"
     tRNA            17413..17496
                     /locus_tag="LP468_001914"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17447..17449,aa:Leu,seq:gag)
     gene            complement(17736..18314)
                     /locus_tag="LP468_001915"
     CDS             complement(17736..18314)
                     /locus_tag="LP468_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081429.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         5429 a         3786 c         3186 g         5921 t
ORIGIN      
        1 agctaagatg attctcattc ttttcttcat tctctgcacc tctacttcca ttgttatttt
       61 tcaatatact gtatttttat acagaacata tttattaaac gatctttttc aaggggaata
      121 aaaaccaaga cttgccttat cgttctgcct aggatgaaca actcaatact ttcaagaaaa
      181 attagatagt gctgattctt ctttcatcgc taaaaacact tcttgcttca atgatgggag
      241 gataattacg caaagaaaaa aggatatcag acaactgccc aatatccttg acatagctaa
      301 ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca gaaaaataac tagtaattct
      361 gtatgaaatt aggtacaata tacacgtcga tgcacaagca ttgactatgg caacttgatt
      421 ggtcagttcc cgctgacttt tcaagccccg acaatttagc tgctactaaa ttgtcgggtg
      481 ccttttttag tttttattcg tttttcattc tatagaaagc gcttcaataa atcaagacat
      541 ttttttgtta gaatgctaat aataacaaaa ggttttaact cttcttatgt acattacagg
      601 taaaaaaaca aaaaaatttc tctttttttt gaattctgaa caaatagtac tggagtacaa
      661 aagacgagga agagccacta tctgctcttc ctcgtctttt gattctcacc tgttattcat
      721 gattcttttt ctcagtttcc cgatattttt ccattttacg actaaaaagc tctccgctac
      781 ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat ggtctcagca atactttctt
      841 ccgttggacc acctgtcgca atgataggaa gttcaggata ttttttacga aaatggcgta
      901 ctgcttctgc agtttcttta cctgcactga tattgataat cgaaatacca gctgctaact
      961 tttcatctat ttctgtatat ttcgacgtta ccgtactgat aactggaata tcaactactc
     1021 gacaaacttc ttttactgtc tctaaaggcg taggaccgtt caaaacgacc cctaacgaac
     1081 cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc accttgtgtc aaaccaccac
     1141 ctacaccgga gaaaactgga atgtcagctg cctcaataat gcttttagta atcgctggat
     1201 gaggtgtaaa aggatacaca gcaattactg cattcgcatt tgtattacgt atgatcgcaa
     1261 tatccgtagt aaagatgatc gaacggatca attttccaaa tatcttgatc ccgcttgctt
     1321 ctaaaatgat ttccggtact cttacgatat cttttctcaa ttccgtcatg atttctggcg
     1381 taaattgttc tgccatcagc cacttctcct ttgctatctc cggtcatact gattcaattg
     1441 atacgtctcg atgacctgga tgattttttg cgcataaccg gggtctgtcg cataacctgc
     1501 atcttgcaat gcttgtgcgg cttcctgata gttggtggcc gtaatcactt tttcatacag
     1561 cgcaggattc caatctactc cttggacgaa cagttgtgta tggtcatcca tggactgttc
     1621 ccatgaatca tacactttga agtctccttg gatagttatc cattcttcgt taacaaattc
     1681 ctttgtttcc aggcttactt tcttctgatc cccataagcc ttgatcccga aaagattatt
     1741 gtatttgcta gccaaggtac tttttcccca atttgattct aatatagctt gtcctaaaat
     1801 gatactagga agcactccat aaccatcttg tagttcttgg gcatgcggaa caagccgttc
     1861 aataaattgc tgatgggatt gcgcttcatt ttcttgctga ttatcagtaa aaggagaaga
     1921 cagattcttc aaggaaaaaa caaaggctaa gagtatcact gctacaccgg caaccactgc
     1981 tggccaacgg atattcttgc gcttttgctt tttccacttt tttttcgcca tgatcaattc
     2041 ctacttttca tttaattcat tcagatattc ttctagcgtc aattggtgtt tggtgatata
     2101 ctcagcgttt tctttaccga cataacgtaa gtgccaaggt tcatatgtga tcttagttat
     2161 atcttcgtgt ccttttggat aacgaacgat aaatccatac tgcgcagcat tatctgcgat
     2221 ccatttagct ccaggctgat ctccgtaact tgcatccaat acagtagaag gataactgtt
     2281 gtaccagttt tgatcgacga catcgactgc cagacctgtg tggtgttcgc tgtatcctgg
     2341 ctccgtaatc gtttctttag taatctttgt cgcctcctct tctgatacac cttgacgact
     2401 catcacatct tggacatttt gttcgaaaac ttgttgttgg gatgatacag accggtaagc
     2461 tgagaccatc actaatggaa atccagctgc ttcagcagcc ttggcaaatg cttcatattc
     2521 tggagcaatg cgtttgtcga tcaagtatcc gttacttaat gatgccaatt gagtagactc
     2581 atcaatttct ttttctaatt tgtgatctgg accaaccaaa actagcttcc aatcgtctgt
     2641 tttaacatct ggcaattgtt tggacgtacg atcttttgtt tctttgtcct ttaccttgct
     2701 gctggttgtt tgactgttct tttctttact agcagttgtt ttggtgcttg ttcgttcgac
     2761 tgcttgattg ccggcttgaa catgcgaatc atcatcgcta aaaataacat agcccattgc
     2821 tgcgatcata atcacaactg ctccaaatcc taaaaattta ttcacttgaa aaatcctttc
     2881 gttgttcttc acgttcccca ttcgcctcat gaacgtaagt ttcttccaga ttttcattca
     2941 cccaatcgag aagttcgatt ttttctcctt cgatctgttt ttgaacatct gctggcagac
     3001 gaaaattcaa aatatcatca tagccccatt catcatattg aatacttact ttcaagtcaa
     3061 ggtatctacc agcctgctga ttatttttca aagggatcag ctcgactttt gctgctttgc
     3121 tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt gtactctgca acggcaacgt
     3181 ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt ttgcgttagc atccattcat
     3241 aatcagtgaa aagatttttt actttctgca tcgcttcaga tggcagattt ttctcgccat
     3301 ctttccattt ttgccattgt tctggactga tcagcaagta ttcatctaaa aaattttttt
     3361 cagtttcaaa ctgttctaat aatacactca taataagatc aatatatact tgatgcacgt
     3421 ttatcccctc cttttaacta ttctacttaa gttttgatca aaaagcacct cttaaatcgc
     3481 tgctttcatt ttttttaatg tttcaagtcc tctcctcttt attcttcgtg atttttgtta
     3541 taataataga cagacaagaa actcaatcca actatgaagg agcgttttca gatgaaaaaa
     3601 tatcaatggg gaatcgttgg tcttggtacc atcgcacatg agtttgccga aagcttcaat
     3661 caagagacga gcgaactaac agcagttgct tccagaactt cagaaaaagc ggaaaacttc
     3721 gctcaccgtt acaatattcc aaaagcttac ggaagctatc aagaaatgtt agacgatgct
     3781 gaaatcgaca tcgtgtacat tgctgtacca aatagacagc atatcgacca tatcttggca
     3841 gcattggaag caggcaaaca cgttctatgt gaaaaagcca tcacgatgaa taaaaaagaa
     3901 ctggctgacg ctatgcgctt agcagaagaa aagaatttga tcttagcaga agcgatgaca
     3961 atcttcaaca tgccacttta tcagcagtta cgctcaataa tggatacagg aaaactgggg
     4021 gctttaaaaa tgatccaagc acctttcggc agttacaaag aaccagaccc taaaaaccgg
     4081 ttcttcaatc cagaattagc tggaggagct ctgttggata tcggtacgta tgctgtatct
     4141 ttcgctcgtt tctttttgag ctctcaacct gaagtagttg cctctacaat ggttcctttt
     4201 gaaacaggcg tggacgaaca atccgtcact atcttgcgta acaaagaaaa tgaacttgct
     4261 gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg gtatcgttgc ctttgagaac
     4321 ggttatgtga cgattgctga ttacccgcgt gctgatcgtg cggagatctt atttacagat
     4381 ggtacaaagg aattcatcga aagcgggaat acatctgaag caatgaatta cgaaataaag
     4441 aatatggtac acatgattga aggtgacttg cccaatcgct ctctcttctt gacaaaagat
     4501 gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa atatgtaatt ttaaaaggtt
     4561 gtgaaaaagc tgttctgcat caagtaataa gaacagccaa acaaaaatag ctcctcctat
     4621 ttttcgtttg gctggactta ttaccgcaga ggaaagcttt tgaacaccgt ttaagaaaga
     4681 ggttgtgagc ctaccgttca gctccgagtc acaaggagca atttcaaaaa acagcttctc
     4741 atgtttgttg aatattgtga cttgtgaccg aggagttgac aggagaacac cgtttaaaga
     4801 agaggttgtg aaatcagctt tttgacctga atattagctg aattcacaac ctctattttt
     4861 ggattttttg ttgggagaat tctgccttga tttcaataaa acttttaaaa gactgcaaaa
     4921 actggaacaa ttctgctcga tcctcgaatt cagggcgact agtcggcaga ggcatttgcc
     4981 gatacaatac ataaacttct tcaatacgtg ttaaaatttg tctgccatca tttgactctg
     5041 aaaatgtttc tgcagtataa atcaataaac catagatatg ttttccataa taagctggtt
     5101 gctggattct ctctagattt tccagcatgt ctttaatcac attggcctgt gctcttctca
     5161 tagagaagta agtttcgtag tatagcggct gtctgagcca gtagttttct tgatgttctc
     5221 tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg ttcgcatttg atctgcacat
     5281 cttctttatt ttctgataaa agaaattctg ccatttgtct caaaatattt cgaaattctt
     5341 tttcgatctg tatttggttt tccttcagct gcttcgtacg atctggcatg taaacatttg
     5401 caagcaaagc aaatactaat ccaatcgcca ttaatcccgc ttcattgccg atcagctgcc
     5461 aagacatgtt ttcctccact aaataatgag tgaccaaaac cgaatttact actatccctt
     5521 cggttaattt gaagcgagag gcaagcggga tgaacaggaa taaaaaaaga ctgaagccaa
     5581 aaatagtata cccaacagca aaaaaactga acagtgctgt tgccgtagct aatataaagg
     5641 ctgcgattcg attcatgccc gtacgcaatg tagagcgctt ggtatttcct acacttaata
     5701 atgcaatgat ccctgcagct ggccaataca acagcgataa gctacccgct gtgaccatcg
     5761 aaaagaagac actgatcact gttttgactg ttcgcattcc tatacgcatt tacttccccc
     5821 ttttttattt taattatact tgaataatga aaaactagct atcagacaaa agtttaggta
     5881 tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt tggccgtttt cgactaggta
     5941 tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat cttgtttttt catttgactc
     6001 aacgaggaat cccgatgatt gctgcattat ctgctgtttt ttctttgcgt caggacttga
     6061 ctacaaccgt ttcttttgga aagtctagga tcatcggcaa tacattaggt ggtacattag
     6121 ctatcattta tttttttgtc aaaagctatt ttcacaatga ttttttggta gaattgatct
     6181 tgcttcctat tctagttatt attgtgatcg tcgtgtcaga tggtattaac aataattccg
     6241 gtatcatttc cgcaatagct acgttgttgc tgattgcgtt gagcatccct caaggcgaat
     6301 ccgctttgta tgctatccaa cgtgtactag atacttttat agggacattc attgcaatcg
     6361 gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa ggaagaacta tcagaagatt
     6421 tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa tttacaagag atagaagcta
     6481 agatccaaaa acaaaagaaa aatagcgagg actaattttc ttttgcaata aaataaaaaa
     6541 atggagagaa gaactttaaa aagtcttcct ccatttttga ttgaacggtg aagtgtacta
     6601 ctttattctt ccttcatcga gttttgttct gcctcttttg gcgcttcata catatttact
     6661 tggctagtag tcccacgtgt cgacaaattc tctacgattt ccttcaagtc aagtcctgtt
     6721 gtcgctttta gtgtttcttg agtagaagaa agcaaatttg tggcataatt tgtcactcgg
     6781 ttcgctccac tggtttctcc tgaactgctt cctgtatcga caacagagat tttttcgata
     6841 tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta gcatatcgat aaccatactc
     6901 aagacagctg cttcgccata ttccttgaag gcattggcga tcttttgttt tgcttcggct
     6961 tctgcttttc cttttgctag tgctgcttcg gcttctgctt gtccagctaa acgtgtctta
     7021 ttggcttccg cttctgccag tgcttccaca cggaatcgtt ctgcttcggc ttcagtcact
     7081 tctttgactt tttgagcttg tgcttcttgt tctttagcgt accgatcggc atctgctttt
     7141 ttcttcactt ccgaatcata ttgcttttca cgacgtgtga tttctttttc ttccagttcg
     7201 atttgttttt gacgttctac gattttaatc tgcatttcct gttcgattac ttgttgttgt
     7261 gctcgggcac tttctaaatt gtaggcttgg tctgcttttg ctttagcaac atcttgttct
     7321 tgtttgtagg ttgctaattt cagttctttt tcttttaatg attctgcgat ctctgtttgt
     7381 cgctgtaatt cagctgcttg tgattctttt tctgcttgag cttttttgat acgcgtttct
     7441 tttagagctt ccgcttctgc tatatctgca tctcttttga cttgggcgat tcttggtttc
     7501 cctaaagagt caagataacc gtttttgtct ctgacctctt tgatagtgaa agaaacgatg
     7561 atcaacccca tttttgcaag gtctacagaa gcgacttctt gtacgctttg actgaactta
     7621 tcgcgatttt gatagatttc ttctacagtc atagaaccaa gaatcgagcg caagtgtcct
     7681 tctaatactt ctcttgcttc attttccagt tcttctcttg tcttgcctaa aaactgttct
     7741 gctgctgtag caatctcttc tacagatgaa ccgattttga tgatcgaagt accatcacac
     7801 atcaccggta cgccttgttc cgtatacact tcaggggtgg agacgtccaa tttactcgat
     7861 aatagactga tccgattcga acgttgaaaa actggcaaga cgaatgcgcc acctccacgc
     7921 acaattttga ttttgttatt gctttcatca atgtgcacat ttttgcttcc taaataactt
     7981 ccactgatga tcaacgcttc atccggtttt gctgtctggt acttcgctac aaagacgatc
     8041 agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga taaaaacaac tggtatttcc
     8101 atttaacaca cgctccttta agcttttatc atgctttcat aaggcatgac ataacagatt
     8161 ctttccttga tctcaatgat caatactttc gttccccgct cagctgtctg ttcttggggg
     8221 ctgtaaaaac aagctggacg actaatggaa ccggtaacac ttttcaactg aatttctccc
     8281 atacctcgta cagggatcgg tgtgatcaca acagctactt gtccttccag agttttttca
     8341 gaagacgaca tcgttgattc ggcatgtttc atcggcatca atatatagaa attaagcaaa
     8401 aataccaaca ctatcgatat gcctccacta gcaataaata aaaataaaga tgattgatct
     8461 gttaaacgct cacctagaaa accaaataag cttgtgaaag ttaaccaagg gataataagc
     8521 atcggatcaa gcgggccatc aaaatcgaat acatctccaa aaataatcaa taggactgcc
     8581 aatcctgcac aaatcagcaa tgtataccaa taaatcgtct caagtgcgat tccccctatc
     8641 atatacacgc ctccttccat ttctacgtct atcataccaa tgtttgaaaa ttctgtatag
     8701 cttcttttac cgactcagtg gtgtttttta taggaaggtt gtgtttatcg ttgacaattt
     8761 gttaaatttt tgttttcatg ttaaaatttt cacaataaat tctttcgagg tagcctatgt
     8821 ttcctttttt taagaaaaaa ccattaaagc tccagaacac gatcatcctt gtcgtttgtt
     8881 tctccacatt cgtttctttg attgtttctg ccatattgat caggaatttt attctttcga
     8941 tgaaccgatc tagtgtgtca gataaaatct ctagcattgc taaaatcgtt gccaatgata
     9001 aactcatcca aaaaaagctg cagactggtg acccgacaca tgcgattcaa ggaataacaa
     9061 atgaaatcat gattgcatcg aatttagatt ttatcgttgt catggaccct gaaggcattc
     9121 gatattctca cgcagaccca agttacatcg gtcttccttt ctcaagtcat gaagatgtga
     9181 aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga aggaatgtta gggttcggct
     9241 tccgctattt cgtccctatt tattatgatc aagagattat tggtgcagtt tgtgttggct
     9301 taacaaacaa cacgattgac aatcaagtca aagatggaca aaaaatgatt gttttttcat
     9361 tgattattgg acttagcgta ggcatcatag gcgccgtttt tcttgcccaa aaaatgaaaa
     9421 aagtactgct tggacttgaa ccacaagaaa tagcagaaca gttaagtgaa aaaacgatta
     9481 tcgaaaatga agtagatgaa ggaatcttag ccatctcttc tgataaaact atcctcttga
     9541 tcaatacacc tgcaaaaaac attttctacc aaacagagca gctattggat ttcgaagtag
     9601 gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa gagacgattg agcatcaaac
     9661 gaccgttcgg actcaatcca tgtatttaaa tgggatagaa actatttcta gcgttacacc
     9721 tctttttagc aatgaccgtt ttttaggagc agtcgcaact ttacgaaatc gatcagaagt
     9781 aatgaaatta atggaggagc ttggggggac gaaacaatat ataaactcca tgagagctca
     9841 aacccatgaa ttcatgaata aacttcatgt catttctggt ttgattgatt tgaagaagta
     9901 tgaagaagtc acccatttta tccagcagct aaatcaaaat tataaaaaag agattggcca
     9961 agtctcaagt ctgatcaaag tacctgcaat tgccggtttt ttattaggca aaataaacga
    10021 agccaaagaa caatctgttg aaatgctgtt agaaagcgat tcttttatcc ctaaaatgga
    10081 gatggatgac tccatccatt cacttttgca agtgttaggg aacttacttg ataatgcaaa
    10141 agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc cggattcatt taaactatga
    10201 cacagaagct gaagtattca tcgtgaccgt ctgcgatgac ggtgtcggga tatcagaaga
    10261 aatctcagaa aaaatattta cgctaggttt ttcgacgaag ggaatcaatc gtgggtttgg
    10321 attgaatctc atccattcaa tcgtcaaacg ccacggtgga tttttagaat tttccaaaca
    10381 aacaaatggc ggtacaatcg tctatctaga attaccaaaa aaggaagatc aaaatgatga
    10441 caaatgtcct gataatcgaa gatgatccaa tggttgcaga attgaatcgt acttttgtgg
    10501 aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa tgtagaagaa ggaaaaaaat
    10561 atttcagaca aaaaaacgca gatctgctgc tgcttgatgt atacatgcct ggcgaaagtg
    10621 gtatccattt tttatcttgg cttagacagc aaggaaatga tatcccagtg attttgatca
    10681 ctgctgcaga tgatatcgaa accataaaga atgtgatccg ctacggtgcc ttagattatt
    10741 tgatcaaacc gttcactttg caacgttttc agctggcgat cgaaaagtat cttgctttct
    10801 ctcagacaat ccaaacgact gaaaaagccg atcagaaatt gatcgatcaa gtattcaacc
    10861 acaccactcc cattcacgaa ataccatcat tcatcgattt gcctaaaggt ctgtcaaaac
    10921 tgactttaaa aaaaataagt gcatttattc taaaagaaga tactattttt tcaacaaaag
    10981 aactggctca aaaaagctca ctgtcacgta tatccgtcaa gaaatatttg aattttttag
    11041 tagaacaaga tatattgaac gaaagaatca aatatttgga aatcggccgg ccgctaacct
    11101 gttatgaatt gacaaagaat gggcggaaaa agctcacaga ttactgttga gtcatcgaat
    11161 tatcccatac aaaatagtcc aagtatacag aagtaacaac tgtttacttg gactattttt
    11221 aaacatttta ttgacgaata tccatgtttt cttatcttaa ttgacgggct ttaggaagag
    11281 atacctcatt tttcgttttt ccagtttcta ttatttcacg aaagttctcg aaacttgtcg
    11341 aaatcatatt tgataatgcc tcatctgtat ttgaacctac atgcggggtt acaagaactc
    11401 tagggtacat ttctactaat tgctggatag cagggtctgg aatcgtctcc catggcttga
    11461 aggatcggaa aaaaacctct gtttcatttg caaaaacatc ggttgcaaaa ccagctaaat
    11521 gattgctttt caaagctctt aaaatagctt cattatcttg aagctctcca cgggctgtat
    11581 taatcaagat gctacctttt ttcatttgag ctaaaaatcc ttcattgatc atttgatcgt
    11641 tttcacctgg gatatgaggt acatgaatac tgacaatatc gcttttggct aataactctt
    11701 caagcgagtg gaacgtcaat acttttttag cagcttctgt ctgatgaata tcgtagccga
    11761 tcactttggc tcctagtccc ttaaacaaaa cagcttccgt caaccctatc ctgcctgttc
    11821 ctatgatccc tactgtgcaa tttctgattt cacgactaaa catttgctca tccactcgaa
    11881 aatctttgaa agatgttcgg atcgtcgtat acgcagtatt tctcaaaagc atcatggcaa
    11941 aagtcaaaga taactctgct atcgcatttg gcgaatacga tggtacacgg gctactgtca
    12001 taccaaaatc agctgccgct tgtagatcga tatgattgac tcccacagtc cgtgtaaaaa
    12061 cataacgaat cccatattcc tgcatttttg caagattggt ctcatctgct atacaatttc
    12121 ccctcaacaa tacagcatca tggtcctttg ctgacacgat attgtcatgt gtcaacagtt
    12181 cttcataaag actgagatca taatggtaaa tattcaattt ttcaaaaaaa tctatctcgt
    12241 tcggacgaac accgtaacat gcgattctca tactttcttc ctccatttct tatgaaaata
    12301 aacctatgcc atgaatcatt tgtaatacaa cgatccatac aggtgtcagt accacagcaa
    12361 aaatagttga cagtaaggat gcattggagg ctaaaagtgc ctccctatca aaactgatag
    12421 cataggctgc tgccactgtt gcagctggtg tagccatcat gataacgatt gttgccagtg
    12481 cttcaaaatt gactggtaga atattcgttg ccgtcaaaac tgctagaatc acgatattca
    12541 atgcaggtac aaataccact ttgactagac tgtaatacca tgaagttttt tcagatgcag
    12601 cttttttgaa gcttacttca cctaatgttg cgccgattgc tagccacgcc aatggtgaac
    12661 ttaaaccagc taaataatcc atcggctgaa atagccacgg tgcagtctgg tcaattcgca
    12721 aaaacgctac ttggcttatc tctccttctg cacctgtaac tgacacttgt ggcagatacc
    12781 cttggaacag ccaaatgaaa aggccggcaa aagtagcgat aatgattgga ttgacgaaca
    12841 tcgctttgat atttttagct tccatcttca agccactcat ttttatgtat ccataagaat
    12901 acaaaaagat tcggtagcca atattgaaaa ttgaggaata catcacgccg acaggaccat
    12961 aaatcgcact gacgataggc gttccgaaaa aggtcgtaga accaaagatc gtcaggacac
    13021 gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa aggttttgaa actagaataa
    13081 gaataatata aataactaat ccccaaatca agacattgat tccttgcatc agtaattctg
    13141 tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg caaagccact gttaagacga
    13201 ctttcgatag aatttttcca acagattcag aaaaaatccc cttttttcta caaacaaacc
    13261 ctaataatat aataaaaact gttgaagtga ttgcactgac aatcgacata tctgtcaaag
    13321 tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct aattatgttc atttattcac
    13381 aataaaaaaa gcttttattt tgctaatacg tattaacatt tttaatttta tctttacatt
    13441 gttacttatt gaacaatagg aaattaaaga aacttttgaa acttatgtaa agtgattttt
    13501 actagaacac aaaaaaaacc ttaaaaccaa acttaagaag tttagtttta aggttaactt
    13561 aaattatatt atgcgtggaa acgttccacg ccatctagat aagttgcttc caatgtcata
    13621 tcagggttca atacgataaa gtctgcatcg cgtccttgag cgatttttcc acatgtatca
    13681 tcgattttac agctgattgc tggaatcaga ctagccatca tgactgcttg ttctggtgtt
    13741 gctaatcccc agtctacaac atttttaatt gcttctttca atttcaatat acttccagct
    13801 aagttgccag attctagacg tgctgttcct tcttttacta ctactggaaa ttcgcctaaa
    13861 ttgtaatttc catcaggcat cccaccggcc atcatacagt ctgtaattaa tgcgacatga
    13921 tcatgtcctg ctttttccat taggattccc gcagcatttg gatgtacatg atggccatca
    13981 caaatcaatt cagaaaagac atgttctaaa gataataacg cacccaccat acctggttcg
    14041 cgatgattca atccacgcat accattgaaa gcatggacaa atacacttgc gcctgcttca
    14101 acagcttttt gcgcttcttc tagtgtagca ttactgtgtc ctagagaaac aactactcct
    14161 tcttcagtca cttgtttgac aaactcttct acaccttgac gttccggtgc taaagcaatt
    14221 tttttgatta aaccacctga agcttcttgc cattcatgga aagtatccaa atcaggatcc
    14281 ccgaaataac ttgggttttg tgcccctttg tgttcttctg tgaagaaagg accttcaaaa
    14341 tagattcctt tgattttagc tcctggtgct tcctgataca ttttgccgat tgtctcagct
    14401 acatctttta aacgttcttt gcttgacgtc aatgttgttg gtaaaaatga agtcactcca
    14461 caagataaca gaccttcaga catcactttg atgccttctg catcattatc cattacatca
    14521 tgattcatat agccgtgaat atgtgtatct accaaaccag gagcaatcca tttgccgctt
    14581 tggtcaatga tgttgacttc tccctcaggt agttctttgg tgtattcacc aaaaagtcca
    14641 tcggtaattt caagatagcc tgcatgtttg acacctgacg ctaaaaagaa tttgtcagca
    14701 tagataaaag ttctcattct attctctccc tttgtttttc tacctctaaa gtactcttat
    14761 ttagagaaga agtcaagaat ggtctacacc atttacaaat tttttgaaat ttgtttcaca
    14821 gcttgtgcta agccttcata gaatgctgct ctttctggtt cttctttacg cttgtatatt
    14881 aagcttttaa gcacaaataa atcattgagg taatagtagc tattcttctc ttgagcccaa
    14941 tagattcctt gattcacctg ttctaacgct tcgtcgattt cattttgatg gaataagaaa
    15001 tttccataat tataaaaaat ttgcgaaaat tcactttttg atcgttcatc agctgattga
    15061 tgcagcagtt ggatgcttcg actcaaatag tagcgtgctt cagccgtttt tcctgccaca
    15121 ccatatattt ttccgataca actaatcagt tgtatttctg tgtcagaaac atggattctt
    15181 tctttttggc tagagtagct taatgcttct ttcaaataat aaagggactg agagatattt
    15241 tgacgcaacg tgaattcgca aacaccgaga taataataat agcgttgaaa gtcagttgct
    15301 tgatacagat tttcagaaat atcagaagat tttagtactt gttctaactt ccgataatca
    15361 cgtttttgga aacaactatc caacagttca aataatttat cgtttgtccg agtagttttt
    15421 cgagagagat tcatcacatg atcaatcgtt acccctagcc gttgacaaat ctgcatcatc
    15481 accaatacat tcggcagttc ctcattattt tcgatccgac ttaatacact ttgtgaacaa
    15541 atatcatgcg aaagcatttt ttgcgtcatt ttttgttctt ttcgaatctc tttaatgatc
    15601 gttccaaagg actcgattaa cgtttccata agtatcctcc ccaaaatatg cgtattcgca
    15661 ttctattcgt attttacttt aggaagtcgc aaacttcaag aaaagacttg caactaaata
    15721 atatacttta gttatttaag aaaactccac tagaaagaga gcctcagtgt gtttgtctgt
    15781 ggccctccta ctgaaaaatt tggtttttaa aatcattttt ggcgataggt tgctaggaat
    15841 tctctcattt tcttagctgt ttgtttcaaa tcatccattt taggaagata aacgattcga
    15901 aaatgatctg gctggttcca attaaatcca ccaccatgta caagtagaat atgatgttca
    15961 tgtaaaaagt ccaaaacgaa tttttcatca tccaaaatat tgaatcgctt tgtatcaatt
    16021 tttgggaata tataaaaagc agcttttggt tttacggctg aaagaccagg aatatcattg
    16081 attgcattat agatatattc tctttgttca tagatccttc cgcctggcag gagcagctca
    16141 tcgacacttt gataaccgcc tagcgcggtt tggataattt gctgagacaa tacattggaa
    16201 cacaaacgca tggaggacaa catattcagc ccttctatat agcctttgac gtgtgactta
    16261 tctccactta ggaccatcca gcctactcga aatcctgcta cacgatgaga tttggataga
    16321 ccgttcagcg taacaacgaa caaatcaggc gctaatgtag caatcggaat atgttctaga
    16381 ccatccatca ctaagcgatc atagatttcg tcggaataaa taatcaggtt attttgtcga
    16441 gctacttcaa cgatttcttc taataattct tttggataaa gtgccccagt aggattatta
    16501 ggattaatga taacaatagc ttttgtccga ctcgttattt ttgatttgat atcatcaata
    16561 tcaggatacc attctgcctc ttcatcgcaa atataatgaa caggtgtgcc tccagctaat
    16621 gcaatagaag ccgtccacaa cggatagtcc ggcattggaa ccagtacttc atctccattg
    16681 tccagcaacc cctgcataca catcgtgatc aattcgctca ctccgttgcc ggtgtagata
    16741 tcattgatcg tcacattcgg aaaatgtttc agttggcaat attgctcaat tgcttttcta
    16801 gcagaaaaga tccccttgga atctgagtag ccttctgagt cacgggcatt catgatcaaa
    16861 tcacgaatga cttcgtttgg tgcttcaaat ccaaaaggtg cgggatttcc cgtgttcaat
    16921 tttaaaatac taatgccctc ttcttgcatc cgctccgctt cttctagaac gggaccgcga
    16981 acatcgtaac tgacaccttc taatttgttg gatttttcaa attctctcat cacttagcca
    17041 atccctcatt tcaaaaagtt agaactttcc aaattttttg ttatttacta tttcaatatc
    17101 atactccatc ctagaaaatt ttgccactta tttaggaaaa acgtaagtat taaaaaaaca
    17161 caaacaagcg ttgagaactt aattgtcatg atagtcattc catagattcg ctgcccaatc
    17221 cattgcaatt ccacaaatga ttcctagcat aaaaccaagc aaaaaacgtc cgaatgcaag
    17281 tccaatcaat acacctaaga tcattcccag tcctgaaaat tctccgtcat atttctccat
    17341 cttaataagt cctcccattt ttgagcttga caactatgta aaacctcgct atcattagtg
    17401 tgttattatt acgcagatgt gttggaattg gcagacaagc atgattgagg gtcatgtgag
    17461 cgttagctcg tgtgggttcg agtcccatca tctgcactac aactcgtgaa gttaattttg
    17521 cttcacgagt ttttttgttt gaacgtttct ttatgccatt atatacatat cactgtatcc
    17581 tttacaaaaa gaacgtacaa tcatgtaaac agcctgaggt gagtatatga aggtcggaaa
    17641 caagctactc gtagaaactt gcaagtgtta aaacaattaa tcgaaaaacg agtaaaatcc
    17701 ctcacctaat actaaagcga gggatttttt gtatattatc tgtttatcac cgttattata
    17761 aaggtacaaa taccaagcac ggttaatcca aattgcataa attcattttt ttgtacactc
    17821 atgcttttca ttagctcttt aactgccatt agtactaaga tggcgataac aacataaagt
    17881 atatagtacg tccgcattcc ggaagcccat actgtgggag aaaatcccat aattaacctt
    17941 gaacaaaatc ccattatcat caaaataact aaaaaaatag aagttttctt attgtcaaaa
    18001 cttaaataaa ttccaacaat taaacatagt aataatgcca agactactaa agtagctatc
    18061 caagtacctg gataaaaaag tgacagtttc gttcctaact ctgtaaagag attattcagg
    18121 ttactactac tccaaatcat tgccctttta tttccattga cgtaagtaaa gctttgaccc
    18181 attgtattac caaaataaat aatcaggttt aagaaaaacg gtaatgcagt caatatacgc
    18241 acataatagt tttgacattt cctatatgtt agaaggaaaa ttaagaaaaa tagcaataaa
    18301 aataagatat tcatgtctaa aa
//
LOCUS       DAFEML010000047        17355 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFEML010000047
VERSION     DAFEML010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.048"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            167..796
                     /locus_tag="LP468_001916"
     CDS             167..796
                     /locus_tag="LP468_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081430.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(920..2029)
                     /gene="ugpC"
                     /locus_tag="LP468_001917"
     CDS             complement(920..2029)
                     /gene="ugpC"
                     /locus_tag="LP468_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL2081431.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            2238..2660
                     /gene="mgsA"
                     /locus_tag="LP468_001918"
     CDS             2238..2660
                     /gene="mgsA"
                     /locus_tag="LP468_001918"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL2081432.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            2983..3519
                     /locus_tag="LP468_001919"
     CDS             2983..3519
                     /locus_tag="LP468_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2081433.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(3559..5322)
                     /locus_tag="LP468_001920"
     CDS             complement(3559..5322)
                     /locus_tag="LP468_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081434.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(5325..7040)
                     /locus_tag="LP468_001921"
     CDS             complement(5325..7040)
                     /locus_tag="LP468_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081435.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(7819..8043)
                     /locus_tag="LP468_001922"
     CDS             complement(7819..8043)
                     /locus_tag="LP468_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081436.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            8234..11011
                     /locus_tag="LP468_001923"
     CDS             8234..11011
                     /locus_tag="LP468_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2081437.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11092..11511
                     /locus_tag="LP468_001924"
     CDS             11092..11511
                     /locus_tag="LP468_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL2081438.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            11523..11993
                     /locus_tag="LP468_001925"
     CDS             11523..11993
                     /locus_tag="LP468_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081439.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            12010..12789
                     /locus_tag="LP468_001926"
     CDS             12010..12789
                     /locus_tag="LP468_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081440.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            12776..13597
                     /locus_tag="LP468_001927"
     CDS             12776..13597
                     /locus_tag="LP468_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081441.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            13614..14663
                     /locus_tag="LP468_001928"
     CDS             13614..14663
                     /locus_tag="LP468_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2081442.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            14676..15680
                     /locus_tag="LP468_001929"
     CDS             14676..15680
                     /locus_tag="LP468_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2081443.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            16313..17332
                     /locus_tag="LP468_001930"
     CDS             16313..17332
                     /locus_tag="LP468_001930"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2081444.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         5569 a         3046 c         3527 g         5213 t
ORIGIN      
        1 tttgtcacat ctcctatttt tgtttcttga tcaaaaaatt cttatacttg atactcacac
       61 tcattttgta tggatttaga aaagaatatg tgtcttgaca gttattagta agtgagttat
      121 actaagtcga catttatgtg tcaagacata ttaggagaga gaaaaaatga gaaaaaattc
      181 agttcgaaaa ctaacgattt ctgctttatt gattgggatg ggggtcatta tcccaatggt
      241 catgcctaaa atcatgattc caccagcttc ctttactttg gcgtctcatg tgccattatt
      301 tattgcgatg ttttttacac caggagttgc agtggctgtt gcgctaggta cgacatttgg
      361 tttcttttta acaacgccgg ttatcatcgc attgcgagca ttgtcacatc ttgtgtttgc
      421 gttgattggg gcttggtact tgcaaaagca tccgagtatc gttttaaaaa atggacagtt
      481 tacttttgct aattggcgtt tccaagggtt caattttgtg atcggtgtga ttcattcttt
      541 agcagaaatg ctagtagtca gcatctttta ctttattggt aatatgcctg aaacatatta
      601 ttctcaagga tatttttata cagtattcat cttgatgggg attggtgggc ttatccacag
      661 tttagttgat tataatattg cttattttat agcaggaaca ctcagcaaat attttgatat
      721 ccccgtattt acggcagcaa aaaaagaaaa tcggaaagag tcgattcaag ggtacgcgaa
      781 gaaaacgaca tattagacat gatctctcaa aaaaaaaact ctcatctagt aatggataat
      841 aaatcctcta agatgagagt tttttgtcct aaaaagagct gcaccaacat cttctggcac
      901 agctctaaca gggggcaatt tatggaagtt tgatgacttg ttctgtttct ttatcaaaga
      961 agtggccttt gctgatgttg aaggcaaggt cgactatttc gcctggttta tggaaatctc
     1021 ttgcatctac ttttgagatg aactcagtag aaccagtttt tgtgtaaagc atcgtttcag
     1081 ctccaagtaa ttcggaaacg acaacttctg atttcactac ggcttcaggt gaagcttcaa
     1141 gggctacttg ttcactgtgg atgtcttctg gacgaatacc gaagataact tcttttcctt
     1201 cataaccttt ttcaactaat actttgtttt ttccttcagg aatacgaagc ttaagcccat
     1261 gtccatctgt gataacacca tttttcaatg tcacattaaa gaagttcatg gcaggagatc
     1321 caataaagcc ggcaacgaac atattgacgg gtgtatcata aacttctttc ggtgtaccga
     1381 tttgttggat aaatccgtct ttcatgataa cgattcggtc agccatagtc attgcttctg
     1441 tctgatcgtg agtaacatag atggtcgttg tttcaagacg ctggtgaagt ttggcaatct
     1501 cagcacgcat ggctacacgt aatttagcat ctaaatttga taatggctca tccattaaga
     1561 agacttttgc atcccgaacg attgcccgtc ccaatgccac acgttggcgt tgtccaccag
     1621 ataaagcagc tggttttcgt ttcaagtatt ctgtcagacc taagatctct gctgcattgt
     1681 ccacacgttt tttgatgtct gctttatcat atttacgtaa tttcaagcca aaagccatat
     1741 tatcaaaaac agtcatatga ggatacaatg cgtagttttg gaaaaccatg gcaatatcac
     1801 ggtctttagg tgccacgtca ttcatgactt ttccgccgat atttagttct ccttcagaga
     1861 tatcttccag tcccgcgatc attcgcaaag tagttgactt tccacaaccg gaaggaccaa
     1921 caaaaacgat aaattcacgg tctttgattg atagattaaa atcagttaca gaataatttt
     1981 ctgcattgtc atatttttta tatacgtttt tcagagccat ttctaccata atacgttcca
     2041 cactttcttt tttagtttta ttaactattt aaagtataaa tgaaagcgtt aactaacttc
     2101 aatgtcatgt tgaacaagaa ttttttcttt tttttgtcaa tgtgctagtt ttaagcttta
     2161 ataaatatcc ataagaaata aaaactgata cactggagta aataagtatg ttaacaatat
     2221 caaaaggagt gtctcttatg aaaatcgctt tgatcgctca tgaccgaaaa aaacctatga
     2281 tggtgaaatt agcaacagcg tataaaacaa tattggaaaa acatgaactt tttgctaccg
     2341 ggacgactgg gcagaggatc acggaagcaa ccggcttgcc gatccatcgg tttaaatccg
     2401 gaccgttagg cggggatcag caaattggag ccatgatttc ggaggatcag ttagatttgg
     2461 tgatttttct tcgagacccg ctggctgcac agccccatga accagatgta acagcactta
     2521 tccgtttatc tgatgtctat gagattccgt tagctacgaa tatcggaaca gctgaggtgc
     2581 tactaagagg actggaagcc ggcttcctag attttcgaag aatcgtccat gaaatagaca
     2641 agcatccact ttcattttga tggataagcg tgtggaaaaa taacgtttaa tgttcgccta
     2701 tatgtagcta taaaagctaa acaaactgat aatatgcgat ataatacgaa cgtattggat
     2761 aatataaaca ataatattag tttttcgtat ttgcagtaaa tgtgaaaata tgctatagtt
     2821 tctgtgggaa aagatcccaa aaataataca gagtagaaaa taaagcgtta agtgctaaga
     2881 ggatgggatg ttgcctcttg gacgaaggac gtaatgttcg cggttttatt ttcgcattcg
     2941 ctgcatgata cgatgtagca gctcttaaag gagatgctaa aaatgaagaa acaccggtta
     3001 gacgcacgta tgattgctat tatgggctta ttgattgcat tgatggtcac tttgtcccga
     3061 ctggtagcaa tcgagacccc atttattaaa atcagtgtca catttattcc acaagtgatc
     3121 atgggcattc tttttggtcc tttttggtca gggataggcg cagttttagc tgatttagta
     3181 ggaatggccc tcttctcgaa atctgcattc tttattggat ttacattgaa tgcatttatt
     3241 gaaggagcaa tctacggatt ctttttctat cgaaaagaga tcacttggaa aaatgccatt
     3301 ctggctacgc ttagtgtcac gctgatcatc aacttatttt tgacaccatt atggcttgcg
     3361 ttgatgtacc atgtgccatt gttcagctgg gtcgtttggg cgccccgcct gttaaaaaca
     3421 gtaatatggt taccgattca atcaattgcc atttattacg taggacgtag tattccttac
     3481 aaaaaaattt taagaagttt agcgatccac gctaaataaa aaacaagcag tcttcccatc
     3541 ccagaagact gcttgttttt attgtgctgt gaattgtgct tgatagagcc gtcggtaata
     3601 accatctttt tgaagcagct catcatgggt gcccatttcg acaatagctc cctgatccat
     3661 cactaatatc tggtccgcat ttttgattgt ggacaggcga tgggcaatca caaaactggt
     3721 ttttccttcc atcattgcta agaaggcttg ttggattttt ttctctgtca atgtatcgac
     3781 tgagctggta gcttcatcta agatcaacat agggggatta ctgatcatcg ttcgagcaat
     3841 cgtcaacagt tggcgttgtc catctgatat ctttaaccct tgaccgccaa tcttagtatc
     3901 taatttttcc ggcaaacgtt ctacaaattc atacatataa gaggctttta gggcatcatt
     3961 gatttctgcg tcacttgctt ccggattccc aaaacgaaga ttttctcgca atgtactgtc
     4021 aaatagccaa gtatcttgta acaccattcc aaaactttta cgtaatgtat cacgttggat
     4081 agagcggatg tcatggtcat cgactgtaat tgttcctttt gttgtgtcat aaaaacgcat
     4141 cagcaaatta acaagtgtgg attttccggc ccctgttttt cctactatag caatggtttg
     4201 acctggataa gcagtaaaat tgaaatcttc gatcaaacgc tgcttggggt cataagaaaa
     4261 agaaacatga tcaaaagaga cttttccttt gatatttttg ggttccaagg cataggcatc
     4321 tggcaaatca ggcttttctt ctggctgatc gatcaaatca aatgctcgtt ctagaccaga
     4381 aaaagcggtt tgcagttgtg tcgtgattcc agaaagttcg ataaatggtt tagaaaactg
     4441 acttgagtag atcgtaaagc tggaaatcac accaacagtg attgacgaac cactcttcaa
     4501 tgccaatagg ccgccaacta aaccaatcga taaataagca aggtgatcta caaaacgaga
     4561 agacgggttt gtcaaggaag aagaaaattg tgcccgttgt cctttttcat atagatcagc
     4621 atttagcagt tcaaattgct gttgactagc ttcttcttgc tgaaaagctt tcacgatttt
     4681 ctggttaccg attcgttcgg tcacaaagcc cgagatatcc ccaataatcc tttgctgtct
     4741 atcgaaattt gtttgtgaag cacgagcaac gatccaactc acaaggaaaa taattggtgt
     4801 agaacaaaga acgaccaatg tcagaagtgg acttagacgc atcataaaaa taaacgaaag
     4861 aatgatgatt gccactccag aaaataattg attgaaggcc gcagaaattg caatggaaat
     4921 attgtccata tcatttgtaa atcgactgac gatatttccg tgggagtttt gatcataata
     4981 acgaagtggc aatcgattca gatgagcaaa tgcatctttt cttaattttg caacggataa
     5041 gtaagctaac cgattgctta acacttggat gagccattga ctgactacgt tgattaaaac
     5101 gataccaccg aatagaataa gtaaatggaa cagtcgattg aagcggacct gtccttctcc
     5161 aatcatttga tcgatacttt gaccaatttg taacgtcatc acaactgttg caatcccatt
     5221 gatgattcct agtatcacag ctagccaaat gtcttttgca taggcagtaa ggtaaggaat
     5281 gaatcggcgg agcgtctgca aggataattt ttttactttc ataactattc ttcctcctgt
     5341 gatgcgacga tttcctgata ttctgctgat tgagcaagta attcttcatg ggtaccctga
     5401 gcagcaatct taccttgatc catcactaag atatgatgtg cttcttgaat agagcggaca
     5461 cgttgggaga taataatcac tgtactgcca agataagtct gtagcgcctt acgcaaatcc
     5521 aagtctgttt gataatccaa cgcacttaaa gagtcatcta aaatcagtaa tgctggcttg
     5581 gcaatcaaag ctcttgcaat cgtcagtcgc tgtttttgtc cgccagagaa atttttccca
     5641 ttttccatga cttttgtatc taaaccattt ggaagctgac ggacaaattc ttctgcctga
     5701 gcgattttca gagcttccca acattctttt tctgtggcgt ctttcttacc ccattgaagg
     5761 ttttcacgaa tagtcccggt aaatagtaca gaagtttggg gaacaagagc aatttgctga
     5821 cggagatgat ccagctgcca agaacgaaca tccattccgt ccattataac tgtaccggaa
     5881 ctgacatcat agaaacgcgg aatcaattgt gtcaaagtcg ttttcccgct tccggttgga
     5941 ccaatgattc caaggactgt atttcgcttc agctgaaatg taatattttg gagagaaaga
     6001 ccagaatcag gagtataacg gaagtcaaca tggtcaaaag cgataattgc ttcagaagaa
     6061 aaatcgggag tagtactgac ctcagcttca agaatcgaat tttctgtgtc tagcacctct
     6121 ttcacccgat ttcctgaagc ttcggcacgt gtgaagatca cgacgaggtt tgaaacaacg
     6181 atcagtgcca aaagcatttg attcatataa ttgatcaaag caagaacttg tccttgttgc
     6241 aagctaccaa tatttacttt gatcccgcca actgtcagca aacagatgat cccgacattc
     6301 atgatcaagg ttgtagcagg tgataatagg gcagagatat tggaaacacg taaataattg
     6361 ttcgctagat catttgtgct tttatcgaac ttctctgttt ctttttttgt ctgcgcaaat
     6421 gcgcggatga cacgaacacc gctaagattc tgactaacgt gttcattgag ctgatctagt
     6481 ttttcttgca ctttttggta gagaggaacg gtttttttga tgataaaaaa taaaatgatt
     6541 gagaaaatag gcaataatgc taagaaaaac agacctactt cccagtcgat cacaaaagcc
     6601 atgaccactg acccgatact taaaaacggt gctctgatca ataaacgaat gaccattgct
     6661 aaagctagct gaagctgatt gatgtcgttt gtcattcggg tgatcaaggt atctgttcca
     6721 aaatgattca actcgttgtg agagaaagta ttgatttttt tgattagctg attacgtaac
     6781 tctgtaccaa atccttgtga agctactgaa gcatagtatt ggcaaatgat agcacaaatc
     6841 agaccaatca cagacatagc gaccatccat aagcccattt caatgatttt tcctcggtca
     6901 ttcattttta gtccattatc gatcaaggaa gccatcatta aaggcaggac aagttcgaag
     6961 acagcttcaa gaaatttgaa gaacgggccc aaaatgattt gcttacgata gtcttttgca
     7021 taacgtaata actgaatcat atgattcctc ctattattta tttgtccaca attgaaaaaa
     7081 caagtactac cacattgtag cttaggaaat ttagaatgaa aagagaacaa gccttttcat
     7141 aaatgaaagt tttattatga agaagcttta gaaattgaat agactatttt ttttaaaaaa
     7201 aagaaaatga gaaaacatgc cagtctcttc attcatagga acgtctattt tacttaattt
     7261 ttctataaat gaattctgca taaaaaatat atcaagtaaa tgtttataga tgaaactcta
     7321 tttacttctt ttttaatttg ttcttgcaat cttttttgct acgtaatttt tgtaaaaaag
     7381 tgggttgaga gaaatctaat tgattttcaa agaaggagta tgaaaatgag aaaaatattt
     7441 attcgtttat tgtgggtact atcttagagg aataaataat agtggagaaa actatggttt
     7501 ggcgcagatt ctatcaggtt tgatggaacg aagacaacct cccgacatca agtcaaaagc
     7561 tacttgagat tttgatctga aaataaaaaa agaaaacaag gtaggaacat caatgtttct
     7621 accttgtttt cgtaatcaat gggaaaaaac taagagtggt gtacgtaatc aataaaaagg
     7681 atggtgacaa cagtacctct ttactctctg aaagcatcat aactcgtttt tcctcattat
     7741 gccaataaat tgttgttata ccacatataa ggatttgtaa tagctaaaaa cagacaggaa
     7801 agttgaaatc tgtgaatctt attttgtatg gaaggattta tagaacgcaa aaatcaagat
     7861 aaagatgaat aaaaatcctg tttcggctat atattgcgta tctacgccaa taaaacgagt
     7921 ttgttctgtc atagccatat aaagcaaagg caaaaataca actacagcga gataagatcc
     7981 gatgatttct cgaaaagttt tccaggaagt atgtttcctg tttttatatt tatccgattt
     8041 cattgaatag tcatagcctc cttattcttt catatgttga aattccagta taaaaactgg
     8101 aaggaactgt acgtttttta gaataaaaat tataagggat aagtaggctg ctgtctataa
     8161 taagatatat ttttcaattc tttattaaag attttattga caaaatgaat ccgttttcta
     8221 tgatggagga ggggtgaata agttgttgaa gaaggaaatt ttatgttact tagagaacca
     8281 gacagccttt ttcgatttag aacatatgaa cgaggtcttt acagcacaaa ggttagctga
     8341 tcattttggg gtaaaaagaa acacagtcag tcattatttg aaccagttaa atgatgagca
     8401 actactagtc aaaatcaatt ctcgaccagt gatttatttc cacaaagaag cttttgaaaa
     8461 acaatttttt aagttacgca cgaattttta tttttctatc gatgatctca aagaggaaca
     8521 gccttttttc gcgcaaccaa aagacttatt ctcttttatg atcggatacg acgccagttt
     8581 gaaagaaagt atcgaacaaa tcaaaacagc tctttactat ccagatggcg gattaccact
     8641 tttgattaca ggcgaaagtg gcacaggtaa aagttattta gttaatttgg tctatcagta
     8701 ttgtctgctt catgatctgc tagaagattc tgcaccattc atcactttta attgtgcaca
     8761 atatgcagat aatcctgaac ttttgactag caatttgttt ggacatgtta agggagcgta
     8821 cactggtgca gaagaaaata aaaaaggggc ttttgaagca gcagatggtg ggatcttgtt
     8881 tttagacgag gtacatcgct taacaccaga aggtcaggaa aaactgttca cctatcttga
     8941 tcaaggtgtg atttatcgta tgggagaacc taatttgtca cgccggatca aaacacgtct
     9001 cttttttgct acgactgaag agattactag tcatttctta acaactttca ttcgaagaat
     9061 acctatccga atcgaactac ctgcacttaa tcagcgtagt cgtaatgaac ggctagaact
     9121 gatttactct ttttttctcg aagaacaaag aaaaatgggg agccctttgt cagtcagtgg
     9181 accagctttg tcacttttaa caagtcagaa attatccgga aacataggag agctgaaaaa
     9241 tatcgtcaaa gtttcagcag caaaagcata tgctgaacag cgtgaacagc ctgaaatcca
     9301 tgtcacgatc catcatttgc aaaaagaact acttgcgcag cctattacta aaaatacagc
     9361 acagcaagga atctatatta cgcaagacca gaccttagag caattaatgg agaagcaaca
     9421 gcccgaacag cagcgaatcg ttaaaagttt tgagcaaatc ctaattgatt tcaagaaaaa
     9481 taactgtctg ctatattctt gcgaaggaaa attaaagcaa gaagtgattc aattatttga
     9541 ttttttgctg tttgagacca gtagacaaga aaaacacgag ctgctggttt attggacaca
     9601 atctatccga gagacctttc gacaaatgga aactgcctat caaatcaaat tcgatggaaa
     9661 cagtgtctat gccttgagtt actatctcta tcagcgaagc actatcaaat ggttaccgga
     9721 agaacatgat attatccaac taatcaaaga attagaacaa caagtttctc agtcttatcc
     9781 atctagttat cactatgtcc aacgaattct ggaattaagt aagatcaaat tagatattga
     9841 agacacaagt atggatcgga ttttactgac gatctatcta aaaaaagcga aatggtcaaa
     9901 agaaaaacga ctgccaaaag cgatgattgc tgctcacggt tatgcaactg ctagcagtat
     9961 ggcaaatgta gtaaatcgtt tattacaaga ggatctattt gaatcatttg atatgccact
    10021 agatgtcaca ccacagcaga ttgcttcaga aatccttgat tattgcgaaa acagcgatgt
    10081 ttcaaatgga ttgatcatat tagtagacat gggatctctg aaagaaatcc atcagttttt
    10141 taaaaaacag ttatccgtac cgcttttgat tttgaataat gtgacgacac ctttagcaat
    10201 cacagtaggg gaatgcctgc aaaaaaatgt atcattagaa gagatagcag aagagactgt
    10261 tcgacagatc cagccagaat ggcgactgct ctatccagag gaaaacaaac ccaaagcact
    10321 cattactact tgcttcactg gaatcggtac ggcggtccac ttaagtgaac tgctagaaaa
    10381 aagcttacct acggcttgtc agttgaaaat catcccatat gaatatcagc aattaaaaga
    10441 taagaaaaac agtgacccat tattttccat atacgaagtc gtaggaatga ttggcaccac
    10501 agatcctgat atcaccaata tcgactatct ttcattagaa gacctcatct cgggggaaaa
    10561 gatgtctgta ctagctgaat ggttggacac tactatgaat gcttcagaga aggaaatatt
    10621 caatcagcgc atcattcgta atttttcatt ggaaaaagta ctggattccg tgactattct
    10681 agatacagag aaggtgatgg gagaaatcga tcattttatg agagaattag aggtgcagtt
    10741 gaatcgaagc atcagcaatc ccaaaaaatt agcgttgtat gtccatgtga gctgtctcat
    10801 tgaacgattg atccgacaaa tgccaatcga aacctatcaa ggattagaga aatggaagca
    10861 gtgtcaaaaa gaagggttat ctgctattaa atctgcgttt agtgtcattg aagagcatta
    10921 tagtgtcatg atccccaatt ctgagattgc ctatatctat gatattttga gtgaagatac
    10981 agagtttctc tcgatagaag aagaattttg aacataagca agttgttgcc actaattttg
    11041 gcatgcaact tgctttttta gtatgtgtaa gtgaaaagag gagatgaaaa agtggataga
    11101 gaaattatct tagcttccca tggaaaattt gcttcaggga tattagattc attagagctg
    11161 atctatggga aaaatcattc tattactgta ttcgattgct atactgatga gaattttgat
    11221 ttagcggaaa cagtaaggca gctttttatg aggtacaaag ataaagaaat cattgttctg
    11281 acggatcttt ttggcggaag tgtcaacaac gaattcttac aatatatcaa tcgggatcat
    11341 gtctatctcg ttgccggatt gaatttgcca ctattgattg agctagtatc tcggttggac
    11401 gctgaagtag agacaactgt tttgatccag caggtgctaa ctgattcaaa aaaaatgatc
    11461 cagttttgta acgagcggct caatcagaaa atagaagaag acgaatttta ggaggaagaa
    11521 aaatgattgt attgacaaga gtcgaccatc ggttattaca cggacaagta gctttttcat
    11581 ggacacaaac aataggcgca gactgtattt tgattgctaa tgatgatgta cctacgaatg
    11641 agatacgaaa gacaacgatc aaattagcca agccacaagg agtcaaacta gtgatcaaat
    11701 caattgatga ctcgattgcc gcgttgaaaa gcggggtgac agataaatat aagttattca
    11761 tcgtagtgga atcgatcgag gatgcatata agctggcaga agcgtatcca gaaatcaaaa
    11821 ccatcaactt aggagggatc aaggcaaaac ctggtactcg cagcatcgga aaagcggtaa
    11881 atattttacc agaagaggag gaacgcttga aacgattaat tgacaaacaa atagaagtag
    11941 aaatccgtca agtaccagca gataaaaaag tggatgtaag agaagttttg taagaaagga
    12001 agaacctcaa tgattgtaca agcagtctta ttaggaattg ttgcatttgt cgcacaatca
    12061 gaatatgcac tagggacatc gttgctttct cgtccgattg tgacggggct gtttacagga
    12121 atcgtgttag gtgatgtaaa aactgggatc attatgggcg caactttaga gttagcattt
    12181 atcggatcgt tctcagtagg tgcttcgatt ccacctgatg ttgtgaccgg tgggatttta
    12241 gggacggctt ttgctattac agctggagcc ggtacagaaa ccgcgctttt actaggtttg
    12301 ccgattgcta cgttgacatt gatattgaaa aatatttact tagggctttt gattccaatt
    12361 atgaaccata aagcagacaa ttatgcagaa gaaggaaatt ataaaggagt cgagcatatg
    12421 cacttgcttg ccggtatcgg tctttccttg atgcttggtg ttgtggtaat ggtttcttat
    12481 atggtgggaa gcaatacgat cggaaatcta ttaaatatga ttcctgactt cgttcaaaag
    12541 gggttgtcag tagctacagg gttgattcca gctcttggtt ttgcgatgct tgctcgtttg
    12601 ctgatcaaca aacaagttgc accatatttt ttcttaggtt ttgctatagc ttcttactta
    12661 gagattcctg tgaccggagt agctattttt ggtgcgattt tagcagttgt ggtagtcaat
    12721 attatgaatg tccgtcaact accacttcaa acaactgcag gggaggtaga agaagatgaa
    12781 gaattctgag atcaaaaaca gcaaaataac gaaaaaagag ctaaatcacg tattttggcg
    12841 ttcttttcaa atggagtttt cttggaatta tgaacgtcag atgaatatgg cttatgttta
    12901 tgcaatgatt ccgattttga aaaagttata tcagtcgaaa gaagaaatgg cagcagcttt
    12961 gaaacggcat ctagagtttt ttaacacgac cccacatatc gttacactga ttttaggaat
    13021 cacggctgca atggaggaag aaaataagga tgatcctgaa tttgatgtga ctgcgatcga
    13081 tagtatcaaa acatctttga tgggacctct tgcagggtta ggagattctt tcttttgggg
    13141 aactttgcga ttgattgcca caggtgtggg tacctcttta gccatgcaag gaaatatttt
    13201 aggccctatc ttgttcattt tgattttcaa tattccgcac attctgtttc gctatctagc
    13261 aacaggttgg ggatatcgct taggaacggg ttttttgaaa aagatccagg caaacggtat
    13321 gatggaaagt ttgacattag gcgcgtctat tattggactg atggtcgttg gagcaatgac
    13381 tgccacgatg atcaccatca atattccttt aaaaatcggt tcaggagaaa atgctgtgac
    13441 tgttcaaagt atttttgatg atatcgttcc aaatatctta tgtcttggag catttggcat
    13501 agtgttttat ctattgaaga aagaagtgaa accattaacg atcttgatcg gactagcttt
    13561 ctttggaatt tttggttcgt ggatagggat tttttaaaaa aggagcagag aaaatgttta
    13621 cgatgcaaga ttatatctat gaagaaaagg aagtactaag tacgatcttg aaaaagaatg
    13681 atttttcgac aagagaacat atgaaaaaaa cagtgaattt actgatctta gcaacgggtt
    13741 catcttataa cgcttgttta gcagcgaagc cagcattgga atcttatggt gatcttactg
    13801 tcgatattca agaacctttt tattttttca attatggaaa actttctcct tcaatcgata
    13861 ctgtgattgc tgtgtcacaa agcgggaaaa gtgcttctac tgttgaagca gtaaaaatga
    13921 tacaaaaaca agggttacct gttgttgcta tcacaaatga cgtgcaaagt ccacttgctt
    13981 tagaagctgc acaaattatt gatttaggtg ccggggtaga atcagtaggc ttcgttacaa
    14041 aaggctattc tgcgactgtt ttacagttac tactcttagg gataggaatt ggaataagta
    14101 aaaataaaat cagcaaaaaa atagaacaag actacatgca acagttgcgc aaaataatca
    14161 accatttacc agcgattatt caaaaaacgg aagaattttt tgatggatat caaagtttat
    14221 ttcgtttagc acagcgtttc gtcaccattg gatatggtcc aaactgggga acagctaaag
    14281 aagcagagac gaaattgact gaaacaatcc gcgttccgtc acaaggattt gagttagaag
    14341 cttatatgca cggcccatac ctggaggcag atgcttcgca tttgctattc tttattgaag
    14401 gggaaagtgt aaataaggaa cgttcgcaaa agttgcaaag atatatgagt cggtacgttg
    14461 gagagactct caccattacc acaaaaaaag caagaaacga gaaaacactt ggattagcaa
    14521 tagaatgtga tgaatatctg tctgtattag cgcttgtcgt tccgtttcaa ctattcgctt
    14581 ataaaaccgc agtagctaaa ggtattgact tgaacaaaaa gatttttgaa gactttgata
    14641 cagtcttgaa aagtaaatta taagaggtgg aaatcatgct gaaattcaat gaagaagaac
    14701 aaatcaaagc aataaaaggc gcactagctt tacgtccgca agtagaagaa atcatcgata
    14761 aactttatgc ggaaaaattt gacgctgtct attatctagg aatcggtgga acgtatgctt
    14821 cctcgatgca agctgtcact tatatgaatg ggaaaagcaa cttgcctgtc tttgtacagc
    14881 atgctgcaga atattacact actggaaaca aaagattaac aaaagattct atcgttattt
    14941 tgtcctctgt taccggtaca actcaagaag tagtgaaagc agtagaacaa atcaagaaag
    15001 taggagcgac actgattgga tttatcgata aagcgaacag taagttgtct cagctatgcg
    15061 attttgtggt cacttatcca gctcctggaa cagaacaaat caaatttttt atggcagcag
    15121 atcgattgat gtatttgaat ggagaattcg aagcttattc agaatactat gaacagctcg
    15181 aacgttattt accaacaggg ttagtggaag cagagaaaaa agcagatgca tttggcttat
    15241 catttgcaga aaaacatcga cgtgatagta tgcattattt tattggagca gggaatcaat
    15301 ggggagctgt ttattcatat gccatgtgtt actgggaaga acaaagctgg cttccatcga
    15361 aatctatcca tgctgccgag tttcttcacg ggacgttaga gatcgtagaa gaaacaaccc
    15421 cagtcacatt atttttaggc gaagatgaac agagagtgtt atctgaacgt gtggctaaac
    15481 ttttgccaaa aatttgcagc aattatacat tgatagacac aaaagactat ccagtagaag
    15541 gtatcagtga aaaatatcgc ggacgtgttt tgtctttctt attgatgcat gtagtgacac
    15601 aacgcatcga tgctcatgtg gagcagttga actgccatcc attagagata cgccgctact
    15661 atcgtcagtt tgattattag gatagactgg ataaaaagaa tataaaaaat aaagagagca
    15721 gcgataactg ctccctttat ttttttaaaa tattggcatc aattacgtta taaaacacat
    15781 tttttgcatt atctacagtt caacttataa tctgtttaat gggacatgtg ggtgccaacc
    15841 attttttgtt atgcaatagt actatttagt tgttgcatgg atccgtagta aaagtccaag
    15901 tacaacgagt tgcgccagtt tacatagcgt tttgtatcca gaatgttgac taaaacaaaa
    15961 gttcctatgt caaccgtcaa cagagacaat ctgtccgttg caggacctga cagatttaga
    16021 aatgttcaat ctgtctctta tgtattttaa atcaatactc actaggagaa gtttcctaac
    16081 ctcctaatag taatgctggt agtaacattg tcaaaactgc ttcctcttag gaacaagcaa
    16141 agcataacga gtgtaaaaat aaaatgtaga ctattgtaac atatcattga ttatttcaag
    16201 taaaaacgat aaaagaagta aacaaacact taaaaacaat ggaaattagt cccaacttta
    16261 agaaatgtat actataatgg aaattatcaa ttatttattt ggaggaatat ccatgaaaca
    16321 aaaaatcgca gttcttggtc ctggatcttg gggcactgct ttagcacaaa cattggcaga
    16381 aaacgggcat gatgtccgta tttggggaaa tgtacctgaa cagattgatg aaatcaataa
    16441 gtatcataca aatcagcatt ttttacctga tttgacgatc ccagaatcga ttatcggata
    16501 taaagaattg gcagaagcag tggataacgc agatgctatt ttatttgttg ttccaacaaa
    16561 agcgattcgt tcagtcgcac aggaacttat tggtaaaatg aatactaagc caatcattat
    16621 acatgcaagt aaaggactag aacaagatac gcataaacga atctcagaag ttttggctga
    16681 agaaattcca gaagaaaaaa gacaggcaat tgttgtatta tctggtccta gccatgctga
    16741 ggaagtggca gtacatgata tcacaacaat tacagctgca agtattgatc aaaaagcagc
    16801 agcctatgta caaaaactgt tcatgaatga ttatttcagg atttatacaa ataatgatgt
    16861 gattggcgta gaaactggtg cagcactgaa aaatatcatt gcaattggtg ccggcgctat
    16921 ccatggatta ggattcggag atgatgcaaa agcagcaatc atgactcgag gattggcaga
    16981 aatcagccgt cttggtgtcg cgatgggtgc caatcctctg acatttatcg gtttgagtgg
    17041 tgtgggggac ttgatcgtta cttgtacaag tgttcattct cgcaattggc gtgccggtaa
    17101 cttgttagga cagggacata agctggaaga agttctagaa aacatgggaa tggtcgttga
    17161 gggtgtggca acgacaaaag cagcagtaga gctagctcaa cagctaggtg ttgagatgcc
    17221 aattactcaa acaatctata atgttttgta taatggagaa gatatcaaaa aagcagcaaa
    17281 agaaatcatg ttacgtgacg gaaaaatgga gaatgaattt tctcttcgtt aaatagatga
    17341 tcaatagtta atcgt
//
LOCUS       DAFEML010000048        17005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFEML010000048
VERSION     DAFEML010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.049"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..124)
                     /locus_tag="LP468_001931"
     CDS             complement(<1..124)
                     /locus_tag="LP468_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL2081445.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LP468_001932"
     CDS             complement(228..539)
                     /locus_tag="LP468_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2081446.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LP468_001933"
     CDS             complement(541..738)
                     /locus_tag="LP468_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL2081447.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LP468_001934"
     CDS             complement(1132..2859)
                     /locus_tag="LP468_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL2081448.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LP468_001935"
     CDS             complement(2852..4045)
                     /locus_tag="LP468_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2081449.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LP468_001936"
     CDS             complement(4232..4876)
                     /locus_tag="LP468_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081450.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LP468_001937"
     CDS             complement(4970..5104)
                     /locus_tag="LP468_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL2081451.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP468_001938"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP468_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL2081452.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LP468_001939"
     CDS             complement(7235..7708)
                     /locus_tag="LP468_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL2081453.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LP468_001940"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LP468_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL2081454.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LP468_001941"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LP468_001941"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL2081455.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LP468_001942"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LP468_001942"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL2081456.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LP468_001943"
     CDS             complement(11755..12894)
                     /locus_tag="LP468_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2081457.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LP468_001944"
     CDS             complement(13203..13916)
                     /locus_tag="LP468_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL2081458.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP468_001945"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP468_001945"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL2081459.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LP468_001946"
     CDS             15105..16637
                     /locus_tag="LP468_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2081460.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDNLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LP468_001947"
     CDS             complement(16828..>17005)
                     /locus_tag="LP468_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081461.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3494 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgac aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaacttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFEML010000049        16904 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFEML010000049
VERSION     DAFEML010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.050"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..190)
                     /locus_tag="LP468_001948"
     CDS             complement(<1..190)
                     /locus_tag="LP468_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081462.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="LP468_001949"
     CDS             complement(200..1015)
                     /locus_tag="LP468_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2081463.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="LP468_001950"
     CDS             complement(1277..1720)
                     /locus_tag="LP468_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL2081464.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="LP468_001951"
     CDS             complement(1854..2192)
                     /locus_tag="LP468_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2081465.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="LP468_001952"
     CDS             complement(2180..2557)
                     /locus_tag="LP468_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2081466.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="LP468_001953"
     CDS             2781..3974
                     /locus_tag="LP468_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081467.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="LP468_001954"
     CDS             complement(4140..4562)
                     /locus_tag="LP468_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081468.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="LP468_001955"
     CDS             4957..5151
                     /locus_tag="LP468_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081469.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5642
                     /locus_tag="LP468_001956"
     CDS             5148..5642
                     /locus_tag="LP468_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081470.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5804..6976)
                     /locus_tag="LP468_001957"
     CDS             complement(5804..6976)
                     /locus_tag="LP468_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2081471.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="LP468_001958"
     CDS             complement(7182..7997)
                     /locus_tag="LP468_001958"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2081472.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="LP468_001959"
     CDS             complement(8147..8593)
                     /locus_tag="LP468_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL2081473.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="LP468_001960"
     CDS             complement(8590..9594)
                     /locus_tag="LP468_001960"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2081474.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="LP468_001961"
     CDS             complement(9634..9963)
                     /locus_tag="LP468_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL2081475.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="LP468_001962"
     CDS             complement(10089..12416)
                     /locus_tag="LP468_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2081476.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13259..13552)
                     /locus_tag="LP468_001963"
     CDS             complement(13259..13552)
                     /locus_tag="LP468_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL2081477.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13955..15133)
                     /locus_tag="LP468_001964"
     CDS             complement(13955..15133)
                     /locus_tag="LP468_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2081478.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15237..15551)
                     /locus_tag="LP468_001965"
     CDS             complement(15237..15551)
                     /locus_tag="LP468_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081479.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15658..15873
                     /locus_tag="LP468_001966"
     CDS             15658..15873
                     /locus_tag="LP468_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081480.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16173..16415)
                     /locus_tag="LP468_001967"
     CDS             complement(16173..16415)
                     /locus_tag="LP468_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081481.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16402..16830)
                     /locus_tag="LP468_001968"
     CDS             complement(16402..16830)
                     /locus_tag="LP468_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2081482.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         4926 a         3271 c         2936 g         5771 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag cgaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcatgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aaaaatcatc aaataatcct ttacacgtta ttctaaattt aatttttatt
    12481 attttattga tgtatagaaa gtttggggct ttttttctct ttttattcta aggttatttt
    12541 agtcttgtcc tttaatacaa agattttatt tttaaataaa aaatactctt tttttacgat
    12601 tattgaaaaa aaaagataaa acttgattaa ttgaagtatt gcttaaattt ggaagctatg
    12661 agggaagaat aaaagagtta ggacgggatt atctactatt tttctttgtt ttaaatattt
    12721 gttatctttg aacataaaag agaaatgtgt cgactgcagt gttgtgtccc tcatcacgaa
    12781 taaacggtgt tcaattagct gatcttgtat tcacttaaaa aatggtaaag tacgagttgc
    12841 tattccccat tttcaatttt ctaacgctca ggacaaaata ctgttttcac aacctcattg
    12901 gaataaaagc atatatattg tttcaagaac gaaatcttgt tatcttttta aagggcatct
    12961 gtccaaaatc taattttagg aggtacgttt tggtatttat tcgtacaaat aaaagagaat
    13021 tatctttatt catgtaacgc atccaattga ttttttcatg tacgctcctg gaacgatttt
    13081 actgacgatt gcttatttaa ctgcgaatcg ctcattagct tttatcatag ctatccatat
    13141 tttgaataac gttcttggct ttgtattata gatacagatg acaaaaaaag ttcaagtatg
    13201 cggtgtagaa ccaatatcgc atacttgaac ttttttcaat gagtataaat taaaacttct
    13261 aattttcaat tcccatcatc tgatatgccc gaccgtctga acttcttttg aaaaagccaa
    13321 atgtgattag ataacgtctt tgttcgacat aatcgccact agaaaatacg ttcagcagta
    13381 tcgaattaac ctctgtttct gtataagtca ctccatggtc aaagcgtttc aagacttctt
    13441 tcaataggat gtatttcttt tttgttgaac ttggtacttg ttttactttt ccatcattca
    13501 tgaatgtgtc taaaactttc atcttttctt gctccgtata agtataaacc atcttctttc
    13561 tccttttgat tctaagaata ctccatttat gttagaatat tctggatttt ttattaaagc
    13621 ggttactctt aagaaagata ttatcatagt gctctttttt ttactactac ttataggtag
    13681 atttattcta atccattatt ctcccctacc aataattaaa gaaaaaactg gatcagggtg
    13741 ttcaaattac atgctaagaa aaaagaaccc ttgaatacca agggttcttt ctcagtctga
    13801 taacaatgat taacgacgga tttctttgat acttgtgaaa agtcgttaaa gtattgatat
    13861 aaaaggattt ttattacctc tgactacata ttgactaatt tgttaaaaaa tcgtttttca
    13921 agaatcctgt aataccagtg ctttcaccgt ttttttaact ctctaaagaa ctaaaagcaa
    13981 tcagaggttt taccttttca tttgacgtta agtggcgata aattttcgaa gttgtttggt
    14041 cagtatggcc taagcgatct ttcaagactt cccagctaca gtgttccgct actaagcttg
    14101 ccattgtatg acgagctaaa tgagtatgaa atggcttatt aattcctgag cgattcacgc
    14161 accgtttgac gtgatcattt acatactctc gacgataagg aacaccacgt ttactagaat
    14221 caagatacac aaacaaatat gtttcttcta taataaacct gtaatgttgc ctcatctcac
    14281 ccaaagcctt aatcaactgt tgtagctttt ccataactag aggagttact agaactcgtc
    14341 tagcagaact aactgtctta gtagtttcaa ttcgaaaatc cttactctta cctttaactg
    14401 ccgtttgctt atagaacaga atttcatttc ttttgaaatc tatatctcca ggctgtagag
    14461 caagcgcctc gctgactcgg cagccagtgt aaaatagaac atggaaaagt acagacatcg
    14521 gtaattcctc atgaacaatg ccataattca aaaaagttct caattcatcg acagtaagaa
    14581 acttgtcctc aatattattt atggcttctt ttaaatcagt taccgttaac tgatattttg
    14641 gcattctcac agacttcatt ggattttcac ttatcaaatt ctttctttga caatatttaa
    14701 aaatcatatt tagaacttga ataagtgatt gtaaactatt tttggcatag ccaacatttg
    14761 ttccattaac gccacattcc tttaaggtaa aaagcaattc ttgaaggcac tctggtgtca
    14821 aatcagacaa ctttttatca ccaatccatc gaacaataat ttttaattgt tcctctcgct
    14881 tatcataggt tatttccttt tgttcattta acgaacggta atattggaac cattgctcac
    14941 ctacaacact aaacttgtca ttgcttgcaa caattttttt cttaagcctt tgttgtttct
    15001 ccatttccag ataagcgagt tgcgcctcac gttttgaatt aaagccacgt cttgttgttc
    15061 gatatgcttg aaagtaccat gtgatcctac cagtagaact gatttgcttc ttgaatcgat
    15121 ctgttttttc catttattga ttcctcctat tttgaaggaa cccaacaagc agaaaccctt
    15181 tggaaatctt tctatctatg tcatcattgt accgcatctt agaaagaaaa tgtaacttat
    15241 aaagatcgaa gtagtcgcaa tttttctcga tagtcattcg aatcactctt tctcatccat
    15301 tctaaaacat catcacgaaa atagtgtcct cgaatcccgt accaacaggg aggaaactca
    15361 ccaagtttta ctaaacggtt cagtgtacta tcacttatct gaaatagtcg ctttaaatca
    15421 gtatttgtta ataccagagg taaatgactg actgcaagca atttttccgt gtaatcttcc
    15481 agtttttttt gtaaaattga atagaactct atttccagag aattaacatt tgttttaact
    15541 tccaactcca tcacccttct ctctcaaaat caaaacgacc accacggtac cccttaaaat
    15601 tgtaaaaaaa cactccagta ctccatcaaa acggactaga aaagaggatt ttttaatatg
    15661 aaacaaggaa ttgcagacat aaaaataatt aaagaaattc ttgaaaaatc tacggctaat
    15721 gcaatagcat tcggaacagg aatcaacttg agtacagtaa aaaaacttaa aagtggagag
    15781 agagctgaag aaaaattaaa tcttgccgat gctattaaaa tcacagaatt tggcatgaaa
    15841 aatatgccaa ccaaaatcga aatatggaaa tagtagtttt tctgatctat cagctgtttt
    15901 gccaaagcac ataggaatct cacctccccc cagtaatggc gggccgattt ggttacggaa
    15961 gtatcattat cgtagtcgcg attctcatat taaaatttgt cgcttaaaag ctaaccttgt
    16021 catggcgtaa ctagagaatc aaaatctaca tgtactgata gatttgctat tcatttgtca
    16081 aagagcgcta ggctattttc agcctatgga aatcctttat tttgacccga taaaaaactt
    16141 ccatagaatg aaaaggaaag ggaaaaaata ctttaacgag ttgtatcaaa ttcaagtatc
    16201 ttctcaatca attttgtttc cagttgtcta cgcatatatt catctacata cataaccatt
    16261 cctttttctt cttcataaac tggtttcatg gctaaccgtg aaatataatt ttgatatttt
    16321 gacagaacga tggacatggc aattgaatca ccagaagctg cggctttgat tgtcgttagt
    16381 ggtatgaatg gtatatatcg tttattttgc ttcatatttg acacccaaat actttcctag
    16441 ctcttccaaa gccatttgtc gttggtacca aacactgccg agacttttcc caataatatc
    16501 gccaatttca cgatcattaa gaccgatgag gaaggacata aaaatgattt cttgtctttg
    16561 actaggtaat gctgcaatcg catttgccaa ctcctcattg gaaataaaga ttttcatacc
    16621 aaggacaata aaagtaccac tactattcaa atttggttcc aaataataga actctgtacc
    16681 taaccctttt tgttccaata tttccattga tatttgccgt tggcgaaatc tagcgtactt
    16741 cttttgaata tttaacgcct cattgcagac tactttctta caaaaactgt caaacgtatg
    16801 ttgaatgtgg gtttcctctg agtcgcccat aatattctcc ccctcaaaaa attcattcaa
    16861 ctcgttttac ttctatccct ttccattatt actacaatct agga
//
LOCUS       DAFEML010000050        16875 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFEML010000050
VERSION     DAFEML010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.051"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(386..3091)
                     /locus_tag="LP468_001969"
     CDS             complement(386..3091)
                     /locus_tag="LP468_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL2081483.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(3397..4344)
                     /locus_tag="LP468_001970"
     CDS             complement(3397..4344)
                     /locus_tag="LP468_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL2081484.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            4534..4803
                     /gene="rpsN"
                     /locus_tag="LP468_001971"
     CDS             4534..4803
                     /gene="rpsN"
                     /locus_tag="LP468_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2081485.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(4979..5341)
                     /locus_tag="LP468_001972"
     CDS             complement(4979..5341)
                     /locus_tag="LP468_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2081486.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(5352..6473)
                     /locus_tag="LP468_001973"
     CDS             complement(5352..6473)
                     /locus_tag="LP468_001973"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL2081487.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(6489..6839)
                     /locus_tag="LP468_001974"
     CDS             complement(6489..6839)
                     /locus_tag="LP468_001974"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL2081488.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(6969..8480)
                     /locus_tag="LP468_001975"
     CDS             complement(6969..8480)
                     /locus_tag="LP468_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2081489.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(8802..10154)
                     /locus_tag="LP468_001976"
     CDS             complement(8802..10154)
                     /locus_tag="LP468_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL2081490.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(10307..11383)
                     /locus_tag="LP468_001977"
     CDS             complement(10307..11383)
                     /locus_tag="LP468_001977"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL2081491.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGQNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            11579..13324
                     /locus_tag="LP468_001978"
     CDS             11579..13324
                     /locus_tag="LP468_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL2081492.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(13604..14041)
                     /locus_tag="LP468_001979"
     CDS             complement(13604..14041)
                     /locus_tag="LP468_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL2081493.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(14025..15398)
                     /locus_tag="LP468_001980"
     CDS             complement(14025..15398)
                     /locus_tag="LP468_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081494.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(15720..16208)
                     /locus_tag="LP468_001981"
     CDS             complement(15720..16208)
                     /locus_tag="LP468_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081495.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(16230..16832)
                     /locus_tag="LP468_001982"
     CDS             complement(16230..16832)
                     /locus_tag="LP468_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2081496.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         4746 a         3608 c         3068 g         5453 t
ORIGIN      
        1 aataaaagga tagaacttga cttagaaaat caagttctat cctttttgat atcttaactt
       61 ttggaagaga gatgtaaggc tgctttctac ccatcattct tactactcga agcatagcgc
      121 agttgtcaca acctcttgat aaacggtgtt taaaagcttg catctgcggt aataagctca
      181 accaaattaa aaacataaga agctgttttt atttggtcgt tcttattact tgatgcagag
      241 cagctttttt acaacctctt ggtacacggt gttcaatcag ctgaccctcg gtattagctc
      301 aaaaaaacgg caaaatatga ggaactattt ttccattttt ttctctaata ctcaggtcaa
      361 aacactgatt tcacaacctc tttttttaat gaaaaatatg gctctcatgc gccgcttctt
      421 tgaatttcgt cattttttct tcgatgaacg gatagattgc cgttcctacg attccaaaga
      481 caacaaacaa accgatcatg atccagattg ctttcgtagc atttggccaa taaattcctc
      541 ctgcagattc ccgtaacaag tttaccgcat gagtaaatgg caagaacgga ttgatcattt
      601 ggaagaattt ccctgagact tggatcggat agttcccgcc tccgccagag atcgacagta
      661 ctaagatgat aatagcgatc cctttaccga cattatcgaa taatgcagcc aagacataga
      721 cgatcatcat gaacgctaag gcgatcaaga cagcaaatga cacgctgtag accggatttt
      781 ggacatctac tcctagtaag aaaatattcc ctaatgtaac gatcaagctt tgcgcaatcg
      841 ccattgtcaa aaatgtcagc atacgagcaa cgaattgttc tcgtttcgta aaattgtttc
      901 ggtctttctt tcctaaatag tattctgtcg tagcaacact tgaaagaaga acagcgccga
      961 cccacagaca tagtgcagta taaaacgggg tgctagctga accgttattt gcgattggat
     1021 aaagcgcatt ggtttgtagc tcaacaggtt gtgtaaagaa gtcactttct tttgttgcgt
     1081 ctagtttcaa taatttgatg acttcgccta gatcgacttc ttgttcgcct tttcggatcg
     1141 cgtctgctgc tttttggata ccagctttga tatttggcca gtcattgttg atcaagtccg
     1201 cagcagcgtt cacagctgtt tcgacttctg gcattttttc atttactgtt gtcaatgtac
     1261 cggtgatttc attttttagt gctggccaat cattttggat aaaatcagcg gccaatccta
     1321 atttttgctg aatgatcggt aattcattgt tgtataggtc tgccccttca ttgatgccat
     1381 tgacgatggt atccatattt ccattcagca ttgtattggc atcatggatt tcttgtccaa
     1441 ttgcaggcat ttctttttga tatttttcta aaattgccac tgcattcgtt acagttgctt
     1501 tcgttgagct gagaagcgaa tcaaagtcga tctggtccgc tttgctcagt gcgccttgtg
     1561 cagtcccaat cgtatcgatg acttggtcta gtagagaagt gacagtggaa ctgatttgac
     1621 ctgtattgat accagcaatg atgccattga tattattaac aacggcatca atttgatcta
     1681 gcaattcatc aatagccttc gtgtcttcat tttgaacagc tgtgttcaaa gcagataggc
     1741 ggttttgcag attgcttagc aagggtttta attgatttag ctgatcaata attggctgta
     1801 atttcgtatt tccagcactt gtttgcaatt tagtcaggaa ctcgaccagt ttatcgattg
     1861 cattttgttg ttgagatatt ccgtcaataa agccgttcaa tacattgctg atgtttttct
     1921 tttcatcatc agtcagctta ccatcttcaa tagctgttct tacagtatct attaacgaac
     1981 ctgtcgttgt tgccacttgt ccaattgact tcaatgtaac atctacactg tttgtgatgc
     2041 ttggtatcgc atctttcagc tgagaggcac ctgattttgt ttggtttgct agatcacttg
     2101 cctgattttc taaatttttc acatctggca agatatcttg tacttgttgg atgatcgtca
     2161 agccttgttt tgcttcatcg attccttggt tcattgtctc ttggatcgaa gcaaaatcgc
     2221 cgtcgatctc tgctagttgc ttaccggcat tttggatctc tgggattttt tcttgcaaat
     2281 caaggatgat ttttgcttga tctttcaact caggcatttt gtcattcaat gcaacgactt
     2341 tttcacccat ctcatctact ttagggatgt aatccacgaa ttcatttgct ttattcagtt
     2401 tttccttgat ttcaggtagt tgactttgta attcgaggac ttgttttgtg tagccgtcga
     2461 tcgtgtccaa attttcatct gttgataaaa tcatatcttt aactttattg atacttacta
     2521 ggttcgtatc gatgtcgtaa cctatctcat tgaatacttt caataaagtc gaactggctg
     2581 ttttgataaa ttcatttgtg atttgcgatt ggatcgaact tgctccttta tcggtgattt
     2641 tcggtgcaat cgcattgatt ttttcattta ccgtatattc gatttttggt ttcttgatat
     2701 caccactagt aaaactcagc agatcttctg agaaatcctt tggcaagtaa atacctgcgt
     2761 aatactttcc ggaacggact ccgtcttcta attgttcttt tgaatcaacg aattgccatc
     2821 ctaattgttt atttttatga agcgattcga tgacttgctc cccaatggcc acttctttac
     2881 cttgaaactc tgctggcttg tctgcactgt aaacagcaat tggcagctct ccagtatttc
     2941 catatggatc ccataatgct ttgatgttaa accacgcata tagcgaaggg atgatcatga
     3001 tcgcgatgat cagaagtgtt gcaatcgggt ttttgaaaat ccgtttccag tcaagcaaat
     3061 ataatcgaag cgtatttttg attgactgca tagttctccc ccttcttctt ttttcagctg
     3121 aattacttta ccatgtattt catacttttt tcaatcggct tttttcaaaa aagtcgaatt
     3181 tttggacata tcacggcaat tgtctcattg taatctctta catattgaga aataattaag
     3241 gattacagcc tttactttat catgaaataa aagggaaaga taattttatg ccaaagtttt
     3301 tatctattat acgtatacgc aaaaaagcta aaacattttt tgtctttgcc cctacaaaaa
     3361 tgtttcagct tttttcgttt tttattcctg tatttcttat ttttcgaatg acaggatgat
     3421 tttcccagca ggaggatgtc cttcaactag ctgatgtgct tggatgacat gcttaagtga
     3481 agcagacaga ttcattgaaa taaaaacatg aaaggctcct ttttggtagg ctttgattat
     3541 gccagcaaag gcttctgcat ctagatattc ctttcttgga acaaacgatt cataaaagcc
     3601 ttcctttttt tgccgcaaat ctagatctgg gaggtcattt aatgcaacat acctgccgcc
     3661 tggtttcatg atctggatgc cggtttctcc tttgatactt cctttcgtcg catcgattac
     3721 aaggtctgcc tgatcagcaa attgcagacc tggatttgtt ttatcataag cagcaaatgc
     3781 tgaagctcct aattttttta ccttttcctc atttttactg gatgcactgg ttaagattcg
     3841 gattcccttt tcatggagaa gctggatcag acttgacccg accgcacctg atgctcctag
     3901 tatcattaca gtatctgtcg gctggatttc cgtcaaatgg ttgattagat tataagccgt
     3961 aattcctggc gtgaccattc cggctgcttc ttcccaactc attttatctg gaatttttgc
     4021 tacttttgct gatggcaaca cgacttcttc tccgtaagtc ccgccgactg catggacagc
     4081 tactcgatca cctacatgaa cagttgtgac atctgaacca atctctgtca caataccagc
     4141 gccatcatta cctggtacat aagggaattt caatgttcgt atctctttca tttctcctaa
     4201 acgcaaggca acatcataag gattcacact gaatgctttt atttctacac gaacatgtcc
     4261 agaaccgact tctctgggat gagcatcgat ttcttcaaaa acatcttgtg cttctccgta
     4321 accgttaatt gcaaatcttc gcatggtcac catctccctt tttctttaag tttacgttta
     4381 tgtctttatt ttgacaaaaa aaatgtcttt tcgttttggc gcatgattca aaacaaaata
     4441 gttgtctttt ttcgcgtaac gtgttaaatt atttatctaa aagcgtaaag attacgattt
     4501 acgctaataa aaaataattg gaggaatttg ttgatggcta aaaaatcaaa gattgccaaa
     4561 gcaaaaaaac agcaagaaac gattgaacgc tatgctgctt tacgccagga attaaaagcg
     4621 caaaaagatt acgaaggctt gcgtaaactt cctttagatg ctcgtccaga acgattgaaa
     4681 aatcgtgatt taatcgatgg acgccctcgc ggatacatgc gtaaattcgg gatgtcccgt
     4741 ataaaattcc gtgaattagc acataaaggt ttgattccag gagtaaaaaa agccagctgg
     4801 taatccaagt ctggctgtaa tgtaaaggag gagggcgcat ggaccactcc ttggatcatc
     4861 aaaaaagata cgttcgcttc ttctagcaga aatgctggta ctagaagcag acgtatcttt
     4921 ttttacgcac agctggtcct tttttatatg taaaggctgc atggttactt cgctatattt
     4981 atttagtaac aggagtcagt gcttcgatac ccacactaat tttcaatgct cggtcaactt
     5041 ctgccataat gggtcgatcc aaatggcaga ccttttcttt caatcttgat ttatcgatcg
     5101 ttctgatctg ctccaacagg ataacggagt ctctttctat tcctgttcca gtagctttga
     5161 tcccaatgtg agtcggaagc ttaggtttag ccatttttgc cgttatggcc gcaacaatga
     5221 tcgtcgggct aaaatggtta cctagattat tttgaataac caaaactggg cgtgttccgc
     5281 cttgctccga tcccacgact ggagaaagat cagcaaaata aatatctcct ctttttacca
     5341 taggatcctc cttattcttg atattctctt ggtatccgct gtcctaatcc gcaagccact
     5401 tcatagtgga tcgtacctaa ttgatctgct atatcctgca tagtgatttc tttgtctgca
     5461 tttttgccga taagcgtcac ttttgttccg acaggaaatt cttgaggcaa tcggatcatc
     5521 agttgatcca tacatacacg cccaatcgtt tcacagtagt tcccttctac caatagagaa
     5581 aaaccctgca tctttcgtgg ccagccatct gcataaccga tcggtatcgt tccgatccac
     5641 tctgcttcag gagtgatata tgtttctcca tagccgattc cttcacctgc tgggagtttt
     5701 ttgacttgaa tcaattcaga aaccagctca agtgctggct gcaatggata aacttccggt
     5761 agtgcgtgcc cagagggatt aagtccgtac attgctactc cataacgaat catattgccg
     5821 attgtttcat catgccataa agccgttgca ctattgctga catgtacata tcgaggaagt
     5881 tcgggaagtt ttttcagcac ttctataaag cgttcttttt gcagattcca atatgtatca
     5941 tctgcctgat ctgctgtaga aaaatgggta aataaacctt cccattctaa tacacgactt
     6001 tctttgatga atgcagctgc ctcttttact tcttcaggtg tacaaaatcc gatacgaccc
     6061 atcccagtgt ctgcttttag atgaatcgaa agaggcgtct ctagcttact tttctctaaa
     6121 acagcagctg ctgcttgcaa ccattcccgt gtacctgcag ttactgataa atcatgagca
     6181 acagctacag tcagtgcgtc gtaaggaacc atattcaaga taaggatggg ctgagtaaat
     6241 ccagcttctc tcaactcgac tccttcatct aaatttgaaa cacaaaagcc cgaagctcca
     6301 cctgcaactg ctgcctcagc tgtttcaata gctccatgac cgtatccgtt cgcttttact
     6361 actgcaaaca attcttttcc ttgcggaagt cttgcaactt catttgctac attttcagtt
     6421 atagcttttt tatgtatcac tgctttcgtt gggcggtgcc aagcgacaac catcgttttt
     6481 ccttctttct agtcttccaa aataatttgt gcaaaagctg tttcatttgt atgagtaata
     6541 ctgacccata cattgccttc atgaggtgaa cgcgtcacaa caggctgacc attttcattt
     6601 tttaaaatct cgacatcttg aaaggtaact tttccgatcc cagttcccca agctttagag
     6661 aaagcctctt tgcaagcgta acgcccgcct aaaaattcta cttggcgatg aaaaggcaag
     6721 gactggaata gtttcatttc atcagaggtc aagattcgtg caatgaattt tggtttttct
     6781 tcgatcagcc gagtgatcct aggaagttcg actgcatcga tcccaattcc ttttatcata
     6841 tgcttttctc ttttcaataa atttagaaca ctctcattct accaaattat aaccattttg
     6901 ccacaaataa gtccacaaat aacaaaaatg aaagtttctc ttaaaaaaga gaaactttca
     6961 ttttatgttt aatcgttatt tgaacggatt acaaatccgc gttttttatc attgtgacgt
     7021 ttaccgccat ctttttggct gttattattt ttgctataac cgccttttga tttgtttcca
     7081 cgataattac cgccgtcacg acgattacgg ttgtttccgc caccacgttt gccattttta
     7141 ttgtatcctt ttttctgcat tggcaatggg cgttctggtg tgatcttcac tggcactgca
     7201 tcagctggat cttttgctgt cgtttttagc aaaagtgcaa ctaaatcttg tgcagaatat
     7261 tcttctaata atttatctgc tgtttgcagg tatttatcta gaccattttc tgcaagtttt
     7321 gtttcgattt gttcaactgc agcacctaat tgacctttga atgcttcttt ttcggttggt
     7381 ggacgtaaag tcgtcatccg ttttttcgtc aagttttcaa tcacatgcaa gtagtccatt
     7441 tcatttggtg taacgaaagt cacagacata ccgccttttc cggcacggcc tgtacgtccg
     7501 atacggtgaa cgtagctttc tggatcttga gggatatcat agttgtacac atgagtgaca
     7561 cctgaaatat ctaatccacg tgcagcaacg tctgtcgcta caaggatatc taaatgaccg
     7621 ctcttaaatg aacgcaatac gctcattcgt ttttgttgag acaaatcgcc atggattcct
     7681 tctgcacggt aaccgcgtgc ttctaatccg cgtgccaatt cgtctacacg gcgttttgta
     7741 cgtccgaaga cgattgttaa ttcaggtgtt tgaacatcaa acaagcgagt catgatatcg
     7801 aatttttcgt attcttttgc gcggacatag tattgatcga tcaagtcagc tgtcatttct
     7861 ttcgctttga tcttcacatg atgtggattt ttcatgaatt taacgccaat attcttgata
     7921 gctggcggca tcgttgctga gaaaagtaat gtttgtcttt gatcaggaac ttgtgaaatg
     7981 attttttcga tatcttccaa gaagcccata ttcaacattt catctgcttc atccaaaact
     8041 aatgtttgaa cggttccaag tttcaatgtg tggcggttaa tgtggtcaag catacgtcct
     8101 ggtgtaccca caacgatatg tggacgatct ttcaagccac ggatctgacg gccaatatct
     8161 gctccgccgt aaacggcttg tacacgtact tttttgtcgc gccctaaacg atataattct
     8221 tcttgtgttt ggatagctaa ttcacgtgtt ggtgcgataa ctaaaccttg taattcgtga
     8281 cgatctggat cgattttttc taacattggt aatccaaatg cagctgtttt ccctgtacct
     8341 gtctgtgctt gtccaataac gtcttttcca gctaatgcta gtggaatcgt ttctgcttgg
     8401 ataggcgttg cttcttcaaa accagcgcgt tcgactgatt tcaacaattc tggtgataat
     8461 tctagttctt taaatttcaa atgaatcctc ctatatggtt gttaactgag gatgtagctt
     8521 ttttgctacc ccgtcgattt gttcggtcaa agtgtattgt ttctttttga cagtggccac
     8581 gcacgttttt atccattctt agcccctgtg gcaccaccga aaaatcactt tgcgaagttt
     8641 aggcattaga aaagccaaac gggtcgcgtt cagctttatc attattatga catctggctt
     8701 caacaagttg tttctatggc aaaaccagtc caatttctct tcatctttcg gcaataggtt
     8761 attctaacat agtttttcgt tttctgcaag tttacagatt tttatttcat ttgctgaagt
     8821 tgttctacca cttcaaataa gcccatgctg ttgctgcctt ttagcataat actatctgtt
     8881 gctgcaagat tttgtttgat agcatcaatc aatttattct tttctttttc aaaatagaac
     8941 acaggtagtt gggggtattt ttggttcaat tcttctttta gtgcatgcat ttgttcccca
     9001 taaaggaaaa tcatggcgaa tttctcagga tcgatatgtt cactcatttg cgcatgcata
     9061 tttaaagact ctttccctaa ttccagcata tctgctaaca cagcgattct gcgtcctttt
     9121 gttggcagat ttttaaaagt atctaatacc agtcccatgg ctgttggatt tgcattgtag
     9181 acatcgctca aaatagctgc accatttcct gccgttagcc attcggttct gttttgagtg
     9241 atagaaacat gggcgagccc ttggcgtatc tcaggtatgg acagtccaaa gaagcgcccg
     9301 atcgtatacg caatcaaagc attcgttaca ttataacttc caggcagcgg gatcgtaaat
     9361 gtttctcctt ctactacaaa atcggtttgt gcttttcctt ttgctgtcac ttccgcatga
     9421 acatcgccat ttccaatacc gaatgttgtg actgtttgta ctaatgttgc cgttaaaggt
     9481 gtcagcaacg gttcatctgc gggcacaacg agtaatccgt ctgatacaag tccgtcagtg
     9541 atttccattt tggctttagc gattccttct cgcgacccaa gattttctat gtgtgcttca
     9601 ccgatcattg tgattgctgc agcttttggt tgagccataa gtgaaagttc cgtgatttca
     9661 ttggcgtgat ccatgcccat ttccaaaacg atcttttctg tatcttgggg catgtgcaaa
     9721 atcgtgtaag gaagaccaat attattgttg taatttcctt gcgtcttata tgttttgtat
     9781 ttttcagaca agacagacgc ggttagatct ttcgtggtgg ttttaccatt gcttcctgta
     9841 attgcaacga cttctgcgcc tactttttcc aagtaatagg ttgccaattg ctgcatggct
     9901 ttcaaaggat ctgctacagg aataactgga aaattttttg gagcttgttc aacaggcaag
     9961 ctccaaaatg aagcagatgc tccgtttgtg atcgcttgct ggataaattc atgtccatct
    10021 cgcgtaccag caagaggaac gaataaactt ccttcggtta tcttccggct gtcaaattcg
    10081 acattggtaa tctttgtcag tgcagagcat tcgctgccca cggcttgtgc aatttcttgt
    10141 attgttagat tcattgagat ctctcctaaa aaaggttgtg aaaaaagcgt ttggcctaaa
    10201 cggcgggttc gcatgactct cacttccaag taaatttctc tattcgtatt tagaagctag
    10261 aatgaacgcg gttacgcaat cactccagcc tcttctttat ttctctttat tcattttttt
    10321 caaaaaaaga ttgacgctga tggtatcgat tcattcctaa ctggatcagt tcttcaatca
    10381 aatcaccgta tttcaagccc atattttccc ataagagtgg gtacatactg aactccgtaa
    10441 atcctggcat agagtttaat tcattcagga ataattcatt tttatttgtc aaaaagaaat
    10501 cgcaccggct caatccgctt ccacctaaca tcgtgtaagc taacttcgcg tactcttgcg
    10561 ctttttgata aacttcttct ggcacttcgg ctggaatctg catttcgatt ttattattga
    10621 tatattttgc ttcataatca tagaatgcta cgtcttttac gacttcacca ggcaaagtcg
    10681 tccgaacgtc ttcatttcct aatacagcaa cttcgatttc gcgcgcttca attccttgtt
    10741 caacgattgc tcgagaatca tactgatagg ctgttgctaa agcattttgc agctcttctc
    10801 ggttttctgc ttttgtaatg ccgacactag aacccatatt cgccggtttg acaaacatcg
    10861 gataaagcaa agaaccttca cattgatcaa atactttttt aggattttct ttccattgat
    10921 tcttaagtac tggtacataa ggaacttgcg gcacaccagc agcttgtaaa atatacttgg
    10981 tcatgatttt atccatggca catgcactgg tcaatacgcc tgcgccgaca taaggcatat
    11041 tcaatgtctc taagaagcct tggatcgttc catcttcacc gttttgccca tgtaaaactg
    11101 gaaaaacgat ggctccttct tctttgattt cgcccggatt gatcactttt cctgtaaagc
    11161 cttcctctgt ctgtccactt gggtcccatg aaagatgcaa gacatctttg ctggcaggtt
    11221 tttctgttag taatggacct ttgacccatt gtccttcttt tgtaataaat acgagttgaa
    11281 cttggtaata attataataa atggcattta aaactgaaaa tgcggaaaga atggacactt
    11341 catgctctgc gctgcgtccg ccatatagta aagtaatctt caaaagattg tcctcctgta
    11401 ttctaaatcg ttcagtgatt tactctcata ttttagcaca aaacaaaaat aaacgaataa
    11461 cttatttata aaaaaacgag ccagcttcta aaagaacgag cgtcatttat tttttgtcag
    11521 ctagattatt tgtcccgttt tttataaaaa gttatgataa agaaaaggag ggatgatgat
    11581 ggcgcaaaca aatccacgca gccgcttggc agaaatcatt cgagtgttca tcaattacaa
    11641 tgtagtgcca aactttgtac agcaaaaaaa tcccgaacag gtaaaaaaag cctttgaaga
    11701 actaggcccc accttcatca agataggaca gatgctttct gttcgagaag atttgctttc
    11761 ttctgccttc actcaaacat tcaaaacatt acaagatagt gtacctagcg acacattttc
    11821 aacggtcaaa aagacgatcg aaacagaact ttctctttca ttatcagata tattcgatga
    11881 tttttcaaaa tcgccttttg cctctgcttc tatggggcag gctcatcgtg ccaagctgaa
    11941 gaacggtgac gcggtagtcg ttaagatcca acaccctaac atcgccgaag agatccgact
    12001 tgatcttcaa ctatttgaac gagcgatccc tttgatcaaa tacattcctg aaactagcgt
    12061 agttgatcta aaaggggtac tccaagaagt aaaacgttcc ttgatcaatg aaatggactt
    12121 cttaaaagaa agtcaaaatg gcgaacaatt ctatcaaaag aacaatggct ggaaagagat
    12181 ccgcagcccc aagatttatg acgctttttg ttcgaaaaaa gtgatcgtga tggaagaaat
    12241 gtctggtaaa aacttgaatc atttaatgaa cgccgaaaac aaaactgaaa cttttatcac
    12301 tggaattcaa aacaagcagc tgaaacaaga agttgcaaag cttttagttg agaactttat
    12361 gaaacaggtg tttgatgatg gttttttcca tgctgatcct catccaggga atctgctatt
    12421 ccatgtacta acaaaagaag aacagacaca agctagccga aaaactgaaa cagtccatga
    12481 aaaagagttc ggttcctttg cttttcgagc ctccacttct gcagaagacc ctgttgcgcc
    12541 atataccatc aactacatcg attttggtat gatggggcat ctttctgcag gacttaggca
    12601 aaaactcaca caagccgttt tagcgctgta tacgaaagat gcttatcgaa tcgaaaaagc
    12661 ggtccttcga ctttgtcagc aagaaggctc gtttgatgaa agtcggttcc accaagaact
    12721 gacaagtttt cttgaacagt attatgattc tcctattgat gaaatcaact tgcaagaagt
    12781 attcacacat gtcgtgacga tttgtcatca aaataatctg cagttcgatc gtgatatcac
    12841 gcttttgctg aaagcatttg ggacattaga aggggtgatc cgcgtcctcg atcctgaagt
    12901 ttccctcatg gaagtcgctt cgccttttgc tcaacattat tttctcactc atctggatgt
    12961 agaagataca ttgaaacaaa gcggattaga cttattggaa gggatgaagg ctgcgcctaa
    13021 gatccctcaa cagctccacc atctattaga aatgtggact tcgggacaag gaaaagtcaa
    13081 tttggaattg aaaaagcaag acaaattatt gagcaggatc gaaagtatga tcaatcggct
    13141 tgttttcggt atgattttag ctgcattgat cgtagggtcc tccctgcttg tccaagcagc
    13201 acctgtagaa aacgcagagg tcgtttcctt attagggata tttacgtatg ctattgccgc
    13261 attcgtcatt atttttttgg caatcgatgc attgatccaa atgtataaga agaggaaaaa
    13321 gtagaaaaag gttgtgacag aaagaatcag cttcaagaaa taagaagggg ttttacataa
    13381 attgtttctc aaatttttgt gaaaattcgg cttatttttc gaagaggcta cttctgaaac
    13441 accgagaata aaaaatgtga aaaagctgtt ctgcacccag taataagaac aatcaaaaag
    13501 ggaacatgga acacatttat cctgtttccc tgttcccttt ttgatgtatt cgagcataaa
    13561 taaaatacct tcgttaccta ctatcttctg tacttggtaa accttagtca attgcctttt
    13621 ttaacgcttg acgaaaagac atatgatctt tctccgtaaa gggttttgga ccctttgtcc
    13681 ttatgccagc ttttcttaac tttccactat gataacgttg ttctagaagc gtgccgatat
    13741 tcgcttcgtc aaattctttt ccagagtgat ggaacactcg cacacccttc ggcaatacaa
    13801 gtgaagctaa accataatct tgcgtgatca aaaagtcatt cttcttaacc ataccgacga
    13861 ttttataatc cgcactatca gctccgcggt ctacgtagac gatttggaca tgattagcgt
    13921 attctttggt cgtataatgg tccacactgg tcacgataac cacgtcaaga ccataggatt
    13981 ctcctaattt tatgacatct tcttttactg gagaaccatc tccatcaatg aatagcctca
    14041 ttctttttcg ccttcttcca taaatgataa acagttacta atccgctcag taaaagacca
    14101 acattgatcc attttgccaa gataagcagt tgtacacttt ctatcggcac tgattcatgg
    14161 ttcagcgtga tcaataatag atggattggc tctcccattt cttttgctaa aacaaacaaa
    14221 agcgtcatca ataaaaactg gtggatcaca ctccctttat tttgagtagt atacttgaca
    14281 acgatccggc gatccattgg aatagctgta tcagtttgat aatattcctt atttagccag
    14341 ctgcctgtta ctacgtgcca gaaactaagc agaaagacac ctatcgcaaa accatttgga
    14401 atcaagagga ccaataaaga agaactcagt ccaagcaatt gcatagccaa tggagaccat
    14461 gttaaacgtt tcaaaatcca tggtccgact atttttgctg caatcaagcc tgctgcataa
    14521 ggcaaataca taaaaatcga aagtttttct aatccgtaca gtatgccaac ataaaaactg
    14581 ctaaataaaa aaaggaaatt ccctagcatt ccatttagaa aagtaaacag atttagccag
    14641 cttggcaact tccattcctt cttctggtgt cctaaaacaa acacgaacaa gatgaacagc
    14701 agcaagaaac cataaatagc aagatcaaaa agcctttcat cgaataacaa tcgggcattt
    14761 ctcaaaagaa acaataagcc aaagaatatc aaaaataaaa caagctctcg cgtagctacc
    14821 agatttcttt tgatgtcttt gaaatccagt tcgtaacgcg gataatgact aaccgtatgg
    14881 taggccatga cgtaaaaaag tgtataaata gtaaagcttg ctgcaatctg agtcggtgca
    14941 ggcaactcaa tcgcttgata caggagaaat agccagatag ctgcaaataa gtactttttc
    15001 ccatccatat tgataaaacc ttgcgtcttt tcgtgaaaat tgaccgtggt attagcaggt
    15061 acaagccatg ctgcactcag ccctagcaaa acacttgaaa aataaaataa aggaaaataa
    15121 aatacgccta atattccaag caatgaacca gcaccaccaa tcagcagagc gatcatcagc
    15181 aacgtgtaac tatctagacc aaatcgtaga ctgttgacta aaaatagtcc agtcatccga
    15241 aaggcataaa acagcgtaaa tggcaaaatc gtcagccaat tatgcgagtc tgttagtccc
    15301 aaaaataaaa gataaggaat aaaaataacc gtgttactta agataaaggg cgttgtttgt
    15361 gtaaaattac gcccaaatcg tttgagtttt tcgaacatga caatggctcc ttaaacagtc
    15421 ttataactaa tctgctcttc gattttagca ttaaagggga aataaaccaa ttttacagaa
    15481 tatattcttg taaaaaaaaa tacagaaaga agcataagct tctttctgca tttttacggt
    15541 acttgattac tcaagcagac aagcccttct ccacaaaagt cttgcccgac acccctgcat
    15601 ccggcaggtg ataaagatag aaatcaatta tcctgtgcct ccaaaatcaa ttaggagctc
    15661 tgtaaaccag agtccttctc gacccgtcgc ataaatttac tttaacacag ttcctatgtt
    15721 tatgcgagag cttttttcat tttataatcg accatttgaa atccttgacc gatatctgaa
    15781 ataagttctt ctgtaatctc aaatccttca tgcttataaa cctcgattgc ttgatgattc
    15841 ccctgattca ctcgcaaaaa gatctctctt tcctttgttt gcgcagcaag ttcttcatac
    15901 cagcgaaaaa ctgaagaagt caatccttga ccacgtactt tatttagcaa atataattta
    15961 cttaaataaa tttttccatt tatctcttca taagcagtgt aaccgacagt cttttcttcg
    16021 ctttttaata aaaagtagga cacaccttct gtcagttctt tttgaatctg tttttttgac
    16081 tgataagttt tcagcatgta atccacttgt ttttgaccaa tgatcggcac aaaaacttcc
    16141 ggccatactt cttgtatgac tgccatcagc tcatccagtt cattttctgt tacttttatt
    16201 ttttccatac acccacgtcc ttttttacat tataaatgac cttgcgcttg atggaataaa
    16261 aagagcatga tcatgctata cacacccacc gaccacggtt tcaagaaaat cacaatctgc
    16321 ataaattccc taaaagataa tttcgtcaaa ccagctacta gacagatcaa gtcgtctggc
    16381 gcaaagggaa gcagcaaggt aacaactagt acttttttaa tatctttcgt ttttcttgtc
    16441 agcaattcat caaatttctg atactttttt ggcgataaaa taagctggac aaaggctacg
    16501 ccatagtaac ggacaagcaa aaatccgatt gcttccccaa tcactaggcc aatacaacta
    16561 tataaaagcc caaatccatt gccaaacatc agcatgcccg ctactgagga gatccctccc
    16621 ggcaaaatag gaatgatcac ttggatcact tgcaacagaa caaatatcat cactgcatac
    16681 ttgccaaatt gctggataaa cgcttgcaaa gacgtgctcg atcgaaaaat cccatgatga
    16741 taagcataaa gaatcaacac aaagaaaaaa aacagaccaa taatgggcat gatctgaaga
    16801 catttttgta aaactgatcc ttttttagac atctatattc cccacatctt ttttcattta
    16861 ttaaaactgc ctcct
//
LOCUS       DAFEML010000051        16654 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFEML010000051
VERSION     DAFEML010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.052"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(312..611)
                     /locus_tag="LP468_001983"
     CDS             complement(312..611)
                     /locus_tag="LP468_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081497.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWGSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(617..847)
                     /locus_tag="LP468_001984"
     CDS             complement(617..847)
                     /locus_tag="LP468_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081498.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1097..1297)
                     /locus_tag="LP468_001985"
     CDS             complement(1097..1297)
                     /locus_tag="LP468_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2081499.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(1602..2834)
                     /locus_tag="LP468_001986"
     CDS             complement(1602..2834)
                     /locus_tag="LP468_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL2081500.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            3089..3658
                     /locus_tag="LP468_001987"
     CDS             3089..3658
                     /locus_tag="LP468_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2081501.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(3836..4276)
                     /locus_tag="LP468_001988"
     CDS             complement(3836..4276)
                     /locus_tag="LP468_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL2081502.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            4434..5198
                     /gene="map"
                     /locus_tag="LP468_001989"
     CDS             4434..5198
                     /gene="map"
                     /locus_tag="LP468_001989"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL2081503.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            5230..6153
                     /locus_tag="LP468_001990"
     CDS             5230..6153
                     /locus_tag="LP468_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL2081504.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            6229..7368
                     /locus_tag="LP468_001991"
     CDS             6229..7368
                     /locus_tag="LP468_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL2081505.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            7361..8161
                     /locus_tag="LP468_001992"
     CDS             7361..8161
                     /locus_tag="LP468_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2081506.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            8161..8988
                     /locus_tag="LP468_001993"
     CDS             8161..8988
                     /locus_tag="LP468_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2081507.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8966..9700
                     /locus_tag="LP468_001994"
     CDS             8966..9700
                     /locus_tag="LP468_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2081508.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            9800..10666
                     /gene="rfbA"
                     /locus_tag="LP468_001995"
     CDS             9800..10666
                     /gene="rfbA"
                     /locus_tag="LP468_001995"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL2081509.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            10680..11252
                     /gene="rfbC"
                     /locus_tag="LP468_001996"
     CDS             10680..11252
                     /gene="rfbC"
                     /locus_tag="LP468_001996"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL2081510.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            11274..12302
                     /gene="rfbB"
                     /locus_tag="LP468_001997"
     CDS             11274..12302
                     /gene="rfbB"
                     /locus_tag="LP468_001997"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL2081511.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            12400..13251
                     /gene="rfbD"
                     /locus_tag="LP468_001998"
     CDS             12400..13251
                     /gene="rfbD"
                     /locus_tag="LP468_001998"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL2081512.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            13285..15318
                     /locus_tag="LP468_001999"
     CDS             13285..15318
                     /locus_tag="LP468_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081513.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            15362..16642
                     /locus_tag="LP468_002000"
     CDS             15362..16642
                     /locus_tag="LP468_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL2081514.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         5149 a         2865 c         3388 g         5252 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgttcccc aaaaaccact gccccataag
       61 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
      121 aaaaaagtga gaaaaaaggc ttataattgg agtggtagtt aattagtgac ttatttttga
      181 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
      241 cttaaaaaat atctcctttc ataagtatgg tgataaaatc cgttccgggc taccttttta
      301 ggtagcctac tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      361 taacgccgat gatcgcttcg agcgtctagc acatcagtca cgatatcaaa caaaaaatat
      421 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      481 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga accccacacc
      541 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      601 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      661 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      721 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttgtcttttt
      781 cgttgctttg ctcataaaaa tctgcatatt catcactaat attttttcta ataaattctt
      841 ccatcataaa gatcacctcg aaaagagtat acgaacaaac gttctttttg taaaggtgga
      901 atttattata ctaaataaat aggtgaacaa gtacttgtgc caaattatgt gccaaaaaaa
      961 atcgaattta ataaaacaca aacaaaaaga aatcctatta tgataacatt tcttataata
     1021 acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac ccctgtatcc
     1081 tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa ctgctatgtc
     1141 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgcg
     1201 tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg attactaaag
     1261 aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt cgaattaaac
     1321 gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct taactctagc
     1381 ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga ctttttatta
     1441 tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt accatataaa
     1501 aaaacggtgg ggttgtttag cgaaataaag gatctaagcc aatagcttag atcctttatt
     1561 ctatgcttta tattattttt tgcatgtgtg cgaaagtata ctcaagccca atcgccattt
     1621 cggaaaatcg gtactgtaga gccatcttca cggattccgt cgatatccat cttgtcagat
     1681 cctaccatga aatctacgtg ggtttgactt ctattcaatc cagcttctgc taattcttca
     1741 tcggacattt ctgtaccgcc tttcacactg aaggcataag cagaacctag tgctaagtga
     1801 ttcgatgcgt tttcatcaaa taatgtattg aaaaagatga tgccagattg agaaataggt
     1861 gaagggtcag gtacaagtgc gacttctcct aaacgacgcg caccttcatc tgtatcaagc
     1921 agttttgcta agacatcttc tccttgttcg gcagaaaaat caacaacttt tccatcttta
     1981 aaagtaaatt tcatacccga gatgatggtg ccagcataac tcagtggctt tgtacttgaa
     2041 atgtaaccat ctactcgatg actgtcaggt gctgtgaaca cttcttccgt cggcatattt
     2101 gccatgaatt tttctccacg agcattatag cttccagcgc cttcccaaag atggttttta
     2161 ggcaatccga taatgatatc tgtaccggga gcagtatagt gaagggcaga aaattgttct
     2221 cgattcaatt cttctgcttt ttttgctaat ttttcatcat gcttcttcca tgctaagaca
     2281 gggtcttctt catagacacg agtcgttttg aaaatctgat cccataatgc ctcaacttgt
     2341 ttttcttctg gcagttctgg gaagactttt gctgcccatt gtttaccagc cgcagccacg
     2401 acagtccaac tgactttatt tgcttgagtt gccttgcgta aattcattag tgctttgcca
     2461 ttcgctgatt gataagacgc tactcgatgg ctatctacac cagcaaatgc atcgggatcg
     2521 gcagaaacaa cgctgatcct gcttgctcct ttttcaagcc attcatccgc ttgatcgatt
     2581 ttagattgtg gtacattctc aatacgatcc gttgcagcat gtaaaagaaa ttctctttgg
     2641 atctggtcgt cagtccattg aacgataacc tcagcggctc ctagtttata agcttcttgt
     2701 gtgatcaatc gagcaagggg tgcctgttcc acgctgatct gtaaaacaac tgtgtgtcct
     2761 ttttctgtgg ctacgccagt ttctgcaatt aagcgtgcat atttttttag aagttcatta
     2821 aaatcagata acataataaa aattcctcct caccattttt tctggtaact attagcatga
     2881 taccatttaa ttatgattca aacaatgagg ctttaaataa aaaaaggagg ttattttttt
     2941 aaggttaagt ttcatgatat atgttactac ttgctatttc agcttgtgaa gaaaatcaaa
     3001 aactaatttt gcatatcaaa aaaaacatgt tacaatgaaa ttaatcaatg gtggaagcgt
     3061 tataaaaaaa ttaaggagat taaaaaatat ggcaagaaaa aagacgatta ctagagaaca
     3121 gattttggca gctgcttatg aagtagctgc caccgatgga tttacacgat ttactgcgag
     3181 aaacatcgcg aacaaaatga attgttccac gcaaccgatt tatcttgagt ttaaaaatat
     3241 ggatgacttg agacaagctc tttttgagca gatctatgat catttacaat atgaagtgtt
     3301 cactgttgag catacaggga atacgattat cgatcttgct tttaattata tccattttgc
     3361 aagaagagag aagaagttgt atcgttcact gtacttagaa gaatatggtg gaggaaaaga
     3421 gatgcagaat ttctcttata cttactttgt gaatacagtg aaacgcgatc cagcttatgt
     3481 gaatctttca gaagagcaga tcgaatcttt gtataatggg acatggatca tagctactgg
     3541 gatcgcagct ttgatgtctt caagcatcat ccatccaact gatgaacaga ttgaaaagat
     3601 gatccaagac agtatagatg ctatcttgaa attcaaagaa ccaatcgaaa tcgattgaat
     3661 atactcaaaa gttccacaaa tcagtaggta acaagagatg tgtcaaaata aggaaaagtt
     3721 cgtttttctt acagcgtatg catttttaac tcccgaagaa ctcttccatg aatgcaatga
     3781 ataaaagagc catacagatt gaataaatct ggatggctct tttattgcaa gtatattaaa
     3841 tttttgcgac tagttcttta gcgaaagctt ctaaattttc gatatcttct tcttcagcat
     3901 tcagatccac tttaacattt tcggctcctt ttgatgcgcc tgtttttgca aaagcagcat
     3961 cgaaatcatc caccgatttg cagaattcat cgtaaaaagt atcaccagat ccgcagacac
     4021 cgtaaatttt tcccaataga tccaattctt gcaagtcttc ataaaagtct acgatctcat
     4081 caggcagatc gccatcatcg tatgtataag tagctactac gcaaatatct gcctcctcga
     4141 attcatctgc atctacttgg gtacattcgt tgatttcgac ttcgatatcc agattttcaa
     4201 atgcttctgc aacaatatcg gcgatttctt cagtgtttcc tgtcatgcta gcatatacga
     4261 tttttgctaa agccatgatg tgcctcctcg tttataatta tttaacaatt atgaattata
     4321 ccaaaacatc attgaaaaga aaataaaacc tagagacacc tggggaatgt catttggcta
     4381 aatgtatgcc gctatgttaa aatgagaggg atttgtaaaa aggagacgaa aatatgatta
     4441 ctttaaaatc agcacgtgaa attgaaatga tggcagaatc tggagcttta ttagcagatg
     4501 tacataaaaa tctgcgtgat tttataaaac caggaatcac aagttgggat attgaggtat
     4561 ttgtcagaaa ctatatcgag agtcatggcg gaattgctgc gcaaattggc tttgaagggt
     4621 atgaatatgc gacttgtatc agtataaatg atgaaatttg tcatggattc cctcgtaaaa
     4681 agcctttgaa aaacggtgat ttggtaaaag tcgatatgtg tatcgatttg aaaggcggca
     4741 tttctgattc ttgttgggcc tatgtagttg gagaatctac acctgagatc gaccgattga
     4801 tggaagtaac gaagaaagct ttgtacatcg gtattgagca agcacaagta gggaatcgga
     4861 ttggtgacat cggtcatgct atccaaactt atgtagaagg cgaaaatcta gcgatcgttc
     4921 gtgattttat tggtcatggc gttggtccta cgattcatga agaaccagca gttcctcatt
     4981 acggagaagc tggaaaaggg ttgcggttga aagaaggcat ggttatcacg atcgaaccta
     5041 tggttaatac cggaacttgg aaaatgaaaa tggatcctaa cggctggact gcgtatacaa
     5101 gagacggcgg actttcttgc caatatgaac atacattggc tattactaaa gatggtccaa
     5161 gaattttgac atcacaagga gaagaaggca cttattgatc tatccagtca ataggtacgg
     5221 gagaggtaca tgaaagtttg gaacaaaata aaacaaaatg aaaatctgat gcgctttatt
     5281 gagacgactc aaaagcgcat cactgattca gaaatgagta cgacctctgt cgtcgttgct
     5341 tattatttac tcttgtcttt atttccattg attattgctt ttggtaatat tttaccgttt
     5401 ctccacatcg atcaagagac tgtactgacc tatttacgag aagtgattcc tgagaccgtt
     5461 taccagttta tcggtcctgc aatcaaagac cttttgacac aaagttcagg aggcttgtta
     5521 tccgtttctg cattagcggc tttatggtct gcaagtcaaa gtatcaatgc tttgcaaatt
     5581 gcgatgaata aagcgtatgg cgtagaaaat agaaaaaatt ttttgatcgt ccgtttcttc
     5641 tcactaattg tcattgtctt gttcatgatt gctattagtg gggtaactat cgttcttggg
     5701 ttgggacagc tgattttgga tgctattcag ccaatcgtac aaatacccgt gaactttatc
     5761 gatcagttcc aaactttgaa gtggccaatc acattggtag ctttatttgt catcatgttc
     5821 ttgatttatt taattgtccc taatgctcag ttgaagttga agacgatcat tccgggcacg
     5881 atcttcgcta ctgtcggctg gatgctgtta tcacaagtgt ttagtatcta tgctaggtat
     5941 tttgcaacga ggatcagcgg ttatcagatc ataggaagtt ttattgtact catgctttgg
     6001 cttaattttg ctgctacgat catcattttg ggcggaatca tcaatgcagt tgttcaagaa
     6061 tacgtgacgg gtcatcaaat caaaaaacgt cgagatccaa gccgaaaatg gttcaataaa
     6121 ttgaaaacta aattttctca taaaaaaaag tagaaacaag agttcttatt gtaaatttat
     6181 atcagtaatt tataataatt atgactctta attaaagtag gtgcccatat gcttgtttct
     6241 tttagtatgg ttataagatt ttttctgaca attttattat cactgatatt aacacctgta
     6301 ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac caaatgaaag aagaataaat
     6361 aaagttccaa tgccttcagc gggcggactg cctatcttta tttcatttgt tatatcgact
     6421 ttattcttat tccgtaaaat tatccctcaa tcgtatattg taccgatctt gattgcttct
     6481 ttagtaatca tagtcacagg agtgctcgat gataaatatg agctgacacc taaacaaaaa
     6541 agtataggga tcttgattgc ttctcttatt atttattttg tagcagatat acgtattgat
     6601 tccttcacgc ttccttttat tggatatatc caactaggct ggcttagttt tcccgtaacg
     6661 attttttgga tcttcggtat cacgaatgcg gtcaatctga ttgacggttt ggatgggctg
     6721 gcggcaggga tttcattgat cggtttaatt acgataggaa tcattggata ttttttcctc
     6781 catgcttcta cagtgtatat tccagttgtt attttctgtc ttgtagcaag tattatcggt
     6841 ttttttcctt acaattttta tccggcaaag atttatttag gcgatacagg agctctattc
     6901 ctagggttta tgatggccgt cctttcacta caagggctga agaacgtgac ttttgtttca
     6961 tcgatttctt tgctgatcgt catgggagtg ccggtaacag acacgttttt tgctatcatt
     7021 aggagaaaag caaaccgtgt ttctttttct acagcagata aaaaacatct tcatcaccga
     7081 ctaatcagtt taggctttac tcataaaggt gctgtcctga cgatttatgc gatggctttg
     7141 atgttttctt tcacagctat ggtcatgaat tatactggaa gaatcggaac gatcatattg
     7201 attattgcca tgttgtttgc tgcaatttta ttatttgaat tgattggtct gatcaatgag
     7261 aaacatcagt ttattttaaa aacattgcga tttttaggga ataaagagta ccgtacgcaa
     7321 gtaaaacaga aatatttgaa gaaatggaac cgtcatatag atgaataaca aattaaacca
     7381 gccgatcctt attagtattg tgacggcaaa cagtgataaa atttttcgga cactagataa
     7441 ttttatttca actgtaaaag atgaaacagc agtaaaaatc cgaatttttg acaacaattc
     7501 acttcccgag tacaaaaaaa gactaacaga gtataggaaa tatccctaca tcgatatcta
     7561 ttttcatgat gaaaattccg gatttggtta tggacataat cacaatctga tagctagcga
     7621 ttctcgctat ggcattattt gtaacccaga tattttagtg gatgaagaga cagttacagc
     7681 attggtcttg ttattgaaag aacatccgga atgtgcgatg ttagcaccta agattcttaa
     7741 tgaagatgga acaactcagc acctcatccg tgagcagctg gctgtttttg attacgtttt
     7801 gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac aaacgactgg ctgtgtttga
     7861 atgccgagga ttgcctactg atgctaatag ttatgtacgg atgatctcag gtagttttat
     7921 ggtagctgat attgataaat ttaaagagat aaaggggttt gatgagcgtt tcttcatgta
     7981 ctttgaagac aacgacttgt gtttgagttt tgaaaaagca ggttacaagt tattgtacac
     8041 acccttttat gcagttatcc atttttacgg gaagggtgcg catcgaaatg caaaactgtt
     8101 tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag tgggggtggc gttttttctg
     8161 atgaaaccag aaatattagt agtcgttgtg ctttatcagc aactattcag tcaatctcca
     8221 gcttatggac cattaagcaa agcacttagc gaaaagcaaa ttcagcttat tatttacgat
     8281 aatagtcctc aaaggcagca aaatgagctg tttgaaaaag aaaatatcgt ttatcatcat
     8341 gatccgcaaa atcctggttt agcggtggct tataattttg cgttgtctca agcagatgaa
     8401 ggaacacgtt gtctcgtcac tctggatcag gatacgaggc tagtcgacga ttattttgaa
     8461 ctattgcgta aagtaacctt tacagatgaa tgtgttgctg cagttccgat gattttttct
     8521 gggagccgac aagtttctcc cctatattca gatcgttata tcaatcgtac agctcaagca
     8581 gtagaagttg aaggcccaac agctgaacga atcatggcaa tcaattcagg tgttgcctgg
     8641 tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg ctttttcttt agattttttg
     8701 gatcattggc tgttttggaa agtggatcag ttggaaaaaa ctgtggagat ccttcctgta
     8761 cgaatggaac atgatctttc ggttttagac tatgaaaaag tttcaagtaa tcgataccgt
     8821 tctattttac aagcagaaaa tcgattttat catgaatatg atcaaaggca tttatccagt
     8881 caccgacgac aattattgtt aagaacagct aaacagttct tgaccgtcaa aaaccggcat
     8941 atctggcgga tgactttgcg ctcatatgtt aagaattgga aggtgtgaat tcgtgcgttc
     9001 ggtttgtata gctaccttta atggaggcag atatttaaga gagcagttag atagtatttt
     9061 atctcagctt tcagcagaag atgaagtagt catttctgat gatgggtcag tagatgatac
     9121 atgggatata ttaactgaat acgcagaaaa agataagcga atccagcttt tttcggggcc
     9181 tcgtcaagga ttgatcgcta attttggtta tgcgatccag cagacgaaag gagatctaat
     9241 ctttttggca gaccaagatg atgtttggtt ggagacaaaa gtgaaaaaga tcactgacta
     9301 ttttgagcag aatccggatc agctagtagt agtttctgat ttaatcattg tggacagcga
     9361 gctgcaagag atccatgatt cgtatttttc gtttcgaaat tccaaagaag gatggcttaa
     9421 taatgtgata agaagtcact atattggtgc tggtatggct ttccggtctt ctttaaaacc
     9481 cgatattttg ccgatcccgt cagaagtgcc gatgcatgat atgtggattg gtttgctggg
     9541 aggaaagaag actgggttcc taagagaacc gttaactctg taccgaagac atgatttaaa
     9601 cgcgagtgag attgaaacac attctaaatt acggcaaaaa atttcttggc gtgttcatct
     9661 gattacggcg ttgatcaaac gaaaatggtt taaacgttga taaaagatgt ttaaatcctt
     9721 aatatttcca tgacaaatat aacaattgat gagataataa caaagtgaaa tttgaaatca
     9781 aaaaggagag cagatatcca tgaagggaat cattcttgct gggggcagcg gaacacgtct
     9841 gtacccttta acaaaggcaa catcgaaaca attgatgccg atttatgaca aaccaatgat
     9901 ttattatcca atgtctactc tgatgttggc gggaatcaaa gaaattctga ttatttcaac
     9961 gccacaagat acaccacgtt tcaaggaatt atttggaaac ggaaatgatt taggactgca
    10021 gatcgaatat gcagtacaag aaagtccaga tggattggca caagcgttta tcattggaga
    10081 agaatttatt ggagatgata gtgtctgctt ggtattaggg gacaatattt actatggtgg
    10141 cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat acaggcgcga cagtatttgg
    10201 ctatcatgtc aatgatccag aacgctttgg tgtagtagaa tttgatgaga atatgcaagc
    10261 tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat tacgctgtaa ctggccttta
    10321 tttttatgac aatgaggtaa tttctatcgc taaaggtatc aaaccttcag aacgtggaga
    10381 actagagatt acggatgtca ataaagcata tttggataaa ggaaaactat ccgtagaact
    10441 tatgggacgc ggatttgctt ggcttgatac aggaacacat gaatcattgc ttgaagcatc
    10501 tacctttatc gaaacaattg aaaaacgtca gaacttaaaa gtggcttgtt tggaagaaat
    10561 tgcttaccgt atgggctaca tcgataagga acaattgctg gcccttgcac agccattgaa
    10621 aaaaaatcaa tacggtcaat atttattgaa tttggccgct gaataaggag tccttacaga
    10681 tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt agaaatggac gtctttggcg
    10741 atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa atttgcagaa catggattga
    10801 aatatgactt tgttcaagac aaccattcac tatcagctga agctggtgtc cttcgggggc
    10861 ttcatttcca aaaaggagaa gctgcacaga caaaattgat tcgggtagtc actggagcag
    10921 ttttagatgt agtagtggat atccgcaaag gtagcccgac ttatggtcaa tgggacggat
    10981 ttatcttatc tgaacataat catcgacagt tgcttgtacc taaaggatat gcccatggat
    11041 tcgttacttt gacaccaaat gtgaacttcc tttataagtg tgataattac tataatgcag
    11101 aagcagatgg gggcatcgca tttgatgatc cagatttagc gattgattgg ccaattgatc
    11161 catcaagagc gattatgtcg gaaaaagatc accgtcatcc gacattaaaa gaatttgaag
    11221 cagaaaatcc atttgtttac ggagaaatct aagaattaag gagaaatttt cttatgaaaa
    11281 acatcattgt taccggaggt gccggattca tcggctctaa tttcgttcat tacgtggtaa
    11341 acaatcatcc agaagtgcat gtcactgttt tggataaact gacttatgca ggaaacaaag
    11401 agaacttggc tggacttcct agcgatcgcg tagaattggt cgtaggagat gttgcagatg
    11461 cagaattagt ggaccgtcta gtaaaagaag cggacgcagt tgttcattac gcggcagaat
    11521 cccataacga taattcatta aaagatcctt tcccatttgt acaaacgaat atcattggta
    11581 cgtatacact tttagaagct tgccgcaagt atgatgtacg ctatcatcac gtatctactg
    11641 acgaggttta cggcgatctt ccattacgtg aagacctgcc aggacatggg gaaggcgaag
    11701 gagaaaaatt cactgcggaa acaccatata atccttcaag tccatattct tctacaaaag
    11761 ctggttcaga tctgttagta aaagcatggg tgcgttcttt tggcttacgt gcaaccattt
    11821 caaactgttc aaacaactat ggtccttatc agcatattga aaaatttatt cctcgccaag
    11881 taacgaatat cttaagcggt attcgtccaa aattatatgg cgaaggaaag aatgttcgtg
    11941 actggatcca tacgaatgat cattcttcag cagtgtggct gattttgacg aaaggcagaa
    12001 ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga taataagacc gtgatggaat
    12061 tgatcttaga aatgatgggt caaccaaaag atgcgtacga ccatgtaaac gaccgtgcag
    12121 gacacgactt gcgttatgca atcgattcga caaaattacg ggaagagtta ggatggaagc
    12181 ctgagtttac gaacttccgt gatgggttgg ctgacacgat caaatggtac gaagaacatg
    12241 aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc atatgccaaa aatggacaat
    12301 aatacagaga aaatgtcact gtattaatgg aaaaacacat gtgaggcagg cgctcgcctg
    12361 tctctttttt aaaataaaaa tcaaggagcg gataatcata tgtttttatt aactggagga
    12421 aatgggcaac taggtacaga attgcgccat ttattagatg aaaaaaatct gcaatatgtt
    12481 tcaacagatg caaaagactt ggatatcaca gatgccgaga aaacaatggc ttacatcaca
    12541 gaattaaaac ctgatgttat tttccattgt gcagcttaca cagcagtaga taaagcagaa
    12601 gaagaagcaa aagaattaga tgagaagatc aatgttgatg gtacaagaaa tgtagcactt
    12661 gcagcaaaag ctgtgaatgc tcaattcgtc tatatcagta cagactatgt tttcgatgga
    12721 aaaaacaaaa atgtagaata cgaagtagac gaccaaacga atccactaaa tgaatatggt
    12781 cgtacgaaat tattaggcga aaaagcagta gaagagattt tagaagacta ttatatcata
    12841 cgaacttctt gggttttcgg gatctatgga cacaatttcg tcttcacgat gcaacgccta
    12901 gcggaaaccc gcgacaaact gactgtagta aatgaccagt ttgggcgacc aacttggaca
    12961 cgtactttgg cagaatttat ggtatatgtc atcgaagaaa aagcaccatt tggtatttat
    13021 catttgtcga acgaaaatag ctgttcttgg tatgaattcg caaaagaaat attgaaagat
    13081 acagatgtag aagttgcacc tgttacgtca gaagaatttc cgcaaaaagc aacacgtccg
    13141 cagtattcag tcatgagcct gaaaaagaca gaagagttag gatttgtcat accaacttgg
    13201 caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa tgaataagta atttcctttt
    13261 atcaaataga atttggagca tgatatggaa aaacaaacaa gaagtgcacg acgaaaagaa
    13321 aagccaaaag cgaaccaggc agattcgaat ttggtgcttg acctgtttct aaaactccgc
    13381 tatcttattg gcgttttagt catcgtggtc atcgttactt ttaatttaaa cggaagttca
    13441 cttggtgttt gggataaata tgtgtcgcaa agagacgatg ggaaaaaaac tgatgtgatt
    13501 tttggacaga atcgggaagt gcggtcagac gaatggctgg tgcagacacc tttttacctc
    13561 tcacaagctg aagaggactt tccgttggtg aacgaggatt attcattaaa cggacaaaac
    13621 atgatcattg cgtataattc tcctgcaaag gatattacgg ttatcggaaa accattcaac
    13681 tggggattct ttttcctcgg aagagatcga ggactttcct tttattgggc gatgaaatta
    13741 gtcgtcatgg tcttgcttgg attcgaagta ctgatgatat taacgaagag aaaaaaagct
    13801 ctatcgctaa tcggtgcatt tgcgctgaca ttttctccag cagtccagtg gtggttcatg
    13861 caacatgtgg gcgatttgat tttctttact ttgggactga tgactgcttt ttatcattat
    13921 ttctacaatc atgataaaaa atggctacga acgttgatga tgcttttggt ggttattttc
    13981 ggtattgggt ttattttagt gatttaccca gcccatcaag tgatgctggc gtacttgctg
    14041 attttttatt ttgttggcct gcttatttac tatagcaaga aagtttcatg ggatctgttg
    14101 gatgtagtgt tgattggagg ggcagtttta tttattggcg gagtcatggt tcatttctgg
    14161 ctaacgtcaa aagacgcatt gttagcttct ttgaatacct tatatccagg aaaacgggta
    14221 agtactggag gaaagtggac gattggcgaa tttttttctt tccttacaaa ttggaaaatt
    14281 ccttttgaag atatcaacta ttcgaataac tctgaagtgg ccctgttcta tcactttttt
    14341 ccaactgtat tcctagcaag tccatttgtg ttatttggca aaaaagatag cgaacaaaag
    14401 ttactgggac gtattttgat gattttttgt ctgttttcta tcttttggat taccgttggg
    14461 ttgccaaaat ggctagcaga aatcactctg ctgtcttatg ttcctccatt aagagccatc
    14521 cttactttta gttttgcggc ttgtttatta tcgatctggt ttatcgctta tatttggaga
    14581 gaagatgtta ttcctatttg gtataaattc attttgttgg cagtaaatgc atggtcttat
    14641 ttctatgcga ttacgcattc gaaaatagat aattattttt cggattttga aaccatcgca
    14701 gttgctgtgt tgggaacagt gattttagca tttgcattat ttggctggag acgcttgttt
    14761 tacctcgctt ttgccgcctt agttatcgta tctggctttt tcgtcaatcc agtcgtagaa
    14821 ggtacaggag cgatttttga aaaaacactg gcaaaagaaa tccaaaaaat cgatcaacaa
    14881 gatcctggta aagtttggtt gtctgaagat gaattatata acttcacccc aacattggga
    14941 gtgaaatcct tcaatacagt acgcttttat ccagatatag ctgcatggaa ggaaatcgat
    15001 ccgaaagaag aatacgagaa gtattataat cggtatgctc atacaagagc ttttatcgct
    15061 aaggaagata caaagttcat tttagatcgt ccagatatgt tttcggtcac gttgaatttt
    15121 gaagacgcag aaaaattagg gatcgactat gtgatcagta aacgaccatt aactgattac
    15181 aaccaattat atgaagcgca gttcacgcag ctatatggac cggataaaga cggttatatg
    15241 atttttaaag tagaatatcc ggattatcca gatgtaccac aaacacaaac tcaggaaaat
    15301 cagctagtcg tacagtaata ggctagctga gaataatcct gaaatattag tagaaaggag
    15361 agtggagata attcaagcaa tcgtacaaaa atttgtcaac aaaatgagtg tcggtttctt
    15421 gcttttgttg ctgacgctag tcttttttgt ttggacagca gggttaggtt ttccagcaac
    15481 tttgtttata tataacaata gttcattact tatcgctttt agtgtggcta ttttgctcat
    15541 tttaaatgtt tataaagcaa aaggcgtcga ttttctttat ctaggtgttg cgcttgccct
    15601 tttcattttc ttttcttact ttcgggaatt aagaaatgag tctttatttg gagatttact
    15661 gtttcctttg attattttat tttgtttagt aattaaatgg atcgagtgga caaaatggga
    15721 tcgcggtatt tatctgattg tctttacggt cttcctcgga atcacgttat atcgtgtatt
    15781 tacagagatc caagtaccag aaggacaaag catctgggct ccaggcaatt cgctttctga
    15841 tatttggatc aatacgaata caatcggaag ttctttgatg actcttgctt tattgatcag
    15901 tggatttgcc agttcttttg aacgatggta tgtacgaatc atcggtgcag tagcagttgt
    15961 tgcagctttt ctcgggattt gggtctgcca atctagaggt gcattagtcg cgttgattgt
    16021 ttttgcgata ttggatcttt tacctaaatc gttgatgcgt gtcattcgtg cgccatttat
    16081 tgcttacacg gttacgattc ttttagcttt gccgatttct tatctggcgg ctgtctctga
    16141 aaaagtcaat ttgtttaccg gtcgagaaga tatttggcat aaattctatc agacgctagg
    16201 agaaaaatct gaacaagttt tactaggaat gaaaacattt atcttccaac gaggaaacca
    16261 atttttagga aaccacaata gttataattc tattttgaat atctatggat tgataggatt
    16321 tgggattgct actttgctgc ttatcctttt tattggtcgc ttaacgttga aagcagattt
    16381 atccaacggg cagatgactt ttatctgggc cttttttgcg gtgatgatgc agtcatttat
    16441 ggaggataca ttgacttcat acccatgggt tccgattatt tatatcctgt tggctatggc
    16501 cgttcatcga tatgatgaac cagaagttgc ggaggaattc tatgttatgg aagaggcata
    16561 tgacgatatg acttatgatg atacatctta tgaggaacaa ccagatagcg ctcattcttc
    16621 caggatccaa cgctatcatt gataggcaca aaat
//
LOCUS       DAFEML010000052        16596 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFEML010000052
VERSION     DAFEML010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.053"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(8..1375)
                     /gene="nhaC"
                     /locus_tag="LP468_002001"
     CDS             complement(8..1375)
                     /gene="nhaC"
                     /locus_tag="LP468_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL2081515.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1484..2905)
                     /locus_tag="LP468_002002"
     CDS             complement(1484..2905)
                     /locus_tag="LP468_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2081516.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3148..5025)
                     /gene="tdc"
                     /locus_tag="LP468_002003"
     CDS             complement(3148..5025)
                     /gene="tdc"
                     /locus_tag="LP468_002003"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2081517.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5316..6572)
                     /locus_tag="LP468_002004"
     CDS             complement(5316..6572)
                     /locus_tag="LP468_002004"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL2081518.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6684..6889)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7152..8453
                     /locus_tag="LP468_002005"
     CDS             7152..8453
                     /locus_tag="LP468_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2081519.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8522..9121)
                     /locus_tag="LP468_002006"
     CDS             complement(8522..9121)
                     /locus_tag="LP468_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2081520.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9375..10256
                     /locus_tag="LP468_002007"
     CDS             9375..10256
                     /locus_tag="LP468_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081521.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10269..11879
                     /locus_tag="LP468_002008"
     CDS             10269..11879
                     /locus_tag="LP468_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL2081522.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(11956..12615)
                     /locus_tag="LP468_002009"
     CDS             complement(11956..12615)
                     /locus_tag="LP468_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2081523.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(12898..13563)
                     /locus_tag="LP468_002010"
     CDS             complement(12898..13563)
                     /locus_tag="LP468_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL2081524.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13710..14315)
                     /gene="dhaL"
                     /locus_tag="LP468_002011"
     CDS             complement(13710..14315)
                     /gene="dhaL"
                     /locus_tag="LP468_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL2081525.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14343..15353)
                     /gene="dhaK"
                     /locus_tag="LP468_002012"
     CDS             complement(14343..15353)
                     /gene="dhaK"
                     /locus_tag="LP468_002012"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL2081526.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(15328..15774)
                     /gene="dhaM"
                     /locus_tag="LP468_002013"
     CDS             complement(15328..15774)
                     /gene="dhaM"
                     /locus_tag="LP468_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL2081527.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            complement(15813..>16596)
                     /locus_tag="LP468_002014"
     CDS             complement(15813..>16596)
                     /locus_tag="LP468_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2081528.1"
                     /translation="KNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIAC
                     SVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEFG
                     HLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFKS
                     ITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNKV
                     SETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
BASE COUNT         4742 a         3462 c         3010 g         5382 t
ORIGIN      
        1 ccttccttca attttttaca cgtcgacgat tcaataaaaa accgcctaat attgtaaaga
       61 caggtgcaag aatcgagaaa aaggcgaatg gcaagtaatg caacgcgcta actttcatcg
      121 ttcccataat gaatgtgccg ctgactcccc acggtacgag agaattgacg gtcgcacctg
      181 aatccgctag tgttcgtgtc aaataggttt ttgataagcc aacgtcatca aaagaacgct
      241 tgaatgtttc tcctggaaga atgatggaca gatactgttc tccaacgatc agattgattc
      301 cgatacagct caaggcagta aacccgacta aacgagaagg tcggtccatc ttttctttta
      361 attcttgaac gatggtatca acgatcagat atttgatcag taacccacct aatgccaatg
      421 caagtaaaat caaactagca gaacctaaca tactcatgat cccgcctcga gaaagcagtt
      481 catctagctt tggatcaggt gtatttgcga cataaccatt catcaagatg tctgctgctt
      541 ttccgaccgt caaacttttc tcatggataa aagaaagaac gagagcagct gtcgatcccg
      601 ctagtaatgt agggatagcc ggaatttttt tgattgcccc cccaaataaa ataactagtg
      661 gaatcaatgt ccaaggagag atccaaaagc tcgctttcat gttttggatc atttcattga
      721 tactagctag atcggctgaa tgactgttat gtcctaatat cgtataaaaa atcaacgaaa
      781 ggacgaatgc tgggaaatcc gtataacgca taccagcgat atgttcgaat agattaactc
      841 ctccaatacc cgctgccaag ttggtcgtat ctgataaagg cgagcagtta ttccctaaaa
      901 aggcaccgga aacgactgcg cctgtagtca ttgcatcatt gaatccaagt aaatgaccga
      961 tccccaaaaa agcaattcca atcgtcgaaa tcgttgtaaa tgaactgccg acagtcactc
     1021 cgacaattgc acaaacaaga aatgctgtcg gtaaaaagaa acgcacagaa acaagtttaa
     1081 atccataaac cataatcgta gggatggttc cagataaaat ccatgaagca actaagacac
     1141 caatcaaaag aaaaatcagg attggaatga tccctggagt gattcctttg atgatcccgt
     1201 catggatctc atcccatgtg aactttttaa atctgccata aaacaacaaa cacatgaaag
     1261 ctgcaaggat cgggatatgt ggcgagagct ggaatccgat gatcagtact cctaggagtg
     1321 ccaacaacac gatcaataca gcgatacttt cttttaaaga aatattttta ttcatcgtcg
     1381 atctcctatt tcaaatgaaa aggccctgcc atgaaaaaac tattcacttg gcaggacctc
     1441 ctactaaatc agcgacaaaa cgtcggctga aagacttatt tttttatttt tcttctaaac
     1501 ttttttctac ctcaatcccc caagaatctt tcttgaagtg attgatgatc aatggaataa
     1561 cgaacatgac cactgtgata gctgctacta ataatgcatc actcaatgtc gctgtaccta
     1621 atgtagcaaa tacgacaacg atgatagaga agatcagcat gcagctgact acccaagcta
     1681 atccgtttcc gtttttacca attcggtaag gacgttcgaa ttctggatgt ttcttacgca
     1741 ttttaagcaa tgaaacagca atcaaaatgt acacgataca ataaataaca gttgtagcat
     1801 ttgtaagtgt caagaataca gcacttacgt catccattac accataaagc aaagcaaata
     1861 atgaaataac gattgattgt gttagaacga catttctaga tacgccgtat ttgttttctt
     1921 tatggaatcc gaattttggt ggaaggaatc cttcacgagc tacttggatg attgtttttg
     1981 atggtccagt aacccaagct gataattgta aaagcacacc aataaatacc atgaagctga
     2041 agatatttcc gatcacttct ggtaagccta ggatttgaca gtcaatcaag ataggctgcg
     2101 tgatatttgc taattccatt tttccatctg gtacgacatt tgctacaagc atcgcattga
     2161 tgacattcaa taaaactaat ccgatcaaag cgataaatac gccttttgta taattttttg
     2221 ttgcgtcttt caaacgaggc atgtaaacag aactcatttc gatcccaaca aaaataaatg
     2281 tgataccagc taagtatttc aatgaatcaa tatgttccaa gtcagggaaa gcttttgacc
     2341 atgaaaagtc acctagatag ccgtttgaga ctagtccgac tttgaaggct gccaaaacac
     2401 ctaaaacgaa catgatgact actgggatat atacccctag ccatacaccg atgttcccgc
     2461 cgacttttgc catatcgaat ttcaagttca agatcgtgat gatccagtag ataactaaaa
     2521 tacaacctaa aacgaaccag tgattattgc caagttctac attaccaaat gtgtttccta
     2581 acaatggtcc taaagtagaa gcgaccatta ccatacctgg gaacatttgc acccataata
     2641 gccatgcaac gacaaatccc catttgctgc ccagtgctgt ttttacccat aactgaggac
     2701 cgccttcttg aggaagcatc gtggaaagct caccggaaac cattgatatc ggaccggcaa
     2761 aaaacaaaac tgcaaaaatt gaataaaaaa tcaatgtcca accgactgcg gctaacgtag
     2821 gaatactccg aaccgttgca cacagtgcca ttgtcagacc gataaaggtc ccaagaccca
     2881 ttttacttac ttcagattta ctcaccgttg acactctcct tgattttttg gataaaataa
     2941 cggtgtcttt gaagtagttt cagcaataaa cgaaacaatt cagcgaatat ttgaggggat
     3001 tctttgagtt tattgcttga agggtttctt caaagacaac ctcaaaacaa agggatcgaa
     3061 gagcttaggt ctccccttgc tcttcagatc caaacatgcg tcagaaacag ttagtattca
     3121 agctgttttc taacatgatt accttgctta ttttgcttcg cttgccaata attggtctgc
     3181 gtagattttt tccaattttt cttgaagagc tgctttgatt ttttcagcat attcttcaaa
     3241 gtgttcttct ttgttcatgt atggtgtcat tacgctggca cgcaatacag ttacttttcc
     3301 ggcacggttc cattcttcat ctgagaatcc tagttggttc acaaattgta atgggctgtt
     3361 gccatagtct gggatagcaa agtcagtatg tgaagttaag aactcattac cgtaaatgct
     3421 tcctttcacg tatgaagaat aatcatatac gtcatggttc aatttattca ttgcaactaa
     3481 gtcatcgttg cctttttctt tgaatacata gtctaccata ttgaaatctg gataagttaa
     3541 tggatgaact tcgatttctt tgtctcctac tttaaatgac aagtcattca agaagttgta
     3601 gaaacgatgt gcaccttcga ttgatgcacc cattaattta ccatatcctg tgacattcaa
     3661 aggtaagaca tggtgtgctg cccaaacgct ggctgctgtt gcccctgctt ttgaaccttc
     3721 caagatataa gccccaagta atgctgggat atctgcgcct ttttcaaata catatgtcgc
     3781 aaagtaagag ataacgtctc tcatgcggat atctttgatg acgataccac cggcagaata
     3841 tggaacatag cccattttat gtgggtcaat cgttacagat tctgcttctt cgattgcttt
     3901 atacgcactg tgtacttctt ctaagatata atctttgttt tctgtaaaga cattgtattt
     3961 gtaatgaaca tcttttaaat cttcaaatgg aatgaagttg ttgtcttcgt ctaagaaaat
     4021 cgcacggccg tatccgccat aagcagcatc tacgtgtaag tagaagtaaa taccgtcttt
     4081 ttctaatacg cgacgcaatg caacgatttt atcgataccg tcgattgctc cttcttctgt
     4141 tgatcctaca acaccgacta cacctaggat tggtgttttt tcagctgcta gaccacgaac
     4201 gattttttca agttcgttga tgtccatgcg atagttgtgg tcaactggca ctggaatcac
     4261 ttggtctaaa ccgataccga tgatgtcggc agcttttagc catgaatagt gtttagtttg
     4321 tggaaccaac cattttccta atttttctaa atgttttccg ctacgtgctg agtgagcttt
     4381 gatttcgtcg attttttctg ggacgctgtc taacagattc atgatttctt ctgttgacaa
     4441 gttcattaat tcccaatcgc tttttccagc aactagttca ggtgtcactt ctttcattgc
     4501 aagcggcaat gatttgatgt tgcgggcata ccaaagtcct tctaagtttg ctaaagaacc
     4561 atcagcaacg atgtggcccc agccatcttt atagctcatt aattttgcaa attccattcc
     4621 tacttcttct tccatttggc ttgttgcagg agaagattca taggcaacgt tattaccatt
     4681 ccatagcata gcaaaattgt acgctagtaa agatggcatc aatgtttcag agttcatatg
     4741 accccagtaa cgtccggcat tatgccaagg aacggaatgg gtacgcatcc gcgctgaaat
     4801 ttctgataga acatcctttg ttttattcac agtgtgttca aaactagcac tgcttttttc
     4861 ttctggcgta ataataggca tgtcttgagg catgtagttt tgacgccagc ctaaatgttc
     4921 atccaccaat tcattcaaca aagctttata gatttggccg ttctcagctt tgtccccaat
     4981 gaatagggca tttaggttta gatctttcga caatgattca ctcatagtga aaccctccta
     5041 aaaaaatatt taaattttgt cgagccctac attacacctg ttcttctatt ctgtaaacta
     5101 agttttggcc tgatttttaa tcatatttta atatgtatca attatccgaa ttgttcacac
     5161 ttttgaaata attaaaaaaa acgagggaat ttacaaatgt aaactccctc gcaaagattg
     5221 tattaacgac aaccagcgtt ctattttagg atgggtttca aaattggaat gttgtaatag
     5281 tatttccctt tttcaaggta aaaacttact aaattctaat caattacttt ggccaaaaag
     5341 taatttttct taccttttcg aataaccaca aacttaccat cgaattcatc ggatggattt
     5401 atgacaaaat ttaaatcggt aacgcggtca ccgttaatac ttatagctcc gtttgaaaca
     5461 tcttcacgtg cttgacgttt agatggttca atttttgtgg aaacaagcag ttccacgata
     5521 ttttcaggtg tgcttgaaat ttcaacgttc ggcattttac cgaatccttg cgcgatttct
     5581 tccgcattta gttctttaat atttccagag aacaatgctt gcgttatttt ttgcgcttct
     5641 ttcaagtctt cttcactatg cacaaatctt gtaacttctt ctgccaaacg gcgttgtgct
     5701 tcacgtttct caggttctgt ctctactttt ttcgctaagt cttcgatttc ttcttgagac
     5761 aagaaagtaa agaatttcaa gtatttcact acatcgcgat catcttgatt caaccagaat
     5821 tggtagaact caaatggtga agttttcttc ggatcaagcc aaacggcacc gcctgcagtt
     5881 tttccgaatt tcgttccgtc agccttcagc atcaatggga tcgttaaacc gaacgcttct
     5941 gcttctggtc cttctaattt tcggattagg tctaatccag ctgtgatatt tccccattgg
     6001 tctgctccac cgatttgcaa ttgcacatcg tatgttttat gcagatgcaa aaagtcgata
     6061 gattgcagga tttggtaagt aaactctgta aatgagattc ctacttccaa acggctggca
     6121 acgatatctt ttgctaacat cgtgttgatg ttgaagtttt taccgtagtc tctcaaaaat
     6181 tcaagtaaag agatttttga caaccagtcg tagttgttca caaatgtgat atttgcatct
     6241 ttaccaaaca attttctcat ttgattggaa agtgcgtcca cgttatgttg cacttgttcc
     6301 atcgtttgca acacacgttc tgttttgcgg ccgcttgggt cgccgatcgt tcctgttccg
     6361 ccgccaatca gaatatatgg atgatggcct gccaattgga atcttttcat catcataaat
     6421 ggaatcaaat gtccgatatg catcgaatca ccagttggat caacgccgca ataaagtgaa
     6481 atgctctttt cttcaacgag ctcgcgaagt ctttcttcgt ttgtttgctg attaatggcg
     6541 tcgcgccaag ttaattcatc aataatattc attttactga cctccgtgta gtttttttat
     6601 gaaagcagga acctgctagc atgtgtaatt aattatttct tcaggatagg ataggaaata
     6661 aaaaaagtcc cttggcatat aagccaaggg acgaaatctc gcggtaccac ccaatttgta
     6721 tgtctagata tccaacatac ctctcgaaca tttaacgctg tcgcgtggca atcactgcca
     6781 aagactcctg aaatgtaatt cgctttaaag catgtactgg tttgcagcga ccaccagctt
     6841 tctgaaacat tggctttaac aactacttcg tttcgatctt cgtcttgtta ttattaatat
     6901 gtgtctatca tagagcgcaa ctttttcttt gtcaacagaa aaaggatatt ttttttaaat
     6961 tcctcatttt ttcttttttg aatccgctct aattccgaac attttatttt caattattgt
     7021 taaaagaaat aactttttct gtattttttc tgcaatttat cgagaagtca ctttactttg
     7081 cctcttattc tttcttcgtt acaataagga atgggacaag taaaaaaatg aaaaagcaag
     7141 ggacgaggta tatggaaaaa aagcaaaaaa ttattttagg agccacttct gctttaacta
     7201 tcgttatttt aattctaagt ttgttttttg tcatccgatc atctacaaaa aaagaaccaa
     7261 tcattcctga aaaaaaaata acagaaaaag caaaagaacc gacagatgat aagcaacaac
     7321 tagttactca agcaaaaaat ctggctcaaa gctacgatta tgaccaagcg attgcgttat
     7381 tggaaaaaga tagtaagaac ggatctactg aaacacaaca gcttcttcaa acactaaaaa
     7441 aggagaaaga acaactgatc gactggtctg atcctactca gatctctcat gtctttttcc
     7501 acagcttgat cgtggacccg caaaaagcct tccactctca acaggcacaa ggatacaaag
     7561 attatatggt gactgttgaa gaattcaacc gttcgatcga acaactttat caaaatgatt
     7621 ttgttttagt taatttgaat gatttgatcc aaaaagacga acaaggaaat ctttccttta
     7681 acgggcttgc gctacctgaa ggaaaaaaac cattggttct ttcacaagat gatgtcagct
     7741 attatgaata tatggataat tccggttttc ctagccgatt ggtcgtatca aataacaatg
     7801 aaatcaaaaa tgtctataaa gagaaagata aagaagaaat cggtgacttt gacatggttc
     7861 ctctgatcga tgcctttgtc aagaaacatc ctgatttttc ttatcgaggc gcaaaaggta
     7921 ccttggccct gacaggttac aacggagttt taggttatcg aacatcaaaa tctcaatatg
     7981 gagacaatga aaaaacaaaa aaagagatta aagaagctaa aaaagtggcg gaacagttga
     8041 agaaagacgg ctggagcttt gcttcccata catggggtca cttgaatatg actcaagctt
     8101 cactagaaga tgtaaaaaaa gacaatgaat tgtggcagca agaagttgca cctatcctag
     8161 gaaaaacaaa tattctgatt tatccatttg gtgcagacat cagcgactgg cagccttatt
     8221 cagcagaaaa tcaaaaattt gcttacttga agagtcaagg tttcgatatt ttctgtaatg
     8281 tcgatgcttc tacaccagct tggggacaat taggtacgga tttctatcga aatgctcgga
     8341 tcaatatcga tggcattcgt tttcaatctg atttagacgg aaaaaatcct attcttgatc
     8401 cattcatcaa tgtccatgat gtctatgaca aagaagcacg cgaatctgct tgattttacg
     8461 tcatttatga accaaaaaag ccgaactgac attttatcgt cagtttcggc ttttttatgc
     8521 tttatttctt cttcggtgcg attcccttga tcaggacttc tgtccattct gctgtatatg
     8581 gaagcagttt tgcgtatatc tccggcttag aaattccttc taccattgct tgaaaataga
     8641 ggatcaagaa ctcatccgaa tatttcaaat ccacttttcc ttctttccgc cctcgatgga
     8701 aaagatcaag catgatactg aaactttctt gcgtatacgc atccatcgcg tcagaaaatt
     8761 cttttttttc tttttttgta tagtatgtca tcaaatcgat ataaaattgt ttgttcactc
     8821 gattgagata acggattttg ttttcactca tggcaatcag tgtttcttca aatggaagat
     8881 tttccgcaat caacgctttc gcttcttgcc ctaaatcatt cataaatgca aaaaatactt
     8941 cataaatcag cccttccttg ctgccaaaat atttaaaaat cgtcgcttta cttacctgag
     9001 cgttctcagc taccttatcc attgtcactc cagcggttcc tatgtctgtg ttcatcaagt
     9061 caaaagctgc ttgtaaaatc tctttctttt tctcttgtgc tctcttttca aaaccgttca
     9121 tttgtagagc ctcccgtaat tttaaacttt tataatatat atagttcaaa tttattctga
     9181 ggtttattat aactatctat tgagaaagta tcaagctagc aattccttgt ttatgaattc
     9241 attgacagaa atttataaaa agaatattat gtactaaaat aataaaaaaa gttttataaa
     9301 aaggtataaa acctttttat taaactattt aatcttgttt agtatatatt tttagaaaaa
     9361 ggagtggggt ttttatggca gaaatcgtca aagtcacaca tttgaaaaag agctttggtc
     9421 gtttcgaagc tttaaaagat gtctctttca ccgtacattc aggtgaagtc gttggattta
     9481 tcggaccaaa tggttctgga aaatccacga cgattcggac acttttaggg attataaaaa
     9541 aagacggcgg aacggcaacg atttttgggc aagatgtatg ggaagatagt ttatctatcc
     9601 atgaacgtct ttcttatgtt ccaggcgata tctctttgtg gggaaatttg actggaggag
     9661 cgatcatcga tctcttcatg aagcttcatg gaaaagggag tgctcaaaaa aaagatgaac
     9721 tgattcaacg tttctctctt gatcctaaga aaaaagcaaa aaactattca aaaggaaatc
     9781 gccaaaaagt gggcttgatt gctgctttgg ctgttgattc ggatctctat ttatttgatg
     9841 agcctacttc tggtttagat cctttgatgg aaacgatttt ccaagaagaa gttgaaaaat
     9901 tgaaagaaca gggcaaatcc atcctacttt cttctcatat tctcagtgaa gtcgagcgac
     9961 tagcggataa agtcgtgatc atacgcgaag gaacactcga tgaagaagga acactcgatg
    10021 aattgcgtca tttgactcgt tcgaccatca ctatagaaac agaagcagag aatagtcact
    10081 tagcacaatt gaacggtgtc catgactttg tgcaaaaagg tcacctcgct caatttgctg
    10141 ctgataacga agctttcgat gtgattttag ctgaagcgtc caaattaggt gtgaaaaaat
    10201 ttgaatctat tccaccgact cttgaggatt tattcatgag acattatgaa ggatgaggag
    10261 gaagcgaaat gactgataaa ttttcacgct ggtccaccct tttttctcaa aaccttagcc
    10321 gtgactggaa aaagatcctg atatggctag tcggtgtcac tgctttttct ggtggttttg
    10381 tccctgcgtt tgaagaattg acttccggac aaggattagc tggattatac gaaaccttgc
    10441 aaaacccggc aatgattgca atggtcggac caactccagc ttcgaatgct gctgagtata
    10501 ctttaggagc gatgtatgca aatgaaatgt tgcttttttg cagtttgttt gctgctgtga
    10561 tctctgtttt acacgtggtg agccaaacga gaaaaaaaga agaacttggt ctgattgaac
    10621 ttattcgttc ctttcgagtc ggacgtcaag caaactcttt agctgtcatc gctgaaagta
    10681 ttctgatcaa tttgctttta gcaatatcga tcagctgtac gatgattttt ttccaagcgg
    10741 attcgatcac tgcagaaggt gcttggcttt ttgggctatc tgtaggtagt atggggattt
    10801 tggggagtgc cgttgcactg tttgctgcac aactgatgcc aagttcagcc agttcgaatg
    10861 gtctgtcttt agcgttttta ggtggacttt accttctacg agcaataaca gatgtagctg
    10921 attcctccct ttcgatgtgg aatcctttag gctggtctta tttgacctat ccatttacaa
    10981 ctaacaactg gattcctttg ctttatttgt ttttgttcag tctaatcttg ataatcagtt
    11041 catttgtttt agaggaacat cgagatttga acaccggcta tatccccgaa cgtgaaggaa
    11101 aaccgtatgc taaacgttct cttttatcct tgcgtggttt attattctat ctaaataaag
    11161 ggatgacaat cagttggctt atcacttttg gtttgatggg ggcggcatac ggctctatct
    11221 acgggaatat gcaacagttt ttagaaagta acgacttaat gaaacagatg tttatccaat
    11281 ctggcgtctc aattgaaaaa aactttacaa gcacgatcat ggtcgtcttg atttgtctag
    11341 ctgctatttt accaattgct agcatcaatc gtttatttac agaagaaacc cacggacgta
    11401 tgaatcagct gttcgcaaca aaaatttcta ggaaccaact ttattggacc aatatgttac
    11461 tagctattct atttgctata ttggcaatcc tgattagttc tggtgcacta gggctttctg
    11521 ctttggcttc gatgaaggat gcgaaagaca tggatctatt gatgtttctt aaagccgggt
    11581 tcaatttcct gcctgccgtt ttagtgttta tcggaattag tggctttcta ttcggatggc
    11641 ttcctcgaat cggtaaactt gcttatatct acttagctta ctcctttgca ctcaattact
    11701 ttggcggaat tttggattta ccagaatggt tttccaaaac agctgtccct agctgggttc
    11761 cacggatgcc aaacgattct tttgatcttt ccgtgttcct tacgttatca tgtatcagcc
    11821 ttgcactgtt cgtccttggt tctattggtt ataggcgaag agacttacta gaaggataat
    11881 aaaaaagcat gtacaatttc atgctagcct ccaaatctgg gtcaaaaatc caacatttgg
    11941 aggtcatttt tttatttaca agtcttctaa ctgctcttta tcaatgatcc agacttctcg
    12001 attctttctt tttacataac cattctcctc taataattta aattttctag ataaagtttc
    12061 gggggtcgta ccgataaatg cagcaagttc tttcattttc attggcagga aaaagtgatc
    12121 cttccctgtc gctttagcta agtcaagcag atagacagcg actcgttctt ctactttttc
    12181 catcatcaaa aaagttgtct gctgctgtac ttttgttaat ttctcaacgt tgattgctaa
    12241 aagtttcaga ctaagggcgg gataatgcag taagagttcc gagaaatctt tttgtctcaa
    12301 tatgcaaatt tccgtttttt ctagtgcttc gccaaataaa gactcatttg gaacgcctag
    12361 caactggctc tctccctcat atccgcccgg ctctattact cgtaaaagct gttcctttcc
    12421 gctagcagat aattgataca ctttcatact gccggaggcc acgatcacta attgaggttc
    12481 tccattcggc gcaagaatct gttctccttt ttccacatag tgatgtttga caagtgcgtg
    12541 tactttttct tgatcttgct gtactaagtg attgaacaaa ggaacaaatg aaacacataa
    12601 atgatcatga ctcataatct ctcctccttc taaacagcta tttctaataa agaaacataa
    12661 cttcccttat tccaactgat aattttcttt tatcatagca taaacgtcaa gcgaaccaga
    12721 taccagcaaa tagagtggat ttctttttgt cccttgcttt attttccttc ttttgagacc
    12781 ttaagtaatt gattcctatc aattttttaa atatttactt tttgaataat caaaaacaaa
    12841 ccttcactcg caagccgaga gtaaggtttg tttttcgcat tgcttatttc gtgttgtcta
    12901 ttgaaatttt tccgcaccta gcttttgata tagtggtgct agttcttgta aggtttcagc
    12961 ggttatttgc tcaacgtgtt cgatttcttg cggatagaag aatagtttac ccatttgaaa
    13021 ggttcggtct ctcatcgctt ttttcaactc ttcttgtttc tttgtatcgg acaaatagtc
    13081 agacaaagct aagtggtcgt caagttcatg ttctggttgc ggccatatgt aataatcctt
    13141 gatatcgact gttttgctcc actctttcag tatcgcaagc aactggttat acgctgcaat
    13201 gctaccatat cgttcttcgc ttttataatg ttggtacatc aaatagattt ggtattgttt
    13261 ttgattcaac aaaactgcta gacaggcatt ctcgtcttga cgagattcgc ttcggtacgc
    13321 gctccaaaaa tgactgcgta aattccagcc attcgtccag ctttcgattt taggtttgct
    13381 catgccgtac atatcaggca aaagtgcagc tgtctggagc tgaatctctt tccatttttg
    13441 ccagtgttct ttatattctt tcttgatttg ttcaatctta tctgttggat ggctctcttt
    13501 gagctgtttg aatgcgtaga ttggtcgatc aaacaactga taatctgatt ttccaagttc
    13561 cattgtttcg cctctttccg ttatcttttg tattctacct gaattttgcg atatggacaa
    13621 atagaggttg tgaaaaagct gttctgcatc aagtcataag aacagccaaa caaaaaactg
    13681 cgatgagcat caccgcagtt ttattgaact taaggttgat tgatcacatc taaaagcgtt
    13741 gaaaataaaa tggcactaga agcagctcct gggtcgatat gtccgattgc acgctctcct
    13801 agataggaag ctcgtccttt tttagctacc aagactttgg tgtgttcttt tgcctggtca
    13861 atgatttctt ttgttaaatt ccctgccttc aatgcctctg tgactggcag ccaaacatct
    13921 aacatcgttt tatcgtcagc ttctgccttt cctcggcttt gaatacccgc tgttccctgc
    13981 tcgatcactt cgcctaattt ttcttgagaa tcaatagaat cgacctcttt tgtcgctttc
    14041 atcatgttca tgaatgcaga tccgtataac ggaccagaag ccccaccgac tttcgatatc
    14101 atcgccatag agaatacttt gaatgtatcg ctgattgttt caggatgatc ggcttgaaaa
    14161 gcttcttcat aagctgaaac ccctcttccc atgttatttc catggtctcc atcgccaatc
    14221 ggggtatcta gatcactgag atattgtttg ttctgattga ttgcctctgc aaattgcgtg
    14281 agccattctt ggatttcttg aacggttagt ttcatattat caccctttta tcttgagatt
    14341 ttttaccatg aaatcgtctg tacattgctt tctaaagaat ctttccattg tgtctccgtc
    14401 aagtcgatca gtgttagaga aagaccttgc atatctagtg aggtcataaa attaccgact
    14461 tttcggaaaa ctacattgac gcctctttct tccaacagag ctaaaacatc attcatgaac
    14521 acgaactgtt ccatcaaagg cgtcccgccc attccgttga ctagtacacc tgcttctttt
    14581 ggtaaattcg agtaatcatc taaaatctta gtaacaagtt cctttgccag tactttagaa
    14641 ggctgcatct tttctcgacg atagcctggc tcaccgtgga taccaacacc atactcgatc
    14701 tcatcttctc ctagttcgaa tcctggtttc cctacttctg gtacagttgc tgctcgaagc
    14761 gctagaccga tcgtcttagt tgcctgtacg accttttctc ccagttcttt caactcagct
    14821 agggaagcac cgtttcttgc tgcatcgccc acgattttgt gtacaaggac agtacctgca
    14881 actccgcgtt ttccagcagt atacgtacta ttttcaacgg cgatatcatc atctacgatc
    14941 acactttcta cttcaatatc gtccatagca gctaattcct ttgccatatc gaagttcaat
    15001 gcatcccctg tataattctt aacgatcagc aaaactcctt ttccactatc ggcttcctta
    15061 atagccgtct gaatctgatc tggagttgga gaagtaaaca catcaccaag caccgctgca
    15121 cttaacatcc cttcccctac aaacccggca tgggatggtt catgtccgct tcctccacca
    15181 gaaaccaaac caacttgttc cgctttctga ttcttggcta caacacggga agattctaca
    15241 cgatgaacaa gttctggata gctttttact aatccttcca gcatttcttc gacaatattg
    15301 cttggatcat tcatgatttt tttcaattta ttcccatcct ttctttccgg cattttgtgc
    15361 ttctgttaag atttgctgag tatcatctgt tataccggca gtgatggctg ctgcaaaagc
    15421 tccttccact aaaggcgcat ccaccagatg ataacgttgc tgctgctctt cttccaacat
    15481 gtcttttgcc agttccgagt tcaataccgc gctaccgata tccgcaaaaa caaaataact
    15541 agctgcatcg cttgattcat tgactgcttc tacgattttc atcgggtctg atccgatctc
    15601 gccatttatt ccgccgagag aaaaaatttg cacctcttcg gatttttgca tctgctcaat
    15661 catttcttta ataccatctg ttactttttg actatgagaa ataagcaaaa tacttttttt
    15721 cacaagaatc ttcctttctt ttacatagtt gctaacgatt ggtttcgctt tcattaatga
    15781 acaattcaag tatataataa atttttcgtt tgtcaaatta agctagacaa atcatcttta
    15841 cctacgtaac tcaaaaatac ttccaatggt gtgcgatagt gtaatgattt tctaggaata
    15901 tgatttcgtt ttgatgccac cgattggata aaggtttcgg ataccttatt aaaatccata
    15961 gctttatata agccatcttt acgtaataag ccattcgaat gttcatttag tcctcgttga
    16021 gaaggtgttc ctggatcagc gaaataaatc gaaatatcat tggtattact aatctttttc
    16081 caattcgaga actcttttcc acaatcaaat gtgatggatt taaacaagtg tttcggtaca
    16141 gattgaaacc attgattcag tctattctca atatctatag cttgcctacc agcgggtttc
    16201 aaggtgatga tcactttaga taatcgctca actaacgtga tcaccgcact tttatgtttt
    16261 ccaccgacaa tggtgtcacc ttctaggtga ccaaactcat gattgaactg tatataatca
    16321 gttgttctat cctgaatcga acggcgaaaa gcttgttttc ctcttttttc tttatgtccg
    16381 tttggttttc ttttcccttt cattggtaaa tcgtgagggt caaaggtttt atctttaaac
    16441 atccgatata gtgtacgtac cgaacaagca ataggaaact ctgctcgacc aataaggaca
    16501 tctggagtcc acccttgagc cacctttttt tgaatgtatt cttgttgccc atctggtaac
    16561 acaatcggac gtcttccgca gttacgtttg tttttc
//
LOCUS       DAFEML010000053        16460 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFEML010000053
VERSION     DAFEML010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.054"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(283..1167)
                     /gene="rsmA"
                     /locus_tag="LP468_002015"
     CDS             complement(283..1167)
                     /gene="rsmA"
                     /locus_tag="LP468_002015"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL2081529.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            complement(1160..1729)
                     /gene="rnmV"
                     /locus_tag="LP468_002016"
     CDS             complement(1160..1729)
                     /gene="rnmV"
                     /locus_tag="LP468_002016"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL2081530.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            complement(1722..2498)
                     /locus_tag="LP468_002017"
     CDS             complement(1722..2498)
                     /locus_tag="LP468_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2081531.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            complement(2653..3975)
                     /locus_tag="LP468_002018"
     CDS             complement(2653..3975)
                     /locus_tag="LP468_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2081532.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            4150..4737
                     /locus_tag="LP468_002019"
     CDS             4150..4737
                     /locus_tag="LP468_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081533.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            complement(5216..7225)
                     /gene="metG"
                     /locus_tag="LP468_002020"
     CDS             complement(5216..7225)
                     /gene="metG"
                     /locus_tag="LP468_002020"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL2081534.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            7493..7771
                     /locus_tag="LP468_002021"
     CDS             7493..7771
                     /locus_tag="LP468_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081535.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            7868..8689
                     /locus_tag="LP468_002022"
     CDS             7868..8689
                     /locus_tag="LP468_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2081536.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8974..9984)
                     /locus_tag="LP468_002023"
     CDS             complement(8974..9984)
                     /locus_tag="LP468_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2081537.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(9996..10949)
                     /locus_tag="LP468_002024"
     CDS             complement(9996..10949)
                     /locus_tag="LP468_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2081538.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            complement(10939..12009)
                     /locus_tag="LP468_002025"
     CDS             complement(10939..12009)
                     /locus_tag="LP468_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081539.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            complement(12015..13058)
                     /locus_tag="LP468_002026"
     CDS             complement(12015..13058)
                     /locus_tag="LP468_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081540.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            complement(13059..14000)
                     /locus_tag="LP468_002027"
     CDS             complement(13059..14000)
                     /locus_tag="LP468_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081541.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            14084..14431
                     /locus_tag="LP468_002028"
     CDS             14084..14431
                     /locus_tag="LP468_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL2081542.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            complement(14501..16162)
                     /locus_tag="LP468_002029"
     CDS             complement(14501..16162)
                     /locus_tag="LP468_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2081543.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
BASE COUNT         4662 a         3382 c         2945 g         5471 t
ORIGIN      
        1 ttgtgtcaca tctccttgtt cggcataata gtggtcaaaa gcttgcatca agtaataaga
       61 ccaactaact caaaaacatg agaagctgtt ttttgaaatt gttccttgtg acttagagtt
      121 aaacggcagg cccacaacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat
      181 aagcccaaac aaacgaaaaa catgaggaac tatttttgtt tggctgttct tattacttga
      241 tgcaggacag ctttttcaca acttctgtca caacctcttt ttttactgca tattttctga
      301 catcgcattg cttaatgcgg cgaattcttg taatgacaaa gtctccccac gacgttttgg
      361 atcgattcca gctgtttcca agctttttgc taaccatgct tttgtctggt catctttgcc
      421 atacgaatgc tgcaagttat tccaaagcgt ttttcttctt tgctgaaatg ccgcttttgt
      481 caatcggaaa aatgcttttt cgtctgtcac ttcgactgcc ggtatatctc ttcttgtcag
      541 tttcaaaatc gctgaatcta catttggctg agggacaaat actgtttttg gtacgatgaa
      601 tgctaaactg gcttccatat aatattgaac agcaatcgat aatgaaccat aagctttcgt
      661 tcctggttca gcagagatac gatcagctac ttctttttgc atcatgacga ctagttcatc
      721 cacaaccaaa tctgattcaa gaaaatgcat catgatcggt gtcgtaatat agtaaggtaa
      781 attcgctacg acttttaacg gaagctcctc atgaaatgtt tctctaacag ctgttgacaa
      841 atcggtcttt aaaatatctt gatgtacaat agtcacattg tcatagggtt gcatcgtatc
      901 agccaataca gggatcaaac gatcatcgat ctcaaatgct acgacttgtt ttgcatgctt
      961 ggctaattgt tccgtcaatg caccgattcc tggtccaact tcgatcacgt tcgtatgttc
     1021 atctatttgc gcagtttcta cgattttcct taaaatattt ggttcagtca gaaaattttg
     1081 tcctaaactt tttttaaatg aaaaaccatg tttcaataaa atctcttttg ttctagaggg
     1141 tgtcgcaatt tcacgatatt cactcatgtt gttcctccac tattttcatt gcttgggcga
     1201 gttctttcgg cgtaatacga aacatcttca aacgtttttc caattgtttg ccgttcgtgt
     1261 aaccgatgcg caactcgtca cctagttttt ctcgtttttc ttttgcttgt gccccagcta
     1321 ttaaaccata gtctaaaagg tcttgtctag tgatttcaga aacagccgtt tgggaaatgt
     1381 ctggcgtcac gacctttttc aatgcttcta aaatagcagc atcacttgca tgctcgacac
     1441 caaggcttcc ctttttcttt ggtttagctt gtgtgcgcgg caaaaaagca tgttttgcct
     1501 gaggaacagc ttccataatg atttttctta ttttttctcc tgaaaaatca ggatcggtaa
     1561 aaacgatcac tccacgagtc tcttgggcat gttcaatttg catcaggatc tcttcattga
     1621 ttgcagaccc tattgtttct atcgtatctg catcaactac ttcccgcagc cttcttgtat
     1681 cgtcttttcc ttcaacgact ataatctctt ggatcttcat cttatccatg ttcgcttaga
     1741 ccaaataatc ggtgcgcatt tgtccatgtt tgggcagcca cttcttctgt cggaagattc
     1801 cgaagttcag caatcttttc tactgtataa cgagtatagc ctggttcatt tcgctttcct
     1861 ctaaaaggaa ctggtgccag ataaggggca tctgtttcca caagtaatcg ttcgattggt
     1921 acatttgctg cagcctcttg gacgtctaat gcttttttga aagtgacgac accgctaaat
     1981 gaaatatgca tccctaagtc aagaaatcgt tttgcccatt cataatcacc actgaaacta
     2041 tgcatgattc caccgatatc tcgaacatct tcttctttta ggatttgata cgtgtcttca
     2101 agtgcttctc tagtatgaat actgattggt aggttcattt cttttgcgat agcaatctgt
     2161 ctgcgaaata ctttatcttg gacttctttc gggtcttcca tccaatgata atccaagcca
     2221 atttccccta atgctacaac ctttggtaaa gtcaattgtt cttgtaattt attttcgatt
     2281 tctttcgtat aactgccagc ctctgtcgga tgccagccga taatactgta tatatttgga
     2341 tagtcatggc ttaattgcaa agacttttca atcgttggcg tatcgaagcc cacgaccgcc
     2401 attttcgtta cccccatttc ttgtgctcgc tgaatcgttt ctggaatatc ttcattgaac
     2461 tgttcagcat ttaaatgggt atgagaatca aatatcatgt ttatctctcc ttttcattct
     2521 tactttagca cataagcact acttgcagaa gtagcaaaaa tcaaaataga agaacttgtt
     2581 ttattgaaat agaaaaagca cgaagatcta gaggacctag ttcgtacttt ttctgtctgt
     2641 tgttgaaata ttttactctt ctgagcgttt tttctttttt tgataataga ctgggatacc
     2701 tatcaaggta acacctatac cgatcaatgc taatttcgtt tgcgtcatca tcgtcatacc
     2761 taaaatgaaa atagcaccga gaatcgcaat aatcggaacg attggataaa gtggtacttt
     2821 atatggacgt ggcaattccg gcgctttttt tcttaaaata aagacaccga taaaaatcag
     2881 taaactgaat agccacatca caaaaatcaa catgtctgtt aaaaagtcga aagaaccaag
     2941 gctcatcata atacaagcta ctgctaactg gaaaaccgca ggaacataag gaaccgtaaa
     3001 cttctttgaa agctttgtca gctgtttact gaaaggtagc tcgtcttcta aagccatcgc
     3061 ataaggcacg cggatcccag ttagtgtata accgttcaat gcaccgtata ccgagatcaa
     3121 gatcccaata gtgaccagct ttccaccgat tcctccaaaa atgacgtctg atgcttcaga
     3181 agctgcattc aaattaccgg caagatgatc aatcggcaaa gttttcaaaa aaacaaaatt
     3241 gatcaataga taaacgactg ttacaaaact caaaccaaga ataattgctt taggcaaatc
     3301 tttttccggc cgtttcattt cccctgccat tgcaccgaca cctaaccagc cgtcataagc
     3361 aaacaacgtt gctaacaacg cactgctcaa tccttcgaca aaagtaacat cttttccagc
     3421 ttcgattgga aataactgga cagttccttg tcctggggtc aataatcccc atatgacaat
     3481 cacagcaatt ggtattaatt taacaatcaa cgtcactgat tgtacagaag caccgacttt
     3541 tgtccctaac aaattcaacc ctgtcacaga aacagcggtg atcactgcaa tcaacaaaag
     3601 ataatcggta gataattgta ataagttcgt caattgtgtc gcaaagataa tcgataatgc
     3661 agcaatatta gcaggaaagt aaatcaagct ttgcgcccat cctaataaaa agctgggcaa
     3721 ttttccatac gcagcttcaa tatattttac agctccacca gtttccggga ttgctgtagc
     3781 taattcagcc actgtcaatc cagcacagat cgttaagaaa ccacccaaaa gccaagctag
     3841 caatgtcaaa cttgtagact gagtactagc agtaacagca gcagttttga agaagacgcc
     3901 tgcaccgatc acggttccca taacggtagc taatgcgcca aacagattga tttctcgttt
     3961 tagtttgcct ttcattccca tcctctttct tctttgaaat ttggtataat tttcagtata
     4021 actgagaata ttttaattta ccattctttt ttctccactt tcagtgaaaa actccctctt
     4081 aagacggatg tatttctttt ttatttttcg tatactaaac ctaccttttc cacgaaggag
     4141 gaacagttta tggattttaa gcgttcttat ccgaaattag cagattattt atccaaccgg
     4201 gtcgattttt cccgtaaaga acaacagcag tcccattggc attggttcac attaatttta
     4261 tttggattaa tgactgttgc aacgttatca caaaaactaa tattgctgac tttgttcatc
     4321 gcaatcgttg cattgatcaa aggtcctgtg atgatcttgt gggggatgtt gtattccttt
     4381 ttggttgggc tttttccgcc tatcggtatt ttgctttcag cgattttctt tttattgaat
     4441 atcggaacat ttacaaagaa ctggcggatg accttagtcg ggatctattt ttatttctat
     4501 ccttttggag tgatggcact tagtgaagtc atgcattggg ataatcattg gtttatagct
     4561 ggctccttgc ttttagggtt gatcttgtta cacgtgatgt tgacaaagct ctatcaacat
     4621 tatggtatcg gacgtacgat tttctggtat gtcttttcga tcccatttgc actgcttact
     4681 gctctcttac caagccgttt gaagacaaaa ataaaaggtt accataaaat caagtgatag
     4741 gatttttaca aaataaagaa aacaatcatc gaagtcaaag ccgatgattg tttttttatc
     4801 tatattttca atcacacata taagagcaca aactaattga acataaagtg atagaactta
     4861 taattaacac atcaacgcta ctgttagata taaatataga tgtaataaag tcattgcatt
     4921 caaactttat gaatgtaagg acaataaaaa agagtaccag atgaatcaat taaaatctgc
     4981 ccgacccttt atcattatgc tttttttctg tttttacgat tcctattagt attattctaa
     5041 attaacaaaa atcagcgaag ctcgtacttc tttttctagg atttattttg gatagttctc
     5101 tgtttctgta ttatatgatt ggcttcaagt aataagaagg aatttacgaa aattgcttct
     5161 caaatttcgg aaaaaggggg tatgacacaa ctagtgtcat accccctttg aatttctatg
     5221 cgatttctga gccatttggc atggattttg gtgcttcgat tacttgtaaa gagccatctg
     5281 gtgcttctgc agaaaggatc attccttgac tgatttgtcc acgcatcttt cgtggtttca
     5341 gatttgctac aatgacgact tttttcccga tcaattcgct tggatcagga taaaattcag
     5401 cgattcctga caagatttga cggtcttggc tgtctccagc atctagtcgg aattgcagca
     5461 acttatctgc cccttctact ttttgacagt tgatgacttc tgctactttt agttctactt
     5521 tttcaaatac atcaaatttg atttgttttt ctttcgttga aacaagttct gtttcttctg
     5581 gatcccattt gactgtatct tcgtttgttt gagtaccttc agacattttt tcttgaataa
     5641 aagcaacttc ttcttccata tctaaacgtg ggaagattgg tgtacctttt gcaactactt
     5701 ttgttcctga aggaaattcg ccaaagtgta atccttcaag attcattgtt tcagagtcca
     5761 atcctagttg attgaagatc ttctctggcg tttctgtcat gattggctga agtaatatcg
     5821 ctgcgatacg caaagattca gctaaatgga tcatgacact attcaattca gctttctttt
     5881 cttcgtcttt tgctaatacc catggttctg tttcatcaat gtatttgttt gcacgagaaa
     5941 tcagcaccca gatttcagcc aatgctgtat tgaattccat tttttccatt gcatcatggt
     6001 aacgtccgac aacgttagca gccgtcgtag acagttcact atcaaatgga gtgacaagtg
     6061 aggcatagtc aggaacgagt ccatcacaat atttgttgat catagcaatc gttcgattca
     6121 ataagttccc tagatcattt gccagatcat aattgacacg ggaaacaaaa tcttctggcg
     6181 taaagacacc atctgaccca aacggaacag cacgaagcaa ataataacgg agtgcatcta
     6241 aaccataacg ttccacaagc atttcaggat aaacgacatt tccttttgat ttagacattt
     6301 ttccgtcttt catcaatagc cagccatgcc caaatacttt tttaggtaga ggcaaatcaa
     6361 gggccatcag catgattggc caatagatcg tatgaaagcg aacgatttct ttaccgacca
     6421 tctgaacatc tgcaggccag tatttttcga atagactttc atcttcggag ccatatccta
     6481 gtgcagtaat ataattggat aatgcatcga tccatacata caccacatgt ttcggatcac
     6541 tcttgactgg tactccccaa gtaaaagttg ttcgtgaaac tgcaagatcc tctaatcctg
     6601 gtttgataaa gttgttgatc atttcgtttt tacgagattc tggctggatg aattcgggat
     6661 gttcttcata gtattccaat agacggtctg cgtatttgct catgcggaag aagtatgatt
     6721 cttcttttac caattctact tcgtgtccac ttggcgcttt accaccgatc acgttacctt
     6781 cgtcatcttt gtacacttct gcaagttgtg tttctgtaaa gaattcttcg tcagaaacag
     6841 agtaccagcc ttcatattca cctaagtaaa tatctccctg ttctaataaa cgatcaaata
     6901 ttttttgaac agctgcttta tggtaatcat ctgtcgtgcg aatgaattta tcataactga
     6961 tatcaagcgt tttccataat ttcttgacat cagccgccat tttatctaca tattcttgcg
     7021 gttttacacc tagttcttct gcttttgttt cgattttttg accatgttca tccactccag
     7081 tgagataaaa cacatcaaag cccatcaacc gtttataacg agcaattgcg tcacatgcaa
     7141 tcgtagtata cgagttgccg atatgaagtt tgccgcttgg ataatagatt ggcgtagtga
     7201 tataaaaagt ttccttttct gccacggggc tcttcctcct ttatcgcatg atgcgaattc
     7261 gtttccttgc tagtatacca taaaaaaagc atgctgttag ctttttttca aaatgaaaaa
     7321 gactggataa acgacttcta tctacgttca atctatcctt taaaaggatg aataggttga
     7381 ataaatgcgg gtttttgttt tgtttcatat ctactaaaaa acggcttttt atttctcccc
     7441 tcacacgtgg tataataaag actatctatc ttagtaaggg actggaacaa tcatgcagaa
     7501 gaaacatctt ttttttacac ttagtattgc ttttctttca ttagcacatt taatattcag
     7561 ctatttttat attcgtatgt atggttattt taacctccat gggcatttga acagttttat
     7621 gacagcagct tggattttgc gttttatcat tgacgtatat atcgttattt gtggcttctt
     7681 tgccattcgt gaagagcggt ataaagtatt gccgttttat ctgcttttct ttttattcaa
     7741 tctcatactt ccatttattt ttcatattta aatgataacc tagatttttc aagtaaatcc
     7801 ttggtttttt ttcagagtct gctacaataa ggtaaaaagt acttttactg tcaatggagg
     7861 tggtcagatg aaccgttttg cttctaaaga agaagaaaaa ttatattatg aacataaagc
     7921 aagtgaagaa gaatttctta actggtatca aaaacaggaa cgtccagaat atgacaagcc
     7981 ctctttgact gtcgatatcg tactgatgtg ctataacaaa gaagaagatc agctgaaagt
     8041 tttgttgatc caaagaaaag ggcatcctta tcgaaattca tgggcattgc ctggtggctt
     8101 tgtccaaaag gatgagtcaa ctggagaaag cgtcttaaga gaaacaaagg aagaaactgg
     8161 tgtggttatt tcaaaagaaa atattgagca actgcataca ttcagtacgc ctaatcgaga
     8221 tccgcgaggc tgggtcgtca cagtcagcta cttagccttt attggagaag aaccgctaat
     8281 cgccggagat gatgccaagg aagtacgctg gttcacacta gaacgtcata gtaacaagat
     8341 ccatttatct agcggagaag tggctatctc gcttgattta gtcactggag agtcttctgg
     8401 caaagatact ttggcttttg accatagtca aatcatcttg aaagcattca accgtgtagt
     8461 caataaaatg gaacacgagc cgcaagttct acaagtttta ggtaaagatt tcacgattac
     8521 ggaagctcga aaagtatttg ctaaattctt agggatcgat tataaaacga tcgatcattc
     8581 caattttaag aaagctatgc tccaatattt cgatgagatc ggtgaacgtc ctgtaggaat
     8641 cggccgtcct tcaaaaatct atcagctcaa gccggggcac catgaataag gttgtgagca
     8701 aaagattcag acctaatcat tcaagaaaaa acgcaaaaac aactctttgt gagttacgtt
     8761 ttttgtttca gaattttgat gtattcgtaa actttctgaa taaaaaatta acaatagcag
     8821 aaaaagctcg tacgaacttt ttctgctatt gttttattgg tttgtcataa ttagtgagct
     8881 tttcttcaaa agaaaaattc ctagaaacaa aagtcattaa gactttttat taacaaggct
     8941 aaccctaacg ctcctatcag tttcattcat tttttatccc ttgataaccg aatgtctgcc
     9001 cattttttct actacttggc tctttcttac ggaattgctt tcttctgctc cgtcggtatt
     9061 gatcaaaaga aattttttat tataccattg ggacttataa cgcaattttg ttattaattt
     9121 atgccagtcg tgaatagaaa aatcagcatg tgcctcttct tttggaaaag attctacaaa
     9181 taagtagtca tattgtttga ccaatttccc agataattgt tcaagataat cttctcgctg
     9241 gttcttttgt ttcagataaa gatccattac ttttctcttt tgtttctgat aattgcttgc
     9301 ctgatctaac ctgatctttc tatggtgagc ggagcggact ttcacattca atttccgctg
     9361 tgcatgttgc agcttttctt ctgtctggtg aaattttggt aaagttactt ctagaggtcg
     9421 agatgtttgg atcaatgtct tcggatgata ggcgatcccg atccatttag ctaaagattc
     9481 tttttttact ggcgaaacat cacaaagtag tgcgacataa aattcttcat tatatcgagc
     9541 agaaatcgta gcggagcgaa tcgatccttc aactggccga tgctgattta tcttgattag
     9601 ttctttttgt tttggtaact ttaagtagcc attttccaga tagatcgtac gggtttggtt
     9661 gttggtcgta taagattgcc acatactttt tttcgtttta agctttggga agctggcacg
     9721 tcccttgaaa taattgcgaa aagcccgatc caaattaagc tgtgcatttg ctaaagcaag
     9781 actgtctact tcttttaaga atgggtattc tttttttaat gtagcgggtg tgagcgaaaa
     9841 attggctact cctgtttgtt gccaactttt ctgccgcttt ttcagcaaat ggttataggt
     9901 aaatcgagca catccaaaag tacgaatcaa ttgctgtttt tgttcttctg tcggatacat
     9961 acggaattta aaagctttta gcatctatgt ccctcctagt tagcaaccag aagagattcc
    10021 ttttgtcgtt ttagtttttt tgcgtaatat gggacttcct gctcagttgc atagacaaaa
    10081 tgttctggtg cgatttcacg aagttgacgt acttgtccgt catctggttc aggttgatat
    10141 ttgattcttc tgcgttttct ctcatggtct ggatctggta gaggaatagc agataacaaa
    10201 ctttctgtat aaggatgaac accgtgatta tagatttcat cacttgttcc catctctaat
    10261 aacaagccgt tatgcattac accgattcgg tcactaatat gtttaaccat cgacaaatca
    10321 tgtgcaataa atagataggt caattgatgt tctttttgga gatcttgcaa caaattgacc
    10381 acttgggctt ggatcgacac atctagtgca gaaattggtt catcacaaat gataaaacgc
    10441 ggttttactg ccaatgctcg tgcaatacca atacgctggc gttgcccacc tgaaaattca
    10501 tgaggataac gagtaccgtg gcttggattc aatccaacag ttctcaatag atcatcgact
    10561 ttttttgcac gctcttcaga tgatttagct agtccattaa catcaattcc ttcggcaatg
    10621 atatctctga ctttcatacg aggattcaac gaagcgtatg gatcttgaaa gatcatctga
    10681 acatcatgcc ggaatttcgt caaacctttt ttatctttga tcttcgttat atcttgaccg
    10741 tcgaataata tctcaccatc agtaggttca ttcaagcgaa tgatcgtacg gccagtagtg
    10801 gattttccgc ttccagattc tccaactaaa ccgaatgttt ctccttcata aatgtgaaag
    10861 ctgatgtcat ttacagcatg tacttcattc ttttttccta cattgaaata ctgtttcaat
    10921 cctttaactt caagtagttt atttggcatc agcaattcct ccttgaccgt aagtatgttt
    10981 ttgtttctct ttaaagatag cccagcgacg ttggatttct tctggcggtg tcactttggg
    11041 tgcctgcgga gcaagtagcc aagttgctgc cttgtgtgtt tttgatagtt caaaaaatgg
    11101 tggttcttgt tctgcatcga ttttcatcgc gaattcattt cttggataga atgcgtctcc
    11161 ttttggcggg ttcaataaat ccggtggaga accaggaata gcatacaatc gatcgttcgc
    11221 actatctaat gtcggcattg aaccaagcag tccccaagta tagggatgtt gcgggttgta
    11281 gaaaatttct tccgatgttc caacttcaac gattcttcct ccatacatga cagcgacacg
    11341 atcagcgaca ttcgctacta caccaaggtc atgagtgata aagataattg atgtatcgat
    11401 ttttgtctga atttctttca gcagctccaa aatctgtgct tgaatagtca catcaagcgc
    11461 tgttgtaggt tcatcagcaa tcaggatttc cggataacat accagtgcaa tcgcgatcac
    11521 gatccgttga cgctgacctc ctgagaactg atgcggataa ctgttgatac gtttctcagc
    11581 ttcgggtatt ccaactaatt taagcaattc taatgcagct ttttgtccct ctttttttga
    11641 aactttatta tgctttctaa gggactcagc gacttgcttc ccaatgggca tcgtcggatc
    11701 taaagaggtc attggatctt ggaaaatcat cgctatttct ttaccacgga ttttttgcat
    11761 ctctctttct gattttccaa cgatatcgtt acctttaaag aggatttgac cagcatctat
    11821 attggcgttg cttgacagca agcgcatgat gcttctggtc gtcactgatt ttccacttcc
    11881 agattcccca acgatcgcca atgtttctcc tttattcaaa tgaaaattga caccgcgaat
    11941 cgctcgtacc tttccagcat acgtatcaaa agagatttct aagtctttca cttctaaaat
    12001 tttcgtcatc gtcttcactc tttcatttta ggatcaaagg catcacgcaa tccatcagca
    12061 agtaagttaa agccaatcat gataaccgat aaagttactg ccggaatcca taatagataa
    12121 ggcagataca ggaatgtctt gtacccttcg ctcaacatcg ttcctaatga agctgacgga
    12181 ggcgtaagac ctaaaccgat aaagcttaaa aaggcttcga agaaaatagc agatggaata
    12241 ctaaacatca tttgaataat aatgacacta gagatattcg gcaaaatatg tttgaatgca
    12301 attttcattc ttgattcacc taatgtcaat ccagctaaaa catattcttg atcttttaat
    12361 ttcattgttt gtgcacgaac gatacgtgcc attggtatcc agtttgtgat ggccatagca
    12421 gccacgattg aaaaaattcc tggttcaaaa acgaccaaca tcaaaatcat gacaacgagg
    12481 tttggaattc ctgataagat ttccaaaaaa cgttgcatca cgttatcgac acgtccgcct
    12541 aacaaaccag aaaccaaccc gtaagctaca ccaatcgtta catctagtaa tgcagcaata
    12601 aatgcgatca gcaacgagat tctcattccc ataaataagc ggcttaatac atcacgtccc
    12661 aaaccgtctg ttcctaaaaa gaaatttacg tttgaaggga cgtttgcttg agcatattta
    12721 tcaacaagtt caccaccaac cattgctttt ccattcaatc catcgatatt gattcccgga
    12781 atacgaggag gcaaattgat ataagccacg ttttgggcag ttggatcatg aggagaaaca
    12841 aagattgtga tcacagagat caaaatgatg accaatagta aaaccattga aataacggca
    12901 gctttgtttt tctttaaacg gcgccatgaa tcttggataa aattcaaaga aggtgcagta
    12961 atctgttcac gttcttcttc ggtatttttt tgtaatggaa gaaattcatc cgcagggata
    13021 tctgcaactg tttcataacg ctttggtatc atttccattt atcctcggct cccttctgaa
    13081 acacgaattc ttggatcaac tagaccgtac aatagatcca cgatcaaaat aacaaaaatc
    13141 agcataaatg agtaaaggat cgttacagcc atgatcgtag gataatcatt tgttgtgatt
    13201 gacttaacga attgttcccc gataccagga atagcaaaga tattttctac caccagtgat
    13261 ccggtcatca atgctacagc taacggtcct aataaagtca tcaatggaat caaactattt
    13321 cgaagaccat gtttaaaggc gatttcccaa cggctcaatc cttttgcttt tgctaattcc
    13381 acataatcac tatgcagtac ttccaccatt tccgtacgga taaaccgagc agagtcagca
    13441 agcggcgaca tggccaacgc aattgttggt aagattgtgt acacaaagcc atcccatttt
    13501 gcgattggca aaacttgtaa tttgattgca aagatatatt gtaataaaac agcaaataca
    13561 aagtttggaa tggaacgacc taatatcgct acgagtgtag aagatgtatc tgcccatgta
    13621 ttttgcttca tggcagagat cgttcctaaa atcgtcccta ggactgttcc aaagataatt
    13681 gcctgtaacc ctaactgcaa ggatggtccg attcttccag ctaacaaatg tgcgactggc
    13741 tggtttttaa attggaagga aattccaaaa tctccttgaa gcaaattaga aagataaatc
    13801 ccatattgta cgataactgg tttatccaaa ccgacttgtt tatttagcat ctcgattgtt
    13861 tcaggactca aacgttcctg attcgtatat ggcgtgcccg gcagcaattg catcaagaaa
    13921 aaggtgattg ttgcaattaa ccaaagcgtg atgatcatga aaaagacacg ttttaataca
    13981 tatttgatat aactattcac taatgtttcc ccctagcttt tgacttctga cagatgtttc
    14041 gctacattat tagataatga accaaaaata aaggagcaat caaatgaaaa aaaaatctat
    14101 cccctacgca gtagcttttc tactgattct ggttatttta ataaaaaatc tcatcaacca
    14161 ttcctttaca ctcattcaat tatctaatga tctattctta tggtcattgc cgtttctgat
    14221 tatcggcggt tttttatggg tcttttcttc gggtttcttc gatcattttc agcgatcggt
    14281 ccatcttgca cgaacaagga accgaaagaa aaaaccagaa ttttcctcgc tctcgtctgc
    14341 cagctacggt atgtacagct tttggctgat cattgccgga atactaattg ctctttctgc
    14401 tattttcatg cttttttctt tgttaggata agtgaatatg agaacgaggt tgcgacattt
    14461 gccgcagcct cgttttttct catgctcacg gtattaacga ttattcttca acgtatgtcc
    14521 atttgtaatc ccatgaagcg cctgccgcat ggtgaacgat acctttgatt ttttcattca
    14581 ctaggtgacc ttctgctttt tggtacaccg gaacgacacc catatcatca gagatgatct
    14641 tgattgcttt ttggaaatca tcccaacggg cttgttcatc gccagcgtct gttgatgaag
    14701 ctgctttaac tgcttcgtca tattctgcat tgctccagcg accacggttg tatgaattac
    14761 ctgtgacaaa caaatcagta aagctgcttg ggtctgcata gtcagcagcc catccgccta
    14821 gtactgcgtc aaaatcaccc gaagttgagc ggtcaagacg tacagagaat ggaacaggtg
    14881 ttggtttgac tgttacgcca tccaagtttt cttggattga gttttgaaca tattcgatta
    14941 cttttttcga tgaatcatca tcagaagcca tcaaatcaaa ttctaaagaa tcaacgccca
    15001 attctttttt cgctttttcc caatattctt ttgctttatc tttgtcataa gaaactaatt
    15061 ttccagcttc ttttgcaaag tcttcgttcg ttgttggact ttttaccata tctgatggga
    15121 tcaatcctgt agagacaact gatccgtcac ctagtacttg ttttactaaa gcttcacgat
    15181 cgatagaata agaaatagct tttcttaggt tcacattgtt gaatggtgaa ttcttttcac
    15241 gttgattgaa ttcgatatag cttgtccgcg cttctttaac agaagtataa gctggatcgt
    15301 ttgcgttttg ctgtgctaac tcaccagaca agatcacgtc atctgcttgg ccatctttga
    15361 ataagttcaa tgcagtagaa gattctttta ctacactgac tttgatttca gaaagtttta
    15421 ctgtatcttt gtcccagtaa tgatcatttt tcttataagt ccattctgta tctgttcctg
    15481 gtccatcaaa atcttctaat gtgaatggtc cattataaac agctttatca cttgcagatg
    15541 cataggcatc cccattttct tccactacgg attgtttttg tgggaaaaat gatgggaaag
    15601 caagcagata ttggaaatat ggtgtttgtt tcgtcaattt gatttctaat tcatagtcac
    15661 caactgcttt gatccctagt tctgatttat ctttctttcc agctgtaatg tcttctgcat
    15721 tttcaactgg cgcatacagg taagcatatt cagaagctgt agctgggtct actgttcgtt
    15781 gccagccata aacgtaatcc gctgctgtaa caggatcacc atttgaccat tttgcgtctt
    15841 ctcgtaattt gattttgtaa gttaatccgt cttcactgac ttctgccaac tcgctagctc
    15901 ctgccggctg tggtttgctg tcttcatcaa gacggtaaat tccttcataa acgttattca
    15961 atgctgtaaa actgattgta tctgttgcaa ctgataagtc agctgtaggc atttcttgag
    16021 gcacgactaa gttaaatacg cctcctccat ctgctgaacc gctttttgct gaactactgc
    16081 ttgtggctga actgccgcca taacatccag caagtacaag gccgcatacc gcaaccaaac
    16141 caaatgtaaa tttctttttc attttacgta cccctttatt ggaattttca gaataattaa
    16201 tattttctga agttgtttaa gagtttaatg aataattatt aaaaaatcaa cacttttttt
    16261 tgtctttttc ataaaataat gattttttcg tgaggtttca aggaattttt cagaaaaaat
    16321 agctttgtac aaggttttcc atggtcttcc aaaagccatt aaataatttt cgttatattg
    16381 tctattattg ccatacaaag ataaaaaaga ataaacaaaa agaaactgtg acaaaagtct
    16441 tgtcacagtc ccttatctga
//
LOCUS       DAFEML010000054        15853 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFEML010000054
VERSION     DAFEML010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.055"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            293..1432
                     /locus_tag="LP468_002030"
     CDS             293..1432
                     /locus_tag="LP468_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL2081544.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1499..2074)
                     /locus_tag="LP468_002031"
     CDS             complement(1499..2074)
                     /locus_tag="LP468_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2081545.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2079..3053)
                     /locus_tag="LP468_002032"
     CDS             complement(2079..3053)
                     /locus_tag="LP468_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBL2081546.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3077..3121)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3336..4304
                     /locus_tag="LP468_002033"
     CDS             3336..4304
                     /locus_tag="LP468_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2081547.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            4417..4695
                     /locus_tag="LP468_002034"
     CDS             4417..4695
                     /locus_tag="LP468_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2081548.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            4813..5049
                     /gene="secG"
                     /locus_tag="LP468_002035"
     CDS             4813..5049
                     /gene="secG"
                     /locus_tag="LP468_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL2081549.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            5152..5907
                     /locus_tag="LP468_002036"
     CDS             5152..5907
                     /locus_tag="LP468_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2081550.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5910..8267
                     /gene="rnr"
                     /locus_tag="LP468_002037"
     CDS             5910..8267
                     /gene="rnr"
                     /locus_tag="LP468_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL2081551.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8289..8753
                     /gene="smpB"
                     /locus_tag="LP468_002038"
     CDS             8289..8753
                     /gene="smpB"
                     /locus_tag="LP468_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL2081552.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9055..9774
                     /gene="atpB"
                     /locus_tag="LP468_002039"
     CDS             9055..9774
                     /gene="atpB"
                     /locus_tag="LP468_002039"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL2081553.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9827..10042
                     /gene="atpE"
                     /locus_tag="LP468_002040"
     CDS             9827..10042
                     /gene="atpE"
                     /locus_tag="LP468_002040"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL2081554.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            10133..10657
                     /gene="atpF"
                     /locus_tag="LP468_002041"
     CDS             10133..10657
                     /gene="atpF"
                     /locus_tag="LP468_002041"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL2081555.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10644..11186
                     /locus_tag="LP468_002042"
     CDS             10644..11186
                     /locus_tag="LP468_002042"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL2081556.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            11209..12765
                     /locus_tag="LP468_002043"
     CDS             11209..12765
                     /locus_tag="LP468_002043"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL2081557.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12779..13681
                     /locus_tag="LP468_002044"
     CDS             12779..13681
                     /locus_tag="LP468_002044"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL2081558.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13704..15110
                     /gene="atpD"
                     /locus_tag="LP468_002045"
     CDS             13704..15110
                     /gene="atpD"
                     /locus_tag="LP468_002045"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL2081559.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15124..15546
                     /locus_tag="LP468_002046"
     CDS             15124..15546
                     /locus_tag="LP468_002046"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL2081560.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         5264 a         2839 c         3419 g         4331 t
ORIGIN      
        1 ttttttttgc aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca
       61 tccttgaaaa aggaaagcta acaataacta gcatcatata agagctttta aggatagaac
      121 agtagaatag gaatctatga gcaagtcctc tcgtataaat aaaataggag ggaagtagca
      181 gcatattttt cataaagtgg ctctctttct tcatttttac tttggttgct cctatttgaa
      241 aattcgagca cactcaaata caataaaaag aaatggcaag ggagaggatt agatgaaaaa
      301 agaagaaaaa atcgcgattt tacaagagat catccgaatt aaatcagtga atggaaacga
      361 aggtgaagta gcagcctatt tgaataagct tttggcaaag catgacataa caggagagat
      421 tgtttcttac agagatggta gagataattt gattgctcgt taccaaaagg gccaatcagg
      481 aaaagtgtta ggcctatctg ggcatatgga tgtcgtggcg gctggtgatg aatcgtcttg
      541 gacctatgca ccctttgcag cagaaatcca tgggaaccgt ttgtacggac gtggtgctac
      601 agatatgaag agtggcttgg cagcaatggt gattgccatg atcgaactga aagagtcagg
      661 aaaaccattt aacggaacag tcaaattatt agccactgtc ggagaagaag tgggtgaact
      721 aggtggggaa cagctcacga aagcaggcta tgtagatgac ttagatgcct tgatcatcgg
      781 agagccaact aattacagtt tgatgtatac gcacatggga tcaatcaact atacagtcac
      841 ctcgcacgga aaagaagcgc atagctctat gccagaccaa ggttataatg caatcaatca
      901 cctaaatgaa ttcattacga aagcaaatgc tgaaatgaat cacctcgctg aaacaatcga
      961 gaatcctgtc ctaggaaaaa caatccataa tgttacattg atcagtggcg ggaatcaagt
     1021 caacagcatc ccaagccatg cgcagctcca agggaacatt cgatcgattc cagaataccc
     1081 aaatgataaa atcattgcat tgctgcaatc aatcgtcaat gaattgaatc aagagacaga
     1141 ctatcatttg gaattgatga tcgattacaa caaaatacct gtcaaagctg atccagattc
     1201 tcctttgatt cattgcattc agcaacaatt cagccagcca ttacctttag ttggagcggc
     1261 agcaacaacg gatgcagccg aatttacgaa agctaaccat tccttcgact ttgtcgtctt
     1321 tgggcctggt gtcgttactt tgcctcatca agtagatgag tatgttgaaa tcgataatta
     1381 tttggatatg attgaaaaat atcaaggaat tattttatcc tacttagcgt aagatttttt
     1441 taataaatga aaaaacagag ccagattagc attattttgc taatccagct ctgtttattc
     1501 agcctatttt tctttttgaa tatatcaagc gttgtggcaa catagtgatg actaatgaaa
     1561 caacgacgat agacaacaaa cgatcaaggt agtctgtacc tgcctgtacc aagatcacac
     1621 ttgttgtctg acttaaacct aacccatgta atagctgaac gatcatactg gatcctgagg
     1681 aggtgatccc gccaaataac tgaacggtaa tgatcgaaga aacgatcgtt ccaggtaccg
     1741 acaaaatcaa agcgagtaat aacagtttca agctgttttt atctttgccg agatatcttg
     1801 gcaaaatcaa tccagcaagc aagcctgtga gaatttggat tggcgaataa tacagagaaa
     1861 aaatatctgt agtcactcca cttaaaatac cgctggacaa tcctgtcagc attccaggta
     1921 caggcccaag caatgcacca gcaaaaatcg ttccgataga atcgagatag attggcaaac
     1981 gaagccataa agcaatcgtt cctccaatat aattgatccc aatacacaaa gccatcactg
     2041 taagtacgcg agttgccatt ttgtttttat tcattttgtt agcccatctt taacctttcc
     2101 aaatctttca taatcgtttc ttcttgtgca tttaaaagaa cggttaaaaa ctttcggaaa
     2161 aaaagacgag tatctacttt tgtcataatt ttactgttag caggtttctg ccaaaattca
     2221 taacgatcaa ccaatgtttg tccacgactt attccttgag tttccacagc agtgaagctt
     2281 ttgaaacctt cacagatggc cccctcgata aaataagcaa cagctaacgg atcattgatg
     2341 acacatccta aaattctttc ttgtttccag tggaagtcaa aataaaaacg agtgatcgct
     2401 tttagatact ctccctcttc aggattcatt tgacagcagt attcgaggat agtcggtgtc
     2461 aagacgattt ctcttgtcac atctaaccca accatttcta tcgtttgttt gagattctcg
     2521 aatacataag aagctgcttc aggatcacac cagtaattgt attcagcaac tggcgaacag
     2581 ttaccatggc ttttgtaagt tccacccatc gagacaaaac gatccatatg tttcccaata
     2641 tttgggttga ctttcaaagc aaaagcgata ttggtcaaag gacccaaagc aatgactgat
     2701 gtatttgtct tttctttgaa ataatcagcc aaaaaatcaa cggcatggag aggttctgcc
     2761 tgttttctca agatcatcgg gaaatttgtt tcccctaaac catccatacc atgagtgtct
     2821 tgtgcactga tgaaaggttg cttcaaaggt ttttccattc cttgataaac aggaatgtct
     2881 aaacgatcac agcgttccag gcatttcagc acattctgcg tacctatatc tgcagggaca
     2941 ttcccacaaa ctacggtaat agcaactact tcgatatcag gggatttgac agctaatgat
     3001 aaagctaaag tgtcgtcgat ccctggatcg caatcaataa ttacttttcg cattatttcc
     3061 aatctccttt ctttagagat acttagtttt ttattctggg aagtttccga accagtccaa
     3121 gacgagcgtc ttgattataa tgcacgaaat tagtatactg gcttttattg cgaatgtaaa
     3181 tgctctctta caagtaaatc tattgaggag aactttaagt aaatgataca atgaaaaaga
     3241 aatggaattt acgtgtgccg aaaataaaga atcctatgga tcggtacatt ggataatagt
     3301 tagattatag tttggcagaa agcggcgggt gtacaatggt tattttttat ttcattctta
     3361 ttctgataat tatagggatc agttaccatt ttctttctta tttttatgca aagaaattag
     3421 taagagcggg agtacagaga ggatatgact ggtatgaaga cactggtcat cgtttgatgg
     3481 accctgctgc agtcacgtca gtagaaaaaa aacgacaaaa attagaagaa gagtgtgaaa
     3541 gcttttggga gcagggaaca cccaaaacaa tcaaaagtta tgacgggttg aaactagctg
     3601 gtcagatgtt catccatcca aataagcaga ataaatgggt catttgcgta catgattacc
     3661 gaagcacagg gaaaagagac atgtctcata taggtaaaag atatgcagag aaaggattca
     3721 acgttcttgt acctgattta cgtgcgcacg gagaaagtga aggagaaatc atcggaatgg
     3781 gatggctaga tcggctagat ttaattgcct ggatccaact catcttagat gaacagccga
     3841 atgcgtccat tattttacac ggcggatcaa tgggagcttc tacgatcatg atggcaagtg
     3901 gtgaaaaact tccatcagcg gtcaaaggat ttattttaga cagcggatat gtttctgttt
     3961 atgcagaatt ccgatatatg ttaagtaaaa tcactgtctt tcctaaaaaa atggtcatga
     4021 gatatgcgaa tcattatgcc cagaaatacg ccggttactc cttaaagcaa gcatcagcta
     4081 cgagacagct tggcagcaac catctgcctt tattggtcat tcatggtgaa agagatcatt
     4141 ttgtccctac agaagcagcg tacacgattc aaaatgctac ggcaggggat aaagcactgc
     4201 tgcttgttcc agaagcagaa cacttggaag catcgatgaa agatccgaaa acctattgga
     4261 cagtgatttt ttcatttatt gaacaaagaa taacgatgaa ttaattttct cttctttttt
     4321 gtaagtaatt cgaggataaa taattgttta tagatcagga gactgctaaa ataaggtagg
     4381 aataaaaaaa tatcagttat ttgaggagtg cggcatatgg aaatcaaaga agaaaaaaat
     4441 cgtcttgctt tattcaatga tgaacaacaa gagatcggag aaatgacatg gtcagatgcg
     4501 ggcccagaca tcatgatcat tgaccataca tttgtagatc cagcatatcg tggtcaaaag
     4561 ttagctgaaa agctagtgta tactggagta gaattagcaa gacgagacgg gaaaaagatc
     4621 attcctttat gcccttatgc aaaaaaagag tttgaaaaga aaccagaata tcaagacgtc
     4681 ttacgtcagt cataagaata acagctgaaa gttttgaact ttcagctgtt attccattta
     4741 tatagagttg tcatggactt ttatctatga taaagttaaa gagacgatat cttttgggaa
     4801 ggaggctgcg atatgtataa tttaattttg ggaatcgtga tcgttttatc gattgttatg
     4861 gtcattgcga ttatgatgca gccaagcaag caaaatagtg cagcgagtgc atttaccggc
     4921 ggtgcggatc aactattcgg caaacaaaaa gctcgcggct ttgaagctgt catgcagcga
     4981 tcaactgcag ttatgggagc tatctggatg atcttattat ttgtcctagc atatttatct
     5041 tcgaagtagt tgaataagcc tctcgcaaaa cggcgggcgg ctttttttat tgcaaagaga
     5101 acgcttaaga agaagttatg aaagaaacta tggtaaaatg aggcgaaaga ggtgagacga
     5161 gtgagacaat taccaaaacc cctttatgca aaacatggaa agcgagcggt tttgctgctt
     5221 cacgcttact caggaagtcc aaacgatgtt cgaatgctcg cacgattttt ggaaaaagca
     5281 gattatacag tttatgcgcc gctttttaaa ggacacggaa caatggagcc atatgatatt
     5341 ttgcaagaaa aagcagaaag ctggtgggca gacactaaaa aagccatcca ttttttacag
     5401 tctgagcagt tttctgatat tgccgtatta ggattatcaa tgggcggcat ctttgctgta
     5461 cgagcactag aagaagaatc agtgattggc ggcggttttt tctgttcgcc tttgtctcct
     5521 gtaaaaacaa acgtgcctga aaactttgaa aaatacgtac gtcaagtgct gaagacagca
     5581 ggtaaatcag agaaagaaat caatgaaaaa gcagttgctt accgctcgtt agctgaacaa
     5641 caattaatgg atatacaaga tcaggcagca atcgtagaaa gtaggttgtc agatatccaa
     5701 cagccgatat ttttagctca agctgggaaa gatgaaatga tcgaccctaa tggcgtattt
     5761 gaaactgcac gcaagttgag ccgtcagcga gtgacacttc gatggtatcc tgaaagtggt
     5821 catgtgatta cagttggtac agcaagacgc gaattagaaa aagacgtctt ggaattttta
     5881 gaaaaattac cttggaatga ggaataaata tgacaaaaga aacgataaaa gagaaaattc
     5941 tctttttcat ggaaagcagt cgcaaacgca gtttttctat ggaagaaatc gctgaaggtt
     6001 tagggttcca aaaaagcgat gattttaaat tactagtaca aacgattgct caaatggaaa
     6061 gagaacagag tatagttttc aataaaaaag gaaaagtgaa acttccttta aaaccaatct
     6121 tgatcgaagg aacatttcga gcaaatgaac gaggatttgg atttgtaacg attgatcccg
     6181 aagaagatga catctatatc ccaaaagaag cgactggttt tgcaatggat ggagacaccg
     6241 tagcaatcga tatcatgaag cgagcaaata cagatatgga tcgcggagca gaggggaaag
     6301 tagtcgagat tcgagaccgg gcgactactc agttagcagg ggaattcgtt gcttattcag
     6361 aagaagaaat acaagaaacg gatctttacg gcgttgttat cccgaaagat agaaagctca
     6421 accaatttaa agtatatgca gcagcagagg gagttcgtcc agttgacgga agtattgtgc
     6481 tgatcgaact gacccattac cctgaaaaag ggtatgcgac tagtttagaa gggataatca
     6541 agcaagtgat tggtcataag aatgaccctg gcatggatat cctctcaatt gtcgtggcta
     6601 atggtatccc tacgaaattt cctgatgatg tattgtctga agcagatgaa gttccagatc
     6661 aaatcagcga aaaggatata actggacgta gagatttaag aaatcagctc attgttacga
     6721 ttgatggaga agatgcaaaa gatctagatg atgcagttac ggttaaaaaa ttagataacg
     6781 gtaattattt tcttggagta cacattgcag atgtttctta ctatgtgaca caaggcagtc
     6841 aattggacag agaagcatat gaaagaggga caagtgtata tttgactgat cgagtgattc
     6901 cgatgatccc gcaacgttta tcgaatggta tctgttcact gaatccccat gttccaaggc
     6961 tgaccatgag ttgcgaaatg gagattgatc caaatggaca agtagtctct catgatattt
     7021 tcccaagtgt gatccaaaca acagaacgga tgacctacac agctgtcaat caaatcttag
     7081 aagatcaaga cgaagaaacg atgcaacgct atgctcagct cgtacctatg ttccaagaaa
     7141 tgggtgaatt gcatcgaatc cttgaaacga tgcgaatcaa acgtggcgcg atttcttttg
     7201 aggatcgcga agcaaaaatc cttgttgatg ctgaaggaca cccaaatgat atccagctaa
     7261 gaagcagagg aattggtgaa cgcttgatcg aatctttcat gcttgcggcc aatgaaacgg
     7321 tagctgaaca ttataataaa ttaaatctgc cgtttattta ccgaatccat gaacagccaa
     7381 aagaagaaaa aatgcagcgc ttctttgatt ttgcttcagc tttgggcatt ctggtccgag
     7441 gaacgaaagg aacgatcaca ccaaaagatt tacagcatgt gatcgaagga gtagaagaca
     7501 aaccagaagc tgcagttatc aatactatgt tgctaagaag catgcaacaa gcacgctatt
     7561 cagaagacaa ttttgggcat tatggcttag cggcagatta ctacacacac tttacatctc
     7621 ctattcgacg ctatcccgat ctaatcgtcc atcgtctgat ccgttcttac agtgaagata
     7681 aaagtgaaag caatcaaagt tcgtgggcta cggaacttcc tgaaattgca gatcatagtt
     7741 ctaagatgga acgtcgtgca gtagaaacag aacgtgaagt agattccatg aagaaagcag
     7801 aattcatgat ggacaaagtg ggggaagaat tcgatgggat catcagctct gttgtgaaat
     7861 tcggcctgtt tatcgaactg ccgaatacag tagagggatt gatccatatc aatgaattga
     7921 aacaggacta cttccatttt gttgaaaatc atttagctct tgtaggtgaa agaactggtc
     7981 tgacttttaa aatcggacag aaagtgcgag taaaagtagt caaagctgat ccagatgaac
     8041 gagcagtaga ttttgaactt gtttccgcag aagaggttac agcgttggaa cggccaaaaa
     8101 cacgaaatgg aaaatcagga aaacgcgaag gaaaacaagc aggaaaacgc ccagaaagaa
     8161 atggcaagaa gaacaaacga tatagcgata gtaagcaaac gttcggtaag aaaaaaggga
     8221 agaagccatt ttacaaaggt gttaaaaaga agaaaaagaa aaaataaaat gagttggagg
     8281 aaacagctat gccaaaaggc gagggaaaat taattgcaca aaacaagaaa gctcgccatg
     8341 attattcgat catcgacacg atggaagcag ggatggtctt gcaaggaacc gagatcaagt
     8401 cgatacgaaa cagccggatc aatctaaaag atggatttat tcgcgtccgc aacggagaag
     8461 ctttcttgca taatgttcat atcagtcctt atgaacaagg aaatattttt aatcatgatc
     8521 cgttgcgcac gagaaagtta ttattacaca aaaaacaaat catccggctt gaaaatgaat
     8581 tgaaaaatac tggaatcact gttgttcctt taaaagtcta tattcgtaac ggctatgcca
     8641 aggtattgat tggtctggcg aaagggaaaa aatcttatga taaacgggaa gatttgaaac
     8701 gaaaagatat cgatcgacaa attgatcgaa cattaaaaaa tttctctaga taatttcatt
     8761 atcctttttc gcatattcgg tgcttttgct tttacttaat gataaaattt gttagcattt
     8821 aatctgataa aacatgatta tcataggttt tttcttagat caggagcacc gtgtataaag
     8881 aaaaattcgc ttcgtttttg actgaaataa aaaagtgtct aattttcatg aaaatgtttt
     8941 gaattttctg tttcatggtg gtatgatacc gtgtggttag aaaccgattg gaaaaaacca
     9001 gatacgcaca tgaattgatt ttatgtgaat ttcggggaaa agaggtgaaa tggattggat
     9061 gaacgctcgc taacgttcca cattggacca atttggtttg atggtacagt ttgtataatg
     9121 gtgttactga cctgtttgat tgttttcttc ttagcttact tttttacaag aaatcttaag
     9181 ttgaaaccaa caggcaaaca aaatgcgata gaatgggtca ttgattttag tcgaggaatc
     9241 gtaacagata atctgcctag aaaagaattg agcaatttcc atttgttggc atttacattg
     9301 tttttatttg tttttgttgc aaacaacatc ggtttagtaa caaaaatcgt tttacctaac
     9361 gaaacaacac tttggaaaag cccgacagca gacccgtttg ttactttaac tttggcattt
     9421 ataatgatct tacttactca cttatttggg gtgaaaaagt taggcttcaa aggatatttc
     9481 gtaaattcgt tcttgaaacc atatagtttt atgtttccga tgaaactgat tgaagaattt
     9541 acaaacttat taacacttgc tttacgtctt tatgggaata tttatgcggg ggaagttttg
     9601 ctaaccttga ttgcaaaaat ggtaataagc ttaggctggt tctcattgcc gttagcaatt
     9661 ccattagaga tggtctggat cgcattctcc ttgtttatcg gaagcatcca agcatttgtc
     9721 ttcgttactt tatctatggt ttatatgagc cataagattg aagtggaaga ataatattcg
     9781 ttttaaaaac aaactactat ttatctaatt taggaggaaa acaattatga attatatcgc
     9841 agcagcaatc gcaatcatgg gagcagcaat cggagccggt tatggtaacg gtcaagttat
     9901 ctctaaaaca atcgaatcaa tggctcgcca acctgaaatg tctggtcaat tccgtacaac
     9961 aatgtttatc ggggtagctc tagtcgaagc tgttcctatc ttaggggtag ttgtcgcctt
    10021 gattctagtt tttggtgttt aattgaatca gtattaaggc agaaacaatt tggtttgtta
    10081 ctgctttttt acatgaaaac tagaagtact tcaaagaaag gaaggctcgc ctatgctgaa
    10141 tcaattggca attgcagaag ttggcaatgc gatgttagga aatgtcatcg ttgtcagcgg
    10201 ctcatttttg atactactgg ctctcttgaa gcattttgct tggggaccaa tcagcgatat
    10261 tttgaaaaaa cgtgaagaca agatcgccaa tgatttggat tctgcagaac aatctcgcat
    10321 caactcagcg aaaatggaac aagaacgcga acaacaattg ttagcctctc gttctgatgc
    10381 agctgatatc atcaaaaatg cgaaagaaag tggagaatta agccgccaaa atattttgaa
    10441 ggatgctcaa gaagaagcag ctcgtctaaa aagtaaagcc caagctgata tcactgtaga
    10501 acgtgattca gcgctgaact ctgtaaaaga cgatgttgca gaactatctc ttcaaatcgc
    10561 ggaaaaaatc ttgaacaaag aattatctcc agaaatgcac gaatcattaa tcaatcaata
    10621 tatcgaaggt ctaggttctt caaatgaaac tagataaata tacagtagga agacgttacg
    10681 ggaaagcttt atttgaactg gcgatcgatt caaataaagc agaagaaatt tatcaagatc
    10741 tcgtaagctt acgtcaaatc tatgaacaag tacctggatt aggtaatatg ttaagtgatg
    10801 ttcgtctaga acctcatgaa aaacgagaaa tcatggacaa gcttgttagt ggctatgatg
    10861 gaatcgttaa aaacttttta gaagttgttt atgcgtataa ccgaatggat gatcttttgt
    10921 tcatgatcga agaatatgaa cgtcgatatg atgaacatca aggtttgctg ttgggaagtg
    10981 tcacaacagc agttccactt tcagacgaac aacgaataca attagaaaag aatgttgcaa
    11041 aaacaatgaa ctatcaatca gtcgaattaa aacaaatcgt tgattcttct attattggtg
    11101 gcgcgattgt tgaagctaac catcgagtaa tcgacggaag cattcgcacg caattagaaa
    11161 atatgcgtaa tcaattaaat agatagtaca aagaggtagg tgaatcgaat ggccatcaaa
    11221 gcagaagaaa ttagtgcctt gattaaagaa caaattgaaa attatcaaaa cgtgctttca
    11281 gtcgaagaaa tcggtaccgt aacttatgta ggtgacggga tcgctcgtgc acatggttta
    11341 gaaaacgcga tgagtggtga gttgcttgaa ttttcaaatg gctcatacgg aatggcgcaa
    11401 aacttagaat caaatgatgt aggtatcatt atccttggcg atttcgagtc cattcgtgaa
    11461 ggagataaag taaaacgaac aggaaagatc atggaagttc cagttggaga ggccttgatt
    11521 ggacgggtag ttaatccgct aggtcagcca attgacggac taggtgaaat cgttactgac
    11581 aaagctcgtc cagtagaagc aatggcacca ggcgttatgc aacgtaaatc tgttaacgaa
    11641 ccaatgcaaa caggtctaaa agcaatcgac gctcttgtac caatcggacg cggccaacgt
    11701 gaattagtta tcggtgaccg taaaacaggg aaaacttcca ttgcgatcga tacgatcatc
    11761 aaccaaaaag gtcaagatat gatctgtatc tatgtagcaa tcggacaaaa agattctaca
    11821 gttcgtacac aagttgaaac attgaaaaaa tatggcgcaa tggattacac aatcgttgtg
    11881 aatgccggtg cgtctcaacc agcgccgttg ctttatatcg caccatatgc tggtactgca
    11941 atgggtgaag agttcatgta caacgggaaa catgtcttga tcatttttga tgatctttca
    12001 aaacaagctg ttgcttatcg tgaactttcc ttgctgcttc gccgtccacc aggtcgtgaa
    12061 gcttatccag gggatgtttt ctacttacac tcacgcttat tggaacgtgc agcaaaatta
    12121 agtgatgatt taggtggcgg ttcaatgact gccttaccat ttgttgaaac acaagctgga
    12181 gatatctctg cttatatccc aacaaacgtt atttcgatca ctgatggaca aatcttctta
    12241 gaaagcgact tgttctacgc aggtactcgt ccagcggttg atgccggact atctgtatct
    12301 cgtgtagggg gttctgcgca aatcaaagca atgaaaaaag ttgctgggac tttacgtcta
    12361 gacttagcaa gttaccgtga attagaagca tttacacaat tcggttctga cttggatgca
    12421 gcaacacaag caaaactaaa tcgtggacgc cgtacagtag aaatcttgaa acaaaaattg
    12481 catgcaccgc tagctgttga aaaacaagta gtgattttgt atgctttgac acatggattc
    12541 ttagatagta tccctgtaga cagtatttta gacttcgaac atgaattatt cgaatatctg
    12601 gataccaatc attcagatat ctttgaaaca atccgtacaa caaaagatct tccagaagaa
    12661 gaagcgttga acagtgcgat tcaggaatat aaagacatgt tcttagctac aaaaggaaat
    12721 aattcctcta cagaagataa attgaaatcc attcaaaatg catagtgagg tgagatgaat
    12781 gggtgcttca ttaaatgaaa tcaagacacg tatcgcttca acgaaaaaaa cgagccaaat
    12841 cacgcgggca atgcagatgg tgtctgcttc taagttgaca aaatctgaag cttcttcaca
    12901 gaagtttcag gtttatgcaa caaaagtaag agaaatcgtt acgcatttga ctgctactca
    12961 gttaaatgat attgcctcag aaaatcctag aggggatatc aattacaaca gcatgttgct
    13021 cagccgtcct gttaagaaaa cgggttatat cgtcatcact gcagatggcg gtttagtcgg
    13081 tggatataac agctcgatat tgaaacaaac gatgtctatt ttagaagaag accaccaatc
    13141 acccgatgat tacgtgatga tcgcaattgg cggaactggt gcagacttct ttaaagcacg
    13201 cggtatcaat ctagcatatg agctgcgcaa tctatctgat cagccaagct ttgatgaagt
    13261 ccgcaaaatc gtaaatatgg caacaactat gtaccaaaac gaagtattcg atgaattata
    13321 cgtatgttat aaccatcata tcaattcgct aactagtcag tttcgtgtag aaaaaatgct
    13381 gccaatctca gacttagatc cagaagaagc aactactttc gaacaagaat atatttttga
    13441 accttcaaaa gaagaaatct tgtctcagtt attgcctcag tatgctgaaa gtttgatcta
    13501 cggtgcgatc gttgacgcca aaacagcaga acatgctgct ggtatgacag caatgaaaac
    13561 agcaactgat aatgctgcta atatcattga tgagctgacg gtttcttaca accgtgcaag
    13621 acaaggggct attacccaag aaattaccga aattgttgcc ggagcttcgg cactagaata
    13681 gtattgagat tggaggaaaa aagatgagtt caggcaagat tgttcaagta atcggtcccg
    13741 ttgtcgacgt ggaattttct ttagaccaat ccttaccaga tatcaacaac gcattagttg
    13801 tttataaaaa tgacgaaaat aaatcaaaag ttgttcttga agcagcgtta gaattagggg
    13861 acggagtgat ccggaccatt gcgatggaat caacagatgg tttacaaaga ggaatggaag
    13921 tcattgatac aggcaaagca atctctgttc ctgtaggtaa agaaacatta ggtcgcgtat
    13981 tcaacgtact aggagatacg atcgatttag aaacaccttt cccagaagat gcggaaagaa
    14041 gcgaaattca taaaaaagca ccagcctttg acgaattaag tacaagtaca gaaattttgg
    14101 aaacagggat caaagttatc gatttgcttg ccccatattt aaaaggtggg aaagtcggac
    14161 tattcggtgg tgccggtgtt ggtaaaaccg tactgatcca agaactgatc cataatatcg
    14221 cccaagaaca tggtggtatt tctgtattta ccggtgtagg tgaacgtact cgtgaaggta
    14281 atgacttgta ttatgaaatg aaagattcag gagttatcga aaaaacagcc atggtgttcg
    14341 gacaaatgaa cgaaccacca ggtgcacgta tgcgtgttgc tttgactggt ttgacgattg
    14401 cggaatattt ccgtgatgta gaaggtcaag atgtactgtt gtttatcgac aacattttcc
    14461 gtttcactca agctggatct gaagtatcag ccttgttagg acggatgcct tctgcggttg
    14521 gttatcaacc aacattggca acagaaatgg gtcaattgca agaacgtatc acatctacga
    14581 aaaaaggttc gatcacatcg atccaagcaa tctatgtgcc agccgatgac tacactgacc
    14641 cggcgccggc aacagcattc gcccatttgg atgcgacaac caacttggaa cgtaaattaa
    14701 cagaacaagg gatttatcca gcggtagatc cattggcttc ttcttcaagt gctttagcac
    14761 ctgaaatcgt gggagaagaa cattataaag tagcaacaga agtccaacac gtattgcaac
    14821 gatatcgtga attacaagat atcattgcta tcttaggtat ggatgaatta tccgatcaag
    14881 aaaaagtgtt agtttctcgt gcccgcagag tccaattctt cttgtcacaa aactttaacg
    14941 tggctgaaca atttactggt cttccaggtt catatgtccc tgtagaagaa acagtgaaag
    15001 gattccgcga aatcttggaa ggcaaatacg atgatcttcc tgaagaagct ttccgaagtg
    15061 ttggccgaat cgaagacgtc gtagaaaaag cgaaaacact aggctactag aaaggggtgc
    15121 cccatggatc aatatttaac agtaaatgtg gtaactcctg ccggtttggt ctatgatcac
    15181 catgcagcta tcgtcgttgc acgtacgaca gctggtgagc ttgggatttt gcctaaacat
    15241 gcaccaatca tcgttccatt gacgattgat gaagttcgtg taaaacgaac agattcagat
    15301 acccacgtcg attggatcgc tgttaatggc ggaatcatgg aagttcgtga taatgttgtt
    15361 tcaatcgttg ctgatagtgc ggaacgtgaa cgtgatatcg atgtatctcg tgcggaacgt
    15421 gcaaaacaac gcgcagaacg ccaaatcgaa gaagcaaaag caaaacaaga tacgaacgaa
    15481 ttgaaacggg caactgttgc gttgcaccga gcaatcaatc gtatcaaagt atctaagcac
    15541 tcataaaatg agatgcggat gtttatccgt gtttaagaac agtaaaaaga ggttatgaca
    15601 gaagtggtca gcttcaagac ataagaagga atttacgaaa attgcttctc aaatttttgt
    15661 gaaatctcag cttatttttc gaagaagcta cttctggaac accgtatatc ggaggttgtg
    15721 aaatcagcgt tttgtcctga gtattagaga aacaaatgga aaatagttcc tcatattttg
    15781 ccgttttttg agctaatacc gagggtcaga tgattgaaca ccgtttattt ggaataaggg
    15841 actgcgacaa gac
//
LOCUS       DAFEML010000055        15457 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFEML010000055
VERSION     DAFEML010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.056"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(149..451)
                     /locus_tag="LP468_002047"
     CDS             complement(149..451)
                     /locus_tag="LP468_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081561.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(671..1037)
                     /gene="ssrA"
                     /locus_tag="LP468_002048"
     tmRNA           complement(671..1037)
                     /gene="ssrA"
                     /locus_tag="LP468_002048"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1208..1981)
                     /locus_tag="LP468_002049"
     CDS             complement(1208..1981)
                     /locus_tag="LP468_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2081562.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2125..2475
                     /locus_tag="LP468_002050"
     CDS             2125..2475
                     /locus_tag="LP468_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2081563.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2456..3172
                     /locus_tag="LP468_002051"
     CDS             2456..3172
                     /locus_tag="LP468_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081564.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3172..4620
                     /locus_tag="LP468_002052"
     CDS             3172..4620
                     /locus_tag="LP468_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2081565.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4691..5200)
                     /locus_tag="LP468_002053"
     CDS             complement(4691..5200)
                     /locus_tag="LP468_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081566.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5190..5915)
                     /locus_tag="LP468_002054"
     CDS             complement(5190..5915)
                     /locus_tag="LP468_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081567.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6138..8258)
                     /locus_tag="LP468_002055"
     CDS             complement(6138..8258)
                     /locus_tag="LP468_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2081568.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8488..9666
                     /locus_tag="LP468_002056"
     CDS             8488..9666
                     /locus_tag="LP468_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL2081569.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9682..10440
                     /gene="aroD"
                     /locus_tag="LP468_002057"
     CDS             9682..10440
                     /gene="aroD"
                     /locus_tag="LP468_002057"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL2081570.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10463..10948
                     /gene="ybaK"
                     /locus_tag="LP468_002058"
     CDS             10463..10948
                     /gene="ybaK"
                     /locus_tag="LP468_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL2081571.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11019..12272)
                     /locus_tag="LP468_002059"
     CDS             complement(11019..12272)
                     /locus_tag="LP468_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2081572.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12389..13738
                     /gene="gdhA"
                     /locus_tag="LP468_002060"
     CDS             12389..13738
                     /gene="gdhA"
                     /locus_tag="LP468_002060"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL2081573.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13850..15196
                     /locus_tag="LP468_002061"
     CDS             13850..15196
                     /locus_tag="LP468_002061"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL2081574.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         5082 a         2743 c         3121 g         4511 t
ORIGIN      
        1 tagtgactta tttttgattt tatagcactg atactataaa atatagatat catcatatta
       61 cacaatctta atactaactt aaaaaatatc ccttttataa gtatggtgat aaaatccgtt
      121 ccgggctacc ttttttaggt agcctacttt aatctttata cctttctgga tcaacgaaag
      181 tatacttcaa atagtcataa cgccgatgat cgctccgtgc gtctggcaca tcagtcacga
      241 tatcaaacaa aaaatacaca tctttcttca ttctggtttt tgttgccgga attttaaagt
      301 agttcttatt agagtaatag agattgatta ataagctatc ttcgattgct aaaaagaaaa
      361 cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga tcaaatttaa
      421 accataattg tgtttttcct tccatcaaca taatgttcac ctcaaaaaga gtatacgaac
      481 taatgttctt tttgtaaagt aggaatatca ttgataatat ggatggaaca tatatattaa
      541 aaagtgttct ttttgaatgc tattttgaat gccattttca ttcatttaac gaaaatctgc
      601 gaaaataaaa aatgctcaaa cccttataaa ataaggattt aagcatctag cgaaatctgc
      661 tgaaatctca caatggagac ggcgggagtc gaacccgcgt ccaaacacat cgccacttaa
      721 aaatctacgt tcatagtcaa ctcatttaag gattcacttt acagcttgcc gagtgacagg
      781 cattctgtat cgctagtctg atgttctctt tttcaactta cagacggaaa gttgaaacgt
      841 atcccactaa agttaggacc cttactcgag cacatgggcg atgccgagag gatctacgct
      901 aactgttttt aggcagctaa agcgtaagag ttgttttcgt ttttagcagt tatatttaac
      961 tgtaacgttt ttacgtagac gtaacctacg aaacgcaatt caagctcgac tgtgcctgtc
     1021 gaatccgtaa cgtccccgtt agctaacaag ggttacgtgt atttttcata caaaattagt
     1081 atagcatata ttgggataaa ttcaataaaa aagcgaatca tatcccatta tttatataat
     1141 aactgcccct ttcttaagaa aaaataagcg attttcttaa gaaaagaggt agcttcaaaa
     1201 aaagatctta aatcagatca aaatacttca atgcgtggac aattccgcct tctgtatttt
     1261 tctttgtgat aaaggtagaa agttctttta atccgtcata ggcgttgccc atagcgattt
     1321 tgttgtcgca agcttccaac aaggcaaaat cattcggacc atcgccaaat ccaaaagtag
     1381 gaactttttc cagctgaagt tctttttgca gacgtttgac acctgcccct tttgagattc
     1441 ctttcttcac tgtatcgatc gagtaaggac cattccgata aaaagttagc tcaggaaaat
     1501 gttcgtgata gtattcgtca cctgattgag ataagatcag caacatattt actgtgtttt
     1561 ctttaaagcc taaaggatca atttccggaa catctgaatg aatgaagtcg taagcattga
     1621 tcattgtttg gctatgaccg gtacaccaga ttttctgatc gttatagtaa gaaagttcat
     1681 gaccgttcaa ctgtacatga tcatacattt tttgacattc ttctgaagaa aatgtttgag
     1741 aatagatttc ttcgccgtct actcgaatga aagaaccatt catggtgacc gcagaagtaa
     1801 tgcccgcatc ttccatgata gagtggattt ctgcttctgt acgtcctgta gcgatgacgg
     1861 ggagaacatt gttttctttt aatgcgttca tagcttttgc cacttcgggt gtgatttttg
     1921 atttcgcatc tagtaatgtt ccatcaagat caaagaaagt gattgcacga taatttgaca
     1981 caaataaaac tcctttttta ttggaataag tttatcttaa caaagaatga acaaaagaca
     2041 aacctttcgt gaagaattcc tgaacatatt ggttcagtca acaatttaga gtatactata
     2101 agaagagaat ttaggaggga aagaatgatt tttttcagta ttggtatctt attcttaata
     2161 attggcagtc tttttcggat tctgccctca aaaggaaatc tgccttttta tgggtatcat
     2221 tcgcctcttg ccgcaaaaac agacgctcat tggcggctgg ctcaaaagac aagcggaaac
     2281 tggttttttc ttatgggctt actgatggca ttgatcggct attatttaaa gacatctggg
     2341 catacgaatt attttctgat tgaaatgctt ctgctagtat ttccaattat gcctattttt
     2401 attatgacag aaaagaaatt acagaaatat gacctggaaa ctggagggaa cgataatgaa
     2461 tattttaatg attgaagata atcaatctgt ttctgaaatg atgcagatgt ttttcttaaa
     2521 tgaaggttgg gaagcaactt tcaagtatga tggaaaagaa gggctcgatg cctttttaga
     2581 aaacccacaa cattgggata tgattacact agacctgaat ttgcccacac tggacggtat
     2641 gctagtagga agagagatcc gcaaagtttc aagtactgtg ccgattatca tgctgacagc
     2701 tagagattct gaaagcgatc aggtgatcgg cttagagatg ggggcagatg attatgtcac
     2761 aaaacctttc agtcctctga cgcttattgc tcgaatgaaa gctttgcatc gccgtagtga
     2821 gttggcagaa gcaagagaag aagcagtagt ttcagatgat cattttgata tcgagactag
     2881 tcatttcaag atgaatacga aaacacgaga agcgtatctg gacaaccggc caattgaagg
     2941 actgacgcct aaagagttcg atctattgtt tactttagca aaaaaaccac gtcaagtatt
     3001 ctctcgggag cagttgcttg aattagtctg ggattatcag tactttggtg atgaacggac
     3061 agtggacgcc catatcaaga aattacgaca aaaaatcgaa aaggtcggac cacaagtcat
     3121 ccaaactgtt tggggagtcg gctacaaatt cgatgattct ggtgttgcct aatgcgttat
     3181 ttgtatcagc aactcttagc tttctgcgga atggtcgcgt tgatcttatt gatcgttgga
     3241 gtttctttta cacaactgac aaaacaaacg attgaagaaa acaattacca gcaactgttt
     3301 ggatatgctg aatcagttga aaagacaacg caaacctatg ccgatacgct cccgcagttt
     3361 agtcaagatc aggcgtttca aaatgcattg ctgctgacag agcaagtact gacagaacaa
     3421 aatgtgaact ttatatttat cgataaaaac gaacgtgtca tttatccgac taatacagct
     3481 ttactgaatt ttaccttaac agctgatcaa tggaaaaatc tgaggaatgg acgtcaagaa
     3541 aaattcacat cgaataaaaa tattttagga caagcacagg cgacctctta cgcacttgtg
     3601 ccatttaatt tgaatcatga attctatgga gcacttgtag ttagtcaacc tgcgcgaaat
     3661 atcgataaca gcgttcgtcc aattacactg aacctgttca aaggatttat tttttccagt
     3721 atcgttgcag ttattgccag ctatgctttt gcagcattcc aagttaagcg tatcaatcgg
     3781 ttaaggaatg cgacgaaaga agtgacgaat ggtaattttg atgtacagct ccccgtacat
     3841 gacaaagatg aatttgatga gttagcagat gatttcaata aaatgacgaa ttcattgaaa
     3901 gaatctcaag cagaaattga agaacaagaa aatcgtcgaa gacaatttat ggcagatgct
     3961 tctcacgaga tgagaacacc tcttacgaca atcaacggac ttctggaagg gttagaatac
     4021 aatgcaatcc ctgaaaatca gcgagaaaac gcgattaaat tgatgaaaaa tgaaacagag
     4081 cgtctgatcc gtttggtgaa tgaaaacttg gattatgaaa aaatccgtac gaatcaaatc
     4141 agtatggtca ttaaaaaatt caatggaaca gaaacattga aaaatattgt tgcacagtta
     4201 gaagctaaag cagaagcagc aggagataca ttgacattga aagccgttga tgatattgat
     4261 gtttacgctg attatgaccg atttgtccaa atcatggtca atattattca aaacgcgata
     4321 cagtttactg aaaacggcca aatcacgatt actttagaaa aaggctatct tgaaacgatc
     4381 atcacgattg aagatacggg aattggaatg tctgaacaac aaatgaaaag tatctgggat
     4441 cgttattata aagtagatcc ttcaagaaaa aatacaaaat atggtgaatc aggattaggt
     4501 ttaccaatcg tgcagcaact tgtacgcttg cataaaggaa aattagaagt agaaagcgaa
     4561 ctaggaaaag gaacaaaatt cgctgttcgt ttgcctgacg tagaaatcaa aaaagagtaa
     4621 aaaacaagcg gtataaaaga tcatgaatcg atcttctata ccgcttgttt tttactataa
     4681 aatgattgat ttagcccgcg ggctctaaac gatcaatata aggactttga gcaatagtag
     4741 catcatgagt aaagagtaag ataccttgat tttcttcatg agctaaataa gaaagcaagt
     4801 ggagtagctc ttggatctcc aatacactaa gttcatcaaa tgtatcttca ataacaatat
     4861 tgtttcgctt ggaaagcaag gcatgaagta attgcagctt tactttttca aaagacgtca
     4921 actcagctgc cgcacaatta agcaaggaag gagagatatc aagtttttct tgataggcca
     4981 aacgatcttg tttgatttct ttttccggta catccaacag gacatggtct ttaagattca
     5041 gataaggaaa catcggccaa tttttttgga tgatcgcaaa attatccagt tttgcaacaa
     5101 gaacctcttt tttcaagtgc tccaatattt tatgctgttt ttcgagagga cacaaaataa
     5161 cggtcaagtg ttcagcatga atcaaatatt caggtttcat tacgtccagg cctcctactt
     5221 tgcaaatgat ggataaaaaa agtgaaaggg aatagactaa gaatgagaca gcatccactg
     5281 agcccaataa gagtttgggc aaatccctta agtatatctg tgaaaaaaag atcattttgg
     5341 aaatcgatgg taaaaaaagt ctgttgatcc atcggaattg taagtccgct taccgaagtc
     5401 aagatatcac ggatatctgg cagttcagta gtctttaaga caagaaaatt gatcctttga
     5461 agaagcgctt cataaactga ctggaagctt acgatccaca ataaaaccaa gatacaacaa
     5521 agaaagagag gaaagaacag ctgccagaaa ataaaaagga ataatttggt tttagaaaga
     5581 ccagtcaggt gccaattgat caattcctgc ttgttttgcc tgactgaata gtaaaagaaa
     5641 aagataaaaa ggaaggcaaa tagaaaaaat aaactgaata tgccttttat ataaaatcgg
     5701 ctagctaatt ctaaagccgg aagaagctct gtagatgcag aagcgccaat aaatgaaagc
     5761 cgatcttgga cttgattggc taaagccgat tgcaaatggt aaagagtcag gcatgctatc
     5821 aataaaaaag cagaaaagct tgaaaataaa caatagagta ttgtctgctt tttgtaataa
     5881 attaatcgag cagtagcata gcggattatt ttcatacttt tcacctctat aaaaagtata
     5941 gaaaatgaat atgaataaag tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa
     6001 aatattttgt aaaaagcaag aggttgtgaa gaagctgccc tattctatta ccgtagatgc
     6061 aagcttttga acactgttta ttcgaaaaga ggagcagcga caataatttt gtcgctgctc
     6121 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
     6181 gtttgcgttt tataaagatc aacagttgat tgtccgttgt gttcactaaa gacactagtt
     6241 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
     6301 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
     6361 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
     6421 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
     6481 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
     6541 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
     6601 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
     6661 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
     6721 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
     6781 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
     6841 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
     6901 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
     6961 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
     7021 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     7081 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     7141 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     7201 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     7261 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     7321 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     7381 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt catgctggag accattctca
     7441 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     7501 ttttttcctc tagcgagccc gaacaaatcg tcatttggtg ctgcataatg ttcttttaca
     7561 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     7621 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     7681 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     7741 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     7801 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     7861 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     7921 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     7981 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     8041 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     8101 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     8161 aaataggcaa aaatcgtttt caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc
     8221 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     8281 cttaatcaca gaagtgtcct gaaaccatgt tacacagctc acttattctc atttatttta
     8341 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     8401 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     8461 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     8521 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     8581 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     8641 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     8701 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     8761 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     8821 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     8881 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcatagg aggctatgag
     8941 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     9001 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     9061 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     9121 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     9181 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     9241 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     9301 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     9361 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     9421 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     9481 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     9541 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     9601 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     9661 cattagaagg agcgatgcag aatggttcgg gtaaagggat tgaatatagg aagcggtaga
     9721 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     9781 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     9841 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     9901 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     9961 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
    10021 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
    10081 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
    10141 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
    10201 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
    10261 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggttggc
    10321 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
    10381 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
    10441 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
    10501 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
    10561 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcgta tatttaaaac
    10621 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
    10681 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
    10741 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
    10801 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
    10861 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
    10921 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
    10981 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
    11041 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
    11101 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
    11161 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
    11221 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
    11281 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
    11341 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
    11401 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
    11461 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
    11521 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
    11581 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
    11641 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
    11701 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
    11761 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
    11821 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
    11881 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
    11941 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
    12001 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
    12061 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
    12121 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
    12181 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
    12241 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
    12301 tctgaagaaa gaaaacagaa aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
    12361 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
    12421 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
    12481 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
    12541 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
    12601 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
    12661 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
    12721 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
    12781 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
    12841 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
    12901 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
    12961 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
    13021 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
    13081 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
    13141 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
    13201 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
    13261 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
    13321 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
    13381 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
    13441 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
    13501 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgtccagcg
    13561 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
    13621 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
    13681 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
    13741 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
    13801 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
    13861 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
    13921 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
    13981 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
    14041 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
    14101 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
    14161 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
    14221 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
    14281 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
    14341 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
    14401 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
    14461 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
    14521 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
    14581 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
    14641 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
    14701 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
    14761 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
    14821 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
    14881 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
    14941 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
    15001 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
    15061 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
    15121 caagaaaaac atgttcgcac ttctaggcaa accaggcttt gaagatcttg ctaaagaatt
    15181 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
    15241 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
    15301 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
    15361 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
    15421 ggttaattct gtttttttgt tttctagaat cagtaag
//
LOCUS       DAFEML010000056        15373 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFEML010000056
VERSION     DAFEML010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.057"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..561)
                     /locus_tag="LP468_002062"
     CDS             complement(<1..561)
                     /locus_tag="LP468_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBL2081575.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(748..1398)
                     /locus_tag="LP468_002063"
     CDS             complement(748..1398)
                     /locus_tag="LP468_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081576.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1941..2876)
                     /gene="whiA"
                     /locus_tag="LP468_002064"
     CDS             complement(1941..2876)
                     /gene="whiA"
                     /locus_tag="LP468_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL2081577.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2910..3908)
                     /locus_tag="LP468_002065"
     CDS             complement(2910..3908)
                     /locus_tag="LP468_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL2081578.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3905..4789)
                     /gene="rapZ"
                     /locus_tag="LP468_002066"
     CDS             complement(3905..4789)
                     /gene="rapZ"
                     /locus_tag="LP468_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL2081579.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4924..5655)
                     /locus_tag="LP468_002067"
     CDS             complement(4924..5655)
                     /locus_tag="LP468_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL2081580.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5659..6924)
                     /locus_tag="LP468_002068"
     CDS             complement(5659..6924)
                     /locus_tag="LP468_002068"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL2081581.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7187..10003)
                     /gene="uvrA"
                     /locus_tag="LP468_002069"
     CDS             complement(7187..10003)
                     /gene="uvrA"
                     /locus_tag="LP468_002069"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL2081582.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10013..12007)
                     /gene="uvrB"
                     /locus_tag="LP468_002070"
     CDS             complement(10013..12007)
                     /gene="uvrB"
                     /locus_tag="LP468_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL2081583.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12266..13768
                     /locus_tag="LP468_002071"
     CDS             12266..13768
                     /locus_tag="LP468_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL2081584.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13770..14507
                     /locus_tag="LP468_002072"
     CDS             13770..14507
                     /locus_tag="LP468_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2081585.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14552..14725)
                     /locus_tag="LP468_002073"
     CDS             complement(14552..14725)
                     /locus_tag="LP468_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081586.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            14701..15366
                     /locus_tag="LP468_002074"
     CDS             14701..15366
                     /locus_tag="LP468_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081587.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
BASE COUNT         4527 a         3292 c         2595 g         4959 t
ORIGIN      
        1 tataaacatc accccaaata aaacagaaaa cagtataagc attataaaaa ttatcaacaa
       61 ccttgatcct tcttttatag attcaggaaa cagtataatt ttagtactag ataaattgtt
      121 tacaccgatt agtgttaaaa tatctttatt cttcttgcta acataaccct ttatgcacaa
      181 aagaacagct atacttaaag taacaaataa ataacgtatt ccaatagaaa aatcactata
      241 aatactctct agcataggac cgacaattga agaagtcact actgcaaatg ctggacctat
      301 ccaagcaaca ttagaatgtt ctttctctct tttcctttgt aaatctttgt tgagtattaa
      361 tctatttatt tcttctgcag gcaagttaat tttcataacc ttatggggga ttatccaatt
      421 aaaaatcgga aaaaggtagc ctccccaaaa agtatagtga tctgtgtcaa tcagataata
      481 acctgatttt gattccagaa taacatatct caaagccgaa cgaaaatttt tcatgaatat
      541 ccataatctc actgtttcca cacctaattc ctccaattcc aattaaatgg atttatagca
      601 tcaccaatta tgttaactgc ctgaccaacc tcattgataa aattggcacc actatcccat
      661 gcttcaacaa tgctatatat ctatcaaaca aaaaatggaa aactaaatac tcgcgcacat
      721 aaattttaca ttctgttttt tataagacta ataataatca ttgaaaaaat ttcttatcgg
      781 tggcgcatat tcccaattga ttaatgtgat cccatattct gcaagtattt tacgagcttc
      841 ttctaagtca tagtgagaaa aatgcataaa acctgcaata cgatcacgga ctgtgagctg
      901 tggcttgctt ccaccatcat tcataaaata tccagcagag ccactactta aagtgattgt
      961 tacatcttca ctttctatta ttaagaattc ataatgaaat gctttcaact ctccactatt
     1021 atttaaaagt tttatactcc aacttcgtct aggttgagtt gtcacattcc ctctaaaact
     1081 tcctataaat tctgcaatca ccgtatcttc aatcaaaatt ctttcctcat ctatttcata
     1141 ttcaagacta aacggaaatt ctccatatgt aatctctggc aatggtggtg ctgtagttct
     1201 ccaaataaat acaataactg tgaatagaaa aaatccaacg atcgatataa atgttatgag
     1261 acctgctcga agtaaaaccc gatataataa aaatgctgta tttcgctttg ctatatctag
     1321 aaaaataaaa agtactgcaa tcataatgat agtaaaagtt gtaaaaaagc acattttttg
     1381 ccctcccttt ataaacatcg attctcaaat tctaaaccaa atcttgatag ttcaagttca
     1441 ggtataacgt ataccaacca tacatcccaa ttactattta tgaacttatg attatcactg
     1501 aataaatcac tccatcccct tgttaaaact tctacattaa ttacacctgg ttgttttcga
     1561 ctagctaatc caatgaactt atcaaccatc cttatccacc aaccacgaga atcttgacca
     1621 gaagtaagaa aaacagttct caaggttgat cgagcagttc cttccagttt ttaattaatc
     1681 tccagttata gataaatact tgatcctatc tatatcagga cttctatatt aagcaaaagt
     1741 ttatgtataa aactaaaatc ttcattcagt tgtctccccg ctttttatac gattgtatta
     1801 aaaaacaata gaagcctttc aacattatgt tactccagta aagttggaat tatagtttga
     1861 cggaagaaaa gcaagtatag cttttaaaaa aaactgatac attcgcatct cctgcttcat
     1921 gtatcagttt tttctttgga ttaaactgct tcttcacgca gtttttccgc aaattcattt
     1981 attttgcgaa ttcggtgatt aattcccgat tttgatattg cacctgaggg aatcatttcc
     2041 cctaattctt tcaagctgac ctctggatgt tgaagccgaa gttctgcgat ttcctgaagt
     2101 ttttcaggaa gggcatgtag accgaccttt gcttcgatca attcgatgtt ttcgatttgt
     2161 ttagaagccg catcaatcgt cttgttcaga tttgctgtct cacaattgac tagacgattg
     2221 accgaatttc tcatatcccg tacgattcga acatcttcaa atcggagcat tgagttggtt
     2281 gcaccaatca atgttaagaa atcagcaatt ttttctgctc cttttaaata cgaaatatag
     2341 ccattgcgcc gttcaagcgt tcgagcatgt agaccgtaat aatttaacat atcgcaaatg
     2401 tcttggttat gctgttcata aatagaaaat atttccaaat gataacgact cgtttccgga
     2461 ttattgactg aacctgaggc cataaaagca ccacgtaagt aagaacgcat tttttgcgaa
     2521 tttcccataa tctcgtccga aacgtgtcca ttgaacatca taccatccat gatatcaaga
     2581 tccatcaaca catcttttgt gccttgcttc aaccggacga tatagacatt gttctttttt
     2641 aatttcattt ttttacgaac gagtagctca cttcgtacct gataatgatc tttcaaaaga
     2701 gaatagatac gtctggcaat tgcagcattt tctgtttgga cgttcaaaat aaactgctgg
     2761 ttcacaatac ctaaagagcc gttcattcgc agcaaagcag ctaattccgc tttcgcatgt
     2821 tctcgatgaa cttccaaacc agttagttct ttcttcacat ctgcagcaaa tgacatccta
     2881 ttctcctcct ttctccaaca ataaattgct taatattttg aaccgaaaac taaacggaac
     2941 aattcttcta ctactttgtc tccatcgtgg aagacaccac catctttcaa ttctaaaaag
     3001 tcggtggaaa tcactcgaca tccttcattt ctcaatccgt tgaagtcgtg tgcgacttgt
     3061 actagatact catcatagat ctctgggtcc atataatctt caggcacttt ttccgtattg
     3121 accaatactg tatcgataaa aggctgattc aaatgcttgt gtaaaacacg tatatgatcg
     3181 gcatctgtga aatgttccgt ttcccctttt tgggtcatga tattacagat atagacggtt
     3241 tcagcagttg tcttgagcat tgcttcgccg atttctggta tcactaaatt tggaaggata
     3301 ctggtgaata aacttccggg tcccaaaacg accatgtcgg cgtccataat tgctgaaacg
     3361 acttttcgag ccgctttggc ttcactttta tcatttgtgt tgcagacata cacacggtca
     3421 atggttttac ggttgatcgc gattttagat tctcctactg cagtcgttcc gtctttaaaa
     3481 acagcatgca aggtcaaagg agtttctgaa gaaggataaa catgtccatc tacatgcatc
     3541 atttttgcta ataattgaat cgcctcataa gtgcttcccc gcatctcgga aactgcggca
     3601 atgatcagat taccgatcgt atgattggct aaaaactgat cttccttttt gaaacggtat
     3661 tggaaaatat cttcatagaa ttgtggcata tccgataacg ccactaagac atttctcaag
     3721 tcaccaggag gagccatagc gatcgattct ctgattgcac cgctgcttcc accatcatct
     3781 gcaacagtca ctactgctgt gatatctgct ccttgatttc gtaaactttt caggataact
     3841 ggcagaccag tgccaccgcc gaccactacg atctttggtt ttcttatccg gtaggttttc
     3901 attttcacga ccggttcacc gtctctttcc ttttatcctt gtcccgatgt gtcacattga
     3961 ctttatagtt tttccctaaa gcatttgcca aacgttcagt caatgccaca gaacggtgtt
     4021 gaccgcctgt acagccgatt gcaactgtca agctgctttt tccttcttta atgtatccag
     4081 gcaatacagt ttccagaaga tccaaaaatt tatggtagaa tgattgcgtt tcatcaaagg
     4141 acatcacata atcatagact ggctgatctt ttccggtcaa tggtcttagt tccgggatat
     4201 aatgagggtt gggcaaaaaa cgcacatcca tcacaatatc cgaatcgatc ggcaacccgt
     4261 atttaaaacc aaatgataca aattcgatcc gaaatccttg gtctcccttt gatttgaatg
     4321 actcattgat tttttcacgt aattgtcgtg gtgtcaatgt tgtcgtatca atgatcacgg
     4381 aagcttgggc tttcaagtcg tctagtatcg cccgttcttt acgtatccct tcagtgatca
     4441 aaccgtccat cgccattgga tgtgctcgtc ttgtttcttt gtagcgagcc actagttctt
     4501 cgtctgaagc atctaaaaat aagatagaag tgtcgatgaa gttcgtattt tcgatttcga
     4561 tcagcatgtt ttggatttct tcaaagaagg aacgagaacg caaatccact cctaaagcca
     4621 tttttgtgac tttacctgat tctttgatca attcccagaa ttttggaatc aatcgaggcg
     4681 gcatattatc gatacaaaaa tagcccatat cttcaaaact ttggatagct actgttttcc
     4741 ctgcaccact catacctgtt atgatgacta attgcaaatt atctgtcata tttacgaacc
     4801 cctctcacat tgtgcataat aaaattatat catcccgggc gtatcattac cagttttctt
     4861 tttcttttac aaaaagattt ggaccaaata tcttttagga tatttgcccc aaatccaatt
     4921 tttttacttt tccgatgctg tatccaatgc ctcgcttctt tcagctaatg cacgttcgat
     4981 cgttcgatcc gctaaaatag attgagcatc gatcactggg taatgattat cttcagcaaa
     5041 ttcatgcatc aaagataatt ctgtgcaacc taggatgact ttttcacagt ttaggcgctc
     5101 taccgcttcc tctaagattt cgtaatagag ctcttgattc aaataatccg attccttgat
     5161 ctcatgatag atcaggtaat tgattttttc ttgaagcgca gtatcaggaa tcactgtttc
     5221 gaaaccaaga tttttgactt cgcgttcata gattccagct ttcatacttc cttctgttcc
     5281 tagaatcgct actctccctg tcgtatgctg acggacaagt tcatttgctg cttctcttgg
     5341 catatgcaag ataggaatat ccgttgccgc ttgtaactct tcaaaaaagt agtgtgcggt
     5401 gttacaagtc aacacaatga agtttggtcg caataaattt tgtttctcaa tatcatccag
     5461 cagaaacggc attggatttt cttctgatcg atctaaaata taagctgtac gatcaggaac
     5521 tgttgcatga ttgaataaga cataattcaa atattcttga tcttttgtag ctttcgttcg
     5581 gtggttgatc aagcgaacaa aactttctgt cgccatcgtg cccattccgc ctaaaatact
     5641 gaaaaaattc tccatgaact agccttcttt cacatgaaaa tactttttga atcttggaat
     5701 atagttatgg aacatatatt tcatcaacaa ccagcgcttg attgatcggt ctttttcata
     5761 aaatacagta gtaccgtaac gattttcttt gatcatttgc tcagctagtt ttttgtcttc
     5821 attttcccga gcatattcta aaaagatttt tttgggcaca cccatccata atcttgcttt
     5881 atctgattga ttcgttccat aggtcgtttc aacaaagggt ttgttgaaca ctcgatcttc
     5941 tgtgacaaaa cgagccagat tcaagccgtt caatgtcaca aagaaactgc tacgaccttg
     6001 tctcaaattg atttcaaata atttatattc tccatctcta ggatcatact tcatatcgaa
     6061 attggcaaag cctgtatatt cgattttttc caaaaatgcc ttaatggttt gatagatttt
     6121 ttcgttataa tctggcatga tcacaacgta attaccaatc gatgctggtg taggatcttc
     6181 taatagtgga tgaccaaggc acatcatccg aacttgatga tcttcatcta catacgcatt
     6241 tagcacacgc atattactat catcacccgg gataaaatct tgtacaatca tttcactttt
     6301 ataaccggct tcgtatatcc ggcctaaaat taaatcgaac tcttctctag tctctaaaat
     6361 aaaagctttt tttcttcctt caaattggac agaaagatac tccacactgt ttgcaggttt
     6421 caaagcaact gggaattcaa aaggcaattc ctgttccaaa tgtccattta ctaacatttc
     6481 ttctctgacg atcaatgttt taggatacgg aagatcatat tcttcacaaa cttcataaaa
     6541 gcttacttta ttgatcagcc tttcaaataa agaataatca atatatggac agataaaata
     6601 ttctgacagc tcttgtttat gttgggagat caattctgca tatccatcac cacaagcaat
     6661 caaaagatat tttttactct tatcagaata tctttctttt gccaaacgaa gcatcgtctc
     6721 gataaataca gggtctttat caaatcctgg aataacttct acattgacaa ttttactgta
     6781 gcgggtaggg gctaactgat ccgaagcata tgcttggcag attttgccgt atgcttcatt
     6841 aaaagaacgt gccataccat aaacgttcat gtcgcttcct aataatatag ggataaattc
     6901 ttcattttca atactgttca tcattatctc tcacttactc ataatctctt gtttttcttt
     6961 tccaactaca caaggaatat cataccataa agaaaaaagc aatcaaagga aagtcctccg
     7021 attgctcaat tcttttttga acggattgaa cttataggaa gtttttatct ataccaatca
     7081 gtgtagaaag aactaccatg taatgattct agaacactga tattaataaa acaagcaaaa
     7141 attcattttt ttatgttttt ttaactatct cagctatcta tcctctttat accattattt
     7201 ttttcaaata gtgacctgta taactttctt ttacgttaat gatttcttct ggtgttccag
     7261 tcgcaaggat cgttcctcca ccttctccac cttctggtcc taaatcaatg atataatctg
     7321 ctgttttgat tacatctaga ttgtgttcaa tcactaaaac tgtgttacca gcatctacta
     7381 atctttgtaa tacatgcaac aagcgggcga tgtcatcgct atgaagtcct gtcgttggtt
     7441 catctagtat atagaaattc tttccattag agattttgtg caattcactg gcaagtttca
     7501 tccgttgtgc ctcaccaccg gacaatgtcg ttgctggttg ccccatcgtc acataaccta
     7561 agccaacatc aacaatcgtt tgcagtttgc gatgaatctt tggaatgtgc ttgaagaatt
     7621 ctacagcatc ctctactgtc atttccaaaa tatcagcaat gctttttcct ttgtaatgca
     7681 cttctaatgt ttcagaatta tatcgtttac catgacatac ttcacaagga acatagacat
     7741 caggcaaaaa gtgcatttcg atcttaataa ttccatcccc gcgacaagct tcacaacgac
     7801 cgccttttac gttgaaacta aaacgccctt tcttataacc ccgcattttt gcctcgttcg
     7861 tttgagcaaa taacccacgg atatcatcaa atacacttgt ataagtcgct ggattacttc
     7921 tcggcgtccg gccgattggg ctttgatcga tatcgatgat cttttcgata ctttcgtagc
     7981 cggaaattgt cttgaattta cctggcttag cagaattctt atttaatttt tgcgctaacg
     8041 atttctttaa gatactattg accaatgtac tctttccaga accagacaca cctgtgactg
     8101 ctacaaattc tcctaatgga aattcaacac taatattttt cagattgttt tctgaagcac
     8161 cagtgatctt gattgctttc ccattacctt tacggcgttc ttttggtaca gggattgatt
     8221 ttttccctga aagatatttc cctgtcaaag aattttcatc attagctact tcttcaggag
     8281 tgcctgcagc cacgatttgt ccgccttgtt ctccggcccc aggtccgacg tcaatcaaat
     8341 aatctgctgc ccacatcgta tcttcatcat gttcgactac aacgagggtg ttgccaagat
     8401 cacgcatttt ctttaatgag ccaatcagtc gatcgttgtc gcgttgatgc aatccgatcg
     8461 atggttcatc taaaatatac aaaactccag aaagattcga tccaatttgt gtagccaatc
     8521 tgattcgctg cgcttctccc ccagataatg ttccggaagc gcgactcaaa gttagatagt
     8581 ctagtcccac attttccaag aatgaaagtc tgtcatttac ttcttttaaa atcggtttgg
     8641 caattacttt ctcttgttca gataacgtta agtttgagaa gaaatctact gctttttgaa
     8701 tagacaactc atttgtttgc ccgatattcg ttccattgat ttgaacagat agagcttggg
     8761 gattcaatcg ataaccttta catgtctgac aagttaattc tgtcatataa agacgcattt
     8821 gctcacgcgt gaaatcactg ttcgtatcat gataacgacg ctcgatattc ttcaataccc
     8881 cttcgaaagt cgtttctaca tcgcgaacgc caccaaaatc attttcataa tggaaatgga
     8941 aaagatcatc tgtcccattc aagatgatct cctgatgctc ttccggtaat tcttcgaatg
     9001 gtgtatctaa atcgataccg aaactttcac aagcctgcgc taacatttga ggataatact
     9061 gagagctgat tggattccat ggaacgatag caccttgact aagtgtcttc gttctatctg
     9121 gaatcactaa atcttgatcg acttctaatt tgacacctaa accatcacag tctggacaag
     9181 ctccaaaagg cgcattgaat gagaacagtc ttggttctag ttcgccaaca gtaaatccgc
     9241 aataaggaca ggcatagtgt tcgctaaaca acatttcttc ttcaccgatc acgtcaacca
     9301 gagcatagcc gtctgctaat cgcagggccg cctctaaaga atcaaatagg cgagaacgaa
     9361 tcccttcttt cacaatgatc cggtcgatga cgatcgcgat atcatgtttt ttgtttttct
     9421 ccagctcagg cacttcactt aaatcataga tctcaccatc gactcgaacg cggacgtatc
     9481 cctctttttg gattcgttcg aatatttttt tatgttgtcc ttttttcttt accacgatcg
     9541 gtgccaacac ttggatcttt gtgcgctcag gcaaagccat tacttgatct gccatttgat
     9601 ctactgattg actggtaatc tcgatatgat cgttgggaca aatcggatgt cctacacgtg
     9661 caaacaacaa gcgtaaatag tcattgattt ccgtcacagt acctactgtc gaccgaggat
     9721 ttttacttgt tgttttctga tcaatagaaa tcgccggact caatccgtcg atgctatcta
     9781 cgtccggctt atccatttgt cctaaaaact gacgagcata agcagaaagg ctctctacgt
     9841 atctccgctg cccttcagcg tacagcgtat caaatgctag ggaacttttt ccagaaccgg
     9901 acaaacctgt aacgaccacg aatttatctc gtggaatcgt tacatctata tttttcaagt
     9961 tatgggcacg tgcaccatga atcgtaattt tatcgttagc catgttgtcc tcctactttg
    10021 aagcttttaa ttctaaaatc atatctcgca cattcgcggc tgtttcaaaa tccaaagctt
    10081 ttgccgcatc tttcatttct ttttctaatt tcatcaataa cgtgtctttt tcttccttcg
    10141 tcatttcttc gtacgagact tgtaccgctt cttttgtatc atcttccgat tctttcgtaa
    10201 tagaaatcaa atctcggatt tctttaatga tcgtttttgg aacgatccca tgttcttcat
    10261 tgtacttctg ctgaatcgta cgacgtcttg acgtttcatc catcgctaga cgcatagaat
    10321 ctgttacttt gtctgcgtac atgattactt taccttcttc attccgagca gctcgtccaa
    10381 tcgtttggac taaggaacgt tcactacgta aaaagccttc tttatccgca tccaagatag
    10441 caacaaggga aacttcaggt acgtctaatc cttcacgaag caaattgatt ccaactaaca
    10501 catcaaattc acctaatcga agatctcgaa tgatttctgt tcgttccagc gttttgatat
    10561 cactatgcaa atatttgact ttgatcccta attctttgaa ataatctgtg aggtcttctg
    10621 ccattttttt cgtcaatgtc gttacaaaca cccgctggtc tttttcgact cgttcattta
    10681 tttcgcctac tagatcatcg atttgtccca tgattggacg aacttcgatc actgggtcaa
    10741 gcagccctgt cggacggatg atttgttgga taacggtatc tgtttgttca tgttcatatg
    10801 gtcctggcgt cgcagagaca taaatgatct gattgacatg tttttcaaac tcttctaacc
    10861 gaagtggccg attgtctaaa gcagatggca aacggaaacc gtaatctact agcatctgtt
    10921 ttctcgctcg gtcaccatta tacattcctc tgatttgagg catggttacg tgcgattcgt
    10981 ccgccacgat caaaaaatct tcaggaaaga aatccaatag cgtataaggc ggttcacctt
    11041 ctttacgtcc gtccatatgc cgagaataat tttcaattcc cgacgtgtag cccatttcta
    11101 acatcatttc aatatcgtaa ttggttcgct gttctaaacg ttgagcttcc agaagtttgt
    11161 tttcatttcg caagacagtt aaacgctgtt ctaattccgc tttgatattc gctacggcat
    11221 gctccatatg ttcatcattc gtcacaaagt gagtcgccgg gaagattgct acgtgttccg
    11281 tttctcctaa aacttcacct gtcagtgcat tgacttctcg gatacgttcg acctcatctc
    11341 caaaaaactc cacacgtaag gcacgttcat ctcttgaagc cggaaaaatc tccacgacat
    11401 caccgcgcac tcgaaaacga ccgcgctgaa aatctatatc atttctttcg aattggatac
    11461 tgactaagtc acgaatcaac tgattgcgat ctagttctgc tccctgtcga atcgaaacta
    11521 cttgtttttg gtactcaaaa ggcgagccta atccaaaaat acatgaaacg gatgcaatga
    11581 cgatcacatc atttctttct aataatgaac tagtagccga atgtcgtaat ttgtcgatct
    11641 catcatttac acttgaatct ttttcgatat acgtatcgct tgaaggcaca taagcttcag
    11701 gctgataata atcataataa gaaacaaaat attcaacagc attgttaggg aaaaattcct
    11761 tgaattcccc gtacagctga ccagccaatg ttttgttatg ggcaataatc agtgttggtt
    11821 tattcacttt ctcaataaga ttggaaatcg tatatgtttt ccctgttcca gtcgcaccta
    11881 ataagatttg tgcttttttc ccgccgacta cgccatccac taattggtta atcgcttcag
    11941 gctgatcacc agccggttgg tatttcgaga caagctcaaa gtgtcgggag gtatctctct
    12001 caatcattct tcgtcctcct tttcattcat tccttttcat tttacgacca ataaaaagaa
    12061 aaggaaagca aaggcattcc ttactaaaaa attataccac accgaacata ctttcgccac
    12121 ttttttatct tattatacat gttatgtttt ataacataaa atgttagaaa ctcgcatttt
    12181 tttcattttt tcgagcttac agtcttgtct gattcagcac ttttcgccta taataataaa
    12241 atattggaaa tttaggaggt tgattatgaa aagaaagcat ttatttcact catttgtttt
    12301 cttaatgaca ggacttgtga cacttgcgtt tggtcatgtt gcacaagctg acaacactac
    12361 aacggcagag tcaagcacaa gcgagacaat gcaaaaaata gagcccaaaa aagacgtata
    12421 cgtaattgcc agtgactctg cttttgctcc atttgaattt caaaacgcaa agggcgagta
    12481 cgaaggcatc gatgtaaaat tgatggaaaa catcgccaaa ctgcaaggat ttaacatccg
    12541 aatggactac cgtggtttct ctgctgcttt gcaagctttg gaatcaggac aagcagacgg
    12601 aatgattgcc ggaatgactg taacagatga acgaaagaaa agctatgatt tttctgattc
    12661 ttactttgat agcgggatcc aattagctgt caaaaaagga gatacttcga tcaagtctta
    12721 tgaagatttg aaaggaaaaa cagtcggagc aaaagttggt accgaaagtg ctgaattttt
    12781 aagcgaccat gaatctgaat atggctattc tatcaaatat tttgatgctg ctgatcaatt
    12841 gtacgacggg ttaaaagttg gcgcaatcga tgcaatgatg gatgattatc cggtaatcgg
    12901 ttatgcgatc aaacaaggac aagaattgga aacaccgatc aaaaaagaat ctggcggaaa
    12961 atatgcattt gccgttaaaa aaggacaaaa tcctgagctt cttaatatgt tcaatgaagg
    13021 attgaaagaa ttaaaaagaa caggcgaata cgataagatt attaaagaat atgtagcgga
    13081 tggttcagaa acttccagtg agtcttccac tgctgatgaa tcaacatttc ttggacttat
    13141 ccaaaacaac tatcaagcat tgttgaaagg actttggaga acaattctcc taactttgat
    13201 ctcctttgct ttggctatag taatcggtgt gatttttgga ttattcagtg tagcaccaat
    13261 acgcgctctt cgcacaattg ctagtattta tgtcgatatc atccgaggaa ttccaatgat
    13321 ggttcttgcg ttctttattt tctttgggtt gcctggtatc gttggattta cgattcctga
    13381 cttccttgct ggtgttatca ccttgactct taacgcaagt gcttatatcg cagagattgt
    13441 tcgaggcggg atcaacgccg ttcctgtcgg acaaatggaa gcttccagaa gtttaggtct
    13501 ttcttataat cggacaatgc aaaaaatcat tttgccgcaa gcgatacgca tcatgatccc
    13561 atcattcgtc aatcagttcg ttatctcatt aaaagacaca acgatcattt ccgcaatcgg
    13621 tgtagtcgaa ttgctgcaaa ctggtaagat cattgttgca cgtacaacac aaagtacgta
    13681 tgtttacttg atcattgcga tcatgtactt gattttgatc acagcattga caaaattagc
    13741 aaaagtttta gaaaagaagg tgaagtaaga tggcagaaaa aatcttagtt gagcatttag
    13801 tcaaaaaata cggcgataac acagtattaa acgacatcaa tgtatccatc aacgaaggag
    13861 atgtcgtctg tatcattggc ccttcaggtt caggaaaaag tacattcttg cgttgcttga
    13921 atcgtttaga agaaccttct gacggtgaaa ttattattga cggcgcccac ttgatggata
    13981 aaagcacaga tatcaacttg gtgagacaac atatcggaat ggtattccaa cactttaacc
    14041 tattccctca tctttctatt ttggaaaaca tcattttagc accgatggac ctgaagaaag
    14101 aatctagaga agaagcagag aaaaaagcaa tcaaattact gcagacagtt ggtctagaag
    14161 ataaaaaaga tatgtatcct gaaatgcttt ctggtggaca aaaacagcgt gtggctattg
    14221 ctcgtgctct agcgatgaac cctgacatca tgctttttga tgagcctact tctgcactcg
    14281 atcctgaaat ggtcggtgat gtcttgaacg tcatgaaaaa gttagcagaa caaggtatga
    14341 cgatggttat cgttacgcac gaaatggggt tcgctaaaga agtggccaat cgcgtcatgt
    14401 tcattgacga cggaaacttt ttagaagatg gaacgcctca acaaatcttt gaaaatccgc
    14461 aaaatgaacg gacaaaagat ttcttgaata aagtattaaa tatttaataa aaaccaaaaa
    14521 tgcacggtcg ccatgaaggg accgtgtatt tttatcttct tattttctca cctaatcgta
    14581 tcagccgcat cgcttgtttt cctgcacaaa caagcaatcg ctctacctgt tccatcgcat
    14641 aagaaagtac catcggttca ttgatgatat caagtacata gtcgatacca ccctcactta
    14701 attgagcttg atttttcttc tccatattat gtagttgtgg gacaactttc tgacaatcag
    14761 caattgtgtc aagaacggat caatccttta ttggagttgc tcgaaagggt cttctcttat
    14821 tacggacagg ctttgctcac tgtacataga caacaaatca ttatcctagt caatcggatt
    14881 tccagagcct cattgctatc attgcttgat aaaatccaga caaagtttaa taaaatgtat
    14941 cagttacagc taaactttgg aattgggtcg ctttgttata cagagcaaga gacaccgcaa
    15001 tctttccttc atgccaaaca agtttgcgaa tggatagctt tccatcaatc tgtgaacgag
    15061 atccgctttt ttgaagattt agacctcggg atcgttttac cagcaatccc gtcagatcaa
    15121 cgaacattat atgtaaaacg tattttgaaa agcctgacag aagaagaagt acatttgttc
    15181 aagaagactt tggcatgctt cagtaaaaat aacggaagca tcaaaaattg ctcagaagaa
    15241 ttatttattc ataaaaacac cttgcaatat cgattgaaca agttccattc tctcactggt
    15301 tataccccta gaaactatga cgattatcat attctaaagc tggctttttt gttggtacaa
    15361 acatgacaac tac
//
LOCUS       DAFEML010000057        15229 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFEML010000057
VERSION     DAFEML010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.058"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            278..787
                     /locus_tag="LP468_002075"
     CDS             278..787
                     /locus_tag="LP468_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2081588.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="LP468_002076"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="LP468_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2081589.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="LP468_002077"
     CDS             2322..3302
                     /locus_tag="LP468_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2081590.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="LP468_002078"
     CDS             3424..4842
                     /locus_tag="LP468_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBL2081591.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="LP468_002079"
     CDS             4913..6382
                     /locus_tag="LP468_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2081592.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="LP468_002080"
     CDS             6392..6859
                     /locus_tag="LP468_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2081593.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="LP468_002081"
     CDS             6895..7767
                     /locus_tag="LP468_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2081594.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7859..10381
                     /locus_tag="LP468_002082"
     CDS             7859..10381
                     /locus_tag="LP468_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2081595.1"
                     /translation="MKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQLFSD
                     GKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLPLIIK
                     GNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKKGAFT
                     GAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEYANVR
                     LILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITIDSKIF
                     CSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWIDPEI
                     SIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESDEFIA
                     LRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFRMKND
                     KQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITASAIAR
                     ETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQMYEKI
                     ESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLSQKKN
                     VIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTICVLST
                     TEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTKLRFL
                     DSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHLKEGA
                     QLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10537..11310
                     /locus_tag="LP468_002083"
     CDS             10537..11310
                     /locus_tag="LP468_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081596.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11303..12094
                     /locus_tag="LP468_002084"
     CDS             11303..12094
                     /locus_tag="LP468_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081597.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12104..12595
                     /locus_tag="LP468_002085"
     CDS             12104..12595
                     /locus_tag="LP468_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081598.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12613..13023
                     /locus_tag="LP468_002086"
     CDS             12613..13023
                     /locus_tag="LP468_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2081599.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13027..14427
                     /locus_tag="LP468_002087"
     CDS             13027..14427
                     /locus_tag="LP468_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBL2081600.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14450..14824
                     /locus_tag="LP468_002088"
     CDS             14450..14824
                     /locus_tag="LP468_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2081601.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5285 a         2135 c         3046 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaat
     7861 gaaagatgaa gtattagagt atatcaaaaa taatttaaag tattacgatt tttctgctca
     7921 agatattgca atgaaatttt gtattaaaag aaatgtcgct tcccactatt tgaatcagtt
     7981 attttcagat ggaaaattac taaagaatga ttctgttaga ccagtaatgt tcaagtataa
     8041 tcaacaaaag ccaaaagact gcttttctaa gtttattgga gcagacatat ctttgaaatc
     8101 cactatagat aaatgcaaag ctactgtaat gtatccccct aatggcctcc cattaataat
     8161 aaaaggaaac agtggcgttg gaaaaagttt tttagcaagt ttgatctatc agtatgctct
     8221 tgatagaaaa gtaattcata atgacgcaaa atttgttgtt gtgaattgtg cagattatgc
     8281 aaataatcca gagctattgt cagcagtttt atttggatat aaaaaaggag cctttactgg
     8341 ggctgaaaaa gatactgcag ggatgctatc ttctgctaat ggaggatacc tttttttaga
     8401 tgaggttcac aatctaagtg cagaaaacca agagaaattg tttcttctta tggattctca
     8461 aaagtatcgt aaacttggtg aaagtgtgca atgggagtat gcaaatgttc gccttatctt
     8521 agccacaaca gaagataaaa atacctcttt gttagcaact tttagaagac gcatcccagc
     8581 tgaaatcact ctgccagatt acaataatag aagtacatct gaaaaaattc aattattatt
     8641 tgaatttctt aaagatgaag caattacgat tgattcaaaa atattttgtt cgattgaact
     8701 ttttactgat cttttatcga aaacatttga aggaaatgtt ggagaattga ggaatgaaat
     8761 caagcttctt tgtgcagaag gttatttagg aaataagaga aagtcttcaa tttatttagg
     8821 ggacaaacta gacagcggtt tttggataga tccagaaatt agtatagatt taaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9001 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9061 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9121 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9181 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9241 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9301 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9361 aacagcttct gcgatcgcaa gggaaacaaa taagttgctg aatacatatg tttatgaggc
     9421 tttcgatatg ccaattgaag gtgagactag tgacttaatt aacctaatca acaatttttg
     9481 taaaagtata gatacgacga atggactcat tctgctagtt gatatgggat cattggaaca
     9541 aatgtatgaa aaaattgaat ccaatgtaat aggtgatttg gtaattttaa acaatgtttc
     9601 tacagcttta gcgattgaat gtgggattca agtttgccaa aaaaagccaa ttagtcattt
     9661 ttaccagatg gattttgatt cgtttcaagt taaagttcag tattataaag gattatcaca
     9721 aaagaaaaat gtaatagtat cttgtctctc tggtgagggg atttctgaaa aagttaagga
     9781 tattttaaaa cggtatctcg ataatcaagt ggagattttg atttttgatt ttaacgcatt
     9841 aaagaaaata gcaaaggaaa aagatactat gatttttaag aatacaattt gtgttctttc
     9901 aaccactgaa ttttacattc aaggaatcga ttgtttaaat ttagaaaatc taattaatgg
     9961 gaatcaaacc ttagaaaaat taaataagta tatggactcg gatagctgtg agttctgctt
    10021 aaatgaatta gttaaactct ttactattga aggcgctagt actaagcttc gctttttaga
    10081 ttccaaaaaa gtattcaatg agatagaaaa agtactatat ttgtatgaaa aatattacga
    10141 tgtcaaaatc ccaagttttc tgagaattaa tctatttcta catctttctg gaatgattga
    10201 acgaattatg attggtgatg gaataacaaa tgaacatttg aaagagggag cgcaactatt
    10261 tgatactttt ttaaatgtat caaaagattt tttttcagaa atcaaagata tttactgtat
    10321 tgaaataccc aaaggagagt atgagttaat ctatacaatt tttgagcaga ctattttcta
    10381 aatagcatac tagcgtctaa aaaaatgaaa gggtgtccaa agtatattta gacgctcatt
    10441 taattaatat ttactgtatt ttcccgcttt attggataat gttagttggc acagtaattg
    10501 cttatataaa agtataagaa gaaaggagag aacaaaatgg cgttttggca aacattttta
    10561 gttgtgttgt atggattttt cattaactgg gataaggaag ggcccaaaat cggaacctcc
    10621 caacctgtcg ttgcaggttt cttgaccgga cttattatgg gagatattca aactggactt
    10681 tatatcggtg ggactttgca attaatgaca ctaggtatta ctagttttgg tggtgcatca
    10741 gtaccggatt atcaaacagc agcattgatc ggtacttatt tagcaatctc aactaaccag
    10801 gatgcttcta taggaataac tttagcaata ccggtagcaa tgttaattgt acaactagat
    10861 gttctaaagt ggtcaacaaa catttttttt caacaaaagg cagaaaaatt cgcacaaaaa
    10921 gaagattatc aaaaattaga gtggatgcaa tatttggcat caattaatac aagctttgta
    10981 tctggaattc ctgttttgtt aactgtgata ttaggcccaa cgttagtggg aagtgcaatc
    11041 aattatattc ctgaatgggt taccggtggt ttaaaggtag cagggggact attacctgct
    11101 gttgggatag gaatgctact taaatattta cctacaaaag attactttgc ctatttgtta
    11161 gttggtttcg ttttggcagt ttatttccaa ataccaattt tagggatttc gttacttggc
    11221 gctgcaatcg cactaatcgt atataaaaat agatcaaata atactcaagt agcaccagct
    11281 gcaacaggag gttttgacga agatgaataa gaaactgaca aaaatcgaca aacaagtaat
    11341 tttccggtgg attctcaatg gtgcaacttc attaaattat gaaaaaatgg aagggttggg
    11401 ttatgcgtat tctatgcttc cttttatcaa ggacacatat aaagatgatc ctgaaggaat
    11461 gaaacaatcc gttttagctc acttacaatt ttttaacact acgccgtata cagcgcctta
    11521 cattattggt atgaatgttg gaattgaaaa agaagaaaaa aataagtctt tggaagcagt
    11581 aagtgctctg aaaacaggtc taatgggtcc tttagcggga attggagata gtgtatttgt
    11641 agttattcca tggactattt ttggagcaat tgcagctaat atggcattgg aaggtagttt
    11701 tgttggaatt attttgtgga tactggcatc aattttatta aggattactg cttatccttt
    11761 ataccttgct gggaaagaat cgggtgcgag cctactaact caaattgaaa caaaattaaa
    11821 gtctattact gatgcagtat caattttagg gttaatggtg gtcggtgcac tcattgccac
    11881 agttgtaaaa gtgaatgttg gctttgaatt taaacaaggc gacttaacaa tgaccggaaa
    11941 tgaaatcttt gatcaagtta tgcctggttt attacctgca tgtgtagtag caattgtgta
    12001 ttatttgtta ggacgaaagg ttaaaccagt ttatgtaatt ctattaatct tagtagtttc
    12061 tattgcgtta agagcgttaa atattttgaa gtaggtgttg aatatggatg aaaaaatgaa
    12121 aggtattata catgttcgta ttgatgatcg aatgattcat ggacaagtag caacacaatg
    12181 gacaaatcaa ttgagtgcta acagaattat ggttattaat aatgaagtag ccaatgatga
    12241 cgtaaaaaaa gctgtagttc gcctcgctgc accacctaat gttagaactt caataattac
    12301 aagggaagta gcagttaaaa atattctttc tggtaaatat gaaggacaaa aagttcttat
    12361 tgttgcagtt tctccaatcg atgttaaatt tttgattgat aacggtttac caataacaag
    12421 tgtaaacgta ggaaatttat caagaaggaa tggaacagaa cgcatccgtc cgacgataaa
    12481 tattactgaa gaagagagag aggcttttaa agaactaatt agtgatggag ttgaagtgac
    12541 agtgatacaa actcctagag attcaaaaga atttttaaag gattttattt attaagaaca
    12601 gaggatgagt ggatggagtt tataattaca tctcatggaa atattgccat tggatttgta
    12661 gatacattaa aaatgttttt tggcgataat ttaaattgtc atgtggtaac acttggagat
    12721 gcaggcattg aagaattccg tgaaaacatt gaaaaaatag tttctcaagt aaaaaatcaa
    12781 gaagttatgg tatttgctga cttgattggt ggaacacctt tcaacgaatt tgctaaaaga
    12841 agtgaagtat ttcaaaatgg gtttcaactt cttggtggca tgaatttagg aattttgatt
    12901 gaggctgtca atttgagatt acaaggaaaa aaaagcgatg atatcatcga aaatctaaga
    12961 aatatgaata caattgcgtg tcttgcagat atgcaaagac atactaacga agaggatgag
    13021 tgataaatgc aaaaaatttt ttacaagcct aaagattttt ggtttgggga ttgcatgcct
    13081 ttttataaag atggaacttt ttatctattt catcaacgag atacgagaaa tcctaaacct
    13141 ttaactgatc cttttgggtg gtcactagtt acaaccactg attttgtgaa atttgaagaa
    13201 tacggggaag taattcatcg tggtggcaac gatgacattg atcaatacat ttacgctgga
    13261 agtattgtcc aaggaatcaa tgagtattta gctttgtata ctggacataa tcgcaaagct
    13321 aagttggatg gaaaaacttc agaagtgtta atgattgcaa gttctaaaga tttaattcat
    13381 tggaaaaagg atggcgaagc agcaaaactt gttcctcaag aaggatatga taagaatgat
    13441 tggcgcgatc cttttgcaat ttttgatcaa gatcatggaa aatacgtttt gatactagga
    13501 gctagaaaac cagcaagtaa gaaaaagccg acggggagat tggtctattt tgaatccgaa
    13561 gatttaaaag attggaattt caaaggagac tactgggcta ataatgaatt taacatgatt
    13621 gaaatgcctg atatatttga aattgatgga acgtggtatt tacttttttc agagtattgt
    13681 gaagataaaa agactaaata tcgagtcgga gcaggattat tttcagattg gaaatcacca
    13741 gtagacgaag ctttcgacgg aaaagcctat tatgcagcaa gaacagtcgg aactaatgaa
    13801 actggccgtt ttctaactgg ctgggtggca acaaaagaag gggagaacga tcaaaataac
    13861 tgggattggg gcggtgcact tgttccacat caaattattc aaaagacaga caaaactctt
    13921 ggtgttaaac tgcctgaaaa aataattgag aattttaaag aaatcactcc attttcaagt
    13981 tttaagttag agaaagaatt tggaaaaaaa gaaagagtaa ttgttcctaa aatcgaagat
    14041 tattttctat ttgaaacaac tttgactatt acatcgttaa caaaggagtt tgctttaaaa
    14101 ttatttgtag atagtgatac tcaagaagga tacgaatttc gtatttcatt gattaataat
    14161 cagcttactt tcggaaaaac tccgaactat ccttggcctc aaatgtttga taaggggctg
    14221 caacgaccac tatttttgga aataggcaaa gaatatgaac taaagttaat tgttgatgat
    14281 acgatagctg ttttatatat tgataatgtt gctttaagta ctagaatgta tgataaagtc
    14341 ggaacagcat taagtatgac tgttacggag ggagcaatca aggtagataa actagactat
    14401 tcaataaatt atgaatgtgg attttaaaac aattgaaggg atgatgtaag tgaaattaaa
    14461 tggtttacaa catattggaa ttccaacaaa agattttgga gcttcaaaaa tcttttatga
    14521 atccttaggg tttagtctga ttaatgaaga aatgaatgtg ggaagtaaag tcggcttttt
    14581 cgagttgaat ggaacgataa tagaaatatg ggaagataaa actactgagt gtagaggagc
    14641 cattgatcat ctagcattag atacggatga catagatgag gtattcaatt caattcaaga
    14701 tttaggatat gaattattag ataaaaatat tatggaatta ccgttctggg aaaatggaat
    14761 ccgttacttt aatttctacg gaccaaatca tgagattata gagataagcc aaatgaagaa
    14821 ataaatagat aacgaagtgc tctaagttgg tatgaacgaa aagtacttca ttttttggta
    14881 tcagcatttc aatagtttaa tgagaattta ctatttcaaa ttaattcaaa gtgacagtat
    14941 tttttactta tttggtttca aattttgtaa tccttcctat ttattggaat acactccaca
    15001 ttttgtatac aagtcatatc atgttttagc aaagctctta ccaagcaaag ttataatgat
    15061 gttttccaaa gtttgatctt tcgatggagg ctaacacata ttttttgcag gacagccaaa
    15121 attagatgta tagaatagag tctgtgaggc gtatagacag tttattgtct gtatgccttt
    15181 ttttattttg aaaaattttt agtatttttc gaaaaatgct cactcctag
//
LOCUS       DAFEML010000058        15013 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFEML010000058
VERSION     DAFEML010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.059"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            5..2377
                     /locus_tag="LP468_002089"
     CDS             5..2377
                     /locus_tag="LP468_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081602.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNDQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQVPEKEQKQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGHTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQD
                     EKNVVETAEQKNIVLVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDTQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="LP468_002090"
     CDS             2438..3898
                     /locus_tag="LP468_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL2081603.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVQDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEMKVEPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGKQQERE"
     gene            3909..5918
                     /gene="topB"
                     /locus_tag="LP468_002091"
                     /pseudo
     CDS             3909..5918
                     /gene="topB"
                     /locus_tag="LP468_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            6034..6183
                     /locus_tag="LP468_002092"
     CDS             6034..6183
                     /locus_tag="LP468_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081604.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6264..6860
                     /locus_tag="LP468_002093"
     CDS             6264..6860
                     /locus_tag="LP468_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL2081605.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            6873..7772
                     /locus_tag="LP468_002094"
     CDS             6873..7772
                     /locus_tag="LP468_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL2081606.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEDIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            7775..8259
                     /gene="ssb"
                     /locus_tag="LP468_002095"
                     /pseudo
     CDS             7775..8259
                     /gene="ssb"
                     /locus_tag="LP468_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            8281..8538
                     /locus_tag="LP468_002096"
     CDS             8281..8538
                     /locus_tag="LP468_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081607.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(8697..8831)
                     /locus_tag="LP468_002097"
     CDS             complement(8697..8831)
                     /locus_tag="LP468_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBL2081608.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            8974..9234
                     /locus_tag="LP468_002098"
     CDS             8974..9234
                     /locus_tag="LP468_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081609.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9683..9889
                     /locus_tag="LP468_002099"
     CDS             9683..9889
                     /locus_tag="LP468_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL2081610.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            9889..10140
                     /locus_tag="LP468_002100"
     CDS             9889..10140
                     /locus_tag="LP468_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081611.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            10156..10593
                     /locus_tag="LP468_002101"
     CDS             10156..10593
                     /locus_tag="LP468_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081612.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            11029..11199
                     /locus_tag="LP468_002102"
     CDS             11029..11199
                     /locus_tag="LP468_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081613.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAKKKQDLRYQH"
     gene            11274..11663
                     /locus_tag="LP468_002103"
     CDS             11274..11663
                     /locus_tag="LP468_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081614.1"
                     /translation="MKKKQTKLSLADILTQLTATEDGVVEFERSEIAVVDDRYFKMPY
                     FFDQAKVICLCGYDGVRDYFGITEEKVVWVNNHTGLGALAFEGTVLDNISIVFEEESF
                     TLECDNLIRYIDPEFYEDKNLAWELAL"
     gene            11645..11911
                     /locus_tag="LP468_002104"
     CDS             11645..11911
                     /locus_tag="LP468_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081615.1"
                     /translation="MGTSFIDRVIVQVKEERKITMKYNSLDHKRMWVEKLEEDLEQLE
                     LLGYNKTSTVYKEGLKRTKKVQKELATLESSVQKKEVELTHAYL"
     gene            11921..12580
                     /locus_tag="LP468_002105"
     CDS             11921..12580
                     /locus_tag="LP468_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HBL2081616.1"
                     /translation="MADKRKEKIQKLLALAADANDEESMSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLASIIAQNFRTEFYYREGSPIDLCFTGLA
                     SDVQIAEITFQYASGSVSYCARKYMQQPEIKRKRKRKWQLKQDYIQGYLSGLSKVFKQ
                     QVLTNGYELALQLPEAVKSYMEDLGLVPGKDTSHKVKDNEAYFHGYQEGLKFKKTELL
                     E"
     gene            12887..13504
                     /locus_tag="LP468_002106"
     CDS             12887..13504
                     /locus_tag="LP468_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2081617.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTPKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            13678..13887
                     /locus_tag="LP468_002107"
     CDS             13678..13887
                     /locus_tag="LP468_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081618.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            14094..14294
                     /locus_tag="LP468_002108"
                     /pseudo
     CDS             14094..14294
                     /locus_tag="LP468_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14781..14960
                     /locus_tag="LP468_002109"
     CDS             14781..14960
                     /locus_tag="LP468_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081619.1"
                     /translation="MTELTADMSDTWLQEYLFPEKQTTARGYLPVDWEYVHKELMKKN
                     MTLKLLHREYGVHGT"
BASE COUNT         5533 a         2471 c         3128 g         3881 t
ORIGIN      
        1 ggacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaatga tcaaatcgaa aagatgtttg aacaccaaag
      121 aaagaccaac ggtcaaccaa tgaacgataa gagaaacggg cattcttggt ttaggcaaca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggttataaca agtacggtgg
      301 cctggatatg acgatcgaaa atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ctgccacgat ccgaaaatac caacgaaaat tggaaacatt
      421 agaacagctg aaagaaaaat cagagaaagg aaaagaaaat attcttcctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaagaat ccaactatct attttctgaa
      541 aggctatcga aaagtcgctt tagaactcaa tgaaaacggg ggatttgagg aatctaaaaa
      601 ataccaagcc acgtcggaag aagaaaaggc agctgttcgt gaattacttg aagaagctac
      661 acctactgat tctgtgaagg agaaagaaac cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gcaaaagggt tgaaaagtta tggtggggag atcgtaacac tagaattgat
      781 cgatcaactc aaaacactgg ataaccaata cgccgcagaa gcaggctatt ataaattcta
      841 ttttgaagaa gtgaagaatg gagaagtagt agatcagata cgaatggatc taggggatgg
      901 cgtcaatagt aatcacccca tctatttaga gttagctaga ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaaacag tcaaaaatga acctatttca aaagtacaaa atgagattaa
     1021 agagacaaaa acaaaacaaa agggttatca aaaacgaacg gcagaagaga ttaagcaaga
     1081 agtcaaatca ctttcccaac aggcgcttga tgcggtgaaa aagcatactc attcacctga
     1141 agacgtcaaa gaacttttga attttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatc gaggaacaat ttccaggcgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagagg ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca attgaagcct gaagactatc cgaaaatctt
     1501 cccgaaccgc gtctttgatt ttcaattgga tcaaacaggg catacagaac ttcaagttgg
     1561 gattcaagcg gtagccaaaa atattggaat tcaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtacgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcca caagtattca
     1741 cgaattagcc catgctagaa tgcacaaatt ttcagaatta gatactgcaa caaaagaact
     1801 acaggcagaa atgacctcct atattgtgtg caagcatttt gggatggaca cctcggagaa
     1861 agctattcct tatattgcga catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagtcgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccagc cagcagaagt
     2041 gaagcaggat gagaaaaatg ttgtagaaac agcagaacaa aagaatattg tgctcgttgg
     2101 ctcactttgg atcgacaaga aagacgggaa agtcctggaa gaagacacgg gccgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tacgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agattcaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattattt
     2821 gaaggaagaa cgaaaactgc ccgattggtt gattgattat gcagaaaaag aaggattgat
     2881 cgccgaacta aagccaaaac atgaacggca aaatttctta gttcaagacg atcgtttgga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaaca ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggatttaa cctaaagatc ggtgacccta aacagttaaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccattg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagttga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaagtcattt atgaagaagt tgcaaaagaa atgaaagttg aacctgaagc
     3481 aattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtctt ttggtcagca gctttctgtt aacgattcaa tagaagctat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaaggttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg ctcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggatt ggaatgatca attgaagcat gaaatccacc aacaagagat
     3841 cagaaagcaa aaacgtgcga tgttgtttca acaaggcaaa caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccacc cgaaaagacg ggtattttga aatccaagat cggttgtttc
     4021 caggagaaac tgtgatcacg tatggttttg gtcatttagt cgagttagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagagcattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatagctt
     4261 ggacgatcat tcaacaagca ggcgccgatc atggaaagat atttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagt gattccagca attacgagac gcagaagaga
     4381 cctatcccaa atttgaagaa gcacaagcac gccagatcgc tgattggttg atcggcatga
     4441 acggcagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agtttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca gctgcaggaa aagattagaa
     4561 acttccaaaa agaaccatat tttgaaggaa aagcccaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatcca aatgaaaccc aagcgacaca agaagcattt gaagcctatt
     4681 taaaagaaaa aggtgttcaa ttaggaaaac agccaggtac gatccttcaa gtcgaaacag
     4741 agaaaaaaag tgcggctagc ccacgtcttt tttctttatc gagccttcag tctaaaatga
     4801 atcaactcat gaaagctagt gccaaagata ctttggaagc catgcaaggg ttgtatgaag
     4861 gaaaatatct aagctatccg cgaacggata ccccttatat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttaaa agccgaagcg attccgactc
     4981 ctattcatac accgaatagt cggtatgtga ataataagaa agtccaggaa cattacgcga
     5041 tcattcctac aaaaacggtt atgacagcag cggcttttga acaactaagt ccactgcagc
     5101 aggctattta tgaacaagtg ttaaaaacaa cggtggccat gtttgcggaa aagtatacct
     5161 atgaagaaac aacgatcttg acgcaagttc agcagcttca gttaaaggca atcgaaaagg
     5221 tgccgctaga tctaggttgg aagaagttat ttggaaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggtg gatctacaag
     5341 ttcttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcaa
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagctcgtgg tgacgaataa agggattttg ctttgccaag
     5581 ccgtggaaaa agagccgctg cttacgagcg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat cggtgaacga aaaggaacac aaaccacttt tctagccaat atccaaaaat
     5701 ttgtctctca cttattggaa gtcgtaccag ggcaaatcca atccactgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaaagg tcagaagggt tcatttgaag caacgattgt tttaaaagaa
     5941 gacttcacta caggctttga attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca
     6001 cgccgcactg caaaataatg gagggttaat cttatgcgta ataccacaca caaacaacaa
     6061 gaaatcgaaa atcaaaaagc caaaattcgt tcagaacagg aaaaaatgcg tgccagcaaa
     6121 cgaagactgc agcaattgaa gaaccagcag aggattcaaa aagaaatcga attagatcga
     6181 taaaatcttc ctaactattg tatacgtata aacttatgtt atactgtttt tataagttta
     6241 tacgtataca aaggagggag aaaatgacaa aagcaatggt atacaagctg ctagaagaat
     6301 ttaatggaac tttggctttg aaggatgcca aaaaagcggg catttctcct gtaacgatca
     6361 aacgtatggt agatcgaggg gagctggatc gagagtatcc aggttttttc accttacctg
     6421 gtcaatttcc tgatgaattg tttatggcgc aaaaaaaata tgaacgcggc attatttcac
     6481 atattaccgc gttagatttg tatgatttaa cagatatgat ccctagacag atcgatctga
     6541 ctgtacctta cggttatcac gtttctgaaa aaggattgaa ggaattcgca gttgagctac
     6601 actatacaaa agcggaatgg tatgaattag gtaagattga aataaaaagt cgctatggga
     6661 atcctattat agcttatgat ccagaaagaa ctttatgtga catttggaat ccctggtata
     6721 ccgttgagga tgaaatcaaa gtaaaagcaa tcaaaaacta tatggagtcg gacagaaaaa
     6781 atcttagaaa attgaatgag tatcgacgaa ttttaccaac agacaaaacg atgcgttctt
     6841 atattatggc tttaaattaa aggagaagat acatgacacc tacgcagtta aaagcaaaag
     6901 tgaagaatat ttctagagaa aaagaagttg atccgcagct tgttttaaga cattttatga
     6961 tggaaaaatt cttggaaaaa atctcagagt ctccttatcg tgaaaatttt gtgttaaaag
     7021 gcggcttctt gattggctca aagtatggca ttgaaaatcg cacaaccaaa gatattgata
     7081 cgactttacg ggaaatgaaa gtaaccaaag aaacattaac aacggttcta aacgaaattt
     7141 tttcaacgcc gacgaaagaa gacattcaat ttgagattca aggaatgaaa gaaacgagag
     7201 aagccgatta ctatccagga tttagcttac gtgtgctggc acatttggaa aacatgcggc
     7261 cagattttaa ggtagatgtg actacaggtg actcgatcta tcctgcaacg atcactcaca
     7321 gtcataaatt gatgtttgag gatcgaacga ttcctttgga atcctatcct acagaacaaa
     7381 ttattgctga aaaattaagt gcaacctttg attttttaac agataattcg agaggaaaag
     7441 atttttatga tctctatact attcctaaaa tggagaagat cgatgagaag accttgaaag
     7501 atagtgtgag aaatacattt acacgtcgag gaaaaactga tccgttaaag atatactatg
     7561 aaaaggatat ggatgtactg aaaaatagtc acgagctaaa agatacctgg aagaaatatc
     7621 aaaaaagcaa tccttatgct gcatcgatca cgtacgatga gacaatggat tcgattagta
     7681 atttgatgga aaaagtgatt cacgtcgaag aaaaagagca aaaactagct tatcaaagac
     7741 accaacagat gaatagagaa atggagagat aaagatgatt aataatgtga cattagtagg
     7801 acgcttaacc aaagatcctg atttacgtta taccgcaagt ggtactgcag tagcgacttt
     7861 taccctagcc gtcaaccgaa atttcacgaa tcaaaacggc aatcgagaag ccgattttat
     7921 taactgcgtg atttggcgca aaccagcaga aacaatggcg acattagcta aaaaaggtag
     7981 cttgattggt gtagttgggc ggattcaaac gcggacttac gacaaccagc aaggacaacg
     8041 tgtatatgtg actgaagttg tagcagataa ctttcaacta ttagaaaata aagcagcgac
     8101 agagagccgt gcgcacgctg atcaatcgtc caccagtcca agcaccgcca cctttgaaca
     8161 acggatacag cgacgcctaa caacaatgga ttgaacgctt cacagaatcc atttggtgga
     8221 caatcaatcg atattagcga tgatgatcta ccgttttagt ttgagaaaga aggagtaagc
     8281 atggcaaaaa aaattagtct gacgatggat ctattgatac ccgtaattgc atttatagac
     8341 gggatttctt tgggcgtcac tgaaaatcct ttggtaaata gaattgcgaa aggatcacta
     8401 tttcttgtat tcgtgtatct tgtctgttct tatcttttaa aaagagcagg aaaggataat
     8461 tccttttggc gattgactaa agtcacagta gcagcgacag ctgttatact tacggctatt
     8521 ctaccgcttt atatgtagag ttaacgggaa atcgttgaac ttcttgcgaa atattgctat
     8581 aatgaacatg aaaaagagga gttgcgctaa caacccctca ttaacagcac cgattaaaga
     8641 acggtggcag aatattagtt atttggaaat aaccgctgac ctgctaaagt agacggttat
     8701 ttctttttgt catttttaag catatttaca atcaaactaa tcaaagcaat ggtaaacata
     8761 ccaaaaccaa gaatggtttg aattgtctca tatgcggaca aaaggcttac tccttttata
     8821 gattttagca cttacattca taagcaccac cacctttcca gaagtcgcca ccgtcttcaa
     8881 actttactgt cttgactatt atagcatatc taaaatcgaa taaaaattct caattttaac
     8941 tgtttttgct ataattttag cgaggtgatc gtgatgaaca aatatgttgg tttgcttgat
     9001 aaaatccgag taataaaaac acaaccatta ttggttcgct ttactttaca aacaattcat
     9061 gaatcgatta attgtgtagt tgcagatatt gaaattatcg ataaattgtt aattatggat
     9121 gatggaaaat acaatattgc cgtcacaggt catttcaata aacggaatca attagtcatt
     9181 gaatcgatgc aaattagaaa ccctgatcat tttacgcgat caatgggcat ataaataaaa
     9241 gaagagctgc aatcctaatg taggactgca gctctttttg ttttacatag aaacaggaag
     9301 aaagggaaag gcctgtttag gaaggcacaa gtgccttctc aattgaaaaa cctttctctc
     9361 actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat
     9421 aaggggtctt gctttgtaag acaaaatagg aaaagcttcc tctcaccaaa aggttcgttc
     9481 ctgttcgcta tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa
     9541 aagcgacaag gacaagggta aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt
     9601 gattcattct ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc
     9661 ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat tatttgggtg ttcccttcag
     9721 cgaattattc ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc
     9781 gaaatgtatc aaaagctatt gtttgtatca atgtccaaca tgcgggaaaa aatatacctt
     9841 gtcttatggc gattatattt tgattgagga gaaaggaaag aaacgctgat gaaaacacaa
     9901 cacaaattat tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct
     9961 gaaaaagtag cagaagcttt acttattccg cggtactgga cgatagaaac ccctttagta
    10021 gaggatgcac cgactatgct atttgaagac ctagtgaaga ttgcaggatg tgaactgcat
    10081 tatcaagaaa acttggaaac ttatgaaaac gaatattggt taaccaaatt agagaactaa
    10141 aaaggagaaa aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat
    10201 aaaatggcac aaaaaatgga ggatatgacg ttcctataca acgaaacacg tgttccaaaa
    10261 aaacattata aagaaaaatt gtcggtagct gtggaagaaa tgattgaatc aggtgtcgaa
    10321 atgaatctta ttgcgacgta ctatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa
    10381 tggtttttcc aagccttact atgctttgaa ataggtgtca aaccaagcac tattaaacct
    10441 tctgaatacc aggctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagccaag
    10501 actgtttcaa gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatattac
    10561 accatgaaaa aggaagacaa cgaaaatgaa taaggtgatt tatcaactaa caacggattc
    10621 catatcaacg atttgaaaga aaaaaaggtc aataatcatt tataccgaaa agtgagaatg
    10681 tgtggaataa ggacaaaaaa agcctagtaa ctaagggaat ggttcttatt tcgcaccaac
    10741 cgcccccgcc gcttaggtgg tgcgaaataa acgggcaaag cccgataact taagagaaag
    10801 aaggtgatcc atttgaaaaa gattattccc ttattgttag tactgtttgt tggcgaaata
    10861 cttatgcgag atagtgcagc tgtacagtta aacctcgctg tatttttggt aatactggtg
    10921 ttttgtttga tcttttggcg gtttgtatta gtcctcgtga gtctactatt caagatgatt
    10981 gcagccatat ttttcatggg gttatttcga tgaaaggaga gagtaccaat gccaattgca
    11041 ataggaaata aacggttacc cgtgacatta gatgaaaaga gacaaaaaga attgcagcaa
    11101 ctaaagcaga agtacggcaa aagtgaatcc aggattatgt gtattgcgtt agatttattg
    11161 attgccaaga aaaagcagga tttgaggtac cagcactaag aaagtgacgt cactttttat
    11221 actaaaacct aaaagtgata tcacttttaa acaatggaaa aggtggaaat aagatgaaga
    11281 aaaaacaaac taaactatcg ttagcagata ttttaacaca gttaaccgca actgaagatg
    11341 gtgttgtaga atttgaacga tctgaaattg cggtagtaga tgatcgttac tttaaaatgc
    11401 cttacttctt tgaccaagca aaggtcattt gcctttgtgg ctacgatggg gtacgtgatt
    11461 actttggaat tactgaagaa aaagtcgttt gggtaaacaa tcatacagga ttaggtgcgt
    11521 tagcctttga aggaactgta ttggacaata tctctattgt attcgaggaa gaaagcttta
    11581 cgcttgaatg cgataattta atccgatata tcgatccaga attctatgag gataaaaacc
    11641 tggcatggga actagcttta tagatagagt gatagtgcaa gtaaaggaag aaaggaagat
    11701 caccatgaaa tacaattcat tagaccataa aagaatgtgg gtagagaaat tagaggaaga
    11761 cttagaacag ttggaattgt taggttataa taagacttca acggtgtata aagaagggct
    11821 aaaacgaacg aaaaaagtac aaaaagaact agcaacactg gaaagtagcg ttcagaaaaa
    11881 agaagtagaa ttaacacacg cttaccttta ggagtagaaa atggcagaca agagaaaaga
    11941 gaagattcaa aaattactgg cgcttgcggc ggatgcaaat gatgaggaat caatgagtgc
    12001 attagccaaa gcccagcaat tgatgatgga ctatgatctt actgaagatg agattttcaa
    12061 ttatcatgag cagcaacgga tagaagcagt agaaacgcac gtgatctatc gtggacgtcc
    12121 gcaaaaatgg ctgtatcgtt tagcgtcgat tattgcgcaa aattttagaa cagaatttta
    12181 ttatcgagaa ggatcaccaa tcgatttatg ttttactggc ctagcttcag acgtacaaat
    12241 cgctgaaatt acttttcaat acgcaagcgg aagtgtctcc tattgtgcaa gaaagtatat
    12301 gcaacaacct gagatcaaac gcaagagaaa acgaaaatgg caattaaagc aagactatat
    12361 tcaaggctat ctcagtggtt tatctaaagt atttaaacag caggtactta caaacggata
    12421 tgaattagca ttacagcttc ctgaagccgt gaagtcttac atggaagatc tcggtttagt
    12481 tcctggaaaa gacacttcac acaaagtaaa agataatgaa gcttacttcc atggatacca
    12541 ggaaggatta aaatttaaaa aaacagaatt actagaataa gaagtgcgcc caacagggta
    12601 taccctgttg ggctcttggt gttctattga atgtaaatga gtgtcatttt tatatttaat
    12661 tggcacagtt ttttctaatt atttgtcata ttcatagtca actatagcta caaaagcaac
    12721 taattttgga gatagattga gatatttaaa aatctatcat gaaaaattag ttgcttttgt
    12781 cacttagcgc tgaaaattta tgccatttat ctagaaaaat gacaacagag ttgggcaaca
    12841 gaatttaaaa atgatccgga tttcagaatt ttaaaggagt tttattatgg cgaaaattgg
    12901 gtatgctcga gtaagcagct tagatcaaaa tttagaccga caattagaat tattatcaga
    12961 gtgtgataaa atttttagtg ataaagcaag tgggaaagat accaatcgag aaggatttca
    13021 agaaatgatg aaattcatac gtgaaggtga tattgtcgtt gtgacagaat taaaacgact
    13081 tggacgaaat aataaagagc taacagaaac gatgaattta attcagctga agaaagctac
    13141 actggaagtt ttgaatttgc cagcgttaac aggtatcact gatgataatt tacgtcgatt
    13201 acttaataac ttaattatcg aactatacaa gtaccaggcc gaagaagaac gtcggtatat
    13261 tcgcgaaacg caacaacaag gaattgcact cgctaaagca aaagggaaat acaagggagg
    13321 tacgccaaaa tatcgtgaga atgatccgcg acttcaatta gcatttaatt tgtttttgac
    13381 tggatctaca gataaagaag ttgaagagct aacagggatt aatcgtagaa cgtttagaag
    13441 atatcgaatg aaacatggta ttactaatga agttagggag caaaaaaata aatctttcag
    13501 ttgaggctaa tataattttg caagaaaggg atttttatga aagaaattag attttcaaat
    13561 caaaatatgc agaattacta taatgaaatt atgaatatgg aaactagtga attgaattta
    13621 attatagccg aaaaaaaagt tgcattggat aggaataaaa acttattaaa tgtagttatg
    13681 atctgttata tttcatttct aatactaggt cttccacaag cagtgtttcc tgaaatgttt
    13741 tctggagact ggggtattgt cagctattct atattaacat tgattgctat ggttttaggt
    13801 acttcatttt ataatgcttt tgtaagtaag catgttgagg aatatgaagt attaatgtac
    13861 ttaaaagaga aaaaaacaag taattaatat gagaacacca cgcatagttt ttattttgag
    13921 atatcctaga atgaaacaca ttaagaacga aagcaaagca aaagacggca gaacttctac
    13981 taccttctaa gttttttcat atttgtttgt tatgctatac atagatctgc ataattagac
    14041 ttgcgctgcc cgttattgaa gtttcaggca gcgctctttt tgggggatcg ataatggaag
    14101 aagaaaaaat atttgagaaa cgctggcagc tagcatcaag tgaacaaaga gcaagataca
    14161 ataatttgat cacctcctac cccactgttg actagacata taaggaaaag aaatacttac
    14221 tttggctgtg ccagttagat atagatacct ttgaaacatt tgaagtgatc ctagataaaa
    14281 ttaaacagaa ttgatcagaa acaagcgaag ccttctctcg gttcgcttgt tttgctattt
    14341 attagttggc tcagggcaat tctaagctcg tttgaaagaa aaccgatgga taatcccctt
    14401 gtttgtacca ctttagaata catggatgta cgtattacca ttgactccta ttagttactg
    14461 aaaaaaaatt taaacaagtt gagtattgca gataaatagc tccagtgagg tgaataactg
    14521 ctccactcaa ggcaatagat agctccatcc agggcaacaa actgctccac tttcatattt
    14581 aatagatgaa taaccttctg tataatagaa aggcatacct ttcggtatga caacttatac
    14641 aggatgttat tttattggtt cactatcgaa aaattttgga gctttatttt tccggtattt
    14701 ctcaacgaac gattagttca actgtgggaa gctccagaca tacgattcga gaagttactt
    14761 ctcgagcaga caggaagggg gtgactgaac taaccgctga tatgagcgat acttggctgc
    14821 aggaatatct ttttccggaa aaacaaacaa cagcacgagg ttaccttcct gtagactggg
    14881 aatatgttca taaagaacta atgaaaaaga atatgacatt gaaactcctt catagagaat
    14941 atggggtgca tggaacatag aaacgaaaat gcacggtaga aaagcgaatg aatgtagtat
    15001 aaactctaca aat
//
LOCUS       DAFEML010000059        14237 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFEML010000059
VERSION     DAFEML010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.060"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LP468_002110"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LP468_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL2081620.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="LP468_002111"
     CDS             complement(1819..3042)
                     /locus_tag="LP468_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL2081621.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="LP468_002112"
     CDS             complement(3073..3912)
                     /locus_tag="LP468_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2081622.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="LP468_002113"
     CDS             complement(3929..4609)
                     /locus_tag="LP468_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081623.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="LP468_002114"
     CDS             complement(4611..5684)
                     /locus_tag="LP468_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2081624.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="LP468_002115"
     CDS             complement(6331..7002)
                     /locus_tag="LP468_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2081625.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LP468_002116"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LP468_002116"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL2081626.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="LP468_002117"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="LP468_002117"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL2081627.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="LP468_002118"
     CDS             complement(10885..11751)
                     /locus_tag="LP468_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2081628.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="LP468_002119"
     CDS             complement(11911..14004)
                     /locus_tag="LP468_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2081629.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4133 a         3050 c         2420 g         4634 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtaca
//
LOCUS       DAFEML010000060        13807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFEML010000060
VERSION     DAFEML010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.061"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP468_002120"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP468_002120"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL2081630.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="LP468_002121"
     CDS             complement(2260..2511)
                     /locus_tag="LP468_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL2081631.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="LP468_002122"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="LP468_002122"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL2081632.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="LP468_002123"
     CDS             3461..3679
                     /locus_tag="LP468_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081633.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="LP468_002124"
     CDS             complement(3968..4480)
                     /locus_tag="LP468_002124"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL2081634.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LP468_002125"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LP468_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL2081635.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="LP468_002126"
     CDS             complement(6933..7376)
                     /locus_tag="LP468_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL2081636.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="LP468_002127"
     CDS             complement(7377..8165)
                     /locus_tag="LP468_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2081637.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="LP468_002128"
     CDS             complement(8162..9103)
                     /locus_tag="LP468_002128"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL2081638.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="LP468_002129"
     CDS             complement(9280..9867)
                     /locus_tag="LP468_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL2081639.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LP468_002130"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LP468_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL2081640.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="LP468_002131"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="LP468_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2081641.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="LP468_002132"
     CDS             complement(12784..13719)
                     /locus_tag="LP468_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2081642.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3095 c         2435 g         4469 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataac
//
LOCUS       DAFEML010000061        13743 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFEML010000061
VERSION     DAFEML010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.062"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            13..1464
                     /locus_tag="LP468_002133"
     CDS             13..1464
                     /locus_tag="LP468_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL2081643.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            1813..2445
                     /locus_tag="LP468_002134"
     CDS             1813..2445
                     /locus_tag="LP468_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBL2081644.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3033..4472
                     /locus_tag="LP468_002135"
     CDS             3033..4472
                     /locus_tag="LP468_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081645.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4767..4985
                     /locus_tag="LP468_002136"
                     /pseudo
     CDS             4767..4985
                     /locus_tag="LP468_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5234..5449
                     /locus_tag="LP468_002137"
     CDS             5234..5449
                     /locus_tag="LP468_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081646.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5666..5922)
                     /locus_tag="LP468_002138"
                     /pseudo
     CDS             complement(5666..5922)
                     /locus_tag="LP468_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6109..7020)
                     /locus_tag="LP468_002139"
     CDS             complement(6109..7020)
                     /locus_tag="LP468_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2081647.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7039..8043)
                     /locus_tag="LP468_002140"
     CDS             complement(7039..8043)
                     /locus_tag="LP468_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL2081648.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8040..10163)
                     /locus_tag="LP468_002141"
     CDS             complement(8040..10163)
                     /locus_tag="LP468_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2081649.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10168..12615)
                     /locus_tag="LP468_002142"
     CDS             complement(10168..12615)
                     /locus_tag="LP468_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2081650.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12602..12991)
                     /locus_tag="LP468_002143"
     CDS             complement(12602..12991)
                     /locus_tag="LP468_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2081651.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(13051..13554)
                     /locus_tag="LP468_002144"
     CDS             complement(13051..13554)
                     /locus_tag="LP468_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL2081652.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13567..13728)
                     /locus_tag="LP468_002145"
     CDS             complement(13567..13728)
                     /locus_tag="LP468_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081653.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4227 a         2711 c         2513 g         4292 t
ORIGIN      
        1 gaggtaaatc aaatgaaaaa atctttaaaa cttgcatcag cagttatatt aatgtcccaa
       61 ctccttatag caacaccttt ccatgtgttg gcaagcgaaa attcaacata caaaattgca
      121 aaagaaagaa ccgagacgac tgaaatgagt aattccgatg taacagcaga gagtagtgaa
      181 cttttgacaa cttcatcaag tgaaagtagt acgacttcaa atgccgagtc ttcaacaact
      241 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc atcaagtgaa
      301 agtagtacga cttcaaatgc cgagtcttca acaacttcgt caagtgaaag tagtacgatt
      361 tcaagtaccg aatcttcaac aacttcaagt agtacaagtg aaataacttc ttcgaaagtg
      421 acaaaaccaa accatataga atcttcaaaa aaggaagcgc caaaaacgga aggacaaaca
      481 aaaacttttt cgacaccaca gcaaatagaa tcaacagaat ctttccaatc acaaccaata
      541 ctatctggta atgaagaaat tcattttgac aaaaatgaat ctgtagaaaa ttttattatg
      601 aaaattggtg agtctgcgag aaaaattggt cagaaatatg atttatatgc ttctgttatg
      661 attgcacaag cgatcttaga atctgccagt ggtcaaagcc agttagctca ggcaccgaat
      721 tacaatttat ttgggataaa aggaacttat aatggaaact ttgtcattat ggtaacaaac
      781 gaagatttgg gtaatggaac gctttatacg acccaatcaa aatttagagt gtatgaaaac
      841 tatgaggaaa gctttgaaga ttatgccaaa ttattaacta agggaattag tggaaataaa
      901 gatttttatg caggagcatt aaaagctaat agtaaaacat atcgagaagc aactaaattc
      961 cttacaggac ggtatgcaac agatacacaa tactatttga agctaaatga attaattaaa
     1021 acctacgatt taaccaacta tgataaagaa gttaaaggtc cacaaatgag taagactgga
     1081 taccaagtgc ctattcataa ttattcaata accagtttgt ttggaaatcg tggaaatgaa
     1141 tttcaccgag gacttgatat ggcagctaca cagggtgagc cgattcatgc agttaaagct
     1201 ggtaaggttg ttaaagcaga gtttcactac tcttggggaa attacgtggt gatacaacac
     1261 gaagatggat caaccgcgtt atatgctcac cagcaacaat acctagtaaa aactggagat
     1321 aatgttttgc aaggacaaat aattggctat gtaggaagta ctgggaatag tactggccca
     1381 caccttcatt tggaaatttg caaagatagt agtctttctc agagcatgtt agttgatccg
     1441 aaaaccttat tattcggaga ctaaaaaagg taatcaatct gacaaagtaa caagaaaatg
     1501 gttggattct tagacctttg atcaggatat tgagactgga attgatatct cgattacgat
     1561 gggtttgaca aataaaacaa gtccattatc gaatatcgag tgtattattg ccgtctttat
     1621 gctcatattt tgagcaggtt tcactagatg aaaacaattt atctatcttg aggatttcgt
     1681 gtacgtatcg ttcagtcttg tattgtaaat tagtcataaa atcagactaa gaaaaattgg
     1741 aaatattttt ttctgattta ttaaaagtta attgaaatta tatggtactt ctttcttggg
     1801 agggtaggtg cagtgaagga aagatatggt caccttactg ttgttgagga gattactcat
     1861 aatggatata aaaaatatcg ttgcctatgt gactgtggga atgaaacgat tgtatatcga
     1921 tcaaacttac taacaggtag aaccaaaagt tgtggatgtg gaaattataa aaataggcat
     1981 aaatataaaa atttgacaaa taaaactttt ggtaagttag ttgcaatcaa gccaactaaa
     2041 ctgcgaagtg aaggaactgt tgtttgggaa tgtcaatgtc tgtgtgggag aaaaaagtta
     2101 gtatcggcaa agcgacttct aaaaggtgat gtaaaaagct gtggatgttt gaaatcaaaa
     2161 aagcatcaca ttgaaaataa aaaattcgga ttacttactg caaagtatcc tttggacaat
     2221 aactgttcat ggaaaacaaa atgggtttgt cattgtgagt gtggcagtat gtgtgagata
     2281 agttatagta acttattttt tggacatact caaagttgtg gatgtttaaa aaggcaagaa
     2341 acaaggacat gtgttgaagg gacagtaata gagtgtctaa cgtcaaaatt accgaaaaat
     2401 aatacaagtg gtgttaaggg agtttatcgt tctaaagaga aatagattgc gtatataact
     2461 ttaaaaaaaa agaggtacta tttaggatcg tatgattcta ttaagagtgc agctcaagct
     2521 agaaaagatg ctgaaaataa attgtttcaa cctttgattg acaaatatcg aggtaatcat
     2581 taattattgt ggataataat taacagtgat atataaacat ctataatata ttattcatac
     2641 tattgatatt tagtataatc ctatggaatt gaatatcata gcaatgtatt tgaaaagcaa
     2701 attggaaaac aaataggtgc aacaccataa atatgaaaaa attgggaaaa agtagaatgg
     2761 aaatttgctt acgtctcacg agatagctca cactattaat ctgaagaaca atgaagtcga
     2821 cttttagaaa ttgctagaag aaagtaaagc gaattatcac tagttactat agagtaagtt
     2881 caaataaagc atctccaact tacatggtta catgaggata tcaaatcgaa attactcaag
     2941 cttcctatgg ctagagtcgc gagaagttgt tgggcagtag acataggtta tattgttctt
     3001 agctacacga tcattagaaa ggaaatccta ttatgtatag ttatcaagaa gatgcaaaag
     3061 tccaaaaaaa tcgctggtgg attttgattg ctatatctat gtttaccttc atgtccacat
     3121 tggatggcag tattgtcaat attgcactac ctaccatctc agatgatatg ggcataccaa
     3181 tgaatcaagc ggaatgggta gtgtccgttt atctgatgat tgtctgttct tgtttgttgc
     3241 tgtttggtaa aattggcgat agccgtggga aaatcaaagt atttcggatt ggtacgctga
     3301 tctttgtctt gggatcgctg ttgtgtgggt tcaatcattc gctaggtatt ttattgttcg
     3361 cacgggtggt acaagccatt ggtgctagta tgactatggc tacaaatgcc ggaatcatca
     3421 cggaagtctt tcccatacat gaacgtggtc gggcattggg agcaataggt gcgtttgttt
     3481 cattaggctc gattgctgga ccaggtcttg gcggcttgat tttgtcccaa ttttcttggg
     3541 cgtacatttt ttggatcaat gtaccggtgg gaatcgtaac gatgttgatt gctgaaaaat
     3601 tcttaccaaa agatatcacc atgagcggcc atacaatcga tggagggggc tttgctgcca
     3661 ttgcggctac gattatcagc ttttttggag caatcttttt ggggcaagaa agtggctttt
     3721 tccatccagt cccccttgta ctgttcgtaa tttcagtgat tgcctttgtc agctttttaa
     3781 aagttgaaaa gaaagcagcc tctccattga tttctttcgg tatttttaag aacaagattt
     3841 ttaccatgag cttgattaca gccttgttga ttttttcttc caacttcttt gtcaatgtag
     3901 tgattccttt ttatctgcaa aatgctcgcg ggttgagtcc tagctatgct gggctgttga
     3961 tgatggtctt tcctttgatg atggtcgtcg gggcgccttt aagcggctac ctgaccgacc
     4021 gggttggccc ggagattttg gtattagtag gcttgggctt attgtcggta acccaggtca
     4081 tgtatatgtt tttgtcagtg gactctcctt tgtggctata cattgtcgct actgccatca
     4141 tgggtgccgg caatgccttg ttccagtccc ccaataatac gatggttatg agctcggtca
     4201 ctatcgaaaa cttgggactg gcaggctcga tgaattcctt tgcccgaaat ttggggatgg
     4261 tcagcgggat ttcgctttct acgacggtct tatatcaagc gatgtctgct aagatgggcc
     4321 agcaagtaac taactatatc gcaaatcggc cggatgtctt tttatatgga atgaagatta
     4381 cctttttagg cagctttgtt ttgtgttttg ttgccttttt cctgactatc tggcgtatca
     4441 aaaaacaagg aggtattcag aaaaatgtct gaaaaaacca ctgttgaaga atttttggag
     4501 gcctgcgtat gggtgagtgg gatttccatg gatgatggaa gatgaagtga acttctaaaa
     4561 gccgaaaaac tcaagtatta tcttcaaaat actagtgctc aatgagatgc ttgatttgat
     4621 cacaagaaga ctgcgaaagc cgctggcaac cgcaagctag gtatcccacc gatggactac
     4681 gttttagagg ctactggtta tgaatacgga gccaacgctc tcatctgcat aagaatacat
     4741 cacccagatt atgtaaagat tttcgatact tctgtcaaaa aatcattaag atagataaat
     4801 gatttccgtc tagtcaaatt ggttcagaat gtagacacac agatggtaag aagtcactca
     4861 caattcgaga atggacttgt cctatttgcc gtatacatca taatcgaaac gtcaacgata
     4921 gtatcaatat tttgaccaag ggctatgaat acaagcattg ccttagaaaa catcaagaac
     4981 cttaggaaca acggggatag cttggttaat aagagatacc gctgtttagg cttgcaagta
     5041 tactctttta tcaagaattc cgtggcttta gtcatgagag gcttaatact atgaaaattt
     5101 tctttagcat ttttgattta ggttcctttt ctaattataa taagatgacc actacagtaa
     5161 cctactgaaa tatataaaca gccactgtag taccattttc aaagtagtct atgagaggag
     5221 aatcttcatt cttatgaacg ctggaattgc ggatatgaat ttaataaaaa aaacccttaa
     5281 tgattttact tccaattcaa tatcaaaagg tactggtatc aatttaagca caataaaaaa
     5341 gctgaaaagt ggtgaaagat cagtggaaaa gctgaatctt ttagatgcta taaaaataac
     5401 ggaatttgct atgaaaaatg gaaaagctga gattgaaata tggagataat tatcgtctag
     5461 tgaattactt gccacttagc tgaatttaac gatccttggt gcttgaaggg ggagattctt
     5521 gggaatagag catacttgca agcctatgtc tttactaaca acgatatctc ttattaacca
     5581 agctatcccc gtagttctaa ggcttttact tttatctaag caataatcgt attcaaagga
     5641 aatttttgac ccttagaaag tctcatttta tcagacgtga gcttaggcat tgctgaattt
     5701 tgttaattcg gttttaggtt gtgctttgag cataatatga aagtattctt tatcacgatt
     5761 tcattcatct aaggtaatgt gatgtgattc tgaaattctt tcaaaggcag tttttgcata
     5821 agctgacatt acatcatcaa tgacatgttt acaatgtttc actactaaaa taagggggta
     5881 accaagaaga aaaactgaat gattatttgt atctaattcc atggtatatc aaccatttcc
     5941 tatatagact gattatgaca tggattaaaa taaaaaggca ctatgtctta attgtcggtt
     6001 ttcgagttac cgaatggcat tcatcaccca cctatagagg atgggcgact tctgcctgaa
     6061 ataagttaca ctacttataa cttctaataa aattagattg agtcattatt atttaacatc
     6121 aacgattttc cagtttccat ttttttgtaa tactaatttg tactgaaagt agctagtggt
     6181 ttttgataca ttatcaaggt attttatctt tgtactcact agaaaatttt ttccgttttg
     6241 tagataaact ggattctcta actccgaaaa ctttaagtca atattgattg gtcgcatcgc
     6301 accattttca acataatact ccaattcttt ttcagaagct gatggataaa gtttaaaaaa
     6361 tgtttctaaa aaatcggtga tttcttccgt tgttttggca tcaatttctg aatcgttttc
     6421 tacttgtttt gcttcatatt ttgccttgtc tggctttcca atcattgttg gcaaactagt
     6481 tactaaatga ttcctgtttt catcttcaaa gattgtcact cgatatgcag aagaaattga
     6541 ttgcgtcttt tttccctctg taatatgttg ctccactaaa aatgaaacga caaattcttc
     6601 cgagtgtttt tcaacatcta gaatttttac agattgaact tcggaactcg tgggaatatc
     6661 tgctcgaacc atatcttgga ttaaagcgag accgttttct gtaaggtact gttcgagatt
     6721 actcattctc ttttcaattg cttctttgtt atttttccat gaaaaatatt ctttcgcaaa
     6781 atcctctgta aaactttcaa cgccagaagt attcactacc ttctctttta taaccacttt
     6841 ttcatgagtt gtatgttgat caatggcggt gaaattttta taaacgccaa aagcaagact
     6901 acaagacaat aaaagccaaa gggcaagcac catttttcga tgcttaccca cggatacaac
     6961 tcgttctttt ttcttttttg ggctcttttc cttttgattc cgttcaattt ttatcttcat
     7021 tctttttcct cttttctctt atttgtatcg gccagctccg ataagatgct gccgccaata
     7081 gttttccgtt agattcgtcc accccactgg atctcctgca tgaaacatgc gattctcccc
     7141 tgcgtaaatg cccacatggg tcacataagt accggcatca taggttgaat gaaagaaaac
     7201 taaatcacct ggtttggcat cttttagatc aatatgagtc atggcatcat attgatcctg
     7261 agccacccga ggaagtttca ggtcaacttt ggcataacac cattgggtca agccactaca
     7321 atcaaacccc gtttctggac ttgagccacc aaacacatag gccgttcctt catacttaaa
     7381 tgcctcatca aaaatttctt ggactatttt gtcatcaaac tgggttgtag ttaggtattg
     7441 cttcactaat aaacagtaaa acatattgcc ataattatac cgccacccac cattttcctt
     7501 aatcgcgatt gggttggggt aatcgacttt ttgaccacct gatttttcct ttgaaaaaga
     7561 ttcagctaaa gcaaaactat gcttcttccc gtttttcccg acatgatcta gatacccgcc
     7621 accatagtta taggcctgaa taatactatc ttgatcacac cctagttctt tggaacgctt
     7681 aaccaaagac gcaaaataga gacagccttg tttgatggat gcctcggtac ttaatgaatt
     7741 aggtggtaat ccggctgact cagaactttg cataacgtct tccattgtgc caccagattc
     7801 cacttgaata atcgccaaaa gaattggaat atactctgtt atatccgatt ctttggcata
     7861 cttttccacc attgcacggt gtttcaatac ttcttctgag acactagttc cgccaggaga
     7921 agtgccagaa ctaccatttc cctcactgtc ttcaccaaac aacaaaccca cacacatcaa
     7981 aatacccata aaagagatgg tcagaaaagt taatgaaata acacccactt tcttcaagtt
     8041 cattttttct cacctgacct tgattttgga cgatggttca ttcttttttg tactttttga
     8101 ttggtctgct ttggcagagt ggacctctgt ttcacttgtt ggaaagaatt tttcttactt
     8161 gctgattggc ttttcccttt tgaaatgatt tcttgactag ttagttttcg tttgatttcg
     8221 ggattcagat ttgctctcac aatccgcttt ggtgcttctt ttttcagcat catatctttc
     8281 tgaggttgag ctgctttatc tattggaata ttcgcccttc tttttccctg acgatttgtt
     8341 gcttcactca gtatcttgcg tttttcgtcc attttcgcat ttcttcgttg tcgttgtttt
     8401 tctcgcaaat ccactcgatc cgctttttct tggaacagtc cgcgcttgaa ttcttctggt
     8461 gcttttttcg acttttcgat tcctttatgg agattgtatt tcaaattcgt tggcgtattc
     8521 cttacctgat cctttacttg tttagtctta tctttcacca aagcttgggt atccaaaact
     8581 ttgccgattt ttctcccagc caaattcatt cgggattgtt tcttattatt tgaaactgga
     8641 ttctccttag ttaagtcaga tagtatttcg tgatcgttcg gtaatcgtga attctttcgt
     8701 agagaagaac cggatggctt aaatttggat tttgattgtt cctttgccaa cttatttccg
     8761 actgctgcac caccaccaaa agccaaagct cgtcccacat ttcgattgag ttgccgcaat
     8821 tttcgattca ttaacatttg cggttttcgc atgacgcgtc ttcccattga ctggctatca
     8881 ttactctgga ggttgaacat actcataatg tcgcccaatt tgaaatagat accggcaaag
     8941 gtcacaattt gcagaaaagc aaccatgaaa aatggatagg ttgccgaaat attgaaaaac
     9001 atcgtggaga tgctaaatgc agtcgtaatc accaaagtaa cacccgctcg catcataatc
     9061 gtattgaata aacgaataat cgccttcttt cctaaacttt cataagtcgg caacatggac
     9121 aataagaaac taattggcag aaacatcgca aagataatga agagaatttg cgagaacaac
     9181 ataatccctg ttagaagaaa aacaaagaag gaaatgccaa tattgaacaa taccaaaaag
     9241 accacggtcc ctaaacggtt catggtcttg gtaatactga gattcgcatt gtcattgtct
     9301 tcaatctctg ccttgaccgc ttcttcccga tctttgcctt tgttttcatc tggactcaca
     9361 gatagaatct tgttgacccg gtcttcacca atttcttcta tgttggaatc atcaaattgc
     9421 agtagtaacc aaggttgttg gacttgaatc gaaaacaaac tatcccgaat caaatccaca
     9481 ctatcttttc cttggctttc tgaattgggt acaacgatct cggttccaag ggtaagggcc
     9541 gcttcactaa catctgagct aaagtcattg atttttgtga tataggtagg cgcataagca
     9601 atgaacgaac ccgatagtag aaaaatcatc acaaaattaa tcacggctcg aactgctttc
     9661 gtggtttctc gttttaataa tccggtatac gccacataca cccccagagc taaaatcatc
     9721 aataatagaa acccaaaata aaatccggag gtctggagtc cattttcagt aataccagcc
     9781 aatgtttgga tattctttcc aatactttca gccgtatccg aaatgaaatc taatttgtaa
     9841 gcctcttgaa ccacataacc cgtggcgttc gacaaataca aactcaccgt ccaaatgaaa
     9901 ttagtaatgg cataaagacc atacatcacg cttttcccta agccatcacc ccaattccaa
     9961 ggcaaccaat cccaagagct atccacaaag aaatctagtt gatagttgtt cagtgaatat
    10021 ttggaatata gatttcctgc ttcaactgta tcatcaacta gccctgtcgc ctcggctacc
    10081 gtaccaacta aactcaatag aactatcaga gtgagtatgc taataaaaac gattcccaca
    10141 atccgaaaaa gtttcttttt catcccctca ctccattctc tcttgaacag gtggacgggt
    10201 atcaaaggca tggaagagtt cttcaaagac tggatgtacc tgaaccacgc ctacccgacc
    10261 atacaaatcc tgcatcaagc attggccatt ttccaaatct cgtaggcgtt tttgattgct
    10321 ttcatcttct cgatccaagc caaagaattc caaggttttc ttgatttcat gaatatcggt
    10381 actgcgaaac gcaaacttca acccgatatt attcttcaag cgttcatcca gtaaatcatc
    10441 actattttgc gtgacaaagt aaaccccggc attcatagcc cgcccagcac gaacgagctt
    10501 attcgataat gttttccctt gcgctacttg aagaaaactc cacgcctcat ctaagtctac
    10561 aattttgaag atttctcgat tactatggat aaagtccaag gcaaaagtgg aaatgacgat
    10621 tagcatggaa acactaagca attccatggt ggtatattct tcaaaagtgg tttctgcatc
    10681 tggtaaaacc aaatccgcta cttgaatgat atttaactgc ctatctaaac taatcgactg
    10741 ggtaatcgaa ccatctgaga aaagcaaatg ggcaaaatca taatcggtaa aggactcgat
    10801 gtgatccgcg atattttccg caactggtga gccttctttt cgaagctcat taattacttg
    10861 taataatccc cgttgattgc tttgggtaac cgtccgaatg gccttacgca acactggaaa
    10921 cttctcccca tctcgactag aaattcctgt taaaaaggtc agaatatcaa ttgctagact
    10981 ttcagaatcc ttctttttct ccataatcac ataaggatca agtaatcctt gattttttgg
    11041 cttactagtt aagttgagaa tattgatttc atccgcaatt tctggcaagg tttctttcca
    11101 gccaccccgt tccccttttg gatcgacaat cacagcttgt ccaccaaaaa ggacggcgta
    11161 ataaactaag agattgttac taaaggactt tccgccaccg agtgaaccga ggaatgccgc
    11221 tgctagcgca ttggtaactg aatccttgac cccttgtgag gccaatgccg gtttcaggta
    11281 aacattgcgc cccgtatcta cgttataacc aaagtaaatg ccttccaact cccctaacat
    11341 ctgagtggcg ccaaaaccaa gtccggcgag aaaatcagac gtaacatact ggatataatc
    11401 attcatgtat cgcttactag aaggtaagaa ttcttcatgt agccccatca tatcgccaaa
    11461 aggccggact agttttacat tggtatcatc ataaaaatct agcacttcat cacaccggcg
    11521 ctttagttca tctactgatt cggcacttac tcgaaccaca tagctcagtt tgtacatgga
    11581 ttctttggac tgatccaagg tagtttccaa ttcatctacg gaatccaatg catctaagac
    11641 attggaattt gtttcattgt cagattgata ggcatggttg tccaagtctt ttaattcctt
    11701 tttcttattg cgaacggtag caagtgcctt tttgttcgtc acaatctcca cattcatact
    11761 agtgtcaatt gggaatgtaa attgttgttg ctggtaatag aaaagttctg aggagggaaa
    11821 ctccatttcc cccacaattg tattaattgt taagtacgct acatatgatt catgattctc
    11881 atgttccatg cataagtacc ggggcttttc ttcaatcaaa caacgactgg gacgtaataa
    11941 gtcgtaacgt ttcaccaaag tttccgactt cagctttttc tttggtagct gaaattcata
    12001 ttcttcaaat ggtgtaccct tttcgccata gatatgttca atcaaataca tcagatcact
    12061 cggtgtgact cgtctgactt taaatcttcg agccaattta ctttccatta gtttttcaag
    12121 cttggtatat cggcgaattt cttcattgga taaggaaaca aaatcgccca tcaaatgatg
    12181 attcactcca tagacaaatt cttgaaagcc ggagaagaaa gatttcttga gattctttag
    12241 attgacctct tcatctgtcg caatcagttt gaagccaata aaaaagcgat aatcaatctg
    12301 actatcgcca atcatggata ctaatgcctc tgtctgtaaa tcaattcgtt gtttcgctac
    12361 ttctgttaat cgcccggtaa tttccttttt tgatcgttct tgcgtggcac gaatactact
    12421 ttctgtggca atttgtaagg catgaatctt gccttcacga ttttgcgcaa tcaattgacg
    12481 aaagttatcg tggacttgat atttctgttc aggtgacaaa aaggagtaat tgtaaggtat
    12541 taactcatag taggcaaaac attctccctc ttgattaaag acaagattat tttcaatata
    12601 cttaatcggg tacatagttc acactcctta ccagagtaat gggttcgtcc catcgtttct
    12661 tctgttcttt gactttcttt cctgcgaaag tgaccttaaa tcgtaagtga tagctaataa
    12721 aagatcgtaa aaatcccaat ggtttcttac cgtcaaacgt tttttgcgac atgaaccaag
    12781 taactgccac cggtatacct aagtatttta aaaaggcccc ctctatcata gatagtggag
    12841 gcacatgggc aaatacgatg acaaacagca aggataaaac aaaccaagcc atctggttaa
    12901 aagtcacagg aaaaggcagt tgaaagtcat taattgcata aatgaccttt tcaactgccc
    12961 aaatactggt gtagcttttt attttcttca tcaaatcatt cctttaaaaa gaaggatagt
    13021 ttagaaatca actacccttc aataattttg ttaatatgga tactcaaaaa cacctcgact
    13081 cgttaccaaa taattgcctc caatctccaa gtctctacca cacgcatcaa aatcaatata
    13141 cgtcttcaag tgttctggta cttctccaaa atcaccagct tctacaatca agaaatatgc
    13201 tacatcactc atatcatcgc aatctggata atagataata tcatccacat gctctaccat
    13261 ctcctcaaaa gaattgaaga aagcatgttg aatctcagaa gcaacttcac caactggcgt
    13321 tccttcaagt tcctccgcta agccacacaa ccgattaatt tcctcaattg gcgtatactc
    13381 atcaatctca aagggaagtt cataatcatg aattgcatat tcctcgtatt cgtcatttaa
    13441 cccaattcgt tctttcactt catcaaaatc gacaggtggg gtaaaccacg cccccaccaa
    13501 ttcaccttcg ttatatttcc cgaggttcgc aatataaaca cgcatctgtt ccatcgtgct
    13561 tcccccttac gcaccgacaa ttcggttaaa caaactgagt aagacatcct tcaccccaga
    13621 agcattaaag accaatccga ccgcaatcaa agcaatcacc aaaaagccaa tcagtttgga
    13681 aaactcccgc ttaaatccta aaaacaaacc aatgaccaca attgccagta agactaagga
    13741 ttg
//
LOCUS       DAFEML010000062        13429 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFEML010000062
VERSION     DAFEML010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.063"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..914)
                     /locus_tag="LP468_002146"
     CDS             complement(<1..914)
                     /locus_tag="LP468_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL2081654.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="LP468_002147"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="LP468_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL2081655.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="LP468_002148"
     CDS             2006..2176
                     /locus_tag="LP468_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081656.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="LP468_002149"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="LP468_002149"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL2081657.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="LP468_002150"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="LP468_002150"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL2081658.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="LP468_002151"
     CDS             4440..5321
                     /locus_tag="LP468_002151"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL2081659.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="LP468_002152"
     CDS             5318..6034
                     /locus_tag="LP468_002152"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL2081660.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="LP468_002153"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="LP468_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL2081661.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="LP468_002154"
     CDS             6751..7752
                     /locus_tag="LP468_002154"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL2081662.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="LP468_002155"
     CDS             7749..9110
                     /locus_tag="LP468_002155"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL2081663.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="LP468_002156"
     CDS             9070..10221
                     /locus_tag="LP468_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL2081664.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="LP468_002157"
     CDS             10196..11365
                     /locus_tag="LP468_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2081665.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="LP468_002158"
     CDS             11540..12919
                     /locus_tag="LP468_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2081666.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="LP468_002159"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="LP468_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4487 a         2340 c         2921 g         3681 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatatgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caattcttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa accagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgagaaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DAFEML010000063        13146 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFEML010000063
VERSION     DAFEML010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.065"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="LP468_002160"
     tRNA            complement(77..149)
                     /locus_tag="LP468_002160"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LP468_002161"
     CDS             530..1099
                     /locus_tag="LP468_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL2081667.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LP468_002162"
     CDS             1086..1946
                     /locus_tag="LP468_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2081668.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LP468_002163"
     CDS             2136..2840
                     /locus_tag="LP468_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081669.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LP468_002164"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LP468_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL2081670.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LP468_002165"
     CDS             4677..5993
                     /locus_tag="LP468_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081671.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LP468_002166"
     CDS             5994..6863
                     /locus_tag="LP468_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL2081672.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LP468_002167"
     CDS             6918..7727
                     /locus_tag="LP468_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2081673.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LP468_002168"
     CDS             complement(7830..8459)
                     /locus_tag="LP468_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL2081674.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LP468_002169"
     CDS             8629..9921
                     /locus_tag="LP468_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081675.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LP468_002170"
     CDS             complement(9997..10659)
                     /locus_tag="LP468_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2081676.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LP468_002171"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LP468_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL2081677.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LP468_002172"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LP468_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL2081678.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattc
//
LOCUS       DAFEML010000064        12732 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFEML010000064
VERSION     DAFEML010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.066"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP468_002173"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP468_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2081679.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="LP468_002174"
     CDS             complement(322..891)
                     /locus_tag="LP468_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL2081680.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="LP468_002175"
     CDS             1077..1979
                     /locus_tag="LP468_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2081681.1"
                     /translation="MNTKDIKYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP468_002176"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP468_002176"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL2081682.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP468_002177"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP468_002177"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL2081683.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP468_002178"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP468_002178"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL2081684.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="LP468_002179"
     CDS             8547..8732
                     /locus_tag="LP468_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL2081685.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="LP468_002180"
     CDS             complement(8794..9990)
                     /locus_tag="LP468_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2081686.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="LP468_002181"
     CDS             complement(10160..11596)
                     /locus_tag="LP468_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2081687.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="LP468_002182"
     CDS             11889..12698
                     /locus_tag="LP468_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2081688.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2672 c         2248 g         4010 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agctgctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcaaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt ga
//
LOCUS       DAFEML010000065        12393 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFEML010000065
VERSION     DAFEML010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.067"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            22..426
                     /gene="tnpA"
                     /locus_tag="LP468_002183"
     CDS             22..426
                     /gene="tnpA"
                     /locus_tag="LP468_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBL2081689.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            443..1591
                     /locus_tag="LP468_002184"
     CDS             443..1591
                     /locus_tag="LP468_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2081690.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1746..1937)
                     /locus_tag="LP468_002185"
                     /pseudo
     CDS             complement(1746..1937)
                     /locus_tag="LP468_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            2070..2444
                     /locus_tag="LP468_002186"
     CDS             2070..2444
                     /locus_tag="LP468_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HBL2081691.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
     gene            2498..2902
                     /locus_tag="LP468_002187"
                     /pseudo
     CDS             2498..2902
                     /locus_tag="LP468_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2954..4126)
                     /locus_tag="LP468_002188"
     CDS             complement(2954..4126)
                     /locus_tag="LP468_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBL2081692.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            4229..5956
                     /locus_tag="LP468_002189"
                     /pseudo
     CDS             4229..5956
                     /locus_tag="LP468_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5953..6573
                     /locus_tag="LP468_002190"
     CDS             5953..6573
                     /locus_tag="LP468_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081693.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            6687..6824
                     /locus_tag="LP468_002191"
     CDS             6687..6824
                     /locus_tag="LP468_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081694.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            7266..7646
                     /locus_tag="LP468_002192"
     CDS             7266..7646
                     /locus_tag="LP468_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL2081695.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            7628..8542
                     /locus_tag="LP468_002193"
     CDS             7628..8542
                     /locus_tag="LP468_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2081696.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            8782..9471
                     /locus_tag="LP468_002194"
     CDS             8782..9471
                     /locus_tag="LP468_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081697.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(9591..9677)
                     /locus_tag="LP468_002195"
     CDS             complement(9591..9677)
                     /locus_tag="LP468_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2081698.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            10322..11059
                     /locus_tag="LP468_002196"
     CDS             10322..11059
                     /locus_tag="LP468_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2081699.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            11087..11626
                     /locus_tag="LP468_002197"
     CDS             11087..11626
                     /locus_tag="LP468_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2081700.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            11642..11812
                     /locus_tag="LP468_002198"
     CDS             11642..11812
                     /locus_tag="LP468_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081701.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
BASE COUNT         4599 a         1930 c         2004 g         3860 t
ORIGIN      
        1 caagaaatga gttgatataa catggaatta gatacaaata atcattcagt atttcttctt
       61 tattaccacc ttgttttagt aacgaaatat cgtagacaag tgattgatga tgaaatatct
      121 gattatgcca aaactacttt tgaaagaatt tcagaatcgt atcacattac tttagtggag
      181 tggaatcatg ataaagacca cgttcatatt atgttcaaag ctcaacctaa aacagaattg
      241 acaaaattca tcaatgccta taaaagtgcc agctcaagat tgataaaacg tgactttcca
      301 agagtcaaac aatttctttg gaaagaaatg ttctggtcta aaagtttttg tcttctgaca
      361 actggtggcg caccaattga tgtgattaag aagtatatcc aaaatcaagg aaacaatcat
      421 aaatagaaag taggtgaact ttatggaaca actaaaagca tacaaattca gaatctatcc
      481 aacagaggaa caagaaatct tctttgccaa atcttttggt tgtgtccgta aggtctacaa
      541 tctaatgctt gatgaccgaa aaaaggcgta tgaagaagtt aaaaatgatt cttctaaaaa
      601 aatgactttt ccgacaccag ctaaatacaa gaaagaattt ccgtttttga aagaaattga
      661 tagccttgct ttagccaatg cccaacttaa tttagataaa gcatacaaga atttttttcg
      721 ggataaatcc gttggatttc cacgtttcaa aagtaagaaa aatcctgttc agagttatac
      781 aacgaataat caaaatggta cagttgcttt gattgatagt aaattcatca aagttcctaa
      841 attgaagtca ttagtaagaa ttaagcttca tagacaacca aaagggatta tcaaatctgc
      901 tacaatatca cgtcattcta gcggtaaata ctatatttct ttgttgtgta aagaagaaat
      961 tatcgaatta cctaaaacta attccacaat tggtattgac ttaggtatta tggactttgc
     1021 gattctttct gatggacaaa aaattgataa taataaattc acgtccaaaa tggaaaagaa
     1081 actaaagcgt gaacaacgca aattgtctag gcgtgcttta ttggctaaaa ataaaggtac
     1141 caatctattt gaagctaaaa attatcaaaa acaaaaacgc aaagtagcta gattgcatga
     1201 aaaagtaatg aatcaacgta ctgattttct gaataagttg agtacagaaa tgatcaaaaa
     1261 tcacgatatt atctgtattg aagacttaaa cacaaaaggt atgttgcgaa atcataaatt
     1321 agctaaaagt atttctgatg tttcttggtc aaagtttgtg actaaattac aatacaaggc
     1381 tgactggtat ggacgaaaaa tcatcaaagt agataaatgg tttccgtcta gtcagatttg
     1441 ttcagagtgc ggacataaag atggcaagaa atctcttgaa attcgagaat ggacttgtcc
     1501 tgtttgtcat actcatcatg atcgtgatat caatgctagt atcaatattc tgaccgaagg
     1561 tctaagacta cattctatgg gattggctta gatccaatca tcaagaaccg taggaactac
     1621 ggggatagct tggtaaataa gagacaccgc tgttagtaaa gaaatacgct atcaagtatg
     1681 ctctattccc aagaagctcc cacttcaagc gttaagaacc gtcaggttta gctaagtggt
     1741 gagtagttca caatagaatt tatgttagta ctataaaatt cacaaatttt ttttagtgtc
     1801 tctatatctg gtgttgtttt gttattttcc cactttgaaa tagtttgacg tgtaacgtta
     1861 aattttcttg ccacatattc ttgagtatac ccttttttca ctcttaattc tcttagctta
     1921 gatcctaaat cctccatttt ttctcctatg taaacgatta tttacataaa attttatcat
     1981 aaaaatacta acgcgccaaa aaagttcttt attttataaa acacactaaa ataaaataat
     2041 tctagtaaaa aagataggag aaataagtta tgaaaaaatt tttatgtctt tctgctttaa
     2101 tgggtgtctt attaactagt ggaggaatag ctagtgccac agaagcttta aatctagatg
     2161 tacccgaaga ccataccgcc atttacggag gaggaatgga agctacagaa gaaggatttt
     2221 cttctagtaa attgagatat gctgctggcg gcggggattt caactgtggg gttaatggat
     2281 ttaaagttta tgcaaattac taccatgcta gagctaaaca tagtgcaaca gctaaaaatg
     2341 gacgaggcgg tcaagtacga tcagttcaga aagctggagt aagagcttat gcaacatgca
     2401 atgccacact tactggaaat actggttggt ggaatgttta ttaaaaaaga gagtttaaac
     2461 tctctttttt atttacattt gaaaggaaat tcaaaatatg ttaaaaaaaa taaacgctgt
     2521 tttatcactt tttgtctgca ttacaatact atttttttct actaatgtta taaatggtat
     2581 aaagacttct gaagcgctat ataaaaatac cgctgaaatt catatgcaat ataaagatga
     2641 tatggacttt aacagttata taaacgcttt gtatgaaata tctacacaag aaaatattaa
     2701 tatttctcaa tatagtttta ctgctgttaa ccaactaact attcttgcta caaaccctaa
     2761 cgctaacaaa cactggaaat tttctaaaaa aaatatatta gcaagaaacg attctaaagt
     2821 ccattatact aataacaaaa attctaagta ccaattaaaa cttccaaata attttttaaa
     2881 tataaatatt tatccttttt ctcagtcaag tccagactcc tgtgtaaaat gctatacaat
     2941 gtttttacca tttctactta tcaaaattga tgtattttct tgaagaataa atccattcat
     3001 catgtaggtc cataagaacg gctccaatta agcgattggc tgatgtttga ttggggaaga
     3061 tgcgaataat cttttctctt ctgcgtactt cttgattcag tcgttcaatt agattggtac
     3121 tctttagtcg attgtgggaa tttccttgta cggtatattg aaaggcgtct tcgaatccat
     3181 catccaatga tgcgcaagct tttgaatatt ttggttgatc gatataatca tgaatcaatc
     3241 gatttttagc ctcacgcgct aagttaatat ctgtgaactt aaaaattcct ttaacagctt
     3301 ctctgaaaga ttttgaattt tttttaggaa tggtggtaaa gatatttctt aggaagtgaa
     3361 cttggcatct ttgccaactt acgttggtga aggattttct aatggcagag actaatcctt
     3421 tgtgcgcatc agaaataacg agttccgtac cttgtaaacc gcgttctttt aggtattcaa
     3481 aaaatgttgt ccaggtctct tcgctttcgc cactttgaat catgaagccg ataatttcac
     3541 ggtcgccatc tttggttatt ccaatcgcta tatgacagct ttttgagagt actcgatttt
     3601 cttctcgtac ttttatatag agtacatcgg tcattaagta aggataattt ttttctgata
     3661 ataaacgatt ctgccactcg ttaaccatag gttctagctg ttctgttaag ctagaaacga
     3721 aggacttaga gacggattta ccacaaagtt cttccacaat ttttgatact ttacgagttg
     3781 aaacgcctga tacatacatt tccaacattg aagccatgag ggctttttcg tttcgttgat
     3841 aacgttcaaa cactgtgggt gaaaaatggc catcacgtgt tctgggtact tttaattcta
     3901 gcgtgcctac acgtgtcgta aagctgcgct cataatagcc atttcgttga ctttgtcggt
     3961 tttctgttcg ttcatattct tttgcttgaa tatattctgt tcgttgattt tccattagtt
     4021 gattaaatac cgttgttaaa atatttttag aaacgtcatc ctttacagaa tattcaataa
     4081 tgctttgaat ctcttcgctt ttcagtgtaa aatgtacttg ggtcatgtaa aagtcctcct
     4141 gggtatgttt ttgtcgttaa aaacattgta ccgtaaaagg actgttatat ggccttttta
     4201 cttttacaca attatacgga ctttatcttt ttctcatgtg gaaaatattg gattaagtga
     4261 aatattatat gtacaaggaa actcaaacaa attaattcct gtactgaaaa aatatggaac
     4321 acctactatt tccaatatca atcaatcaga tacttttcaa attaatacta atattgttct
     4381 tgttatctgc tatcttagta tatttattgt aattactaca attatatttg ctttttcaaa
     4441 aatgaaagaa atcactctaa aaaaaatgtt aggctataac tcttttgata ctataaaaga
     4501 ttctattaaa gagttaaacc tcttattttg ttctttgatt ataactttca ttttatctat
     4561 ttttttgagc atatattaca gtaacgaaaa ttttttccta tcatttcttc tatgtagtat
     4621 ttttcatttt ataattagtt ttttatttat catagttact ctaagtatct atcatttatc
     4681 tagtataaaa aattatctaa aaaattcacg accacttaag ttaaatcttt gtatattaaa
     4741 tatctgtcta ttcttaagca tgatccttct gttaatagct tctacaaaag taataaatac
     4801 ccataatgaa gccgaaaata attctcttaa atattgggaa agaactacta atttatacaa
     4861 aacaaatatt actaatcaat taaatagaaa caacaccgta gaagaaaata actacttgaa
     4921 aaaagctagt aaatttgttt ataaaataca gaagaattat aaaactttta ttatcgcgcc
     4981 atacaattac gcaactatcc aagagaataa taaagaattt tttattggac aaaaagttta
     5041 tccaaatttt gaagactatg ttagtcaacc tgctggtgca ggaatatgtg ttgatttaaa
     5101 ctatctaaaa tattacaatc ctatttcttt tgaagaatct actgacttaa atttaataaa
     5161 ctctgatcca ctaactactt acattctagt acctaaaaaa tataaagaat atgcaaaaat
     5221 gattgaaaaa aattatttag aagacataca gtttagactt gaggactctc ctcctcaagc
     5281 tccttataaa aatcctaatt tgaaaaattt aaaaataaaa ctaatatttg ttaataataa
     5341 ccaaaagtat tttagtttta ataccttata tggaaaggca aaagataact atacaataac
     5401 tgatcccata gttagagtta ttaatccaga aataacagaa tcattatttt ggggaaatat
     5461 attgactagt gatggtggat tattttttga tcagaaacat acttcaaacc aaaacttttt
     5521 taatcaaatt aatccgtata taaaagaatt taacctagaa aatatcataa atttttctta
     5581 ttctgttttt caagaaactg gtgaattatt atctcaaaaa aaagtaaata aattaaatgc
     5641 atatctacaa tatcttttaa tattaggatt atttataata attaattttc aaatgatttt
     5701 tgttagtttt actataaatt caaaaaaaat agctttaaaa aaaatatttg gatattcacc
     5761 aataagtcaa gttttagatt tatgtttact cccttttaca atagagttat ttgctactat
     5821 gtgttttcaa ttgatatttt caaaaaacac ttacttgtat tttataattt ttatgatctt
     5881 tttaataaat ctaattactt ctattattat ttataaaaaa aatagtttta aatattttaa
     5941 ggagaatatt ttatgatatt atcagttgag aatttcaccc tgtcaattaa taaaaaaaag
     6001 atcaaacaaa attggaactt ttcaatatca gaaaaagatt ttattatagt aacaggaaaa
     6061 agtggtagtg gaaaaactac tctgttaaat aatttaagcc taatagataa acaatatacc
     6121 ggtaacttat tctattttga aaagaaagtt tctaaacatg atatacaacg tctacgaaga
     6181 aatcatatta gctatttatt tcaaaactat gctcttcttg aaaatcaaac agtacaatac
     6241 aatttcgaat tagcaaaaaa gtttaacagt aatatttcca atgatcatat ttataattta
     6301 ttaacagatt tttctttgcc aaaagatatc ttaaaagaaa aaatctttct cttaagcggt
     6361 ggagaacaac aaagaatagc attaattaga aatatgttaa aaccatttga tatattattt
     6421 gcagatgaac ctacaggaaa tttagataaa gaaaactcaa cttttataat gaactttctg
     6481 aaaaatttaa cagaaaaaga aaaaaaagcc gttgtactag taacacatga cttaaatgtt
     6541 ctaaactatg gaactaatat tatagaatta taatttttac ccgtgatgct agctgattta
     6601 aaactagcac cacgggtatt tattttatat tccatctctc ctatcccaaa atttaaataa
     6661 tcacttaata aaaaggaggc acccaagtga ttttattgaa aaaagagtat gaaaaatttt
     6721 atgatagact tatttattct ttgcaattgc caaaaaaatt aaaccgtcaa ttacaaaaga
     6781 cttatgaaac taaatcaact gaagaatggg agagttattg ctagattttt ggtagaagta
     6841 acaaaaagtg gacatattat cataatgact cgccgaaagt ctgataaaaa attggctaaa
     6901 aatattgctg aatgtttaat aaaactatca gttttagcta aatagttagt agtttacaca
     6961 aaaaagcatt tatgtttttt gttgcaaagc aacaatttca tcttcggtga aataagcgaa
     7021 actttacaaa aagtggctag catttgctag ctttttttgt attgtggagc gtggcttttg
     7081 agggggattc aagggggagc ttgcgcccct ttgacaagcg gttatttgca ctaaatacgt
     7141 aggtatttgg ctagcaaata tagagcttgc caaacccttt tagtgagctt tactcattgt
     7201 acctttttag gtacaatggt attgcgaacg atacgtccgt aggacgtact gaaagggtgg
     7261 gacttatgag cgaacaaaat caaaatttgg ctagcaattc ttctaaaaaa tatacctatc
     7321 gatccgagcc aaaacaaatc agttttcgag tgagcgaatc cgaatttgca aagctgaagc
     7381 aatcggctga agctttgcaa atgagtgtgc cggctttcgt gaaagccaag gcacaaaacg
     7441 cgcgtctggt gacaccgaaa gtggcgccag acattgccca ggcaatcgcg cgcgatttag
     7501 ccaaagctgg agggaatatc aatcaaattg ctaagtggtg caatacacac caacatgacg
     7561 ttgcttctgg tgacgctcaa cgtttatccg aaaacctaaa aatcatgcaa aaggagctac
     7621 aaaagatatg gcaacaatta aggtaagccg aaccacttct tgtagtcgtg caattaatta
     7681 cgcagaacca cgagcaacca ttaaaacagg aataaactgt gacgtcgatt atgccaaaag
     7741 tgaaatgaaa caaattcgca tgctgtatgg aaaagacgac cgtgtacagg cacacttatt
     7801 gattcaatct tttcgaccag gagaaattac cgctgaaaaa gctaatcaac taggggcaga
     7861 gtatgcaaaa aaaatagccc ccgatcacca aatagctatt tacacacata cagacaaaga
     7921 ccatattcat aatcacattg tcattaactc cgttaatctg gagactggaa aaaaatttca
     7981 agctcatggt caagcatttc taaacaaatg ttatgaccta aatgacgaga tttgtcttgc
     8041 acataactta ccaatcactg agcgaggaaa gaaaccagaa aaacgaacca tgtctgaaat
     8101 aaaattaaaa gaaaaaaatg aacctgtttg gaaagacgaa attcggattg cgatcgatca
     8161 aacaatgaaa aacaaaaaaa ccagaaccta tgaccaattt tgtaattccc tcaaaacatt
     8221 ggggattcat tgcttcaatc gcgggaaaaa tttcacttac gaattgatcc acaaaaagaa
     8281 aaaagtacga tccaacagac taggaaagga ctacgaaaag gagacgattt tacatgagct
     8341 ggacagacga gaacgaacct ataaccaaca gcgaaccaac gagctacgaa gagctcgagc
     8401 tagcattcgc gaaactgcag aagaagtacg aagagaacaa cgaactctta cgcctgaaca
     8461 accggaaatt agaccggctc gaagaaacca tgaacaacac gttgaaagag gaacagacca
     8521 ccaacaagaa ttatcgctct aaaacgttaa aagacataga aaacgaaata aagaaacaac
     8581 gtgcttttct cgttccttat acgcaagaaa ggatacaaac tacgattgat ttacaagtta
     8641 aaaaactcca tcaagagcta ttagaccagc gaaataagga acagaaaaag gtgcttattc
     8701 aacgatcatt ggattttctt gcccccttat gttgcttagt cctgacactg ttcgcatttt
     8761 ggttagtatg gggaggctaa aatggcattt tatttaccct atctactcat ttttgttagt
     8821 atttcaggaa gtatttggct catctataaa atttttcaaa caagatattc attaaaaggc
     8881 tctaaaattc gatttaagcg atttttcttt cttggctgta tattttcctt gataatcgtt
     8941 tcaagcggct tattcggcgt tttagaggga aataagcgcg tttctagaag tattttatta
     9001 ggaaatgtca ctcaaaagta tgaatcagcg cgtgataaaa agaaaaaaga gcaagcatta
     9061 gcacaaaaaa tggaagagtt taccacttgt tatgaggaaa tgaacgatat ttttgtgaat
     9121 caagaaaaac gtttgacgga taaaaacatg gaaaaactca ctcgtcttta tcaaaacttg
     9181 ccagaaaaac agcaaaaaga ggttcaagac aactatgagc gaaccaaaaa agacgtgcaa
     9241 tatgtaaaag atacaaagat agaagaagcc tgtagtgatc tatttggaga cacaaaccct
     9301 tggtttgcca gtgaagaaga aaaaaaagaa aaacaacaat ctgtcacata tgaacgctat
     9361 gaaatcttac ttcaacaagc aactaacatg caaaatccga caaaaaaaga aaccgcctta
     9421 aactatctaa aaagtgtcaa ggaatggtta gatcagcaac aacaaaattg aatttgattt
     9481 aaaatcatgt taaactgaat gtgcaaatga tcaaacatta gatacacgaa agccccagag
     9541 aggtcggatt ctctggggct tttttcaggt tgatgtcgcc tttattgatt ttacttcttg
     9601 tttcggttat tcaaccaata actgaataaa gagacacaaa ctcctacaag aagggggcaa
     9661 atgaacagtt caaacattag atacacctcc ttccagtcgc aagactgtcg gataggcgac
     9721 aagttattat atcttaaaaa attaaatttg tgtggtgttt ttaagtatca cttgttttag
     9781 ggttgttagg gcttgccctg accgcctgta aggcgcttct cgactagatt aagggaaatt
     9841 aatcaagaat tgtcttagaa cggcttagac aagctttcag agtctcacac ctcctctttg
     9901 aacaacggtt ttagcaaagg agccggaggc gactgcgcag tataatatga gagcatagcg
     9961 atcacacctt tttagcgacc gtagggagca agttttccag tttagaaaaa ttcgcgaacc
    10021 tttttggagg aaaaagtagg agttttttag gcgggaaatt caatgtgctc ttaagatata
    10081 ctgttagata tactgttaga tatactgtta ataataactg ttagggatta gcaaccttat
    10141 gggagagtaa gtattgacat aggtagtggg ggataaattg tcacactatg ggggataaat
    10201 tgtcacacta tgggggataa attgtcacac tatgggggat aaattgtcac actatggggg
    10261 ataaattgtg ttttacatcc tcttatgtct atgataacat aatttattga ggtgattttt
    10321 attgagtaac gatatagttc gatataataa tggattaaat tctgtccctt taagaaaatt
    10381 tacccctata gatatggatt tattttgggg aatatgttct aaaatgaaaa gaaaaggtac
    10441 aaaagaagaa atttttacat ttaaacaaat aaaagaatta attgattaca atataaatgc
    10501 acgtggcgac cgttttgcta atgatttaat aaaaatgtca aaaaaaatca ttactttgtc
    10561 ttttatttat gaagacgaaa aaacatatga acaattaaat ctgtttcaaa aatttaaaat
    10621 cgataaagtg aatgaaacat tattaataaa ggtttctgaa gaatttgaat atatacttaa
    10681 ttcaatcgga actaatttta ctcgtttcga attagaaaat atgacaaact taaagagtag
    10741 ctacgttaaa gagttatatc gccaacttat ggctcataaa gacagaagat ctaaaaaagg
    10801 tcactggttt gtaaaaatag aagattttag agctctatta gcaataccag aaagttatcg
    10861 catgagagat attgataaac aaatttttgc ccaagcgaaa aaagaatttt taaacgttaa
    10921 ttcaactcac cctgctattt ttaaaacttt tgaaatcaaa aaaattaaag cctacaaagg
    10981 aaataagata ggatctctgc aaatttattt tgaagaaaat ataccttcaa ttaccttaga
    11041 taattggtta gagaaataat acctaacaat ttaggaggca attatcatgc aacccaaaga
    11101 aacctttaca ataaaggaat tatctgaatt atttgaaata agtaggcaag caatctctaa
    11161 acatgttgat aaattagacc cgtccttatt agctaaaaat gagcgtggtt ataaggttgt
    11221 attacgttct ggagtattgc aacttgctag caacttaggt aaccaaaggt tactatatag
    11281 gttgcatgag tatgaacaag aaaacgataa aaacgtttat atatcaagca aaaacgtgat
    11341 tgtaaacgag ttgctagata agttgcgtga agaaaatgaa tttttacgag aacaactttc
    11401 cctcaaagag caaaataatt ctaatatgca aaaattactc gaccagcaac aacagctcac
    11461 cctacaggca aatcaacaga tcgaaaaact gcaagaacag ttacaattag cttatacgga
    11521 agaaactcca gaagatgaat caactactat tctttctgaa gaaacagaat cgatagaaaa
    11581 acacacaaaa aagaagaagc aaaaatggtg gcaactttgg aaataactgg agggaacatt
    11641 catgacaaga aaaaatcttc tattcggttc tattttacta ggaattctag gcttcagtcc
    11701 gatgttattg tcagtaatca ataaagggaa taaacatggt gaattgaaat tgaatccaaa
    11761 ttattacaac agtcctaacg aagaattgtt tgtaaaagag acggataaat aataaaaaag
    11821 actgctcttc cgagcagcca gttaaaaaat aatgagtgtt tattcttgaa aaagcacgcg
    11881 cttatgaagc gctaccaaaa atttaccata ttttacaaaa aataacaagt cttaaaaaaa
    11941 tgacagataa aaatgcacaa agaattagat atagataacc gcgaaaaatc aagctttaga
    12001 aagttgcttt tagctagacc aattaaaaat cacaaagtga gcgtctctat ccattggtag
    12061 aggggctact tggcatagtg tacattatgt caactatgca attaaataac taactacttc
    12121 atattagctt aataaaataa tcaaaataac tagggggaaa aacattgtat aaaaaaattt
    12181 ttcatttttt aaataagaat agtaaatata aaaataattt aagatatcta ttactattaa
    12241 tccagataga gcaaaccaag taaatattcc atgtgtaaag ctaaaaaaat tcatttgaat
    12301 caattcaaat aaacctaata tagtaacaaa tatattaaaa ataatagctg tcaataccag
    12361 taaattattt tttttatttt ttgaattatc ttc
//
LOCUS       DAFEML010000066        12260 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFEML010000066
VERSION     DAFEML010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.068"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..555)
                     /locus_tag="LP468_002199"
     CDS             complement(<1..555)
                     /locus_tag="LP468_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL2081702.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(571..1050)
                     /locus_tag="LP468_002200"
     CDS             complement(571..1050)
                     /locus_tag="LP468_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL2081703.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1056..2080)
                     /locus_tag="LP468_002201"
                     /pseudo
     CDS             complement(1056..2080)
                     /locus_tag="LP468_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2097..3203)
                     /locus_tag="LP468_002202"
     CDS             complement(2097..3203)
                     /locus_tag="LP468_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2081704.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3432..6029)
                     /gene="adhE"
                     /locus_tag="LP468_002203"
                     /gene_synonym="adhC"
     CDS             complement(3432..6029)
                     /gene="adhE"
                     /locus_tag="LP468_002203"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL2081705.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6334..6714)
                     /gene="yajC"
                     /locus_tag="LP468_002204"
     CDS             complement(6334..6714)
                     /gene="yajC"
                     /locus_tag="LP468_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL2081706.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6811..7956)
                     /gene="tgt"
                     /locus_tag="LP468_002205"
     CDS             complement(6811..7956)
                     /gene="tgt"
                     /locus_tag="LP468_002205"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL2081707.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8174..8872
                     /locus_tag="LP468_002206"
     CDS             8174..8872
                     /locus_tag="LP468_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2081708.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9040..11679)
                     /locus_tag="LP468_002207"
     CDS             complement(9040..11679)
                     /locus_tag="LP468_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2081709.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT         3425 a         2705 c         2196 g         3934 t
ORIGIN      
        1 agcgcctacg agataacctc ccataaacaa agcagagatc gaagcaccac cagcaacaag
       61 tgaatacatg ataaaagcag tacttggagg aatgaccata cctgtcggag ctgacgcgat
      121 attgaccgct gtcgcaaact tccggtcata tccttcttcc acttgctgag ggatcaacac
      181 tccaccaatc gcggtagaag cggcaatggc cgagctagag atggaaccaa ataaagcatt
      241 ccctaacaca ttcgtatgag ccaaagcccc cggcacgcgc ccgacgaaca acatcgcaaa
      301 atccactagt ttcttagcta tccctccatt attcatgata atgcccgaga gaacgaaaaa
      361 cggaatagcg atcagcgaaa aactattgat acttcccacc attttttgag ctgaactaaa
      421 agcagaaaca tcaaacggta taactaacaa taaagtcatc atcgatgaga atgcaatact
      481 tatagcaatc ggcatcccta atacaagcaa cacaacaaat acaaaaaata acactaatcc
      541 ggcttctatt gccattttat tcctccattt ttatattttt tcttgaattg ctggcttgtt
      601 gcttaatgta tcgattagat tgatcaggct atagataatg atgagtaccc ccgatacagg
      661 tactgacaga taaacatatc ccataggaat acttaaagaa ggcgagatct gccccattgt
      721 caatgtgaca gcattccatc cgccatacac catgatcatc gcagcaaata ccagaaataa
      781 actttgaaca acaacttcta aaattttact ttttttgcca gttaattttt cacttaaaac
      841 cgttacggct aaacgtgctt tttgtcccac aacatacgcg gaagacaaca tggcaaacca
      901 gacaagaccg aatcgaacaa gctcttccgt gaccgtattt ggatttccta aaaccgttct
      961 ggaaaatact tgccataaaa caacagcgac catcccaaca agcaaaacag ctcccaggat
     1021 ctctaatacc ttgtttaaaa tcattttcat tacagctacg ctccttgctc ttggatcttt
     1081 tgataaaggt ctttgtaggt aggatcgttt ttgaatatat catgaagtgg ggcaactgcc
     1141 tctcgaaacg gtgtattatc tacatcattg aattggactc catgttcttc ttgtgctaaa
     1201 gctttttctt cttcaattgc ttttgcaaaa gcttcaattt caaaaaccgt tgattctttc
     1261 gctgcttctt caatggcttt ttcctgttca tcagttagct gttctttgat ggcatcattc
     1321 atgatgatga tatctggcac acgtgtatgc tcatcatagg aatagtattt agctaccccg
     1381 ccatgtccag ctgtatacaa gacaaattca ttgttttctg atccgttgat caaattggat
     1441 tgaagagacg tgtacacttc atcacttccc ataggtacgg gcgaaccgcc taaaagctct
     1501 accattttga tagcggtttc gctttgcatc acacggatct tctttccctt caaatcttcc
     1561 ggcgtatgga tcggaccgtc taccatataa aagctgcgct gaccagaatc ataataggtc
     1621 aatccggtaa atcctaaatt tttggtcgat tggtagattg gctccattat ttcttcatta
     1681 tccatcacct taaagaaatg ttcttcatca ttgaatagat aaggaacgga aaaaatcgaa
     1741 taatctttag agaaactttc caacgctgag gcacttactt ttgtgaaatc tactgctcct
     1801 gactgtgtca attcgatcag ttcacgttct ccacccagtt gtccatctgg gaaatactgg
     1861 atctgtacgg aaccatctgt tttttctttt actaaacgcc caaattcatt cattgcatca
     1921 attactggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt acgtctgcat
     1981 ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc agacctaggc
     2041 taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc tttcttttaa
     2101 caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc ataaggcatt
     2161 gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt cccgattgaa
     2221 acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat agcacgataa
     2281 gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa aataccgtaa
     2341 gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa caacgtatgc
     2401 cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc aagtgtttcg
     2461 atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat gatctctgga
     2521 atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata gttatgattt
     2581 ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa gtatttgata
     2641 tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa cagtttcccg
     2701 atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg attcttattt
     2761 tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat gtcattcatg
     2821 acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt gtcttcatac
     2881 aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg agcgccttct
     2941 tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt ttttgtcatc
     3001 tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca cactgtccag
     3061 cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt atcgtctttg
     3121 atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc tttaggtaca
     3181 aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc attttatatc
     3241 cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa aactgtctaa
     3301 aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat taaaaaaaga
     3361 acttggagaa acaacgtttt ccaagttctt tttcatctat tttcttatct tttttctacg
     3421 ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc agagatcaat
     3481 ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc catacggtct
     3541 acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat gttgatgccg
     3601 acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc ctctgttgtt
     3661 tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc acggaaatag
     3721 tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg gataatatgc
     3781 ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc gattttatgt
     3841 gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc cattgtagaa
     3901 gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt ttctaaatag
     3961 tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga agccatgact
     4021 gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc tgtgacagat
     4081 gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt caatgcataa
     4141 tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa tggcgttact
     4201 tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc tggtttgtcg
     4261 atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa gaaagatgtg
     4321 tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga accgcctcca
     4381 agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc gtatacggta
     4441 tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc atttttacgt
     4501 cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc agggtcacaa
     4561 acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga gttcttttca
     4621 aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt cgctacagtt
     4681 ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt accataagaa
     4741 ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat gccgccttct
     4801 gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa tttgacatgc
     4861 aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag attcaacata
     4921 ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc aagaactgga
     4981 gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc agcaatcagc
     5041 attttcgttc cttttggtac actgattcct gccaattttg cgatttccat cgcagaatgt
     5101 ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc ttctaatttt
     5161 tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc ttttactgct
     5221 gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat tccattatca
     5281 aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt tttttcaata
     5341 taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga gtaagcagac
     5401 ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg gttcattagc
     5461 atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc aggagctccg
     5521 gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt ttgggcactt
     5581 ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga tttgaaaatc
     5641 gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac tggttcagca
     5701 atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt atcatgtttg
     5761 atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc ttcgtaaaca
     5821 ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc caaagctgcc
     5881 attgccattt catgcacgat atggtctact ttttcttgat caaagctttc catttctttc
     5941 aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc aattgtcttc
     6001 gttttttctt tttctattac tttagccatc attatcctcc taatgggtca tggttatttg
     6061 ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca cttttttgtg
     6121 atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt ttgtatagaa
     6181 aaatatataa agttatttat tattatttat atgacacacc cgattattca atattgagca
     6241 atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag gacatctttc
     6301 tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct cttctgtctc
     6361 ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt cttctgttgt
     6421 ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg ttttgattgc
     6481 tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc gtttgtcatt
     6541 gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat cacctggttt
     6601 catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac gtgacataaa
     6661 aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc ccattttttt
     6721 cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg ataacactag
     6781 ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt ctttattgaa
     6841 cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca tgattgcttg
     6901 acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag tcaaacgaat
     6961 cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat agtttttaca
     7021 tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt tcgcattttt
     7081 cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc gagtaggcaa
     7141 gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat cagcagcacc
     7201 gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga attctaatac
     7261 acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt aaccagggaa
     7321 atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc ctgctccttg
     7381 gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc ctcgttctgc
     7441 ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat cgaatggtgg
     7501 acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt tgattgcttt
     7561 ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca cgccttcttc
     7621 ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat ctgttaaaat
     7681 cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta agtcttcacc
     7741 agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca tttctttcaa
     7801 ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga acattggtgt
     7861 ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat gtttttcttt
     7921 cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt tctatataaa
     7981 atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag ttccctcggc
     8041 ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata acaaaaaaaa
     8101 gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta ttaaagaaaa
     8161 ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag agagtctaaa
     8221 aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg gtattgctac
     8281 tattcttctt attatgattc ctattatctt gtttgccacc accatatatg atggatcagc
     8341 gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg gcggaattat
     8401 ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc ttgatatttt
     8461 acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat tcaaaggttt
     8521 gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa cattatgggg
     8581 tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa gctattttat
     8641 ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata cgatcactgc
     8701 aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc tttcatttat
     8761 cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc tcagcccata
     8821 catttctgca acaaaagcag cattttatga acaattgcca aaagatattt aaaagagagt
     8881 gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca gtaaaagaaa
     8941 cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct cctttttgta
     9001 tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt cttctgcttc
     9061 cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag ataaaatccc
     9121 taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt gcgtaaatgg
     9181 cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta ccaaagcttt
     9241 attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga acacatgcag
     9301 aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct gacttgcgtc
     9361 tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca aggttacgat
     9421 ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa agatcccttc
     9481 atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc ttcctaaagc
     9541 aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag ctgtaaatgg
     9601 tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa tattacagct
     9661 tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt gactgacagc
     9721 gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac tttgcgccac
     9781 atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg ctggtgcatc
     9841 attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag atttgacgat
     9901 ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga cacgcgcatc
     9961 taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg acggatcatt
    10021 caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc cagtgatcat
    10081 gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt ctggacgtgg
    10141 tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg cttcagaaga
    10201 aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc tcagtgcccg
    10261 tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac taaagcgcgg
    10321 agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca tttggtgaac
    10381 tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg gatatttttc
    10441 ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg ctacttctgt
    10501 tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat ctgtacatag
    10561 tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga tattcgttac
    10621 ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca gcgttcctgt
    10681 tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca actgtcggat
    10741 gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg taacaataac
    10801 agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga acatctcaag
    10861 gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg ctaaagcgat
    10921 catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt tttgcatagt
    10981 attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa tggcagtgac
    11041 gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat taagttggtc
    11101 acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg cttcactttc
    11161 tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac gggcatcggc
    11221 agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt gctctgactc
    11281 aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca tatcttgcaa
    11341 ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg agttgatcac
    11401 aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag caaatgcggt
    11461 ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg acaagcttcg
    11521 aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca atccctgctt
    11581 ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg cttctgttac
    11641 cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc tttaaaatct
    11701 tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac ttcaaataaa
    11761 gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat ttgcaaacgc
    11821 taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat agacagaaga
    11881 atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt tcacccagac
    11941 atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg atcacgaagt
    12001 atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt ctgaaaattg
    12061 aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat ttttgtttaa
    12121 catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat catttctgtt
    12181 tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg ctttttcttt
    12241 gtcataaaat ctttgtaaag
//
LOCUS       DAFEML010000067        12134 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFEML010000067
VERSION     DAFEML010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.069"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(143..418)
                     /locus_tag="LP468_002208"
     CDS             complement(143..418)
                     /locus_tag="LP468_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL2081710.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(661..1971)
                     /gene="der"
                     /locus_tag="LP468_002209"
     CDS             complement(661..1971)
                     /gene="der"
                     /locus_tag="LP468_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL2081711.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2153..3382)
                     /gene="rpsA"
                     /locus_tag="LP468_002210"
     CDS             complement(2153..3382)
                     /gene="rpsA"
                     /locus_tag="LP468_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL2081712.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3517..4197)
                     /locus_tag="LP468_002211"
     CDS             complement(3517..4197)
                     /locus_tag="LP468_002211"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL2081713.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4246..4881)
                     /locus_tag="LP468_002212"
     CDS             complement(4246..4881)
                     /locus_tag="LP468_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2081714.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4947..6350)
                     /locus_tag="LP468_002213"
     CDS             complement(4947..6350)
                     /locus_tag="LP468_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL2081715.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6337..7368)
                     /locus_tag="LP468_002214"
     CDS             complement(6337..7368)
                     /locus_tag="LP468_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081716.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7399..7620
                     /locus_tag="LP468_002215"
     CDS             7399..7620
                     /locus_tag="LP468_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL2081717.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7785..8522)
                     /locus_tag="LP468_002216"
     CDS             complement(7785..8522)
                     /locus_tag="LP468_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL2081718.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8675..10015)
                     /locus_tag="LP468_002217"
     CDS             complement(8675..10015)
                     /locus_tag="LP468_002217"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL2081719.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10252..11775)
                     /locus_tag="LP468_002218"
     CDS             complement(10252..11775)
                     /locus_tag="LP468_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL2081720.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
BASE COUNT         3462 a         2611 c         2026 g         4035 t
ORIGIN      
        1 ataaaaatta aataaaatac atgtgttttc tatgtatgac atacggattc ggaatctctg
       61 tctcttattt attccttttc tgctaggaaa taaaaagaaa agcacttgta gccctagagc
      121 cacaagcgct ttttcaactg tcttatttaa cagcgtcttt taatgcttta cctggtttga
      181 atgcaggtac tttgctagct ggaatttcga tttcttcacc agtttgtggg ttacgacctt
      241 tgcgagctgc gcgttcgcga acttcaaagt taccaaaacc gattaattga actttttcgc
      301 cgttagctaa agcatcttga atagttgaaa atacagcatc tactgctgca gttgcatctt
      361 ttttagttaa atcagtagct gaagcaactt tttcgattaa ttctgctttg tttgccatgg
      421 atagattcac ctcctccaca agagatatga tagaaatatc atttagttaa aactttctga
      481 gtggtccaga agtttaaaaa gaaatattga ttaacttcaa tattctgtta tcacgatatc
      541 atatgaaccg cttaatagca aggtttttac caattttcac atgctttttt tagtcataga
      601 aacgtaacaa acgaaactgt ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc
      661 ctattttctc ctacgaggga taattcggat ggacgtccct tcaaaagtaa atgcttttct
      721 gatttgattt tctaagaaac gttcataaga aaaatgcatc aattcctctt cattgacaaa
      781 aacgacaaat gtaggtggtt tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt
      841 tcctttatct gttggtgttg gattgattgc tacagcatcc ataatgatat cattcaacac
      901 agccgaagag atacgaagat tctggttcat acttacttgt tcgatcattt caggcagacg
      961 ttccaaccgt tgtttagtca ctgcagaaac aaaaacgatt ggagcgtaat caagataccg
     1021 gaattcatca cgaatctctt gttcgaaatc acgcattgta ttggtttctt tctttacaag
     1081 atcccattta ttcacgacga taataattcc acgaccagct tcatgggcgt aacccgctac
     1141 tcgcttgtct tgttcccgaa tcccttcttc agcattcagt accatcaaaa cgatatcaga
     1201 acggtcaatg gcacgcattg cacgcatcac gctgtatttt tcagtatttt cgtatacttt
     1261 tccgcgttta cgcataccag ctgtatctat cattaagaat ttctgaccac tttcagaaac
     1321 gaagtgggtg tcgattgcgt ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc
     1381 ttctcctaaa atcgcattga tcaaagagga tttaccaaca tttgggcgac caatcaaact
     1441 aaacttaatc gtgtcgtcgt cctcttcttc agtctcttca gagaaatact tcactgcttc
     1501 atctaaaata tcaccaatcc ctagtccatg gcttcctgaa acaggataag gatcgcctag
     1561 ccctaaggaa taaaattcat agatatcgtt tctcatttct ggattatcta ctttattgac
     1621 tgctaaaatc actggtttat tacttctgta taaaattttc gcaaccatct catctgcgtc
     1681 tgtcacgcct tcgcgtccgc tgactacaca aatgattaca tctgcttctt caatcgcgat
     1741 ttctgcttga tgcttgatct gatccataaa aggttcatcg ccaagatcaa ttccgcctgt
     1801 gtcgatcacg ctgaattctc gacctaacca ttcacctttt gcataaatac gatcacgagt
     1861 tactccagga gtatcttcga caatcgagat acgctcacca gcgatgcggt taaaaatcgt
     1921 agacttaccg acgttcgggc ggccaacgat tgcaattgtt ggatttgcca tattatttcc
     1981 tcctcacaag tttccaatct cacttagttt aacgaatgca ttgccaactt tcaagcatag
     2041 attgtcaatt aaacgaagta tttttattcc ttattgaaat actaatcgct tttcaaaaga
     2101 aaaactgaga caaaagcagc tgctttcatc tcagtcacag atacaaaatc aattattttt
     2161 cagaatcatc ggttgctttt tcttctactt cttctttcaa cgcatcacct aaaatgtctc
     2221 ccatagtaaa tccagtattt tcttctggta attcataaga ctcaacattt tttggttctt
     2281 cttctgaagc tggtttttct tctaaagctt tgatactcaa tgcaatacga tgttcttctg
     2341 gatggatctc taatactttc actttcactt cgtcaccttc atgaagcact tcatgtggtg
     2401 tcgcaatatg tttatgtgaa atttgagaga tatggactag cccttctact ccagggaaca
     2461 cttcaacaaa ggcaccgaag cttgtcaaac gtttaactgt tccgtctaat actgtgccaa
     2521 ctggagcttt tgtatcgatt tctgaccaag gtccaggctg tgtgtctttg attgacaagg
     2581 aaacacgttc ttgttcagga ttgatagaca acactttgac atttacatca tcattgacag
     2641 ccaatacatc acttggtttt gctacatgac tatgtgaaat ctctgagaca tggactagac
     2701 cgtcaattcc gcctaggtcg acaaatgcgc caaaatcagt aagacgtgca acacgtccac
     2761 tgagaacatc tccctcatgg atagttgaaa gaatttcttt tttcttttct tctctttcgt
     2821 tttccactac cgctttatgc gataagatca aacgattttc tgatggttcg atttcgatga
     2881 ttttaaagct caatgttttg cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca
     2941 ccattgatgc agggacaaaa ccacgtacac cgacgtcaac gactaaaccg cctttgacaa
     3001 catttgtaac aggtgcttcg atgaccttgc cctcttggaa atctctttcg atatcttccc
     3061 aaactttttt agcatctaaa cggcgttttg aaagtaggta gctgccgttt tctttatctt
     3121 tgccgatcgt actgataacg actaaatcta atacatcacc gacttttact acttcgctga
     3181 tatcttctac cggcaaagtt gataattctt ttgccggaac gactccttca actccagccc
     3241 cttcgattcc gacaatcact tgtttgtctt caatgactaa aacttcgccc ttaacaacat
     3301 cgccaacttt tacttcttgt acgcttttca ttgcgtcttc cattgactgg ttgttctctt
     3361 gattttgatc aaattctgtc ataacacttg tcctcctaac caacattctg ccgtaagtac
     3421 ggtactgttt ttagtttaat tgattattca aaaaaaataa agcgatttcg ttcgttttcc
     3481 ttgaaaaaac aattgttttt catttttttt cttaatttaa aaaagaagat aacctttttt
     3541 caaaacaaca gcttttattg ctgcaacgac ttctggaatc gatttgccag tcgtatcgat
     3601 acgaacagca tcctctgctt gcttcagcgg agagacgtcc cttgttgaat cataatggtc
     3661 tctttcctgt atctctttcg tcagtgtttc aagatcagtc ggaattcctt tttcttggtt
     3721 ctctttgaaa cgtctttctg cacgctcact tacgcttgct actaaaaaga ttttcacttc
     3781 tgcattcggt aatacagctg tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc
     3841 ccctattttt cgttggacag caactaattc ttctctgact tttccatgtg cagagacttc
     3901 agaaacagct tttgtgacat ctggttgacg gatttctaaa gtcacatctt ttgatgctat
     3961 gaatacatgc tgtccatctt cttgttgcga aaaagagata ggatactttt tgatcagcga
     4021 aactagccct tcttcatctg aaaaagatac attgttcgta atagctaaat aagttactgc
     4081 gcgatacatg gcaccggtat ctgtataaat ataattcaat tcttttgcta atatcttggc
     4141 aacggtactt ttcccagatg aagcaggccc gtcgattgca atactgattt gtgtcatgat
     4201 ataactcctt tttctcagaa aaaaagccgc aaagcgcggc tattattatt taattcttaa
     4261 ttcttgacca gggtaaagca taaagttgtt tggatctaag ccattcaatt caaacaattg
     4321 atcagtggtg atccctgcac gctcagccac ttgttttgga ccttcgcctg cttgaacagt
     4381 cgttgttgaa ccggctgcag ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga
     4441 atcccctgct tgataagttg cctcacttga ggaagtcggt gttgtctctg ctgcaatact
     4501 gctttctgac gttacacctg tatcttgaga cacagtagat tcttccgcga ttgtactaga
     4561 ttctactgtt gaagtctcag ttgactcctc ttttgttgta cttgtagaac tttctactac
     4621 tgatgtcgaa gtttcagaag aagttgctgc tgttgcattg ttgcttgatc catttctgat
     4681 ccagaaataa gcacctgctg gaatagcgat acataagacc agtaaaatca aaaatagcga
     4741 aagaaataat gtatttcctt tcttttgttg tctctgagaa cttcttgatg aaacttcatc
     4801 atctgtatcg tagattggtt gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg
     4861 atgtctatct tttctgctca ctgttttacc tcctaaactc tatcgtgtgt attataccat
     4921 aggaaaaagt gtcttgtcct aaaaaatcaa tgttccatgt tttttttaaa taaatttagt
     4981 aaaatcgttt cccaatgaag ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt
     5041 tctgcttttg ctccatcaat atcacaacaa ttctgcggct tttcggagag tttttcgcca
     5101 aaataagcta agatgaattt tctgcggcag ttttcttcat taatatagcg aagcatctgc
     5161 tgcaggcgga attctttttc tttttcctga cgtttgagcc gttccaccca attttctggt
     5221 ttttcagact gctggatcag ctccatccat tttttttgca gctcatcaaa gggagcttgc
     5281 tttgtggcat attccaaata aagctcaaaa ctttgtcgct gttctctaga aagttgatta
     5341 aagaaataat ggatacgttc atccccactt tgataaaaaa gaattgctgc actttcttcc
     5401 tgatctctgc ctgctcgacc gatttcttgt acatagtttt ctagactgtc tggcaaatca
     5461 taatggacca cataacggat atcagattta tcgatcccca taccaaatgc attcgtagca
     5521 atgagaaact gcagctgatt ttttacaaac tgctgttgaa gttgtcttct ttgagctgca
     5581 tcaagaccac cgtgatagta tccaactgta aaacgttccc tgaataaatg atacaatcgt
     5641 tcgacttctt tttttgttgc acaataaatg attgccgctc cttgtgctct ttccatgaag
     5701 tgttcaagtt cttgttcttt ttgctgcgtt ttccgaacaa aaagcgagat attttgccga
     5761 ttgactgatt gtctgatctc ttttggtggt cgatcaaata gtacatgacg tatatctctt
     5821 gctactaaat ctgttgctgt cgccgttagt gccagtgtga ccgggtttcc taaaagcttt
     5881 cggatttttc ctaactgttg atattctgga cggaaatcaa ctccccattg agacacgcaa
     5941 tgagcctcat ctactacata taacgcaata ttttgttttt tcagatgctc taaaagagaa
     6001 ggattagtca acatttcggg actcaaaaac aaaaatttat attgcgatag atgacggagg
     6061 acgtatcttc tttcagattg cgaaagtaaa ctattgaaag cagctactcg tttctcccct
     6121 cgtttttgta attgcgtcac ttgatcttcc attagagaaa gcagcggtga cacgatgatg
     6181 accagacctt ccattaaata ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta
     6241 ggcaaaatag cgagagtatc ttctccatca agcaacgcct gaataatttc ttcttggccg
     6301 ggacgaaatg aatcaaatcc aaaatatttt tttaattcat ttattaacat tctgtatcgc
     6361 ttcctttctc aatagataga tttgatacaa acgaaattct ccataatcta attgtccatc
     6421 tacattccat tcgctaaagc gccactctcg cacggaatcc ttatttggtt ccaaacgttc
     6481 gattgtttct gcagagagaa tccactcgta tggaaaatca tcaaaaaaca aggcccactc
     6541 aataagatga tctgttactg ttcctctttt taaatgacgg attgccatga tctggtcaat
     6601 tgtctgacca ttcataaaca tctgcttggt gatcatcatg ctttgattga aattttgctg
     6661 taataatgaa tcgatcaaag cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa
     6721 caaaaggtgg atacatctgc tttgttgcag ataaacctct gactcatcat tgttttttgc
     6781 cagctgataa ggaagcagcc ctgttcgctc atttccagat aattggttag ctaaaaaatc
     6841 tgctgcttct tctggtatct ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat
     6901 caaaatttca cgtggcaatt ggctttcact aagccatttt tttagttgga aagtataaaa
     6961 aggacttgtc tctgctggaa gatagtcttg aatacccgtt gccagattag aaattacttg
     7021 aacagcaaat ttaatgagcc gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg
     7081 caaaccagta tgttctattt gatgttcgga caacatatca gcccctgcag gcgttagctt
     7141 tgcttcattt tcatttattt cgatccaacc ttgctgcgca attttttgca aaatttgata
     7201 aaacttatcc tgcttcaatt ctggaaaact gttatggata aacaaaagtt cgtgggtaaa
     7261 tccataaata agtactgaag tcgttcgttt tcccacaagg agttggtaaa gagaactaat
     7321 ccgcagcttg tgtcctgatg aaaatagcga taaaataaaa acaatcatat tattctcctt
     7381 aagttaggat ggttagaaat gtcactacta tgtaaacttg tacctgaacg ctgtattgca
     7441 tgcggtcttt gtcaaatcga agcgccagat attttcgatt atgatgaaga aggaatcgtt
     7501 ttatttgccc aagaaccaga ggctcatcaa cagttcgtga tgccggaaga agaaacatat
     7561 gtaaaaaaag cgtatcaaaa atgtccagtt cgagcgattt tattagaaaa taaaatataa
     7621 atataaacga aactttaaaa acgtacacta agttctctaa acttgaaaat aagccgggat
     7681 ctgtttctct tgttccgtga aatcccgact tattttgaaa gattcatttg ctatctatag
     7741 ttaattgact agttttttca cggaccctat aggacccatt tatattattt caactttttc
     7801 agccagtttt ccaatgtatt gacgatcaca gtttgctggt ctgcgttaga aatttctgcc
     7861 tctccatctc ctttttgctc accatagctg ccaaaacctc catgatttcc gccattgatt
     7921 gatacatact ctgttctttc cggtaaatac tgcttagctt cttgataagc ttcctgattc
     7981 aatactttat cttttgtcgc cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt
     8041 ccttttttgt cgggataact tgccatgaag aatacccctt ttaaatgttt gtctgaatga
     8101 ttcttattga cataacgact tgccattacg ccacctaatg aatggccacc gatcacataa
     8161 tcggaatttg gaaaatcttc tttgacctta tccgctttgt ttccgcccat cactgctaga
     8221 tcaagtggca ttttgacaat agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa
     8281 atactataac tttctggctc tacgagagca ccaggataaa aaataagtaa tggagacttt
     8341 ccatgattct ttttctctcc ttcaaaaaat aagtaatctt ctttgttttt tccttctttt
     8401 accaacactt gcgcttctga cgatggttcg tacgtatttt gctgtatata gtaataaccg
     8461 gctccaccga gtaatcctaa aatgatgact aagccaatta gtattcgtct aaatattttc
     8521 actttctccc accttttcta tctgagtgac ccctttttct taatcaagta tgattatacc
     8581 ttaaaaaaat aagagagaaa tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc
     8641 catttgaata tccgcccttt ttgtatgttt atttttattt agcacataaa cgatacacag
     8701 cttctgcata aatttccatt gctttataca tactacttaa ttcccatcgt tcattcgcct
     8761 ggtgcataaa gtcaggagta tcagggaaca tcgcaccgaa tgccacacac tggttcatcg
     8821 tacgagcaaa agtagcgccg cctgatacaa acggttcagt catgtctcca gtaatatcgc
     8881 gatatgtccc caatagattt ttcactaact cactgtctag tggcacgtat aatgaatcaa
     8941 ggaagtcaaa ttcttcataa gtcaacccat atttttctgc tgttttagtt aatttagcta
     9001 ctaaatcatc tttcttgaat gtaacaggga ttctcatatc tacaccgatt tttgtttgtt
     9061 ctggtgtgat ttccaaactt gcaaagttca tcgttagctc gccggattgt tcatcttctg
     9121 ttttgcccac gacagcttca ccagttgcat tttcttgaac taattttcct aagaaattga
     9181 ttgggccaaa atcaaatact tctgaaagag caattgccag acgagaaata gcattcactc
     9241 cttgtgctgc atctttcgcg tggatacttt taccaagaac gacgatgcct tcaccttgtt
     9301 cttcgaaatc gaattcgtgt tttttcaatg cttcttttac ttcagaaagc ttttctccag
     9361 agtaaggagc tgcatcagga acaacattca acgctcctcc agcttttaca gaaaactcgt
     9421 tcgttcctgg tcctgtcaag taagcttgca ataagccttt ttctgcataa attaaaggaa
     9481 attcagcatc tggcgcaaat ccttgcgtaa ttccttcttc tttttcgtta tatttttcta
     9541 aacaacgcca taaattttct tcatctgtac caaagataaa acgaatacgt gtcttgaatt
     9601 ccacgccagc atcaatcaaa gctttgacgg catacattgc cgcaatagaa ggacctttgt
     9661 catcttggga tccgcgacca actaaccagc cgtcttttat agttggatcg aatggttttg
     9721 tttcccaatt attttcgtcc cctgctggaa caacgtccat atgacacaag ataccgaata
     9781 attcatctcc agagccaatc tctgaataac cgtaatagcc ttctggatct ttaaatgttc
     9841 taaatcctag cttttcactg atttccaata ctttatccaa agcttcaatc acttttttac
     9901 cgaagggatg tccttgtcct gaatctgctt catctagtac ggaaggaatt cggatcaatt
     9961 cgctcaatga ttctaatgct tgttcatgat gttgttctgt cacaaatttt ttcatgatat
    10021 tatcctccta atatgttaaa aagggtcatg tcaaattcct ccgacacaac ctcttcttct
    10081 caaataatga cgttttaagc ctgctccatc agcaagcaga atgttcttaa caaatgatga
    10141 aagaaaaaac actcactgaa tggagctatt gacttgtcca cgtgcttatc gatagccgtt
    10201 tatcggtttc ttcattctta tgatagacct tgtacctgta tttgtctagg tttagaacat
    10261 tgctgctaca cctaggatca cacagatggc tacaaataat atcgcaatta atttaccggt
    10321 aaatttccac cacactgaaa catcgaaacg agcaattgct acagcaccca ttacgatagc
    10381 agatgttggt gtaattaagt ttactaaacc agatgcagat tgataagcag tgattactaa
    10441 atccttaccg acgccggcaa attcacccat aggtcccatg attcccattg ttgcagcagc
    10501 taagccggaa gttgaaggaa tcaagaatga catagggata tagaaaataa atgtaataat
    10561 gatgaataca cttgaagata atgaacttaa tccttgttcg ccccaatgta agatggtgtc
    10621 tgtgattaat ccattgttca taaccacttg gataccacga gcaacagcta ctacgattgc
    10681 tacaccgatc aaatcagaag caccagctaa aaattcagag acaaattcag actctttcat
    10741 gccataagtg attgctacta cgatggacat tactaagaat aacatagtaa tttctgggaa
    10801 gtaccagtca cctaatggaa gcatgctttt acctagaacc gtacctagta ccggaaggtt
    10861 tgttaaccag tttgtcaatg attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg
    10921 aatcaaactg atgatcatga taccaaaagt aataaagaac aatacattaa catgtttttg
    10981 ttttttcgtg attacttctt gacgaccgat tgcttcaata tcgaaatgct tcatatcttc
    11041 tttacgttgg ttgtatacta atgattttgt tggatctttt tcgatctttg atgcataacg
    11101 atacacatat acaatagaaa tagctaacaa aataacgaac atcaagaatc gaagaccaat
    11161 accttcaccc atcgaaatcc caacagcttg tgaagctacg cctgttgcaa aaggatttac
    11221 cgttgaagct agacagccta cttgagaccc tactaatacg attgctacag ctactactgt
    11281 atcaaagcct acagccatca tgactgggat cagtaaagca tagaatggaa tcgtttcttc
    11341 tgccattccg taagtagagc cgcctaatgc aaataacagc atcaatactg gaataagcat
    11401 tttttctttt cctttgaatt tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt
    11461 tttgttgata atacctaaaa atccaccaac aaccaaaatg aagaaagaga ttgggattgc
    11521 agcaggtgtt tctttagtta gctcccccgc tggtacacct agcatcccat tgattggcgc
    11581 catgaaaata tcccacagcc cttgaggatt ttgttgtact cgttcatatg atccagcgac
    11641 gatgttgcct gcatcgtcta cactatagtg cccagctggt ataaaccaag taagtacagc
    11701 gattactgca ataataataa ataagaccgt atacgctgaa ggcatttgaa attttttctt
    11761 ttttgtttgt tccatcttct tcttcctttc ttttccgtta gagacaacaa ttttggctct
    11821 aatgttattt tatcaaaaag agtatcagaa caaaaataat aacacgcatt ttgtaaaact
    11881 tttgttcaaa aagttcgttt ttccctattc cctcctcttt tttcaggttt ttaaagcttt
    11941 cttctttttc attgtagcgt ttcctttttt ttataaacaa acattttcgt cttttaaaag
    12001 gagaagaatt tcacatttgc aaagaattga ttgattttta tgcataaatc aaaaaaatac
    12061 tcaaaacaaa caaataaaac gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa
    12121 aagaccaaga aatt
//
LOCUS       DAFEML010000068        11809 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFEML010000068
VERSION     DAFEML010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.070"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            536..1099
                     /locus_tag="LP468_002219"
     CDS             536..1099
                     /locus_tag="LP468_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081721.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1160..1504)
                     /locus_tag="LP468_002220"
     CDS             complement(1160..1504)
                     /locus_tag="LP468_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081722.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(1601..1846)
                     /locus_tag="LP468_002221"
     CDS             complement(1601..1846)
                     /locus_tag="LP468_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081723.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1916..2170)
                     /locus_tag="LP468_002222"
     CDS             complement(1916..2170)
                     /locus_tag="LP468_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081724.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2334..2657)
                     /locus_tag="LP468_002223"
     CDS             complement(2334..2657)
                     /locus_tag="LP468_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081725.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2844..2917
                     /locus_tag="LP468_002224"
     tRNA            2844..2917
                     /locus_tag="LP468_002224"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2878..2880,aa:Ile,seq:cat)
     gene            complement(3302..3799)
                     /locus_tag="LP468_002225"
     CDS             complement(3302..3799)
                     /locus_tag="LP468_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2081726.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3839..4648)
                     /locus_tag="LP468_002226"
     CDS             complement(3839..4648)
                     /locus_tag="LP468_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2081727.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4982..5839
                     /locus_tag="LP468_002227"
     CDS             4982..5839
                     /locus_tag="LP468_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2081728.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5832..6734
                     /locus_tag="LP468_002228"
     CDS             5832..6734
                     /locus_tag="LP468_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2081729.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6767..7117
                     /locus_tag="LP468_002229"
     CDS             6767..7117
                     /locus_tag="LP468_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2081730.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7166..8089
                     /locus_tag="LP468_002230"
     CDS             7166..8089
                     /locus_tag="LP468_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2081731.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8167..9060
                     /locus_tag="LP468_002231"
     CDS             8167..9060
                     /locus_tag="LP468_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2081732.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9098..9661
                     /gene="amaP"
                     /locus_tag="LP468_002232"
     CDS             9098..9661
                     /gene="amaP"
                     /locus_tag="LP468_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2081733.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9675..9863
                     /locus_tag="LP468_002233"
     CDS             9675..9863
                     /locus_tag="LP468_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2081734.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9876..10778
                     /locus_tag="LP468_002234"
     CDS             9876..10778
                     /locus_tag="LP468_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2081735.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10810..11052
                     /locus_tag="LP468_002235"
     CDS             10810..11052
                     /locus_tag="LP468_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2081736.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11308..11679)
                     /locus_tag="LP468_002236"
     CDS             complement(11308..11679)
                     /locus_tag="LP468_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081737.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4188 a         1987 c         2235 g         3399 t
ORIGIN      
        1 aaaagacggt ttttttgtac gaaaaaattc attggtcgtt gaatgggctg aatagtagtg
       61 tataaaacaa ttttgtggag cgtgaagctt ttatggtaga ggaaaatacg aataaagtga
      121 tgttgataaa aagattccta tcttgaatat gaatcgagat gtcttgaaaa tgaatgagtt
      181 tgaccaatca ttatcctatc gaaatttaca gtttcgttcg attggtctgt caattaatga
      241 aaaagtaaaa aagaatatgt tctaggaaga gggcggcaca tctaaatttt taagtaacgg
      301 acagttcaaa tatcaagcat tgaaagaggc tatcctactg tttgaaggaa tacgaatata
      361 taaaaacgac aaagaggaaa aagtagttca ttaaatccct tcaagtgatg aaagaatgag
      421 atctaataaa acctgatctt tcatctgttt ttttaataac gtaataattt ttttattttt
      481 tgtgctttcg ccgttattgt agagtgattt agcattctta tttttaaaaa taactgtgtt
      541 atatattaaa aaaggcataa tagttataag cttttttaaa gaatatttag aaattattaa
      601 ttttcgtctg aaaacaaaaa aagaaagcgt tattatttta gtctattttc agggggggaa
      661 ccttatgata aaaaaactat ttttactatc aatattaacg ctagcaatgg caggttgttc
      721 tgactctggc ttagcaactg aactgatcac aaaatcaact gaagccacga cagaggagtt
      781 aaaatgtgga aacgatcaca gtgactacag aggcttaaat cgacgatgca tgggaatatt
      841 aggcagaagc aattgtaagc atcgatgtag taatcgaaga aggtgtagaa gaagcaacag
      901 aaaaatcaaa agaaagatca aaagaagcaa tctgtgctgt gcatcgtata cagacgtcga
      961 agatgcggta cttttaaacc acgtcaggag atgttcattt atgtctaggg aagttggcga
     1021 tgaaccaaaa ctagagtacg cttttagttt tgcacgtgag gatgaagata accctaaaac
     1081 ttacgacatt ttagcttgat ctaagatggt taaagctttt taatgaagta agaggagata
     1141 gaaggctttt ctagttatat taggtaagat aaattccttt ttgctccaaa tttgctaaac
     1201 attctgctag ataaacttca tcgtgttccg gataaatcgg cacgttgcgc tctacagtag
     1261 gtaaatcaaa aaatgcttcg catgatttgc cacgatacat aggatttttc cactctggtg
     1321 ctgggctgta accacgtttt tccatttcat ccatgacaag ctgatgatat tggaataatc
     1381 tataaggaga atagtgaaaa acataatcca cagtagcatg tttctttccc cagccatttc
     1441 ctcttaatgc acagcattcc cgatgttgtc ctaaaagctg ttgacgagga agctttgaaa
     1501 tcaatttttc atgccataat cacatagaaa tgtctccttt atatatagat tgttaacctt
     1561 agacgttaaa tgaaaaaacc agcaccaagg ctggaaaaaa tcacttcagt ttgcttgctg
     1621 tttctgagcg accaattagg taatcaacgg aaatatcgta aaagtcagcg atatagatta
     1681 attcaatgat gcttggaatt tcttctcctt cttcgtactt acgatatttg aataaaggaa
     1741 tacttaacgc gctagaaaca gctacttgag ataaagatcg gccagttctt aagaaattca
     1801 gacgacaacg taaagtatcc agtaaaatag cttcttcgat actcatttaa tcacctttca
     1861 ttatagtaga atagttataa tgactataga aagctacaca tgcaatcaat agtactcaat
     1921 gttttttatt taaacgtatc aaataaagaa tgacgatcaa taaagacaaa accagtcctg
     1981 ataattcttc tataaaaaca ctatcgggtt caaagtagtt gtaattaaaa actttccaca
     2041 taaagtagat agccggaaga gtcaaaatag ctaaataaaa ccgttctttg ttccaattca
     2101 taagataaac aatacttgcg accagtgcga ccgcaggcac ccaaaacaaa actctcacca
     2161 acgtaatcat gtaacggact cctcaacgat tcatataata aaagataaca tgttattgca
     2221 tacatcacaa atgaaatgct aggaaaataa aagaagaata gatcaatgaa aaatgaaaaa
     2281 gcagaacagt tttctgctga taagcaggaa ctgttccgct gaatgtgtct tatctatcga
     2341 gaaaaaatca atggattgat atctaagtaa ttcaatacat ataaaaagag gacgatcgca
     2401 ttcactaaaa aggaaagaat gatgatccca tagcgaatgg aaacatattt aacaaatact
     2461 tttgtttgaa tacgggcata tctttttcct ttatagctga gcatcatgac aagaagcaaa
     2521 agggtaatca caccttgaaa aatcattcca ataaacagaa ttcctgaggt ttgataattt
     2581 aattggagaa aataagctgc tgccgcaact aaatcgaata aaatcgcaat aaatggcaaa
     2641 ataatcactc ctaacattga gaataaataa aagaataaca ttttttctaa aataagcaaa
     2701 taaaaattaa agtaacaaaa tagttatgac acaagtaaaa gaaataagaa taacaatatt
     2761 attttactta tattttgaaa cttgtgagag tttgtcattc gtgctatagt tgaaaagtaa
     2821 caaaaataaa ttttatttat gatgtacctt tagctcagtt ggttagagca gacggctcat
     2881 aaccgtccgg tcgtaggttc gagtcctaca aggtacataa gaggttgtga aaaagctgcc
     2941 ctgcatcaag taataagaac agccaagtaa aaacagcttc ttatgttttt acttggctgt
     3001 tcttattact gcagatgcaa gcttttgaat accgtttaag gaagaggttg tgaaatcagc
     3061 gttttgacct gagtattagc ttaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
     3121 ttaagctaat accgagggtc agctgattga acaccattta agaaagaggt cgtgagcctg
     3181 ccgtttcact ctgtgtcata aaaaagccaa tctactttga tagaaaaagc acgtaggact
     3241 aaaacagttc tgcgtgcttt ttttattgtg tgttaaatat cgtaaatgaa gatagatatt
     3301 tttatgattc gacgatagag acgttgaaat ctttcaacag ctctaaagcg gattctccgt
     3361 gttttctact ggagactaac attggatcaa caaaaaagtc tgcttcagga aaagcactct
     3421 gcaggcctat cagattagag agtacacaca agtttgtttc aatcccgact acttcgatct
     3481 ctttttgttc ttctttgctt tcaaataaag tttcctggat ttcagctaaa gtttcaggtg
     3541 gaatcgtaaa gtaatacttt ttaatcactc gttcattttc ttgtggagaa agaagaggga
     3601 tcaattgcaa atcttctcgt tcttcttctt tgtccttcag ttcaactggt atatcccgtg
     3661 tgaagagaat atattcatta ttttggcgtg ctttagctaa tctttgagca atacgttctg
     3721 ccaattgatc tgactctgga atataaaatt cgctgtttgg atcaagaata tgattttgca
     3781 tatcaataat aactaacatt ttctttcctc ctacattcat atcgtcattt tattcttttt
     3841 aatagaagtt ttttaaaata taagcaacac cagcttcttc attcgtcagt gttacttggt
     3901 ttgcaatttc ttttacttgt cgctgtgcat tccccatcgc aatactcaac ccgctgtaat
     3961 tcaacatatc aatgtcgttt tcttgatcgc caaaagccat gatgtcactc gattcgattc
     4021 caaggtaatc cgccagaaaa acaagtgaat gagctttagt gatacctgta ggcgtgattt
     4081 ctaagaaatg cggatcagag aatactgatt ggataccatc tgcttgcaga tctctttgta
     4141 gcttctgtag tttttcttca ctcttatctg ttaatgctaa tttaagatag ctaagagaag
     4201 gatcttccaa catatttaaa atttgatcaa aagaatggtt ctgtaaattg aaatgttcat
     4261 aataagggtc atctttgact agatttgatt catcgaatgt cagctgatca tcttgggttt
     4321 ctcggctagc aatgatggat attttcgctt cttgagcata gaagaaggct tttctcagtg
     4381 tatcgctatc tatttttgaa cgtctgagaa ctttcgccat ttttccatcc ttcatttcag
     4441 caatcagtga accattggaa gaaatcaaat agccaccgat tcctaattcg gaaaaaatat
     4501 ctttagcaga aatgctgttc cttccggtag cgacggttac gattccgcca ttttcatcaa
     4561 atttccgaag tgcttggata ttttcttctg gtatctttcc atttcgatca agcaaggtac
     4621 cgtctaaatc aatcgctgct agtttcattt tatcttccta ctttcttttt acatatctat
     4681 tttcctgtta ccttaagatt aaatgagaat ttaaaaaaat gaaactaact tgctttgtca
     4741 ttatgaattt tttcaaaaaa cattcttaag aaaaaggtgg ctatatatag tagtttttgg
     4801 tcaatacctt tgaataaaaa gccatgaaaa acgaatagtt agcgcttacc gatgcgtttt
     4861 gtgataaaaa aattttaaaa tattcaatga aaacaaagca tatattttgc tttaaaacca
     4921 aatgaggaat attctagatg tagaacaggt tagaaaaaga ttagaaaaag gagtgatttt
     4981 gatggagaag agatacggcg tagttcctgt ggtaactgct tcagacgaaa attatgctcc
     5041 ttacttgagc gtgatgatcg caactgcatt agaaaattgc aataaaacaa gacgcataaa
     5101 attttatgtg attgacgatg gtctatcaga atatagtaaa gaaggattgg aagaaacggt
     5161 aaataaatat tcaagtaatg caagtatcca attcctgaca gtggaaaaag atatctacga
     5221 agacttccta gtcagtgacc atatcacaac taccgcttac ttaagaattt ctttaccaaa
     5281 cttattagct aaagaggatt ataagaaagt cctttactta gattcagatg tgttagtact
     5341 agacgatatc gtaaaactat atgatgagcc gttaaatgga aaaacaatcg gcgctattat
     5401 cgatccaggc caagtgaaag ctttggaaag attaggaatc gattccgatg acttgtactt
     5461 caattcagga gtgatggtga ttgacattga tcaatggaat aaaaaagaaa ttacagaaaa
     5521 aactatccat tacctcagtg aaaatggcga tcgaatcatc tatcacgacc aagatgcttt
     5581 gaatgctgta ctttatgaag attgggaaca acttcatcca aaatggaaca tgcagacttc
     5641 gctgattttt gaacgtcatc cagcaccaaa tgaaaaatat gaacgtcagt ataaagaagg
     5701 aaatgaaaaa ccttcgatcg ttcactttac aggacatgat aaaccttgga atacgttgaa
     5761 agatcatccg tataccaatt tatacttaaa aaaattagca cacagtactc taacgaaagt
     5821 aggcgagatc aatgaataaa aaagaaatag cagtagtcgc aagttgtaac acaaaattcg
     5881 taccacattt agctgcatta tttgtctcag tattagataa ttgcaacccg tctaaatttg
     5941 ttcggttcta tgtgattgac gatgatatcg attttgaaag taaacagctt ttacgcttct
     6001 cagtgaaaaa cgcacgaatg aactcagatg tggaattctt gaaaatcaat aaagaattct
     6061 ttacaaatgt ggtaatcagc gatcgtattc cagaaacagc ttattatcgt attgcgattc
     6121 cggaattgtt ccgcggcaca gaagttgaac gtatcttata tatggattgc gacatgatcg
     6181 ctttacaaga tatctctaaa ttatggcgtc ttgacttcgg tgattcaatc gtagcagctg
     6241 ttgaagacgc tgggttccat caacgactgg aaaaaatgaa aatttcagct aaatcaatgc
     6301 gttatttcaa ctcaggtttg atgctgatca atgtgaaaaa atggttagat gaaaatatta
     6361 cgcaaaaagt attagatttc atcgaacata atccagaaaa attacgattc catgaccaag
     6421 atgcattaaa tgctatctta catgaccgtt ggttaccact tcatccgcgt tggaatgcac
     6481 aaggctatat catggcaaaa gcaaaaaaac atccaacagc agcaggtgaa cgtgaatacg
     6541 aagaaactcg caacaatcct tacattatcc atttttcagg acatgtgaaa ccgtggagca
     6601 aggattttga agggccaacg aagaaatatt acgaaaaata tgcagggatg acggctttcc
     6661 gttgtgtagc taaattccct aaatatccaa aatatgcaaa agttcaacca aaaacagatg
     6721 tagttgttaa ataatagaag acaacaactg aagaggggga gtaggaatgg aaattacaat
     6781 gtctaaaaat gcagtagaga cgttaattga aaaggttggg gaaaatacaa aaatcgcact
     6841 cgcgcttatc aatgattccg atccatttct aagggacaaa ggtgcttttg caaaaggcag
     6901 cttttttcaa atcattcctt ttgtttcgga atttggagaa tatgcgacta aaatcgagca
     6961 tccattattg gacatctata catctaaatt agagcaaaat tatttcggta aacgattgaa
     7021 catggacttc aacaaacagc ttgacagctt ttcattagaa aatgaaatcg cagtactcga
     7081 ttataatatc aaattaaaga actgcttctt cagctaatag tttcgagaaa gtccaaaaag
     7141 gaggtataca ttgagatact actttgtgga tgaagaaaag aatgtaatag aaacagatga
     7201 aaaaaaatat aattggctcg tacttgatag tgcaaagccc gaagagattg agcaagcaat
     7261 cgaagaattc gagcttcctg atgatatttt cgtaggaacc gaatatccgg aagaagtttc
     7321 tcggatggag cgcctttatg agacgaaact agagcatcca ttttctttgg tagtgattaa
     7381 tctagatcag tcagataatc gtatcgaaaa aaaattaacg ccaatatctt ttgtactttc
     7441 cgataatctc ttgattactt gtatcgatag aaaaaccgaa tttgtggatc ggctgctgac
     7501 aaagcatgga aatcatttaa actcgtttga aaagatcatc acgtatacat tattagatat
     7561 ttacacccat tacgtgaaag aactaagaga gatgaaaaag cgaattgacg ctttggataa
     7621 agcagctcgt aaaacaacgg aaaatgaaga actgtataaa caggcagatc ttgaaagaga
     7681 catcgtatat atcgatcata ccttaagaga tcaacgggaa acaatggatc aattatggaa
     7741 ttctgaaact ttcatcaaac gtttagacga tgaacagcta ctctatgatg tccatttgag
     7801 acagcgacaa acagaaaaaa tgatcgagat ctatcgagat ttattagaga gtattggtga
     7861 tctattcaac gggatgatgg acaataatct aaatcatatc atgaaatatc tagattcagc
     7921 tgcattaatc atttccgttc cggcgttgtt cgcagggatt tggggaatga atacaggagg
     7981 attaccgggt aaaagttctg ctctaggctt tatactcgta gtctttggct ctttgatagc
     8041 agcagtagtt ttaggttacc atttataccg gaaagattat acaaattaaa gaatctattt
     8101 aaaacaggta tcaaacaaag aaatttgttt tggcaataca atttaaaaac taggaggaat
     8161 acagcaatga cagaaccaaa attaatcgac ccgcgaaact tgtaccatac ggagaaattt
     8221 cctaaacaag atcaggatac accagcttta cagcagaata tgattcctgt tcctgattgt
     8281 ggagaagaat cctatgaagg caataatcaa ctagaaaacc gccgtgtact aatcactggt
     8341 ggagattcag ggatcggtcg tgcagcagcg attgcatttg ctagagaagg ggcagatatc
     8401 gctcttcaat tcttcccagg agaagaaaaa gatgcagagg aagtagcaaa atacgtgaaa
     8461 gttgcaggac gtaagattgt cttactacct tttgatcttc gtgacgaaca agcacctaaa
     8521 gaaatcatag ataaagccgt gagtgaactt ggcgggctag atacgatggt actaaacgca
     8581 ggacagcaaa tttcttgtca gtctattgct gagttaccac ttgagcaagt caaagacaca
     8641 tttatgataa acatcatcgc tatgtttgct ttagtgaaag aagctgttcc gcatatccca
     8701 gcaggaggag caatcgtaac aacaacttct gttcaagcat tcaatccaag cgaacattta
     8761 ttagattacg cagcaacaaa agcttcaatc gctaacttta cgatcggttt agcaaaacag
     8821 cttgcaccta aaggaatccg tgtaaatggt gtagcacctg gtccaatctg gacaccatta
     8881 caactagacg aaggacaacc ttctgattcg atccctgaat ttggtcagca aagtttacta
     8941 gaacgtgcag gtcagccagg agaattagca ccagtttatg ttttcttagc atcgaataaa
     9001 gcaagttatg ttacagccca aatttacgga gtaactggtg gagaagcgat caacttataa
     9061 gaagttgatc gtttcacccc tatgaggagg tgcgaaaatg aataaaggtg taaaaacgat
     9121 cggagtgatc ggaacattac ttttgctatc tgtgcttttg tttgcgatac tattaagtgc
     9181 aacctatcca ttgccttttc agctagagaa gtttcgattc ttttccatca ctaattcata
     9241 cgtgcaacaa tatgtatttt ggcttgccgt tgcatttgct attttgacaa ttatcacgtt
     9301 acttgttttc ctgttttatc caaaaacaat cggaaacttt ctactgaaac atggtgatgg
     9361 ggagttgacg ttggataaaa aagcaattga aggaatggtt cgttctcact tgcatgaaga
     9421 tgaattcatc cattcaccaa aagtaaatgt caaagcaacg aaaaacaaga tcgccgtcaa
     9481 tgtaaaaggg gagttgaaac gaacttcagc actcattggt aaaacaggaa cattgatgaa
     9541 agaaatcgaa aatgaagtac aacacatatt gggaacaaaa gagccagtga aagtatcggt
     9601 gaaatacaca ggctttgaag aaccagctaa acgaagcaat gaccgcaaac gagtagaata
     9661 gggggggacc aaaaatgaaa gaactatttt cgacatacaa gctccctatc atctttgggg
     9721 tacttggatt gatattagcc gttttatgga tcaccgtggg ctttttcaag accttattga
     9781 tcttgatcat ggcagcgatc ggcgtcgcta tcggttttta tctgaaacaa acgaaaatct
     9841 tagatcacta ttttaaatct taggaggaaa catccatgaa taacaataac aaaaataata
     9901 acaataaaat gaacaaccaa aaaccagtgt ctgcacatcc agacccaacg acaccaaacc
     9961 aatcaaatgg tgtgaacgat gaaaagaaca aaacagcacc agtatctgca catccagatc
    10021 cagtagtccc taacgttcaa caaggagtag aagagaagaa acatgatgca gaaaagcatg
    10081 cacctcatca tccaggaact ccagaatcta aagttccaga acaacatgat gcaatcgatc
    10141 cttctaaacc tgtggaagag caaaaacatc cttctgacca tgcgaaagca caagaaaaac
    10201 ttagttctga ccacacaaac ggacaaggaa aacttggttc tgatcataca aataaccaag
    10261 gaaagcatga ttctgaacag gaagattcaa tgcgcggtga gctgaattat gaagataaag
    10321 ttgtgcaaaa aatcatcgga atcgcaattg aacaagtaga cggtttatta tctgcaaacg
    10381 gtggtttctt ctctaatgtg gcaggaaaac ttgtgaatac agataatgta acggctggga
    10441 tcgaaacaga agtcggtaaa aaacaagtag cagttgatat ggatgtcatt gtggaatatg
    10501 gcaaagatat cgaaaaaatc tttgaagaaa tgcaagaagt aatcggcaaa gaagtaaaaa
    10561 atatgacaca tttagaagtg atcgaagtca acgctaacgt agtggacatc aaaacaaaag
    10621 aagaatttga aaaagatcaa gaaacggtgc aagacaaagt aactgacgca gcgaaaaaaa
    10681 ccggtgaatt tgcttcgaat caaacagata aagtaaaatc agcagctgga agcggcgcac
    10741 aaaaagtaaa agaaaataca gaaccacggg ttcagtaata aggaagtaaa acattaggag
    10801 gaacgaaaca tgggatttat ttggtcactt atcgtcggag gaattatcgg agcaattgca
    10861 ggagcaatca cgaataaagg ttcttcgatg gggattattg caaatgtcgt agcaggttta
    10921 gttggatcag cacttggtca agcattatta ggttcttggg gaccaagtat tgcaggaatg
    10981 gcaatcgtgc catcattgat tggtgccatc attttagtac taatcgtatc attctttgct
    11041 cgaaaactgt aaaaagactt ttaaaaagag gtcgtgaaaa agctgttctt catcaagtaa
    11101 taagaacagc caaacaaaaa tagcttctca tatttttcat ttggttgggc atattatcga
    11161 agatgcaagc ttttgaacac tgtttatacg gaataagagg ctgtgacaag acttttgtca
    11221 cagcctctta tttatgcggg caaattccca attagatttt taaaagtttt tccttaaatg
    11281 tgtctttatt gatacagaga agcttcttta ataaaacaat gcctccctaa attttcttga
    11341 gataggaaag gtgaacatac aaaataatac gaccactttg aaaacccaga tgatccacaa
    11401 atggatcgta tgatactgat gaagtaaaaa gcaatggatc agaaactcaa agagattgaa
    11461 aaagacaagg aagaaataat atctcttttt tactcttgtc tgttttagcc aataatagct
    11521 cgtaaagtaa tctagacaaa caaatagaag taaacaaagt ttcgtaagag cagcaatcgt
    11581 atcatgttgc tctgctagac gattgacgag caggaaaaat gttggtaatg gaatatagat
    11641 cacgagtaat gaaagaaaaa agtaaacaat aaatggcata ctattcctcc taattgtgtg
    11701 agttcgccct cattttaaaa taacgatatt tgtttgtgaa gctttttcgt gtcgtaacaa
    11761 atgttatcta atgtattttt aaataaataa tcattattat caaaataat
//
LOCUS       DAFEML010000069        11254 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFEML010000069
VERSION     DAFEML010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.071"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(57..980)
                     /locus_tag="LP468_002237"
     CDS             complement(57..980)
                     /locus_tag="LP468_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081738.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            complement(1503..2507)
                     /locus_tag="LP468_002238"
     CDS             complement(1503..2507)
                     /locus_tag="LP468_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL2081739.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
     gene            complement(2578..2874)
                     /locus_tag="LP468_002239"
     CDS             complement(2578..2874)
                     /locus_tag="LP468_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081740.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(2867..3160)
                     /locus_tag="LP468_002240"
     CDS             complement(2867..3160)
                     /locus_tag="LP468_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081741.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(3306..3857)
                     /locus_tag="LP468_002241"
     CDS             complement(3306..3857)
                     /locus_tag="LP468_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBL2081742.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(4031..4330)
                     /locus_tag="LP468_002242"
     CDS             complement(4031..4330)
                     /locus_tag="LP468_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBL2081743.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(4357..4665)
                     /locus_tag="LP468_002243"
     CDS             complement(4357..4665)
                     /locus_tag="LP468_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL2081744.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(4782..5741)
                     /locus_tag="LP468_002244"
     CDS             complement(4782..5741)
                     /locus_tag="LP468_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2081745.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            5885..6661
                     /locus_tag="LP468_002245"
     CDS             5885..6661
                     /locus_tag="LP468_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081746.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            complement(6759..7406)
                     /locus_tag="LP468_002246"
     CDS             complement(6759..7406)
                     /locus_tag="LP468_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2081747.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(7406..8236)
                     /locus_tag="LP468_002247"
     CDS             complement(7406..8236)
                     /locus_tag="LP468_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081748.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            complement(8236..8985)
                     /locus_tag="LP468_002248"
     CDS             complement(8236..8985)
                     /locus_tag="LP468_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081749.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            complement(8999..9463)
                     /locus_tag="LP468_002249"
     CDS             complement(8999..9463)
                     /locus_tag="LP468_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081750.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            complement(9513..9974)
                     /locus_tag="LP468_002250"
     CDS             complement(9513..9974)
                     /locus_tag="LP468_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2081751.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            complement(9956..10945)
                     /locus_tag="LP468_002251"
     CDS             complement(9956..10945)
                     /locus_tag="LP468_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2081752.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
BASE COUNT         3576 a         2077 c         1551 g         4050 t
ORIGIN      
        1 ttgtgatttt ggaaatcaca acttttttct tttacgataa atcaatcctt attaaattat
       61 ttaggaaaat attgttcaat tatttcttta tatattttct catagtatgt ttctgtccat
      121 cctaatgttc ctataaaatc aagtcctcta cattttaaag gttcacttaa actattaata
      181 tagttaataa tgttgtctat ccttttctct ttatcttcac cttcaatctg gggagcatat
      241 agtccaattt cctcccaata atatgaatct ctttcaattc ccatgatggt agctttggct
      301 aatttcaaat caaataacga ttttagaatt cttagtgtct caataaagtc ttctctcttc
      361 aactctttaa tccattgtga attttctgga ttatctaaaa tttcaagttc atcttcatta
      421 taagtatatt tcaaatttga cttgcttaac tcatagataa atgaagtttc ttgactcata
      481 attcttttaa gtacttgact ataagtttcg tttgactttg cccatttcgc taattctacc
      541 actgtattca ctaataaatc gaaataatga tgttctcgtt caatagtctc agcattttga
      601 aaatgaaaat cacctttata aactccattc ttttccactg ttttattaat attttttaaa
      661 aaccagaatg agtttgcaaa tttagtcgta ctttttcgat taactaagtt aataactctt
      721 ccatgtaata ataagacaaa aatacataaa tttttagctt ccttattatt agatactaat
      781 tgatcaatca tagggagcca ttttttgatt ttcactaatt gattgctcat aaatctttca
      841 ctggactttt gttcaatctt aaattgcaaa acttctaact cataattccc atcttctgat
      901 ttatttttgg gaacaactat caaactttta taaagtttat ccacatcaaa atttatcttt
      961 tttgcataat ttgtagccat taatacatct ccttattcat aataaatttc atatgacgct
     1021 cctctcaaaa tttaccggta gactagaaaa aagaataaaa gatacgtcaa ttcacacttt
     1081 attcttaaaa aaaaactggt ctctctaccg gtaatatcga ttgagtccgc ctttatcgac
     1141 tttatccttt ttttatatta aattttttca ccggtagaca gggagagaaa gaataaacta
     1201 aaaagccctt aattcttaat gttttcacct ccttaccgtt cctaccgcta aaatttaata
     1261 taactaaatt ctataacatt agaagaaatt ttaaatacct ttgataaaaa atattgatgt
     1321 tttttctctc attgtttaca aactagatag cttatgtatt cttattaaaa ataatagata
     1381 tttcgaacat catcactctc atctacttaa tttcgcattt ttactttata aaaaaactga
     1441 ttctaagaaa attaaataat ttttctcaaa atcagttttt ctttgataaa taatattttc
     1501 aattatttaa tcatttgaaa attgttagtc attccaatac gttgagaaat tcttccatct
     1561 gtataaacac ggaattgttt tccaccagcc attgttgtat ttccattatc atccgttaca
     1621 atattaattg aatagtagct tccattttca tcttgcatta gatctttcat atattcattt
     1681 gtgctaatta aattagtatt tgatgcattt ttatcaggag aatcatacaa ccataaagct
     1741 ttattattta gtacagtttc tttagcagct tcccaacttg aaattgctga gctacttgta
     1801 gattgtgtcg ttgtagttgt tgcttgttga gtagattctt ctactactgg agtttgagga
     1861 gtttgtccat tcacaatatc aatgaaacct tgttttaact gttggttctg agtttcattg
     1921 aagtacatgt agtttttatc attgccttga ttttgttgcg ttaaataaac tttaggttgt
     1981 ccattttgaa agccaaagaa atatacatgc tgccctaaat attctccagt ttctacatca
     2041 gaataaactg ctactaaatt gaaatctgca tgaccagttc catcttctga ccattgtacg
     2101 gtaactggtg cttcattgat tgccattttc caatttccat caataactgc acttggtaaa
     2161 ggcgtaccat acagacttac attgttctga ggattgtagc ttttatattc ttgacctaat
     2221 gtctttcccc attgtgggac aaaaattgct agttgagtag atttctcact atcccacaaa
     2281 gtatttttaa cctcttcaga agaagattca atgattgaac tttcacttgt acttgcttcc
     2341 acagattgtt tcatttctgt tgtagtttgt tcagttgatt gcgttttact ttttttagcc
     2401 tcaattgttg tatcagtttc tacagtctct ttagtcctcg tattctcaga tgtacaacca
     2461 gtgaataaaa tccccattcc aattagtaat aacaaccatt ttttcatttt atttccccct
     2521 ttcaatttct ccctcgcgta cttattttat cagtcaatta atctcaatgg tgttcattta
     2581 gttaatcctt tcccaagaat gtcgatagcc agcatgacaa cgatctcttc cttgagggct
     2641 ttcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc gataagttct
     2701 cattattttt gggctattag tattattttt cttagttaga gctatgagtc caactatgat
     2761 taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa gcatatattt
     2821 atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag ccatgtactc
     2881 gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa ccataaactt
     2941 ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg attctttttc
     3001 taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct cgaaaagcaa
     3061 gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag tcattcatac
     3121 ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc cctgttattt
     3181 tttacataat gaaaatagca tattactggg tacattgata attcatataa catgtatcat
     3241 cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca taagaaaata
     3301 aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc attacgaaca
     3361 tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt ggtcatcttt
     3421 ttttgtttcg cactcaattg atcgtaaatg gtcttcgctt gttcataagc cacttgactc
     3481 gtcgctgtaa tcgaaccaca agcaaaaata atggtgttga ttttcttttc tgtgaaaaca
     3541 gttgttaata tttccaaaga ttgttcatca tttccacgag gaaatacccg aggacttttc
     3601 gcttttgtat acgaaaaaag attcacagca ataaaaccag taaatcctaa ttgtcggata
     3661 ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc tgttggacga
     3721 atagtaatga ctaccgctaa tttatcttcc gcttcttttc ctttgatcgc ccattgtcgt
     3781 ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg tgtggtcact
     3841 aattcttttt caatcatctc tttttctcct atgctaattt ttgttcaagc aattcaatca
     3901 ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt ctcctttttt
     3961 cttcagaatt tgatgaatcg ctgtaaggat atcttctaaa catttcgcaa tcattctcaa
     4021 ataatcgatc ttattcattc gttcctccaa tctgactcca aaccaatcgt ccttctacca
     4081 gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa actacatagt
     4141 cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa cgtggtagag
     4201 taacatcttc aggaagcata cccatttcaa tttcctcttt ttccatcgta acggattcat
     4261 agccccactc ttcaggagta gtgactagct gtgcacactt ttccagtact tcgatagccg
     4321 tttctaacaa gtcctttcgt tcctttcttt tagatatcag tattcttctg gtaataacat
     4381 cgtttgatac tcacccgaat caatgaccca tattttttga gacactgatt tcaaacgaag
     4441 cttaggtgaa atcagatact cttttcttgc ttctggttct tcttgacgat gaaccaactt
     4501 ttgatttcct ttttccgtag aaaattcaaa gatttgaaga tagtctaaat gaaattgctt
     4561 ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg gcaaactgtc
     4621 cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt ttccctcctt
     4681 tgccataaaa atagcccaat cttctattaa agaagattgg gcttcatgga tataatatat
     4741 atttgatatt caatttgatt cattttatac tatctgattt gtcaaattaa gctagacaat
     4801 atgtctttat ctatgcagct caaaaatact tccaatggtg ttcgataatt taatgatttt
     4861 cttggaatat ggtttctttt cgaggcaacg gattgaataa aggtttcatc cgtgtcccta
     4921 aagtccattg ttttaggtaa gccatctcgt ctaagcaagc cgtttgagtg ctcatttagc
     4981 cctctttgcg aaggtgttcc tggatctgcg aaaaagatgg caatatcgtt cgagttactt
     5041 atagatcgcc agttggaaaa ttcttttcca caatcaaatg tcatggattt aaacaagtgt
     5101 ttaggcatgg atttgaacca atcatttaac ctgttttcga tatcttcggc tcgtctgcct
     5161 gtcggtttca aagtaataat aaccttggat aaacactcaa ccaatgtaat aacagcgctc
     5221 ttgtgtttaa ctcccacaat ggtgtcgact tcgagatgac caaattcttt agtcaggtgt
     5281 ggatagagac tgttccgttc atgaatcgtt ctgcgaaagg cctgttttcc acgcttttct
     5341 tgatgattat tcggtttacg tttccccttc ataggtaacg actgtgtgtc aaaaaggcct
     5401 tttttaaaca tccgatagag tgtacgaaca gaacaatcaa ttggaaactc gccacggccg
     5461 ataatcacat cgggtgacca tccttgagct accttttctt gaacatatgt tgattgttca
     5521 tcagataaaa cggttgaacg tcgtccacaa cgagatttat tttgtttgta ttgacggtaa
     5581 taatctagca ctttttttcc ttgtttgaga aacgaataaa cattataaat ggtttgtcta
     5641 gagcgattta aactttgtgc gacaagagcg acaggtttct cgatattgaa ataagactct
     5701 atgattacta gttcgtctgt tgtaagatgg gtgtaagtca tttgtactca ctccttatta
     5761 attctttggt cggaactatt ttgagtgtag cacaaatgat ctttttagtt gtctagctta
     5821 attttacaat cgacgtttta ataaattgtg atataatgaa gtataacttt ttagggagtg
     5881 tactatgaat tttcaagata atagaccatt atatttacaa gtagaagctt ctatacgtaa
     5941 cgatattcgt gaaaaaaaat atcttccagg agagcaatta cctacagaag aagaattatg
     6001 taaaatttat ggagtaagta agattaccat tcgaaaagct tttaaacttt tagcagaaag
     6061 tggaacagtt gaacgattaa gggggaaagg gacctttgta actcaaaaaa aagaaagttt
     6121 aaaattagct ggagttcatg gatttagcga ttctctttct acccgaggac ataaaattag
     6181 atatactgtt ttacattcta aaattataaa ggctgatgag tttttagcta ataaattaca
     6241 aatcaatgta actgatagag tttacaatat taaacgttta atgtgggaag acggtgcccc
     6301 gatgggaatt gataattttt tcgcatcaga agaaaaattt ccaactttat ttgaaaaagg
     6361 tagccaatat acttcattat ataaacttct agaagatgac tatgatgtca aagctacgag
     6421 ctctattatg gaaataaacg gtttatctgc aacacctgag ctttccgact tattgcaatg
     6481 tatagtagga gatccgctat ttattttaga aaaggttggc aaagataaaa ataatcaacc
     6541 atttcattat tctcaatcca cagttcgttg tgatagaatt agttatgtta ttgaagtcac
     6601 agaaaatatc actttagata cggtgcataa aaatgattca gatcctaaag taatagattg
     6661 atattaaaag aaatcatacc caaagcaatc aattttgatt agatttgggc atgattttta
     6721 tttttactaa tattctctaa atacatcaaa aaacttattt atattccaaa tttcacctgt
     6781 acttcttgtc gcagatattt aatatcgtaa ataacatcat ctgctagact tacatcttga
     6841 gaaaaacgtt tatctttaat tgcaagaacc ttcatatttg ctcttttacc agcttttata
     6901 ccattataag aatcttctat caccagacat tcttcaactg gaattctgag ctgttctgaa
     6961 gctttaagga atatagtagg attaggttta ctttctggca aatctcttcc gctaattaaa
     7021 caatcaaaat atgactctat tttacaagtg gtaacaactt catttatagt atccattgga
     7081 ctggaagaag caattgccat ttttattttt ttctttttta accattcaag ctgttcaatt
     7141 agtatattag gaaaaatatc caagtaatca atcttttgcg atttccaata tttagtaaat
     7201 tttcccttca attctaaact gttacatccc tcattgtact tttctatatc atcaaaaata
     7261 cttgctgtag ttccaatctt tttttgataa gaatacaaag gatagcttaa attttcttgt
     7321 tttaaaaaat taaataccca cttttgatac ataatctcgc tatcaattaa aactccgtcc
     7381 atatcaaaaa ttagagcctt aatcattata agatacctat tatacttaaa acaaaccctg
     7441 ccaaaataca acctaataag agcatatttg tactaacatt tttcttaatc aatttatata
     7501 ttcccaaagt acatacaagt ggtaataatc caggaataat ggaatcaagt aagtcttgta
     7561 aaacaagttc tgttccccct gtagtgaatt ttaaaggggt gacaattggc accatgctag
     7621 ccaccattcc acctactaca gccaaaccaa tgatagaagc aaattgcatt actcgatcca
     7681 taagaccttc ttgatacaat ttagtaaggt atttattgcc agactcatat cctaatttac
     7741 cgccgtaaaa aacagctaaa atagaaggta tagcaaaaag gccaacagct aaaatcggtc
     7801 ctaaaatact accttgctta gcaaaagaca atccaatccc aaatgtaata attcttaaag
     7861 taccttggaa aaatgaatca ccaattccag caaaaggacc cattaaactg gttttaatca
     7921 tggagataga ttcagtatta aagtttcctt cttctgcttg agcattttgt tcttccatag
     7981 aagcacaaag tcccataata aatgaagtca tttgaggcgt acagttaaaa aatgccatat
     8041 gacgagtata agcttctctt tttttctctt catcattttt ataaacttta tttaaaattg
     8101 gcgccatccc atacataaat cccatatgca tttgtctttc ataattccac gaacacatga
     8161 ttgtccatga acgaagacac atcttattaa gatctttttt tgtgattaaa cgtttttttt
     8221 ctgtactatt ttccattaac catgcgcctc ttctcttttt ccatatttaa cttgatccat
     8281 tacaaaggca atcagagctg caaaaattgt cacgccaatt agtgaaagac ctgaataggc
     8341 aacaataaag aatccaaaaa taaagtaagg atataatttt ttactcaaca ttgtgcttaa
     8401 tagcattgca aaccctaatg cggaaagcat atttccagag acagtcaagg cgtctgtaat
     8461 catttctgga attttatcta ctaaatctgc cacaacgtca gcaccaaaat atactgttaa
     8521 aaagattgga ataaagtaaa caaaagcatt aaaaataaat gaccaataaa tatgaataat
     8581 ttgagctttt ctaaatttat tattttcaat ggctttatct gcagcatgtc caaattgagc
     8641 aattatcatg cgcatgataa tactcataaa ttcaccagct acagccactg ggatagctat
     8701 tgttaaggct gtttctgtac tactattagt taaaattgca aaagcagtgg caataatact
     8761 accaagttgc atattaggag gtccagccgc cccaattgag acgaatccca tagaaattaa
     8821 ttctaaagat gccccaagaa caatccctgt atgcaagtca cctagcacaa gtccggcaag
     8881 tgtactcaaa attagtggtc taccaatatt ttgtcgacca attaacctgg agtcaataac
     8941 agctaccaca ccaactaaac ctaataaaat ggcttttaat aacatttatt ttcccccctt
     9001 acttactaaa atctacattt tcaatacttg aagatgggac ttgttgcaca aatattttca
     9061 cttcttgatc aagaattttt tttgtggctt ctaattcttc aggagttaaa aagactgcct
     9121 ttccatattg tttggactcg cttttcttag acacaccgcc aaaattaatt tctttaattt
     9181 ctggtaaatt ttgaactaat tcaaaagctt ccttaggtcc tttaattaaa atcatgtaat
     9241 tatcatttgg ggatgtttcc ataatccctt taacatcact aattttaaca atgtctaatt
     9301 tgcaatcagc aggtttagca attgtcaaag ccatcacaga cattggatct cctggaactt
     9361 tgttatcagc cacaataata tggttaatat catactgttt agtccaagaa aatattactt
     9421 gtccatgaag taatctgtgg tctacacgca ctaatttaat cattctattt cctccttcaa
     9481 tttttaaaat ttatagaata gaaattgcca ccttaactga catcttttaa aagcgaatta
     9541 atatgaacca tacttttttg agagttattc agtaattcct taaaatctat ttcttctata
     9601 gatttaccag ctgactgggc cattaataac tccagtaaaa gaggtaaatt aatcccagca
     9661 ataatttgaa ttctattgtt gttcaactgt ttaatagaaa cattattagg tgttcctcca
     9721 attaaatccg ttaaaataat tagaggttgc aaatgatgct gactaattat ttctttcata
     9781 ctctcctcaa aatcatctgg actagtattt tctttaaatg gaacagcact aatacctgtg
     9841 gcgtcattca ttaaaattaa ttttgttgcc tttaaataac cctcacaaag ggtagaatgt
     9901 gttgtaatca caatgtgaaa taattgattt gccatctttt gcaacctcct attaattaat
     9961 atttcatttg ccacatatag cgtctaacat ctaaggaatg gcctctttca aaagcaatcg
    10021 cttctaccat ttggcgaata acaacgccac taagtacagc tgcaatatat tctttcgcta
    10081 cactatctat agattctaag tcaaaatcag cttggtctaa aaccattaat ttattactga
    10141 attttttagt gaagtcttct acccgttgat ctaaaaatct tgtatctcca atacttttca
    10201 ctaagatgaa tggtacatca taatcagtga tttcaaaagg accatggaaa aattccccag
    10261 aatgaatagc attagaatta atccattgca tttccatgaa ccagcaagct gctgtggagt
    10321 aaatttctcc gtaattgata ccgctaccaa ttgtgtaaat aattttatct cgtttttggt
    10381 ttttacccca ttctttagca gttatttcaa atttgctctt ttcagcaata acaagatcat
    10441 ttaacttatc aaattcattc aagcaagttt cccatttttt agagccatct aaaacaagta
    10501 aaatattaaa taataaacca taaagaattc ctttatttaa atcactagca tcaacatctt
    10561 taccccaatc atagtgaaca ggatattcag ctgcttccca tagaggagat ccttcttcat
    10621 tagataaaca aatagtcatt gctccaaatt ctcttgcttt ttttgttgct tctacagttt
    10681 ctggtgttgt gccagaatgg gaacaagtga taactaaaga attttcagat aatccttttg
    10741 gtatagcata gttaaattcg ttagcagtat aaacatgaca aggtacagtt aattctttat
    10801 caaatagata ttgaccagcc attaaaacgg cttgtgaacc cccacatgct gtaaaatata
    10861 catgatcaat tgtcttttcc tttaacgctg ccattgctgt ttcaatctgt tctttgtgta
    10921 gttgtctcat ttctttatcc ctcactctaa taagtattat aaagtcatat aactttacaa
    10981 tacctattat ctatgaaatt gctttatttt gcaatactat ttttcaaaaa aattttttta
    11041 taacaatttt atataataaa atgccagact gtagacaaag tccattttat ggatgatgtc
    11101 tacagtcttt tcttttataa tagatttatg aaaacgaatg caaggagtga tagctatgat
    11161 gtctaaaaac aatacgaatg gtagaaatca atttgcgatg cttacgattg atgatctagt
    11221 tcctcaagat catctcgttc gaaagattga tgcc
//
LOCUS       DAFEML010000070        11253 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFEML010000070
VERSION     DAFEML010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.072"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP468_002252"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP468_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL2081753.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP468_002253"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP468_002253"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL2081754.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LP468_002254"
     CDS             complement(2169..2906)
                     /locus_tag="LP468_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2081755.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LP468_002255"
     CDS             complement(2997..3524)
                     /locus_tag="LP468_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081756.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LP468_002256"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LP468_002256"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL2081757.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LP468_002257"
     CDS             complement(4401..4886)
                     /locus_tag="LP468_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL2081758.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LP468_002258"
     CDS             complement(5039..5236)
                     /locus_tag="LP468_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081759.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP468_002259"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP468_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL2081760.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP468_002260"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP468_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL2081761.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LP468_002261"
     CDS             9211..9423
                     /locus_tag="LP468_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL2081762.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LP468_002262"
     CDS             9425..11104
                     /locus_tag="LP468_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2081763.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAFEML010000071        11046 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFEML010000071
VERSION     DAFEML010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.073"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            3..523
                     /locus_tag="LP468_002263"
                     /pseudo
     CDS             3..523
                     /locus_tag="LP468_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(425..1141)
                     /locus_tag="LP468_002264"
     CDS             complement(425..1141)
                     /locus_tag="LP468_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL2081764.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1265..1450)
                     /locus_tag="LP468_002265"
     CDS             complement(1265..1450)
                     /locus_tag="LP468_002265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081765.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            1677..2950
                     /locus_tag="LP468_002266"
                     /pseudo
     CDS             1677..2950
                     /locus_tag="LP468_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3057..4088)
                     /locus_tag="LP468_002267"
     CDS             complement(3057..4088)
                     /locus_tag="LP468_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081766.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(4095..4925)
                     /locus_tag="LP468_002268"
     CDS             complement(4095..4925)
                     /locus_tag="LP468_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081767.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4922..5737)
                     /locus_tag="LP468_002269"
     CDS             complement(4922..5737)
                     /locus_tag="LP468_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2081768.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5734..6558)
                     /locus_tag="LP468_002270"
     CDS             complement(5734..6558)
                     /locus_tag="LP468_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL2081769.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6548..7648)
                     /locus_tag="LP468_002271"
     CDS             complement(6548..7648)
                     /locus_tag="LP468_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2081770.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7826..8611
                     /locus_tag="LP468_002272"
     CDS             7826..8611
                     /locus_tag="LP468_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL2081771.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8644..9027
                     /locus_tag="LP468_002273"
     CDS             8644..9027
                     /locus_tag="LP468_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2081772.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            9103..9234
                     /locus_tag="LP468_002274"
     CDS             9103..9234
                     /locus_tag="LP468_002274"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2081773.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            9203..9439
                     /locus_tag="LP468_002275"
     CDS             9203..9439
                     /locus_tag="LP468_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2081774.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(9517..10488)
                     /locus_tag="LP468_002276"
     CDS             complement(9517..10488)
                     /locus_tag="LP468_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL2081775.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3295 a         2554 c         2111 g         3086 t
ORIGIN      
        1 ctatggataa tcatactaga aaattactcg gattaacaga taaacattta ttttttgatg
       61 aagaatggct gattgaaaaa gaatataaag gcgttcaagc gcagtttatt aaagggagat
      121 tggatgactc accttcccat tgtgaacact gtggatcgat tcgtattatc cgcaacggtt
      181 cctatacgac acgtactcag atgttgaaag tcaaagaaaa gttgactatt ttagaattaa
      241 aacgtacccg ttttctatgc tatgattgtg ggcagacctt ttctgcgaaa acggacttag
      301 ttgatgaaca tcatcaacta acaaaggaac tgaagcaggc gattctcata gaactgtacg
      361 aaaatcaatc acgtaatctg aaaatcagaa gaagtaccgt cggctcaagc gatattggaa
      421 actcttactc aaagattcca cgacattgga gccgctcaaa cggcattatc atcgactgtt
      481 taaacgacca attagtcaaa cagaaatcgt cgatgaaccg ttgtgcacaa tggtgtcctg
      541 aacgtacagc gacaccttcc atatccagag cagtcgccac atcacgggga tggatgccat
      601 ccaaattaaa agcaaccacg ccagtatgat gttcaggatc ttgcggtccg taaatggtga
      661 taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac cagttcttgc tcataacgat
      721 gaatattctc cataccaatc tcattcaagt aatcgattgc tcctgcaatg ttcggagtac
      781 cagcttcaaa tttccatggc agctctttcc atgaactatc gtaaagattg acaaaatcta
      841 tcatttcacc gccgaattcg actggctcca tttgttctaa caattgacgt ttgccatata
      901 atacaccgat tcctgtcggc ccgcacattt tatgcccgct aaaggcgaaa aaatctgcat
      961 ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg ggcaccgact ggactatcct
     1021 caactacaac agcctgttca accctcagcc gtttcaagca caacaaataa ccttctggat
     1081 ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga atcaattttt tccttaatca
     1141 tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc agaattgaga ctactccgat
     1201 tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat ccactggtct cccaaccgct
     1261 tgacttatcc cttcataaaa ggacagttct gctgccgtcc caacaccttg ttgatagtct
     1321 gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg cttcagtaaa tagtgatgaa
     1381 tactctcgta aaacatccat tcactgtcaa tcatcgtccc atcaaaatca aaaataagtg
     1441 ctttggtcat cttctttccc ccttacccaa aacaagcaaa agctgtgtcc tgctctctct
     1501 acagtatcag cataaaaact gccgtctgaa aagtcaaagg tgaaagaaat gtggcgctat
     1561 aatttctagg actgatagta aatcattcta tcagtccttt tgagcataaa aaaacaaaac
     1621 atacagaagc tccgttagaa ttgaatcacc acaacacaat caaaggagcg ttctgtatgc
     1681 ctgatcttca tcttatcaaa ctattactag gaatcaaaga tggaaacatt caaatcactc
     1741 atgtcgagaa gaaaaaaata cattcaatca acagtatcgt tgtttctgcc acgctcatta
     1801 aaacgattca gccctgtcct cagtgtaaac aggtgaatca acatgggctg atcgttaaga
     1861 acggaaagaa aaaatcgctg gtccttctca ataagtgtgc gaatcaacgg acttatcttg
     1921 ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac ctattttacg gcgaatacct
     1981 acattgttga aaaaaactgt tttatcgcca aacaagtaca ttataaaata ttggaggaat
     2041 tgactgaaaa acaagcaatg acgacgattt ctaaacattg cggcgtttct tggtcaaccg
     2101 tttcgcgaac actcgcttct ctgctcccca tgacaaacgt gaaaataaat tggttgcctc
     2161 gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca agtcggtccc tattcttttt
     2221 cttgtatgga tggcgatact gggaaattac tggatattct tccttcacgt aagaagaaag
     2281 atctcatttc ttattttatg caatttgaac gacgtgcacg tttaaacgta aaaatactcg
     2341 taacagatat gaacgcctct tatgctttgc tgataaaaga gtgctttcct catgccaaac
     2401 tcgttgtgga tcgctttcac atcgtcaagc acctcattcg cagttttaag gatatttgac
     2461 tatgagtcat gaaaagcttc gaccgaaacg atccaataca agccaaacac tatcgacaag
     2521 tgaaggcttt atctcgactt ctgatcaaac gacaggacac gcttgtttat gataaatgga
     2581 caaaatggcg taattttggt tgggcctatt taaccgaaag tgaagtcgta gaacgtctac
     2641 tttctacttc tgatgaacta cgaatagctt atgcttacta tcaagaaatt cttcaagctt
     2701 tttatgacaa agaagcggac atcttctttc agcttgtaaa aacaatgccc aagtcggttc
     2761 caagagaact gcatcatata aaaaaagcgt ttataaacta tgaatccggc attcgtttag
     2821 ccttagagtt gccttactca aatggcaaaa tagaaaatct gcatacccac atcaaagcat
     2881 tgaaacgaat agcttacggg ttaggatgag aaccagaatt ttcttaatca atcatctgat
     2941 cacttattaa acataaaaaa acatctaaag cagaaaatca attctacctt agatgttctt
     3001 atatcactct atcagtccta tttgacaaag agccagaaat gtttgccgac tatacactag
     3061 ctttgttgtg caaaatgctg agtatcaatt tccacaggga ttgctagaat atctttcagc
     3121 tgaatgtata aggcatcgct aattttctct tcccgatcgt tcaaccgatc cactaaaatt
     3181 tctttgccct ccagcgtttg aaaaacatac cgttgaatgt tgcctaaaat aaatgattcc
     3241 ttccatagaa ccggaatctt aaccccctga ggaaccggtt caaattgaat cagctccggt
     3301 cttaaataat aaatgcagcg attgccctta gcggaaaact cgtgggtata ctgattcagc
     3361 tcataccatt cgaaacgatt atagttgccg ataaattccg caacaaatcg gctctgagga
     3421 ttctgataca attccttcga ggtggaaacc tgagccaccc gcccagcttc catcacaaaa
     3481 atccgatcac tgattcgcat cgcctcttct tggtcatgag tcacaaaaat catcgtcatc
     3541 cctagcgatt gctggatagc gcgcaaatcc cgctgcagct gttttctaat tcgggcatcc
     3601 aaagcactta atggctcatc cagcagcagg actttcggtt cagtgaccaa tgagcgagcc
     3661 agtgccaccc gttgtcgttg accgccagaa agaaactgga catttttatc tgcctgctcc
     3721 gtcatatcca ccaatgatag catctcaaaa accttttcct gaatcacctc aggactcagc
     3781 ttctttacct tcaaaccaaa ggctacattt tcaaaaacag tcatagttgg aaacaatgca
     3841 tactgttgaa aaacaaagcc gatattgcga tccttcgtag gcttatcggc aatattctca
     3901 ttgtccagca caatctcacc gctctttggt tgttccaatc ccgtgataca gcgcagcaac
     3961 gtagactttc cgcacccgct gggacctagt aaagtaacca gctcaccctt ttcaatctga
     4021 atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca gattgagatc atgtatttct
     4081 aaaaacattt tccgtcacaa ctcctttaag ggcttctttt tcgactgctt ctcttccctc
     4141 gtctgcttaa gggacagctg ttgcttttgt cgataagtca gcataaaggt agttaaagca
     4201 attcccacca taaacagcaa atacaaaacc atcacagcgc tagccaaatg gccgttttcg
     4261 ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc gaccgccaat caacaggttc
     4321 gtcagcatgt actccccaaa aaccgaagaa aaaatcatca gagaaactag ggtcacaccg
     4381 atacggatgt ttggaaacag cacctggata ataatcgtag acatcggggc gcccaaggtt
     4441 tctgctgcat ccactaattc cttcagatta attaagcgca tctggttgtt aagactaaga
     4501 tagacaatcg gcaacgccgt aataaacaat gcacctacca acactacaaa cattgggata
     4561 ccagtttcag catacgttcg aagcaaagcc gttaccaaaa tcactcctgg taaagcatac
     4621 ggcagcagga gcagcttttc cagccaacga ttcaaacgag ggaaatacaa atgaatccaa
     4681 ataatggtgg gaatcatcaa caacagaatc gtcaccaaga ccacacctgc taataaaagt
     4741 gagcgaccca ccgcagcaat aaattccctg tccgtcagca gctgttggaa ccattgcaag
     4801 gtaaaatcac taggtaaaag cgattttgac catttagtgg agctggcata caaaatcgtt
     4861 ccaataatcg gcagcaagta atacaggaca aagcagaaca aaatcggttt tattaacttt
     4921 ttcacgtctg caccaccttg cctttctttt gaataatcaa cattgccgtt accagcagga
     4981 cacctaaagc gactgccaac gcactgccta aattaggctt ggcgaacaca tctcccgaca
     5041 ctaaagccgc aattcgaatc gttaaaagat ttacattact gctggtcagg gcatacgctg
     5101 tttcataggt ccccatgcca ttagcaaata agatgacaaa ggtgctggca atcgatggtc
     5161 gcaaaaaagg caaagccacc ttgaaccaag catacgctga tgaagcgccc agcaattgtg
     5221 cggactccag ccattccttt ttcacttcct tcatgctggg atacaaaaac aagaccccta
     5281 acggaatttg gaaataggta tacgtgatgg tcaatcccca ccaagaatac aaattgaagt
     5341 ccgctagaaa tggcaaaatc attttcagca cacctacatt ccccaacaaa ataataaaag
     5401 agaatgccag cggaatccca gcaaaattag ctgccaaatt ggaaacaaag gtgattttct
     5461 cctgcaattt agtcgataga ttcattaagc ataaacataa aataaacgtc ccgattaacc
     5521 caatcacact ggagctgaca gcaatcagta cgctgttaac aaaggcctgt gtgtaatatt
     5581 tgttgctgaa aatatcactg taattggcca atgtccactg gttagttaaa tcactgtgca
     5641 agctgcacag aaccataaaa agcagcggca gcagtaaaaa tgcacagaag ataaaggagg
     5701 caggaaccag aaccaagcgt tttttcatct ctttcatccc ctcatcaatt cttgaatgtc
     5761 ctgcattttc tctgacggtg caattcctaa taaccagcaa aacaatggag ccgccagcag
     5821 ctgtggtaca gtttgttcct tcagcttttg gcgtttattt gaaatcaaat aaaaaggaac
     5881 ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc gcatccatcc cgtgatccgc
     5941 agtcaccacg acttgataac ctttttgcag ccattcagga aggtaaatag ccaataatct
     6001 gtccgcctga ttaaccgctg ctgcatattc atgagaatcg gcggtaaatt tgtgaccgac
     6061 atcatcaata ttcatcgaat gtacgaccaa aaagtctggc tgatactgat tcactaaata
     6121 atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc tcactataaa agatgccatg
     6181 ctgaatcagt cgctcctcct gatgctggat gcgatcaacc aaacgattat agggggcttg
     6241 attgtacaac tcgctgtacc agtggtaagc ggcggctcct gtttttccgc cagcttcctt
     6301 aactaattca aacagcgacc actctttgga tcgctgagca tggtaattac tatagatgcc
     6361 attttcatag gctggaacgc cggtcatcag tacttcgtat aacggacgtg aattgctggg
     6421 cagctcactt tttaccttca ataagcttgc ttgctggtgc tcaactaaat gattcatgaa
     6481 cccaagctgg gcgacggctg tgtcgtagcg acagccgtct agtataacta caatcagttt
     6541 gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca aagctctgga agctctacag
     6601 aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc cgcttcataa gcatcctccg
     6661 gcagtaattt ttcagctact tctttaggca gctctacctt gcgaataggt cgcgcatagc
     6721 cctttgccaa attgatttgc ccttcatcag ataaaatata ttcccgtgct agctttgccg
     6781 cattgggatg aggggcattt ttattgatta aggttgtata cccgctaatg atggagccgt
     6841 ctgttggcac agttacctca aaacgctcgg agtcaatttg gtcacgataa tttagtccat
     6901 tgaagtccca aacaactgcc acatcgattt cacctttttc aagatttgct acgctggcat
     6961 caacggtgga caaacggcct ttttctgcca tttttttgta gtaattcaga cctggctgaa
     7021 tatccttttc gtcacctccg ttggcaatcg ccgcagccaa tacagcaaat tgtgcttggt
     7081 tggcaatcgt cacatccccc acgctaactt gatagtcacc ctcttgcagc tccttccagc
     7141 tagtcggtgc ttgcttcaca ttctctttat cggtgataaa ggaaatggtt cccgtatagc
     7201 ttaacaacca atccccatca tcatcctttg cccaatccgg aatttcctcc caatagttgg
     7261 tcttataagg taaggttaac tctttgcttt cagccaacgg accgaagctg ataccgacat
     7321 caccaatatc ggcggttcca ttttttcctt ctgattcaaa cttagccaat tcttctgcac
     7381 tggacatatc cgtatccacg tgacttaagc cgtattcttt ttcaaggtcg ttccaagtgc
     7441 ctacccaatt tgcccaagta tccggcattc ccaagctggc aatctctcct tcttccttgg
     7501 ctttttctat aatcgtatct aaagagtcgt ctgccgcagc cgattgcttc gttgcttcac
     7561 ctgagccgca gcctgtcagc aggatactta ctgttgctgc acaaaataaa ccgatagtca
     7621 tgttacgaat tttttcattc attttcattc attcttctcc cctttcgata attccattct
     7681 aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg tttcatgaac aatgtaaagg
     7741 ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc ttctaaagct tttgcggtat
     7801 gatagtagaa aaaaggaggc tccctatgca gtattatgat cagcatctcc acacgtattt
     7861 ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc tatcagccgg agtttttcgt
     7921 ttctacggat cactttgatt taaacaatcc atctaccgga aaagatgaca ttccggatta
     7981 tccagcctat ataaacaaac tggactcttt aaaagaaacc tattccacca aatttctgcg
     8041 aggtatcgag attggcgttg ttccaggaca agaagagcgg atcgtggatt acctcgctca
     8101 gcatccttat gatttaaagc tggtaagtat tcatcaaaat ggccgctttg attatatgga
     8161 cgatgtggtt ttaaccaaag atcccattca aactaccaag gaatattttg atcagatgtt
     8221 gcaggtcttg acggattttc cagaaggaga tattttgact cactttgatt atggattacg
     8281 ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt gaggctcagc tgctaacgat
     8341 tttcaaaaag gttgttgaac gagaattggc gatggagtta aatgccaaga gcttcttgaa
     8401 atacggcaac gaagaccttt accgttatgc cgttcctttg tatcaaagtg tcggcggaaa
     8461 gctctttacc ttaggctcgg atgctcatgt tgccgaagat tatcagctgg gctttaaaaa
     8521 aatgagtcag ctgttggcag actgtcaggt agaaaagttg ctagtcattc aaggaaaaga
     8581 acgccgcctg acgccgctgc cgattttgtg attcctatat aatagaagaa agtggtgaaa
     8641 aaaatgagca acctgtggga ctacaatcaa gaggcaccca tccattattt aattgcgcga
     8701 cattgggatg cgttgaaaat tgaggcggtt tgccgatcct tgttagcagc cgttccaaaa
     8761 caacaactgg aaaatttttt ggtggctgac agcttgcagc gggaaaaagt tcaggcttat
     8821 tttgcagcct ttaaagatca gcctttggaa tatttgcatg cgcagtttca tcttttttat
     8881 caagtagccg ccccagatga ctacaacgat ttacgaggac agctgcaatt gacctttcaa
     8941 gcggatgaaa ccgcctatac cgttttattg ggaatggctc gccttggtga tcaggcgaag
     9001 gtcgagtggc ggattttcga tatttgatgg caggatcaag gcgtttcagt tgcaaacctt
     9061 cctctctttc aattagaaaa accgcagcag gaagaagttt gtgtgctggt caccgatgct
     9121 ggtgaaattc gtctccgctt atttcctgac caagctcccc tggctgtagc caactggcgc
     9181 tccctagctg agcaaggcgt ttatgacaac acacctttcg gctcgtgtca ttaaggaatt
     9241 tgttattcaa ggtggcgctt tggatggttc tggtgatgaa gctgtttcca gctatgaggg
     9301 ctttttcgct gatgaagtgc atcgcggact ttatcatttt aatggcgcct tggccttagg
     9361 ggaccacggc ccccacacca acggcaacca gttttttatt gtgcaaaaca caaaggcgca
     9421 ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg gaggactacc ggagctggat
     9481 ggtcgttata ctgtttttgg acaggtatac caagggttag aaatcgtagc agcgatcgca
     9541 gctcagccga caaacagtga agatgtaccg attgagccag tgttcattcg acaaattaac
     9601 ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc aaaagctcta ttcttgagct
     9661 ggctgcagct agtgagtgtc tttcatttat ccataagata aagcttggat tcaataaata
     9721 aataaatgtt ttggttaaag ctgtgaccag caaatgagga accgtgcgag ccagttgatc
     9781 tgccaatgca aacatttctt taggtgaagg cgctggcgtg tctgccaacg gatactccag
     9841 tcccaatgct tggtaaccgt gcataccata gcagtggtac ggtagtaatt ctaacggtac
     9901 gaaccgatca agatctgcca caaaacaagc aatcgtcagc agctcggtca ggttcatatt
     9961 gatacctgga accacaggaa ctcgaattcg cacttcgcag ttaggatact caattaaaaa
    10021 gcgacgaata ttcttcaaaa tttgttggtt atctaagccg gtccattgtt tgtggagctt
    10081 gctggtaaac atttttacat ccacaaacaa tgtatccaca tagggagcta ccttttggat
    10141 ttcattataa gcaccacaaa agctggtttc cagtacggta ttgattccaa tgtatttcga
    10201 tttttgcaaa atttctttag caaaatccgc ctgaaccagt gcctcgcctc cgctaatggt
    10261 cactccgcca tccgagtgaa agtaaaaaac agcatccttc tcaatctcat ccattacctc
    10321 ttcagcggtc atggtctggc caaatccttt ttcaatctgc ttgctttgtg attcgggaat
    10381 cgaacaccag gcacagcgta atgggcagcc ctttaaataa acaacggtcc gtaaaccagc
    10441 accatcatgt agagaaccct gttctattct taatactgtt ccttccatat agatttttga
    10501 attacacact agtttaaact aaaacacaca aggaaaaact taccatttaa tcataaaatt
    10561 agctcatata aatatactag gatgtaaaat agactggtca aaatctggtc aaaaaagagg
    10621 actaatacag gtagtcctct tttttgttat tttaatattc taaatcattt tttattggtt
    10681 tattccctta ttcgatgtag actcaaatca ctatatcact agatatcaaa cggcgtcata
    10741 cggaatcaaa aacatcaaat ttgacctgtt aaatggtcat tgaataacat tcaaaatcaa
    10801 taaaacggag tcagacacgg agtcaaaaac gctgagagta aaaaatatat acagccttgt
    10861 aggtaaagta ccacagggct gtatattttt tatttcagat taccttaaat gattccattt
    10921 actttttatc tcattttttc ctactagtta gtatcaaata ctctcctatt ttctcaataa
    10981 actatttttg gatacatggt atctgaaaca gctaaaacct tgtcattaca gcaaaaaatc
    11041 acgtta
//
LOCUS       DAFEML010000072        10640 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFEML010000072
VERSION     DAFEML010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.074"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="LP468_002277"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="LP468_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL2081776.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="LP468_002278"
     CDS             808..1242
                     /locus_tag="LP468_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL2081777.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="LP468_002279"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="LP468_002279"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL2081778.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="LP468_002280"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="LP468_002280"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL2081779.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="LP468_002281"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="LP468_002281"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL2081780.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="LP468_002282"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="LP468_002282"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL2081781.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="LP468_002283"
     CDS             9513..10439
                     /locus_tag="LP468_002283"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL2081782.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
BASE COUNT         3763 a         1838 c         2283 g         2756 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttcg
    10561 gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa taattggaga tcaagtggat
    10621 cagttcctct tgatcttttt
//
LOCUS       DAFEML010000073        10493 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFEML010000073
VERSION     DAFEML010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.075"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..357)
                     /locus_tag="LP468_002284"
     CDS             complement(<1..357)
                     /locus_tag="LP468_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL2081783.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLG"
     gene            complement(709..1068)
                     /gene="rplT"
                     /locus_tag="LP468_002285"
     CDS             complement(709..1068)
                     /gene="rplT"
                     /locus_tag="LP468_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL2081784.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1121..1321)
                     /gene="rpmI"
                     /locus_tag="LP468_002286"
     CDS             complement(1121..1321)
                     /gene="rpmI"
                     /locus_tag="LP468_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL2081785.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1393..1917)
                     /gene="infC"
                     /locus_tag="LP468_002287"
     CDS             complement(1393..1917)
                     /gene="infC"
                     /locus_tag="LP468_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL2081786.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1961..2086)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2237..2869
                     /locus_tag="LP468_002288"
     CDS             2237..2869
                     /locus_tag="LP468_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2081787.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2871..3776)
                     /locus_tag="LP468_002289"
     CDS             complement(2871..3776)
                     /locus_tag="LP468_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2081788.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3861..4520)
                     /locus_tag="LP468_002290"
     CDS             complement(3861..4520)
                     /locus_tag="LP468_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2081789.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4836..5780
                     /gene="mvk"
                     /locus_tag="LP468_002291"
     CDS             4836..5780
                     /gene="mvk"
                     /locus_tag="LP468_002291"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL2081790.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5773..6750
                     /gene="mvaD"
                     /locus_tag="LP468_002292"
     CDS             5773..6750
                     /gene="mvaD"
                     /locus_tag="LP468_002292"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL2081791.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6763..7848
                     /locus_tag="LP468_002293"
     CDS             6763..7848
                     /locus_tag="LP468_002293"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL2081792.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7845..8909
                     /locus_tag="LP468_002294"
     CDS             7845..8909
                     /locus_tag="LP468_002294"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL2081793.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9158..9961)
                     /locus_tag="LP468_002295"
     CDS             complement(9158..9961)
                     /locus_tag="LP468_002295"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL2081794.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9981..10286)
                     /gene="kduI"
                     /locus_tag="LP468_002296"
                     /pseudo
     CDS             complement(9981..10286)
                     /gene="kduI"
                     /locus_tag="LP468_002296"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10268..>10493)
                     /locus_tag="LP468_002297"
     CDS             complement(10268..>10493)
                     /locus_tag="LP468_002297"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL2081795.1"
                     /translation="LWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLI
                     VIIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3104 a         2220 c         2008 g         3161 t
ORIGIN      
        1 acctaatgac atcaagatcg gcaacacaat aactgcaata gaaatcactg gtccgattcc
       61 tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg tgattcttgg
      121 cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc cgctatctac
      181 tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt tggcgtactc
      241 agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc cttccatcgc
      301 cgagtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag tagccatgat
      361 gacaaaagcc gaccatcaag ttgtagcctt ttacacagta ccagaccatg aaaaagaatg
      421 agataactaa caaaatacca ataataatat cactcatgtt attcctccgt ccattttgtt
      481 tttctgataa gcaaactaat atatcagtca aactcattct aacttatgta gttagcgctt
      541 tcattaaagg atgaccataa atgttcagtt ttcaattaaa aaaccttaat tatgttattt
      601 tagacttata cgttattgtc ctgtttcatt tgatggagga ttgtaaataa aaaaagagga
      661 aagaacataa cttttcgtta tcttctttcc tctttataat tgtttagctt atttagccaa
      721 agcttctttt gcttggtcag ccaatgcagt aaatgctgct gcatcgttaa cagccaagtc
      781 agctaacatt ttacggttga tgtcgatttc agcaactttc aaaccgtgca ttaattttga
      841 gtagctcaag ccattcatac gagctgctgc gttgatacga gcaatccaca atttacggaa
      901 gtcgcgtttc ttttgacgac gatcgcgata tgcgtagttg tatgaattca ttacttgttc
      961 ttttgctgtt ttaaataaag tgtgttttga accgtagtaa ccttttgcta attttagcac
     1021 tcttttacga cgtttacgag ttactgttcc acctttaaca cgtgccatgt ataattcctc
     1081 ctaataaaaa taaatcttca gattctgtta tttgtacttc ttatttcatt tttgctagtt
     1141 gttggcgaat acgtttgaag tcgccactag aaaccatgct tgctttacgc aattgacggc
     1201 gttgtttttt tgttttgccg tggaaacggt gacttgtaaa cgcgcggaag cgtttcaatc
     1261 cgcctttacc agtacgtttg aaacgttttg ctgatccgcg gtgtgttttt tgttttggca
     1321 tgactatatt tcctcctcaa aatctttcgt tatccgacta tcggctgtcc aacagccagt
     1381 tagtcattca aattacttac tgtcgttttt cggtgccagc gtcaagaaca tgctgcgtcc
     1441 gtccattttc gctttttgtt ccactgttgc aatatccgca gtttcttcag ctaagcgatt
     1501 caagactttt tgaccaattt ctttatgggt aatggcacgg cctttgaaac ggatagaagc
     1561 tttcacttta tcgccctttt ccaagaactt acgtgcatta cgaagttttg tattgaagtc
     1621 attcaagtcg atcgtaggac ttaagcgaac ttcttttaca ttgatcactt tttgtttttt
     1681 acgcgcttcg cggtctttct tttgttgttc gaaacggtat ttaccgtagt ccatgattcg
     1741 cgcaactggt ggtttcgcac caggggcaac taacacaaga tccaagtttg cttgttctgc
     1801 aatattcaat gcttctgctt ttgtcttaac tcctaattgc tcaccatctg aaccgatcaa
     1861 tcgtaactct cgtgcacgaa tgccgtcgtt aaccatcata tcctttgcta tggtcattca
     1921 cctccaaata ttatgagaga aagaaaagct taccgaataa acggcaataa aaaaacgagt
     1981 tctcttacag aacccgcgcg tacttcacct aatagaacca gtgaaaacta tctagcccag
     2041 tgacattatc aactaaggcg agaagcgggt gcttctgctt ttatttctca accattatag
     2101 tatagcaaaa actaatcttt ttgtcaatgt ttttcataca gtttgtcttc cttttctgaa
     2161 aatgattaga ttagcaggct ttctagcagt gattcccgct tctttgctat actaaagaaa
     2221 aacgaggtga acccacatga aaaaaatcga acctattcca ccttctcttc ctcttcttac
     2281 aaagggagag ttttatttag aagatgagga gatcttctct ggtcttctga tcaacggagg
     2341 taaccaaagc tatctcgatg ccaaaaatat ggtattaaga gagagtcata tccaaaaact
     2401 tacgatgcaa aaaacaggtt tacgtcattt tgaatgcagt aatgtcattt ttgaaaaatg
     2461 tgatttttcc aatctggagt ggattggtgg cagtttccac caagtcgtgt ttcatcaatg
     2521 taaattaaca ggtacgaatt ttgccgaaag ttatcttcga gactgtactt tcactgattg
     2581 tattgcttcg atggcttcct ttagtagtac aaacttgaaa gctgtctcct tcgatcattg
     2641 tcaattagaa gacagcgaat tttatgaggt cacttggaaa aacctttttt tgtctgacaa
     2701 tcagttaacc ggttcgaact ggtttcgaac ttctctgaag ggattagact ttacgactaa
     2761 tttcttcaca acaatcgctt tatctcaaga ttctttggcg ggactaatcg tcaatcaaga
     2821 gcaagcactt gtgatcgccc aagcccttgg tttgcagatc aaagactaga tcaacgaatc
     2881 cgccgccaca gtgcaataag catccaaata gataagacca aactgatgat caaggcgatt
     2941 tcccatccga aaacggaatg ggtaaagggt aactggagat tcattccgaa gaatcctgtc
     3001 acaatagttg gaacggtcaa gatcagcgac cagaccgtca aaaatttcat cgtgtcattc
     3061 aagttgttat tcagcaaatt attataagtg ccagagagct ggtctaaaat ctgcgaagct
     3121 aagttcgtca tttcaactgc ttgtcgtgct tcgatcagtg catcgtccaa ctcttctttt
     3181 tccttttctg acaacttgcg ataaatagcc agtgccttga tttgttctaa aagtactaca
     3241 ttttgttttg ttcctgtaac taagtaaacc aaaccgatct ctaaatctga aagttgcagc
     3301 agattcttgt tcgttgtttt ttctcttaat ttcagattaa gccgctgacg ttcactattc
     3361 acttcctcga ttaaaggaaa aaaggaatca gaaatcaaaa acaatgtacg aaacaataaa
     3421 ctgtatacac tcatgtctgg catccgttcc aaaagcgatc gaattagtcg aatcacgtac
     3481 tcggtattcg gcgtggtaaa tgtaaacaaa ccgtcttctt ttaaaataaa agcgatagga
     3541 ctagtttcat aatgattatc gactttttgc tggtgcggaa catttgatac aagcagtaac
     3601 gcttcatcaa aagaatcgta ctctacgcgc gcccgttcat ttttatctag agaataagtc
     3661 agcatctcgt cactaatgcc atattcttct tttaagtttt taacagctag cacatcgttt
     3721 tgctgtacat tgatccaaaa attacggtct tgattaaaat agtgtttttc ccgcatactc
     3781 tatcctcctg acatttgttt ccagtataaa gaaaaaagtc gctcaaataa aggtttaccc
     3841 tttatttgag caactgtaaa tcaaatggat actttggttt ggcgaatctc tgctaatttt
     3901 tcttcgatca ttttcaagac ttcttctttt gcttgaggat cttccacaaa attatagcgg
     3961 tctccatcga tttggatttt tggactttct ttgtattctt cataccattg atcataacgt
     4021 ctgttcaatt ctttgtaata atcgtataga cttgggtcaa aggacaattg ttcatacgaa
     4081 cgaccacgtt tttcgatacg ctctaacatc gtatcaaaag atacacgaat atgaactaat
     4141 aaatccggat gttttttatg ggcagcatag ggaagttctt ccatcatgtt ttccagcagt
     4201 tcatcataca cacaaacttc tgtttctgtt gctcttccta gatctgcatt tagatggaaa
     4261 agcagtgaat cttcataaat cgaacggtcc aatacattat tgtcatcttt cattgcttgt
     4321 ttgatgcttg caaaacgttt attcaaaaaa taaatttgca gcaaaaaagc atactgttca
     4381 gggtttgcat aaaataaggg caagacttca ttatcatcaa tcgattcata aaatgcctga
     4441 ctatcaaagt gttcagccat catttctgtt aaacttgatt ttccggcacc aattgtacct
     4501 gctaaaacga tcacgctcat ttacctccag ctcacttcat cactaaatat tgtgtttaac
     4561 tccaaccttt tttaaatata cccccaatat ctagtagtgt caattgtatt ttttctagtc
     4621 aaagaagaaa aaaagtcaaa aaattcttaa gaaaaaagtg ttttttcttt agaaaacgta
     4681 ttcttagttt tacttctgag atggttttag taaaataaag gaggaatgtt ttttgagacc
     4741 cttagtggac aaaaaaattc gtgaagcagc gcaactcgtt ttgggcgctt tattttttgc
     4801 ttaaaaatca cttttacgtg agaaggagtt agattatggc aaactatggc caaggagaat
     4861 caagcggaaa gatcatattg atgggcgagc acgcggttgt ttatggagaa ccagcgattg
     4921 cctttccttt ctatgcaaca aaagtcaccg cattccttga agagctggat gcaatggacg
     4981 atcaactggt ttcttcctac tattcaggaa atttagccga agctcctcat gcattaaaaa
     5041 atatcaaaaa attattcatt cacttaaaaa aacagcatga catccaaaaa aacttgcaac
     5101 tgaccattga aagcacgatt cctgctgaac gtggaatggg atcaagcgct gcagtcgcca
     5161 cagcagtcac tcgtgctttt tatgattact tagcatttcc tttgtctcgt gaaatactat
     5221 tagaaaatgt ccagctttcg gaaaaaatcg cccacggtaa tcctagtgga atcgatgcag
     5281 ccgctactag cagcttgcag ccgatttatt ttacaaaagg gcatcctttt gactactttt
     5341 ctttgaacat cgatgctttt ttgattgtcg ctgatacagg aatcaaagga caaacaagag
     5401 aagccgtcaa agatgtcgct cacctctttg aaacccagcc tcatgaaact ggacaaatga
     5461 tccaaaaatt aggatacttg acgaagcaag caaaacaagc aatcattgag aattcaccag
     5521 aaacgttggc acagacaatg gatgaatcac agtcacttct ggaaaagctg acaatcagca
     5581 atgattttct taatctattg atccaaacag caaaagatac cggggcattg ggtgccaaat
     5641 taactggcgg tggacgcggt ggctgtatga ttgcattagc acaaacaaaa acaaaagccc
     5701 aagaaatcag tcaagcactt gaagatgcgg gtgctgctga aacttggata caaggattag
     5761 gagtacatac ctatgtttaa aggcaaagca cgcgcatata ccaacattgc tctaatcaaa
     5821 tattggggta agaaaaatga agaactcatc cttccaatga acaacagcct ttcgttaaca
     5881 ttggatgcat tttatacaga gacagaagtc atcttttctg atagctatat ggtagatgaa
     5941 ttttatctag atggcacctt acaagacgaa aaagcaacaa aaaaagtcag tcagtttctt
     6001 gacctttttc gtaaagaagc cggcctctca ctaaaagctt cagtaatcag tcagaatttc
     6061 gttcctaccg cagctggatt agcctcctct gccagcgggc tagctgcttt agcaggagct
     6121 tgcaatactg ctcttaagct tggattagac gatctctctc tttcaagatt tgctcgacgc
     6181 gggtctggtt cagcttgccg aagtattttc ggtggtttcg ttgaatggga aaaaggccat
     6241 gacgacttaa gttcttacgc taagccagtc ccttccgatt ctttcgaaga cgatttagca
     6301 atggttttcg ttttgatcaa cgaccagaaa aaagaagtgt ccagcagaaa tgggatgcgt
     6361 cgaacagtcg aaacatccag tttttatcaa ggctggttag attccgttga aggggatcta
     6421 tatcaattga aacaagcaat caaaacaaaa gatttccaac ttctcggaga aacgatggaa
     6481 agaaacggac taaaaatgca tggaacgact ttagctgccc agcctccatt cacttactgg
     6541 tctcctgaca gcttaaaagc gatggatgcg gtgcggcaat tgagaaaaaa aggcattcca
     6601 tgctacttta cgatggatgc tggccctaat gtcaaagttt tagtggaaaa cagccattta
     6661 tctgaggtac aagaaacatt taccaaatta tttagcaaag aacaagtaat tactgcccat
     6721 gctggtccag gaattgcgat tattgaataa agggagattt ttatgattga agtatctgca
     6781 ccaggcaaac tctatattgc cggagaatat gcagttgttg aaacaggaca tccagcagtt
     6841 atcgctgcag tcgatcaatt cgtaacagtc actgtagaat ccgcacgaaa agtcggaagt
     6901 atccaatctg cacaatatag tgggatgcct gtacgttgga caagacgcaa cggagaatta
     6961 gttttagata ttcgggaaaa tccttttcat tatatccttg ctgctattcg tttgactgaa
     7021 aagtatgcac aagaaaaaaa cattctttta tccttttatg atctgaaagt aacaagtgag
     7081 ttagacagtt caaatggccg gaaatatgga ttgggttcta gcggtgccgt gaccgttgca
     7141 acggtcaaag ccttgaatgt tttttacgcg ttgaatttat ctcaattgga gattttcaag
     7201 attgcagcac tagccaattt agcagttcaa gataatggtt cctgcggcga catcgctgct
     7261 agctgttatg gtggctggat cgctttctca accttcgacc atccttggct ccaagaacaa
     7321 gaaactcagc attctatcag tgagttactt gccctggatt ggccaggtct atccattgag
     7381 ccattgattg ctcctgaaga tttacgttta ttgattggtt ggacgggtag ccctgcctct
     7441 acttctgatt tggtcgatca agttcaccgt tcgagagaag acaaaatggt ggcttatcag
     7501 cttttcttaa aaaacagtac agaatgtgtc aacgaaatga tcaaagggtt taaagaaaat
     7561 aatgtaacgt tgatccaaca gatgattcga aaaaaccgac aattactgca tgatttatct
     7621 gcaatcactg gggtcgtcat cgaaacgcct gctttgaaca aattgtgtaa tttagctgaa
     7681 cagtatgaag gagccgcaaa atcttctggt gcaggtggtg gcgattgcgg aatcgtaatt
     7741 gttgaccaga aatctggcat ccttccttta atgagtgcat gggaaaaagc agaaatcact
     7801 ccactgccgt tacatgtcta tagcgatcaa agaaaggaaa accgatgaat cgaaaagacg
     7861 aacatgtttc actagctaaa gcctttcatg ataaacaaaa aaacgaattt gacttcgtac
     7921 ggatcatcca taaccctttg ccgcaaatag cagtttctga tgtcgatcta agtacacagg
     7981 cagttgggtt tacactaagc agcccatttt atatcaatgc gatgactggc ggaagcgaaa
     8041 aaacaaaaaa aatcaaccaa gatcttgcaa tcgtcgcaag agaagcagat ttgatgattg
     8101 ccactggttc agtcagcgct gccttgaaag acccttcttt agccgatact tatacgatta
     8161 tgcgacaaga atatcctcac gggaaaatca ttgccaacat cggtgcaggg acttctgtcg
     8221 aaagagccca agaagctatc cgattgtttc acgcagatgc cttacagatt catttgaatg
     8281 cacctcaaga gttggttatg cctgagggag accgtgattt taccaattgg aaagtactta
     8341 ttcaagagac tcaaacagcc attgacgtcc ccctcatcgt aaaagaagtc ggttttggca
     8401 tgacaagaga aacgctcaat gatctagctg ctttaggagt tcatacagtt gatatcagcg
     8461 gtcgaagcgg aacaagcttc acccagatcg aaaacgcccg tcgctccaag cgggaactga
     8521 gttatttagc tgactggggg caatcgacag tctcttcatt gcttgaagca aatgaagcag
     8581 acacttctat ggaaatccta gcctccggag gtatccgcaa tgcctatgac atatttaaag
     8641 ccctttgtct cggcgcaaat gcagtgggta cttcaggaac cgtactgacg catctgatga
     8701 atcacggcgt agaagaaact attatactga tgaagcaatg gcaagaagag cttcgtctgc
     8761 tttatactat ggtcggcgca acgaataccg cggccctaca ccaacaatca ctgatctttt
     8821 ccggaccagt gaaggattgg tgcgaagcaa gagggatcga cttagtgaag tatggaagac
     8881 gcacagaaaa gagcgtggga caaaagtaaa gaacactttt atcccacgct ctaaacacgt
     8941 ataaacggcg gaagcaaaag caactccttc ggaaataagc tgaaattcac aaaaatttga
     9001 aaagcaattt tcgtgaattc cttcttattt cttggagtta aacgcttctg tcccagcctc
     9061 ttttttcgaa taaatgatgt ttaatcagct gtccttcggt attcgttcaa gccgctgatt
     9121 tcacaacctc tccactaaac ggtgtactaa agctctttta aggttgtttt ccgatatagg
     9181 caagtatgcc tccgtccaca tacaagacat ggccgttaac gaaatcagat gcgctagaag
     9241 ccaagaagac agatggtcca gccaaatcga ttggctcgcc ccagcgtgct gctggcgtac
     9301 gtccaacgat aaattgatcg aatggatgac gttcaccgtt ttcttgtgtt tcgcgtaatg
     9361 gagcagtttg cggtgtagca atataacctg gtccaattcc attacattgg atattgtatt
     9421 gaccgtattc agaagcgatg tttttcgtca gcatttttaa tccgcctttt gccgcagcat
     9481 aagcactgac cgtttcgcgt cctaattcac tcatcatgga gcagatattg atgattttac
     9541 cgccgccttt ttcgatcata tcccgaataa ctgcttttga aacgatgaat ggggcattta
     9601 aatccacgtc gattacttgg cggaagtctg ccgcatccat ttcgatcatc ggtgtccgtt
     9661 tgatgatccc tgcattgttg actagaatat caactgaacc tacatcttct ttgatctgtt
     9721 gaaccatcgc ttgaaccgct tcttcatcgg tcacatcgca gacataacct tttgcatcga
     9781 tgcctgcttc tttataatgc gctatacctt catcaactga ttcttgattc aagttattaa
     9841 atacgatttt tgctcctgct gtagctaaag agcgtgcaat ctcaaatcca ataccataga
     9901 cagcaccggt gactaatgct acttttccat ctaaacgaaa catatccata ctaaattcca
     9961 tcattttctc tcccttatgc ttattttaat tgatccattt gcaccatatc catgtctgta
    10021 taggtgatat tttctccgca cattgcccag atgaatgagt aattgcttgt acctacacct
    10081 gaatggatcg accagcttgg cgaaataatg gcttgttcat tgtctacgac taaatgtttt
    10141 gtttcatctg gtttgcccat catatggaac acacgtgtat cttcattggc ataatcaaaa
    10201 tagacataag cttccatacg acgttcatgt gtatgacaag gcatcgtatt ccaagcactt
    10261 cctggttcta aaatcgtata acccatttat aaatgacagc tatcgctgaa gcttctactg
    10321 ctgtaaatat ccccgtcaag ataccaccga taatgatgac aatcaataga aggctaggaa
    10381 tcgcctcttt tattattttt ccagcatgag ccatctgtcc tttttcgaca acagggtatt
    10441 tattcttttt agcaacgatg aatgctacta gcatgattcc tagcgcccac aaa
//
LOCUS       DAFEML010000074        10376 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFEML010000074
VERSION     DAFEML010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.076"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP468_002298"
     CDS             6..305
                     /locus_tag="LP468_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081796.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP468_002299"
     CDS             378..1739
                     /locus_tag="LP468_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL2081797.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP468_002300"
     CDS             1761..2021
                     /locus_tag="LP468_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081798.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP468_002301"
     CDS             2035..2787
                     /locus_tag="LP468_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL2081799.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP468_002302"
     CDS             complement(2881..3486)
                     /locus_tag="LP468_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2081800.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP468_002303"
     CDS             complement(3539..4513)
                     /locus_tag="LP468_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL2081801.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP468_002304"
     CDS             complement(4891..5610)
                     /locus_tag="LP468_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081802.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP468_002305"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP468_002305"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2081803.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP468_002306"
     CDS             7161..8558
                     /locus_tag="LP468_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2081804.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP468_002307"
     CDS             8639..9079
                     /locus_tag="LP468_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2081805.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP468_002308"
     CDS             9227..9553
                     /locus_tag="LP468_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2081806.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP468_002309"
     CDS             9554..10303
                     /locus_tag="LP468_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081807.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
BASE COUNT         3290 a         1832 c         2151 g         3103 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcccgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacag
//
LOCUS       DAFEML010000075        10226 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFEML010000075
VERSION     DAFEML010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.077"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            227..2392
                     /gene="acm"
                     /locus_tag="LP468_002310"
     CDS             227..2392
                     /gene="acm"
                     /locus_tag="LP468_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBL2081808.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2664..3149)
                     /locus_tag="LP468_002311"
     CDS             complement(2664..3149)
                     /locus_tag="LP468_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL2081809.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3239..3584
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3629..4270
                     /locus_tag="LP468_002312"
     CDS             3629..4270
                     /locus_tag="LP468_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2081810.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4289..4924
                     /locus_tag="LP468_002313"
     CDS             4289..4924
                     /locus_tag="LP468_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2081811.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4942..5757
                     /locus_tag="LP468_002314"
     CDS             4942..5757
                     /locus_tag="LP468_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2081812.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6076..7512
                     /locus_tag="LP468_002315"
     CDS             6076..7512
                     /locus_tag="LP468_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2081813.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAITEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7701..10148
                     /locus_tag="LP468_002316"
     CDS             7701..10148
                     /locus_tag="LP468_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL2081814.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
BASE COUNT         3576 a         1671 c         2203 g         2776 t
ORIGIN      
        1 agcaataagt aaaataaaat gaatatatgc gaaaaaataa tttacattag gaaaaacctt
       61 gtaaaaacag ttttttggca tatttatttt ttataaatat ttgtaaaata actatcaatt
      121 ttttagttaa aagattggaa atgagtgggg gaggaattga agaaaggatt tttgagagat
      181 gatatagtag gttttatttt tagttaaaat aggggagata gaaaaaatga aaaagtgtag
      241 aaatattatt ttatcaatgt tatttattat tactaatata acatcactga ttcctgttca
      301 tgtctatgcg gatgcaggca gagatatcag cagtaatgtc acttcgttga ccgtggaccc
      361 aacgaatatt acagatggag gaaacataaa agtaaaattc tcgtttgacg aaaaaaaaca
      421 aaatatccaa ccaggtgatt atctttggat caattggcca agtgaaggaa atattcgcgg
      481 tgaaggattc caaaaagaaa tcccattaat gattgaaaat aaaaatgttg gaactttaac
      541 ggtcagaaaa gattctgcgc aggttgtgtt taatgaaaat attaaaaacc tagactcagt
      601 agaaggttgg gggcaatttg agatacaggc cagaaacgta accgataccg gtgaagaaaa
      661 tacgggacca ttcaccgtga cgagcggtga taaaacagct actgtaaatg tgacaaagcc
      721 agcttctggt tcttcttcta gcgtttttta ttataaaaca ggagacatgc tacctgaaga
      781 tactaagcac attcgatggt ttttgaatat taacaataac ggcacttatg ttgaacaacc
      841 agttaaaatc agtgatgaaa tccaaagtgg acaaagatta gatccaagta cgtttgaaat
      901 taatcaaata cacttaggtg aacagaaggt ttatagagga gaagagggaa tccaacaatt
      961 tttacaagat ttccccagcg ctacatttaa tttttcagta actgataatt acattgaaat
     1021 aactatacca aaaaactttg tcaatcttag gaaaataatg gtgagttata agacgatcat
     1081 agaaaaccca gaacaaataa attttgagaa tcattcggaa gcttggttta aagaatttaa
     1141 taaacctgct gttgatggag aaagtttcaa tcatacagtt aaaaatattt cagcttctgg
     1201 tggagtcaac ggtacagtta gaggcgaatt gaagattttc aaatatatca atgacacaga
     1261 gattggtatc ccaaatgtga ctttcgaatt aagacgagca gatgaacagc ctattcaagg
     1321 acagtctagt atcctgttga cttcgaatga acagggagaa gctagtatca aaggcctgca
     1381 agtaggagac tatgttgtaa aagaaaaaga agcacccaat tggattgatt ttgatccact
     1441 aagttcaaat gaactcaaat tctccataaa cgaaaatgat acagagggag tcagtttacc
     1501 tatttataac aagaaaaagg ttacgaacat cacagcaact aaaatttgga acggtggaac
     1561 cactccaaga ccgagtattt attttaaatt attcagagca agtacaaaca attgggaacc
     1621 agttcctgat gcagaaacaa aacgattaga caatggaata acttcagtga cttgggaaga
     1681 tatccaacag tatgatgata gtggaaacga atatacgttt aaagtgcaag aagtagatca
     1741 aaacggaaat gattatgtcc cttcaggtta tcaaaaaatt gaaaacgggc tagtcgttac
     1801 aaatgagaat aaagaagtca tttcagtctc aggacaaaaa acatgggaag acaatgagaa
     1861 ccaagacggc aaacgaccga cgacgatcac agtaaatcta ttagccgacg gtcaaccgat
     1921 ccaacacaaa gaagtaagtg aaaaagatga ttggcgctat cgtttcacaa atctgccaaa
     1981 atacagagac gggcaagaaa tcatctatac tgtaacggaa gacaacgtgc ccgaatacag
     2041 tacgacgatt gacgggtata acatcaaaaa cagttataca ccggaaaaaa caaatatatc
     2101 tataccaggt agccatataa caccgtggaa aaattttcca gagaagacag agagagagaa
     2161 aattagaaat ctattctctc aaaaattgca aatatttgct catacaggag aatccagcga
     2221 acaaagaagc aattatatta gtaagagagc tgtacctaaa cagataacaa ataaatcaaa
     2281 aagcattctt cctaaaacaa gtagtaaaaa atctagtttt gctgtaatca ttggtttatt
     2341 gatagtaact atctgtgctg ggatattctt acaaaaatat aaaaaagttt agttagaata
     2401 taatattttt tgttaaatat gactgaaatc aaaagaataa aattccgatt tataatcgaa
     2461 aaaagaagca tttttatata tgcttctttt ttcgtagaat caataaatat ggatttggct
     2521 aactatggaa gaatactcgt attagttttc agcgttcata ctagttgtta cattgtttga
     2581 ttggccaaaa gaatttctga tatattttgt gctaaataaa gaaaaagacg cttgaattgg
     2641 gaaataagaa aactactcta tcattacaaa ttttcataaa ctggcagatg ttctaagtaa
     2701 acaagtatct tttcaaagtc ggaaaaatcc ataatcaacg tagtggtatt gatatttgga
     2761 tgaaagccta cggtatcttg acgatcaata gcagcatcga tcacgacttg gatttttttc
     2821 tctttgtcgt gcatcaatgc taatggagtc actgtacctg ctggaacgcc taggaggtca
     2881 ggaagctgtt cttcagaaac aaaagataag cgcttttctt ttaattgttc agctagttgt
     2941 tttaaatcgg cgtgcttttc atcaggcaag atgacaagat agatttgttt tccttttctt
     3001 gatttcaata atagattttt tacttgcgga ccaggtaggg aaaaagggac atttttgact
     3061 gacgtaatcg caggatgatc gactttttga aaagagatac ccagtttttt tagtagttca
     3121 taagcttctt gttcggttgc acgactcatc gcgcatcacc ctcctttttt tattagtgta
     3181 tcataaaaaa gagttgacaa atgaaaaata atcatgtaaa ttacacgtaa agttaaaaca
     3241 aatgacatcg aaaagaagag tagccgttag gtgtttttag agagtctctg gttggtggaa
     3301 agaggcagca gttaaccgtg aaacacatct tggagtcgat tttctgaagc gtatagtagg
     3361 aaaatccggg gagcccgtta cagctgcggt cgttgctaga tgaccagata aggctggctt
     3421 ttccgtgagg agtcggtaaa aaaaggtgga accacgtgat taacgtcctt tgatcttcgg
     3481 atcaaaggac tttttgtttt catctgaacg gcaacgactg tgtgaggttt tttctgcaag
     3541 gaaaaaataa acagaggtgg aaccacgtat aatacgtcct cttggcattt gccaagagga
     3601 tttttttatt ttaaaggagg aaaagaagat ggagtatttg attgaagtta tgccgcaatt
     3661 attagtagga gcactcacaa cattgaaatt atttttattt accttgattg gctcattacc
     3721 attagggatt gttttagcat taggattgtc tttgcatttt aagccgctac gctacttgct
     3781 tcaaacatat gtatgggtta tgcggggaac accgctgttg ttgcaactga tttttatttt
     3841 ttatgggttg ccgacgattg ggatcgtttt tgatcgtttc gaagcagcac tcattgcctt
     3901 tatcttaaac tatgcagctt attttgcaga gatctttcgt ggagggatac aatcgattcc
     3961 tcaaggtcaa tatgaagcag cgcaagtttt gcaattaagt ccctttcaaa cggtgacgaa
     4021 aatcgtcatc ccacaagtga caaagattgt tttaccttct gtagggaatg aagttatcaa
     4081 cttggtcaaa gattcttcct tgatctatat attaggttta ggtgacgtaa tgcgtgctgg
     4141 gaaaatcgcg atggaacgcg acgcgacttt actgcctttg ctaggcgtgg caatcatcta
     4201 tcttacattg actggtattc taacaatcgt aatgaaacaa gttgaaggaa aattaaatta
     4261 ttaccgctaa ctgataggag gaagaaatat gattgaattg aagaaagtga acaaagcatt
     4321 tggtgaaaaa aaaataatca aagatttgaa tctaatcatt ccagatggga aaacattagc
     4381 tatcgtaggt ccttccggtg gcggtaaaac cacgctttta cgtatcttgg ctggcttaga
     4441 aagttctgac agcggagaat tttatttaga cggtgtaccg ttcaacccat tcgagcttaa
     4501 aatgaaagaa caagttgtag gagtcgtatt ccaagacttc cagctatttc cacatctgaa
     4561 tatttttgaa aacattacct tagcaccaaa aatggtattg aaacagacaa aagaagaata
     4621 caccaaaaaa gcagaagaat tagcggcttc attagggatt agtgatttat tgaatatcta
     4681 tccttatcag ctttctggcg gacaaaaaca gcgggtagcg attgccagag cattggctat
     4741 gaatccacgg gtattggctt atgatgaacc aacaagtgct ttagatcctg aattacgcca
     4801 gcaagtcgag cgtttgatcc tatcattgaa agaagatggg gtaacccaaa ttattgtcac
     4861 ccatgattta gtatttgcag aaaatgtcgg tgatcaatta ctaaaagttt ccccaattca
     4921 ttaagaaagg agaagataga gatgaaaaaa accagttttc tattcgcttt gatcgcaggt
     4981 cttcttcttt ttgcaggctg ttcgaacaaa aaaacttcag cagataattg ggcgactatc
     5041 aacgaagaga aaaaaatcgt tataggttta gacgatacat ttgttcctat gggatttaga
     5101 gataaagacg ggaagctcac aggatttgat attgatttag ccaaagcagt ctttgaacaa
     5161 tatgggatta cggtagactt tcagcccatt gactggtcaa tgaaggaatt tgaactgaac
     5221 aatggaacga tcgatttgat atggaacggc tattccaaaa cgccggcaag agaaaagaaa
     5281 gtgcaattta caaaacctta tatggaaaac gatcaagtgc tgatcacacc taaagaatca
     5341 ggaatcacaa actttggaca aatgaataat aagagattag gtgcgcaaaa tgggtcatct
     5401 ggttatgatg tatttacgaa acaaccagaa gtattaaaag agatagtcaa aaaccaagat
     5461 gctgttttgt atgatagttt taatgaagca ttgatcgatc tgaaaagcag acgggtcgat
     5521 ggtctgctga tggataaagt atacgcagac tattatttga aacaaagaaa cgaactagaa
     5581 gacttcaaca taacaaaagg ttcttatgag agtgaggatt ttgcagttgg tgcacgcaag
     5641 tcagatagta cattagtgaa aaaaatcaat gaagccctag atcaactaga gaaaacaggt
     5701 gaattccaaa aaatatccga taaatggttt ggcgaagatg ttacgccgag aaattaacaa
     5761 ataggggact gtgacaaaag acgtgtcaca gtcccttttt ccgaataaac agtgttctcc
     5821 tgccaactcc ttgtgactcg gagctgaatg gcaggctcac aacctcttgg taaacggtgt
     5881 tcaaaagcca gtttttcggt attaagccaa atttatgcaa aaatgtagaa agccattttc
     5941 acaaaatttt tcttactact cgaaactaag cgactttttc acaacctcct ttacatattt
     6001 ttattttgtt gtggaagggg tttcgtgtta ttctaaaaga ggaacgattg aaggttatag
     6061 gaaaggaaga gatgaatgga acacaaagaa cttacctcat ttccaaaaga ttttctgtgg
     6121 ggctctgctt ctgcagcgta tcaagtagaa ggagcttggc aagaagatgg gaaaggagaa
     6181 tcagtctggg atcgatttgt acggatacct ggaaagacat ttaaaggaac gaacggtgat
     6241 ttggcagtag accactatca tcgttataaa gaagatattg ctttaatgaa agaacaaggt
     6301 ctgaaagctt accgcttctc tgtagcttgg acacggattt ttcctaatgg acgaggagaa
     6361 gtcaatcaag ctgggctcgc tttttatgag agattgatcg acgaattgat tgaaaacgat
     6421 attgaaccta tgttgacttt atatcattgg gatcttccac aagcattgca agatgaatat
     6481 aatggttggg aatcacgtca gatcattgaa gatttcactc attatgcaga aacattattt
     6541 gaggcattcc gcgggaaagt ccattactgg attagtttga atgaacaaaa tatcttcact
     6601 tcattaggtt atttgttagc agcacatccg ccaggtgtga cagacccgaa acgaatgtat
     6661 gaagttaacc atattgctaa tttagcaaat gcatctgtca tcaataaatt tcacgagtta
     6721 gaaatgcctg gaaaaatcgg accaagcttt gcgtatacgc caaattatcc aattgacagt
     6781 aatcctgaaa atgttctggc tgctgaaaat gcagaagacc tgatggccaa ttattggatg
     6841 gatgtctata tgtggggaaa atatccgatt gctgccatga ggttcttaga agaaaaagga
     6901 tgggcaccaa cgattgaagc tggcgatgca gaattgctag aatctgctaa accagatttt
     6961 cttgggatca attactatca aacggcgacg aatgcattca atccattaaa cggagttggt
     7021 gctggaaaaa tgaatacgac aggaaaaaaa ggttcatcag aagaaactgg agttcctgga
     7081 atgtataaaa aagttgagaa tccatttgtc gaacgaacaa attgggactg ggagattgac
     7141 ccagaaggat taaggatcgg actgcgtcgt atcacaagcc gttaccgcat gccggtactg
     7201 attacggaaa atggcttagg agagtatgac aagttgacag aagataaaca aatccatgac
     7261 gactatcgaa tcaattactt acaaagccac gtcaaagcca tcacagaagc aatttcggat
     7321 ggagcagaag tcctaggcta ttgcacctgg tcttatacag atttgcttag ctggctgaac
     7381 ggttatcaaa agcgatatgg atttgtatat gttgatcaag acgaaacaca agaaggatct
     7441 ttggaacgat ataagaaaga cagttattac tggtaccaaa aactgattga agaaaatgga
     7501 gagaaccttt agttcacata cttaaaacaa gaaggtacgg ctggatatgg ccgtgccttt
     7561 tcttgataaa atcatttaga aattaagaaa aactgtaaaa taagctgaaa aatgaaagaa
     7621 agcgtcagtt ctttcaaaca aaactttagt tcccttactt ttttttgtat aatgaaactt
     7681 gatgaaatga gggataataa atggcacaaa agaaacggcc tactaaaaaa aggaaaaaga
     7741 cgaaaaaaac gaaaaagcaa aaacagcagc aggaacaaat gctgacgatt ggtgttgggt
     7801 ttgccttgat tttatttgct gtcttcggct ttttaaaatt aggtttttta ggaatattga
     7861 ttgcaaacgg ctttcggatc attgcaggaa atacttacca aatcctctgt cttttattag
     7921 ccgtattagg attttggatt gtcattaaga atacagagtt ttcaattggt aaaaaccgac
     7981 gctggtttgg cggcatactc ttttatttcg gtatcttatt attgttacat gcccatttat
     8041 ttggcaaact ccatactggg gaaccaaata tcatggggac gacatgggat ttgttagcca
     8101 gtgatataaa acaaagtcaa gtagacaata acgttggtgg tgggatgatt ggagcaatcc
     8161 tttatcattt tacttacttc ttgattgcac agcctggaag ttatttagca gcagtgctat
     8221 tactggcagg aggagcattc ctgttcagta atctggaagg ctatcagctg ttaaatggta
     8281 tccaatcaat tggagaacga gtacaggaat tattggaagg tgatcctgcc aagcaagctc
     8341 gaaagcaagc ggcaaaggaa gagagaatga aacagcgcgc agaagcgaaa gaagcaaggc
     8401 gcttagctgc aaaagaagct gcagaaaaag aagctgcaga atatgagaag aaaaaagcgg
     8461 tgagccagca aagggaaaat actgctgatg aatggcagga accagaaaat acagagccgg
     8521 agcagctaag ttttgttcca atcgacagtt ttcaagaaaa tatccatcct gcgaatctag
     8581 agaaaccagt accagataca ccaaaacaga ccaatacagc agaaggtttt tcagatgagt
     8641 tgccagagga tgacggtacc tcattagaat ttgagattga agcagaacag gaaaatcaag
     8701 actatgaatt accgacagtt gatttgcttg attctatacc aactgtggat caaagtgatg
     8761 agtataaaaa aattgaaaaa aatatcggcg tattagaaca aactttccaa agtttcggtg
     8821 tcgatgccaa ggtcgtcaaa gccagcttag gaccatccgt cacaaaattc gaagtccagc
     8881 cggctgtagg ggtaaaagta agtaaaattg tgaacttaac agatgatatc gcgcttgctt
     8941 tagcggcgaa agatgtccgg atggaagcac cgattccagg taaatcactg attggtattg
     9001 aagtaccaaa tggaaagatc agtatggttt cctttagaga aatcatcgaa gcacaaccaa
     9061 accacccaga taaattacta gaagtacctt taggacgtga tgtttctgga cgggtacaaa
     9121 cggctgatct ttcgaagatg cctcacttac tcgtggctgg ttcgactggt agtgggaagt
     9181 cagtagcaat taatgggatt atcacaagta tattaatgcg tgctaagccc catgaagtaa
     9241 aactgatgat gatcgatccg aaaatggttg aattgaatat gtacaacggc atacctcatc
     9301 tgttgacgcc ggtcgtgacg aaccctagaa aagcagcgca agccttacaa aaagtagtac
     9361 aagaaatgga agaacgatat gaaaaattcg cggcaaccgg agtaagaaat atttctggtt
     9421 acaatgaatt tgttcaacag aaaaacttgg aaaacggaac gaaacatcca accttaccat
     9481 tcatcgtagt gatcgtagat gaattagctg atttgatgat ggtagccagc aatgaagttg
     9541 aagatgcgat tattcgttta gcgcaaatgg ctcgggcagc ggggattcat atgatcctag
     9601 ctactcaacg tccaagtgtg gatgttatca caggaatcat caaagcaaat gtaccttcca
     9661 gaatggcatt tgcggtatca agcggtacag attctcggac gatcattgat tctaatgggg
     9721 cagaaaagct cttagggcga ggagatatgc tattcttgcc aatgggtgag aataaaccga
     9781 tccgtgtgca aggagcattc atttctgacc acgaagtaga acgggtcgtt caatttgtta
     9841 cagatcagca agaagctcat tatgaagaga aaatgatgcc gacagatgaa gttgaaacga
     9901 caggtgctcc agaacagcca caagatgagc tgtttgaaga agcaaaagca cttgtcgttg
     9961 aaatgcaaac ggcaagtatt tcccttctcc aaagaagatt tcggatcggt tacaaccgag
    10021 cagcacgttt agtagatgaa ctggaagctc atggagttgt tggcccgtca gaaggaagca
    10081 agcctcggaa agtattcatt gagcaggaag aaacatcaga aacgttgccg gacgataatg
    10141 acatgtaaaa cttgtgtgat gaagggttga aaaacgaata accaataaaa agacaaggca
    10201 tgatgatacc aaaagaaaaa atggtt
//
LOCUS       DAFEML010000076        10089 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFEML010000076
VERSION     DAFEML010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.078"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(232..1074)
                     /locus_tag="LP468_002317"
     CDS             complement(232..1074)
                     /locus_tag="LP468_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2081815.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            1399..1815
                     /locus_tag="LP468_002318"
     CDS             1399..1815
                     /locus_tag="LP468_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2081816.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIRESQQSVIDCRKLLVEQLTGGDDL"
     gene            1812..2282
                     /locus_tag="LP468_002319"
     CDS             1812..2282
                     /locus_tag="LP468_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081817.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            2296..3069
                     /locus_tag="LP468_002320"
     CDS             2296..3069
                     /locus_tag="LP468_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081818.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            3083..3895
                     /locus_tag="LP468_002321"
     CDS             3083..3895
                     /locus_tag="LP468_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081819.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3949..4914
                     /locus_tag="LP468_002322"
     CDS             3949..4914
                     /locus_tag="LP468_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2081820.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAANLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            5030..7753
                     /locus_tag="LP468_002323"
     CDS             5030..7753
                     /locus_tag="LP468_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2081821.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7766..8398
                     /locus_tag="LP468_002324"
     CDS             7766..8398
                     /locus_tag="LP468_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2081822.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9297..>10089
                     /locus_tag="LP468_002325"
     CDS             9297..>10089
                     /locus_tag="LP468_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081823.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3379 a         1554 c         1964 g         3192 t
ORIGIN      
        1 cgtaagaaac cgttaggttt agctaagtgg tgagtagttc actaaggaag taaacccaca
       61 cagaaatata ggtgattttc cttgaatgac caagatattg aaagttagtg aaaaaacaca
      121 aaaaggtagc cctattcaca gaaggtctgc cttttgtgtt atcgccagca aacattagag
      181 gggatatttc atatagcttt tgtcctctcg acagtcctat cagtttctct tttaacttat
      241 ctctaagtgc tgtccagttt taatagcttc tagcttgttt cctaactgtg tttttaatat
      301 gttgaaggct tttgaacctg tgcagtggca agtaaggatt ttttctactc gtgagtcatt
      361 caatttattt ccaattttca ttacctcttg ctcaggtaga cctaaattat ttatataagg
      421 tatgccaatc atatggaagc caccgattag gtattttatg ggtttagtcg gaaatgtttc
      481 aagagcaatt tccatcatat cgataatgcc atgatgacta cagccagtaa atacaatcag
      541 accgtcttct tgctcaatta cgaccaataa ttcatctgaa aaatcatcat aaacaaattt
      601 atcatccatc tttttgtata aattcttggt ggtcgagttt gctttgccta gggggatgat
      661 atggaagctc ggagcaagtt ctgttttcgt ttttattgta tgtaaattct catgcatttt
      721 aaggatttca tttttaggaa taccaacata cagaaacgtg gttaaaatct ttaaataatg
      781 gggtaaagtt acaccttcag ctgtataaat aggggcgttt cctgatttta aatatcttaa
      841 cccgccggtg tggtcagaat gaccgtgtga aataatcact gcctccagat cattcaaagt
      901 ttcccccatt ttagtcgcat tatagactaa ttttttatta gcgccagcat cgaagagata
      961 tttcttccct gagtagttaa ttaagagaga taacccatgt ccacttttaa agttcaaatt
     1021 tattcttgag ttttcaaata aaaccttgat ttccactata acatctcctt tcacatgaac
     1081 gtgtattcat atattgtagc acattaagtt ctattttttg ttgtaattac cgaaaaaaat
     1141 attaatggac gctttttacg ctttatttcg tatgtggaag aaaatttctt aggatgtggc
     1201 gggggattgg ggcaaagcta aattccaatt acagtgatca tttaattaga cacctttaaa
     1261 tacccacact ttcatcaaca ctataattta gggaaagaaa agtgttggca tgatatagaa
     1321 aaacctttaa ttgacagcgt ttcctaaaat tggcacgcat cttgcttata gaaaagcgta
     1381 aggataggag gaatgaaaat ggcaactata attcttgcca gccatgggga atttgctcaa
     1441 ggattaaagc aaacagcgac aatgattatt ggagatagtg taccaattca tgccttgtca
     1501 gcatttagag atgaagatga atctattttg gtacaaataa aaaaactttt agccacaata
     1561 gatatagaag aaacctacat tttaactgat attctaggtg gtagtgtgaa taatgatatg
     1621 ctcactatta ttaaagagta tgagggattg caattaatta ctggaatgaa cttaccttta
     1681 gttatttcta ttgcaaccta taatggaaaa attggggaaa gtgagctaga aaagcttatt
     1741 agagagagtc aacaatcagt gattgattgt agaaaattat tagtagaaca acttactgga
     1801 ggagatgacc tatgattaaa ttagtacgta ttgaccatcg tttgttgcac ggacaggtag
     1861 tattttcttg gagtaaatca ttaaatatca atcgtattat tattgccaat aaagaggcag
     1921 cgaatgatga attcaaaaaa atgtctttga atttatctaa accgactggc attaaattaa
     1981 caattttttc agttgaacag ttactagaaa aaatgcctaa aatcgaaaca cttaacgaaa
     2041 atatcatgct tatttttggt aatacaaaag aaattcgtca attttgtgaa gcctatccta
     2101 aagtacaaga aatcaactat ggagggataa tcaaaaaaga aggttccaag caatttagta
     2161 atgccatttt cttgaatgaa tctgagcaag aagatgccaa aaaattaaaa gctcttggca
     2221 ttaaacaatt tattcaacag gtaccaactt ctaaaaaaga agatttgaat acaatgttat
     2281 aaaggaggaa tgaaaatgct cgttcagtca attggtttag ggttaatcgg tgttttttgt
     2341 attttagact caaggctttt aggaagaatg aattttgaac gaccgttgat tgtcagtacg
     2401 cttgttggtt tggtacttgg agacatggaa aaaggattaa ttgttggagc ctctttggaa
     2461 ttgatgtcct taggattagt aaatatcgga gctgctgcac cacctgatat gaatatggca
     2521 tcaattattg ctacagcctt tgccatttta tcaaatgcga acgcagaagc agcattaacg
     2581 attgccattc caatttcagt gttaggtcaa atactaggta tcttaatgcg gacgattttg
     2641 tcaaatttga ctcacgttgc ggatcgcttt atcgaacaag ggaaatttag ccaagcaagg
     2701 agaattcata tactttatgg ctcgggatta tatgctctca tgtattttat tcctattttt
     2761 ctagcaattt attttggaac gaatcttgtt tctcagattg ttgatgcgat tcctgagtgg
     2821 ctaacaaatg gcttaacggt tgcaagtaaa attttaccag catatgggtt tgcgttgtta
     2881 ttacaaacga tgttaacgaa aaaaatggtg ccatttttat tacttggatt tttaattact
     2941 gcttattctg gattgggaat cattggtatt gcagccttcg catgtattgt tgcgtttgtc
     3001 atggttcaag ttcaaggtaa aaactcaaat ggtaaccaaa atgagccaga tccattagat
     3061 gacttataag gaggtagatt aagtgaaaga gaaagatcaa aatgcatgga aatatcggca
     3121 gttcttatgg cgttcatggg caattcaagc ctcatggaac tatgaacgac aaatgaacat
     3181 gggttttatg tacggaattg caccaattct agataacatt tacaagaatc cagaagatga
     3241 agcaatgaag aaagaagctt acgagcggca tatgatgtac tacaactgta cccctcaaac
     3301 aagtgcattt gtgttagggt taactgcttc tatggaggag caatactacg aagaccaaga
     3361 aaactttaat ccggaatcaa tcagtgcagt gaagacttct ctgatgggac cgctatctgg
     3421 tgttggtgat tctttctttc aaggaacgat tcgggtatta gcctttggac taggaattaa
     3481 tttagcccaa caaggtagta ttttaggtcc aattctagca atgttaattt cctttgtacc
     3541 ttccttttta gttacttact atggtgggaa aattggctat aacatgggga ataaatactt
     3601 gtctaaactg tatcaagaag gtttgatgga taaagtaatg tatgtttgct ccattgtggg
     3661 gttgatggtc attggttcga tgattgccag catgatcggg attacaacac caattcaaat
     3721 gggtaaagct tttgtcttac aagatgtatt agatagtatt atgccacaat ttttaccatt
     3781 aggattaacc ttcttcatgt actggttatt gcagaaaaag gtcaaaacag gatggatgtt
     3841 ggcaatctgt ttagtcggag gaattatttt tagtttgtta ggtatcttac aataagggaa
     3901 taaccaataa atttggttga ataatataaa taaggaggaa ttcaattgat gaattcaaaa
     3961 gaaattgtta aagaaatcgt agcgaaaaaa gaggtaaaat caatcgtatt tgttggctgt
     4021 ggcgcttcaa aagcggacct ttatcctgca aagtattttc tagaccaaaa tgcgaagcag
     4081 ttacggatta gtcattacac agccagcgaa tttaactatg caacaccagc atctgtagat
     4141 gagtcaactg tcgttatttc agcttcttta ggaggtacga ctccagaaac agttgaagct
     4201 aacgcagtag ctaaagaaaa aggtgctaca gttattagtc taacacgaag cattgactca
     4261 ccgttaacaa aagatgcaga ttatgtaatt tatcatcgat ttgcagagaa ctatgctgct
     4321 aacttagaaa aaacaggcta ctgtttagaa ttggcagtag aacttttaca tcaagtagaa
     4381 ggttatgacc attatgaagc aatgcaagaa ggatttgcta ctatctatga tcttgcccaa
     4441 aaaagtgcag aatcagctcg taaagatgcg aagaaatttg ctgaacgctt taaagatgaa
     4501 aaagttattt atgtaatgag tagtggtgct acacatgaag tagcatactc aacatcaatt
     4561 tgcttgatga tggaaatgca atggattaat tctggtacct tccattcagg agaatttttc
     4621 cacggaccat tcgaaattgt ggataaagac gtaccgttta tattattaat gaatgatgga
     4681 aaaactagaa atatagatgc tcgagcatta actttccttg aacgctttga tacgaaaaca
     4741 gaagttgtag atgccttgga ttatggcttg tcttcacata ttgctaaaga agtcttagac
     4801 tactttaacc cattcgtgat tactgcagta tttagagttt atgcagaaga attgtcagaa
     4861 gcaagagaac atccattaac taagagacgt tatatgtgga aactaactta ttaaaaaata
     4921 gatcaaacta aataaggtgg cttgagaaat taagccacct tattttcttc aatgtgattt
     4981 tatacatatg gtaaaataac tagtacatat tgtgaaagca ggtggcaaga tgcagcgatt
     5041 aaatgactat ctttatcaac taacattgct tttgaaatct acgccttcag ataattattc
     5101 agctcgcagt atttcgcaag ctttacagtt gaatagaagt acaatcagta gctacttaaa
     5161 tgaaggtgtt cgtgaagggc ttttcataaa agtaaaaagt tacccggttt tatttttaca
     5221 tagaacagct cttgaagaac tacatatcac actgaataac tccgaaatag aatcaattga
     5281 aagcttgtta acaatttctc aaaaacccgc attagatcaa gtaattggct ctaaaggaag
     5341 tttgaaagaa gcaattgatc aaattaaaac ggcagtctta tatcctggaa aagggttgcc
     5401 tttattattg atcggcgcta gtggatcagg gaaaaccttt ctagcgaata aaatatatga
     5461 atatgcagta gaagaaaagg tcattcacac atcggcacct ttcatagatt ataattgtgc
     5521 acaatatgtg agcaatccag agttactatc ctctgcttta tttggctaca cgaaaggagc
     5581 atttaccgga gcaagccagg agcatactgg tttgctagaa aaagccgatg gaggagtatt
     5641 gtttttagat gaagtgcatc gcttatctga agaagggcaa gagaaattat ttacatttat
     5701 ggatacgggt gaattctctc ctatggggga taatagtatt cggaaaaaag ccgatgttcg
     5761 attagtcttt gcaacaacag aaaatatata tacgactttc ttaccaactt ttcttaggag
     5821 attgccagtt attgttaatc tacctagatt tcaacaacgt ccgtcgtttg aacgtctgtc
     5881 attgattgat gaattttttg tttctgagag taaaatttta gctaaggaac tatctgtttc
     5941 tgatgcattg attcatttct taatgaatag tgattttgaa ggtaacgtgg ggaatattaa
     6001 aaatattatc aagtatgctt gcggaaacgc atatatccac cagaagagtc agcaaacaat
     6061 tcaagttaaa ttattggata tgcctttaga gtacagttat aaattcaagg agcaactaaa
     6121 taaacccaga aagaaaagag cagatcgaat ctactatcca gaagaaacac gacaagtgca
     6181 actagaaaga aacaatcagc tttttgttca attttttgac caattactta ctggattctc
     6241 tgaagtgatt gaaaataaca aggatattaa actattttta gaagaaatgg ttaccaaggt
     6301 aacacaagta atggatacgc ttatttttca agaggattac gaaaaagagc agtctttata
     6361 cgccattcta aactatcata ttcgtcaaag tattgatttt atgcgagaaa gctacgggtt
     6421 tgaacaagat ggtaaccggg tagtcgcttt ggccaactat ctatatgtca aggataatca
     6481 agtgattttt gaaaatagtc ttcaagaaaa gaaaaccaaa gatcagctta acgaattttt
     6541 tgctaatgtt cttgaaaccc cttattggta tgcaaaaaaa atcttaagcc ttttatctga
     6601 gtgtttagat caacctgtgt atgaagagga cattttcttt attacgctat atttttatag
     6661 tttgaatgtc acgaatgtta aaacaggtat taagagtatt gtgctagctc atggttattc
     6721 tacagctagt agtatggcga atgttgccaa ccgtatgctg aataagaacg tttttcaagc
     6781 ttatgatatg cctttagata ttacattaga gaaaattgaa gcaaaattga ttcaattcct
     6841 tggagattat cgaacagatt caggcttgat tttattggta gatatgggtt cactaaacca
     6901 actaggcggt ttattagtga atcatctaaa tggaccactg ttaatcattg atcatatcaa
     6961 tacaccgtta ttattggaag tcggccaaca agtattaaac aataaaagta tcaccgaaat
     7021 aggagcagaa attgaaacaa gtcttacttt caaaaagcag ttactacttc ccaagaaaaa
     7081 gaaaaagaaa gccatcatta cttgttgtta tacagggatt ggtagtgcga cccagattca
     7141 ggagatttta acgaaatgct tgaaagatgc agttagagaa ttagtaatta ttccgtatga
     7201 ttacaaaaag ctgttagaaa acaagaattt tgagactcct tttcaattat acgatgtcat
     7261 catgattgta ggtacagaag atcccaaaat taatcagatt ccatatattg gattagatcg
     7321 cctgattaat ggggaagcaa ttggcgaatt tgttcattac ttggaaaaag agctgactat
     7381 tgaagtgaac gatttacaaa aagaattaat tttcaatttt tcaattagta aaattgtcga
     7441 aaatttaacc attttggatc cagataaggt gctatctttt gtacaaaaag caattaaaga
     7501 attatcgaag ttattaaatt ttgatttttc taataatcag ctgtttttgt tgtaccttca
     7561 ctgtagttgt atgattgaac gaattgtacg taaagaaagt gtggatgagc aagaggacat
     7621 tgaagaatat atgcaagcaa atggagaaat aatggataaa attcatagcg ctttttttga
     7681 gattgaaagg gaatacacaa ttgaaatacc agatttagag ttgcgattat tgagcgatat
     7741 tgttcaagga taggagtgaa ttcgaatgac aatgggagta atttttgata tggatggggt
     7801 actcatagac agcgagacat tttattttga gagaagaatg aacttctttc aagaactgga
     7861 gatagatcca ggatcaaacc agattgatga ttatgtgggg aaaacagaag ctgcaatatg
     7921 ggaaacatta gttcctgagg acaaatcatt aagagaggaa ctttatccga aatatgtaga
     7981 ttatcgaaaa acgcatccaa ttgatttcgc taaagattta cgaaaagaag tgaaaccgtt
     8041 acttgacttc ctcaagaagc gggatatacc attggcactg gcatcttctt ctccagttgt
     8101 tgagatagag agtatgctca ttcaatgtga acttactgaa tatttttcct ttgttataag
     8161 tggtgagtca ttaaaacaaa gcaaaccaca tcccgaaata tatttaaaag cgaaacagca
     8221 attagactgt gacttcttta ttgcagtaga ggattcaacg attggtatta aatcagcaaa
     8281 ggcagcaaat atctatacgg tggcactaaa acaaccaatg caaatcgatc agagtgaagc
     8341 agacatacaa attgaaagtc tacaagaact ggaacaaatt gttttagaaa aaggttagtg
     8401 aattaatgga aataaggcta tatatctgtg ctagctattt tgactaacca aaaaaacttg
     8461 ctataattca ggtgtagtaa aaggtgctgg taacaccttt tacgaaaatg cttcggcagt
     8521 gataatggga ttggcttttt aagtttttta ttttgctcgc aatccctaag gtcatgtgaa
     8581 tgatcctagg gattgctaga atattttgca acattctatc tatttcagaa cgtaaccttc
     8641 cccagttcat tgggattcat tagcatacaa ccaacatttc aaaaagaaat tgcactacac
     8701 cattattagc tattttgact aaccccaaaa aacttgctat aattcaggtg taggtaaaag
     8761 gtgctggtat caccttttac gaaactgctt cggcagtggt aatgagtgtg gcttaaagga
     8821 ctagtccttt aagcttttta ctttgttcgc aatctctaag atcaagttaa tgatcgataa
     8881 gattgctaga atattttgca acattctatt tcagaacgta acctttccca ttccactgtg
     8941 attcattggc aaccctcctc acaaccaacg tttcaaaaga aattgtaaag ttgttggggt
     9001 accacgaccg aacaatacta cacctgaatg atagtaagtt gtctcattaa gtatagcata
     9061 tcctcttttt gggtaaatag aaatcggtta cattttttat ccaagaccaa gttttttcat
     9121 ttggtcttat ttgctatacc caaacaattc cgcagtatag tcgacggtat tgattttatc
     9181 aggtgagtaa tagaaacttg ttttccttcc ccaaaacatt acctataaag gagaaaaaat
     9241 ggtatcgtaa ttatataggt ataggatgaa atttttttct aagaggaggg ttgttgatga
     9301 aaaatttaca gttaaaattt attgttgatc catcgattgt acgctggttt cggattatca
     9361 atcaatttga gcgcaatcaa cttgccacaa aaggagaatt agcaaagagt aatcatgtat
     9421 ctgaacgaac cattcaaaca gatgtcaata aaatgaagga ctacttttct gaaagtgttc
     9481 aatttgtttc aacgaaaagt gggtattctt ttcagaagga aagaccggtt ctttttctca
     9541 agcagaagga gcaactactg gagaacgaaa ttttatttga gttgttaggg aatgtctttt
     9601 atggcgaatt ggaagatatg acggagctaa ttgatcgttt tcatttatct gaagcgactt
     9661 ttcgtcggta tttgaagcag attcaaccag ttttggaaga atacggctta gaattgagtc
     9721 tttatcctct tgatttaaaa ggagaagagg caaatattcg caagtttttt aaagacttct
     9781 attatgaggg ggagatgacg ccccatactc ttgttccacc aagggatctt catgaacttg
     9841 tgcaagctac attctatgat aaatttgagt atttctcgat tggaacaggg acttctcctg
     9901 ctgaatttta ttatagtttg tatattgcga ttgagcgtgt gagacaagga aaaacgatag
     9961 ccattcctca aggtctgatt gagcgagtaa ttgctagtga gaattttcgc ttaatgtatt
    10021 ccttgaaaga agcgattcaa acaaattatc aagttgcttt atcagaagag gagttttgtt
    10081 ggttgtatt
//
LOCUS       DAFEML010000077         9977 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFEML010000077
VERSION     DAFEML010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.079"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(25..162)
                     /locus_tag="LP468_002326"
     CDS             complement(25..162)
                     /locus_tag="LP468_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL2081824.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            complement(159..1343)
                     /locus_tag="LP468_002327"
     CDS             complement(159..1343)
                     /locus_tag="LP468_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL2081825.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(1599..1853)
                     /locus_tag="LP468_002328"
     CDS             complement(1599..1853)
                     /locus_tag="LP468_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081826.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(1878..3020)
                     /locus_tag="LP468_002329"
     CDS             complement(1878..3020)
                     /locus_tag="LP468_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL2081827.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(3080..4432)
                     /locus_tag="LP468_002330"
     CDS             complement(3080..4432)
                     /locus_tag="LP468_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2081828.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(4503..4847)
                     /locus_tag="LP468_002331"
     CDS             complement(4503..4847)
                     /locus_tag="LP468_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL2081829.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(4857..5231)
                     /locus_tag="LP468_002332"
     CDS             complement(4857..5231)
                     /locus_tag="LP468_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2081830.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(5244..5558)
                     /locus_tag="LP468_002333"
     CDS             complement(5244..5558)
                     /locus_tag="LP468_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2081831.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(5672..8899)
                     /gene="fss3"
                     /locus_tag="LP468_002334"
     CDS             complement(5672..8899)
                     /gene="fss3"
                     /locus_tag="LP468_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL2081832.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(8978..9640)
                     /locus_tag="LP468_002335"
     CDS             complement(8978..9640)
                     /locus_tag="LP468_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081833.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
BASE COUNT         2690 a         2253 c         1705 g         3329 t
ORIGIN      
        1 aaattttgac cgaaattcat ttcatcactt tcctttcttt tccattgctc ggtccgccgc
       61 tgcacttgca tgcatcaagc acatcacagt aacaccaagc atactgccac caaacaccaa
      121 taaaatatct ttcacaattt ccatcacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatctttttg tgccggtctg atagtcgagt attatttacc
      241 atatcctgaa tgtacgttgt ctgattcaac cgatccaact ccttggccat cttccacgta
      301 ggggcgactt gtcgtccaag ccagttcaac gttcgttcaa tggtataagg cttcggttca
      361 gaagttaatt gaatttcctt ctgattccgt ccaatgaagc gcccccattg ttcattcaag
      421 ggccagttag ttcgcctttt gccttccacc ttatccgcaa atcgcaagta ccggttaata
      481 atggaaaatg tggtactttc aatactgcga ccttttaaca aatcttgaat tgcatgataa
      541 gctcgatcat ttttcagtcg gatttcaaaa cgatttttcg tttcggtctg gtctaaagga
      601 atccctaact tgatatattg ctcatagtct ttttcgtaca aacagaaata gacctcactc
      661 ttaagactgc caatatacaa agtattgccc ataccatctt tatcatcagg tttcaacagt
      721 tccccggaac gatagctttt gaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta aatcaggaat atctaacagg ccaactcgat cattgattgc caggtctaag
      841 cgtttcatca cgccaccggc ttttagacaa tcttcgaaaa agtcatacca gctacgcttt
      901 tgggcgagta aaaaagtttc aaactgccga caaccacgac cctttaattc taaaaggacg
      961 cctttatctt cttcatgtga caacatcacc acaatatctc ccataacata ttgttcttga
     1021 taggagtaaa aggcgtaatc ttcgtggagc atataatcaa atttcaaatg gagaatctct
     1081 tgaatgattt tcctcgcatc cgttgtggga aagcgaatcc ttacatagtc aaacagtaac
     1141 gttaaaggta actcgggatt gaaactttcc agttggtcaa aaattttcct catggttttt
     1201 gtcgatgcgg ttacgccacc attttctatc tgatttaagt acgggcgact aagtccacaa
     1261 gtcgtagcta atttattttg tgaaacgcca tattcattac gccggtcttt taatagccga
     1321 taatctaaat tcctttgtgc caagttctca cctccaaatt taaggtgtta actttttcaa
     1381 atcagttaac atctacacaa attgcttatt atccttgata ggacagccat tccttatcgt
     1441 tgcttgctta ttttttgtgt ttttgtaccc ccctgttaga tacggggggt gagacatcat
     1501 ggccggctaa cgccgtccat aaacaggcac agcaccacgg aggatttctg cttcgcaaat
     1561 cccccgcggt cagtgcctat cagtggttta tttggccgtt actccgcggt aataccctca
     1621 atttccaact ctgcttttat ctcaaacaag tattggcgga tatcaggttc tttagcaaag
     1681 tccgcaattc gttccaattc actgatgact tgattcagct ccattcgagc atccgtttcc
     1741 tcatcaatta catacggatc atcagggact ttcaccccgt ttttgcgaat atcaaaattg
     1801 agccggtaca gttcttcttc caattccgga tctgactgaa tcttgccaat cacccagtag
     1861 attccccaat caactcatca taaatcatct gtttttacct cctttaatct tctagcaata
     1921 tcaaaaatga ccggaactgt tacagaattt ccagcctgct tatacaactg actatctgaa
     1981 ttgacttgag aagctcgatc aaaagcccag tccggaaagc cctgaagccg ccagcactcc
     2041 ctaggtgtta actttcgaat ttgatactga tccgtgacga ctgcttgttg gtctcctgtt
     2101 aataaggtat gcacactttg ttttcccaga cggcctcgac gacttgtgga attaggaaaa
     2161 gccaggttca cactgttccc tggcttcacc tcttgatatt ctgtttcgtt tttccgaagc
     2221 atgatcttcg ttccgccttg tttcgttgac aaagtaggcg ctgttccagt tatctcataa
     2281 acccgattgc cttgttcaaa atttcccagt aacatacccg ctacagaaat tccatcatct
     2341 accggcaatg cgattttgat tccttcatca ccggtcaagg taggcgctac gtcatctgac
     2401 ccatagactt gtccccccat tcctcgattg gaagggttga tatttaataa gtttctgatg
     2461 ttttgatcag atgttggaga cgatccaatg ataggaaata cttgttcggt acatgcgtct
     2521 cgagaatgtc cgataaggaa gatccgctca cggttttggg gaacgtaggc ctttgagtta
     2581 agcacttgcc attccacatc ataccccaat ccatccagcg ttcggaggat cgtctcgaac
     2641 gtagcccctc cttcgtgatt gagtaatccc cggacgttct caaggaataa aaacttaggt
     2701 tggagaatag cggcgaaccg agcgatttca aagaataaag tacctcgagt atcggaaaat
     2761 ccttgccgct ttcccgcaat tgaaaaagct tggcacggaa atccaccgca aaggatatcc
     2821 actggtccga gagattgaat aaactcgtct gatacacttg tgatgtcatg catttccacc
     2881 tccttacttg tatcatggat tgccttataa ctctggcgag caaaatcatc aatttcacaa
     2941 aagccgatac actggtgacc cgcttgttcc atacctaagc aaaagccacc aatcccagcg
     3001 aataaatcta aaaatgtcat aaatcacctc gtaaaaaaag cccaggattc ttgacactcc
     3061 taggctacat actattattt tatccttccg tattaacgtt taatccacca atgtcgctaa
     3121 tttcccttaa gaaatcatat ccttttggta caagtggcgt ataaaactca ctaatcacac
     3181 tccctcccgt atctacatag cctcgacctt tgatacgctt cataaagaat tttttatcaa
     3241 cctcgccaaa catcatggaa tatcccagtt cactcatacg acccaaagcc acccggaaat
     3301 taaattgatc gcgaatcccg tctcctaaat atttcgcatc cggtctttga caagctagaa
     3361 tcagaaagaa accagattga cgacctaaca tcacgatttg tttgagctta ttcaaaatca
     3421 ccgcactttc cttcgtcgtt aacatttcca tataaaccac gtattcatca aagattaaaa
     3481 agtttggtgg aagtccaaga aacgcataat tctctcctgt tttgtagttg ggcatttctt
     3541 tcattgcctt gctacgagtc atcatgcgct catagaaatc ttccacacaa gcagaaattt
     3601 cctccttttg ggaatagaca tgaggcatta ccgtacctaa atcggctaag tccgcatttt
     3661 tgggatcaag aacaaaaagc tcggcatcag attttaataa agcctcgatg atagtgagta
     3721 aaaagtaagt cttcccacca cctgtgccgc cagcgattaa catatgaggt aaagaatcat
     3781 aagcccatac ttgatttttc atcaatcgca aagccccact ttctgccact acttcgtcta
     3841 tcccaattcg attggcaatt atatcataca gtaaagtgta ctccacatag gagtctttga
     3901 gttccttttc tactagttca caatatagac cactttctaa cttcttttcc agctttaaaa
     3961 gctgatcttg atattttccc agtgaaattt gaacgcgaat agaaagtaaa ccatccttca
     4021 tacggtaata gattttgggg aagtaactga ttgtctcttt ggttcgacta ctattgaggt
     4081 ctttgaaaaa tccttcactc tgagtttgtt ttacttcgta ccaatgattt tctagaatca
     4141 tccgggctag cttttgtcga tgccacaaac tgcgccaatg atcctgaaaa aagtgtatat
     4201 aaagcaacat cgtgcttcct gaaagaacga gacttcctag caaatagatt aaatctttta
     4261 tagaacgaac gatttctata gtagaaagtg atagcttaga aatatcaaat tgtctaagct
     4321 cttgaaaata aaagacgctc atccaaccga tgaacagagc gagtagccag ccaagaacaa
     4381 agtgataaac caagtgctga tctcctgccc gtatacgatg ccctttgtac atttttatgg
     4441 tttccacctc caatcgaaaa aagcttcata ggatttcatt gatccaattt caagcagtta
     4501 tgctagtcat ttactgctat agggagttgt ttcgtttcca ctagttgctt taaaaaaact
     4561 tcaatggcat ccggcatttc cacaccaatt tcttccaata cggtttcggc ttctcgacat
     4621 agactttcat ttacttcgat aaccataaag aaggactctt cttcccctaa ccaattcagt
     4681 acatcaaaat cttcttcggc atcgttacct acttccagta acccttgatg cataatcaga
     4741 aacatttttt catcataggt taatgcttta gtgagttgtt cctccgttag ctcacctttt
     4801 ccatattgat cgagacaatc taaaatatgt tcaacattaa tttccatacg cttcacctat
     4861 ttctttcctt cattttggtt tgtagaattt ccctgatctg gttgtcgttt caagactaaa
     4921 tcatcggcct taatgaacca attgacagta gttccttctc ggaaaacata attggcgacc
     4981 gtatccatga ttggattgac caactctacc tctgcgtcat aggcaaactc gcgtaagggt
     5041 acatttgctg ggatactaac ttggatcatt cgaccttgcg cagaggattt caaattataa
     5101 gtccgttctt ttacctcgtt actaaccgtt ccatcctcat tttgcttccg tacttctcgg
     5161 cgtaatgcgg aaaatcgtaa tttcccaaac gttagtcctg aatctacaac aataccttct
     5221 gttaatctca tcttcttttc ctcctatgct ttcactaaat catcgacata caacacgtag
     5281 tcggtaaacc cacgattctc aatctcatag cctttggcaa ccaaatgggg attcacggct
     5341 tttagtggtt gatcttgatc aaaatccttt tcgccggctt ccgcagctac caccacttca
     5401 atatcatcgg ctcgttgctt actggaatac aaatgataac tacgaccaat tactgtagta
     5461 ttccgcccat atccttcagt taaaacttcg ccttcgccgg cataccttat ctttccaaag
     5521 gtttcggcca tatctggcac aacaaatttc aattccatct tcttttcctc ttttcatttt
     5581 tagttttgga tacaaaaata gcgcgaccac tttttttagg aggcggtcgc gcacgttggt
     5641 ttttcctatt tagttgtttc atcacatcac cttagtttcg gcgattccag aaataatacc
     5701 cagcagtcgc aaagatcaag gtaaacccaa taaacagcag aacattagaa tttttctccc
     5761 ctgtttgtgg gaatgtcttt actgtaggac tagattcttg agagtcactt ggaacagttg
     5821 gtatttccgg ttgttctggt gcacttggtg ttgtcggaac ttttttaggt gttaaagttt
     5881 gagttttttc ttttagatcc tcattgtgtt tcccattgat gtttccgtct ttgccatagt
     5941 taatttcttt gaaggtaaaa cttgtacctt ctggatattt acttgtgtcc actttttccg
     6001 caagtacggt tttagtgaat tctttgtcat tcacttcata atcaattttg ccagatttcc
     6061 aaatttcttt ggtcgtatta tccggaagta atgcatacag aattgtttca aaagcttctt
     6121 ttgagccatc cagtacatca tgggtaatcg acacatcatc gaacatatcc accacatccc
     6181 catgagtaaa ggtttgcgaa ccatcttcta ggtgggcttt tgtttggatg gaaacatggc
     6241 gttccaccgt acaattgaca gtttgggctt gattgttcaa gctagcatct ttcgctactg
     6301 gatcatcacc tgcttcatag ggtttcttgt tttcatacac atagttgaat aagacgatgg
     6361 ttttatccaa aacttgttct gcggttaatt tatgcaaaat tttccaagtt cctgttttct
     6421 ctttattcgc caacgttgcg gttgtttcgg caattaccac tggtttggct ttttcatctt
     6481 tttcttgggc agcttttgtc gcttccacat caatggcttg cgctaccaca taccagtctt
     6541 ctttgatttc atgcaagtta tagctcaatt tatcaactag ctcggtagaa tcaaggtctg
     6601 tcaattcttt gcctccgtct ttccaagtcc caagagaagt taagctatct tcttcttcag
     6661 gtaaatcata gagcatcaaa cgattcaagc taacagaaaa tgctttattc gtcagtttct
     6721 cgtaaggaac ggtcaccgtt ttaattggtt gtttttgtcc tttttcggta atcgtaaaaa
     6781 tgtattcact cttagtgtaa tccgctttat tttctttaaa agtagaacgg atttctaatg
     6841 gcgtaatttt ttgaaatcct tctggagcct ctacttcttc aagtaaataa tccccataag
     6901 gaagattttc aaacttgcca tagccatcaa aacctagttg ctcgttataa gctgtaattg
     6961 cttcatcttc ggcacctgta atctcactgg ttccttccaa tggcgatact ttaaaggtca
     7021 gatcattgaa gccagtttcg gcagtcccag cagctgatcc agcaaattta aagaaatcaa
     7081 agccaaagcg aatgacttgt tcttttgccg taacatctcg ggtaatcacg gcattttttt
     7141 cgttatcatc cacctttttg atggaaacag ggtactttgt ttcatccaag gtatatcctt
     7201 caggtgcttt ggtttcttgc cagtaatact cattaatcgc taagtgttta acagcaactt
     7261 gattcttttc atctaaagtc aaagtcaccg tttcatcaga agctttcgtt cccttcacta
     7321 actctggttt aaaagcctca ctccatttga ccgcttgacc atcttttgca gtaaagagag
     7381 tatattcagc tcctttaaac tcagctttac cttgagtttc attaccggta tctttgtctt
     7441 cttttgtcaa agtggtttca ccagtgattt cttggttttg cccttttacg ttactggtaa
     7501 caagagccac ggtttgattg acatagttca attcgacttt tactggttta aaggtattca
     7561 caaagccatt actagctttg gtttcggtca cataataggt tcccaattcc aacgcattgg
     7621 caatctcttt tggtgtttcc gcatgacctt tttcatccgt ggtcatttct tggacaattt
     7681 caccggttgg actgtctttg cgaatggcaa acgtatttcc ggctaatgag tatttgtcgt
     7741 tccaaagatc agttcctgtt tccaccccca ttttattcaa aatgatttga cctttttcgc
     7801 gagtattttt tgaagtcaca gaaatagtct caccagattt aatggttgcg gtgattggtg
     7861 tagtgtcaat cgtataagga gctggcactg atttttcagt aatggttact ttcgcgccat
     7921 gaggaatctc atccaatgtc gcaatgcctt ctttatcggt ggtcacgtct tttgcaggta
     7981 atgtttttcc aaagtctaaa tggaaaacgg ttcccggtac aacatttcct gtttctttat
     8041 cgactttttt aatcttcaaa gaaccctcag tttccacatc aattttgatt gtgtaggtat
     8101 tgggcttatc aattgccccc gccatcaaag tttgttgacc agccatttta taagctaccg
     8161 gtgttcctgt attagctgac ttctttaggg ttaattcacc actctctttt gaattggcat
     8221 ttggagtaat cactagttga ttgccgttca cacgataatc aatatttgcg atattctcga
     8281 caacttcatc aaactccgat aaattcaagc cgttcgtatc tgtcacagta gtcgattgac
     8341 ctaacacggt tttcactgtg gagttatgga agcttggttt cttttgataa tccgcaatgg
     8401 cttgattgat ttttgactca atggctgcga tatttactgc actaccatca gaacgtttaa
     8461 ttgagtgaag cgtgtagcca ttaacttctt gccaaatcat cttctgggcc acaatatgtg
     8521 tatccacatc cgtaccagct tccttccata aaacggaaac taatttcgct ttctccgaca
     8581 tatcaggcaa tggatttttc tcataaccag gagtgaactc attgtaaatc ggcacccctg
     8641 gctcaataca gaaaatatct tgcttcacac cattgtaaac tgcatagtgc ggaacggtaa
     8701 cttctgacat gggacgacca tcgctaaatg taccttcgac agcatactgg tgagccaaat
     8761 ccaattccac agttaccgtt tgtggatgag taatttcatc agcaaaggca atcgttgggc
     8821 caagcgatcc accaattgtt tggcataata gactcagtgt tgcgagcaaa cgccaattct
     8881 taaatcttgg ctttttcata aaataaatct cctttcgttt ttgggtaata aaaaagacgt
     8941 ccaaatttta attttgaacg tctgatttag agtgatacta tttagttttc tttgtcttgg
     9001 ataggttgtt tctctgctta taaattttga ttcttcgata atcaaatcca atctctgcca
     9061 tcaattcctc ccaatttttg ttcgttcttt tcataattgt atcaactgat ggtagttttg
     9121 gggattgaac tagttttcga aactttgtca ttgataaatc atcctgtagt tttaatcgga
     9181 ttatttcatt ttttagttct aacagcagtt cgaaatcagt aaatcgagat ccatcatttt
     9241 tttctttaaa aagtggacgt atatctccta acatcttttt aatggtacta agtgaaggaa
     9301 tattcttccc tactgatttt tgttcgtaca ttcgttgaga ggttatcttc tcgcacttaa
     9361 taaaggcttc tactatttcc aataattctt gttctgacat tctagcccat tttccatacc
     9421 cagtattttc tcgtcctata ctaatcaata aattctccca tgatccatat tttttgttaa
     9481 tgaaccacat acttggtgca gaatttggat tttctgatag ctttttctgg tattgacggc
     9541 tagatgtaat tccgtgtttt tcgatgaatt cattaattgt taaaatcagt tttaactcac
     9601 tttgattttt ccaaatgata cgtccatcat tttgcttcac gataaaaact cctaatagtt
     9661 atttagatag aagcctatca catcaacttt ttagtagaaa agtacatgtt ttgtcttttt
     9721 tgctaatagc tgaccctttg agaaacttgg gttcaaaagt tgctaaattc ggtaaatgtt
     9781 ttggtatttt tcgtattata tttgtcgtca agctgactac taaattttgc cctattttga
     9841 cgacactgat agtcaatgtc ggacaatcta ggacaatttt taagggaata tgattgaaaa
     9901 atggtccaaa acagccaaaa atggcttaaa actgtgatag agaaaaaaga aaaagccctt
     9961 gatatacaag gactttt
//
LOCUS       DAFEML010000078         9748 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFEML010000078
VERSION     DAFEML010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.080"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            201..1592
                     /locus_tag="LP468_002336"
     CDS             201..1592
                     /locus_tag="LP468_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081834.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(1665..2312)
                     /locus_tag="LP468_002337"
     CDS             complement(1665..2312)
                     /locus_tag="LP468_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2081835.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(2320..3006)
                     /locus_tag="LP468_002338"
     CDS             complement(2320..3006)
                     /locus_tag="LP468_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081836.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(3012..4085)
                     /locus_tag="LP468_002339"
     CDS             complement(3012..4085)
                     /locus_tag="LP468_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081837.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            4307..4981
                     /locus_tag="LP468_002340"
     CDS             4307..4981
                     /locus_tag="LP468_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081838.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            4986..6326
                     /locus_tag="LP468_002341"
     CDS             4986..6326
                     /locus_tag="LP468_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2081839.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(6475..7461)
                     /locus_tag="LP468_002342"
     CDS             complement(6475..7461)
                     /locus_tag="LP468_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL2081840.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            8185..9216
                     /locus_tag="LP468_002343"
     CDS             8185..9216
                     /locus_tag="LP468_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2081841.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            9325..>9748
                     /locus_tag="LP468_002344"
     CDS             9325..>9748
                     /locus_tag="LP468_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL2081842.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT         3134 a         1759 c         1675 g         3180 t
ORIGIN      
        1 ataaacaggc gttacataat tttatttatt ttaatatgat aattattata cgaagggcgc
       61 taaagggaat cacaccaatt ttcataccaa ttggtttcat ttatgaagtt gattccttcg
      121 attaatgagc gtttcattga aagaaaaggg ttgagggaga aaaacatatg atcaggttgt
      181 tggaacgaaa ctatagaaag atggaaaaaa tcattcgaat tctgtccatt tctgacaagt
      241 ggatgactaa aaaagaactt gccaaacgaa ttggtagttc agaatctaca tttgtaaggt
      301 atatcgaaga gatcaaaatc cgctggggaa cggatgtaac gattcaatct tcacaaaaat
      361 tggggtatcg tcttgaacat ttgaatgtac cagcttattt aaatgttctg atggaaatgt
      421 cgcaaagttc tacaaacagt cgtttattaa atgagattat tgtcaatccg ggtaaaacga
      481 ttgagtatta ttgtgaaaaa atttccatca gccggtcttc ttttacacgt aagttgaaac
      541 aatgcaatca aattttagaa agctatttat taaaagtgat cgttgaccaa ggttttcagt
      601 taactagcct taaaagtgag ctccagttgc gtatctttgt tacctttttc tttttaagtt
      661 actacggaag acgcacgttg ccatttccaa tcgaaaaaaa gaagatcaaa gaaattatgg
      721 tcaagaataa ttgtcagatg aatttgtttc aggaagaaag cccatatgag caatctttct
      781 ttattatgta ttttgttgtg catctcatga gagaatccca aggaactcca tttgaatgga
      841 aagctggaga ctcttatgta cagttgataa atatcgataa aaaagacttc ttaatcttga
      901 aaaatctctt aggaaaattg aagtacagca gctatataaa agtagtgaac tattttgtca
      961 atacgatttt ttcagaattt tcggagaaag aaaaaaatga aatcagtgag cagatacgaa
     1021 aaaatatgtc ctactgttcg ttttcatccg ctgattgcaa agaaaaaaac gaagaatatg
     1081 ttgttcaatt attaacgcaa atttattttt tctcccgtat tttcccatac gatacgactc
     1141 atttgacgat ccgtgcaact tactttgcac agcagatgca acaccgccag atacgtctat
     1201 atgctggatt tcgtgcagaa cttcaatttt attccactct actgaatcag aatctgattt
     1261 attatttatc tagctatatc ttttggatgc ttatcggtaa tcctgaaatt caccattata
     1321 cttctgataa aaaaatactg attatcagcg acttaagtct tcgacatagt caatatattg
     1381 aagaatatat cagtgatatt cttgctgtgc ataaaattca ctctgagaca actgctatta
     1441 ctgaagatca gctgtcgaaa tacaatcttc tcgagtatga tctgatcgtt acgaatcaac
     1501 ccattttgaa tgcccatgtt cctcatatat tgattgatga tagtgtgtca ttcgcaaatg
     1561 aagaagaact catccgctta ttcgagttat gaataatcaa aaaacagcta tgtataaacc
     1621 accctgataa aaatttcagg acaaatacac atagctgttt ctttttattg tattccttca
     1681 gcaatccaac gagatttata gcgaaagtct tttaacaact cttcttttgt ccaattattt
     1741 gcaatgagat ccgtcaaagt gttcattacg agggtcatgg aaaagtatag gaaactaact
     1801 gcttcttccg acgattgaat ggagaaatga ttgattctta ataattccag ccatttttcg
     1861 ttcattggag aatcagccga tagttctcta cgtttggttg tctgctgatc atttcgctgg
     1921 gttaacaagt ataacctttg ccaatagata ctttcgtgat ctaagtcgca gcaccactct
     1981 aaatattttt cgatccccaa aaagaaatgt tgtttgtttt cgctaatgaa ttttaagata
     2041 tcttgatgga ctatgtgaga actgcttttg atcgtataca aataagcatc ttccaaatct
     2101 tgaaaatatt tataaaaagc accgcgcgac atccccatct tgtcaacgat ttctgagact
     2161 ttgacttggc tgatgtgctg tgagcaaaat atctccagta ataggtcatc gattctctgt
     2221 ttctttgcgt tcgataaatt gaaaaaagtt tcttttggca tccacatctc tcctttatct
     2281 ctgattatac gtggatagcc cttcattgtc atgaaggatt cattccttct ttttctcttc
     2341 ttctgtcaag tacccatctt ccattcgata aacgcgatca ctccattgaa tcatacggac
     2401 atcatgagta accataatag tcgctttttg tttctcatga gcttctttaa ctagtaattt
     2461 gacgacttca tatgcatgat ctgtatccaa actagctgtt ggttcgtctg ctaagatcaa
     2521 gcttggctca ttatataaag cgcgagcaat tgccactctc tgtctttctc caccagaaag
     2581 gtctttagga taactatttt taagtgactg gatatctaaa gattgcagca aggaatcgat
     2641 ttttgttgaa tcttcttttt ttgaagtaac ttggtcaact agttcaaatt gttcctttac
     2701 cgttaaaaaa ggaatcaaat tagagctttg gagaataaat cctatttctt taaagcgtaa
     2761 atctgctcgt tttttttctg gaagctcagt tagtgagtga ccgttgatca ctatttctcc
     2821 ggaagtcggt gtttgcaatc ctcctgaaat ggtaaggaaa gtacttttac ctgaaccaga
     2881 aggaccaatg atgctgacga attctccttc ctttacataa aaatcaattg ctttcaaagc
     2941 tgagaccttt gtatgaccag aaccaaatgt tttggtaact tttttcatcg ttaatatttt
     3001 tttcattttt attaacctcc tattgctgta attgggtcta ctttggttat cgtacgtatc
     3061 gaaaacaatc cgcctagcat tgcgacaatg atcaaaatcc cactatatag caaccattgt
     3121 gaccaaaaaa cagcaaaagg catcgcgctt ggtaaaatca gactagtcaa ataagcaaac
     3181 aaaagagcaa gcagaacgcc taccacccca acaataaagg actgtgctac taaagattta
     3241 gcgatgaaga aatttttgat cccttgtgct ttcattactc caaaaatagc agtcttctga
     3301 agtgtcatca cgtacatgaa aataccgacc acggcagcaa ccactaagaa caaaaagtat
     3361 atcatcgcat ttaaggtcat attttgggca gaatagccag gaatactttc aatgaatgtc
     3421 ccaatagtta ataactgtag acccttcgat gctttttctt tcgaaatttt agctgaatcc
     3481 tttattacga tcccattgat cggctgttct tcttcagaag caaacggctg ttgtccatac
     3541 ttcaaagcag tccacgtatc tagggacgca tagatgacgg gagaaactgt gtaataagtt
     3601 tcaggaaaga taccgacaat cgtcaaagga tcgtcgtaac tgccaatttt gatcgtatct
     3661 ccaattttat agcctgaatc agccagattt tgagagatga tgatttcatt ctttgtttta
     3721 aattcatgcc ctttcgtgag ttttggtaat aaaaatgctt ctttcgttgt gccgaaaact
     3781 gtaacatttt ctttgttttt tcctttgatt gctccgctgt acaatccgat tggtgctttc
     3841 tctcctcctt caatgtattt cagatctcct cttgttaatt gtgaagctgc aaatacttga
     3901 tttgcatcct ccgacaaaac aatctcttgt gcgtcccaat catcgattgc ttttttaaac
     3961 tcttctgaaa gtccattcgc tagtcctgac aacatgaata cgacatacgc aatcaagaac
     4021 ataataccga cgatcaagcc atatcgtaat ttagaatagc gaatttcttt gatagctaga
     4081 aacatttgtt tttcctccct atgatagatt gatagtgaca aaatgtcact tgttgaatag
     4141 tgtaactcta aagtgacaat ttgtcacttg tgttgttttt ttcttatcaa taaattgtct
     4201 aagacatctt tcgataaaac cttaacatga gtcataaaaa atttatttaa gccttattta
     4261 tgctttccat gataaactaa agtgaccaaa tcaatgaggt gggaaaatga ttaaactatt
     4321 agtagtagaa gacgataaag tattatccaa taatataaaa gaaatactcg ctgcaatcgg
     4381 cgagataaca caagtttatg atggtagtga aggactgttc gagttggaaa gtggagttta
     4441 tgatcttgca atcttggatt tgatgatgcc ggaaatgaat ggatatgaag tgttagcaaa
     4501 aatacggaaa gaaaaaatac agactccagt attgattttg actgcaaaag atagtttgga
     4561 agataagatt gaaggatttg aacgaggtgc agatgattat ctaacaaaac ctttctatcg
     4621 agaagaactg atcatgcgcg tgaaagcatt attgaaacgc tcgctaggtc tctttgatga
     4681 aaatgttctg aagtataagg atatcagttg tgatttaaaa agcaatgaag tcttgtataa
     4741 agaacaagtt ttgcccatac aaggaaaaga gtttgaattg ctcgtttatt ttttacaaaa
     4801 taagggaatc attttgacaa aagagcagat atttgaccgg atctggggat ttgattctga
     4861 tacgacgatt acagttattg aagtttatat gagcaactta cgaaaacatc tgcgaagtac
     4921 tggattggat aaagaaatca aaaccttacg taatgtcggt tatatactgc aaagggtgtg
     4981 atgcaatgaa tggagatatt acacgaaagc aacgtagtcg cttttttgcg acaaatgtag
     5041 cagcatttgc ttttatcttt tttcttttgg gattcattac tttacagata ttaaaccaat
     5101 ctgcatacag agaaacagat ctgtcattag agaaaataaa ttttgattct cgaacagtac
     5161 aattagagat acaaagatat cagcaaggcg atcccttttt aaacccgact caaacggaac
     5221 aaaacagaac aaacatggaa cagccattaa tggaaccatc aaatgaccgt tttaacactc
     5281 aagtgatctt gtggtctaaa aatggtgaga tattgaataa agcagctatt ggtgggcgtt
     5341 tcaaccaaat caaagaatta aaaatggata cgaaaaatct gaataccatc caaaatattg
     5401 aattaaatga agacagtggc tcatctgccc tctctttccg ttcgattacg aaaaaagcgg
     5461 agacgaatca agatggcgtt gcctacatcc aaattttaga aaatacaaat caaatcaaga
     5521 attcattagc gacttttcgc acgattatga ttttgtgtat gattgttttt tggattctct
     5581 ctattggtat cagttattac ttgtctagtc taagcatgcg ccctattatt ctttcttgga
     5641 gaagacaaaa agaatttgtt gagaatgctt ctcatgaatt gcgcacaccg ttaacgatta
     5701 ttcaaaatag tttggaacat ctttttacca agcctaatca tactattatt gaagaatccg
     5761 aaagcatcgc tcaagcattg tcagagacga ggcgcctcac tggattgact tcggatttgc
     5821 tgacaatcgc tcggaatgat tctgatcagc agctgctttc aaagcaaatg atcaatacac
     5881 aagaatatat cgaacaactt gttaaaccat ttcaagagat ggccatcata gatggaaaag
     5941 agtttattct ccataacgat gcaacattag aagtaccaat tgatgaaaaa aaaatccatc
     6001 aagttttggt tattttgctg gataatgcat taaaatatac gaatccagaa gataagatca
     6061 ttttggattc atctgttaac cataaagaat ggctgattca cgtaaagaat actggccctt
     6121 ctatcagtga agaagatcaa gcaaggattt ttgatcgatt ttatcgggaa gatcaatctc
     6181 gggcgaaaga gactggcgga tacgggcttg gcttggcaat tgcaaaacag gtaatcgaac
     6241 agcatcatgg acagatttct gtatccaatt atcttccaca aggagtcgat tttaaagtcc
     6301 aattgccgtt gaagcctaaa aaataatgct tatccctaaa aaagggctgt gacaaaaatc
     6361 ttgtcacagc ccttttttgt tgcgaataaa cggtgttcca gaagtagctt cttcggaaat
     6421 aagccgaaat ttctttaagc tgaccacttc tgtcacaacc tctttagctt acgcttacga
     6481 ttttttattg cggtcttcaa tgtgtacatc accgcttgtg tcaatatcca attcttctcg
     6541 gctaacatct tctgtcactt tttcaacatc ttcatgttct tctttatgaa tcccaacttc
     6601 ttcacgaata actgtatgtt tgcttacatc tacttgctct tctttgattg ggatagtaat
     6661 cgtgtcatct tccaattttt cgtctgttcc ctgtgaagat tgatctgtta ctggtttgcg
     6721 ttcgatgacg atttcttcac gtttgaccgg tacttctacc gtttcagtat cgttgaccac
     6781 atgtttgtgg atgtcgactt ctccagttgt cacatcatgt gtatttacat ctaatttttc
     6841 ttcttttagt tgaattgtat catcatctag atttggtttg cgatcgatgt cttcagtctt
     6901 gcttgtaccc attgtatcag tctcgccagg tacgtccatc ggatcagttc ctggtgtcat
     6961 attcaatgga tccgttgtat tttgaaagcc tgtcgtgcca cctacgtcca ttggatctgt
     7021 tccagtgcca gtttctaatc cagtccccat tgtgcttgct gggctaacag tatcttgtgt
     7081 atccattgta tcttctgttg tttctggctg acgatagcct tttactgtga tgacaaattt
     7141 tccatcagaa atatctcctc tatattgata taaaggatca ttttctggtg tagccgtctc
     7201 agaatcatag gtatcaaaag aaaaagtatc ttttattttt tcccataaag aacggtcttc
     7261 ttcaccatcc atccgatttt catctgtttc aacatctata ccagacaatc cgtcaaatcc
     7321 tagtctagat gctgcttcat cagtagtata aataacgata tcatctcgtt catacccttc
     7381 gttacgcaac cgttcaatta ctgataatgc ttcttccctc gtactatagc ttccgatgac
     7441 cgttaaattt ttctcttcca tgtaaattcc tcctagcaaa tagatttatg attggtatat
     7501 tgttacttat aaatttattc tataggagac gattgttttc tacaaatatt tagattggaa
     7561 tttgattaaa acaatttaat tgaaatttga aaacatttat gttaatgaaa gtcatattct
     7621 aataaaatgt catttgtttc tatatgaatt tttatgaaaa atttcatata atttccactc
     7681 gttgtgatgg tttaatttat ccaatccatc aataagcaaa caacttatat aaaaaaggat
     7741 taattctcaa tataattgct cctaccatag aataaatctt catgtaaagt aatgaagtac
     7801 caactatttc taatacttct ttaagaatta tcccaacaat atcgttagac aaaccattat
     7861 tgaataaatg gagagccaat cgattctgaa aaaatgtttt ctaatttttc ggaaataaaa
     7921 gaaagagcct cctgccatta gaacgaacca aatccatttc attgctcatg aagtaaccac
     7981 atagctaaaa agaggataaa tcaattaaaa gatcaaaaga atgactgcac taataaaata
     8041 actaaaaatg tatcttctta cttcatatct tttagctagt acttagttaa aaatttgctt
     8101 cctaagatca agacaaactg tctatcttca tttgatgaaa tgcggtaaaa tatagaaaat
     8161 gaacactatt ggagggaatt tgtaatggac agcaaaacta gaaaacaact gcaagaaaag
     8221 ttaaagcaac gtacacactt gctcccttcc gtctttcaac agtttttaga agaaaatcgt
     8281 tcttcccttt cattaggcag tcgctatgaa tacgcaaaag attttcatct gtttactgat
     8341 tatttgagaa aagtattttc tgaagaagtg gatgatcagc tgattatcca tttagaaaaa
     8401 caagattatc agaatttctt agctaaaatc tatcgacata ctcgttcgtt ccaaactaca
     8461 gcgaaccaag aaacggagca attgtttgaa aatagctatt acgggatttc aaggaagcaa
     8521 tattcattaa atcatttttt acgatttttg tatcaaaaag gactgattga agaagagatt
     8581 tctcttttgg gtacaagttt accggaaaca accaaagcag ctccgcgata tatcgatgca
     8641 gaacttttca aagattttga gcatttgttt atcccgattg aaggctttca aacaagcaga
     8701 gaagctagct ttgaagaaaa gaatagaccg aggaaccttg caattactgc cattcttctg
     8761 tattgcggat taaagatcca tgaagtagta gaacttaaac gtaaagatgt atctttgacc
     8821 aagcagattc ttaatctgaa tagaaaagaa aacagactga ataaagtacc aataccaaaa
     8881 gaagcgatgc catttctgga gaactatttt aagttaacag cacaaaatac ggacgaaaat
     8941 tcttttgttt ttcgttcctc acatgatcag caaatttctc ctcggactat tcgccaaatt
     9001 ttgagcaaaa ttacagtata taaaaacgta tcgccagaac tatgcagaaa aacatatcgt
     9061 tattatgcag aactatattt agatgatgct gacgcggtaa attatttatg tggtaatcga
     9121 tacctctcat cccattcttt tcaagatatc tgggaaaaga tggttgattt ttcttatcac
     9181 gaattagcgg cattcgttcg ggtttcttcc atataaaaca aatgtatgat ctttttttca
     9241 caataaacta tgttattata taaaggatta tgttacgatt atcttgaatt tgtatattac
     9301 ttaacaaaag ataatggagt gtgaatgatg gagaccataa cgtattcccc tttgaactta
     9361 tttacgaatt ttcaagaagc tgcagctaac ttttccgaga ccccgattat ctttgatgag
     9421 ccactttcag ctttcccaga attaggactt gaaacaactt acaaaaaatg ctgcgaaagt
     9481 gtgttgaaac gggcttatca attggctcat cttggagtga aatccggaga caaagttatt
     9541 atttataaga gttccgcttt tgacacatac cttctagctg tttctgtgtc ttaccttggt
     9601 gcagtgcctg tcatgacttc ttatcatcta ccaacaacaa caatggaagt atttatcgat
     9661 cgtttagaag accctttcat tttatttgat gatgagacaa aaaagcgagt gagagaaatt
     9721 tcaaatggaa caaaatcaaa acagattc
//
LOCUS       DAFEML010000079         9566 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFEML010000079
VERSION     DAFEML010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.081"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..359)
                     /locus_tag="LP468_002345"
     CDS             complement(<1..359)
                     /locus_tag="LP468_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL2081843.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDIL"
     gene            complement(560..1429)
                     /locus_tag="LP468_002346"
     CDS             complement(560..1429)
                     /locus_tag="LP468_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2081844.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(1449..2570)
                     /locus_tag="LP468_002347"
     CDS             complement(1449..2570)
                     /locus_tag="LP468_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL2081845.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(2572..2967)
                     /locus_tag="LP468_002348"
     CDS             complement(2572..2967)
                     /locus_tag="LP468_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2081846.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(2986..3792)
                     /locus_tag="LP468_002349"
     CDS             complement(2986..3792)
                     /locus_tag="LP468_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2081847.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(3785..4573)
                     /locus_tag="LP468_002350"
     CDS             complement(3785..4573)
                     /locus_tag="LP468_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2081848.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(4587..5063)
                     /locus_tag="LP468_002351"
     CDS             complement(4587..5063)
                     /locus_tag="LP468_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081849.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(5135..7792)
                     /locus_tag="LP468_002352"
     CDS             complement(5135..7792)
                     /locus_tag="LP468_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2081850.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(7811..8215)
                     /locus_tag="LP468_002353"
     CDS             complement(7811..8215)
                     /locus_tag="LP468_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBL2081851.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(8447..8704)
                     /locus_tag="LP468_002354"
     CDS             complement(8447..8704)
                     /locus_tag="LP468_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBL2081852.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(8829..9161)
                     /locus_tag="LP468_002355"
     CDS             complement(8829..9161)
                     /locus_tag="LP468_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081853.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         2989 a         1925 c         1349 g         3303 t
ORIGIN      
        1 tctaaaatat catcagtggt catagacaag gcgattttta atttttttag caacacattg
       61 ttgatatatt tgatttcctt gcttttttgc ggcgtgtcta ctatcggctt atctttttgc
      121 ggaccacgcg ccaagagaat caggccattt aggaatgcgt caaaaacttg gttgttgatg
      181 gttttttcat acacattatt ttctgcatta tctttgttct tatcctgtac tttggtcagt
      241 accgcctgag cttcttcttt agtcagtggt acaccgccta gctcaaaagc tttaatcaaa
      301 tccgtatctt tcaaatcaat cgcataacgc aatcgcaata acctatcatt gttattcatt
      361 tgttcctccg aagtatttag tctttacttt cttacgtact ttttgtcttg ctaagatttt
      421 taggatcaat gataaaaacc gcatcactta tgataaggcg ctgggtatca tgagtgaatg
      481 atattgctga atacaaatag tccgaccaca ttaagttgat cggacttcat aagcatttta
      541 ttgactaata cttttttgct taagaattga ttctaacatc ttttgctaaa gttaagcatc
      601 ctatagttcc tgcattatct gctaacttag gtgtgacaat gtattcttcg atatttggcg
      661 tatcgacata gccgttaatt agttctaaaa aacgtctttg tactttcttt ttcagatgtt
      721 cttgttgcat gacaccacca ccaaaaatta taatatctgg tgaaagcatc agggtcgtat
      781 tacaggcaca ttgtgcaata taatccgcct cgatttccca gaacggatct tctatagaaa
      841 gatcttgtcc cttggttccc gtacgcatct cgatagcggg tccagatgcc aacccttcga
      901 gacaatcatg atgaaaagga caagtaccag agaaagtatc tcctgaatgt ctcttaacta
      961 acgtatgccc catttctgga tggctaaacc cttcaacaaa aatcccatct tgtatagctc
     1021 ctccaccaat tccagttcca acagtgtaat aaacaacact ggataaacct tttccatgac
     1081 ctgaaacata ctccccgtaa caagcagcat tcacatcggt tgtccaggca attggaattt
     1141 cgaaatgctt attcaacgtt ccaacaaaat caaaattttt ccaggcagtt tttggagtag
     1201 aggtgatatg tccataggtc tttgattcac gatggatatc aatcggtcca aatgacccta
     1261 ctccaatgct ttctaattgt tctttatagt gattaaagaa atcaattacc aaactcattg
     1321 tttcattcgg tgtagttgta ggaaaactca ctctttctaa aacctttaaa tcatcattgc
     1381 caatggcaca aacaaattta gtcccacctg cttctattga gccatacatt tcttactcca
     1441 ccgtcctttt atctaggaat tcgttcttcc ctgtctaata gtttttcgaa aaactcatgt
     1501 ggttcctttt ggtaccaata ggcaacagaa gaaatatcgt cttgacgctc ataaagcttg
     1561 atgtcatcat ttcctagggt ttggaaagta acacgtaaat tttctttgaa actaatgggg
     1621 tcgggtaaat gccagcggta caacccatgc atcggtaaag catcatcgcc aaaaccatga
     1681 actggatttg gattaggttt tccagcacta aaataatccc gggtgtgatc tcttttagat
     1741 tgaaaaggat agcccataaa tagcgtatta aaattttgag catatgccct ttctccaaag
     1801 ttctttttat ggaaagccca agcgccgcca aaataatctt ctgctcctgt agatgttatt
     1861 gtagggaaat cttcatctcc atctatataa aacttaaatt ctccttcccc ccaccagtat
     1921 ctttccaatg cgcacaaagc aaagtaggtt cctacataat acccagtgcc tttgattcca
     1981 tcaataaggg tgtaatcttt tccttttgtc gtgatgggtt cacggttcca tttagcatga
     2041 aaatacatcg catcatccgg tacttcagtc aatgcataat taaatgtata aaaaatgtgc
     2101 ttaataaact caggatgttc attcgttaaa gtaatcttag ctttttttcg aaatggcatc
     2161 tcaaaatagc aattcatccc tgatgttgga ttcactacga ttggtaagga attcacttcg
     2221 catcttgtcc caaacccatt acaaaaaaaa tctcctaatg gactttctac agaaggagtg
     2281 gattcatcat cccaataaat acgcaaaatt aaatcacgta agacgaaact cccagcgatt
     2341 gttttgtctg tcactgtcat ccaaaaatga cgtaaaattc cagggccttc catttctgct
     2401 aaagtaattg tctctccagc atttatcgga acagaaggtg acccttttct cccaattcct
     2461 agatgactcg ctgtcattgc cgctttccct ttttcaccat ttttattttc tggtgaaata
     2521 gttctacttt cctctccctt gtggagccat atattattta aacaattcat tttattcgtc
     2581 ctctatcctt tcttcacttt tttgattatt catatagatg atttgttgtt gtgcctccgc
     2641 aataattgct ccaatatcta aattatcatt tcctaactgc aaagcgattg acattgccaa
     2701 gggaagattc attcctgcaa ttacgtgcac tctgtcagaa atataggtaa aaaacttttg
     2761 atttacactt cctccagcca tgtcagttaa aacaattatt tcgtctgtag tatccactaa
     2821 ctctttaatt tgttcatcta tatcatcaat ttcttcgaca tatgcacata agctactaat
     2881 ttgattatgc atacctgtta aaaactctag tgtctcttta aaaccctcag ctagtattga
     2941 atggctagca atgatcaatc ttctcataat tcaaatcctt ttcctttacg ctaatattcc
     3001 aaatgcagcc ataaccatcg caaaaacaat aacgagtaga atcaaaatgg tcatactgat
     3061 ttttttctta ctgagtagat aatatgctgc agcagtaata attactggaa ttaatgttgg
     3121 taaaattttg tccaacattg gttggatttt catactaact tcaccaaaag tgaatttaag
     3181 tggcgttgaa acactgataa ctgaagcaat taatgatcca actactgtta gccccaatac
     3241 tgaagcagct tcagttaaat aattaatctt ttcaccgtat tcagtaacaa tcttcattcc
     3301 ctgcttataa ccaaattcaa agcctctcat tcggaaaaag aagattacca tgattaaaat
     3361 gaaccataaa aagattccta caggattatt ttctaaagcc atataagccg caattgatcc
     3421 catgatggtt gggatcatcg tcatcaaaag agagtcccca ataccagcaa ttggacccat
     3481 cgtaccaact ttaaagtcat taatcgcatc ttttgcttct aatccttgct tttcctccat
     3541 tgcaacacaa gcacctaaaa taatggctgc cagccaaggc tgtgtattgt aatactgaaa
     3601 gtgattattt aaagcttcga tgtattcatc atcatctttg tataattttc ttaaaatagg
     3661 tgacaatgcg taagtcacag atgcaccttg ctgtgtttga taattaaagg tacaaactga
     3721 catcaaccaa cgatagttcg ctttcctaag atcctttttc gttacttgat atttttcgct
     3781 cattttattc atcctcccca ataaacccaa catcagaagc tcccgcagaa gcagtgattt
     3841 gtgcatcttt ttcagctcta tgatacacat taaatgctaa agcgaatcct atgatcgccg
     3901 ctccaataat aggtaccttc aaaaaagcgg ctaagaaaaa tccaacaagt aaataactaa
     3961 tgtatcgacc tgtaggcata aagcgtaaca acatcgcaat accaacagca ggcaacattt
     4021 ttccggctaa tgttagccca tccataaacc aattaggtaa aacatccaaa acgtaattaa
     4081 cagcagactg tcctaaagta acggcaataa atactggaat tgctgcagat aaaccaaaga
     4141 aaattggccc caaccacaaa acactattca ttttcttaaa ttctcgttta ttcgcatatt
     4201 cctgtgattt gcgaacaaca aaaccattta agattttgac aattacatct agttgcaccc
     4261 ctaacatacc tacaggtagt cctattgcta atccggcttc tactccaagc tggctaccaa
     4321 atgccgttgc aataattgcg cacgttccat agtccggtac agatgagcca ccaaaaccgg
     4381 caactcctaa tgacatcaat tgaactgtac cgccaactat caaacctgtt tttatatcac
     4441 ccatcaaaat tcctgtgaat aatccccaaa aaactgcgta atttacaaag atcatcggaa
     4501 tcccataata atcaacatgt ttaataaatg ctaatatagt cagcataata atttgaaaaa
     4561 tagtaaaatg cattatcctt actcctttat cctaattttg attgaatttc ctgtgcctta
     4621 tccgccggaa caaattgtgt aacaatttct acaccagaat ccaacaattt tttatacgtg
     4681 ctgatatttt catctgatgc ataggctcta gaagatagct gtaatgcatt atctttaaca
     4741 acagtaccgc caacaattag tcggtcaatt ctaataccgt tatctactaa atgaaggatt
     4801 gtttccggct ctttcacgat gacaaatact ttttcctgat cgtatttccc ctttttaaaa
     4861 ttcgcaatcg ctgtttcttc agtgataatt gatacagcca ttccagcagg tctagctaaa
     4921 cgcatacttg atttttggat gtcgttattt gcgacagaat catcgatcac catcactctg
     4981 tttgctttag acattggtgc ccattgcgtg acaataatcc catgcaataa acggttatca
     5041 actctcgaca taacaatact cataaatact tcctccttta tctttcattt tcttacaagc
     5101 aattaccatg ccaaaacaaa aagaacttga taaatcaagc tctttttaca taatcataaa
     5161 cgtatttaac ctcatgaatc gggatgtcga cactataata atgttcaacg acactgaaag
     5221 attgcttaaa atgtgtctga aatttttgaa attcctcact cgtttcattg aaataaattt
     5281 catcttccaa agtattttgt tttactaatc gttcaattaa gcaactaatg tgaacatata
     5341 atccgaaaca cgtattatta tcaaatgaaa ttcctagatc attttgtaag atgtatatag
     5401 catctgaaac ccgttctaat aatttagtcg gatttaatat ggtcaattgc tccattaaat
     5461 tcgttagact aaaattcttc agaatattat tgttcaaaac tttcagttca ttatcattaa
     5521 agtgtctatt caattgattg gagaatttac ttatattcat tcctaaaatc atatcttcaa
     5581 ttgaaaagaa ttctacatct tctagatgtg gatttagtgt tccaacaata aaaagaatat
     5641 tgttctcttt acgaagctcc gataaatagt tttcattcac taaagagtaa tagtcacacg
     5701 tttctatgac aagatcagta tcccttggaa agctatcttc aagtatcctt tttaatttaa
     5761 acgaagttcc taatccgctt gcacaagaac agacaatcat atccttctta atatttgatg
     5821 attcataaat ataatccaca ttttgatttt cttttacttg ttcaagaatc tgtttaagcg
     5881 gtaaatctaa taatatctga tttgcaacat caatagccat tcttgttgaa acattgttta
     5941 gtagtccgaa ttttttttga gcgtctagtt ccaaatttag ataaattttc tccagtgaac
     6001 ccatatcaac aagtaaaata atttcttcat atccggtaca ctcttgtaag tatctattaa
     6061 ttttgtctgc aatctcacta cttgaagtca ttagtggcat atcaatggcg tcgtatatat
     6121 atctctcaac gatcctatta gcagtacttg ctatacaggt tgccgttaga tctccatgag
     6181 ccaaaatcag tgctaaacgt ttttgctgaa attctttact acacattaac ttaaataaaa
     6241 taaccaaaac atttttttga atttttgtta aataaatatc ccctatttga ataaaacgat
     6301 tgactaattg aacttctcga ctacaccaac tattaatatc attgatgaag gaatataatt
     6361 tatcgtccga tgttaattgg atttgataaa tccaagaatt caaaaagata gacgttattt
     6421 gaagataata atagtcaaat tctatttgaa aatctctctc tatttcctta acatactgtc
     6481 taaatcgaat ctcttgatag gtgggatatg ttaaagctga attattttgg atatcaacat
     6541 tcttttgtct aaaatatcta tcatatttct caaaaagctg ctgcttatca gtgtctttct
     6601 tccacgtttg ataaagatac tctataagtt cgttgatatt aaaaacttcg tctacttttt
     6661 ccaaatcatc catttgaata tattttaatt cattctgtct tttcataacc ttcatgccgt
     6721 tgaaattcac ccattgtggt aaatgataca tctgaatata aagttcttcc aaatcatcta
     6781 agaaataaaa ggcattggca caggtcaatt gaatgatatt tttcaaattg ccaacatttt
     6841 cactaaagcg atagtttaat aaaaaatcta ataattgttg agatatcagt attttctttg
     6901 ctagtctttc ttcttctgat ttaaaaaata tcttgattaa ctgttttctt tcataaagag
     6961 aacgactgtc taatgttgga agtgttagct ttacaggtat tcttctcaac aaagttgata
     7021 atagtttatc ctcaggtggt tctgatgttg caaatataat ccagcaactt gatgtgtacc
     7081 agttttcatt atcacccatc cgatgaaatt tcctcgtatc cataaactga aaaagtttct
     7141 cctgacattc attgctcaat gcatgaattt catctaaaaa taagactcca ttattagcta
     7201 attctgctaa accctttctt ccatcttcgg ctcctgtata tgcacctttt acatgcccaa
     7261 aaaaattgga caagaaaagt tctggattat tggcatattc actacaatta actgaaatga
     7321 aagatgcctt ctcttctata taattattgg ccaacaaatc cttatacaca taatttgcta
     7381 aatagctttt tccagttcca gtctcgccat gaagtaaaat gggtaagcca tttggcggat
     7441 agtagattgc tgctttaatt tgagcaatta catttcgcag acttccttga cttccgataa
     7501 ccctttctat tccaacccta aaagagctat cataccattt ttccgcttcc tctgaagagc
     7561 taaaaatttg ttgatttgga actttctccg gtaaagaaaa gaagattact ggacgagtat
     7621 tgatttttcc aaattctcca tcttttacga attcattcaa atattgagag acaatattac
     7681 gactaacatt taatttttca gatattttct gtgctgtatt gttcccccat ttatttttaa
     7741 tctcagagtt ctctatgaca taattgacaa tgcgttcttt taattcttcc atcacagcac
     7801 ctcctcgaca ctattcgaat tttgccgaca gtatttttcc ataaatatga cttgctaaaa
     7861 aggctttgtt tagatcattc aattggaacg ttgcttgttt tgcttgatcc gctaagacgt
     7921 tgaaaagata ctctggcgaa atcgcatacc ccaaaatatc aacgattgtt gcaatcagat
     7981 cttcttttga ttcttcatct gaaagtaatt cacgatacaa catcgtttgt ttgcttactg
     8041 tgtcatattc ctctaaggat tcatctgcta aaagaaccac ttgttccaac aaacggtcgg
     8101 ataaatattt atagaaaatc agccccaata aataattttt atattctgac gcatccattt
     8161 tactacggag attatctgcc gcactaaata acttctgatt taattctgca cccaaaaaga
     8221 tacactccta tctcttattt aaagttgcta tataccctct tattttagca tactcagttt
     8281 tagaaaaagc aaaaaaataa agaaacttat tcttgataac aagctacgtg acgtatatcc
     8341 ctaacacaaa aatagccata tcctttggtt tggatacggc tatttgatat tactcattca
     8401 attatcaaat cacagtaggt gtgaatctca tcgggatcgg caatatctac ttctgattag
     8461 gatcaaaggt gattttctca ataaaggtgt gatacaaagc tttaacttgc ttcttctcac
     8521 tctggataag aaagcaatcc aaactagtca atatctgttg gacatctttg acttgaatcg
     8581 gttccccttg ttgttgaaag atccctaaga tttcattctc tcgaatttgt aactgtcttc
     8641 gtttttcagt caattcattt aaacgatctt ttaacatcgg aaacaattcg ggactatctt
     8701 ccaaagcagc ttcctgtttt tgctctaata gttagatttt gcgtaccatt ttcttctttt
     8761 attttccttc gattgctgat tttaatatag tctaaaggaa atttatattt attgtattct
     8821 ttataacttc aagagaactt cgtttgagta ttactgtatt tttttaattc cataagaaaa
     8881 ttagttatta cctgccacct aatcagcaaa tctgaacctg agtcaatata attaatatta
     8941 ttttccatct ccaacattgt aagtactgtt ggtgttaata tagggacttt gtacaattgt
     9001 atttttttga ttttatcatc tgcacaaagg agatttttta aatctaatcc ttcttttatt
     9061 tcaaaagttg aattttttaa atctataaga gtaaaaccaa ttccttcata ctgaatttct
     9121 gaaaatcgaa tttttctccc agttgataga tcaaggggca gaaaaccttt tattacattg
     9181 tgagtgtcac catcatttac aatgtcatta ggaattttga ttttagaatt ctgtggagca
     9241 cctattggaa gataataatt cattataatt ttgtagtctt catgaggaaa taaagtactt
     9301 ttaggattgc taagatattc tcgtaccgaa tctaagaatg gcttatccat tgaatcttca
     9361 tccccattta aactaaaaaa cattcctaca attgcttttg caactctaag tgaattcatt
     9421 ttctttattg aatgtgttaa atcagactta ccattcttta aacttgtatt gttataaagg
     9481 aaatttttat tgtcttctgc aaatctaata tattcctcaa catactcact accaaaaaaa
     9541 ctattacatt tactacataa cgtatt
//
LOCUS       DAFEML010000080         8740 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFEML010000080
VERSION     DAFEML010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.082"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            163..2091
                     /locus_tag="LP468_002356"
     CDS             163..2091
                     /locus_tag="LP468_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL2081854.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            2217..2771
                     /locus_tag="LP468_002357"
     CDS             2217..2771
                     /locus_tag="LP468_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL2081855.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(3256..3570)
                     /locus_tag="LP468_002358"
     CDS             complement(3256..3570)
                     /locus_tag="LP468_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL2081856.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(3584..3844)
                     /locus_tag="LP468_002359"
     CDS             complement(3584..3844)
                     /locus_tag="LP468_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL2081857.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            4014..4328
                     /locus_tag="LP468_002360"
     CDS             4014..4328
                     /locus_tag="LP468_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2081858.1"
                     /translation="MNLLFQSIKSITVPELKEKILENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4330..5985
                     /locus_tag="LP468_002361"
     CDS             4330..5985
                     /locus_tag="LP468_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2081859.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            6068..8203
                     /locus_tag="LP468_002362"
     CDS             6068..8203
                     /locus_tag="LP468_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2081860.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            8378..>8740
                     /locus_tag="LP468_002363"
     CDS             8378..>8740
                     /locus_tag="LP468_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081861.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
BASE COUNT         2949 a         1497 c         1822 g         2472 t
ORIGIN      
        1 tttatttggt gtgcttatga aacggtacct gtcaggaaaa caatatcttt gtattctaat
       61 aaggatagga catgactttt ttaagctgtg ttctatcctt ttatttatct ctaggccctt
      121 atttattttg ggacaggtat ctcttcaaga aaaggagaga atatggacaa cgaaatgatt
      181 agtcaattac aatttgatcg gatcaaaaag gaaatccaag caagagcaat tggaaactat
      241 agcaaaaaac gaatcagcga tatgacggtc tcgacaaacc tacaaactgt cttggatcgt
      301 caagaagaaa caagagaagc acgcttgatc ttagaaagca gtcagcatgt tccatttatg
      361 gggttgccga ggatcgatgc actgacagaa caagtcaaaa aagggttgat tctgcagcca
      421 accgatttga tcgaatatgc ggattttctt agaagcagtc ggatgatcac aaagtttttt
      481 gataagaatc aataccagac acccttgttg tttgcttata gcaaacatct tcctgatttg
      541 ataaatgtag aagagttgat tgaccagaaa ataaaaaata ataaagtcag tgacgacgcg
      601 tcacgtaatt tgcgtaaagt acgcaaacaa ttacaactaa tcgaaaaaga aatccagtca
      661 aaattactga aattcttgcg tcatccgaaa aacaaagaaa tgatccaaga agcaatgatt
      721 gttcaaaaag gcgaatacta tacgattcct atcaaagcca gctataaaaa taaaatagat
      781 ggaacgatta tcgatgaatc aaataaaaga acgacggttt ttattgaacc aactgtgatt
      841 tctaaattga atgaacacta tcagttgtta aaagctgaag aaatcagtga agaatatcaa
      901 gtcctggcgg cattgactgg tgctatcgca gaaaacgaag aagtgatcga tttattgatc
      961 gaaacgatca cggtgttaga tatcatcttt gctcgggcaa aatttagccg agaaatcaat
     1021 ggaagcacac ctagaatcaa taaatcggaa catatcatta tcaagcaagg cagacatcca
     1081 tttttacctg agcatgcggt accattggat gttgaaatcg gtaaagacta tcgaggcttg
     1141 attatcaccg gagcaaatgc cggaggcaaa acagtcgtgt tgaagacagt cggtttattg
     1201 actttgatgg cgatgttcgg tatgcaagtt ccggcaaaag aagggacaga gcttgctgtc
     1261 tttgatgaga ttttcgtcga tgtcggtgac caccaaaatt tagaaaatgc gttgagtaca
     1321 ttttctggtc atatgcaaaa catcgctgct attttgaaaa agataaaaag gaatacgttg
     1381 gtacttttag atgagattgg cagtggaaca gagccaaatg aaggggctgc actagcgatc
     1441 gcaatcatgg aatctatgta tgagcaaggg gcattgatca ttgccacgac ccattatgga
     1501 gaaatcaaga aattcgccgg agatcatgaa gattttgtgc cggctgctat ggctttcgat
     1561 cgggaagcac ttcgtcctaa atatcagttg cgggttggag aaacaggaga aagccaagct
     1621 ttgtggattg ctcataaaat ggatatgtcg atgaaattga tccatcaagc agagcgttac
     1681 ttggcggaaa aagcctatcg gacacagaaa aaagaatttc ttcctaagac agcagttaca
     1741 aataggaagg agaataaaaa agaacgccag ctctttgcaa aaggtgatcg gatatttgtc
     1801 aatgaatacc aaaaagaagc gttagtttat gaagatatag gtgaagatac gattgatgta
     1861 tatttagaca aaaaaataat ccacgtgcct cgtcagcgtg ttcgtctggt gcgttcagca
     1921 gaagatctgt acccgacagg ttacgattta gacagtctgt ttatcgatta taaaacacgt
     1981 aaacggcagc gtgacctaga gcgaggatca aaaaaagctc ataaagtact agtaaaagaa
     2041 atgcgcaaac gacaggaaga aagaagagta aacgatgaaa acagcaagtg attatctcaa
     2101 attagctcat aatatcagtg gctgtaaaga aaaataaaaa cagtgaaatc attggtttta
     2161 ttccccgtgt aagctaaaat aaaaagaaaa gagtgctgag gaggtagggc gataaaatga
     2221 aattaagcac agactggcgt aaagaaatac aaacgattcc gaatctttta tcgatattcc
     2281 gtattttttt gctgccgatt tatctttatt ttgtgctgag acagtcattt tatatagcag
     2341 gagcggtcat tgttgtctca ggtttgtctg attatctaga cggggtcatt gctcggagat
     2401 ataatcaggt aacagactta gggaaggtgc ttgatccgtt tgcagataaa ttgacacaac
     2461 tttttctgat tttgtctatg gcatggtatc gaccgtggct ttggctgttg tttggtctat
     2521 tcttgataaa agaaggcttt atgtttgtag ctggattaat cgggctatct aaaaatatca
     2581 aattaagtgg agcgaagtgg tatggcaaag tagcgactgc tgtcatctat gttggcatga
     2641 tccttttgct gcttttccca gaattaccaa cgctgtgggt gagagtcatt tttgccgtca
     2701 tcacttacgg tcttttacaa tcttttgtct tgtatgctgt cgagtaccga aagatgtttc
     2761 aaagaaaata aaaaaggggt gtgacctatg tcgcattcct ttttttgata aatagactcc
     2821 cagtagctac ttctcgataa taagccaacc aaaccaaaaa caggagaagt tgtttttgaa
     2881 attatttctt gtgattcgga gttaaatggt aggctcacaa cctcttggta aacggtgttc
     2941 aatcagctga ccttcggtat tagctcaaaa aacggcaaaa tatgaggagc tattttcccg
     3001 tttttttctc taatacttag gtcaaaccgc tgatttcaca acctcttcct taaacggtgt
     3061 tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaatatgag aagctatttt
     3121 tgtttggctg ttcttattac ttgatgcagg acagcgtttt cacaaccttt gattcacggt
     3181 tttccagaag tagcttcttc gaaaaataag ccgaaatttc ttgaagctga tcacttctgt
     3241 cgcaacctct actgactaag gcttgatata agcataacct tgggattgca gttcaactaa
     3301 atcaaggaca cctgctggta caacgattac ttgttcaggt aaagaacttt ctgaaatatg
     3361 attagcacgc atagcattgg cgcaagcgtg aaaaacgact ccttgcaaat ctaagaattc
     3421 tgcattggca gagtctagat aaccggtaat cgcgatgcca tttacagata cgacaatcgt
     3481 cgtttctgga gaagctttta tcaggttttt tacgtttttc cctgtttctg accatttttc
     3541 taattcatca atatggaaaa cgactttcat tgaaatcatt cctttacttt ttaataatca
     3601 tcttgatcgc ttgttctagt ttagccgctt gttcttctgg attactatca ggtttctcaa
     3661 agcaattttt cagattatct gcaacgatca tgcccattac gcgatcaata ctagaacgaa
     3721 cagcgcttaa ttgagtgatg acatccatac attctttttc gtcttcgatc attttttgga
     3781 taccacgaat ttgtccctct gtacgtttca aacggttcag gatattttta ttatcaatct
     3841 ccataacaca ttctcctcta tttttataat tagataatac cccttatcgg tattttatgc
     3901 aaatataaaa agtagtgaaa aaaatgaaga gtcattctgg ttgacatatt aataaagctc
     3961 ctgtttaata taccccatga ggtatttata aaaatgtaaa tgaggtgcag aaaatgaatt
     4021 tgctatttca atcaataaaa tcgataacag tcccagaatt aaaggaaaag attttggaaa
     4081 atccagcgtt acttgatgtt agaacacctg cagaataccg gggcgggcat ataaaaggag
     4141 ctaaaaatgt tccattacaa agtataaaca gatatgatgg agacaaagaa aagaccgtct
     4201 atgtgatttg tcaatcaggg atgaggagta aacaagcagc taaagaatta aagaaatctg
     4261 gttatgatgt agtgaatgta cgtggtggca tgaatcaatg gtttgatcga acagtaggag
     4321 ggaaataaga tgaaaatcgt tattgtcgga ggtgtagcag gtggaatgtc tgctgctaca
     4381 cggcttcgcc gattaatgga agatgcagaa atcgttgttt ttgaaaaagg accgtatgtt
     4441 tcttttgcaa attgcggctt gccttattat ctttcgggag aaatcagtga acgggaaaat
     4501 cttcttgtcc aaacgccaga atcattatcc gctcgttttt gtttagatgt gcgtccaaat
     4561 catgaagtga cagccatctt tcccgaaaac aaaacggtag aagtcgtaca tgagggtcaa
     4621 aaacacattg aacagtacga tgcattggtt ttatctcctg gtgcaaaacc agttgttcca
     4681 tcgattccag ggataacaga agccgacaat gttttttcta ttagaaatgt accagatatc
     4741 gataaagtga tgcatgcatt agaaaaacag ccaaagcgtg ccgtgatcgt tggtgcagga
     4801 ttcatcggat tggaaatggc agaaaaccta aaaagaagag gtttagaagt catggtgatc
     4861 gaacaagcac cacatattct tccaacactg gatgaagaaa tggcagcttt tatagaaaaa
     4921 gaattgtctc atcaaggagt agaagtgatt acttctcatg ctgtcgctgg atttgaagac
     4981 cacgggaaac gattgcgact ggatgatggg cgtaccatcc ctgctgattt agttatttta
     5041 tccattggtg ttcgtcctga taaccagcta gcagtgaccg ctggaatcga attaggcata
     5101 cgcgggggta tcctagtaga cgaacgttat caaacgaata ttcctgatat ttatgcggtg
     5161 ggggatgcta tcgttgtaaa acagcaaatc actggaaaag atgcacttat ttctcttgct
     5221 tcaccagcca atcgtcaagg tagacaagtt gcggacacga tttccggaat ttctcgaaga
     5281 aatcaaggcg gtattggaac agcaattata cgaacgtttg gaatgactgc cgcatccacc
     5341 ggtttaagtg aaagaacagc caaagaaaac gaactgtctt ttgaagtcat tcatgtatca
     5401 ggaaaagatc atgcaagcta ttatccagaa gcaacagata ttttactgaa gttgatcttc
     5461 catccagaga ctggcgagat ttatggtgca caaggtgttg gggcaaaagg tgtggataaa
     5521 cggatcgata ttttagcaac agcaatcaaa gggcatttga cgatcttcga tttaccggaa
     5581 ttagaattga cgtatgcacc gccatttggc tcagccaaag atccagtaaa catgctagga
     5641 tatgcagcaa tgaacattgc agaagggctt agtgaaaccg tacaatggca tgaattgccg
     5701 acagaactag caaaaggaaa aattttatta gatgtgcgaa cagcagaaga attggaaaag
     5761 ggcaaattca aggaagccaa acatatccct ttgaatgaac ttcgggaccg attaaatgaa
     5821 ttagacagcc aacaagaata tatcgtcagc tgtcatagcg gattacgtag ctatctagcg
     5881 gaaagaatct tgaagcagtc tggctaccac gtaaaaaacc ttgatggtgc attttcttta
     5941 tatcaaactg tccgacctga agaactgata tatcctaaca aatgatactc gttaaaaagc
     6001 ttgcattcga ctcttaaaag aggtaaacta atcggttcca ccactttaaa aaaagaggag
     6061 aatgtgtatg gtcaacacac aaaaacagtt agaagaagca tatctgaaga acgtgtatca
     6121 aaagctaatt gataaaaaaa acgaactgcg ggaatcgatg gatacggcaa aaatagaagg
     6181 aaaccagtcg ttgaaagaaa tggctggcga gcttcgattg aattttgaca gttacttaga
     6241 taacctggat actttttcga tgattgaaat gaaaaataga gaaatcgatc agatgaatat
     6301 caaacagaaa aacgcagaaa atcagctagc aaagatcgaa cgtttattga aaagtcccta
     6361 ctttggaaaa gtcgttgtag actttctgga taatgagcca aaagaatcct tttatatcgg
     6421 tacagcaaat ttcacagatg atgcagatga aaatcttgtt tatgattggc gttcaccaat
     6481 tgccgaactt ttttacaata acatgattgg tccatcttct tatacggttc gtcaaaataa
     6541 aatcgatacg gttattaaag aaagacgaca atttcttttg gaaagagatc gtttggtcaa
     6601 gttttttgat acgtctgtag ctattcaaga tgacgtatta ttagaagtct taggccaaga
     6661 tgagaccaat gaaatgaagg ctatcactgc tacgatccaa tcggaacaaa acacaatcat
     6721 tcgggatgtg aaaagtcaaa atatcttggt aaatggcgta gcaggaagtg gtaaaacctc
     6781 tgctatcatg cagcgtattg cgtatctgct ctatttatat cgagatacga tgacatccga
     6841 tgacttgctg attctatcac ctaatcatcg gtttatcgac tatatttcga atgtcctacc
     6901 atcattaggt gaaagaaatc cactgaatct aaccatcata cagctggttt cacagctttc
     6961 agcagaggaa atagaaggtg aagaggctta tttcaaacgt atcacgggag aaaatgtatc
     7021 ggagcagaca gaacgtttgc gtagcaaaaa gtttatcgat aatctaaaac aatcagatcc
     7081 tttgttttta gatcatccga attttatccg tggacttact aaaaatggaa aaacagtcct
     7141 ttctaaaaaa acgatcgaaa aaatatatga gaaagttcct gctcatccta aattgatcga
     7201 taggcttcaa gcaacgaaaa aggcactgat gagcgaatgg aagaatcatc ttttgaaaca
     7261 agcaaaaagt cctgctgtgc agaatcaggt actctcgttg acagaagata ggcagttgga
     7321 attattcggt aaattgattt ctgatgattc ggaacaaagt attgtagctt atgcaaggaa
     7381 acttttacaa aaaaaatatc gaaaaataac cagacaaatc gaagaaatgg catgggtgga
     7441 tgagcatcag ttgtttgaaa gaatttatga aaaacgatat ggctcagctt atgcttggca
     7501 acccacacgt actgttgatg aagcagtcat tatattagct attcgtcatt tacttgttga
     7561 aaaggtaaat gtaccagcat ttcgctatct attgattgat gaagtacaag attataccct
     7621 ggcacaatta ggtctattga tcgaattatt tccaaaaact cactttactt tagtaggtga
     7681 cgagaatcag gcaatcttta attcttccac tacttttgct gatattatgc gttgtttcga
     7741 tgactaccat ctgccgatcc atcggtatga tcttagaaat agttaccgtt ctagcggagc
     7801 aatcacagag cttttcaaaa cctatgctgt ggatcaagag aagatcgaca tcgtatcgat
     7861 ccgaccgcaa ggaaaagaac ccgaataccg ctcttttcga tcctctgaag aattgttgaa
     7921 aatactagct gagattttgg tttctctaaa aggagaaaaa gcggcagtta tcacccaaac
     7981 agaagaggaa acccaaacgc tacaagaatc gattaaaaaa aattcatatg gattagaaaa
     8041 ctgccaaatc attcctttga gtctagcaaa aggactggaa tttgatcatg taatcttata
     8101 tccatttgaa aacgatggag atgagcaaag aagacgcaga caaatgtaca cggcgatatc
     8161 tagaggaatg aaaagcattg tcgtattgga aagagcaaca taattaagag ataaaaaata
     8221 aaaagaacaa ctgataaaaa gaacaaaata tttttcattt gctgatgaga aatgttttgt
     8281 tctttttctt aggaaaaatt taggaacact ttatgtgaaa agaaatgaaa tgtatggtaa
     8341 actcctacgt cgtaacaaaa aaacgtgagg tgaggatatg aaaaaagtaa caagagaaga
     8401 agttgcatca attttggtga aagataagta tttttcaaaa ggtaattact ggttaaagat
     8461 ttggcaaacg ttagtggctc ttttaggatg gatgatcgtt gttcttcctt ttatatgggt
     8521 ctttttccca ttaacgagac cagaaagagc caaggatttt tccttgtacg cttttttatc
     8581 agaaaagaaa atgctgtatt tcttaatcgg cttttttgta ttgatttttt tcagtttcct
     8641 gattacctca tttgtattga ctaggtggaa caatcgaaat ctatacaaaa aagtaaataa
     8701 atcttttgaa tacgccgttt gtataattaa gcgagacaaa
//
LOCUS       DAFEML010000081         8734 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFEML010000081
VERSION     DAFEML010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.083"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            2..74
                     /locus_tag="LP468_002364"
     tRNA            2..74
                     /locus_tag="LP468_002364"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="LP468_002365"
     tRNA            78..150
                     /locus_tag="LP468_002365"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="LP468_002366"
     tRNA            155..225
                     /locus_tag="LP468_002366"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="LP468_002367"
     tRNA            238..311
                     /locus_tag="LP468_002367"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="LP468_002368"
     tRNA            323..394
                     /locus_tag="LP468_002368"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="LP468_002369"
     CDS             660..1853
                     /locus_tag="LP468_002369"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL2081862.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="LP468_002370"
     CDS             1983..3455
                     /locus_tag="LP468_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2081863.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="LP468_002371"
     CDS             3538..4326
                     /locus_tag="LP468_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL2081864.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="LP468_002372"
     CDS             complement(4393..5061)
                     /locus_tag="LP468_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL2081865.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="LP468_002373"
     CDS             5176..6888
                     /locus_tag="LP468_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081866.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="LP468_002374"
     CDS             6891..8663
                     /locus_tag="LP468_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2081867.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2624 a         1487 c         1945 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaa
//
LOCUS       DAFEML010000082         8623 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFEML010000082
VERSION     DAFEML010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.084"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(152..1105)
                     /gene="menA"
                     /locus_tag="LP468_002375"
     CDS             complement(152..1105)
                     /gene="menA"
                     /locus_tag="LP468_002375"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL2081868.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1118..2221)
                     /locus_tag="LP468_002376"
     CDS             complement(1118..2221)
                     /locus_tag="LP468_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL2081869.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2311..3267)
                     /locus_tag="LP468_002377"
     CDS             complement(2311..3267)
                     /locus_tag="LP468_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL2081870.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3548..5482
                     /locus_tag="LP468_002378"
     CDS             3548..5482
                     /locus_tag="LP468_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2081871.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5939..6355
                     /locus_tag="LP468_002379"
     CDS             5939..6355
                     /locus_tag="LP468_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2081872.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6369..6935
                     /locus_tag="LP468_002380"
     CDS             6369..6935
                     /locus_tag="LP468_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL2081873.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6958..7944
                     /locus_tag="LP468_002381"
     CDS             6958..7944
                     /locus_tag="LP468_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2081874.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8099..>8623)
                     /gene="scm"
                     /locus_tag="LP468_002382"
     CDS             complement(8099..>8623)
                     /gene="scm"
                     /locus_tag="LP468_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL2081875.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2531 a         1665 c         1754 g         2673 t
ORIGIN      
        1 gcgacttttt cacaacctcc tgataaacgg tgttcaaaag cttgcatctg cggtaataag
       61 cccaaccaaa cgaaaaatat aaggagctat ttttatttgg ctgttcttat tacttgatgc
      121 agggcagttt tttcacaacc tcttcatgct gttaaatggc ttgcataatg attgttagta
      181 atagccccaa tacataactg gcattgaata agaccatatt tttgatggaa tagctgaaac
      241 tgataggctg gggtaacgtt tgcttgaatt gatccaaatg cttcttcaca attggcaagg
      301 tcaagaaggt gaccaagatc ggccattcat agataccgct caacaacccc attaaaatca
      361 cgaaatagca agcatacatc aatagctgga ataagactgt tcccgcagga cgtccgatat
      421 aaaaaactag tgtatagcga tgattttcaa tatcacggtc aagatcccgc aaattattag
      481 ccaacatgat attggcaatc gtaaacacca agggtaagga agctaatacg attgctgcta
      541 tagcccaaag atttcctacc aaagcaaatt gtccagatga aaagttgact gtcagatcat
      601 agacatctga accgaatgta ttgacataaa cgaccatggc aaaaattcca aggcccatag
      661 tcaccccact gaaaatttcc cctaaaggca ttcgagataa aggaatcggt ccgaatgtat
      721 agaatactcc aataaaacaa cagataaatc ccatcaaaag taaaagccaa cccgtattga
      781 tcgttagaat aacgccgata acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa
      841 tcaatacagg agatagattt ctgcggccaa tgacattttc ttcatactta tatacttcag
      901 aatgagcctt ttcataatcc atgtaattat tgatagcggt agtcgctaaa tcaaaaacta
      961 gcattccaat aaaaaataaa aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag
     1021 agaataatac ccctaccgca aaaggaaata cactagccac ctttgttcgt atttcaacta
     1081 cttctaaaaa gatttttagt gtcatggttc gtactcctta ttttagttca gaacggtcac
     1141 ccatcgtgta atgggagtcc tccgataatt tgaaggtgtc tttgattgga tcggtcacat
     1201 atactttatc gtcttttgtc acgaagatcg cttccgtccc gttattcaat tcgctttcga
     1261 cgtattccag tccttttttc acacccattg aaaagactgc tgtagacaac ccgtcaccat
     1321 caattgattt atctgttatg atcgtgacac ttgcgatatc attgtcgaac ggataacccg
     1381 tttttggatc aaacaaatga tggtattttt tgccatctac ttctaaataa cgctcgtaaa
     1441 ttccagaggt aactaatgtt ttgttccgtt ctttaataga acctaaaaca gatccgcgag
     1501 ccatgttcgg atcttggatg ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc
     1561 ctaagacata gacattaccg cccaagtcaa cgatggcagt ggtcactcct tgttttttca
     1621 agactttcac tacttcgtcc gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca
     1681 ttcctttttc ttttagataa acagtttttt ctttgtcatt tagttcgatc ttatgataat
     1741 ccactaattt caatgcctga tcgatttctt cttgggaagg ttttctggcg tcatcaaaac
     1801 cgattcgcca taattgtgtg attgcaccaa tcgccatatc gaatccgcct tgagaatctt
     1861 ggctatattc gtaggcccgc ttgactaacg tgtagacgtc atcagaaact tttactggtt
     1921 tgatcccagc ttgctcattc acttcatcga tctcagaacc tttttgattg atcgtgattt
     1981 tatcaccaag ttcttttact cgatcgaagg caggtttcaa tgctgattct ttgccttcat
     2041 catacacacg gatacgaacg taagtcccta acaagaactg ttcatcagaa tatggatctt
     2101 tcaatatctt ggtagctgct gaactttcag tggttgtttt atttgctgag ttgctgcagc
     2161 cagttagcac cataaaagag atgcccagtg tgattaagga aaatagtagt tttttccgca
     2221 tctttttcct ctcttcattt tgaaaggtga gacgactgcc taatctggct atcgtcccac
     2281 cctccaactt ttattagtat gattatgtga ttatttttct gttacgatat tatctacttc
     2341 gattgtttga gtgtcgcctt tttcagctgc attcactaat tgttgtgcgt acatgatgaa
     2401 tgaatgtgag ctgtgtgtag cacctgtaac aacttctaca ttagcaggtg agccatcttc
     2461 ttcgcccatt gctttgacga attcgtcgtt cagagtaggg atgtaagttt ttggttctgt
     2521 accgcttttt gctttcatat tttcattata ttctgtatca tcttgttttg atttaccgtc
     2581 tttgtcgata taatcaaagt ttgattcagt tactttgccg ccagcaactg tcatttcgaa
     2641 ttgcacacgg tagccgttag agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa
     2701 atcagcacca ttgtcgattt cgattgtatc tgtgttacca gcttgagcag cttggatcaa
     2761 ttgttgtgcg tagttttgga agctttcaga tgagtgagta gctccagtta cgacttccac
     2821 accgcttgcg ctttgtgctt ttaagaattg gtcattcaac tcaggaatgt atttttctgg
     2881 gtttgtgcca gattttgctt ccatgttttt gttgtattct gcatcttttg tttttgattc
     2941 gccgttttca ttgacgttat catattttga ttcagtgatt ttgccgtctt ttacaaccat
     3001 ttcaaagact gcacggtaac catttgaata atttttttct tctaatttat atgtgccgtc
     3061 ttgcaaatct ccgccagcta caacttttgc agatgattct gttgtgcttt ttgcagtcga
     3121 agattgtgct gtagatgatt cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca
     3181 agcgcctaac actagagctg aaaatgctaa tacggcaaat ccagttacaa aacgtttttt
     3241 cttcatttta ataccccacc attccatttc tagtccacaa tttttctttg tgattcatta
     3301 tacattctaa tctttttagc ctataagtca actatttttg ataaataacc catgtaatat
     3361 ttcaaacgtt ttctttcagc aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa
     3421 aatccaaaag gagttagaca aaagaacaga acatctatat aatatatgga gattgtgtaa
     3481 taagtatcaa actaaaagaa ttatcatata ttcattatat agatagtcta taaggagcgg
     3541 atgatcaatg gcaaagcaaa atattgtcgt tgtaggagca ggatatgccg gtgtttcagc
     3601 tacaaaatac ttggcaaaga aactgaaaaa agaagatgta gcaattactc tgatcgatcg
     3661 tcattcgtac catactatga tgaccgagtt gcatgaagta gctggcggac gtgtagaacc
     3721 agaagcaatc caatacgatc tgcagcattt gtttgctcgt caaaagaatg tacaacttgt
     3781 cacagacact gtaatcggta tcgataaaga acgaaaaatc gtcaagacca aattaggttc
     3841 ctatcctttt gatcagctga tccttggaat gggcggagag ccgaatgact ttggtacacc
     3901 tggtgtcaaa gcacacggat tcaccctttg gtcatttgaa gattctgtaa ggattcggga
     3961 acatattgag aagacagtag caaaagctgc attggaacca gatgatgaac tgcgtaaagc
     4021 catgctgact ttcgttgtct gtggttctgg atttaccggt attgaaatga ttggggaact
     4081 gatcgactgg aaaaatcgcc tagccaaaga ttataaatta gatccaaacg aaatcacact
     4141 gatggtcgta gaggcaatgc cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa
     4201 agctgaacgc tatttgcgta agcacaacgt ggaattatta ttgaatgcac caatcgtaga
     4261 agtggctgct gatcatatca aattgaaaga cggacgcaac attccgactc acacactgat
     4321 ttggacagct ggtgtcaaag gaacttctga cgctgctgac tttggattag aatcagcacg
     4381 cggacagcgg ttgatcgcca atgaatatat gcaggcaaaa ggctacgaag ataaaaacat
     4441 ctatatcatt ggtgatttag tcttttatga agaattccca ggaacaccga caccgcagat
     4501 cgttcaagct gctgaacaaa caggacacac agccgcagcg aatatcgtgg cttcgatcaa
     4561 aggcggagaa aagcataaat ttaaaggaaa ctatcaagga tttatggttt ctattggtgc
     4621 caaatggggg gtagctaacc tatttgataa gatccattta agcggatttt tagctatcgt
     4681 aatgaaacat atcgtgaatt tgaaatactt ctttgatatt cgttctggtt attatatgtt
     4741 ccaatattta atgcatgagt ttttccatat caaagatgat cgcaacgtga ctcgaggaca
     4801 ttcttctcgt tacggcaatg tcttatggag tgtgccactt cgtattttct atggtttagt
     4861 ttggttcgtt gaagcttcca aaaaaatcat tgggaatggt gaagtgttca aaccaagtac
     4921 ttggtttggt gaaggatcat ggttcactgg aaacagtgtg ttcccttgga catgggaata
     4981 caatgtaaca gatgttgcca gtggtgcttc tgctgctggt gatgcaacca cagctgccag
     5041 cggagcaggg gcaagtgccg gagaagcagc gactcaagct gcacattttg gtttgagtta
     5101 tgcatacggt gaagaaccaa tggctgtgat tgagaagtca ccagactggt tcacaaagat
     5161 catgcaagtg atcatgccaa acaatgatgt agcaatgttc ttccaaaaat tcatggtatt
     5221 ctttgaaatt gccttggcat tagcattgat tgctggatta ttcacatggc tatgcagtgc
     5281 gacaacgatt gtattggtga tcacgttctg cttatcaggc atgttttact gggtaaacat
     5341 ttggttcatt tttgttgctt tcgcattgat gaacggttcc ggacgtgcga ttgggttgga
     5401 tcgctgggta attccatggc tacaacgtac actaggtaat tggtggtacg gtagaccaag
     5461 ttcccagtac ggcaagaaat aaatagataa agaacgttat ttgaatgcaa gatttcaata
     5521 gaaaggggct gagacaaacc gtcacagcct cctttttatg taaaattaaa ggaataagat
     5581 gcccgagata agcctccatg agcaagacac aggtgtcaca acctctgtta caacctcttg
     5641 ttataaacgg tgttccagaa gtagcttctt cgaaaaataa gccgaaattt cacaaaaact
     5701 tgaaaagtaa ttttcgtaaa ttccttctta tttcttgaag ttgcccactt ctgtcacaac
     5761 ctcttgttat aaacggtgtt ccacctgctg cttctcggta ataagcccaa agaattagaa
     5821 aacatggaaa gctgttttct attcttcgtt cttattactc aaagcaagac acaggtgtca
     5881 caacctcttg tttttatgct aaaattgggt gagttaatct ggaaaaagga gaacaaaaat
     5941 gagccttaaa gaatttgctg aaaaaagtct gctcaaacct tgggatgttt ttattatttt
     6001 gcttttgact gttctttctt ttttaccagt catgattttt ggtcttcagc aaaacaccgc
     6061 aacagcagaa aaagaagcgg tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt
     6121 gatggctgga gaagagagca acacatatac ttacaaagat gaacacggag attataactt
     6181 gatcgagata gatggcgatc gagtacggat aaaagaagca gattgcgatg accagatctg
     6241 cgtacgtcga ggctgggcaa cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt
     6301 agtgatcgaa gtccgttcaa cagatggagg tgacgaagac agtctgattt attagacctt
     6361 cacacaccat gagtaaatta caaaaaatga tttatatttc gctacttgtt gcacaaggag
     6421 tgatcattgg tttattggaa aatatgatcc cttatccttt ttcttttgcg cctggtgcaa
     6481 aactaggctt agccaatcta atcacgatcg ttgccatttt taccatgaaa aaacgagaca
     6541 gcttcttact actttggcta cgactattcc tgactacttt gctaggcgga acgatttcca
     6601 cattccttta tagtatgagt ggtgctttgc ttagttattt tggaatgtta ttggtcaagc
     6661 aattaggacc aaaacgtgtc agtatcatcg gaattagtgc ggccggcggt ttcatgcata
     6721 atgtcggaca gcttttgatg gcttctttca ttgcacaatc atggacagtc atgttgtact
     6781 tgccagtcct ttcagtttta gggattttat cagggattgc aatcgggatc gcagcgaatt
     6841 atcttttacg acatgtgcag acacttcaac gattccaaaa agattatgag cagggaacca
     6901 aacaaaaatg gagcccaatg tttaccaaaa aataatcgtc acacaaggag tttttttatg
     6961 aagctacatc caatgtggga aaactatcct gctttaagta aagaattgac agaaacacta
     7021 aaacggatgg aagaaactgt ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa
     7081 acgatccatg ccggcggaaa gctgttgcgt cctgcctatc agctattgtt ctcacaattt
     7141 ggaccagagc aagatcgaga caaagccatc gctttggcag cttctatcga aatgctccat
     7201 acggccacac tgatccatga tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct
     7261 aatatccgta gtcagtttgg taatgtcgtt tctgtctatg caggagacta tttatttgtc
     7321 tgctgtttta aactattgtc tgattactcc acttccttga aaagtctcca attgaattct
     7381 cgcagtatgg aaaaagtatt gaatggcgaa ttagggcaga tggatgatcg ctataattat
     7441 gaactttctg taaaagaata tttggaaaat atttcaggta agacagctga actgttccaa
     7501 ttaagttgtt ctgttggcgc ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca
     7561 ggagatatcg gactttctat cgggatggcc tttcagatta tcgatgatat tttagattat
     7621 acaaaagaga gccaggaaat cggcaaacct gtactagaag acatgcgtca aggggtctat
     7681 tctttaccgt tgatctactc tttgcaaaaa aacaaaccaa agctactacc ttatttagag
     7741 aagaaagcgg caatgacaga agaagatgtc gacgccgtac gcaaaatcgt tgaacataca
     7801 ggaggcgtgg aagaagctag gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa
     7861 ataaagaaat tacctgccac ctctcttcga acaaaagaga atctcttttc ccttacccaa
     7921 ctgattttgg atcgcaaaga ctgaataggg aaaggttcga tacgtaaata aatttctcag
     7981 aaggaaatct acgtgttttt tgacaaattg aattgtagtt cttgtattta tgataaaaag
     8041 caaaaataaa gagcaacgtc cgttagcgac gttgctcttt tttatcttga atattttttt
     8101 accttttcga tttcttataa ctcataaaag tgattcttaa accgattaca agtaatataa
     8161 cgcctgcgag tgttatccaa ttattcgatt gacttccagt tttaggaagt gctctttttg
     8221 atttgtttcc attgtcattg cttgttttat tagttaagtt aaagttcgtc ctgttatccg
     8281 aacttgtttt tgagaaggag acacttgcat gacgtgtatc gcttgtggta gacgacgtgt
     8341 ctgtactatc gcttgaagtt gatgaatctg agctatcact tgtggtagag gatgtatctg
     8401 tactgtcact tgaagctgac gtgtccgtgc tatcacttgt agtggtagat gaatctgagc
     8461 tatcacttgt ggtagaggta gtatctgtac tgtcacttga agctgacgtg tccgtgctat
     8521 cacttgttgt ggtagatgta tccgtactgt cgcttgaagc tgacgtgtcc gtgctatcac
     8581 ttgtggtaga ggtagtatct gtactgtcac ttgaagctga tgt
//
LOCUS       DAFEML010000083         8578 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFEML010000083
VERSION     DAFEML010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.085"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(315..845)
                     /locus_tag="LP468_002383"
     CDS             complement(315..845)
                     /locus_tag="LP468_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2081876.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1027..1683)
                     /locus_tag="LP468_002384"
     CDS             complement(1027..1683)
                     /locus_tag="LP468_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL2081877.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1810..2283)
                     /gene="dfrF"
                     /locus_tag="LP468_002385"
     CDS             complement(1810..2283)
                     /gene="dfrF"
                     /locus_tag="LP468_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL2081878.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2702..2920)
                     /locus_tag="LP468_002386"
                     /pseudo
     CDS             complement(2702..2920)
                     /locus_tag="LP468_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2951..4164)
                     /locus_tag="LP468_002387"
                     /pseudo
     CDS             complement(2951..4164)
                     /locus_tag="LP468_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            complement(4505..4747)
                     /locus_tag="LP468_002388"
     CDS             complement(4505..4747)
                     /locus_tag="LP468_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2081879.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4779..5336)
                     /locus_tag="LP468_002389"
     CDS             complement(4779..5336)
                     /locus_tag="LP468_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2081880.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5349..5537)
                     /locus_tag="LP468_002390"
     CDS             complement(5349..5537)
                     /locus_tag="LP468_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2081881.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5550..6116)
                     /gene="amaP"
                     /locus_tag="LP468_002391"
     CDS             complement(5550..6116)
                     /gene="amaP"
                     /locus_tag="LP468_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2081882.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            6533..6706
                     /locus_tag="LP468_002392"
     CDS             6533..6706
                     /locus_tag="LP468_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081883.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            7346..7819
                     /locus_tag="LP468_002393"
     CDS             7346..7819
                     /locus_tag="LP468_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL2081884.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            7828..8055
                     /locus_tag="LP468_002394"
     CDS             7828..8055
                     /locus_tag="LP468_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081885.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         2608 a         1683 c         1274 g         3013 t
ORIGIN      
        1 ttattttttg aaatcaactg tctttctcat atttactatt caattttcat agtgatatag
       61 gtacaattta tatcactact gtaaaaatgg ggttttgcct tataaataca gcgttttccg
      121 cttgttagtg tatagtgttt cttgtttttt gtgcccccct tgttagataa cgggggcttt
      181 gaacggctcg caagctcgcc gaaccgccga agcgaaccgc ccccttgcaa gcatggcgga
      241 aaaatcttaa ggattttccc gccaacgtgg tcggatcgct ccgtcggttt aacagctttt
      301 ctgtttctct ctagttatct acgcatataa atcaaatcgg ttattccgtt ataagtctgt
      361 gttttacaaa gccttaactt tatttccctg tctatgttgc ccaaaagacg aaccccattt
      421 cctaacagag taggaataac agaaatgtaa tatttatcaa tcatattttt gcttaccaac
      481 tgctgaacaa gatttgctcc gccacaaatc caaatatcct ttcctgcttc ttgttttagc
      541 cgttccaata ataaaacagg attttcactt gtaaaatgaa tttgttggga agaattgcac
      601 tctttatgtg ttaatacata agttgtaaat ttattatata cccattcttg cggagaaagt
      661 tcagtaacaa cctgatgaga agtattccac cccattaaga cagtatctat atctttggta
      721 aattctgtat aagtgtcgat gttttcattg tcatttccat gaccatttag ccaagctact
      781 ccaccattac cgtccgcaat atatccgtca aggctcatgg caataaataa aactactttt
      841 ctcatttttt ctcttttata aatacaaaca ggaatttatt tctctttttt actcataagg
      901 gaacaactga ttgctacaaa taaacccatt aaaatccatg gaaatgctgc tcttataaaa
      961 tcactaacca tactttattc ctccttaaat tccaatttcc ttagttctac aaactgaaat
     1021 ttttgcctat gaatgtatct tgttctttat acgcaaacag gcttctgtgt gcataatcca
     1081 atgtcttgaa aacggcattt gaattagtcc acaaatatct ttattacacc aataatcaat
     1141 cagccaaatt gctttttcat tgtcgtttac tacattcaac gattctaagt atccttttct
     1201 ttctttcggt atttttcttt tcaattcatc ataagataac cgttcaagca ttttctcagt
     1261 gctttcccat acttcgaaaa tatataaata taattcttcc agattaagct gttttgaaaa
     1321 gtctgcaatc tgctgtttca tgagttcatt tcctgttgta atgataggtg aattgatacg
     1381 ctcttgataa ttgcctgcaa aaaatacttg ttcatcttca tttatcactg tatgcacaac
     1441 tatatcttca atgcggaaaa tatgccaaat agaataagca atcgtcttac tatgataacc
     1501 atcagcgttt atgaagggga ttgagttaaa atcttctctg cataattctt ctttgaaaga
     1561 tactaaggtt tgtattaact gacttcgtaa agtaagtaaa gtatcaatac ccctcttata
     1621 agtatctttc ttttttattt gtgcctgcat tgttttatta agttcagacc attccttatt
     1681 catattcaat cctctctcaa attctgattt tatcgcccca tacaaactgg aatttgtctt
     1741 acaacaattt atatatgcat aaaaagcaat atatttatga aaacacccta aatccaaaat
     1801 ttactcaatt cattttttcc ttacataaaa tgttctcgta tatttcactt cctcaccaag
     1861 tgtttcccct atcaaaactt caaaatcatt gatatcaaat tctggaaaga atgtatctcc
     1921 atcttcaata tttaaatcta cttctgtgat atacatttta tctactattt gcaaagcttc
     1981 cttaaatagt ccatatccac cagatatgta tacatctcgt cctttagcca ataataatgc
     2041 atcttctaat gatttaactg aaactaaatt atctccttga tactctgttg tggtggaaac
     2101 aacaatattc attctattag gcaacggatg accgatttct tcataagact ttcgccccat
     2161 aataaccaca ttacccgttg ttaactctct aaattgcttt tgttctccct ttattttcca
     2221 tggtatatta ccattcttgc ctataacatt attctttgac ctcgcaacaa tcaaacctat
     2281 catctatttc atcctccata atatgatgtc gtacctgtga ttccatcaag tgcaccacat
     2341 cttaacaaac tcaaaattat ctcgaactaa ccagctcgac aaattccttt tttgtcttca
     2401 tctgcattat atcatattgt tataagcatt gccatttctt ttctgctttt gaaaagttac
     2461 ttatcagcct atgttttgta aagggtgata ttcagcattt ctcacgcaac aagcccttga
     2521 caaaccatag actaataagt tttaaggtaa tcaagcagaa atgaaatagt ctgctgtttc
     2581 acggcaacaa aaaagagata ccaacacact tatgtagtat ctcttagtct agtagcaata
     2641 ttcttttgtt tgcaagcagg taaacatggg ctgtttctta atatcttttt gtttgggaaa
     2701 cacctttttc ccatcctttc accgttgcca tctctgctgc gcacaatgcc acagggataa
     2761 accatagcaa accgcctaat aacaagaaaa atactaagct gaagcctgag gtcgcgaatg
     2821 tgggatattc atataatgaa acgaccattg agatggtcat agccaaaaag ccaaagaacg
     2881 ttaatttttt tgcaggaatt ttcgttttgc tttgttgcat gaatcttcct cttttctatt
     2941 tgaatttgtt tcaattgagt ttgttgccaa agaagaaaaa gtccaatcct tcttcttgtt
     3001 cttcttttgt agtagtgatc gttgtaaagt gcatcgccga ttttaaaatc actgttgtca
     3061 gcacataggc atacacggca gtaatgatga caccaatcac ttgaatccct aagaagtacc
     3121 agctgcttgg attcgttagt aaatggctgt tagatgcaaa gatccctatc agaatcgtac
     3181 ctgtgaatcc gcccatgcca tgaacacccc acacatcaag tgcatcatcc cattgtttct
     3241 ttttacgaaa atcaacagca gcatgacaga cgatacccgc aatgatccca atcagcatgg
     3301 cactttttgc ttctacataa ccggcacaag gcgtaatggc tgccaatcca gcaacggatc
     3361 ctgttagtac gtcgacaaaa tcaaagccat ttccttttac ttttgcaatg atcagccaag
     3421 taatcatcgc aaatgcaaga gcgatgaatg ttgaaccaaa tgcattgact gcttgttcat
     3481 ctgctcgaag tgcaccaccg gaattaaaac cgaaccagcc aaaccaaagc agtcctgtac
     3541 cgatagcagc tgccataaga ctgctatgct gacttctttc tcctaaagga atctttcttt
     3601 gaccaagtgt gaggatacat gctaaagagc cgaatccagc tgtcgtgtgg atgactgctc
     3661 caccagcgaa atctctaaat cccatctgat ccaaaaatcc gccaccccat atccagtggc
     3721 aaacagggaa ataaatcagc agattccaaa aaataacaag tataatatag ccttttaaat
     3781 tcaatctccc tgcaaaagct cctgtcatca aaggaacggt aatcacgata aacatcagtt
     3841 ggtaaagaaa gaacattaaa aatggaatcg ttgcaccatg aaacatgttg gggaagcttg
     3901 taacatgtct catcaaaaag aaatctgccg ggtttccaat aacaccgccg atatcccgtc
     3961 caaaggccaa tccgaatcca ccaaataccc acataatcgt tgttatccca acggagagaa
     4021 aagattgaga catgatcgtt agtatattat tcttccgtgc taatccgcgt aaaaaaaagc
     4081 tagaccagga gtcatcaggc aaaccattgc tgtacataaa atcatgaatg ctgtatctcc
     4141 tgtattgata ggtaatgtat tcattttttt cgcctccttt ctacgattac gagtataaaa
     4201 gaaggtgtag ttgttttttt cttctgtttt tttgaattaa tacttgcatt tataaaagac
     4261 agacaattaa taaaagcttg atgtgttgtg ctctttttcg tttttcacac aaataaagac
     4321 aaaaaataaa cggtcttctt tttatagaaa accgtttatt ttcgtctttt tttattttta
     4381 aagatatttt ttcataagga ataaagaata cttcatataa aatatataaa aaagaaccgc
     4441 agcgagtgtc gctacggttc tcaaatttgt tcttcatttc aacataagtt tttcttcaat
     4501 ttgcttataa tttacgtgca aagaatgaaa cgactaatac taaaatgatt gcaccgatca
     4561 atgatggaat gatagccatt cctgcaattg ttggtcccca agttcctagt aaagcttgtc
     4621 caattgctga acctactaaa ccagcaatga tgtttgcgat gatccccatt gatgatcctt
     4681 tattcgtgat tgctcctgca attgctccaa tgataccgcc gacgattaat gcccaaataa
     4741 atcccatttt aaattcctcc taactgactt cttacttctt attgtacacg tggttcgtta
     4801 ttttctttga ctttttgtgc acctttgcct acagcagatt ttgctttatc tgtttggcgt
     4861 gaagcaaatt gtcctgtgga ttttgctgct tctgttactt tgtcttgtac tgtttcttga
     4921 tctttttggt attcttcttg tgttttgatg tctgcaacat tcacattcac ttcgataaca
     4981 tctaaatgtg tcatattgtt tacttcagta ctgatcaatt ctttgatttg gttgtaaata
     5041 tcttcgatgt ctttaccgta ttctacgatc acatctagat ccacagctac ttgtttctta
     5101 cctacttctg tattgatacc tgctgttacg ttatctgtgt tgactaattt ttcagccata
     5161 tttgagaaaa atccgccatc taatgtcaat agaccatcta catctttcaa tgcataaccg
     5221 atgatttttt ggatgacttt gtcttcataa gtcaattcac cattcatcat gcggttttct
     5281 cctttttcat ttgccaaaac tgatccattt gttgtattca tgtttttgtt ttccatcttt
     5341 gtttcctcct atgatttaaa aaattgatca actattcctg actgtttcaa ataaaaaccg
     5401 attcctgcgc caattgctgt catgattatg atcaacaatg tcttgaaaaa tccaatcgtt
     5461 aaccataaaa cagctagcag tagtccaaga cccccaaaga taatagggag cttgtatgct
     5521 gaaaatagtt ctttcattat ttggccctcc tattccactc gagagtgctt gtagtctctt
     5581 gtatcttctt gttcttcata accgctgtat gtgactgcca ctttgaccgt ttcttttgtt
     5641 ccgagtactt tagttacttc ttcttcgata tcttgcatca atacacctgt tttccctact
     5701 aatgaagaag ttcgtttcaa gtctccgttg acatggatat ggattcgatt tttcgttgaa
     5761 cgtatccgta ctttaggtga atgaatgaac tcttcttcgt gtaaatggga acgtaccaac
     5821 ccttcgatcg cttttttgtc gattgttagt ttgccatctt cccgtttcat aacgaaagtt
     5881 cctcttgact ttggatagaa aagaacgact agcaagatga taatagcaag aacggcaaat
     5941 actacagctg cccagaaaat atattgttgc atgtagtaat tcgttaaagt aaagaagcga
     6001 aatcgttcca attgttcagg cataatatac ggcgcattga tcaacgcaat cgctagaaat
     6061 actgaaagta gcagtaaact catgataaca ccgattattt ttaacccctt attcattttc
     6121 cacctcctat aaacttattt ttaccctgta aataactcta ccgacaatca cagtatagat
     6181 agcgaacagt tagcatagca tcagtaaata aagcgctacc aaacattgct ggatcataac
     6241 ggcgttttat tgccagtctg atactgaaat aacaattgct tacttattct ctatttactt
     6301 ttgattgctg gctatactta aaggatatta ttcaagatta aaaattgcaa agattatgct
     6361 cagttattat tacaagattc tatttattta ttaaattttt tcggagaatt aaaaaataca
     6421 ataaataact ttagttactt taatgcgttc ttactttatt tttatattat catttttctt
     6481 attcacttct ttggtttata ctattcttat aaataaaaac gaggtatgtc ctatgatgaa
     6541 aagattgtac tattcattga tcataacgat tggctatttg attgtatcaa atctaggaaa
     6601 tatggtattt ggtatcagta aagaattcag ttggactact acattatggg aatctctatt
     6661 ctttttcatc ttcgtatttt tgttacaaaa ttatcgaaaa aaataaacat gtgccatcta
     6721 tctgttggca catgttttag gatttatggt actttttatt cggcaatcca ttttattttt
     6781 ctacttcttc ttaatacctc taacactttt gatttataaa ctaatccaat gcatctactt
     6841 gcgcttatta agctatttca gctagatagt accaccccat gcgtcaatgc ttgattttcc
     6901 ttttgtataa cattgtataa gcaataaagg acaaataagt ggtgattaca ccaaaccatt
     6961 gaataagaaa aattctgata cgtaaataaa catgaacttg aaaaaattaa tgaatcggtt
     7021 agctactacg tagttgtctt ttttctcata cagttctgtt aacttacact tctcttcgct
     7081 agataataaa aaatcctcca actgtattgt ccaatataat cccaggcatc taaactagca
     7141 ttatagaaga gacacacata gaatctaaaa taactggttt taaatgtttc ttacaatcaa
     7201 aaaaagctgt taaatgcact ccacaccttc atactctatc attttttata aacgatatat
     7261 ttttattgtt tttcgataaa aaatagttgt tttacaataa ttattctgct atattttagc
     7321 tatcaaagat aaaagaggga taaaaatgaa atttaaaaca ttgctattaa aatttgtcgt
     7381 tttaggtata agtgccgtat ttattttgtt cggcgtactt ttttatactc agatcgctac
     7441 aagcgaaaaa ggattcaatt ttgattggca gaccacatta tttgtttctg tcatttactt
     7501 tgcccttctc ctagggatcg ttattgctta tttcttattg aaactattga aaaaaatcga
     7561 agataaccaa gctttttcca ctcaaagctt aaacatacta aaaaaaatcg aacgaaccat
     7621 tttgtttatt ggtttcgcct tttttggctt acttcctaaa tttatgaaag tagcggattt
     7681 agacgatgct ccaggtttga tgttggtagg aatcgctgtc gtattcattc cttttgcagt
     7741 atacacatta acaagcgtgc tggaaaaact gcttgaacat gcgattttac ttaagacaga
     7801 tcatgatttg acagtgtgag gtgcgacatg gcaattatcg ttaatttaga tgtagtatta
     7861 gctcaaaaaa aaatgagtgt gactgaattg agtgagaaag tgggcattac gatggcaaac
     7921 atctctattc taaaaaatgg aaaagcaaaa gccatccgtt tttccactct cgaaaaaatc
     7981 tgccaagttt tggagtgtca accaggtgat ttgttgacct ataaaaatga ctcgaatact
     8041 ataccagaag aataaaataa agtagaacaa acagtaaata aaaaataatc tgaatgatag
     8101 atgtgtgaga cttttagaag ttatttacgt ctattattca gattttttat ttcgattgaa
     8161 taccgtttta tctataaata agatatgtac tgactcatac aaagggggcc ttttcttctc
     8221 catgtactat cacttttcct gatacaactg gtttcctgtt acgttgtagt tggatctgct
     8281 tttagtataa tactttattc attccaccag actgatagca gtttgagcag tctaaataat
     8341 catgtagtat tacaggccat tctgtttcat accttgaagt gcttaaaact tcagctaatg
     8401 gcccattgtg ttaactctta ctccattctt ttttagtaag ctcccatata tactgtaaag
     8461 ccttctatat attatgtcat gttgcttttt aacatttact atgtagtttt gataaaatga
     8521 tttgaataac agtgatggac aattcttttt tatttttaac attattttga taataatg
//
LOCUS       DAFEML010000084         8570 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFEML010000084
VERSION     DAFEML010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.086"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..686)
                     /locus_tag="LP468_002395"
     CDS             complement(<1..686)
                     /locus_tag="LP468_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081886.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQ"
     gene            complement(876..1466)
                     /locus_tag="LP468_002396"
     CDS             complement(876..1466)
                     /locus_tag="LP468_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL2081887.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            1950..2177
                     /locus_tag="LP468_002397"
     CDS             1950..2177
                     /locus_tag="LP468_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL2081888.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            2193..3359
                     /locus_tag="LP468_002398"
     CDS             2193..3359
                     /locus_tag="LP468_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL2081889.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            3593..4636
                     /gene="hrcA"
                     /locus_tag="LP468_002399"
     CDS             3593..4636
                     /gene="hrcA"
                     /locus_tag="LP468_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL2081890.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            4730..5293
                     /gene="grpE"
                     /locus_tag="LP468_002400"
     CDS             4730..5293
                     /gene="grpE"
                     /locus_tag="LP468_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL2081891.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            5344..7173
                     /gene="dnaK"
                     /locus_tag="LP468_002401"
     CDS             5344..7173
                     /gene="dnaK"
                     /locus_tag="LP468_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL2081892.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            7324..8490
                     /gene="dnaJ"
                     /locus_tag="LP468_002402"
     CDS             7324..8490
                     /gene="dnaJ"
                     /locus_tag="LP468_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL2081893.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
BASE COUNT         2901 a         1477 c         1835 g         2357 t
ORIGIN      
        1 aactgtttca cgtcattggg atttcctgta ggaatagcta ctacagatgc attatcaatg
       61 atttcttgag ttgtttctct aatgaacgct ggataagatg tttgatctgc aggcatttgc
      121 caatgtgaag gaactggata actagtgatt gtcccgtcat ggttacttga atacactaaa
      181 actccctggt aactgtattt cccagtgagc ataaccacat ctttcggata gactgcactc
      241 cctgcatcat aaggggcgat aggtgttcct gcaggataat gaataacatg taattcgaaa
      301 tcacccgatg tatctctaaa agtattacct ctaatagcta gccaaacacg tgcgtactca
      361 atttgtagat cagaatatcc tgctaacgga tctattgact gagaagactg tgaggaggtt
      421 gtgtctattg ttgaagaaga aatatttgtc tcaactgtac tactagatgt agaagaagta
      481 ttgggctctg agactttact gcttgttgaa gatgtattcg tttcagtaga agctgatttc
      541 tgagtacttg atttttcagc tgaactggtt tgtctgattg aacttttgtc tgtggtcgca
      601 gatggatcac tattttcttt actaggagac gtacatccta caaggaataa agagaccaac
      661 aataaaataa aacctaactt tttcatataa aatacctcat tattttttta ataccagtat
      721 agcataatcc tgaatttttg aatccgtaaa accttgtcta tgaatataaa tagagtgtat
      781 cttctttgat aaatgtcaga aaaagtgtga caaataatca tcagtaaaat tacttgtcac
      841 actattgata aggagtattt aattgaagag aatgattagg agaaaggatc tccgtacttt
      901 ttatagtaat catagaatcc aagtttgtat agacgaatcg ttttttctct tatttcttct
      961 gtttcaaaat ggactgcttg aagaatcaag tctgtgaatt ctataggagc tgttccattc
     1021 gcagtaatca aattacgatc tttcacagct tgttgttcta taaaatcttc tttattctga
     1081 taattttccg attctaacca aggaaattgc gcatttccgg tgtgtttgta accttgcaat
     1141 aatccgctct gagctaaata atcaactgcc ccacaaatag cagctactgg tacgtctgtt
     1201 tttaacaatt tatcgattat ttgatataaa tgatgatttt ttatgtccca tgaattgcca
     1261 ccgatcataa taaaaaggtc aactttttca ggtatttgtt cgattaagta atcgattttt
     1321 gtttttaatc ctccaatgga agtgacctct gattggatag aagcagtttt gttttgccat
     1381 ttctcatttt ggtttagtgt gctagtaata taagcacctt cccaatcggc atattcctct
     1441 aatagaaacg taatcgcagt tttcattttc aagctctcct ttactatcta taacaaggac
     1501 aacagtttta acctacagac attcattaaa attgggtagc gacagcgaaa acaacaattc
     1561 ttaagtttta gacagagtat acagatagtc aacttaatta aatacgaact aaataaaaat
     1621 gacaggtaat catttttgtt taccagcatt ataacatttt gcatacatgg atgacaaaag
     1681 aaccaattcc cacttgcttg agtacaatat taaaagaaac tggaaggcaa aaagtaatta
     1741 tagaaacgaa aaataaatca tatcgggcac tcagacatga aaacaaccct agagatatat
     1801 aactaggtaa ccagtttaat gaaagaaaaa atcatccaag aagtcgattc ttggattttt
     1861 tagtggattt gttcgccaaa tacgtttagt atgcgtatat gagaggttgt aagcaaagcg
     1921 ttgtggtctg agcacttaag gaggaatctg tgaaaatagc ttttcatatt tttgcagatt
     1981 ttgacttaat gccgaaggtc agctttgcga ttaccgttta tcgagaggct gtaaaagcac
     2041 cgtgtagctc cgatgacaat aagcaagcat ttttagagct aggtttcctt gattctaaat
     2101 atgcggctta tttcaatgag ttggtgcttg aacgcgattt taagaaggtc gaaaacaggc
     2161 acgacttttc gacgtaagga gaaagaattt caatgataga aacaataaat cccgcagaaa
     2221 acaaggtttc tgcgtacatt catatcccat tttgcgagca tatctgctat tactgtgatt
     2281 ttaataaagt ttttttagaa gggcagccag tagatgagta tgtggaaatg ctgctgaatg
     2341 aaatgaaaat aatgctagaa agtcatccga cagcgaattt agaaacactt tacgtagggg
     2401 gcgggacacc aacttcttta tctgctaaac aacttgatcg actgttatca ggtgctagag
     2461 agatcctgcc ttttcaaaat ggtaatgagt ttactgtaga agcgaatcca ggtgatttga
     2521 cccgtgaaaa acttcaagta atgaaaaact atggcgtcaa tcgtttatcc atgggagtgc
     2581 agacatttga taatcgctta ttgaaaaaaa ttggacgtaa acacaccgca gaagatgtgt
     2641 atcaaactat gcaattttta gaagcagaaa attttaccaa tgtaagcatc gatttgattt
     2701 atgcattacc gggacaaaca ctagaaggat atctggatac tttggaaaaa gctttggctt
     2761 tggatctgcc tcactattct ttgtactcat tgatcctcga aaacaaaaca atgttcatga
     2821 actgggtacg acaaggaaga ctcgaactgc ctgatcagga aacggaaacc agaatgtttg
     2881 aagagacgat tgaagcaatg gaaaagcatg gacgtcacca atatgaaata agtaactttg
     2941 ggctctccgg acatgaatct caacataacc tcatgtactg gaacaatgac cactattttg
     3001 ggtttggagc tggtgctagc ggttatcttg gagatattcg ttaccgcaac aaaggaccaa
     3061 tccaacacta tttacgccca ttacgagcaa atgaacgccc ggtattggaa gaagaaaaat
     3121 tgacacgaaa aaatcaaata gaagaagaaa tgttcttagg actaagaaaa aaaacaggga
     3181 ttactaaaaa acatttctat gatcgctatc aaaaaacaat tgaatcggtg tacggtgatg
     3241 tgctaaggga attagagcaa gaagggttac ttgttaatga agaagaccgt gtttatttga
     3301 caccaagagg gacctttttg gggaacaatg tgtttgagcg ctttttgttt gaaaaatagt
     3361 ttaaagaata tttgtttttt atctgaattt aaataaaaaa agttcaaaaa tacaataaag
     3421 gactattgaa acgttgatat aactggattt acatcaatta tttagaatta gcactcttgt
     3481 gtttagagtg ctaaaaaatg gagtctttct cttgacagga gaagggcttc ttgctatatt
     3541 tataagtgga ttagcactta gaatatatga gtgctaatga gaggtgagga agatgttaac
     3601 aaagcgacaa aacgacattt tacgtctgat catccaacac tatacgagta gtggcgtgcc
     3661 cgttggttcc aaaacattga tgtctgaggg agtcaaggcc agctcagcaa cgattcgcaa
     3721 tgatatgaaa gcattagaag atgaaggatt gctgttgaag actcactctt cttctgggcg
     3781 gattccatct gctttaggct atcgttatta cgtggatcat ttgttaaaac ctgctcgcgt
     3841 agcagaagat gatttgctgc tgattcgtca gtctctaggc agagaatttc atgaaatcaa
     3901 tgagattatt aagcaatctg ctgagatatt atctgagctg acaagctata cgactttttc
     3961 attgggacct gaaataaaag accgccgact gactggcttt cgtatcgtac ccttgaataa
     4021 tcgacagatt attgctatcg tcgtaacaga tatggggaat gtagaaagcc aagtgttcac
     4081 tcttcccgaa tatatgggaa gtcaggaact agaaaaaatg gtacagattg taaacgaccg
     4141 tctagtcgga gatcctctga tgacggtgta ccataaactt cgtacggaga ttccgatgat
     4201 tcttcataaa tatttccaaa cgacagaagg gatgtctcag ttatttgaca ccgttcttgg
     4261 tcatgttttt gaagataagg tttatgtcag tggacaaatg aatctcttgg attatgagcc
     4321 ccgtcaagat cttgatcagt tcaaatcgat gttttctttt atgaaagact cagacggact
     4381 tacacaaatg atcactccga tggatagcaa tattcatatc aagattggtg ctgaattagg
     4441 caatgattta ttgcagaata tgagtatgat tcaagcaagt tacgagatag atggtcatgg
     4501 aagaggtaca atagccttgt tagggcctac tagtatgcct tattctcgga tgttcggtct
     4561 agtcgatgtt tatcgaagag aactagcagc taaacttgct gattactacc gttcgcttga
     4621 cttgtcaaac tcgtaatgtg aataacgaag ctatttgcag ctgatcgttc tctctttctt
     4681 agtaagagca atcaaacagc tgactgaata atgaaaggaa gactgtatcg tgaaagaaaa
     4741 tcaagaagaa ctagataaag aaatgacaga tgctcagcca gaaccggaaa tcgatgtcga
     4801 agctgcagaa gattcgggta tttcagaagc tgaagcggaa gaattcgaaa cagcgaaatt
     4861 aaaagctgag ttagaagaaa tggaagataa atacttgcgg gctcgtgctg aaatcgcaaa
     4921 tatggcaaat cgaggaaaaa atgagcgtga gcaattacaa aaataccgtt cacaagattt
     4981 agccaaaaaa ttacttccat caattgacaa cctggaacgt gcattagcca cagaagtgtc
     5041 agatgatcaa ggggcaggtt tgaaaaaagg cgtggaaatg gtcttggaaa gtttgcgtaa
     5101 cgcactggaa gaagaaggaa ttgaaaaaat ccctgctaaa ggagaagcct ttgatcctaa
     5161 tcttcatcaa gcagtacaaa ctgttccagc gactgaagat acaccagccg atacgattgt
     5221 agaagtacta caagaaggct acaaattaca tgatcgcgtg ttaagaccaa ccatggtcat
     5281 tgttgcacaa taattgtgcg gatataaaac ttacactttc aattaaagaa ggagacgtta
     5341 attatgagta aaattatcgg tattgactta ggtacgacta actctgcagt agcagtattg
     5401 gaaggaaacg aagcaaaaat catcgctaac ccagaaggaa accgtacaac accttctgtt
     5461 gtatcattca aaaatggaga aatccaagta ggggaagttg caaaacgtca agctgtgaca
     5521 aacccaaata cgatttcatc aatcaaacgc catatcggtg aagcaggtta caaagtagat
     5581 gtagaaggta aatcatatac accacaagaa atctcagcaa tgatccttca atatatcaaa
     5641 ggattcgcag aagactattt aggtgaaaaa gtcgaaaaag cagttatcac tgtgccagct
     5701 tactttaatg atgcacaacg tcaagcaaca aaagatgctg gtaagatcgc tggtctagaa
     5761 gtagaacgta tcgtcaatga accaactgca gctgctcttg cctatggttt agataaaaca
     5821 gatcgcgacg aaaaaatctt agtattcgac cttggtggcg gtacttttga cgtatctatc
     5881 cttgaactag gagacggtgt ctttgatgta ttgtcaacag ctggcgacaa ccatctaggt
     5941 ggggacgact ttgataacaa aatcatcgac tacatggtag cagaattcaa aaaagaaaac
     6001 agcattgact tgtctcaaga caaaatggct ttacaacgct tgaaagacgc tgctgaaaaa
     6061 gcgaaaaaag atttatctgg cgtatcaagc acacaaatca gcttgccatt tatcacagca
     6121 ggagaatctg gaccattgca tttggaaatg acattgacac gtgcaaaatt tgatgaatta
     6181 acagctgact tagtagaacg tacaaaagta ccagtacgtc aagcgctaaa agatgcaggt
     6241 ttatcacaat cagaaatcga cgaagttatt ttagtcggtg gatctactcg tatccctgca
     6301 gttgtagaag cagtacgtaa agaaacagga aaagaaccaa acaaatcagt taaccctgat
     6361 gaagtagttg ctatgggtgc tgctatccaa ggtggcgtga tcactggtga tgtgaaagat
     6421 gttgttttac ttgacgttac accattgtca ttaggtatcg aaacaatggg tggagtgttc
     6481 actaaattga ttgaccgcaa tacaacgatt ccaacaagta aatcacaagt attctcaact
     6541 gcggcagata atcaaccagc agtagacatc catgtattac aaggtgaacg cccaatggct
     6601 gctgacaaca aaactctagg aagattccaa ttgacagata ttccagcagc tcctcgtggt
     6661 attccacaaa tcgaagtaac attcgatatt gataaaaacg ggattgtaaa tgtatctgcg
     6721 aaagatctag gtacacaaaa agaacaaaaa atcacgatca aatcttcttc aggtctaaca
     6781 gacgaagaaa tcgaacgtat ggtaaaagat gcagaagcaa atgcagaagc agataaagct
     6841 cgtaaagagg aagttgacct acgtaatgat gtagatgcat tgctattctc tgtggacaaa
     6901 acattgaaag aattagaagg caaagtggac gaagaagaag tgaaaaaagc agaaacagct
     6961 cgcgatgaat tgaaagccgc tgttgaagca aacaacatcg aagaaatgaa aactaaacgc
     7021 gatgcattga acgaaatcgt tcaaaacttg actgttaaac tatacgaaca agcggcacaa
     7081 caacaagctc aagaaaaccc agaagcagct caaggcggag cagatgatgt cgttgatgct
     7141 gattttgaag aagtcgatgg cgacgataaa taatcagttc actgaatttc gagagaaggc
     7201 caaagttgct actttggctt tttcttttga aaaatagttt gaagtatcgg tttttgtttc
     7261 aaacaaaata tgatatgata acaagcgacg tgaaaatgat gagaaccaat aggaggaaag
     7321 cctatggcaa caaaacgtga ttattatgaa gtcttagggc tctcaaaagg agcatcagaa
     7381 gatgaaataa agaaagctta tcgtaagctt tcgaaaaaat accatcctga catcaataaa
     7441 gaacctgatg cggaagaaaa attcaaagaa gtatcagaag catatgagat tttaagtgac
     7501 ccgcaaaaac gcgctgcata tgaccaatac gggcatgcag gcacagatcc aaattacggt
     7561 gctggtggag ctggtggcgg atttggtgga ttcggcggct tctctggtgg cggcttcggt
     7621 ggttttgaag atatcttcga ctctttcttt ggaggaggcg gtcggtcagt cgatccaaat
     7681 gcgcctcgtc aaggtgctga tttgcaatat acggtcgact tgtcttttga agaagcgatt
     7741 tttggtgtag aaaaagaaat caagtataat cgggaagaaa tctgtcatac ttgtggtggg
     7801 aacggtgcaa aaccaggcac acaaccaact acttgtcata aatgtcatgg tgcaggtacg
     7861 attaatgtag aacgccaaac accacttgga cgagtgatga gccgtcaaac ttgtgatgtt
     7921 tgtcatggga cagggaaaga aatcaaagaa ccttgtccaa cctgtcatgg ctcaggacat
     7981 gagaagaaag cacattcagt taaagtgaat gtaccagctg gtgtagaaga aggacaacaa
     8041 atgcgtttag ctggtcaagg agaagctgga gaaaacggcg gaccatttgg tgatttgtat
     8101 gtggtcttcc gtgtagaaga aagtgatatc tttgatcgtg aaggttctga aatttactat
     8161 gaattgcctt taagttttgt acaagcagct ttgggggatg aagtccaagt accaactgtc
     8221 catggagatg tgaaattgaa gatccctgct ggaacacaga caggtacgaa cttccgttta
     8281 cgtggaaaag gcgctccgaa gttacgtggt ggtgcaacag gcgaccaaca tgtcaaagta
     8341 aaactgatca caccgaaaaa tctaaatgaa caacaaagag aagcattacg tgcattcgct
     8401 gaagctggcg gcatcaaagt tgaagaacag caagaagacg gtttcttcga taagtttaaa
     8461 gatgcttttg gcgggaaaaa gcggaagtag tttttctagt aaaaacgcta agtcattaat
     8521 aattaaaaag gctctttgtc aataaggact gatgagttgt gcaaaatcaa
//
LOCUS       DAFEML010000085         8490 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFEML010000085
VERSION     DAFEML010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.087"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..173)
                     /locus_tag="LP468_002403"
     CDS             complement(<1..173)
                     /locus_tag="LP468_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081894.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="LP468_002404"
     CDS             complement(593..1714)
                     /locus_tag="LP468_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBL2081895.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="LP468_002405"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="LP468_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL2081896.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="LP468_002406"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="LP468_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL2081897.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSC"
     gene            complement(4304..5215)
                     /locus_tag="LP468_002407"
     CDS             complement(4304..5215)
                     /locus_tag="LP468_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2081898.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="LP468_002408"
     CDS             complement(5232..6239)
                     /locus_tag="LP468_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2081899.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="LP468_002409"
     CDS             complement(6236..8365)
                     /locus_tag="LP468_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2081900.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8490)
                     /locus_tag="LP468_002410"
     CDS             complement(8370..>8490)
                     /locus_tag="LP468_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2081901.1"
                     /translation="GQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2598 a         1728 c         1487 g         2677 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tgttgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg
//
LOCUS       DAFEML010000086         7832 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFEML010000086
VERSION     DAFEML010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.088"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..129)
                     /locus_tag="LP468_002411"
     CDS             complement(<1..129)
                     /locus_tag="LP468_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2081902.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDS"
     gene            402..2873
                     /locus_tag="LP468_002412"
     CDS             402..2873
                     /locus_tag="LP468_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2081903.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2976..4712)
                     /locus_tag="LP468_002413"
     CDS             complement(2976..4712)
                     /locus_tag="LP468_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL2081904.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4709..5413)
                     /locus_tag="LP468_002414"
     CDS             complement(4709..5413)
                     /locus_tag="LP468_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2081905.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5544..6047
                     /locus_tag="LP468_002415"
     CDS             5544..6047
                     /locus_tag="LP468_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL2081906.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6007..6345
                     /locus_tag="LP468_002416"
     CDS             6007..6345
                     /locus_tag="LP468_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL2081907.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6366..7784
                     /gene="ffh"
                     /locus_tag="LP468_002417"
     CDS             6366..7784
                     /gene="ffh"
                     /locus_tag="LP468_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL2081908.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
BASE COUNT         2509 a         1447 c         1646 g         2230 t
ORIGIN      
        1 agagtcatcc aattttcctt taataaactg cgcttgaacg cctttatatt ctttttcaat
       61 cagccattct tcatcaaaaa ataaatgttt atctgttaat ccgagtaatt ttctagtatg
      121 attatccatt gagagactcc tttggtagga tgacgttttg gtcgactaaa ttttaccaaa
      181 agtgagtctc tttttgagtt gaaacgaaga aaaagtgtta gtagaaaatc gccttcgatt
      241 ttccaccaac acaaaatatt atagaaccct ttttttttgc tatatgacag gaatgaaagg
      301 tgtttgcaag cttaatgtga ggaacacttt ccatatctgt tctatactgg ataggagaag
      361 tttggaaata tccagaaaac gaaatcaatc gaggtagcca catgaagaat aaatggataa
      421 atcgaagtaa aaaaaagaaa gtaacacaaa gatcatcaga taaagtcatc cgtctttttc
      481 catcgtataa agaaggatta acggcagatc aagtcaagga acgaatagaa aaaggtgcag
      541 caaataattc agtcgatccc acattcaaaa caaatcagca aatcgtattg gaaaacatat
      601 ttacgtattt caatttgatc tttcttatct tagccatttt gctttgttta gtagaatcct
      661 ataagaactt gactttttta ccagttatca tagccaatac aggaatcgcc atttttcagg
      721 aaattcgatc caaaaagatc ttggacgaac taaatgtttt aaatacagca aaagtcaatg
      781 tcatacgaga cgggatagaa caaacaatag atatagaaga ccttgtaata gatgacattg
      841 ttattttaga gactggatat caaattccag cagatgcaga ggtcgtggaa gggaaactgc
      901 aagttaatga ggctttattg acaggcgaag cagatgaaat aaccaaagaa ataggtgatc
      961 cattaatgtc cggcagtttc attgtttccg gaaaagctta cgcccgatta gacaaagttg
     1021 gagcagattc gtatatttcc cagctgacag tcaaagccaa gacaatggga gaaggagaac
     1081 agtcggagat gattgcttct cttaatcaat tgatcaaatg gattgggatc atcattattc
     1141 ctatcggtat cctgcttttt tctcaaagtt acttttttaa tggaaacacg atcaaagaaa
     1201 gtgtcgttgc aatggaagca gcattgatcg gtatgatacc tgaaggactg tacttgctga
     1261 cgacgattgc attagcatta agtgcgacta aactagcaaa gcaaagagtt cttttacaca
     1321 atatgaaaag cattgagaca ttggcaaggg taaatgtcct ttgtgtagat aaaacaggaa
     1381 cgatcacaga aaataaaatg tctgttcaaa aaatgatcgt ctctaaaaaa caagaaataa
     1441 tcagtcagtc agatcaattg gaagcatgca ttgctgacta tgcaaaagcg atggcaggag
     1501 acaatgcaac aatggaagct gttaaagcat attttacaaa aaccactgat caatcctatc
     1561 accatgttat tcctttttct tctgtccaaa aattcagcag tgtagcgttg gcagacaagg
     1621 tgtatgtttt aggagcgccc gaaatggttt tgcgcgatca attgccggaa tatgcggaag
     1681 agtttgtttc tttcgctgaa aaaggctatc gcgtgttggt ctttggtgtg tacgatggga
     1741 ttcttgaaga accagtattg acagaagcag tcacaccatt aggctatatt ctgattgcta
     1801 atcctatcag aaaagaagca agagccacat ttgattactt caaaaaacag caagtagcca
     1861 tcaaagtgat ttctggagat aatccgctca ccgtatccaa tgtagctgtc caagcaggga
     1921 tttcacatgc tgatcagtac gttgatgcat ctaaattatc agaagaagaa tatgaagcag
     1981 ctgtcgaaaa atatacagtt tttggacgcg tcaagccaga acaaaagaaa atcttcgttc
     2041 aattgataaa gcgtaacaat acagtagcta tgacaggtga tggcgtgaat gatattctag
     2101 ccatgaaaga agcagactgc agtatagcga tggcttccgg aaatgaagcc gccatgcagg
     2161 cctcacaagt ggtcttactt gattctgact tttcacgcat gccagaagtt gttgcagaag
     2221 gacggcgcgt tgtgaacaat attgagcgat cagccagctt gtttttagtg aagaatattt
     2281 tctccttttt gctctcactg ttttcagtga tctttgctct gacctatcct ttagaaccat
     2341 cacaaatcac attgattagt ttgtttacta tcggacttcc atctttcttg cttgctctag
     2401 aagaaaacaa aaagcgaatc agagggaaat tcatcatgaa tgtgatggaa aaagctgtgc
     2461 caggtggact aacagatatg atcgtagtcg gtgcgttggt gatctgcggg gtgactttga
     2521 atctaaataa aacagatgtt tctacagcat ctaccatgct tttgattgca gtagggttcc
     2581 tcgttctcta taaaatctgt tcaccgctga ataaattcag aagtcagatc attcttttct
     2641 gtgctagcgg taactttttt tcggtcatct ttttgcataa gctgttttca atcaccggta
     2701 tctcagctgt atcacttttg ctgttgagca ttctattttt ctcggcagat tcgattttta
     2761 ggcatttgac cacattggta gaatatttgt ttgaacgtaa aaatgaaaaa gagcaaaagc
     2821 cgtttagtcg cgtagctaaa aaatttctat cgatatttaa acgagaaaat tgacgaaaag
     2881 tatctcaaaa aagagtaaaa aagaacaacc actcgtgtat ctttcgaagc aggatgagtc
     2941 atccaacttt aaaacgcacg agcagttgct cttttttaca ttttcggaat ggtaacggtg
     3001 aaagtcgaac ctgttccaag atgactgtct acagtaatcg taccattaag gagttgcacg
     3061 tagtctttta caatcgctaa ccctaatccg gtcccgcctg aatgtcggct tcgcgccttg
     3121 tctacgcggt aaaaacgctc aaagatccgt tcctgatcct caatgtcgat acctatacca
     3181 aagtcttgga cagaaaacga tagatcatct gttgcctgat agcggataat aatctcgctg
     3241 tcgctttttg aatattggac agcattttca atcagatttt tgataattgg ataaaggata
     3301 tctgttttag tagtaaatgg ttcgttcttt ccaatcaatc gaatcgtcaa ccgtttcttt
     3361 tcgatgattg gctgataatt ttgaacgatt tgctggaaat aaggttctgt ataaattgtc
     3421 tggatctcgt aagaattctc gccatctttt gacagctgga tgatttcccg aatcagttta
     3481 tctaaccgga tcgcatcttt ttgcatgatc tcaagaaaag aagtcagagt ttgcgggtca
     3541 tcttttgcac catccagtaa agtctcggta aaaccaatca gtgaagtcac aggagttttt
     3601 aattcgtgag agacgttgcc aacgaaatcc ttttgtagct tttctaaacg tcgcactttc
     3661 gttaagtcat acgccacccc tagaatctgt ccggtacctt ctgaattagt aaagtagcgc
     3721 aaactcaagt ctaatgtctg ccgaccttct gtaagggtga tctcctgatg gatcagcgga
     3781 tgctcaggag tcacttgatg aatcagctga atgagttttg gctcttgaat gacttctgtg
     3841 taccgctgtt caggttgata gcttaccacg tttaaatgta gctgcatctt tggattaagc
     3901 agtagtaaac gagaatcagc atcatcaatc aggaatacgc caatcatcag ttcgttcagt
     3961 aacgtatata attgctcttc tgtggtagta cacgcccgat acatcttact catttgttcg
     4021 ctcaacgcat taatcgtctg atacaattct tcccattgat cgggtgtttg catgattact
     4081 tccgcctgat taggattttg caccattttt tttagtacgg gcagcacggt tttcaatggc
     4141 tggttttttt gatagatcag ataatagatc attcctgcaa gaacaaggaa gaaagacaga
     4201 aagaagaaaa agacccaacg gcgaaaactc tcagttctcg gtaaaaaaac gcttgtcggt
     4261 tctgcgatac gtaaaatggc ttctaactgg ccactttttt tgactggtaa tgcgacatat
     4321 aaaagatcct cattcaaagt agtacttttg cgcaaagcgc tacctaggtt cccaccattc
     4381 aatacggctt tgatttcggg acgggagttt cgctgttcat tcaatgtttc attgtttgtg
     4441 tcaaataaga tctttccagt agcatccatt aaagtaatcc gttcgttcga ctgatggacg
     4501 aattcttcca aagcagtttt gttttgcgct gcttggaggt tttcgacatc taattgccgg
     4561 atcagcagtt gtgctttttt tgtcaggtag ctttcttgct gttccacgat ctgctgttga
     4621 aaataatggg aaatcaattg ccagccacca aaaaacaaac taactaaaag aataagaaag
     4681 aagagacgtt cataaatttt tttccatttc atcgtttggg ttcctgaaac ttatagccaa
     4741 atcctctaat agtcaccaag tactttgggt gttttggatc tcgctcgatt ttttctcgca
     4801 aatgactaac gtgtacatct acgattcggc tttgtcctgc gaagtcaaaa ttccaaatgc
     4861 ggtctagcaa tgtgtctcgg tcgatcacac ggtcttttcg tttcatgaaa taaacaagta
     4921 attcaaattc tttcggtgtt agttcaatca gatggtcgtc tacggtcact tgataattgg
     4981 tcaaatcagc agtgatttgt ccaatcgata gatattcagg ctcagcttca tcttttgatt
     5041 gcttacgagg ttcaattcgt ctgaatattg ctttcatacg ggctaatact tcgcgaggac
     5101 taaatggttt ggtcaaatag tcgtcagcac ctatttctag gccaatgatc cgatccactt
     5161 ggtcatcttt agccgtcagc atcaaaatcg gtgtttcatt tttttcttga cgcagccgct
     5221 gagtgatctc catgccatcc atcgttggaa gcatcacatc taaaatgatg aaatcaaatg
     5281 attgttctaa tgctaattct aatccttcgc ctccatctgt ggcactggtt accttgtagc
     5341 cttctttttc caaattgaac gtcaagagcg ttacaataga aggttcatca tcaacaacta
     5401 gtattttttt cattcaaatc tcctttaaat aggtttcatt ctgtttatat tttagcatag
     5461 aatcagtaca aagggctatt ttacaaaaga aataaatggt ataataggaa ggcactttgc
     5521 tgaatagaaa ggaagagcag tcaatgattg gaatcagtgc atgtttaggc ggtctggcct
     5581 gtcgctatga tggacagaaa aaagaagtac cagaattgat ggaactagtt gaaactggag
     5641 aagctgtcat ggtctgtcca gaagtgatcg gcggattacc aattcctaga gatcccgctg
     5701 aaatcattgg tggaaatgga ttcgatgtgt ggaaagatca agcaaaagta tggacgacaa
     5761 gcggcgaaga tgtaacggaa gcgtacaaaa atggcgcgat caaagcctat caaaaattgc
     5821 aggaaaaaca cattgatcta gtcatcatga aggaaaaaag cccttcatgc ggaacccatt
     5881 cgatttatga cggaagtttt tccggaataa aaaaaaatgg tgccggagtg gctactgctt
     5941 attttattca gcaaaaaatg actgtgctct ctgatgaaga atggctgaaa actagaggtg
     6001 agcagaatgg aaatcgaaaa gaccaatcga atgaacgcgc tctttgaatt ttattcgacc
     6061 ttattgacag aaaaacaaat gaactacatg gaattatatt atgcagatga tttttcatta
     6121 ggtgagatcg cggaagaata cgaagtaagc cgacaagcag tatatgacaa tatcaagcgg
     6181 acaagcaaga tcttggagga ttatgaaaaa aaactccatc ttttttctaa ttatattgtt
     6241 cgagaacagg tattggaaaa tatgactgca tatattacag ataagtaccc ggaagataaa
     6301 aaactacttg aatatgtaca gcaaattcaa gcaatcgaag aataaataaa aggaatgaag
     6361 aaaatatggc atttgaaagc ttaactgaac gtctccagca ggcgatggga aaaataagaa
     6421 aaaaaggaaa agtatcagaa gctgacgtaa aagaaatgat gcgggaaatc cgccttgcct
     6481 tactagaagc cgatgttaac ttgcaagtag tcaaagattt tactaagcgc gtacgcgaac
     6541 gtgcggtagg ggcagaagtg ctggaaagtt tatcacctgc acaacaaatc gtaaaaatcg
     6601 ttgatgaaga attgacgatc acacttggtt ctgaaacagc agagttaaat aaatcaccaa
     6661 aaataccaac tgttatcatg atggctggtc ttcaaggggc aggtaaaacg acctttactg
     6721 gtaaattagc caattattta aagaaaaatg aaaatgctcg tccgctccta atcgcagggg
     6781 acgtatatcg accagctgcg atcgaccaat tgaaagtatt aggtcaacag ctagacgttc
     6841 ctgtatttga tatgggaact gaagtcagcc cggtagagat cgtccgtcaa gggatggagt
     6901 tagcaaaaga aaagaaaaac gactatgtat tgatcgatac ggcaggacgt ctgcatatcg
     6961 atgaaacatt gatggatgag ttgaaacaaa tcaaagaatt gacgcaacca aatgagattt
     7021 tgcttgttgt cgatgccatg actggtcaag atgccgtcaa cgtagctgat agcttcaacc
     7081 agcaattagg tattacaggg gtcgtcatca ctaaacttga tggggatact cgaggcgggg
     7141 cagcactatc gatccgctca gtgacaggcg caccaatcaa attcatcggt tctggtgaaa
     7201 aattgactga cttagaagta ttccacccag atcgtatggc tagccgtatc cttggtatgg
     7261 gggatatgct gacattgatt gaaaaagcgc agcaagacta cgacgagaaa aaagcggaag
     7321 aacttgcaca gaaaatgcgg gaaaattcat tcgatttcaa tgactttatt gaacagcttg
     7381 atcaagtgat gggtatgggc ccactggaag atctaatcaa aatgatccca ggaatgaatc
     7441 aagtccctgg aatcgaaaac gtcaaggtag atccaaaaga tgttgaacgc aaaaaagcga
     7501 tggtttattc tatgacgcca gcagaaagag caaatcctga tctgttgaac ccaagccgtc
     7561 gtcgccgaat tgctgccggt tctggaaaca gtgttgttga agtgaatcga atgatcaaac
     7621 aattcaagga atcaagaaaa atgatgcagc aaatgtccaa aggggatatg aacatcccag
     7681 gtatggacca aatgtttggt tcaggcgtca aaggaaaact aggcaaaatg gcgatgaatc
     7741 gaatgatcaa gaaaaataag aagaaaaaga aaaaacggaa ataagatgaa aaaaacagct
     7801 tcggtacaga ctgaaaatgt ctactgccgg ag
//
LOCUS       DAFEML010000087         7760 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFEML010000087
VERSION     DAFEML010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.090"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP468_002418"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP468_002418"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL2081909.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="LP468_002419"
     CDS             complement(2032..3285)
                     /locus_tag="LP468_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2081910.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="LP468_002420"
     CDS             complement(3291..4214)
                     /locus_tag="LP468_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2081911.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="LP468_002421"
     CDS             complement(4435..6927)
                     /locus_tag="LP468_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL2081912.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="LP468_002422"
     CDS             complement(6934..7401)
                     /locus_tag="LP468_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL2081913.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="LP468_002423"
     tRNA            complement(7537..7610)
                     /locus_tag="LP468_002423"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="LP468_002424"
     tRNA            complement(7668..7741)
                     /locus_tag="LP468_002424"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2162 a         1691 c         1246 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acaaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DAFEML010000088         7699 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFEML010000088
VERSION     DAFEML010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.091"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            544..1107
                     /locus_tag="LP468_002425"
     CDS             544..1107
                     /locus_tag="LP468_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2081914.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="LP468_002426"
     CDS             complement(1386..1673)
                     /locus_tag="LP468_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2081915.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="LP468_002427"
     CDS             complement(1663..1992)
                     /locus_tag="LP468_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2081916.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="LP468_002428"
     CDS             2297..2626
                     /locus_tag="LP468_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2081917.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="LP468_002429"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="LP468_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2081918.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /locus_tag="LP468_002430"
     CDS             complement(3551..4462)
                     /locus_tag="LP468_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL2081919.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="LP468_002431"
     CDS             complement(4890..5498)
                     /locus_tag="LP468_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2081920.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="LP468_002432"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="LP468_002432"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2081921.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="LP468_002433"
     CDS             complement(6528..7496)
                     /locus_tag="LP468_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2081922.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2351 a         1532 c         1281 g         2535 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tggttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatt
//
LOCUS       DAFEML010000089         7672 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFEML010000089
VERSION     DAFEML010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.092"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(82..354)
                     /locus_tag="LP468_002434"
                     /pseudo
     CDS             complement(82..354)
                     /locus_tag="LP468_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            536..871
                     /locus_tag="LP468_002435"
                     /pseudo
     CDS             536..871
                     /locus_tag="LP468_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            1036..1263
                     /locus_tag="LP468_002436"
                     /pseudo
     CDS             1036..1263
                     /locus_tag="LP468_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            1389..2360
                     /locus_tag="LP468_002437"
     CDS             1389..2360
                     /locus_tag="LP468_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2081923.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            2501..3814
                     /locus_tag="LP468_002438"
     CDS             2501..3814
                     /locus_tag="LP468_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2081924.1"
                     /translation="MKRRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNDKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIISLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3857..4723
                     /locus_tag="LP468_002439"
     CDS             3857..4723
                     /locus_tag="LP468_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2081925.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4720..5568
                     /locus_tag="LP468_002440"
     CDS             4720..5568
                     /locus_tag="LP468_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2081926.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5582..7054
                     /locus_tag="LP468_002441"
     CDS             5582..7054
                     /locus_tag="LP468_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBL2081927.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWINDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMTAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPHHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            7071..>7672
                     /locus_tag="LP468_002442"
     CDS             7071..>7672
                     /locus_tag="LP468_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2081928.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKDKRLQK"
BASE COUNT         2378 a         1321 c         1622 g         2351 t
ORIGIN      
        1 tccatgttcc ccactcctca agtgttttct ttagtatacg cctataggag gaaaaacgaa
       61 tacaatttaa ctcaatttat atagtatttt taatgctact tttttctgtt tcataaaggt
      121 aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg caacaatgac
      181 acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcact ggatatcttt
      241 accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca ttgccaattg
      301 tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg ccataaaaac
      361 tccttttaaa aaatgatata atttacatgt aaaatttact tgtagcttta ctgttatcat
      421 agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt tttgaatgaa
      481 tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta gctcggaaca
      541 gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg gtagaaaagg
      601 caaactttat caaacttatt acgacggtat ggagaaacag ctcaacgcat taggattagt
      661 aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg aacaaattaa
      721 aacggaaggg ttcgactgtt ccgaagaagt gatacgcaag caatctccat taattagtga
      781 tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat cgaatggaat
      841 actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt cctaccgtgc
      901 attttcgcac ggatgttcca gatactattt ttgaatgtat aaaactgaaa acacaagaat
      961 cctattaaat caacgattct tgtgttttta atttttcact accgtgcatt ttcgtttcta
     1021 tgttccatgt accccaatct tgaaaaatta attaaagact tatataaagc cattgatgac
     1081 ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat tggtcctgtt
     1141 taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga tgaaataaaa
     1201 ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc tgaatacgaa
     1261 aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat attcctgcta
     1321 atttggaatc gtttccttct tttggtataa taatacctga aattcttttg agaggagttg
     1381 ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt ggtgtgggta
     1441 cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa aaagtaatgg
     1501 ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg aaaacgaata
     1561 gcagcaatac aatagctctt attttaccta cgatttggca tcccttcttt tccgagtttg
     1621 cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg tgtaatgcga
     1681 acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt aaagtagacg
     1741 gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat ttaccatttg
     1801 tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat aattatttag
     1861 gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg tgctatgttg
     1921 ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt tacaatattt
     1981 gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt agcaatttgg
     2041 aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt tttaccatca
     2101 atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag gaagcaccta
     2161 aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa gactatttac
     2221 tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa acactcatgg
     2281 cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc tttcacgctg
     2341 gagaaacgac taaagagtaa aaaaccggtt tataacgatt ttttttgaga taggttgaca
     2401 gaaagtggtt tcaatgatat cttaaaacca attaattgga aacgttacca attaattgga
     2461 aaataaaacg gaaacgtttc aaaaaatagg aggaacatcg atgaaaagga gaatgttagc
     2521 aattgcagca attttagcat taacagctgg aggacttgca ggatgtggca gtaaggagaa
     2581 aagttcaggc agcagtgatt caggagaaat taagatttgg gttcagtttt ctgatgaaac
     2641 gcctgaagga aaagcttggg cagagattgt gaacaatttt aatgatgaat acgagggtga
     2701 atataaagct gttactgagt atattcctcg tagcggaagc ggcggtggat atgaggataa
     2761 agtaaatgct gcaattacaa ccaataccct tcctgatgtt attacgttag atggaccgaa
     2821 tactgcagct tatgctcatt caggagtcat tgctccatta gatgattatt tgaaagatgc
     2881 ggacatggat gatgtattag acagcattat tcagcaagga acctacgatg gcaaaatgta
     2941 tgcgtttggt ttctcagagt ccagtgtggg tgtctattac aataagtcgt tgttcaaaga
     3001 tgctggaatt acagaagatc aattgccgac gttagaagat ccttggactt ggacggaatt
     3061 tcaagcaatt tgccaaaagc tgactgataa atacaaaacg cctgcaattg atatgcaaat
     3121 ggcgtcggga gacgaaatgc tgacctacgc atatacacca tttgtatggt cgaatggcgg
     3181 cgatgtcgtt aatgctgatg gaaccaaagc cgaagactat tttaacgata aaaaatccgt
     3241 tgaagcgttg gaatttattc aagaattggt tgaaaaaggt tacaccacaa tcagtcctat
     3301 tgaaaaagga tttgaaactg gcaaatatgc catgctgctg agcggttctt ggacaatggc
     3361 agatttagag gaaaactatc aagagattga ttatggtatt ttgccttacc ccgtttcaga
     3421 tgcaactggg gagttagttt caccaaccgg cagctggcag ttagcaatga ctgagaaaac
     3481 agagaaaaag gatgcttctg cggcctttat taagtttgca accagtacag aatctagtcg
     3541 tattattagt ttagggaaca gtgttctacc tatcagaaat tcaacagttg atttaattaa
     3601 agatgaagtg tcggaaggaa tgcaggtatt aattaagcaa aaccaaattt ctggacatgc
     3661 ccgcccagtg gttgtagctt atccgcaagt atctagagca ttccaacaag cagttcaaga
     3721 tattagctac ttcgaggaaa acccagatgt acaaaaagta gcagatagtc gcgctgctga
     3781 aatgcaacag gcaattgata cttcactaaa atagaagttt ctaaaggggg ccaatcaagt
     3841 gttaaaaaaa ccgacaatga aagacaattt gataggttac ggctttctag cgccagcttt
     3901 gctgctgctg acgatttttc tgatcatacc cgtaatcatg gtaatttatt atgcctttac
     3961 tgattattat ttgttaacgc cagatgctag acaatttatc ggcttagaaa attttaagcg
     4021 actgttcgct gatccaattt ttgtaaaaag tatttggaac acggctaaat ttgttgtttg
     4081 gattattccg gtccaattag gggcagcttt aggaatggca cttattatca acaaaaatcg
     4141 taaaggaaat atctttttta aagtagcctt ttttgcgcca gtcgtgatgt ccttagtcgt
     4201 tatttcgatt ttatggttgt acttgttaaa tcctaatgaa ggtctggtta atacgctatt
     4261 tgcaaagatt ggaattgctt cgcagccttt tttgactagt cccaaacaag caatgtatac
     4321 gcttgttttc gtatcggcat ggcaaggtgc aggatatcag atgctgctgt ttttaggggg
     4381 aatgcaaaat attccgcaag acgtttatga ggcagccgaa attgatggtt tttctaagtt
     4441 tcagcaattt cgctatatca ccatgccatt attaaagccc acggcgattt ttattttact
     4501 taccacattg atttcggcct ttaaactaat cattcagcca atggtaatga ctcaaggtgg
     4561 accaatgaat tctactatga caatggttta ttacatttac caaactggat ttacagaccg
     4621 tatggtaggc tactccagct ccattgcgtt aatctttacc accatgattg gtttaattac
     4681 aattgctcaa agaaaattgg taaaggagga tgatccagca tgaccaagaa atttggaccg
     4741 ctaatgatcg tagaatattg tttgctgttc cttttagcgg cattattcat tttcccaatg
     4801 ctgtggatgg tagtttcctc tatgaagcct gaagcagatg tctatcaaaa tttagcttcc
     4861 ttcaaagctt ttttacctag tttgaatcca gctaattggt ttaaaactta tcaagaagtt
     4921 atttcccggt tcagtgtggg aacttattta ttaaacagta ttttttatgg tttaaccttt
     4981 gcctgtgggt caatcattgt aaactctttg gcgggttttg cctttgcgaa ggttaatttt
     5041 tcaggcaaga aaattatctt tggagctttg ttagctctgc tgattgtccc gatggagacg
     5101 gttttaattc cgcaatttac catcgttaat tcactaggct tagtgaatac tcgcttggca
     5161 gtgattttac cagcgatggc cagcgcgttt aatatctatt tgtttagaaa tttctttatc
     5221 gcgattccag aagaaatcat tgaatcagcg aaattagatg gtgcaaatat tgttaaaatt
     5281 ttctttcaca tcatgctgcc aatgtctaaa ccagccatag ccacagtagg tgtcttatcc
     5341 tttatctcca gctggaatga ttatatttgg ccgttaatgg tcttaactga cagcagcaaa
     5401 ttttcaatgc aagtggcaat tactacgatc aatactacac agccagttta tatcaatcaa
     5461 gtgatggctg ttttaaccat tgcaacgatt ccactgatta ttgtttatat cgttgcacaa
     5521 aaatatattc tgcagggact tggcggttct ggaacgggta taaaatagga gtgaatagtg
     5581 aatgttgcaa aaacttttaa aggccaatga gtttattgag aaaaatgctc aaacagtcaa
     5641 tcaagaatac cggaataaat ttcatttgat ggctccgatt ggctggatca atgatccaaa
     5701 tggttttgtt tattatcaag aggagtatca cttgttttat caatattatc cttacgacag
     5761 catctgggga ccaatgcatt ggggccatgc taaaagcaag gatctaattc actgggagca
     5821 tttgccagta gcactggcac caggtgaaag ctatgacaag gaaggctgtt tttccggcag
     5881 tgccatagaa aaggatggca agctgtattt gatttataca ggacacaatg ttgtggaagg
     5941 gcaagttcga caagttcagt gtttggcagt ttcagaagat ggcattcact ttgaaaaata
     6001 tgccggaaat ccaatcatcg cagaagatca cttagcttct gttgcaacga ccgaagattt
     6061 ccgcgatccc aaagtgtttc agcgaaaaga agactatttt actgtagtcg ctactaaaac
     6121 tgcagatgct cgtggacaaa ttgtgatgtt ccattccaaa gatttactaa cttgggagtt
     6181 ttattccgta ttgctggagg gaactccaga acaaggcatt gtatgggaat gcccagactt
     6241 gtttgaacta gatggcaaag aagtcttgat tctttctcct attcaaatga ctccacaagg
     6301 caatgcttac caaaatacga actcaactgt tgctttcatt ggtactgtcg attggcaaac
     6361 aggcaaattt ctagtagaga attttcatga aatcgatggc ggtttagatt tttatgcccc
     6421 ccagacctgt gaaaacgaag caggccaaag aataatgact gcttggatgc aaatgtggca
     6481 gcgtaaaata cctacgaatg atctgggcca tggttggtca ggttccatga ccttgcctag
     6541 agagctgagg gtggctgata atcaattgtt gcaacggcca gtttcatcaa tttatcaagt
     6601 aattgatccg caggaaagga ttgaatgggc gaagactgaa gagaatcgat tcttactgaa
     6661 ggacttagta tatgaccagc actatttacg cttggaaatc aatttaaaac aggcaacgaa
     6721 actagaactt cactatgcga agggacccca ccatacatta ctgcttaact atgatgttga
     6781 acgggagtgc tttactgctt ccagggaaca catgccgtat gatttatcag gagctgaaaa
     6841 ggaagtgttg aaaaagcgca gtgtgacgat tcctttggaa aataattgtc taaccatcga
     6901 aattttccgt gatacttcag ctattgagct ttttctaaat gatcgtctga ctatgagtac
     6961 aactttttat gagacagaaa aaggacagga ttttcttttg ctggcagaca gtgaagtaac
     7021 cttttcattg gaaagcggct taattaatct atagaaggga gagctcagtg atgatttatg
     7081 gttcaatcga agcaggcggc acaaaatttg tgtgtgccat tggcgatgaa gaaatgacga
     7141 tcaaggaaag agtgagcttt ccgacaacga cacctgagga aacaatgcct ttagtcattg
     7201 acttcttcaa acaataccaa gcagatttag cagggattgg gattggctca tttgggccta
     7261 tcgatatcca tcgcgattcc gccacttatg ggtacattac ctcgaccccg aaattggcat
     7321 ggcaaaattt tgatttcatc ggtaccatga aaaaagaatt tccgatcccg atttcttgga
     7381 caacagatgt caatgcggct gcctatggtg agtatgtctt cggcagtggc aaaggattga
     7441 gcagtgtcgt ttactatacg atcggtacgg gtgttggcgg cggtgcctta caagaagggc
     7501 gctttatcga agggtttagt catccagaaa tggggcatat gctcgtcgtc cctcatccaa
     7561 aagatgactt tgctggcagc tgtccatttc atggcaactg tttagaaggg atggccgctg
     7621 gacccgccat cgaaaaacgc ttagggaaaa aggacaagag gttgcagaag at
//
LOCUS       DAFEML010000090         7623 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFEML010000090
VERSION     DAFEML010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.093"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(14..706)
                     /locus_tag="LP468_002443"
     CDS             complement(14..706)
                     /locus_tag="LP468_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2081929.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="LP468_002444"
     CDS             complement(1143..1712)
                     /locus_tag="LP468_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2081930.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="LP468_002445"
     CDS             complement(1786..2109)
                     /locus_tag="LP468_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081931.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="LP468_002446"
     CDS             complement(2263..3075)
                     /locus_tag="LP468_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081932.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="LP468_002447"
     CDS             3429..4277
                     /locus_tag="LP468_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL2081933.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="LP468_002448"
     CDS             4422..5363
                     /locus_tag="LP468_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL2081934.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="LP468_002449"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="LP468_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1511 c         1370 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgt tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aac
//
LOCUS       DAFEML010000091         7596 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFEML010000091
VERSION     DAFEML010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.094"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(940..1353)
                     /locus_tag="LP468_002450"
     CDS             complement(940..1353)
                     /locus_tag="LP468_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL2081935.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="LP468_002451"
     CDS             complement(1809..2294)
                     /locus_tag="LP468_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081936.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2678)
                     /locus_tag="LP468_002452"
     CDS             complement(2433..2678)
                     /locus_tag="LP468_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL2081937.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2871..3671
                     /locus_tag="LP468_002453"
     CDS             2871..3671
                     /locus_tag="LP468_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2081938.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3690..5558
                     /locus_tag="LP468_002454"
     CDS             3690..5558
                     /locus_tag="LP468_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2081939.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5551..6042
                     /locus_tag="LP468_002455"
     CDS             5551..6042
                     /locus_tag="LP468_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL2081940.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6030..6584
                     /gene="srlA"
                     /locus_tag="LP468_002456"
     CDS             6030..6584
                     /gene="srlA"
                     /locus_tag="LP468_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL2081941.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6602..>7596
                     /locus_tag="LP468_002457"
     CDS             6602..>7596
                     /locus_tag="LP468_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL2081942.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1214 c         1443 g         2233 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaag
     2641 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     2701 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     2761 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     2821 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     2881 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     2941 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     3001 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     3061 tagaagaagg gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata
     3121 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     3181 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     3241 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     3301 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     3361 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     3421 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     3481 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     3541 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     3601 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     3661 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     3721 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     3781 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     3841 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     3901 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     3961 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     4021 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     4081 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     4141 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     4201 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     4261 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     4321 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     4381 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     4441 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     4501 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     4561 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     4621 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     4681 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     4741 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     4801 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     4861 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     4921 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     4981 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga
     5041 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     5101 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     5161 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     5221 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     5281 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     5341 ctgatcaagg tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg
     5401 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     5461 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     5521 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     5581 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     5641 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     5701 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     5761 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     5821 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     5881 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     5941 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     6001 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     6061 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     6121 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     6181 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     6241 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     6301 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     6361 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     6421 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     6481 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     6541 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     6601 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     6661 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     6721 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     6781 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     6841 aatttatcct aaaaaaggga taccaaccat caatatcgtt cccacaggaa aaagtggccc
     6901 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     6961 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     7021 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     7081 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     7141 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     7201 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     7261 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     7321 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     7381 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     7441 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     7501 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     7561 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DAFEML010000092         7428 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFEML010000092
VERSION     DAFEML010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.095"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            162..392
                     /locus_tag="LP468_002458"
     CDS             162..392
                     /locus_tag="LP468_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL2081943.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="LP468_002459"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="LP468_002459"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2081944.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="LP468_002460"
     CDS             1803..1979
                     /locus_tag="LP468_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2081945.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="LP468_002461"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="LP468_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL2081946.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2594..3061
                     /locus_tag="LP468_002462"
     CDS             2594..3061
                     /locus_tag="LP468_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2081947.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="LP468_002463"
     CDS             3146..4030
                     /locus_tag="LP468_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2081948.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="LP468_002464"
     CDS             4144..4380
                     /locus_tag="LP468_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL2081949.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="LP468_002465"
     tRNA            4468..4548
                     /locus_tag="LP468_002465"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="LP468_002466"
     tRNA            4555..4626
                     /locus_tag="LP468_002466"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="LP468_002467"
     CDS             4751..4921
                     /locus_tag="LP468_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081950.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="LP468_002468"
     CDS             5141..5848
                     /locus_tag="LP468_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2081951.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5908..6552)
                     /locus_tag="LP468_002469"
     CDS             complement(5908..6552)
                     /locus_tag="LP468_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL2081952.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6679..6966
                     /locus_tag="LP468_002470"
     CDS             6679..6966
                     /locus_tag="LP468_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081953.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7074..7394
                     /locus_tag="LP468_002471"
     CDS             7074..7394
                     /locus_tag="LP468_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2081954.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
BASE COUNT         2464 a         1195 c         1598 g         2171 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcttattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaacaatt tggaaaatag cttcttatat tttgcaaaat tgtgagttat
     2461 tgccgaagtg ttggattttg aacaccgtca aaaaaaggtt gtgaaaaata cgggtagcac
     2521 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5881 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5941 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     6001 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     6061 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6121 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6181 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6241 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6301 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6361 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6421 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6481 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6541 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6601 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6661 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6721 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6781 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6841 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6901 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6961 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     7021 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     7081 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7141 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7201 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7261 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7321 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7381 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaa
//
LOCUS       DAFEML010000093         7398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFEML010000093
VERSION     DAFEML010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.096"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..572
                     /locus_tag="LP468_002472"
     CDS             <1..572
                     /locus_tag="LP468_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2081955.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="LP468_002473"
     CDS             576..1217
                     /locus_tag="LP468_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081956.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="LP468_002474"
     CDS             1214..2131
                     /locus_tag="LP468_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2081957.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKESLNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="LP468_002475"
     CDS             2128..2799
                     /locus_tag="LP468_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2081958.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="LP468_002476"
     CDS             complement(3340..3828)
                     /locus_tag="LP468_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL2081959.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="LP468_002477"
     CDS             complement(4029..4295)
                     /locus_tag="LP468_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2081960.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="LP468_002478"
     CDS             complement(4295..4558)
                     /locus_tag="LP468_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2081961.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="LP468_002479"
     CDS             5034..5219
                     /locus_tag="LP468_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2081962.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="LP468_002480"
     CDS             complement(5361..7184)
                     /locus_tag="LP468_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL2081963.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
BASE COUNT         2217 a         1555 c         1417 g         2209 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaatccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataa
//
LOCUS       DAFEML010000094         7392 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFEML010000094
VERSION     DAFEML010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.097"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            291..1214
                     /gene="truB"
                     /locus_tag="LP468_002481"
     CDS             291..1214
                     /gene="truB"
                     /locus_tag="LP468_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL2081964.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1218..2159
                     /gene="ribF"
                     /locus_tag="LP468_002482"
     CDS             1218..2159
                     /gene="ribF"
                     /locus_tag="LP468_002482"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL2081965.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2511..3296
                     /locus_tag="LP468_002483"
     CDS             2511..3296
                     /locus_tag="LP468_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2081966.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3309..4160
                     /locus_tag="LP468_002484"
     CDS             3309..4160
                     /locus_tag="LP468_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL2081967.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4284..4736)
                     /locus_tag="LP468_002485"
     CDS             complement(4284..4736)
                     /locus_tag="LP468_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2081968.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(5201..5569)
                     /locus_tag="LP468_002486"
     CDS             complement(5201..5569)
                     /locus_tag="LP468_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL2081969.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5719..6201
                     /locus_tag="LP468_002487"
     CDS             5719..6201
                     /locus_tag="LP468_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL2081970.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6238..7248
                     /locus_tag="LP468_002488"
     CDS             6238..7248
                     /locus_tag="LP468_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL2081971.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
BASE COUNT         2502 a         1184 c         1537 g         2169 t
ORIGIN      
        1 aaaagactgg aagaatggcc agtctttttt ttcgtttttg ggaagtgaaa accaaactat
       61 ttacctgtaa gccacccata aatccaatca aatggtgcaa agaaaaaatc ttccattcta
      121 ttccctcctt taaaaaagca taacatgatt tctatttacg tgagcatgaa ttttgttacg
      181 tttttattgc cgaaaaataa aaaccgttca ttatgatgtc aaattcgtca gtaattgatg
      241 caatgtgtta taataattca gttaaatcaa aaatgaaatg gagaaaagac atggacgggt
      301 tattaccttt atggaaagaa cgcggaatga caagtcatga ttgcgtattc aaattaagaa
      361 aaatcttaca tacgaaaaaa atcggacatg ggggtacgct tgacccagac gtagacggtg
      421 tgttgcccat ttgtattgga aaagccacaa aagttatcga atatttgaca gattctggga
      481 aaatctatgt aggcgagata actctaggtt tcagtacaac gacggaagat cgatccggag
      541 aacgggtaga aacaaaacca gtagatatgt ctttatctga aaaaaaaata gatgaagtga
      601 tggcttcatt tattggtgag atcacccaga taccaccaat gtactcagcg gtaaaagtca
      661 acggtaagcg gttatatgaa tatgcccgca ataatgaaac agtggagcgt cctgttagaa
      721 aggctcagat ttaccgtttt atccggacaa gtgaattgac aagagacgaa gtgacaggaa
      781 ccatttcttg gcgcttcgaa gtagaatgcg ggaaaggaac ctatgtccgc acattagctg
      841 tagatacagg caagaaactt ggttaccctg cgcacatgtc tgatctgacc cgaacagcaa
      901 gtgccggtat gtcccagaag gatgctctga cattagaaga agtagctcaa gctgtgaaaa
      961 atgggacaat cgatgattgt ttgctgccaa tagaaaaagg agtggaacgg ttcaaacgag
     1021 tagatattac tgatgaagta tggcagaaag taaaaaacgg tatgagactt gattatactg
     1081 tatttgcgct cccagaaatg ccgtcagaag aaattgcttt gttttataaa ggaaaagttg
     1141 tcagtattta tcagccaaac ccgaaagaaa aaaacaaatt aaaacctagt aaagtattga
     1201 gaaatgagga ataacgaatg aatatcatca agatcagaca tccttaccaa tcagaacaaa
     1261 ttccagaaga cgatgtcgtt ttagtgctgg gatttttcga cggcgtgcat atcggacacc
     1321 agaaagtcat aaagacaggt atggaaattg cacaaaaaga aggattgaaa ttagcattga
     1381 tgactttcaa tcagcatcca tctattgtct ttaaaaagat cgatcctagc agcgtgaaat
     1441 atttgactag ccttaagcaa aaagaagaaa aaatggccgc tttgggtata gattatttat
     1501 atgaagttga ttttacttct tcttttgctc atttagcacc gcaggaattt gttgatcaat
     1561 acatcgtagg gttacatgca aaatatgctg tttccggttt tgattatacg tatggaccaa
     1621 aagacattgc agatgtcgct cattttcctg aatatgccaa aggaagattc aaaatcgtca
     1681 cagtttctaa agaagaagaa caaggtgaaa aaatcagctc tacccgtatt cgtggattac
     1741 tagacagcgg acaagtaaaa gaagcagcaa aactattagg ttgcacatat gaggtagaag
     1801 gggtagttgt ccatggcgat gcacgaggca gactactagg attccctaca gcaaatgtca
     1861 aagtaaagag cacggttcat ttgcctaaag aaggtgttta tgtgtcggaa ataaaaattg
     1921 gggaaacatg gtatccagcc atgggttcaa ttggacataa tgatacattc ggtgaaggac
     1981 gggagctgac tgtagagttg tatattttgg actttaatca agatatctat ggtgaacatg
     2041 tcgcggtacg ctggaatcaa tttttaagag atcaagtgaa attttctagt gtagaggaat
     2101 tgattgaaca actcaaggag gatgaacaag caacagctga atatttttct cagcaataaa
     2161 acattatgca taaaatctct tgtttatgta taactagcaa ttacaataaa atgggtgata
     2221 aataagccca ggaaaggggc tgtgacaaaa gtcttgtcac agcctttttt tccaaataaa
     2281 tggtttttca gaagtagctt cttcggaaat aagccgaaat ttcttgaagc tgaccacttc
     2341 tgtcacaacc tctttcttta tagaaataaa aggacactag caattcatga aaacgattgc
     2401 tagagcgtat catttgcttt agactatata tcttggtgta cactcacttt aaggcggaaa
     2461 taaaagttat ccgtaataac aggtttaggt atgaaaaagg agtgggtact atgtacaagg
     2521 aattagaaaa caaagtcgca gtagtaactg gtggctcaaa ggggattgga acagcgattg
     2581 ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa ctataactcg gataaagaag
     2641 gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg aaaagcagtc tctgtacaag
     2701 cagatgtcag ttctgaagaa ggaatacagc gtttacttga tacggcttta gaaaattttg
     2761 ggacactgga cgtttgggtt aataatgctg ggatggaaaa tcagcatcca acccatgaac
     2821 ttagccttga agattgggaa agagtgttaa aagtcaattt gactggcgtt tttatcggaa
     2881 cgaaagcggc tttaaattac tttacagaga ataataaaaa aggaaatatc atcaatatgt
     2941 cttctgttca tgaacagatc ccatggccaa cgtttgctca ttacgctgct tcaaaaggcg
     3001 gggtaaaatt atttaccgaa acggtagcaa tggagtatgc accgaaggga atcagaatca
     3061 atagtatagg ccctggtgct atccgtacac ctattaatgc ggcaaaattt gatgatcctg
     3121 aacaaaaaga actcttggaa agtatgatcc cactaggacg cgtaggtgaa ccaaaagaaa
     3181 tagcggcgac agctgcatgg ttggcttcag acgaatccag ttatgttaca ggtattacac
     3241 tatttgcaga tggtgggatg actttatatc cttctttcca aggtggaaaa ggataagggt
     3301 gaataaaaat gggtttattg attgcattga tcccggcagt tggctggggg atccagccac
     3361 tgattttgaa aaagattggt ggcagaccaa caaatgagat attaggaact ggtattggag
     3421 cggtgcttgt cggcttactc gttcaattat tcgcttctcc agctggtatt tcagtgacta
     3481 catttttgat tagtttactt tctggtgcat tttgggttat tggacaaaca ggacagtata
     3541 catctttcaa cttgattggt gtttctaaaa cgatgccaat ttcgactgca ttacagttag
     3601 tcggaacctc gttgattggt gtcttcgctt ttggagaatg gtctggaagt atggggaaaa
     3661 tcattggagc agcagcaatc attcttcttg tatttggttc tgctttaacg gcaatcagtg
     3721 atgatcctgg aaaaaaaggc ggtatcacaa aaggaattag tctattagca tcaacaagta
     3781 ttggttattg ggtatacagt gcattgccta aactagttga tgcaagcgga ctttccattt
     3841 tctttccgca aatgatcggt gtctttttag gggcagtgat ttatgtgatt ttccgtaaac
     3901 caaccgcatt ttctgaagac aagagttgga aagcaacgat cgttggagcc atctttagtg
     3961 tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg ggttgctact gcatatatca
     4021 ttacacagct aaacgtagtt atctctacat taggcggtat gtacatcctg catgaaaata
     4081 agacaccaaa agaaaaaaaa ttaacgatta tcggattatt gctgatcgta gtaggaagca
     4141 tggtcacggt ctttatttga ggataaagat ggtaaaattt catttattaa aaaaatattt
     4201 gtttgaacca aacagtaagt acttataaaa aaatagcgct agaatttcca acatctatgg
     4261 aatttctagc gctttttaat tgtttaagat acaagggaaa tatctgtctg gatcaataat
     4321 ttttcattga tccattgact aaagtttacg acataattga agttaccacc gattagtatc
     4381 tccgcatgat tgtctttata aagatcgtat tgtaaaagac ggtctttttt atttgcgtaa
     4441 acatcgttat ggtactggac taattgttct cggaattgat tgattgctgt aaaatcacga
     4501 tattgaaggt tgaaacgcat cgtgattggt gcatttagca tgaatcgctg catttctttt
     4561 gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa gattacgttc agaaaatttc
     4621 cattgcccgc caacctttgt tccttttagt tttccttcat gaagataatt tctgatagaa
     4681 cgtgtagtaa cacctaattg ttcggctaat tcatttactg agtaaaaatc tttcaatgtt
     4741 caccctccta tgtgaatggt tctactgact tagttgatat ttgcttaatc acgaaatgta
     4801 gaaagaacga ttttaattaa ggtcattgta aaaatcaagt cagaaaattc taacttttat
     4861 ttctctaaag aaattcgttc tctcctaaag tgatattata tttaaatata cctgaaaata
     4921 atgggcagta ttatgaaaga tcactgatat tttctcgtat tttttcctta ttcaaaagtt
     4981 ttgcaggaaa attgctgaaa aaataatttt actaagtaga aaattcaaag ccattcaatc
     5041 agtgattttt ttcagcacaa gaaagactcc ttataaaaat agcagatact ttgtcaatta
     5101 agtgtttaac cagggatgat aaaaaggata ggattgaaca aaacctgtat aaggtgatga
     5161 atagtttcct cgccagtaaa aggtttattc gtataaagct ttatcgccaa aatttatcat
     5221 gacctttttt atcttcaata ttaaatgaaa tcaattgttc aatcaattcc cagttgatta
     5281 cacttttcca aggaactttg atgacgttat ccgtatatac gtagcctgct tcttggatat
     5341 ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat agaaaaatga tttttagcaa
     5401 aactaaatgc aataataaag gtaccatggt cagtaaacat aggttggttc cattttacag
     5461 ttgtgtctag ctggggatac gtttctgtta tcttagcaaa aaggtctttg atcttttgtt
     5521 gatgttcttt ttctttgatt tgattgatga tcggctgaaa tttttccatt ctaaaacgcc
     5581 tccattaagt ggtttgattt attttaccag aaaaacaata gttatgtata aaaaacgaac
     5641 aaaacacaag taatgttgta accgctatat ttatatgata agatgtctca aataataaaa
     5701 tagaaaagag acataaaaat gattgacttg gcaaagaaat tcttacacga aaatatatat
     5761 tttgagttgt atcatcatcg agccatttat acaaatgaag atgctttggt aataaagaaa
     5821 gaacaaggat ttacaggtac agagaccaaa agcttattct taaaagataa aaaagataat
     5881 aactacgtat atctgacttt tactacgaaa caaacggatt tcaaagcatt agggaagatc
     5941 gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg aagaacaaac gggacaaaag
     6001 cagggcgctg tttctccgtt tggttatgaa aaacagattc cgattattat tgatgaagag
     6061 ctcttatcaa atgaaaaact tgtttttgca ccaggtagac cagatcaaac gatggtcatc
     6121 caaacggttg acttaaacaa aatcatccag ctacttgaga tgccgatatt tttgatgccg
     6181 gcaaacgaaa aaaacaatta accaagtaaa atagtgcata cttggaggtg aagcaacatg
     6241 ataagttatc cattattaga aagaaatgca acgattgggg ttactgcacc atcctcaggc
     6301 gtatcagagg aacaccattc gttactcgaa tcagctttaa agagaatgga agaaaaatct
     6361 ttccaagtag ttactggaaa gacgctttgg acgcaagata aggaaaaatc aggtccagca
     6421 agaaaacgag cagatgaatt caatcaaatg atgcaagatg aaaatatcca aatgatcttt
     6481 ccgacttggg gaggagaatt attgattgag attctcgatt ttgtcgattt tgatgctcta
     6541 caaccaaaat ggatagtagg ttattcagat attagtacgt tgctacttgc tgtcacatta
     6601 aaaacaggga tagccactgc acatggaact aaccttattg atttaagagg agagtacttg
     6661 gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa gagaaggaga atcgattcta
     6721 cagcaatctt ctgaaaagta tcaaaaagtg tggccccatg agcattcatc atcttctgtt
     6781 ttccatctca ctgaaccaac aaattggcaa tcagtcagcg gagatgcagt aaggatgaag
     6841 ggacgattat taggtggttg tattgatacg atcaggcatt taatcggtac tccttatgga
     6901 gatgtccaat cttttaaaag aaagtataat gatggaaagc cgatcttgtg gtttctagaa
     6961 aactgtgagc tatcgtcagt tgatttaaga agatcacttg ttcagatgaa actggcaggc
     7021 tggtttgatg gcagctcggg gatcatgttc ggtagaagtg cggcagagga tttgttagat
     7081 tataaaatga aggatgtata cgaagatctg tcaaaggaat taaaactacc gatcttgtat
     7141 gatattgatt gtggtcatgt accgccacaa ctgacattga ttaatggtgc ctatgcagaa
     7201 gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt ttatttaaaa aattttttcc
     7261 tgccttggag tctatcaaag accaataaat ctaaatagaa aagaaagtga aagaagctga
     7321 caaaatgctg tcagcttctt tttgtataac atattagaaa gtctaattat ctataactgt
     7381 cacatcgatt aa
//
LOCUS       DAFEML010000095         7085 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFEML010000095
VERSION     DAFEML010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.098"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            127..579
                     /locus_tag="LP468_002489"
     CDS             127..579
                     /locus_tag="LP468_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081972.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="LP468_002490"
     CDS             593..1282
                     /locus_tag="LP468_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081973.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="LP468_002491"
     CDS             1407..3758
                     /locus_tag="LP468_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL2081974.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="LP468_002492"
     CDS             3838..4233
                     /locus_tag="LP468_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081975.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="LP468_002493"
     CDS             4558..5175
                     /locus_tag="LP468_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2081976.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="LP468_002494"
     CDS             5216..5515
                     /locus_tag="LP468_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL2081977.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="LP468_002495"
     CDS             5549..5716
                     /locus_tag="LP468_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2081978.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6282)
                     /locus_tag="LP468_002496"
                     /pseudo
     CDS             complement(5761..6282)
                     /locus_tag="LP468_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(6333..7013)
                     /locus_tag="LP468_002497"
     CDS             complement(6333..7013)
                     /locus_tag="LP468_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HBL2081979.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2381 a         1035 c         1389 g         2280 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattgg ttctgttgcg aagtttgaaa
     6301 atcaaacgcg ccctctctga actccaaata tcttaggctg ttattcccat taataccttg
     6361 atttcagtag acaccgaaaa gccgaagagc gttccatttc ttcggttctt tttatatatt
     6421 cctcgaatgg tctccatgcc cttaatcgtg gaagaggctg tacggagact ttgataaaat
     6481 ttatttcgtc gtttaatagg tcgatggtct tgttctatta aattgttaag atacttcaca
     6541 gttcggtgct ctgtcttagt atataaaccc acactctgta actttctaaa ggcggagcca
     6601 agagaaggtg ctttatcggt cacaattgct ttcggctcac caaactgttt atggagtcgt
     6661 tttaagaaag cataggctgc ttgcgtatcc cgtttctttc gtaaccagat atctaaggtt
     6721 aagccgtccg catcaattgc acgataaaga taatgccaac gtcccttaat tttgatatag
     6781 gtttcgtcca ttttccatga atagaaggat tgtctatttt tcttcttcca aagataatag
     6841 aggactttgc tgtactcttg cacccaacga taaatcgtag tatgacaaac atttattcca
     6901 cgatcatata acaattcctg aacttcacga tagcttagat tgtaacgcag gtagtaacca
     6961 acagcgacaa taatgacgtc ttttttgaat tgtttgcctt taaaatgatt cattactctg
     7021 tcctctctgt cttttttctc aattttacac taaaatagat tttttggaaa actttgcaac
     7081 agaac
//
LOCUS       DAFEML010000096         6914 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFEML010000096
VERSION     DAFEML010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.099"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(361..1479)
                     /locus_tag="LP468_002498"
     CDS             complement(361..1479)
                     /locus_tag="LP468_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081980.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1950..3257
                     /locus_tag="LP468_002499"
     CDS             1950..3257
                     /locus_tag="LP468_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL2081981.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3376..4575
                     /locus_tag="LP468_002500"
     CDS             3376..4575
                     /locus_tag="LP468_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2081982.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4602..5870)
                     /locus_tag="LP468_002501"
     CDS             complement(4602..5870)
                     /locus_tag="LP468_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL2081983.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6033..6679)
                     /locus_tag="LP468_002502"
                     /pseudo
     CDS             complement(6033..6679)
                     /locus_tag="LP468_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
BASE COUNT         2098 a         1446 c         1225 g         2145 t
ORIGIN      
        1 acggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa
       61 taatttttgt caatctcttc ttatttcttg aagctgacca cttctgtcac aacctcttcc
      121 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa
      181 gagctatttt tgcttgctgt tcttattact tgatgcagaa cagctttttc acaacctctc
      241 atacacggtg tttaatcagc tgaccttcgg tattagctca aaaaacggaa aaatatgtga
      301 aactattttt ccgtttgttt ctctaatact caggtcaaaa cactgatttc acaacctctt
      361 ttaataacga agaatcgctg tcagactctt ttcatctggc gcatcttttt gatccaaaat
      421 aaacactttc ccgccattaa tgatcacatc atctgctaat gcattcaaca cttgacgccg
      481 atcatattct gtttcaggat cttcaccgaa accatcagct aagtttgacg tagcgataaa
      541 taaatgtgac acttttcctt ctttcgcagc tggaacgata tcaactaact gatcgatgaa
      601 tttcttatct aagagtttat tgtattcttt tgattcttga gctgcgagtt cacttgacag
      661 cttcttcgcc ccttcttcga tatctctaaa ggatagctgc gcaggagaag cagaaatcgc
      721 aacgtctgca caataatagg gatttttagc aatttttttg aacatcgtct gattttctgg
      781 taatgcaaat aaataaatcg gccattgttc aggattttcg aaagaatcct tcaagtacgt
      841 atcaacagct tggtaatagt tgacccaatc gatctctact tcttcatctt ttggatttac
      901 gccatggaaa gttactccat ctcgggctcc gcctcctcca ttagaagaga agttcaaacc
      961 gccacctgtc agttcagatc ccaatgcagt aacgacatca accggtgccc cttctggtag
     1021 agatacttct tttacttgtt tgttgctgac ctcatacaat ttcatggagt cgcggttcaa
     1081 tcccaataaa taataagaat agttgaactg cccatttttg ataatagcca gtaaataagg
     1141 aagatcactt acatagtatt gatcgtctac cgggatactc aaacgatgga tataggtctg
     1201 gtcagcagtt ataatgaccg ctacactcgt agttgcacta cgccaaaacg aaggatctcc
     1261 taacaaattt tcaatttttt cttggaacgg ggaccagtca tgttcggaat attttttctc
     1321 aaaacgtttc tttgcttctt tcgcaaaatt tttgaatttg atctgatctt tttccacatc
     1381 ttgatgggcg acatgcgtat tcagcatgat cgtgacgaat ggtcctttag cgccttctga
     1441 agtcaattgt gtcaataatt ctttatcctt ttttgccata aacgtacccc tcctaaaaaa
     1501 atcattcctt tgtttctatc taaagtctac cacaacacta tttttccata caataaaacg
     1561 tatctaaaaa aataaaacgg tttctacggt tttaaattta gctatttttt taagttatct
     1621 tcataatttc ctcaattatt tagccccagt cttcaactat tcttcatgaa atgctgataa
     1681 actaagaaaa agaataaaag aggtggatct tatgcatttg attatgattt tcagtttatt
     1741 aagtattatc agtttatttg ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc
     1801 tattcctgta aaagtacgta aaaacgaccg ctaaacttcc ataacgcgcg ttcttatcct
     1861 aaagtttttt cagaaacatt gaaactctct cccctctctg ataaaatttt aatttgtagc
     1921 gaaacaaatt aattacaagg agatcggata tgtccataaa aaaaacacgt ctagtcctat
     1981 tattggctag tctcattctt tgccttgctt cttttctacc agctgttgct gtgcaagctg
     2041 aagatacgtt caaagtaaat gcaaaagcag cttttgctgt agatgcgcaa agcggtaaga
     2101 ttctttatga tcaagatgga gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg
     2161 gtctttacat cgtccttgat caagtaaaag aaggaaaact gtcatggggt gataaagttt
     2221 cgatttcaga ttatgcagaa aatttgagta tcaccccaga tttatcgaat gttcctttgc
     2281 ataaagaaaa cacctacact gtcaaagaat tattcgactc tgcaatcatc cagtcagcca
     2341 atgcttcaat ggtggccttg gcagaaaaaa tctctggcag cgaagctaaa ttcactgaac
     2401 gaatgaaaga acaattgaaa gattggggaa tcaaagatgc aacaatcgtt aatgcatcag
     2461 gattgaacaa ctcttatctt ggcgaaaacc gaccagaagg cactggagaa aacgacgaaa
     2521 atcaaatgtc tgctcaagat gtggccatcg ttgcccgcca tttgatcttg gatttcccag
     2581 aaatactgga tgtatcaagt actacgaccc aaatgtttgg cgaaaatacg caatcaccag
     2641 tggaaatggt caactggaac tggatgctcc caggattcgt taattacaag gaaggcgtgg
     2701 acggattaaa aactggtacg actgagcttg caggtgcttg tttcgttggt acgatcacta
     2761 aaaacgatca acggatcatc actgtcgtat tgaatgcgga cggccatgcg gaaaacccga
     2821 gtgcccgctt caatgaaaca gaccgtttga tggactactg ctatgacaat tggtcagaaa
     2881 aagagctcgg aaaagctaac gcaagtattc ctagtctaaa aaccattgat gtaaaagacg
     2941 gaaaagaatc aacagttcct gttgtgctta aaagccctgt aaaagtatgg gtacgaaacg
     3001 atatggatac tggcaaatta acgatcacgc caacacttga caagaagcaa gtcactgaca
     3061 atgagatcca agcacctatg gataaaggta caaaaatcgg taccgctacg atcaccttgg
     3121 cagacgataa attaggctat ttagaagaca acaatgcacc atcaacagag atcattacgg
     3181 ataaaacagt ggaaaaagcg aatatattcg tgattggctg gcgacgcgtc gcagaatttt
     3241 tcggcaactt gttttaattg aacaataaga aaaacatctt tccatcggaa agatgttttt
     3301 ttgctttttc tagtttaaat aacagctttt ttcatctatt ttcgttatac tgtataagaa
     3361 aaaggagttg aatttatgaa tctaaccaga gatctgatct ttttagttct ctatcttatt
     3421 ggggtattct ctatcgttta ttggcgaaaa cagaagaagg atccttcctt gttcttttac
     3481 ggcagtacgt ggacatttac ggtaatctta acttattttg tcgtgttgga aattttttat
     3541 tcgacctttt attttttgat tccattgttg ttctttagta tctttgcttt ttcttatttc
     3601 acagaaaaac gaaggctact gaatggtctt ttattcaatg ttttactcat cagtttcggc
     3661 atctacttgt ttgtcttgct gtatgaaacg caaaatattt ttcttggcgg actgatcgcc
     3721 ttgatcacga ttccattgct acttgtcctt ttatttggta tttatggatt gattgttttt
     3781 cttttttgga acggggtcac agttttacgt agagaatcgc attcattagc taatctttta
     3841 acgttgatac tagccatttt tcttacactg tttcttgttt ttgacttttt cttgttaaaa
     3901 tatttgccgc aatggataaa tgctttgttt ttctgcgttc ccctgatctt gatctatcta
     3961 tttatcgtat tctacaactt tttgactgtc tcattcttgt atcagttcaa ccggcctcga
     4021 tacaatcaag acttcatcgt tgtgttaggc gctggattga tcaatggaga aacagtttct
     4081 cctcttctag ccaagcgaat caataaggca attgcttttt atcgggctca aagccgtgct
     4141 acattaaatc cgcccatctt attgatgtct ggcgggcaag gagcagacga aaaagtacca
     4201 gaggccattg cgatgaaaca atatgccatg gaacaaggaa tccctgaaag agacattctt
     4261 gtcgaaacca attcgacaac cactttggaa aacatgctct attcaaagga aatcatggat
     4321 cagcaaatga aagggccata ccgcgcgatc tttagttcca acaattacca catttttaga
     4381 gccggtcttt atgcgcggca agccaaattg aaagcaaatg gtattggtgc aaaaacagct
     4441 ttctactact tgcctaatgc gtttttaaga gaatacctcg ccatcttgat gatgaacaaa
     4501 aaaagacata tgatcatttg cggattgctt ttcgcaggct ccgcattctt atcgctgatt
     4561 actttacttt tctaaaaaaa caaggtgtga caaaacatat gtcacacctt gtttttttct
     4621 ttcattctct taactattgg caaaaagagt atcccttttt tgaccgctac ttgctgagca
     4681 gaataaatac cgctgttgcc tgaacacata aagctgatca agcagatcat aaagaagtat
     4741 actgccgctt gtgaaccgaa caattcgatc cccatcacaa agcaggcaat cggtgtattt
     4801 gtcgcaccag aaaatactcc gataaagccc aatcctgcaa gaaaaggaac agaaacatgg
     4861 agcaaaggcg ctagtgctgc accaagcgtt gcaccaattt caaacaatgg tgtcacttct
     4921 cccccttgat atcccgcgcc taaagacaaa actgtgaaga ataacttccc aataaaatca
     4981 tagacatgtg cctgtccatt aaatgattct tgaagtaacg gaagactcaa tccgagataa
     5041 cgttgtgttt gcaaaatcaa tgctgctgcc acaactacag ctccacctat cgtatttcga
     5101 caaacaggat gaggaatcca ttgtgcatat cgcgctttta aaaagacgat cgaacggctg
     5161 aatacccaac caatcaaacc aaaagcaatc ccagcaacaa aaactttgaa gaacagcaac
     5221 atactccatt caggaatcac acccatttgg taatgtagat gagaaacacc atagctttct
     5281 gtcatgaaat ttgcaaacag tgcagcaaag aagctaggga agatcgcttc tgttcggact
     5341 ttcccgattg ccaacacttc taatccaaat aatgttccag ctaaaggtgt gccaaataca
     5401 gaactaaaac ccgcactgat tccactgata atcaagattt cccgttctga tttatccaat
     5461 cggaacaaac gtgccgtatt atctgctaac gctcccccca tttggactgc tgttccttca
     5521 cggccaacag atcccccaaa taaatgggta gttatggttc caaacagtgt aagtggaata
     5581 agccgcaacg ggattttttc ttctccacca tttccttgat cgatcactaa gttgtttcca
     5641 cgactagaaa gtccgccgtg atacgcatag agataagcaa aaagcgcacc actaactggt
     5701 agtagacaaa ggagccaagg atgtgatagt cggatatctg tcacaactgt caggctattt
     5761 aagaaaaaag cagacaagct ccccatgaat ataccgagaa tcgctgtgat caccagccac
     5821 ttcagcatat acactaaaat gcgtactgga ctcggtaatt gtttttccat aaaaaattcc
     5881 tcctcaataa aaaaacgcct actaaagaaa ggggctgtcc ccagacttta gtaggcgtca
     5941 ttagctatct ttcgttagca tttaaaggcg aacaccatca cctattcact tccattaaaa
     6001 gatagcatat ttttctgtaa aaaacaataa aattatcgtt ctttctttac acgttcagca
     6061 aattcataga aaggagccaa tttcgttaac tgttgattac attggtcact atcatgacaa
     6121 atataattcc cctttttcgt atacgtgcca tcagaacctg ctttcgttgt agaaagaaaa
     6181 agcgaaacat tcgatgtttt ctgacagatt gcacagattc ccttatttat cgttggtgat
     6241 aaagtaccgc taatcccttt taatttttca tcttcgtaat agaccatgaa ttttttctgc
     6301 gtacctggat cattccagcc gatgtacgta tgttcttgca agtcgatttc attccaagct
     6361 ggttgtttga gttttttcac ttttcggaat aatttctcga tttgtggttt gctaggctgc
     6421 ataaacggct gaacgatttg cttcagctcc tccaatgctc tttctgcttg cgcttttgtc
     6481 agttttacgt ctaaaactgt cgttaaaaat gtatcgattc tggcagttcg tgatctaata
     6541 tgtctcgaat cttttcagct gctagtgcct gaactgtttg taccgttttt ggatcattga
     6601 cagatgagta cgcatttaat aactgttcta cttctcttat tataaaaaaa tattggtatg
     6661 gttttattgt ttgttccatg attttaaagt cctttcttct aaccaaagtg catactttgt
     6721 agaaaaaagt gatcttctgc aaagtatgtg ttacctgaag atcccggact cttttaaata
     6781 agatacgttt tgcatcttat catcaccccc tttaatgctt attattctat gtacatgatt
     6841 cattcgataa ataaaagtaa accgtatctt gaacagatag tcaactgcaa acagaaaaaa
     6901 ggactgtgac aaaa
//
LOCUS       DAFEML010000097         6900 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFEML010000097
VERSION     DAFEML010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.100"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..156)
                     /locus_tag="LP468_002503"
     CDS             complement(<1..156)
                     /locus_tag="LP468_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2081984.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQ"
     gene            302..385
                     /locus_tag="LP468_002504"
     CDS             302..385
                     /locus_tag="LP468_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL2081985.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            510..1247
                     /gene="erm(B)"
                     /locus_tag="LP468_002505"
     CDS             510..1247
                     /gene="erm(B)"
                     /locus_tag="LP468_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2081986.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1417..1677
                     /locus_tag="LP468_002506"
                     /pseudo
     CDS             1417..1677
                     /locus_tag="LP468_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1840..2505
                     /locus_tag="LP468_002507"
                     /pseudo
     CDS             1840..2505
                     /locus_tag="LP468_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2541..2786
                     /locus_tag="LP468_002508"
     CDS             2541..2786
                     /locus_tag="LP468_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2081987.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2889..3758
                     /locus_tag="LP468_002509"
     CDS             2889..3758
                     /locus_tag="LP468_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2081988.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3739..4473
                     /locus_tag="LP468_002510"
     CDS             3739..4473
                     /locus_tag="LP468_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2081989.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4506..5414
                     /locus_tag="LP468_002511"
     CDS             4506..5414
                     /locus_tag="LP468_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBL2081990.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5411..5953
                     /gene="sat4"
                     /locus_tag="LP468_002512"
     CDS             5411..5953
                     /gene="sat4"
                     /locus_tag="LP468_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL2081991.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            6046..6840
                     /locus_tag="LP468_002513"
                     /note="aph(3')-IIIa"
     CDS             6046..6840
                     /locus_tag="LP468_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2081992.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2410 a         1053 c         1424 g         2013 t
ORIGIN      
        1 ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg ccacgatcat ataagatttc
       61 ttgaacttca cgatagctaa ggttataacg aagatagtag cccacggcta caataatcac
      121 atcctgctga aattgctttc ctttaaaatg attcatcgtc attcctcctg ctatcttttt
      181 ctattattct accttatttg atagtagatt taaaactttg caacagaacc attttgtgta
      241 taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg agggattcgt
      301 catgttggta ttccaaatgc gtaatgtaga taaaacatct actgttttga aacagactaa
      361 aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt gactaatctt
      421 atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct gtatttattt
      481 acagatgtaa taacttcagg agtgattaca tgaacaaaaa tataaaatat tctcaaaact
      541 ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta aaagaaaccg
      601 ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg gctaaaataa
      661 gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg tcagaaaaat
      721 taaaactgaa cattcgtgtc actttaattc accaagatat tctacagttt caattcccta
      781 acaaacagag gtataaaatt gttgggagta ttccttacca tttaagcaca caaattatta
      841 aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa gaaggattct
      901 acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact caagtctcga
      961 ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa gtaaacagtg
     1021 tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg aagctatata
     1081 cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact aaaaatcagt
     1141 ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact tatgagcaag
     1201 tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc tatgagtcgc
     1261 ttttttaaat ttggaaagtt acacgttact aaagggaatg gagataaatt attagatata
     1321 ctactgacag cttccaagaa gctaaagagg tccctagcgc ctacggggaa tttgtatcga
     1381 taaggggtac aaattcccac taagcgctcg ggaccccttg taggaaaatg tcctaagtgt
     1441 ggcaacaata ttgtattaaa aaaatcgttt tatggttgtt caaattatcc tgaatgtaag
     1501 tttactttag ctgaacattt tagaaagaaa aaactaacca aaacgaatgt aaaagaatta
     1561 ctggagggaa aagaaaccct ggtaaaagga atcaaaaaca aagagaaaaa gccctacaat
     1621 gccgttgtaa aaattgggga aaagggatat attgatttta tctctttttc aaaataaaca
     1681 tggggctgac ccaaaagtag ctcctatatg aaaaatagag gtctttccat ttagatagta
     1741 gtggaaagac ctctatttat cttttgaaag tgaatacaaa aataaagcac actctgctat
     1801 aatataggtg attaatccat ttgagagagg tgctttatca tgtatcaaaa ttataccata
     1861 aaccaacttt gtttgcctat agatcttgaa attaaattag aagaaaatga ttttgctcat
     1921 gccattgtgc agtttgttga ctctattccc gatgaagtct ttcttcctta ttatcaatct
     1981 atgggtagac cccaatatca tcctcgtatg ctactttcca ttattctttg tgcctatatt
     2041 caaggggttt attcgggccg ccaaatacaa aatatgctga tagatagtat tcggatgcgc
     2101 tacttatctc aagagcaatt ccctaacttt cgtactatta atcgttttcg cgttcatccg
     2161 attatgaacg atattctaga tcattcattt gttcaatttc gtgagctact ggttcaaagt
     2221 ggcttaatca gtggcagtgc tctatacatt gatggtacaa aaattgaagc ggatgcgaat
     2281 aaatactctt tcgtttggaa aaaaagtatt ttaaagtata aggatagcct tgatcaaaaa
     2341 gcccttgaaa actaccaaca aatggtggaa acaaaaatct tacctgagtt aatagatgat
     2401 ttaaaggatg aactttctat agaagagatt gaaaggattc gtcaatcttt ggaagaaaag
     2461 gaaaatcaat taattgaagc gattgaccaa accgaaacag tagaaggggg ctgacccatt
     2521 attaataagg agtggacaac atgattgatg taaatgagct attggaagaa gctattagag
     2581 aaactgaaaa tctaaatgat ggcgaagttt ttcttgttaa agatttattc aagggatatg
     2641 tggggaatag gatacccaga aaggatcgac ttctgcttgg aacgttattt ttaaaccatg
     2701 ttagcaaaat gaatggtaat ttaaaggcta ttgaaaagac ttcatctaat cagcagaggt
     2761 ataaaaagac aattgataag ttttaactat cttttgtgaa attaaaaaaa ttataaatat
     2821 gttgagtaga agcaaaagat ttggcttgga atttttacag cagtgaatcg ataaaaggag
     2881 catgcttgat ggtagataat attattaaat cagtagcaga gaaattatcc tctctgtctt
     2941 atatagaagg tattgtttta ggtggttcac gtgcaagggg cacccataca gaggattcgg
     3001 atatagatat cggcatctat tacaattcag aatcatttga cataaatact attaatcaat
     3061 tcgctacaaa gctggatgat gagcatagaa ataaccttgt tgtacctccc ggagcatggg
     3121 gtgattggat taatggcggc ggatggttag tcataaacgg gtatcatgtg gatttaattt
     3181 tacgtgatat taaacgtgtg gaacaaataa tgaaagatac agagcacgga attgttactg
     3241 ccaattatca gactgggcat ccccatggtt atattagtgc aatgtatcga ggagaattag
     3301 cgattagcaa aatactatat gctaagaatg aaagcttatg cgaattaaaa aaacaggcag
     3361 aaacttatcc caatgctttg cagaaaagtt tagttaactt ttttatgttt gaagcagggt
     3421 tctctttaat gtttgtaaaa gcaaattcgg gaacagacga taaatattat attgcgggtc
     3481 atgtttttcg tatagtttca tgtttaaatc aagtgttatt tgcatgtaat aatgcttatt
     3541 gtatcaacga aaagaaagct ataaaactgc ttgaaacttt tgaacataaa cctgaaaaat
     3601 ataccgagaa ggtaaatcat atttttgaag tactcggtat ctcacttttt gaatgctacg
     3661 acatgaccga gaagctttat aatgaagtga atgaaattgt atcggagata aataactttt
     3721 taaacgagga gagttcagat gaaagaaaac aaatatgatg ataatatatt ttttcaaaaa
     3781 tacagtcaaa tgagtcgctc gcagaaagga ctggctggtg cgggagaatg ggagactttg
     3841 aaaaagatgc tacctgattt taagggtaag cgtgtgcttg atttaggatg cggctatgga
     3901 tggcactgta tatatgcgat ggaaaacggt gcttcctctg tagtaggtgt tgatatttct
     3961 cataaaatgc tcgaagtagc aaaaggaaaa acccattttc cacagattga atatgaatgc
     4021 tgtgccatag aagatgtgga tttcccagag gagagctttg atgtaatact aagttcgctt
     4081 gcgtttcatt atgtagcaga ctatgagaat ttaataaaaa agatatatag gatgctgaag
     4141 gctggtggca atttagtttt tacagttgaa catcctgttt ttactgctca tggaacacaa
     4201 gactggtatt ataacgaaaa aggagaaata ctgcatttcc cggtggacaa ttattattat
     4261 gagggcaaac ggacagctat gtttttggaa gaaaaggtta caaaatatca tagaacactg
     4321 accacatatc taaatacact gctttcaaat agttttataa taaatcagat tgtggagcca
     4381 cagccgccag agaacatgat ggatattccg gggatggcgg atgaaatgcg acgcccaatg
     4441 atgctgattg tatcggcaaa aaagaagatg taataatata gaaaaaataa acgaggagta
     4501 tgtaaatgag atcagaaaaa gaaatgatgg atttagtact ttctttagca gaacaggatg
     4561 aacgtattcg aattgtgacc cttgaggggt cacgcgcaaa tattaatata cctaaagatg
     4621 aatttcagga ttatgatatt acatattttg taagtgatat agaaccgttt atatctaatg
     4681 atgactggct taatcaattt gggaatataa taatgatgca aaagccggag gatatggaat
     4741 tattcccacc tgaagaaaag ggattttcct atcttatgct atttgatgat tacaataaaa
     4801 ttgatcttac cttattgccc ttggaagagt tagataatta cctaaagggc gataaattaa
     4861 taaaggttct aattgataaa gattgtagaa ttaaaaggga catagttccg actgatatag
     4921 attatcatgt aagaaagcca agcgcaaggg agtatgatga ttgctgcaat gaattttgga
     4981 atgtaacacc ttatgttatt aaaggattgt gccgtaagga aattttattt gctattgatc
     5041 attttaatca gattgttcgc catgagctgc tgagaatgat atcatggaag gtcggcatcg
     5101 aaacaggctt taaattaagt gtaggcaaga actataagtt tattgaaagg tatatatccg
     5161 aggatttgtg ggagaaactt ttgtccacct accggatgga ttcctatgaa aacatatggg
     5221 aagcattatt tctatgccat caattgttca gggcggtatc cggtgaggtg gcggaaaggc
     5281 ttcattatgc ctatccggag tatgatagga atataacaaa atataccagg gacatgtata
     5341 aaaaatacac tggtaaaacc ggctgcctgg atagcacata tgccgctgat atagaagaga
     5401 ggcgggaaca gtgattacag aaatgaaagc agggcacctg aaagatatcg ataaacccag
     5461 cgaaccattt gaggtgatag gtaagattat accgaggtat gaaaacgaga attggacctt
     5521 tacagaatta ctctatgaag cgccatattt aaaaagctac caagacgaag aggatgaaga
     5581 ggatgaggag gcagattgcc ttgaatatat tgacaatact gataagataa tatatcttta
     5641 ctaccaagac gataaatgcg tcggaaaagt taaactgcga aaaaattgga accggtacgc
     5701 ttatatagaa gatatcgccg tatgtaagga tttcaggggg caaggcatag gcagcgcgct
     5761 tatcaatata tctatagaat gggcaaagca taaaaacttg catggactaa tgcttgaaac
     5821 ccaggacaat aaccttatag cttgtaaatt ctatcataat tgtggtttca aaatcggctc
     5881 cgtcgatact atgttatacg ccaactttga aaacaacttt gaaaaagctg ttttctggta
     5941 tttaaggttt tagaatgcaa ggaacagtga attggagttc gtcttgttat aattagcttc
     6001 ttggggtatc tttaaatact gtagaaaaga ggaaggaaat aataaatggc taaaatgaga
     6061 atatcaccgg aattgaaaaa actgatcgaa aaataccgct gcgtaaaaga tacggaagga
     6121 atgtctcctg ctaaggtata taagctggtg ggagaaaatg aaaacctata tttaaaaatg
     6181 acggacagcc ggtataaagg gaccacctat gatgtggaac gggaaaagga catgatgcta
     6241 tggctggaag gaaagctgcc tgttccaaag gtcctgcact ttgaacggca tgatggctgg
     6301 agcaatctgc tcatgagtga ggccgatggc gtcctttgct cggaagagta tgaagatgaa
     6361 caaagccctg aaaagattat cgagctgtat gcggagtgca tcaggctctt tcactccatc
     6421 gacatatcgg attgtcccta tacgaatagc ttagacagcc gattagccga attggattac
     6481 ttactgaata acgatctggc cgatgtggat tgcgaaaact gggaagaaga cactccattt
     6541 aaagatccgc gcgagctgta tgatttttta aagacggaaa agcccgaaga ggaacttgtc
     6601 ttttcccacg gcgacctggg agacagcaac atctttgtga aagatggcaa agtaagtggc
     6661 tttattgatc ttgggagaag cggcagggcg gacaagtggt atgacattgc cttctgcgtc
     6721 cggtcgatca gggaggatat cggggaagaa cagtatgtcg agctattttt tgacttactg
     6781 gggatcaagc ctgattggga gaaaataaaa tattatattt tactggatga attgttttag
     6841 tacctagatt tagatgtcta aaaagcttta actacaagct ttttagacat ctaatctttt
//
LOCUS       DAFEML010000098         6644 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFEML010000098
VERSION     DAFEML010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.101"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP468_002514"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP468_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP468_002515"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP468_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL2081993.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP468_002516"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP468_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="LP468_002517"
     CDS             complement(2603..3421)
                     /locus_tag="LP468_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2081994.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP468_002518"
     CDS             3582..4271
                     /locus_tag="LP468_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2081995.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP468_002519"
     CDS             4285..5787
                     /locus_tag="LP468_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2081996.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP468_002520"
     CDS             5800..6276
                     /locus_tag="LP468_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2081997.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LP468_002521"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LP468_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAFEML010000099         6622 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFEML010000099
VERSION     DAFEML010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.102"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            138..2813
                     /locus_tag="LP468_002522"
     CDS             138..2813
                     /locus_tag="LP468_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBL2081998.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2995..3234
                     /locus_tag="LP468_002523"
     CDS             2995..3234
                     /locus_tag="LP468_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2081999.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3250..4623
                     /locus_tag="LP468_002524"
     CDS             3250..4623
                     /locus_tag="LP468_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2082000.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4627..6261
                     /locus_tag="LP468_002525"
     CDS             4627..6261
                     /locus_tag="LP468_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2082001.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6424..>6622
                     /locus_tag="LP468_002526"
     CDS             6424..>6622
                     /locus_tag="LP468_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082002.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2321 a         1070 c         1330 g         1901 t
ORIGIN      
        1 caaaatcaca acttttttct tttgtcaaga ttttgagtgg gatatatttt tgtagaactg
       61 aagatcatga aattatgaga ggttggaggt aatgtagtca tacaaataaa aattttttag
      121 aaagtgagtg gtaattaatg aaaatgaatc acacttcaat tcagaagcat ttacaactgt
      181 taaatacact ggggatttct tatgttaatt tgagaacttt ttctacatta aacaagaaaa
      241 ccgtttctca tattttttct actgcagatt ctcaagcaat tattaactat ttagaaaaac
      301 agaaattgtc tgaaggtaca gtaaacataa cttataatcc tattaaacaa gaggtgatta
      361 cacaaaaaaa gcattctgtg agagacaatg atattgaaaa aattcggttt gtatttattg
      421 atattgaccc taaaaggaaa gagggaagtg caacagatag cgaaaagaaa aaggcagaaa
      481 atgttatgga acaagtagaa cgttatttga aagaaaagag aatagaatca tttgtaaaag
      541 ttgatagtgg gaatggctac catatttttc ttcccataaa tgaacaacca aataatcacg
      601 agacgattct tactattcag aattttcttc aattacttca ccgaagattt ggagtagaag
      661 atgaagttga tattgatact tctgtttata atccttcaag attatgcaaa ttagttggta
      721 caccagcggt caaaggaaag tccacaaaag agcgtccgca tcgtttatct agtttccttt
      781 ctattcccga taacatagat agaagtaatt gttttaaaat tcttgaacag atagttgaag
      841 aaaattccat gatgtcaacc tctagagtaa aaagccatcc atcttttaga gaagtgttac
      901 cttttattca agcagactat aaacaatggt tagctcacta tcctgaatta acttatacca
      961 taaaagaggg cgatcataaa ggagttacct tacttatatt tgacgaatgt ccattaagaa
     1021 aacacacgaa taattctaat ggttcttgtt tgtctgttac ggctgataat aagattcgat
     1081 ttcattgtct gcatgcttcg gataaaaata aagatattca agactttgta aaaaaatatc
     1141 cgttgccaaa acctgtaaat ccttctgtag aatcattaga atccaatcaa gaatattatt
     1201 ttgaccagtt taaactgaat caagaaggag tatttttggt gaaagaaggt caagaagaaa
     1261 aagttgcttg tccgatgttt attaagcaaa tacgcaaaaa tatcgaacaa aaagtcatta
     1321 cacttgttct tgcctattat gtcgatcatt gttgggatga aatagaaata gaaggtggat
     1381 gtttacaaac taataatttt aaacaattag caaaacatgg cttaatcatt aaagctagaa
     1441 gagaagctga agtcgttgac tttttacaga ttcaacggga gaatgctcca atcttttttg
     1501 aacatgaatc tcttggctgg aaaaaagaaa atgaagcaat gatttttcag ttacaagatt
     1561 cttttggacg tgaaattcct tctgtattaa ctaaaaactc atgctaccaa ttaacaacta
     1621 atggtacaga agcggaattt gacgcattgg ttcataagta tgttttagga acgaacttag
     1681 aacttgcttg gtcgattggt attgcttcta ttgtgttagg ctatttaaac gttacgaagg
     1741 ctaatacttt tttgagttta ctaattaacc tacagggcaa gagcacaacg ggtaaaacca
     1801 ctacgttaca ctttattgcc tctttatttg gaaatccaac tacggttctt agaaatatga
     1861 atgctaccaa taaagccatt ataaagctag catcaaacaa tcagggaggt gttccactaa
     1921 tactagatga gttaggagca gcaactcaaa ataactttag ctcgttgatc tatcaattag
     1981 cttcaggaga agaaaggcta agattagatt ctaattgtca gcttatgcca caagagactt
     2041 tttctgtttt gacccttacc tcttctgaag agcgtttgga aaattatttc aatgagaaat
     2101 taactggttt gaaagttcga tatatcgaat tttctgatat caagtttaca aaggatgcga
     2161 atcacgcaga gaaagttaaa agtctttctt ctaatacttt tggttggggt ataaagttat
     2221 ttcttttgaa actctttgaa caagggatta caaaaattga agcaactttt gtcgaagctc
     2281 aaaaaaaact atgggctgtt ttacctgaac attctttgaa gcaacgcatt ggtaataatc
     2341 tagctttgat ttatagtgga gccctcctaa ttcaagatat actgggctat cctttacgat
     2401 tagagcatat acagacggtg cttattaatt cgtacgaaca gttaattgta gatactagtt
     2461 taggaagtga gcaaacggta tttgaccgag tgaaaacatt gttggtgatg aatagccata
     2521 aatttttaac aaacagtgac aacaaacata cgcccagtac gatttgggga aaagtatcaa
     2581 ttcaaaaaaa tggggatatt aaggtaaata tttttcctat cccgtttgag gacttgttaa
     2641 ggcgagaatt tcaagtaaag gatctaacct atctttttag gcaattgctt gattcgggta
     2701 atatgtgtgc agaaaaaggg agaagaacga aacgtattca catgaatcgt caagttcttc
     2761 caacatacga gattctatta ccttcttcac tcaaatcgta ttttcgattg taatttagaa
     2821 taaaccaaag tatgaaagtg aggcaccatg ttatggaaat atttcttatt gatttagcaa
     2881 aacaactgat tacttatctg tatgatagcg agcaaaccca aacggaagta aatgaagctt
     2941 gatctatgct tcatttactt cattcaatca aacatgaaag aaaggaaaat tctaatgact
     3001 aaaaataaaa tgacactaaa agcagaggtt cttctgtata ttcaagaaca tttttcaaat
     3061 caagcctttt ttacaaaacc aatttacttg gatttcgaaa taagaggggt atctgctgga
     3121 tctatcgggg gtactcttca agcgttgaag aacgaaggat atttagaaaa tcactttgtg
     3181 caacgttcgt tcaatagaag agtcgtgaaa aaatggtatt tagttcattc atagagaggg
     3241 gaatcaagca tgcgtgtggc ttgttatgat cgaacgtctg tttatgaaga agcgaaaatt
     3301 agtaatgacg ctcaatatga tgcagtgaaa gagtatgttt tagagaaata tgaacaaatt
     3361 ccccaacgat tttcagacaa aggagaatca ggggaaaaag cggagcgtcc agcttttcga
     3421 cagcttagag cttgggtttg tgcgtcagaa gaagaggggg tgatctatgt ttggcgttat
     3481 gatcgattgg cacgtcaagc caaaatagcc ttagaattta ttgagttgtg ccaacaacat
     3541 caggttcaag tgtattcgat ttctgaacct cttcctgctt ctttctcaca cgcgtcaacg
     3601 aataaactat ttgtgcaatt attgttcact tttgcagaac aacaacgaaa cgtcattatt
     3661 gagaatgttc gtgccggact ttcctataaa aagcaacaac ggcaatattt gtcttctgcg
     3721 gtaccatatg ggtatcgttt agtgaatggg aaaatccaac aagaagtaca cgaagcaagg
     3781 attgttcgct atatttttca actttatttg accaaaaaat atggctacaa aaagctttgt
     3841 caacgattga cgcaacaaaa gcttttcttc cgcgaacgtc cttttcagcc ctatcatatt
     3901 tatagtatcc taaaaaatcc attgtactat ggcgaaatca aaggaggatc tttggggaag
     3961 tatctaggaa cctttgaacc gattctctcg aaagcaacct ttttacaagc ccaagagatt
     4021 cgccaatcaa ggtgtacagc taaaaaagat acgtatctgt acttattacg tcaaaaaatt
     4081 cggtgtccct tctgtggtcg tcatctgagt tcgaagtatc aatggaatac aaagaagacg
     4141 aagacgcttc attattatca ttgtaccgac cgaagctgcc aaggaatttt tcttcgggca
     4201 gaaagggttg agtcagaagt attggaaaag atacaggctt tttttcaata cgaaggcgtc
     4261 tatcaagcct tgattgccca attaacgcaa caattagccg aaaagcgaaa agatgaaaaa
     4321 cgcaaagtaa tccaacaaaa gaaacaagaa gcacaatgga ttaaggcatt tgaagagggc
     4381 aattgttcac tggaagaact caagcaacaa ctgcaagctc ttcaaaagcc gatgtctact
     4441 tcttcgtttc tttcactcca acagtgtgaa gcaaaagtga aagaatggct tcaactaaaa
     4501 gacctctcta gtcgacaatt attatgtgac tatgtttgtc ggattgaggt aacaaaggat
     4561 aaaacagttt gtgggattta cttccgacaa ctgacacaaa atattttaga aaggaacgaa
     4621 tgatctatgg aaatgataca aaccaaacga gtcgcattgt atattcgcgt gagtacacaa
     4681 gaacaagctt tagaaggaca tagtattcaa gcacaagaac aaaatggacg acagtttgcc
     4741 gaacggatgg gctatgaagt ggtagaagtt tatgccgatg aaggaatcag tgggaaatcc
     4801 acaaaaaatc ggttcgccta tcaacgaatg atgaacgatg ctcggaacca tcgttttgat
     4861 ctactagtga tttggaaatt gacccgtctc ggacgcaata tgttagatgt cttacaaaca
     4921 gtcgaggaat tattgcgata tgacgtagga ttacattcga tctcggaaca atttgacgtg
     4981 accacttcga caggtaaatt gatgttacaa ctccttggga gtttcggtga atttgaacgc
     5041 aaccaaattg cggagaatgt tcaaatgtca atgcaaagct tagtgaaaga taaaaagcgt
     5101 tatgcaggag gccgacgttt aggctatgtc agtggtattg acacgaatgg tcaaaaacaa
     5161 ttggtcattg aaccagaaga ggcgaaaatt gttcgtctga tctatgcaaa atatttaggc
     5221 ggagcagggt atcgagcgat tgccaatttt ttgaatcgtc aaggatatca aacagtcaaa
     5281 aagaatgctt tttctaccac ggcagtcaaa gatatcttac gcaataaaat ttatgcaggg
     5341 tatttagaat atgcgcgcta catcaattgg gaaaccaaac gacggaaggg gaagaatccg
     5401 agaccgattt tagtgaaagg aacccatgaa ccgattattt cggaagaaga ttatcaaaaa
     5461 gtacaagaac gccttgcttt agaaggaaaa caacccaaat ggaaccatac aggtgaaaat
     5521 gtattgacag gcttgttacg ttgtccagaa tgtggcgcac cgatggcagc gagtaatgtc
     5581 acaaataccc taaaggatgg cacaaagaaa cggattcgat attattcttg ttcagtcttt
     5641 cggaataaag gagcaagtgt gtgtcatgcc aattcgattc gtgccgaaca agcggaaaca
     5701 tttgtcgccg accgattaaa ggagatcgtt cagctaccag aagttcttcc ccgattggtg
     5761 gcagcgttaa atgaagaaat agtgcgacaa agccaaccat tggaacaaga actcgtggtg
     5821 ttactggaac gaaaggaaga attgaagact aaaattgaaa aatgggaagc tgctttggaa
     5881 gatagtcctg aattgtttcc gatgttaaaa gaccgcttag acgaattgac tgaaaaacga
     5941 cgacagttgc acattcgaga aaatgaaatc ttagggatct ttcaacaagg agagccgatt
     6001 caagtcaaag atgtccaacg gatattgact agtttggatc gttttcttgc ccagagtgag
     6061 aagaagcaaa tcaaagcctt gtatcgtacc tttatagaga aaataacctt tgatcctaac
     6121 cataaggaga tgttggaaat tacgatgaaa ttcacgcatg ccgtggtaca acaattgaat
     6181 gagcaatatc aaatagccgt atccaaaaca aaggatacgg ctatttttgt gttaaaaaca
     6241 ccctttacgt taacgatcta gtctaggtta tatcaaacaa cgttagaggg gcgctaacgc
     6301 ttctctagcg atttgaaatc gttagagaag tagttaggga ggtccttatc ataaataggg
     6361 atatttatta atgaatattt gaaatataat tgtatataag aattaaaaag agtggggata
     6421 gatatgaaaa agatgggtaa gtgtatttta tgtgaaaaat acactgaact tactaaagaa
     6481 catgtaccac ctaaaaaatc agggaatact ggaggtaaaa agaccagaac tggtaattta
     6541 gatgatttcc ttaagagcga ttttacaaaa ggtgattttc cgaaggggat taaaaggaaa
     6601 cctcaaggaa atgtttatta ta
//
LOCUS       DAFEML010000100         6586 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFEML010000100
VERSION     DAFEML010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.103"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            63..1574
                     /gene="gadC"
                     /locus_tag="LP468_002527"
     CDS             63..1574
                     /gene="gadC"
                     /locus_tag="LP468_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBL2082003.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            1587..2987
                     /locus_tag="LP468_002528"
     CDS             1587..2987
                     /locus_tag="LP468_002528"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBL2082004.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(3152..4587)
                     /locus_tag="LP468_002529"
                     /pseudo
     CDS             complement(3152..4587)
                     /locus_tag="LP468_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4980..5573
                     /locus_tag="LP468_002530"
     CDS             4980..5573
                     /locus_tag="LP468_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBL2082005.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(5557..6586)
                     /locus_tag="LP468_002531"
                     /pseudo
     CDS             complement(5557..6586)
                     /locus_tag="LP468_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT         2035 a         1108 c         1241 g         2202 t
ORIGIN      
        1 ataagcgatt ttccataacc ttggtaggaa tgacaaatta aataggaaag ggaagtaata
       61 atatgaataa aaaaaagtta tctctattcg gtttttttgc cctgacagct tccatggttt
      121 tgactgttta tgagtatccg acctttgcaa catcacaatt acatttggtt ttctttcttc
      181 ttttgggagg tattttatgg tttctaccag ttgctttatg tgctgcagaa atggcaacag
      241 ttgaaggatg gaaagatggt gggattttca gttgggttag tcaaacttta ggagaacgtt
      301 ttggttttgc agctattttt ttccaatggt ttcaaattac agtaggtttt attacaatga
      361 tctacttcat actaggagcg ctgtcgtatg taattaattt tccagagctt aatacagatc
      421 catttatcaa gtttattggt gtattagtca ttttctgggt actgactttt tcacagttgg
      481 gcgggaccaa tcgtaccgct aaaattgcta aagcaggatt tgtcattgga attgttattc
      541 cttcgatcat tctctttggt ttagcagcag cctactttat cggcggtaat ccgattcaaa
      601 tggctattaa tgcgaaagct tttattcctg acttttctca gctttcaact ttagtagtat
      661 ttgtatcttt tatattggct tatatgggcg tagaagcttc agcatcacat attaatgagc
      721 tggaaaatcc ccaaagaaac tacccattgg caatgttttt actagtgatt ttggccatcg
      781 ccttagatgc aatcggcggt ttctcagtag cagcggttat tccacaacat gacttgtctc
      841 tcagtgctgg tgtaatccaa acatttgaaa cgcttatttt acattttaac agtcatttac
      901 attggttggt aaaagtgatt gctctcatga ttgcctgtgg cgttatgggt gaagttagtt
      961 cttgggtagt tggtccatca cgagggatgt ttgcagctgc tcagcgaggt ctgttaccag
     1021 ttttcttccg gaaaactaat aaacaagacg ttccagttcc gttgattatg atacaaggaa
     1081 ttatcgttac tatttgggca gcagtcttaa cttttggtgg aggaggcaac aatttatcat
     1141 tcttagtagc aatctcctta actgttgtca tttatctcgt aggatattta ctatttttcc
     1201 taggttactt tgtattagtt tttaagaaaa aagacttaaa acgaacttac aatgtaccag
     1261 gaaaaactgt tggcaaaacg attatcggtg gaattggttt tattttatca gtgttcgcat
     1321 tgcttatctc ttttgtacca ccagcttcaa ttgcagctag tgagcaccga acataccaaa
     1381 tcatactact tattagcttt gtagtgactg ttcttttacc ttttatcatt tatgaagtac
     1441 atgataaaag tgctcacaca actattgagg aacctactca cgtgaaagct gaagacgtta
     1501 atcccgctgt ttatccagct gctagaggag agcaccacgt tacaaaaaat gatgaacata
     1561 ttttaaaaca ttaggaggaa ttcattatgt tatacggaaa agataatcaa gaagaaaaaa
     1621 actatttgga accaattttt ggctctgcaa gtgaggatgt tgacttgcct aaatataagt
     1681 taaacaaaga atccattgaa ccacgaattg cttatcaatt agtacaagac gagatgttgg
     1741 atgaaggaaa tgcgcgatta aacttagcta ctttttgtca aacgtatatg gaacctgaag
     1801 cagtgaaatt gatgacccaa acgttagaaa aaaatgcaat tgataaatca gaatacccac
     1861 gaacaacgga aattgaaaac cgctgtgtaa atatgattgc tgatttatgg catgctccaa
     1921 ataatgaaaa attcatggga acttcaacga tcggctcttc agaagcctgc atgctgggtg
     1981 gtatggccat gaaatttgct tggcgtaaac gtgctgaaaa attaggtctt gatattcaag
     2041 caaaaaaacc taacctggtg atctcttctg gttaccaagt ttgttgggaa aaattctgtg
     2101 tatattggga tgtggaactg agagaagtcc caatggatga aaaacatatg tcaattaatc
     2161 tagatactgt catggattat gtggatgagt acacaattgg tattgtaggt attatgggta
     2221 ttacttacac tggtcgttat gatgatatca agggtctgaa tgatttagtt gaagctcaca
     2281 ataaacaaac tgactataaa gtatacattc atgttgacgc tgcatcgggt ggcttttatg
     2341 caccatttac tgaacctgat ctagtttggg attttcaatt gaaaaatgtt atctcaatta
     2401 attcttcagg tcacaaatat ggtttggtat atccaggtgt gggttgggtc ttatggcgtg
     2461 accaacaata cttaccagaa gaattagtat ttaaagttag ttacttaggt ggagaaatgc
     2521 caactatggc tatcaacttc tctcatagtg cagcacaact aattgggcaa tactacaact
     2581 ttgtacgcta tggctttgat ggttatcgtg atattcacca aagaactcat gatgttgctg
     2641 tttatttagc caaagagatc gaaaaaactg gtatttttga aatcattaat gatggatcag
     2701 aattgccagt tgtgtgctat aagctgaaag aagatcccaa tcgcgaatgg acactatatg
     2761 atttatctga tcgtctgtta atgaagggat ggcaagtccc agcctaccca ttacctaaag
     2821 acttggatca attaattatt caacgcttag ttgttcgagc agactttgga atgaacatgg
     2881 ctggtgatta tgtacaagat atgaaccaag caattgaaga gttgaataaa gctcatattg
     2941 tttatcataa aaaacaggat gtgaaaacgt acggctttac tcactaaaat tcttcagaga
     3001 aatataaaag aagttaatta actaataaaa ggagttgtga ttaccacaca gctccttaaa
     3061 tctatttgaa taaatatatg atattcattt gttacactct caatcttagc tgttgttcta
     3121 ttcatcatta ctcttattgt aagtagttca gtcaaatttg cttgttcaat tgatcgataa
     3181 cagtatgaat tgtttgaaaa gtaatcggat atataattgt tttctcacta cctaagcctt
     3241 cttggtataa agaactatcg caaagtataa tccgctgagt acaaaagaaa gtgtcgtcta
     3301 ctatttctct aagttgttta caaatgatat tactaataga aaagtgttct cccaaaatgt
     3361 cttctaactg ttgtcgatag tataaatacc taaagtctga cggagctact atgaacactt
     3421 caattggaga tttccgttta tgctcattta aaagacttaa actaatggtt agtttacgaa
     3481 tagaattctc attccaacgc agaaataaat tgttttgttt tcgccattgt tcaagaattt
     3541 catgaacttc taagtacaaa gcgcgttgct cttcatttaa caagtaagtc ttatcaggtt
     3601 gaaatatctg aatatcagcc caaagtgagc ggataaacgg gagaagtgct ttatcaaaaa
     3661 gtatctgatt ttcttcagat atattcagag ataagataag tttttgactg agctcaatca
     3721 ccaaagggtt atctgctaca tggttttgat aaacaacgtt caagtctttt tgtaacaatt
     3781 caaagttatc gcatagataa tttctagagt tgaatagaaa gtagatataa aggcattcat
     3841 cttcgtcatg acataaagag aaagaaagtt gctctaatcc tttctgtatt agctgaaaca
     3901 agggagtatg tcgggcaact cttttttctt cctgactaaa atatattggg ttagtcttag
     3961 atctctgcaa accgatagcg atacctaata aaataaattg tttttcaact gtagggtaac
     4021 ttcttgaaaa aaatgttttt ctacataatc aatcaattgt tgaccgcttt gaataattga
     4081 tttatttagc tggatcaact ctgtccgatt tgtctcatag attatcgtta gtaacaaact
     4141 tcgataatcc ttttcaggaa tttcaaaatg gccatcagca tttaagtact gcatttgttt
     4201 aaaaaaatta atcaactcat ttcgtaagtt gtaaactttg cttaacgaaa tgaaggtagt
     4261 atcagctata ttactccaat tgtgttcccc tgataaataa tgtcctagta cattgaaaaa
     4321 gtcagagcgc tgatagatga gttgagtgag tgccaacctc gaaaacgaag agtcgaatgc
     4381 gactgtaaag ctacttctag atttctccac tgaaataatt tgctgatgga gtatgtcggt
     4441 aatgcattcc aagtcgttag tgacagtgag tgggcaaacg ttcaattgat ctgctatttc
     4501 gcgaatctga atggtccctt tttcgtgtaa ttgctcacaa atgtaaactt gacgaaaaat
     4561 acttttctcc agataggttt ccaacatagt actcctccta gtcattttat acataactat
     4621 tataactcta ccaatcggaa tagtcctgta atatattgaa tcaaaaatat aaattataaa
     4681 ataattagat ggggtatttg gtttaagtat cccttatata gtaataaatt tataggtgtg
     4741 attctcgaat taatacccga aaatgtgaga gaatttttat ggatttttta ggatacaaat
     4801 taattatttt tgcttttatc ctgattacca gtccagtact gtcggtatcc cattttgcag
     4861 caaaatcatg ttgataaagt gacaagaaga ctgatgagat atattatcca aattgagaag
     4921 ataattaatc ggattcttga gtatacccta ctttttaaga aagtagggta tacaagcgta
     4981 tgaataaaga cataactttc cctgtgatgg acgttcggct tgttccaatt accaaaatac
     5041 aggcgaacga ttataatccc aatcgagtag cgtctccgga aatgaactta ttggagcttt
     5101 ctatcattga agatggcttt actcaaccat tagtttgtta ttacaaggaa aaagaagaga
     5161 agtatatctt ggttgatgtg cttcataggt atcgtgttgc taaggaaaga ctcaacttaa
     5221 aagttgtacc ggtaacagtt attgataaac ccatagaaga acgtatggct tcaacaattc
     5281 gacacaatcg tgcaagaggg acccatgaaa taagaggaat ggaaattgtc atccaaagat
     5341 tagtaaaaaa tggatggtca gacaagagaa tatccaaaga attaggcatg gacattgaag
     5401 aaatttttcg ctttaagcaa gtgtctggtg gaatggcaac agtttttttg acaaatttta
     5461 taaggtgcag aacttctttc cgtatgctat tccgattgtc cttgacaatg agcctcctcg
     5521 gatgtgacga tcttcggcag gagctaacag ttaaagttag actgcctcgc tagcgttagc
     5581 acatccgagc tcattatcaa ggattcgctg cgccaatctc tggttacggt aaccaaccgg
     5641 tgtctcgtag ccaagtgtac cgtgcaaccg aaggtggttc caccaattta catagtcaaa
     5701 taactccaaa tccaattgtt gtaaggtttc aaatgtgtat tgatagacaa attctacttt
     5761 caacgactta taagttgatt cagctacggc attatcaaaa ggacagcctt tatgactcaa
     5821 tgatcgattg atgtcaaaag ttgttaataa ttcatcaata gcttggttat caaactcttt
     5881 tccacgatca gtatgaaaaa tctcaacctc tgtcagaggt tgtttgatac ggctaaatgc
     5941 ttttttacta gaacggcatc tttatgttct ccacaagaat agccgagaat ttctcgattg
     6001 aacagatcca aaatgaaaca gacataattc cattttttcc cgactcgtac ataagtcaag
     6061 tctgttacga tcgcttctaa tgggttgtct cttaagaatt tacgattcaa tacgtttgtc
     6121 gttttggctt cattgcaagt agaatgatgt actttaaaat aagcaacagt atagctcgat
     6181 tttaatcctc tatttttcat gattctacta atttttcgtc ggctgatctg aatgcctcgt
     6241 tttgataagg ctttttttat ttttcttgag ccgtaggcct ttcggctgcg gataaattct
     6301 tcagcgacta cttcttcaag ttctgattcg tctttctttg gttttgattg ataataatag
     6361 gactgacgtg atagacctaa tattctgcac atcgctgata tagggtaaag atgcttattc
     6421 gcatcgatta cttgtctctt cgtccgaata tcagcgctgc ttgctttaaa atatcatttt
     6481 ccatttctaa ttgctggttt cttttacgta gttctaacaa ttctttttgt tcaggcgtaa
     6541 gattatcttt ttctttgaat gaaccactcg ttttagattg ctttac
//
LOCUS       DAFEML010000101         6466 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFEML010000101
VERSION     DAFEML010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.104"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(109..564)
                     /locus_tag="LP468_002532"
     CDS             complement(109..564)
                     /locus_tag="LP468_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082006.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="LP468_002533"
     CDS             complement(718..1926)
                     /locus_tag="LP468_002533"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL2082007.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="LP468_002534"
     CDS             complement(2038..2370)
                     /locus_tag="LP468_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2082008.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="LP468_002535"
     CDS             2518..3393
                     /locus_tag="LP468_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2082009.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="LP468_002536"
     CDS             complement(3475..4056)
                     /locus_tag="LP468_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL2082010.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="LP468_002537"
     CDS             complement(4062..5321)
                     /locus_tag="LP468_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2082011.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="LP468_002538"
     CDS             complement(5323..6369)
                     /locus_tag="LP468_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082012.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1803 a         1336 c         1102 g         2225 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcaatt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatctct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aataaa
//
LOCUS       DAFEML010000102         6452 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFEML010000102
VERSION     DAFEML010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.105"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(503..1312)
                     /locus_tag="LP468_002539"
     CDS             complement(503..1312)
                     /locus_tag="LP468_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2082013.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1312..2058)
                     /locus_tag="LP468_002540"
     CDS             complement(1312..2058)
                     /locus_tag="LP468_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2082014.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2076..2543)
                     /locus_tag="LP468_002541"
     CDS             complement(2076..2543)
                     /locus_tag="LP468_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2082015.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2543..2953)
                     /locus_tag="LP468_002542"
     CDS             complement(2543..2953)
                     /locus_tag="LP468_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2082016.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2964..3977)
                     /locus_tag="LP468_002543"
     CDS             complement(2964..3977)
                     /locus_tag="LP468_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2082017.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4194..4928
                     /locus_tag="LP468_002544"
     CDS             4194..4928
                     /locus_tag="LP468_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2082018.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVRNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4912..5610
                     /locus_tag="LP468_002545"
     CDS             4912..5610
                     /locus_tag="LP468_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2082019.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSHS"
     gene            6300..>6452
                     /locus_tag="LP468_002546"
     CDS             6300..>6452
                     /locus_tag="LP468_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2082020.1"
                     /translation="MSHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT         2053 a         1339 c         1117 g         1943 t
ORIGIN      
        1 caaaacatca gcttaaagcg acaaaaacca cgagcaggtc cattcatcct caaacctcgg
       61 tgatcttcgc ggtttaacac catcagaaga aatgcacaaa aataataagg agagtctgag
      121 acataaataa attcccagac ttttagtgag tctaaatccg aataaacggt gggtcgaaag
      181 caactctagc tgcgcgtcga tcgcagcaat ctctaggtgc tatgttcgga taaatggtgg
      241 tcaaaagtca gattttcggc catttcgtaa cagccaacca gacaaaaagc gtctgttttg
      301 tcttctactc caattgctca aatcttagcg acttttggct tggtcttact ctaaacagtt
      361 tgtaagccta aactttattt gctgtttgtt tctaagatca aagcaaaact actttttagt
      421 tggttacttt tacaagttct ttttactgtt gaataaatgt aaatcttaag aacaaatatt
      481 tacttctata attccaagtt tcttaaaaaa ttccgccaag tgtacctaaa aagcataaaa
      541 caaaaattcc tagaataatt gtgatcgttt tatgcccttt ggagtaaagc cagacgcata
      601 aaaaggtaat tcctaatggc agcaagcccg gaaaaatttg atcaaaaata ctttgtaatg
      661 aagtttcagc tccaccaacc gtgaatttta gtgacgtatt taaagtaacc atcgtgccta
      721 tcatcgcgcc aattaccgtt aaacctaaaa tcgaagcacc atgagataat ttgtcaatca
      781 tatggttgtc ttctgtatca tcaataaatt tagttcctaa aacatagcca tattttgtcg
      841 ccaaccattt aaaaataaaa tgaatggcag tatacaaagt aaaataaagg atcatgccta
      901 aaatattccc ttgttgagca aaagaaatac ctatgccagc cgcaataacc cgaaaagttc
      961 cccagaaaaa tgaatcgcca atacctgata aaggtcccat taatcctgtt ttgattttat
     1021 taattgcgtc tgtatcaaat tcaggatttt tagcattttc ttcttccatg gtgacggaca
     1081 agctcataac aaaaggcgca atatgcggtg taatgttaaa tgtttccgta tggcgctgca
     1141 acgctgtata ataatcatca tcgttcggat atattttacg taaggaacgt tcaataccat
     1201 tcatttgtcc atatgccatc attttatcga aggaccaaga ggattgcata aaaaaggagc
     1261 gccaaaatat acttcttaat tcttttttcc caataacact ttcttttacc attataaatc
     1321 ttcctcctct tcaaaagtta gcttttgaac agccagtaac gctaagcaaa gtccgacgac
     1381 agccacaccg acaacatcca ttttcagata cattacgccg acaaatccta agaaaagata
     1441 aggcatcatc gctttattcg ccatcatttt aattaataac gctagcccaa cacaagaaag
     1501 cacaccggcc gcaacatcaa agctgtccaa tacaacctga ggaatcaact tgatcatcgc
     1561 attgattgta gacacaccaa aataagtagc tacaaaaact aaaatggccg atggaacccc
     1621 aacgattaaa ggttgagcca cataatgata tttttgtgct tttttgaaat catgattgac
     1681 taatgcctca tccattttgt tgttaaaata cgtaattggc attgcatagg cgaagttacg
     1741 ccacatctga agaaagatgg acaaaggtaa agtcaacgca acggcagttc ctactccttg
     1801 acccgattga atcgcaattg ctgtacctaa aacactggaa gcataaactt cagggggcgt
     1861 cgcactccct accataattg agcccatgaa catggattcc aaggtggcac caataataat
     1921 tcctgactct aaatctccca aaatcaaacc gacaaaaggc gctgtaaata gcggtctacc
     1981 catcatcgat gcaccaaatg tgtattcatc aatagacgcc aaaaaagcta ccagtgcgat
     2041 taatattgct tgtatcatat tcttcccctc ctcttttagt catgcaaagg attgattttt
     2101 ttgtccgttg gtacagcctg acattgaact gttatcccgt tttcagtcat ttttttcacc
     2161 aagtccagtt cttgttcatt caagtaaacg gaactagtaa tcattttccg attctcgttt
     2221 ttctttaaat ttcctaaatt cacttcttta atctcaggta cgtgctgagt aatttcgtag
     2281 gcatcctcca ccgtcccgac aattaaaaat acttggtatt tcttgatttt ttctccattt
     2341 aaaacagaga tggcctctgt catatccttc accacaaatt ttgtccctgt aggaacagcc
     2401 atttttagtg tttttttgcg cagattattg gtagcgattt cattacttgc aacgaaaata
     2461 caatttgcac ctaagttatt tgtccaggca aaagcaactt gcccatgaac aaaacgttca
     2521 tctactcgta ataatttaat cattaaaaat catcctcttc tgttttctct agcaactcgt
     2581 tcaccaaaac tatcccttca ttcccgctat tcatagcttt ttggattagt tttttcgtgt
     2641 cctgttcacc tgataagcaa agctctaaaa gcagcggcag atttacaccg ctgattaaat
     2701 aaaaattgtc tttaccgatt tgttcggaga aagcgttaga cacgcttcct cccagtaaat
     2761 ctaccgtcac aattaattcg tcatcaggcg ctaagtcgga aaatagctgc tctatttcct
     2821 ggttaatgga gtagtcacta tctatatacg cagttattgc taaaagtgat ttttgaggac
     2881 caataataaa ttctaaagta tcctttaagc ctttagccat catggaatgc gtcgcaatta
     2941 caattttcct catagctctt accttaatat tccacagtcc gataataacg acgaatatct
     3001 agtgaatgat cccgcacctt ttcaaaatga gcactcactc gttctaaggc cgttgccata
     3061 accattggcg ctacatactg acgcatagcg cttggtacac ctgctaattc gaaatccgca
     3121 gtgtcaaaaa ccgtcacaac atcgctatat ttatttacaa aacgctctac gcgatcgact
     3181 agcggacgcg tttgatcttc accttttaat aacacaaaac tcatagattt atcagtcatt
     3241 tcaatagtcc catggaaaaa ttcggctgca tggatcgact tggtggcaat ccattgcatt
     3301 tcttccagta cgcacatagc atattcatag gcagccccat aagtattccc ggctccaaca
     3361 aacatatgaa attccgtatt tttatgtttt tctgcaaatt caagtgcttt ctgatcattt
     3421 tgttgccgaa cacttagtaa tacttccggc attttttgta atgtttgaat aaattcatca
     3481 tattcaggaa actcaccgtt atttttcatc aggcgtgcac ccaaagcaaa aaactgtaac
     3541 tgaagttctt ctactaatgt atcgttgtca gcatcatttt caatcgcata atccacgatt
     3601 tccccgagtg gtgtagcagc atttcctaca aacgcaatcg tcgttgcacc ttgactattg
     3661 gcatacttaa caacatcaac ggtttcttga gtcgtaccgg ttaatgaaga tgtgattaac
     3721 actgtatctt tattaatctt tttcggctgt gaacaaacca cctctgcggc tatttcatga
     3781 taataatcaa gctctgaatg agtgcttaac agataagcta gcgggctgat tgtggcatat
     3841 gttccaccag agcctaccaa ataaagattt ttaaatccct tctcactgat tgcatctgcc
     3901 acctgattga ttgtctcgat attttttact gcaccattta atactgatag aaaacgttct
     3961 tcgctaaaac ctaacatagt taaaaacctc caagtcaata atttgaaaaa tatatttgca
     4021 aatgccggca cattaacaaa ccacttaatc ttttttatat accacctgtt aacgttttta
     4081 atgtaccact tatagaaaac gctgtcaata gtttttaacc acttttattt ttatttgtac
     4141 caaaatcctt ttttcatgta taataaacaa aaatagactc tggagtgtaa cgtatgaata
     4201 ctgaagaact aacgaacaaa ttaatacaag acattgaaca agaaaaatat aaatacgcgc
     4261 aagctattcc ttcagaacgt gattttgttc aaatttatga aatgaatcgt tcagccgtaa
     4321 aaaaagccat tcaacaatta gtaaataaag agtacctact aaaaatacat ggcaaaggaa
     4381 cttttgttaa aaaaaatatc catgaacatt tgcaaatcaa atttcatggt ttgtctgaat
     4441 tgttggaacg ggaagggatt cagcctagca gcttaatttt agcttcagaa ataaaaccgg
     4501 ctggacacat tgtcgggaaa gctttacagc tggaaccaac tgaagaagta tttcatttgg
     4561 ttcgtttaag aagcggcgac ggtgagccaa tttctattga agacacttat attccattaa
     4621 atctcatacc tgatcttcaa gcttttgatt tccaaatttt ttcattttat tccacattgg
     4681 ctgcttatca ttatcaaatt gaaaatatct atcagacaat ttccagctca aaagtgcgca
     4741 ataaagaagc ccgtttgtta aaaaccagct taaatcgtcc ggtaatcagt cttgctatca
     4801 ctgcggttac gacaaatgaa caagcggttg aatacactga agtagtggtt ttgcctgaat
     4861 tcgccgccat ctatactaaa aatgttcatc aaggaaagga gatgaaaatc tatgcccaaa
     4921 ttgattaatc tgttggctta tgacctgatt gacaaaatta ttgcttatat tcatgaacat
     4981 catttaaccc ccggaacaaa actgccttcg gaacgggacc tatcagaaat gtttaatgtt
     5041 aatcgaacta ccttaagagg cgcgttacaa aaactggtgg acaacggcac cttacgggcg
     5101 caaaccaata gcggctatta tttaactgcg ccaaaattcg aaaaaaatgc ccatcatttc
     5161 tttacaccga tagaagattc tctgcttagt aagcagcggc tacagctaaa ggcaacggct
     5221 ctttcaccga aaaaagcagc agctctttgt ccggaactga atgatttcaa acagcagcaa
     5281 ccacaagctt atttagaata tattgatgca gaagcaatta gcttgatgtt attaatccct
     5341 atggaaacat taaagaaaag taatttctcg gacaatcctt tccaagattt taaaagtttg
     5401 gcatatacgc gttctcaaga aatttcttta ataactgaca atgacgttgc ggcggacttg
     5461 ctgggagttg acaaagaaga ggttctgtta tttgtacgag aggaaataag agccggtaag
     5521 gagttggcgg cgattgcttt aggttatact attagtcgcc gctgcaacat acaggttaat
     5581 gttgctacga ccttgcaatc ccatagttag gaaaaactat tcgctgtaag ttcaaccgtt
     5641 tcaatgcaag cgaatcacaa atcaaaaagt atttaactcg tgtttattag aaatagtcat
     5701 gaacttttag tctccaagat caaaccgaca gcgttcaact ctgagaagca aaagtaaatg
     5761 tacgatcaag tatgaggctg ggacagaagc gctaagctcc gagaaccaag agaaggtacg
     5821 ttcattatcg aatcactgca ttcttcgtgt ttatcagcaa tttcggctta tttccgcagg
     5881 ccttcaagaa ggttgaagca aaagtcgttc agatttgagc aattggagga aaaggcgctc
     5941 cagacgttcc ttgtctggag cggctgttat gaaatggccg aagatctgac ttttgaccac
     6001 cgtttaatca aggttgagcc aaaagtcgtt caggtttgag caattggagt agaagacaaa
     6061 acagatgttt tttgtctggt tggctgttac gaaattgccg aagaggctga tttttaacca
     6121 ccgtttatct agtcatagca cttagagatt gatgcgatcg acgcgtagct agagtggctg
     6181 ccgctgcaat gacccgtggc aaaatatact gctttttcat ttttcggttc tgttgcaaag
     6241 ttttaaatct actatcagat aaggtagaat aatagaaaaa gatagcagga ggaatgacga
     6301 tgagtcattt taaaggaaag caatttcagc aggatgtgat tattgtagcc gtgggctact
     6361 atcttcgtta taaccttagc tatcgtgaag ttcgagaaat cttatatgat cgtggcatta
     6421 acgtttctca tacgacgatt tatcgttggg tg
//
LOCUS       DAFEML010000103         6287 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFEML010000103
VERSION     DAFEML010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.106"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..177
                     /locus_tag="LP468_002547"
     CDS             <1..177
                     /locus_tag="LP468_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082021.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="LP468_002548"
     CDS             190..690
                     /locus_tag="LP468_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL2082022.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="LP468_002549"
     CDS             787..2634
                     /locus_tag="LP468_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBL2082023.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="LP468_002550"
     CDS             2637..3533
                     /locus_tag="LP468_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2082024.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="LP468_002551"
     CDS             3583..3972
                     /locus_tag="LP468_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2082025.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6287
                     /locus_tag="LP468_002552"
     CDS             3959..>6287
                     /locus_tag="LP468_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2082026.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1348 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacg
//
LOCUS       DAFEML010000104         6173 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFEML010000104
VERSION     DAFEML010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.107"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            725..811
                     /locus_tag="LP468_002553"
     CDS             725..811
                     /locus_tag="LP468_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2082027.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="LP468_002554"
     CDS             complement(932..1621)
                     /locus_tag="LP468_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082028.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="LP468_002555"
     CDS             complement(1628..1906)
                     /locus_tag="LP468_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082029.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="LP468_002556"
     CDS             complement(1866..2780)
                     /locus_tag="LP468_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2082030.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="LP468_002557"
     CDS             complement(2762..3142)
                     /locus_tag="LP468_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL2082031.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="LP468_002558"
     CDS             complement(3592..3879)
                     /locus_tag="LP468_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2082032.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="LP468_002559"
     CDS             complement(3899..4123)
                     /locus_tag="LP468_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBL2082033.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="LP468_002560"
     CDS             complement(4578..4748)
                     /locus_tag="LP468_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082034.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="LP468_002561"
     CDS             complement(4763..5296)
                     /locus_tag="LP468_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2082035.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="LP468_002562"
     CDS             complement(5317..6159)
                     /locus_tag="LP468_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2082036.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1634 a         1153 c         1041 g         2345 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaacaaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtacatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFEML010000105         5877 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFEML010000105
VERSION     DAFEML010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.108"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            641..1375
                     /locus_tag="LP468_002563"
     CDS             641..1375
                     /locus_tag="LP468_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2082037.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="LP468_002564"
     CDS             1391..2560
                     /locus_tag="LP468_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2082038.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="LP468_002565"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="LP468_002565"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2082039.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYAEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="LP468_002566"
     CDS             3650..4576
                     /locus_tag="LP468_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBL2082040.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="LP468_002567"
     CDS             4595..5845
                     /locus_tag="LP468_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2082041.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          956 c         1203 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgcagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DAFEML010000106         5468 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFEML010000106
VERSION     DAFEML010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.109"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            63..641
                     /locus_tag="LP468_002568"
     CDS             63..641
                     /locus_tag="LP468_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL2082042.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            645..1166
                     /locus_tag="LP468_002569"
     CDS             645..1166
                     /locus_tag="LP468_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2082043.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(1245..1799)
                     /locus_tag="LP468_002570"
     CDS             complement(1245..1799)
                     /locus_tag="LP468_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2082044.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            2052..2327
                     /gene="rpsP"
                     /locus_tag="LP468_002571"
     CDS             2052..2327
                     /gene="rpsP"
                     /locus_tag="LP468_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL2082045.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            2339..2590
                     /locus_tag="LP468_002572"
     CDS             2339..2590
                     /locus_tag="LP468_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL2082046.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            2715..3506
                     /locus_tag="LP468_002573"
     CDS             2715..3506
                     /locus_tag="LP468_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082047.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            3676..4197
                     /gene="rimM"
                     /locus_tag="LP468_002574"
     CDS             3676..4197
                     /gene="rimM"
                     /locus_tag="LP468_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL2082048.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            4187..4948
                     /gene="trmD"
                     /locus_tag="LP468_002575"
     CDS             4187..4948
                     /gene="trmD"
                     /locus_tag="LP468_002575"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL2082049.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            5084..5431
                     /gene="rplS"
                     /locus_tag="LP468_002576"
     CDS             5084..5431
                     /gene="rplS"
                     /locus_tag="LP468_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL2082050.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
BASE COUNT         1896 a          985 c         1095 g         1492 t
ORIGIN      
        1 ttttctatca gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac
       61 agatgagatg tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct
      121 ggggtgttcc tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc
      181 aagccggatt gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg
      241 atcgattcga tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg
      301 aaaacaaagg aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag
      361 cagtcttgaa aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta
      421 atggaaaaat cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc
      481 tttcagatga attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa
      541 caatctatgc ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc
      601 gcaaagaaga ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat
      661 tttatggtgc tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc
      721 tttttgacac tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata
      781 cgaccatcat gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa
      841 tttatccaga gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg
      901 ctgaggtcgt aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa
      961 aagatatctg ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga
     1021 ttgatgaatg gtatatccag attacccctg tattattagg ggacgggatt cctttattcc
     1081 aaaaaggaac atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta
     1141 tcgaattgca ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag
     1201 aaatgtcctg tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg
     1261 ttagaaaaat ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg
     1321 atattaccat tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc
     1381 aaggttggca cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg
     1441 ccgatcccac ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt
     1501 ccataaggtc ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg
     1561 tattcaggag taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc
     1621 cattcagcag gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg
     1681 atttttacaa atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact
     1741 tttttgttgt aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata
     1801 cgatttttcc tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa
     1861 ataaaaacac ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa
     1921 gaagtctaaa atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa
     1981 aagctttaca gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt
     2041 ggaaataaat aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt
     2101 tttaccgtat cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg
     2161 taggtactta caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc
     2221 ttgactggtt atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag
     2281 aaggcgttat gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat
     2341 gaaagattta agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca
     2401 agtcaagtta gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc
     2461 tgaagatatt ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat
     2521 cgtttacggt gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa
     2581 ggaaaagtaa ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta
     2641 ttaattgaag aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag
     2701 ggagtgaaca gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg
     2761 cttgtagttc ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa
     2821 ctgttaccag tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg
     2881 ctacctcaaa taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg
     2941 ttcccatgcc tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata
     3001 caaagcaagg ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg
     3061 acgaattgaa tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta
     3121 gtcaagaaac aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtag
     3181 acttaggttc tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat
     3241 ggcaagaagg aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct
     3301 tactattagc taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac
     3361 aatttggtaa aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct
     3421 ggcaagaacc gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga
     3481 tggcagtttc tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact
     3541 ccaagtcaca ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat
     3601 accttaaaag aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag
     3661 aaatggggat ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt
     3721 atcaaaggcg aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa
     3781 ggaacggtgc taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt
     3841 catcgcaaac ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat
     3901 gtggaaaaat atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct
     3961 gaaaatgaat tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag
     4021 ttaggtaaag taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt
     4081 ccgaaaaaag ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta
     4141 gaagctggag tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt
     4201 attgacttta tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc
     4261 tgtagataaa ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa
     4321 acatcagaca gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca
     4381 gcccatctat gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt
     4441 aattcttctt gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca
     4501 agaagaacac ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac
     4561 attagtgaca gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc
     4621 gatggtcatg atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc
     4681 agctcaaacg gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc
     4741 agaatataaa gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga
     4801 agaatggcaa ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga
     4861 aacacttgaa tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca
     4921 agaaaaaaca gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga
     4981 taatatgtta gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt
     5041 gagaaaagct cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga
     5101 agaattaaca aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt
     5161 gcgtgttcac gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt
     5221 tgttatcaaa cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa
     5281 cggagtgggc gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt
     5341 agttcgctac ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa
     5401 agctgctcgt atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa
     5461 tttgtgaa
//
LOCUS       DAFEML010000107         5374 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFEML010000107
VERSION     DAFEML010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.110"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..371)
                     /locus_tag="LP468_002577"
     CDS             complement(<1..371)
                     /locus_tag="LP468_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082051.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLL"
     gene            complement(504..908)
                     /locus_tag="LP468_002578"
     CDS             complement(504..908)
                     /locus_tag="LP468_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2082052.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(1141..1776)
                     /locus_tag="LP468_002579"
     CDS             complement(1141..1776)
                     /locus_tag="LP468_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2082053.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2042..3094)
                     /locus_tag="LP468_002580"
     CDS             complement(2042..3094)
                     /locus_tag="LP468_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2082054.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3107..4045)
                     /locus_tag="LP468_002581"
     CDS             complement(3107..4045)
                     /locus_tag="LP468_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2082055.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4496..5146)
                     /locus_tag="LP468_002582"
     CDS             complement(4496..5146)
                     /locus_tag="LP468_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082056.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5246..>5374)
                     /locus_tag="LP468_002583"
     CDS             complement(5246..>5374)
                     /locus_tag="LP468_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL2082057.1"
                     /translation="YPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKGLGIYNRRKV"
BASE COUNT         1722 a         1146 c          790 g         1716 t
ORIGIN      
        1 agcagtttga tcggctgtcc tgtttctcta tccagtacat gaataataga atgatgctga
       61 tggtcatagc agtaggcaga aataaacaca aaatcttgag aaaaagccaa cccttgcggc
      121 gtcatccatt gacaaacctc attttcgccg gtttccggca ccaccattct tgtttctgtt
      181 aatccaggaa tgttatattg ttttgcttca gccttttccc aagctgcttg aacaatagga
      241 taccgtttta actttttttc aatatcctga tgtatccgtt gctgcttcca atgcttaaac
      301 tttaggacat agtaaacaag aaggccaatg accagcaaca ctaaaatcat tattgctacc
      361 cgctgtgtca tttttttgcc tccttgttct attcgatcaa tcgtccatat accgctatta
      421 attaccgtaa ctacatgttt cttttactag cgtttcttta taggatcttt cataatctca
      481 tttatagtaa cattaagaat cccttattct actatagtca cttccacatc aatattgcct
      541 cttgttgctt tagagtatgg gcaaaatgcg tgggcttctt ctgcgatttt ctctgcttgg
      601 tccttctcaa gtcctggcaa agaaacttct aaaacgaccc cgatttggta gcccccatct
      661 tctaattgaa ataaagatac ccgtgctttg acttcagaat cagactcaag attattttct
      721 tccagcatgt gttgaaccgc gccgttgaag caagatgcgt atccagccgc aaaaagttgt
      781 tccggatttg tcccttcact atggattcct gggcggtcga tcttcatgtg catacttccg
      841 tttggtgcct caacttcgcc atcacggcct ccacgattga tcattgctgt ttcgtacatt
      901 tttttcattg agatcatcct ttctttcgtc gttctatatt aagtgtaacg agtatttttt
      961 aatctgacaa aggtaatgct tgcattcggc gacatcagtt agacaacatc gatgatcagt
     1021 gatagaagca gtttatctat acaaaaaaag aagggttcta tgatatttgg tgtccttact
     1081 cgccttgagt aacaacacca aatatcatag aaccacttaa tcagcttcac actgcttttt
     1141 ctactttcgt agttgaaaaa aacttaaaca aatcatcggc aaatagttaa agaaaaaact
     1201 taatcgttga aagaagccca attgcttaaa gaaggcaaac tgactaatcg acggaatccg
     1261 tgctaatccg taaagacctg caattagtaa actaataact gttaaaacaa gataaaaatg
     1321 gctaagcgta ccttgaccac tttgacgata aagcagaaca agtaacaatg ggaaaagtag
     1381 aaagcctgca tagcctagcc cagaacctat attatggatc caagtcgata gattacaaga
     1441 gctttcattc gtattgatac tgaataagcc agtaaaaata caatcaccta tcccatataa
     1501 accaactgtt gcaacaacaa gtattgcaag tgtttttgat gttccaacaa ataggtgata
     1561 caacgcaggc aacgaaagaa caaaaaaaag tccagataca actgaccaga ccaagaaagc
     1621 acgtctgact ggactatcta cgtcaccaaa cacactaatt acggtagtca tttgattcag
     1681 tttgggataa aaaaggccaa ggatatacgg tgtcgataaa tcactcatca cacctaataa
     1741 taaaaaataa aaaccatatt tttgcaaaaa aatcattttc ttcccctact ttttagtgat
     1801 tattcgatac atccaacaat caaatttttt ctcattttaa cacatatttt tattctagtt
     1861 gtcttttgaa caatcaataa cataaaggtg agtttcttct acattttaaa aaatcgaatg
     1921 gcactgaaga gttcagttgt cagcatcaat ctcctactca aaaaggcaaa aaaacgtaag
     1981 tcagatgttg ttgacatctc acttacgcat ccattgattg aaaatttctt agtaaaatct
     2041 actagcctaa aaatttgaag acttcttctc gatcatacag tttaaatact ttctcgcata
     2101 aaaattgagt aattagtgcc gcaaaaacag ggatgactaa ccaacaaaga acaacaagaa
     2161 agccatttag ccctgcatct aaagaagcca acggaccaac aagtccgacc acgccgaaac
     2221 cagcagaagc aggcgtacct gaaatagaaa atagagcgac aggaatagct gtaatcactg
     2281 cactaactaa acaaggaata agaatcacag gttttctaaa tagattaggc atcatcatct
     2341 tcatagcgcc taaagcaatc gcaattgtca cacctgactt attaaccttc caagagttca
     2401 ctactaaaac aaaagtggtt gcagctacgc ccatcgcagc cgcaccagca gaaacaccat
     2461 ctagttggat tgccattccg attgctactg ttgaaatagg agagataatc aaaaaggcaa
     2521 aggaacaacc aatcaagata gacattaaca gcggttgtaa ggtagtgaag ttattaatca
     2581 atgatccaat tgcagaagta attgctgtta caaaagggaa taaataaaaa ccaagtaaac
     2641 ctgcacctac acctacaaca atcggtgtta acacaatcga cactgaccca aaactatttc
     2701 caatcagtaa aatcagcccg acagcaatcg atgctgtcag catcgtatta ataatatcgc
     2761 ctgtaccagc accaacgtaa acacccgttt cacccaaatc aggtgtgaat ttgactacac
     2821 cagaaccaac aaaagaagct ccggctacaa ccatcattct catcggatca aatccaaatt
     2881 gtaaggcaat caaaccacca atgatcaaag gtgttgctag ttgaaaaata actgctaact
     2941 gtgcgatcgt taccgcaaag ggatacgcac taaaatattt taaaatggca cctaatactg
     3001 cattaggaat caatccaata atgattcctg ttgctgtacc agcgaggact ttattcagaa
     3061 aaattttcgg tgatattttt tgtgaagttt ccattcaatc tctcctttat tttacgttca
     3121 aactatcttc ttttgcatgg acaagctcag tcaagaaatc acaataaggc gtcgcaacac
     3181 catatttctt cccttttcta gaaattgcgc cattgatata atcgatttct gttaatcgat
     3241 ggttcttaat caagtcttga tacattgaag gataatgtaa cccaattgtt tccgggtcaa
     3301 aacaagattc acaatgtgca atgacttctg ggacatctag ttcaatcttc tctactgctg
     3361 ctactttggc aaactcattg acaatcgtcg ccaccatttt atgagcagtc gatgtttttc
     3421 ctagctcagc catattaacg tctaagattg tgcatagtcc gttcattgtt ccgttcacac
     3481 atgctttgcg ataaatagaa tagtgaatat tgtcagaaaa atgagcattt aatcctgatt
     3541 cagacaattt gtctgctaat ttttttgcag ctgcttcttt tccatcacct aaattttgta
     3601 attctactga accacttcca aataatttga cctgaccagg accttcaaga cctgccgtcc
     3661 acatggtatt tccaatatag atattttcca ttggtacaaa tttctcaata atatcttcat
     3721 gcccgatacc atttaataga cataagacct ctgtatcttt tttgattaat gattggatat
     3781 cctgcagcat tttttccagc tgcatcgctt tggtaaatag aataatcaga tcaacttgat
     3841 cttctttttc tacttcggat tgaagaacga ttggtagttt tgcttctacc tctttaccat
     3901 taaaatttgc ttgtaatcca tgttctttga tttgttggac atgttctgcc cagccatcga
     3961 ttaataatac ttcgttccca ctttggtgaa gcatcaaccc aaagcgactt cccattgcgc
     4021 cagcgcctgc aattgctatt ttcattgatt cttcctcctt tttctttcta ttatactcat
     4081 ttgagaatct tttcacaacc tcgttttgtt attcttctct tatttatcat gtttatatcc
     4141 accattcaag ttattttatc agcaaatcaa taaaaactgg aatagaatcc caatttcatc
     4201 gtaagagaaa ctagactagc aataagaaaa tagaaacatt catagaaaaa atctcactcc
     4261 tctgattata aaagaggggg cattaacctc gtgtatacta aaaccttcca ttcattcgat
     4321 ggatgatttt ctttttgtga aaaaatattc attgtagtac gatgttgcgc aacacagacg
     4381 gatggtattg cttattattt attaaaatcg aacaatacac ttatttaaaa acttctttcc
     4441 cagattttct tccattttta cagttataac tagtattatc atgaaaaata gccttttatt
     4501 gtctatggga ataataattt aaaattggta cttttttatt aattagttca tcgcccaata
     4561 atctctccag tttcttagca tctcctgact caaccggaat tatccaagcc cagtctaaat
     4621 aattttttaa aatctcatca tattttgcaa atatttcatt gccatattcc gtccttaaaa
     4681 ttatattttc agtgccagac aagtgattta tattgagttg ataaaaaaga tctccatcta
     4741 aaaaaatatc attagaagaa gatttcccca cagtaatgac cattccatca gctctatgtg
     4801 ttacatacaa ataattgtat gacctcattt cacctaatga atcaattatt tcttgccctt
     4861 tagctctaat atattgatct ctattaccta tctcactctt atttaacaaa agttttttca
     4921 tgtcaaattt aatcggctgt tttatttttg taaattcgct tctactacta atccaatccg
     4981 agattaattt ttcaacatgt cccagagtaa actctgattt attcgctaaa tacttttttt
     5041 gttgtattaa agacatcttt ccccgaagct caaaattgag cctacatcga ttctctatct
     5101 cttcaaaaag catcttatct tcatcattct tatattcatc attcataaaa ccaatccagc
     5161 tcctcgatta agataatatt ttaatctcat acaaaaacta gctctcatca aaacaaccat
     5221 tgttttgatt tctcatgaaa tttctttata cttttctccg attataaatt cctaacccct
     5281 tgagaaaatt acgcatatat ttatctccgc aaggcttaaa atttcgttgg ccttcttttc
     5341 tcaaaaatgc cccgatttcg ccttttgatg gata
//
LOCUS       DAFEML010000108         5341 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFEML010000108
VERSION     DAFEML010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.111"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(62..280)
                     /locus_tag="LP468_002584"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="LP468_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="LP468_002585"
     CDS             complement(546..740)
                     /locus_tag="LP468_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082058.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="LP468_002586"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="LP468_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="LP468_002587"
     CDS             2092..3132
                     /locus_tag="LP468_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL2082059.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="LP468_002588"
     CDS             3956..4288
                     /locus_tag="LP468_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL2082060.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="LP468_002589"
     CDS             4907..5248
                     /locus_tag="LP468_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL2082061.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DAFEML010000109         5212 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFEML010000109
VERSION     DAFEML010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.112"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            604..954
                     /locus_tag="LP468_002590"
                     /pseudo
     CDS             604..954
                     /locus_tag="LP468_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
     gene            948..1370
                     /locus_tag="LP468_002591"
     CDS             948..1370
                     /locus_tag="LP468_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082062.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2540..3508
                     /locus_tag="LP468_002592"
     CDS             2540..3508
                     /locus_tag="LP468_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2082063.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3525..4049
                     /locus_tag="LP468_002593"
     CDS             3525..4049
                     /locus_tag="LP468_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2082064.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTETHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            4425..4706
                     /locus_tag="LP468_002594"
     CDS             4425..4706
                     /locus_tag="LP468_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082065.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4708..5124
                     /locus_tag="LP468_002595"
     CDS             4708..5124
                     /locus_tag="LP468_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082066.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1968 a          893 c          867 g         1484 t
ORIGIN      
        1 aaaaaaaaga aaaatccgct tatgcaactt cttctttttg tattttgggg cgctacccca
       61 atccccaagt atcggttatt taatagcgcg gaaatccaaa gaataggacg taccctgaaa
      121 caaaaaaaga ctgctctcac gagcagccca aaatgagatt atcctattca tcaacataaa
      181 aatattacaa agtgaagaac tagagaaaga caaaaaaagc atatcaaatc ctctcaaaaa
      241 taacaagtct taaaaaaatg acagataaaa atgcacaaag aattagatat agataaccgc
      301 gaaaaatcaa gctttagaaa gttgctttta gctagaccaa ttaaaaatca caaagtgagc
      361 gtctctatcc attggtagag gggctacttg gcatagtgta cattatgtta actagctcga
      421 taaataacga ttatgttccc aaaacaatat tttatgaact ataacaaaaa tttgttatcg
      481 catattgtat attttaatta tataattata ggtgtatacc acttaaattt aacacaaagg
      541 cgtggttatt ttgaaaccca aaaagaaaat ttatctaggt ctcctctttt ccttgatgat
      601 tggaatagtc aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat
      661 tactgtggtg tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca
      721 caactaagaa aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac
      781 agccgtcatg cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat
      841 gtgtggaatc cttggtataa ctacccaact gtaataagtg caaatgcagg accagttaca
      901 attcctgtac ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac
      961 ccattgcttt agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac
     1021 aagaaataca aaagactgat ctgattcctt ttctaggaac ttggcaaact aaagatcatt
     1081 cagaacgtct agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct
     1141 tagtaaaaga gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac
     1201 aagttttcat ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat
     1261 tagattacac ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg
     1321 atgggacaga agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg
     1381 tttgatatta caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt
     1441 ggctagcatt tgctagcctt ttttgtattg tggagcgtgg tttttgaggg ggattcaagg
     1501 gggagcttgc gcccctttga caagcggtta tttgcaccaa atacgtaggt atttggctag
     1561 caaatataga gcttgccaaa cactttagtg agttttgtag aaagtacctt taaaggtact
     1621 ttcacattac gaacgatacg tccgtaggac gtactgaaag ggtgggattt atgagcgaac
     1681 taatgcaaaa tttggctagc aaaaaaagtt aaaaaatata tgctaataat cgagcgaaat
     1741 gaacactttt tcaagtgagc gaatccgcca tgacaaagct gaagcagttt atttcagctt
     1801 tgtcatggcg tgtgcctaga cttttaaaaa agtcggcaca cgagcaaata tctttatcaa
     1861 gctctaattt gcgttttaag acgtttgaaa cgtctaagta tataaatata taagagtagg
     1921 tttaagagtg cttaaatcga attttagagg gcattcagac aactttaggg ttgttagggc
     1981 ttgccctgac cgcctgtaag gcgctttaag aacaagataa gggatttata ctaagactgt
     2041 cttaaaacgt ctcaaacgaa ggctcatagc ttctcaaaga gttccttatg aacattttta
     2101 gcaaaggagc cggaagcgac tgcgcagtat aatgtgagag cagagcgatc acaccttttt
     2161 aagcgactgt agggagtaag attcccagtt gagaaaaatg cgcgaatctg tttggagaaa
     2221 aaagaagtgg ttttttaggc gggaaatttt gtccccctct tttataatct ctttttaaac
     2281 ctctttttaa acctctttac cgtcggctat atccttactc tcccaaggga atgacgcttt
     2341 tatctacatc gttttgtctg tttatctaca tcgttttgtc tgtttatcta catcgttttg
     2401 tctgtttatc tacatcgttt tgtctgtttg tacattgaat tagtacatcg acgatgttaa
     2461 tataagatgt agataaacag gcattttgta tttcataacg tgtatctctt gtgcgagtaa
     2521 gaaaggagct attttaaata tgtctaatga aatcgtaaag tatcatcatg aattaaatac
     2581 aattccgttg cgaaaattta caccagtcga aatgaatttg ttcttttcta tcgtatcaag
     2641 aatgcgtgat gtaggtgata aaaaagtaca atttacattc gagcaattaa aagatttaag
     2701 caattataaa gcaactgcaa atgttcgatt catagatgat ttagaaacaa cgtatgacaa
     2761 attaatggat ttacgttttg gtagaagaag tgctgacggt ttgcaacgtg aacgttttgt
     2821 tttatttaat caatttaaaa tcgacggaaa atctgatatt ccttttgctg aaatacaagt
     2881 tcatgaaaaa gccttaccct tacttaataa tcttgaagaa tgggtgcgct attctctcca
     2941 acaattcaat gaattagaaa gcagttattc aaaaacaatg tttcgattac taaaacaata
     3001 cagaaccaaa ggtttcgctt atttttcaaa agaagacttt catgaattac ttgatattcc
     3061 taaaagttac aaccaaggta cgattgatca acgtgtgttc aatccaatac gacaagaact
     3121 aaccgcaatc tttaaaggtt taacaatcaa aaagaaatac ggaaaaggac ggggaaagcc
     3181 tgtcattggc tatcaattta catttaaacc tgagataaaa aaatcagacg actttaacaa
     3241 acatgcccca acaaaagaag aacaaaacaa agcattagaa ctagctaacc aacaagttca
     3301 atctgaaaaa gcacctactt cattacaaga aaaaatcaaa gaacaaaagc gaaaattgga
     3361 acttttacaa cagttagaaa agttagaaag agaacaaaat acccaaaata aagaaaataa
     3421 tgcacaaaaa tcagagataa attccgatat tccttcagaa ctaaaaaaag acttattaga
     3481 caatcttcaa aacttattca aagattgagg ggtttttaga ttttatgaca gaaaaaacaa
     3541 tcaaagaact tgctgaagaa ttaggagtta gtaaaacagc aattaacaaa aaagtttctg
     3601 acgaaaatcg aaaactttgg ttttcgaaaa tcggaaacaa gtttgtgatt aatgaaaccg
     3661 gacaaaaggc tataaaatca atgtttttta acgaaaacga aaactcaaat caacaactag
     3721 ttggcgaaaa aacgaaaacc gaaacccaca aaaacgccaa ccaagttccc gaattagaag
     3781 tcctttctct cctagaacaa cagttaaatc aaaaagatat gcaactacaa gaaaaagacg
     3841 agcaaataaa acaaatgcaa aaattactcg accaccaaca acaactcacc ctgcaagcca
     3901 accaacaaat cgagaaactg caggaacaac tacagttgac ttatacggaa gaatcttcgg
     3961 aaaataaatc aacgactctt tctgaagaaa cagaatcgat agaaaaacaa tcaaagacgg
     4021 agaaaaaatg gtggcaattc tggcaataaa accagcaatt taaattaata aaaattgctg
     4081 gttttattct tctttttgct tttgcgagca gagcaacatg gacccatgtt gcgatatttt
     4141 ggtggcgccc caatccccgt tttttcgttg aatcttactc ggactgcact cgttttacag
     4201 ctgatttttc tgaattttga aagagcataa ggaaacgtgg tatcactttc ttacgaaagg
     4261 tgctagatag gctgtgccta tcacgtttct cagaaaaaaa tttgctatca cttttttgcc
     4321 attgtggcta ggctatgtat agtgttttgg cgaaaaatag ctatacaaat actatatttg
     4381 tatgatatac ataaattata cgctgatacg aaaggaaaat ttccatggac attttagttc
     4441 gaaatatcaa tcccaaaatt attgcaagaa tagataaacg ttgtcaggaa ctcacaacca
     4501 aaacgggcaa aaaatggagt cgaaataaat atctaaaagt tctaatcgaa agtgattttg
     4561 accgtcaact tatgaattac aaaaaagatc aattcgattt attactcgaa aaatttattg
     4621 ccattcaaac agaaaatacg aacatactga atgactatgt tcacacaaac aaccaactca
     4681 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgtaacc
     4741 ctttatccca gtcacgttga cgttttagat tccatcatcg aaaaaaatcc agacgtcaac
     4801 aattattcag aagccattcg ttttttatgt atgagttatg aacctgatac caatacaacc
     4861 acaaccagta accaagcaaa actcaatgcc atgggaaaag aaatttctat catgacagaa
     4921 atcatggcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4981 tctaaagtgt atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ttcccgacga
     5041 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacct ttacttctgg aaattttgac
     5101 ccaacaaact ttctaaaaag ataaaaaaag aaaccgatcc ctaaaaaaat tcctcgattt
     5161 ctttttaggg atcagtcttc cagcaagatt tgcaagttgg taccaacttg cg
//
LOCUS       DAFEML010000110         5021 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFEML010000110
VERSION     DAFEML010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.113"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(207..1169)
                     /locus_tag="LP468_002596"
     CDS             complement(207..1169)
                     /locus_tag="LP468_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2082067.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LP468_002597"
     CDS             complement(1171..2610)
                     /locus_tag="LP468_002597"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL2082068.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LP468_002598"
     CDS             2795..4741
                     /locus_tag="LP468_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL2082069.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1629 a          837 c          814 g         1741 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa t
//
LOCUS       DAFEML010000111         4951 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFEML010000111
VERSION     DAFEML010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.114"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(334..696)
                     /locus_tag="LP468_002599"
     CDS             complement(334..696)
                     /locus_tag="LP468_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082070.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="LP468_002600"
     CDS             complement(770..1150)
                     /locus_tag="LP468_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL2082071.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="LP468_002601"
     CDS             1214..2407
                     /locus_tag="LP468_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2082072.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="LP468_002602"
     CDS             complement(2484..3068)
                     /locus_tag="LP468_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2082073.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3269..4267
                     /locus_tag="LP468_002603"
     CDS             3269..4267
                     /locus_tag="LP468_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2082074.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4379..4888
                     /locus_tag="LP468_002604"
     CDS             4379..4888
                     /locus_tag="LP468_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL2082075.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
BASE COUNT         1571 a          924 c          860 g         1596 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat tgtttcctcc taatatttgc atacttcata ataataataa cataatacct
     3121 aacctctcgt aaaaatacta gatttgtttt cttttatttt tcatcactag atacattcta
     3181 taacttaccg tttcgatttc gaattcaaac atttttgaga agcattctca attaaattct
     3241 gctatagtgt gaaaagggag gaatttttat ggaaatctat gacattacaa tcatcggtgc
     3301 aggtcctgta gggatgtttg ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat
     3361 cattgacagt ctacctcaac ttggtggtca attagcaact ttgtatcccg aaaaatatat
     3421 ttacgatatt cctgggtatc cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa
     3481 acaattaact acttttaacc atacattcca tttaaaagaa gaagttctct cgcttactcg
     3541 tgaagacgaa gttatcgaga ttactacaaa taaaggcatc cattattcca aagcagtcat
     3601 tttagcttta ggaaatggtt cattccagcc aagaaaattg aatttagata atgctgaatc
     3661 atttgaaaac cacggattgg attatttcgt gaatgatttg atgaagtatg ctggaaaaaa
     3721 agtcgctatt gctggaggtg gtgattctgc tatcgattgg acgttgatgt tagagcctat
     3781 tgcaagcgaa gtttacttga ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt
     3841 atcacgcttg aaatcttcat ctgtcaactt gcttactccc tatctcatcg atggattatc
     3901 aggcaataat ggggaactga cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat
     3961 tgatttgatg attgattctc tgatcgtcaa ttatggattc tcttctaatt tagaacatct
     4021 ttcttcttgg ggacttgata gtaccagaaa tgccattact gtaaaatcag atatgtctac
     4081 ttctattcca ggcgtttatg cagctggtga catctgtacc tatgaaggaa aagtgaaact
     4141 gattgctact gggctcggtg aagcacctac tgcagtgaac aacgctttac actatattaa
     4201 tccaaaggaa cgaactcagc ctggtcacag cacaagctta tacgataaaa atcttcgtcc
     4261 tagttgattt tttatatctc tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt
     4321 tttttcatgt tccgttaaca tgaaatagag aaagaaaaaa taaaggggga gcaataatat
     4381 ggtcgtcaaa actgagactt tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt
     4441 aactgtagaa gatatcgcac aacttgtcat gtttttacaa aaagactata tttctgattt
     4501 gactttggcg gattgtactg aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa
     4561 cgccattatc actggaatcc aattagatat attagcagaa aagaaaaaat tgatgagtcc
     4621 gttgcaacat attatcgaag atgacgaagg cctttacggt atcgatgaga tcctagcctt
     4681 gtcaatcgtg aatgtttacg gtacgatcgg ctttacgaat tatggttata tcgacaaggt
     4741 gaaacctggt attttaaaag aactaaacag ccacgatggc gttcatgtcc ataccttctt
     4801 agatgatatc gtcggagcga tcgccgctgc tgctgccagt cgattagcac acaaagaacc
     4861 agaaaaaaga agtcgcctta ctcaataatt caacaaaaaa agaaagaaaa cgtctattta
     4921 gacgagttct ttcttttttg tttgtttcaa g
//
LOCUS       DAFEML010000112         4948 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFEML010000112
VERSION     DAFEML010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.115"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(459..884)
                     /locus_tag="LP468_002605"
     CDS             complement(459..884)
                     /locus_tag="LP468_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082076.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1258..2229
                     /locus_tag="LP468_002606"
     CDS             1258..2229
                     /locus_tag="LP468_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2082077.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2261..3658
                     /locus_tag="LP468_002607"
     CDS             2261..3658
                     /locus_tag="LP468_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2082078.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3817..4440
                     /locus_tag="LP468_002608"
     CDS             3817..4440
                     /locus_tag="LP468_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082079.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1708 a          811 c         1018 g         1411 t
ORIGIN      
        1 aattactacg tgatgtagaa taagcctttc tatcgtttgg ttattttata ttcaaatatt
       61 tgaaataaat aaatctttac tctttgattt gtaaactgaa atgatccact gtttgtttta
      121 ctgatgaagc ttgatcaaag gaagaagctg agtttgaagt tcataaaaat cagccatagt
      181 gagttttgct tggatttgtt tatcttcttc tactttttac ataattttga acaggataag
      241 attcaaatgt tttaaatgaa tctttgacta gtttgtgaca gttgtcgcat atgctcaagc
      301 ttccttggtc attaaattct gtatggatat ttttgttgtt attacatgta caataatcag
      361 gactatcgat catccatttc gtctccttta caatcatctt gcttctttac tatagcagaa
      421 aagaagggga gaaacaaaag aagatccaac agacggcact atagactgta gatgttgcca
      481 tcctcatcct tcaaacggta attaccgatt tttgtaaata tgactgttgt ttctttttta
      541 ttttcttttc ctgaaataat atattcgtca tctttggtag tgatcttgat atctgtcagc
      601 actgtttttt cttcagatga ttcagaagaa tcagttcctt gtgtctgata cgtgcgtgtc
      661 cattccattt ttttatctgt aaatgtcaac tgtcccgcgg ataaatccat atctttacgt
      721 acttttagcg tatatacact gttggtggta tctgcttttt ccgcttttaa gacagaagaa
      781 tcggttgttt cgtccgagga ttggtcagag ccgccaaaca aatcacagcc agtcaatgtc
      841 aaaagtcccg cagacaaaat aaatagtacg attaatttct tcaaaatact tcccccattt
      901 gataggataa agaaattata ccattggaat gtaaaacttc aaacggatgg aagagaaaaa
      961 cgcacaaaac acccacaaat agagtaaatt ttagaataaa attttaaaaa ggcaaaaaat
     1021 ccgccacttt cagaaagcgt tttaaaaaag tgttgcaatc ttttaaaaaa atgctatatt
     1081 aaaaatgaac cggttcaaat acttgtttaa gtataattaa tagtgagagg aagttgctct
     1141 actgaagact ttagttatat ggatattgat gacaagcaac actatgcaaa gaatgcggtc
     1201 atcataatcg aacaacaaga aagagaaatc aaatgtaact ggcaggagtg agaatgtatg
     1261 gcatcgatcc gtgatgtggc taagatggct ggtgtttcag tgggaacagt ttcccgttac
     1321 ttgaatggtc agcaactgaa ggaaaagaac atgaaaaaaa tagcagaagc gatttcagcg
     1381 ttggactata aagaaaacat cattgctaaa gggttgaaga ataatcgaag cttctctatt
     1441 ggacttttga taaacgggat ttccagccgt tttgggtcgg aagttgtctc agggatcgaa
     1501 agagtagctg aagaaaatgg gtatagctta ttattaagcg ggtttgccga tcagccagaa
     1561 aaaattgaac aaaaaattga atacctgatg aagcatgtga tcgatgggct gattgtcttc
     1621 ttatccgaag aagagtggtc tggatttgaa atgctcacaa aaatgagtat tccagttatc
     1681 gcattgaatt gtccagaagg accagcaggt attgatacaa tattagtgaa tgatcgagaa
     1741 agtgtagcaa aagtgatcgc tcatcatggt gaacaaggac ataaaaaaat cggatttatt
     1801 gctgccactc aaacagacta cgtagcaaga gaacgtttag caggagccaa agaagcggtc
     1861 caaaatgatc catcgatcca attagaggtc tttacaggag actattctag aaaaagcggc
     1921 tattacgggg caaaagcatt attagaaaaa ggggcaactg ctatttttgt cagcaattac
     1981 aatatgtcga ttggtgccat cgaatgtttc aatcaagaag gtgtcagaat cgggaaggat
     2041 attgcgttca gtcactatga ttatttagat aaaaacgatc tgagtatcct tccgaaaatc
     2101 acgatcacgc caccaacaga taaaatcggg gaacgagcag cagaacagct gttaaaacga
     2161 atcaaaaaag aagaggaaga aaatgaaaaa gtgattgtga tggaaaatat catacatgga
     2221 atcaactaaa acgaactaaa aaagaaaaag aggtgctttg atgaaaaaat atcaatttcc
     2281 agcaaatttt tggtggggtt ctgcagcaag tggcccacaa acagaaggaa ggatttcagg
     2341 cgatggaaaa ggagagaaca tttttgatta ttggtacaaa aaagaaccgc aaaagttctt
     2401 tgatcaagta ggacctgaaa aaacctcgca agtttatacg aagtatcaag aggatgtaca
     2461 gttgatgaaa cagactgggc ataattcatt tcgaacatct atccaatgga gccgtttgat
     2521 acctgatgaa tctggaacaa tcaacgaaga agccgttcgt ttctatcatc gttattttga
     2581 tgagttgatt gaaaacggta tcgaaccctt tgtgaatctg tatcatttcg atatgccgat
     2641 gtatctgcaa gaaaaaggcg gatggttgaa ccgagaaacg gttgaagcct atgaaaaata
     2701 tgccaaaagt tgttttgaat tgtttggttc gaaagtaaaa aaatggttta ctcataatga
     2761 accaatcgtt ccagtcgaag caggttattt atatcgatgg cattatccag aagagtcaga
     2821 tatgaaaaaa gcgatccaag ttggctatca tgaagcgttg gcttcagcgt tagccatcaa
     2881 atcttaccat gaaatggagc aaggtggtgt tattggtatc atcttgaatc tgacaccaag
     2941 ctatccaaga gacgaatcaa accctgaaga tgttaaagca gcgcaaatag cagatgcgtt
     3001 cttcaatcgt tcattccttg atccagctgt aaaaggcgag tttccaagtg aattgattga
     3061 gatagtaaaa gaacttgatc tcatgcctgt gatccatgca gaggatttga cggttatcaa
     3121 agaaaataca gtagatcttt taggtatcaa ttattaccag ccacgccggg taaaagcaaa
     3181 agaaacacca atcgatacta aaaacggtcc aatgcctgag gattatttcg acaattatga
     3241 aatgcctggt cgtaaaatga atccttatcg cggatgggag atctatgaac aaggaatcta
     3301 tgatattttg atcaatgtac gagatcatta tggaaatatc gactgcttta tttctgaaaa
     3361 cggtatgggt gtagaaaacg aagcacgatt tatcaaagaa gatggcatga tccacgatga
     3421 ttatcggatc gaatttgtcc aatctcatct gaaatatgtc catcaagcca ttcaagaagg
     3481 tgccaattgt ttaggctatc atatgtggac atgtatggat aactggtcgt ggaccaatgc
     3541 atataagaat cgatatggct ttatttcagt agacttagca caagatggaa aaagaacaat
     3601 caaaaaatcg ggtcattggt tcaaagacgt atcagataaa aacggatttg aggcttaaga
     3661 aagaatagtt gagagcaaat gcgtgaaatt ctccattctt accattttgt gaaaaagaag
     3721 ttcaattatt tacgatcttt ttcaactttt ttgtctttct atttcatttt ttgtatataa
     3781 tagaatagtc aaaattaaat aggagtggag gaaagcatga ggaaaaaaag accgtttctt
     3841 ctcttttggt tattcggttt tttcttactg cttattttat ccgcagcatt ttcaggaaaa
     3901 atgacagcag atcttgctca gaaagaaaca gaaaaaatcg tagcaagcaa agaatcagta
     3961 gataatttca aaaaagaatt ctcaacttat tggtgggcgg agtataaaat aactgccaat
     4021 tacgaaaaag gcgaattgga catttatttg ccaaaaggaa aagaagaaaa tcaatttatt
     4081 aatatcgatg acgtacttag tgcgatttct ctcagacaat atcaatttaa agacaagcat
     4141 ttgaccgttt tgcttttgac tcatgatggc gacaaagtag cccgtttgaa aaatggaaaa
     4201 gtgatcaccg cttattctga aaaagtagac aaaaaagtgg tcgccgatcg tttagcggaa
     4261 tggaaaaaga caaatgaaca agtcaagaaa acaactgtct cttctcaaaa aaacgagtcg
     4321 acaggaacaa gtccttcaga ttctggcagt ggacaaacga taacgggaag tgaagaaaat
     4381 caagcctcaa ttattacgaa tgagtcatca caaggacaat atcaatccta tggacaatga
     4441 aaaacagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa acggcaaaat
     4501 agttcctcat attttgccgt tttttgagct aataccgaag gtcagctgat tgaacaccgt
     4561 gtatcaagag gtcttgagcc tgccgtttaa ctctgagcca caaggagcaa tttcaaaaaa
     4621 tagctcctta tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac
     4681 cgtttaccaa gaggttgtaa aattagcgtc ctgacataat ctaataccga gggtcagctg
     4741 attgaacacc gtgtatcaag aggtcttgag cctgccgttt aactctgagc cacaaggaac
     4801 aatttcaaaa aacagcttct catgttttat aaatattgtg acttgtggcc gaggagttgg
     4861 caggagaaca ccgtttaagg aagaagttgt gaaaaagctg tcctgcatca agaaataagg
     4921 agctgcgaca agaattttgt cacagcct
//
LOCUS       DAFEML010000113         4811 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFEML010000113
VERSION     DAFEML010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.116"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(1..657)
                     /locus_tag="LP468_002609"
                     /pseudo
     CDS             complement(1..657)
                     /locus_tag="LP468_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(692..2305)
                     /locus_tag="LP468_002610"
     CDS             complement(692..2305)
                     /locus_tag="LP468_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2082080.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            complement(2417..2626)
                     /locus_tag="LP468_002611"
     CDS             complement(2417..2626)
                     /locus_tag="LP468_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL2082081.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            complement(3615..4811)
                     /locus_tag="LP468_002612"
     CDS             complement(3615..4811)
                     /locus_tag="LP468_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL2082082.1"
                     /translation="MEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQPLNDELR
                     EIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDYGKYGYE
                     SKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMTAGGVMK
                     RLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTGETLYLG
                     STSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLTYRDAER
                     TAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTLQKALHW
                     LQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERIDTAVPQ
                     ENDGIF"
BASE COUNT         1304 a         1062 c          778 g         1667 t
ORIGIN      
        1 tttcgcaatc catgcaagat ttggatcaat gtgtcttaat aggaattcta acgattgaat
       61 cacccctgta ttaagagaca aaccatgttg aggtactgta gtagcgacgg tcaatccgcc
      121 aaaagtatct aaaatgattg ccagaataac caatacaaac attgctaatg gataatcctt
      181 tttagggttt tccatttcat ttgcatgact ggcagatgtt tctacgccca tatatgctaa
      241 aataaaggaa acaaaaacaa ccagcgtagg caatttcgaa aaatcaggaa tcaatgtttt
      301 catagacagt atcgtttgta gtggagcgcc tgaagcgaca taatggatcc ctaagccaaa
      361 caagactaat gctggcaaca agataccagc tacaaaaccg atccgagcaa tcaatgaagt
      421 gtatttggtt ccttttaact gtgagagtaa aatagcccag aaaataatca ataggattgc
      481 caatttcaga tatttattgt tttgtatagc accaataccc gttgcatagg ataatgcacc
      541 agttaagaaa tacagcatgg tcaagtagcc aactgttatc tcaaaccatt ggaaaaagat
      601 tgcggcaaaa ccgaatcgtt ttcccaatgt gcgactgacc caagtataga caccgccggt
      661 ttcccttagt taaaaatatt actcttgttg attactcaac tcttccaata aatcggtaat
      721 atatctcaat ttcctgtatt ctttcgttat cctcattcgt tgttgcttca tgtatgagga
      781 ttttttctat catggcattt aataatggtg ctgtcagttc ctttggtacg gaatattcct
      841 tgattaactc aatccacttt tcagcaccta tcatatcctg ttccatttta cttagttctt
      901 ctcttaggct tgttatctgc tgttccagtt ctatctgttc tttttggtac ttgctggaca
      961 acatcacaaa atttcgctct gttatcttct cacaggctct atcttcatac attttcgcaa
     1021 ataaacggtc aatctcattt tgtctgttct cggctttctt caatgtactt gcctttttct
     1081 tcttttcccg tattctctct gcattgccag ctttctgtat cttgttcaat accttttctt
     1141 cgtcctgctg tactgcctta gcccaatact gcaagcgttc caatacggct tgatacagca
     1201 catcataacg aatgtagtgc atagaacaat tacctttgcc aaactgcccg tagtaactgc
     1261 aagcataata actgtaaggc gttttatttg tcttattcgt tccaaatctc atagaccaac
     1321 cacaatccgc acacttgaca agccctgcaa aaatcggcgt tgccttttcc tttgtctgtc
     1381 tgcgtcttga ttttatctgc tcctgcacac gatagaacac ttccttgtca ataatcggct
     1441 cgtgagtgtt ttctactcga aaccattcac tttcgggctt acgcactttc tttttgctct
     1501 tgaacgatac cgtagactgc atattgtgaa cactgtttcc gatataaacc tcacttttca
     1561 atatcgcctt gacatgagca atcgtccact cataacgctt actttcgggt tttccctcaa
     1621 agatatgtgc aaaagtaccg tatcttgtaa aatttagcca tgacgctgtc ggaacttttt
     1681 ctgctcttaa ctgctttgtg atttttgcac ttccgtaacc ttgataggct agggaaaaga
     1741 ttttttcaat aatccatttt gtttcatcat caaccaacag ttttcctttg atgtcagggt
     1801 gtttcttata tcctaacgga gcataagcac cgtaatgagc cccctccgca aactttgtct
     1861 taaatgctga tttgacttta cggcttgtat ctcttgccac ccattcattg atgatgttct
     1921 taaatggtgc aatctcactt tcgccttttt cgctgtctac accgtcatca atcgctatgt
     1981 agcggacatt atgactaggg aaatacaatt ctgtatattg tcctgtcata atataatttc
     2041 tgccaagacg ggaaaggtct ttcgttacaa cacagttgat ttttcctgcc tctatatcct
     2101 caatcattct ttgaaaactc ggtctgtcaa aatttgttcc cgaccagccg tcatcaatat
     2161 attcatcaat gacattcaaa tgatgttctt ttgcatataa acgcaacata cttctctgtg
     2221 tggtaatgct ggaactttcg ccctgtaatt catcatctcg gcttaaccta agataaagtg
     2281 cagtattgta aatctgttgt ttcattgtca gttatcctcc tttataacta acccgtgttt
     2341 acaatacctg cttgcaagta aagtataaca cgggtacttt ttgtcattca atctatttct
     2401 tacaactgca ccgattttat gcgattgtct gctttgcttt ttccagcatg acatcagtta
     2461 gaagttcttc cattgttttg cccttttcgg aaaaatgctc ttttactaca atctttgtct
     2521 ttcctctgtt gccaatgcca cacttgccat ttttcttttg aattgttttt acagcattat
     2581 caataacaca tacccccttt ctgtaaaatc tttctaagca attcaacggc ttttgtcata
     2641 gcccacagga gttccacctc tgcatagttc ttatgtagcc gtacccattg cgtgcgacgc
     2701 tcttaatgct caagctgtgg ctgtacggga gtatcattat ctgacagtac aggtcatggc
     2761 gataaaagag gacaaatctt ttacaagaac acaaataggt tttcgctcgc tcttgcaggg
     2821 gaaaggtcgt ggcgtatttg tttcaacggc tagctgtctg tcaaacgtat tgaatagctt
     2881 tattcagttg tcaaagaacg attgaaagaa aaaaatcgtc tttcctatat atcgcgttgg
     2941 aaaagaggag aaacgtaacc aaaatccaaa actttttcca ttattagtac aaatggaacg
     3001 gttcattttg gcaatcaacg gttgattttc tcctttttca ctactatctg tacagcaaac
     3061 gtccatttgc taagtttaaa tggaaaaatt ttaacttctt ttcatgcacc atatagggat
     3121 agaaaatgtc attttgctaa gttgatgatg aaaaaagaat attttccttt tcacacccta
     3181 actacccaaa ccataccgtt actgccaaca atagaatgaa atattttctt tgcaccatat
     3241 agggaacgga aaccttaaat tgttaagttg agaacaaagt attttcatct tttcacatca
     3301 acactcaact gctaatgcct gtttgaatac aaaatgatga tgtttttcct cttttcacag
     3361 aagactgtcc actaatcacg aatttccgtc attttttcaa aacttttttc ttctttcact
     3421 tcatataggg acagcaagcc ccgatttaat gacctatttt caaaaaaagt ttagatttcc
     3481 ttttctcgca ccatatctgt acgcaagtag ccattttgtt gcagatttaa taaaaaattt
     3541 atttttcttc tttcacttca catagggaat gaaaacagct ctttgctgac taaatctgaa
     3601 atttttcaat tacattaaaa aataccgtca ttctcttgtg gaacagcggt atctatacgt
     3661 tcttctatgg ttgatttctc taattgtaat aaatgtttat gcttgtcttt tagttctgcc
     3721 tgctcaatca tatctttcag tatcgttgta cgattttctc tgtctaatgc ctgtaccatt
     3781 tttatggttg gtgcgacttg tctttgtagc caatgcaacg ctttttgtaa agtgtaaggc
     3841 tctggctttg tggttaagcg tatcggctct ctgttttccc ctacaaacca tgcccaatca
     3901 tcatttgtta tccattgact ttttggcttg tcgtcctctc tgtcaacaaa gcggacataa
     3961 tgattgatga tagaaaaagc ggtgcgttca gcgtcccgat aggtcagtaa atctacaacc
     4021 gcataatagg ctcgttcgtt cttcatgcgt atttcaaaac ggttcttaat ctccgtatct
     4081 tcaatttctg tgccattctt gacatactgc tcataatttt tctgataagc acacatatat
     4141 aattcgctac ttgttgaacc gagatataag gtttctcctg tattctttgg taaatcgcta
     4201 ccgcattttt ctgtaccgct gtaatctttc tgcatacgga agtaggacat acattcgcca
     4261 gccttgtatt tttcctttaa ctttggaata tccaatattc ctgctttatc attgatagcc
     4321 aaatcaagcc gtttcatcac accaccagcc gtcatacaat ccagcatgaa gtcataccat
     4381 gagcgttcct gtgccagcag ataacattcc atttgccgac agcctttgcc tttcagttcc
     4441 aataaaacac ctaaatgctc ctgcatggaa cacatgatat tgatgtcgcc aagtacatat
     4501 ttgctttcat atccgtattt tccataatct tcataaagca tgtaattaga tttcagttgt
     4561 aatacatcac ggataatcgc caatgcgtcc gtagtaggaa agcggacacg aaagtaatca
     4621 atcaataaga atagtggttc ttgcggattg aaacgctcaa tctgtttttc tatgatttct
     4681 cttaattcgt cattcaatgg ctgttttcct ttttcaatgc ggttgtaata ttcacggctg
     4741 ataccacagg caacagcaag ccttgtttgt gttactccgt attcctcacg cttttgtctt
     4801 agttcttcaa t
//
LOCUS       DAFEML010000114         4807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFEML010000114
VERSION     DAFEML010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.117"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP468_002613"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP468_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL2082083.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LP468_002614"
     CDS             complement(3250..3768)
                     /locus_tag="LP468_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL2082084.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1712 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DAFEML010000115         4767 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFEML010000115
VERSION     DAFEML010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.118"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..196)
                     /locus_tag="LP468_002615"
     rRNA            complement(<1..196)
                     /locus_tag="LP468_002615"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(882..2387)
                     /locus_tag="LP468_002616"
     CDS             complement(882..2387)
                     /locus_tag="LP468_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2082085.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2384..3070)
                     /locus_tag="LP468_002617"
     CDS             complement(2384..3070)
                     /locus_tag="LP468_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2082086.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP468_002618"
     CDS             complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP468_002618"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL2082087.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1315 a          996 c          800 g         1656 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aatgtttgtt gtcttgaatt gaatcaagac gccctacaca
      301 tttggtttgt cttactttgt tcagttttca aaggtctaat ctttttgttt taacaactct
      361 ttaatcttat cagattcaga agagaatgtc aacaacttct ttgtttattt tttctaaacg
      421 tctttgccac tcattagcag cgacttgatt atcataccat ctttattgtt atttgtcaat
      481 aactttttcg aagttttttt cgataaaatc aagctttatt agctatctca tccaaacgac
      541 ttcgttatta taacatgaca tcaaaagtgc gtcaacacta ttttttataa tttttagtga
      601 caccttaaag gaatcattta gaacaaataa taatatagca atctctttat aaaattgcaa
      661 tagaaaattc cctattttta tttattattt ttaaacacga atattacagc attttattgt
      721 tttttcgttc atctaaaaga tacttacatt taattaacgg atgttattct atttaattgt
      781 tcgctagttt ttttataatg acatccctga atttctcact tgcttgtatt ttgtacctta
      841 ttctttgttg gatatataaa aaaacaagta aagcacatgc tttacttgtc ttctgccttt
      901 gcgataggaa taaagattct aaaaattgtc ccttgcccta ctacactttc tgctaagata
      961 cgtcctttat agttttcaac cagttgttta gcgatagaca accccagacc atttccaccc
     1021 ttcgttctag ctcttgcttt atccactcga taaaaacgat tgaagatctt attaaggtct
     1081 tctttgggta ttccttcgcc aaagtcctga atcgcgatct caaattcatt cagagtggaa
     1141 gaaatagaga tatggacttc ttttcgtgta gttgaatact ttactgcgtt atccaatatg
     1201 ataatgatta attgttcaaa gtgattacga taaatttgca gggtcacttc ttttgtcaaa
     1261 tcatcatcta aagtgatcac atagtctgga tataatatct tgaaattatt ataaacttga
     1321 taggtgactt cttttccttt agttgtttca ttcgcataat gaacatctac ttgttctgct
     1381 cttgataagt ctagcatctc ttgaactaag cttttcatac ggctgatttc ttgcatgctg
     1441 gcgcttaatg attcttctaa tatctcagga tcatctttcc cccaacgatt tagcagacta
     1501 agatgccctt caataattgc aacaggtgtc cttaactcat gagatacgtc ttccacgaat
     1561 tgctcttgtt gttcaatata caaacgcata cggtcaagca tctcattgaa tatttcagct
     1621 aaatctgcca attcatcatt tgtgtcgatt tcaggcatgt ggatatctga ttgcggatct
     1681 ttacgtatag tatccattgt atctctgagt accttgagtg gttttaagaa ataagaagat
     1741 aaaaagaaac ctaaaatact acttaagatc aaagaaacaa cttctaaaac aataagagtc
     1801 aataatagct tatttcgaat atcatagaaa gaagataatt catagaagct ttgcgcatag
     1861 ccgatctttt ctcttgtacc tttagaatat ataggctgga tagataaaaa gccagttttt
     1921 ccttctagtg taacgatcgt tggaacttta cgtgtagtct gaatcaggtt tcgactgttt
     1981 tcatgggttt taaaaatcaa gttctcgtcc aaatcataaa cataaagatc cattgatggc
     2041 tgccctagct cagctataaa ggaatcgatc ttcattaagt ttccttcgac cagtgaagta
     2101 tgatctacga cctcatctcc gtcatttgtc gctttcgtca gattacgata cgtatttact
     2161 aatgtcagtt cttcatccga gttagccaaa cgagaagcta cttctgaaat cgtacgctct
     2221 acattgtttc tttcttttgc cacaatcaga ttgatagatg atttataggt aatgacagcg
     2281 aaaattgtaa acacaacgaa tatgaagaaa gaactcgcaa aggcccactt gattgtcaag
     2341 gagggccctt tcagttctct tttttccgat tttttcggct ttatcacgag cgcatcacat
     2401 aacctgttcc gcgtacagtt tggatatagc tttcctcccc gggaacgtca attttgttgc
     2461 gaagataacg aatatatacg tccactacgt ttgtttcaac ttctgtttcg tatccccaca
     2521 ctttatttag taaaacgtca cgtgctaata ccacgttcac gttttccatt aaagtaagca
     2581 gcaactcgta ttctcttttt gttagttcaa ttacttcatt tccgcgacgt acgacacggt
     2641 tttctttttc gatagtcaaa tcgcgataag taatagtagt ttgtttagcc acatttttat
     2701 cgccttcaat atcgattcga cgcaacaatg cacgaagacg tgctaataat tcttcgatag
     2761 caaatggttt gacgatgtag tcatctgctc cgtggtcaag tccagataca cgatcgatca
     2821 cagaatctct tgcagtcatc ataatgattg gtgtattttt gacttggcgt acacgtctgc
     2881 agacttctaa accgttcaat tctgggagca tcagatccaa caatatggca tcccactcat
     2941 tatttaatgc cgcatctaaa ccagttcggc cgttgtagtg gacttctgcg ttataccctt
     3001 catgcttcaa ctctagctcg acaaatcgtg ccaagttctt ttcatcttca atgattagaa
     3061 tattgctcat ttattatttt atcctttcta ttctactggc tttttaaaaa ctctatcatt
     3121 ataccgataa tatgcttaaa aatctatagt cattttatca tggatagcaa ttttaaaaaa
     3181 gagctgaagt ctactcataa caatcgactt cagctctttc gtcctctttt tattttctca
     3241 tttcctaaca gccgaaagac tattattctt catggtacca tgagtaatgg aagattcctt
     3301 ctttgtcgac acgctcatag gtatgtgcgc caaagtaatc gcgttgggct tggattatat
     3361 ttgcaggcag acgttctgct ctgtatgaat cgaagtaagc gatggctgat gagaaagtcg
     3421 gtacaggtac gccagcttgg acagccaagg caacgacgtc tctgactgat tgctgatatt
     3481 ttttcgtgat ttcaacgaag taatcatcta gcaataaatt ttcgatctca ggatttttgt
     3541 cataggcatc cgtaattttt tgcaagaatc gagctcggat gatacatcca gcgcgccaga
     3601 tttttgcgat ttcaccaaat ggcaagtccc aatcaaattc ttttgaagcg acacgtaatt
     3661 gagcaaatcc ttgggcataa ctcatgattt tactgaaata caacgcttct cggatttttt
     3721 cgaccaattc ttttttgtct cccgtgaact caaaatcgtt cgtacgagac aaaatcttgc
     3781 ttgcttgtac gcgttcttct ttataagcag aaatatagcg ggcaaataca gattcagtga
     3841 tcaatggaag tggcacacct aagtcaagcg cgctttggct tgtccattta cctgttcctt
     3901 tattcccagc tgcatcaagg atcacatcta ctactggttt acctgttcct tcatcgtctt
     3961 tacgtgtcag aatgtcagca gtgatttcta tcaaatagct gtctaattcg ccttgattcc
     4021 attctttaaa gatatcagcc atttcttcta ctgaaaggtt taaaatattc ttcattaagt
     4081 cataagattc agcaatcagt tgcatatctc catactcaat accgttgtgt accattttca
     4141 cataatgtcc ggctccattt gggccaatat atgtgacaca tggtgctccg tcttctgctt
     4201 ttgcagaaat ttgctctaag attggtgcaa ctagcgcata ggcttctttt tgtccaccag
     4261 gcatgattga aggtcctttt aaagctcctt cttcaccacc ggaaacgcct gtaccgataa
     4321 agttgatgcc agagttggct aactcttcat tacgacgcat cgtatcttta aagaatgtat
     4381 ttcctccgtc aatcaaaata tcgcctttat caaggtgagg aagtaactct tggattgttg
     4441 catctgttgc cggtcctgct ttgaccatta gcaagatccg acgtggtttc tcgatagatt
     4501 ctacaaattc ttcgattgta tatgttgctt tgaaattttt atctgggtgt tcttctacta
     4561 cagcggttgt tttagcccct gtacgattga ataaagccac tgaatagccg cggctttcta
     4621 tgttcaaggc tagattttta cccataacgg ccataccgac aacgccgatt tgttgttttg
     4681 acatatgaac tcctcctaca tacgggattt ctccctaatc tcttacatta tagcttaaca
     4741 cggctacatt gcaaactaaa gaacaac
//
LOCUS       DAFEML010000116         4743 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFEML010000116
VERSION     DAFEML010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.119"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="LP468_002619"
     CDS             <1..1350
                     /locus_tag="LP468_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2082088.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2815
                     /locus_tag="LP468_002620"
     CDS             1484..2815
                     /locus_tag="LP468_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2082089.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFIFSFVKLS"
     gene            complement(2802..3761)
                     /locus_tag="LP468_002621"
     CDS             complement(2802..3761)
                     /locus_tag="LP468_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2082090.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(4052..>4743)
                     /locus_tag="LP468_002622"
     CDS             complement(4052..>4743)
                     /locus_tag="LP468_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HBL2082091.1"
                     /translation="ATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVW
                     NELLQDIYSRGVHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKD
                     RKEICDDFKAVYQASSKEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGI
                     RRSIYSTNLIESFNKQIKKYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQ
                     VTDTLASMFTE"
BASE COUNT         1661 a          731 c          891 g         1460 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttttcgttt gtcaaattaa gttagacaaa
     2821 tcatcttttg tgacgtaact caaaaatact tccattggtg tccgatagtg taatgatttt
     2881 ctaggaatat gatttcgttt cgatgccacc gattggataa aggtttcaga tacaccatta
     2941 aaatccatag ctttatacaa accatcttta cgtaataagc catttgaatg ttcattcaat
     3001 cctcgttgag aaggtgttcc tggatccgca aaataaattg aaatatcgtt ggtattacta
     3061 atctttttcc aatttgagaa ttcttttcca caatcaaatg tgatggattt aaataagttt
     3121 tttgggacac aacgaaacca ttgattcagc ctattttcaa tgtctttagc ctgtctgcct
     3181 tcgggtttca aggtaatgat gactttagat agccgttcaa ctaatgtgat gaccgcgctt
     3241 ttatgttttc cacccacgat agtgtcacct tccaggtgac caaattcatg atcaaactgg
     3301 gtatagtctg tctttctgtc tcggattgac cggcgaaacc cttgttttcc tcttttttct
     3361 ttatgaccgt ttggttttct ttttcccttc attggtaaat cgtgagtgtc aaaggtttta
     3421 tctttaaaca ttcgatacag tgtgcgtacc gaacaagcaa taggaaactc tgctcgacca
     3481 ataaggacat caggagccca cccttgaaca accttttttt gaatgtattc ctgttgctca
     3541 tcaggtaaaa caatcggatg tcttccgcag ttacgtttgt ttttcttata ttgtttatag
     3601 tagctcattg cgcttccacc agatttaaga aaacgataga ccttataaat agtttgtcga
     3661 gaacgttgta acagattggc tacttttgaa acaggttgtg attgattgaa ataagcttct
     3721 atcattacga gttcagttgg tgtaagatgg ttataggtca tttgtactca ctccttataa
     3781 ttctttcgtc ggaactattt tgagtgtagc acaaatgact ttttttagtt gtctagctta
     3841 attttacaat cggcgtttta aaggcagtaa caggattaaa cattgaaaca taatcgttac
     3901 taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt atcataattt
     3961 ttaatagaaa acactattaa agagaaaaaa gagaggtaag ggagcgtcaa taattttgtg
     4021 taaataactc gtccttctgc aaaataatgg gttactcagt aaacattgaa gctaatgtat
     4081 ccgtcacttg ttggaagcct ttatggcttc tatttaagaa tttttgattg tatgtatcaa
     4141 agatggatac taggaaacgc tctagtgatt cttcattttg aaactgctct tttctgcggc
     4201 tgtatttctt gatttgttta ttgaaagatt cgattaaatt agttgagtaa atgcttcggc
     4261 ggataccagg cggaaactca taaaaagtca ataaatcttg attttttatc agtgactgcg
     4321 tcactttagg ataagttttc tgccacttct caatcatact ccctaaaaag gtatttgcct
     4381 cttcctttga gctagcttga taaacagcct taaaatcatc acagatttct tttcgatctt
     4441 tgacacgtac tttatgagca atattacggg aaacgtgaac acagcaatgt tggtatttag
     4501 ctttaggata aatctggtga atcgtatctt tcatgccttt taagccatcg gtaataaaca
     4561 gtaagacatc atgaacccct ctggagtaaa tgtcctgtaa caactcattc caaacgtagg
     4621 tcgattcagt cggggcaatc gcataactta gtacttcttt agtgccgtct tctcgtatac
     4681 caatggcaat atagattgct tctttggaga cggtttgccg ttttaaagga atataagtag
     4741 cat
//
LOCUS       DAFEML010000117         4734 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFEML010000117
VERSION     DAFEML010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.120"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            315..2159
                     /locus_tag="LP468_002623"
     CDS             315..2159
                     /locus_tag="LP468_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2082092.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSSTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            2215..3681
                     /locus_tag="LP468_002624"
     CDS             2215..3681
                     /locus_tag="LP468_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2082093.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            3718..4560
                     /locus_tag="LP468_002625"
     CDS             3718..4560
                     /locus_tag="LP468_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2082094.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         1541 a          761 c         1016 g         1416 t
ORIGIN      
        1 gttggaagat attcttagaa aaaagacaaa acttttagaa cacgaaaact atattgaacg
       61 aataaaatga aaaaatgatt aaaaaatcat tttattattt acgtttacat tctaatatgt
      121 taaattgaat ataacttaaa caggcatgtg actggtaatg caggcaggac ctaaataagt
      181 tgaataacaa tgtatgcgtt tcaatacacg tttgccttgt tgtcaattta tttagtttct
      241 gcctgttttt tgtgttgagg atggccactt cgactcaaaa gttcatcact caaaaaagaa
      301 aagagggaaa caccatgaat tacaaacaaa cagcagaaga agtattgcag tacatcggtg
      361 gggaagaaaa catatcccat ttggagcatt gctcaactcg tttacgtttt acgttaaaag
      421 acaacagcaa ggtaaatatg agccagttag aaaaagtgga tggcgttatg ggcgttcgcc
      481 aaaatgtgca atgccaagta atcattggaa acgatgttgt tgaagtgtat gatgaagtga
      541 aagcgttatt aggtgacaat gtttcaagta ctgaagaagc accaaaacaa aaacaaaaat
      601 taggttcagt tctattagat tttattattt ctattttcca acctttaatt cctgcgattg
      661 caggtggagg agtattgaag tccttgttgc tactagcttc tatcttaggg ctgattagtg
      721 accaatctca aacctatcag attttaaatt tggtcggcgg ggcaccgctt tatttcttgc
      781 ctattctggt ggcaatgact acggctaata aattgaaagt caatcaattg gttgcagtat
      841 ctgctgtcgg tgcattgatc cttcctgaaa tgacagctat gttggcggaa ggtgctacat
      901 tcttatcttt tggattggat aatatagcgt atgcatctca agtattccca gccatcttaa
      961 ctgttttatt ttatgctcaa cttgaaaaat ggtttacaaa agtttcacca aaaccaattc
     1021 gtattttctt tgtacctatg atgagtttat tgattacagt tcctattgct ttgttgcttc
     1081 taggaccatt aggttataat gtaggaacag ctttctcttc tatcattgtg tctttgtaca
     1141 atcaatttgg atgggttgca accggagtct tagcagctgt actgccatta atggttgtaa
     1201 cgggtatgca taaagcaatg atcccttacg ctgtttcatc catgagtgaa ttgggtgcag
     1261 aacttcttta tctcccggct tcattggcac acaatatttc agaagctggc gcatgctttg
     1321 ctgtcagtat caaaacaaaa gacaaaaaat tgaaatctac ggctgtttct gcgggtatat
     1381 ctgcattatt cggaattact gaaccagctc tttacggggt aacgattctg cacaaacgtg
     1441 ttttatatgc cgttatgttt tctagcctga tcgggggagc atttgcagga atcgttgcac
     1501 ttcaagcctt tgctttagtg ggtcctggga ttgcaagtat cacgatgttc gctgacaaag
     1561 ctgacccaat gaatctggtt tgggcatttg cagtatcggg gatttcattt gtggttgctt
     1621 ttgctgcagc gttggttctt tataaagata aagaagttgt caatgaagtt gaaactaaga
     1681 tggaaacggc cgttgtttca gatgctgttc tttcaagtcc cgtgaatgga aaagtaatct
     1741 cactatcaga agtaaaagac actgtttttt ctagtggtat ggtaggtgat ggagtagcaa
     1801 tcattcctga agaagggata ttagtagctc ctgaagatgg agaaatcaca atggtatttg
     1861 aaacgaagca tgctattggt ttaaaaacgg ctaatggtgc agaacttctt tttcatattg
     1921 gtattgatac tgttcagtta gaaggaaaag ggtttgaggc atttgttcgt tctggtgaaa
     1981 aagtagccaa aggacaaaag ctgattgcat ttgatattga tttaatcaaa gaagcaggat
     2041 tcgaccccac agttatctgt gtggtaacca ataaggataa ttacactatc cgttcattta
     2101 acctagaaaa attggtaacc aatgatagtg atctcttagc tatcagtccg atagcttaaa
     2161 cacaagatag tgaaaaaaaa tatattgaat gaaggaatag aggagaatag aataatgaca
     2221 aacacaacaa gttttccaaa aggattttta tggggcggcg cgatagcagc aaatcaagta
     2281 gaaggtgctt ggaatgtaga cggtaaaggt ctttcagtag cggatatggc tacttataaa
     2341 ccaaatttag acaacaaaga ttttgctgct catatgcatg tcaccctgca gtctataaaa
     2401 gaagctagtg aagacaaatc tgataaatgg tacccaaaaa gaaggggcgt tgatttttat
     2461 catcactata aagaagattt agctttattt gccgaaatgg gctttaaaac cttgcgcctc
     2521 tctattgctt ggactcgctt gttccctaca ggagaagagc tggaaccgaa tgaaaaaggg
     2581 gttgcatttt atgaaaacgt ctttaaagaa atgcaacgtt taggaattga gccgattgtg
     2641 acactatctc attatgaaat gccattagct ttagcagtta aatataatgg ctgggtggag
     2701 cgtcgagtaa ttgatgattt tgttcgcttc gctaacgttt gttttgatcg cttcggcaaa
     2761 tacgtaaaat attggctgac atttaatgag atagacagca tccaccgtca tccatttaca
     2821 acagctggaa ttatccaaga gaaaagcgca gaaggtcaag aagctcaaga tatctatcaa
     2881 gcattgcatc atcaatttgt tgcgagtgcg ttagtgacaa aagatgctca tgaaaaaatt
     2941 ccaggaagcc aagttggttg tatgttaacg aaattgatga cttatccatt aacttgcgca
     3001 ccagaagacg ttgagctgac cttgaaaaag aacttagaaa ataattttta tgcagatgtt
     3061 caagttaagg gagaatatcc tgctctaatc gaaaaggatt tggaaaatcg gggaattcag
     3121 attaaaatgg aagatgaaga tcgagaaatt ttaaagaaac ataccgtaga ttttgtttct
     3181 ttcagctatt acatgtccat ggcagaatca gctgatccaa acgcagaacg cacaccggga
     3241 aatactgttt taggggttaa gaatcctcat ttgccttcaa cagattgggg ctggcaaatc
     3301 gatccaaaag gtttgaaaat ttcgttgatc gaactttatg atcgttacca agtaccgttg
     3361 atgattgtgg aaaatggtat gggagcagtc gatcaggtag tagatggtaa aatccatgat
     3421 ccgtaccgca tcgactactt taaagcacac ttccaacaaa tgaaagaagc aatcgatgaa
     3481 ggtgtagatt tgatagctta tactagctgg ggaccaattg atttagttag tgcaggaact
     3541 tctcaaatgt ctaaacgata tggatttatt tatgtggatg cagacgatga aggaaatggg
     3601 acatataacc gcttgaaaaa ggattcgttc aactggtaca aagaagtgat cgaaacaaac
     3661 ggtgcatcct tattcgagta gtctcgatct ttttaagcag cgataggggg ataatgagtg
     3721 atttcaataa aaaaagtatt gaattcaagt gtggtactgg ttgaagaaaa tggcaaagaa
     3781 atgattgcat taggtaaagg gataggcttt ggacagaaag ctggggatga aatatcagga
     3841 gataaagtag ataaaatatt tctgcctttt gaagaaaaga aatcttcaca actattagag
     3901 ttagttgaag aaatacctat tgaatttttt gaaatcactc gtactatcgt ttttgaagca
     3961 gaaaaaggat tagataaaaa actgaatcct ggagtctatt taaccttaac agaccacctg
     4021 cattttgcag ttgaacgcgc acaaaaaggg gtaaatattg caaaccgttt gtactgggaa
     4081 ataaaaatct actatcccaa agaatttcaa attgggaagt acgcactcac ccttttgaac
     4141 gagcaatatg gaattgatct tcctaaagag gaagcctcaa acattgcttt ccatttgatc
     4201 aatgcacaat cggaagatcc tgatagcggc gctggattca agtatgcaaa aatgatcggc
     4261 gggatcgtca atttggtccg gtattcgttg cagaaagata tcgatactaa ttcgatccat
     4321 tatgcccgct tcattacaca tgtacgtttc tttgtagaaa gatattattc tgatgctttg
     4381 ttggatgatg gtgaggaaga attctacaat caaatgtgga tcttataccc gtctgccatg
     4441 gaaagcgcag ctaagatcaa agactacatt gaaaaagttt atcataaaac aattccgaac
     4501 gatgaagttg tatacctagg tgtccacatc aatcggttga tgaaacatgc taatgggtga
     4561 gcgctcagta atactattga tgcttttaaa atctttagag atggattata gtaaaaacaa
     4621 ggtgatttcc agctgtttgt tatctataag agacatttaa aaaggattaa cgtaagataa
     4681 taaaaaatct cggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DAFEML010000118         4616 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFEML010000118
VERSION     DAFEML010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.121"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(15..962)
                     /locus_tag="LP468_002626"
     CDS             complement(15..962)
                     /locus_tag="LP468_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL2082095.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LP468_002627"
     CDS             complement(1140..1943)
                     /locus_tag="LP468_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL2082096.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LP468_002628"
     CDS             2089..3003
                     /locus_tag="LP468_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2082097.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LP468_002629"
     CDS             3051..3521
                     /locus_tag="LP468_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL2082098.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LP468_002630"
     CDS             3606..4214
                     /locus_tag="LP468_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL2082099.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LP468_002631"
     CDS             4348..4548
                     /locus_tag="LP468_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2082100.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1511 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttag
//
LOCUS       DAFEML010000119         4505 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFEML010000119
VERSION     DAFEML010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.123"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            175..519
                     /locus_tag="LP468_002632"
     CDS             175..519
                     /locus_tag="LP468_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL2082101.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="LP468_002633"
     CDS             520..939
                     /locus_tag="LP468_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBL2082102.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="LP468_002634"
     CDS             complement(1031..1381)
                     /locus_tag="LP468_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082103.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="LP468_002635"
     CDS             complement(1347..2678)
                     /locus_tag="LP468_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL2082104.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="LP468_002636"
     CDS             2934..3500
                     /locus_tag="LP468_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2082105.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="LP468_002637"
     tRNA            3645..3732
                     /locus_tag="LP468_002637"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            4066..>4505
                     /locus_tag="LP468_002638"
     CDS             4066..>4505
                     /locus_tag="LP468_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBL2082106.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKE"
BASE COUNT         1641 a          759 c          869 g         1236 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatcaa cgattagagg ttgtgaagaa gctgtcctgc atcaagtaat
     3781 aagaacggcc aaacaaaaat agcttttcct attttttcgt ttgattgggc ttattaccgc
     3841 agatgcaagc ttttgaacac cgtttgttcg gaataagggg ctgtgacaag acttttgtca
     3901 cagcccctta ttgttgtact tttaacctac aatatttttt gattccccct gagtactatt
     3961 ttttataaat gctagtaaat caatcttctt tggccttttt ttgataaaaa aaatactaga
     4021 tgtaagataa aagtgtaaaa acgatttgtt ttaggagggg aaacgatgtg taccgcaatc
     4081 acttatgcaa cgaaagacca ttattttgga aggaattttg attatgagat gtcttataat
     4141 gaagtggtca ctattactcc aagaaattat cgtttcgatt ttagaaaggt aaaaaattta
     4201 gataaacatt atgcaatgat aggaatagca gctggggtat ccaactatcc actctattat
     4261 gaggctacaa atgaaaaagg gttgagtatg gcaggactga attttcctgg caatgctgat
     4321 tataaagaat tacaagaagg aaaagataac gttgcaccat ttgagtttat tccatggata
     4381 ctagggcaat gctcaaccat agacgaagct aaagaattat tggctactat caatctagtc
     4441 aatatcgatt ttagtgaaaa actacccttg tcacctttac actggttatt agctgataaa
     4501 gaaaa
//
LOCUS       DAFEML010000120         4418 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFEML010000120
VERSION     DAFEML010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.125"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            61..915
                     /locus_tag="LP468_002639"
     CDS             61..915
                     /locus_tag="LP468_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2082107.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1012..3261
                     /locus_tag="LP468_002640"
     CDS             1012..3261
                     /locus_tag="LP468_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2082108.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3264..>4418
                     /locus_tag="LP468_002641"
     CDS             3264..>4418
                     /locus_tag="LP468_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2082109.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1557 a          625 c          806 g         1430 t
ORIGIN      
        1 atgtaataat ataaacataa taaaacaaaa attatccaaa tctaacatag gagggtggat
       61 atggaaaatt ctatatattt agtaacagaa cctaacactc agctgaaaga ttgttacttt
      121 aatttttgtg ggtattcaaa aacagaacct agacatagtt ttggaccagc tattcgagaa
      181 caatacttaa tacacatagt gctagaaggt gaaggctatt attcaattaa tgatcaaaaa
      241 tattttctga agaaaggcca aggatttgtt atcccaccag gagtatctac tttttatcaa
      301 gcagatgaaa aaaatccgtg gtcatatgta tggttgggtt taagtggcaa tcttgtagaa
      361 tactatctaa aagaaattgg tgttggaaag aatcatctta cctttaaagt cgaaaattta
      421 aattcattta aaggattaat ttttgaaact ttatcgtatg atcaggacaa tctagtcagt
      481 gaattgtcca gacaaaaaca agtttataaa tttttagaac tcctcttaaa ttcagctagt
      541 tatctgaacg aagggataat tactaaaaag atgaatcctt ttgttcgtca aacaattgaa
      601 ataatacgtg agaatgcgta tcaaaaatta tctgttaaag atattgctgt cagtctatcg
      661 atacacgaaa attatttatc acgattgttt aagaatgata tgggaatatc aataaaagag
      721 tatattagtg aaatcaaaat ttctattgca aacgatctgt tatcatcaac tgaatattca
      781 atccagcaaa tcagtgacaa gataggattc tcaacagtac aatctttttc taaagccttt
      841 aagaaagcaa atggtgtttc accgggagta tatcgaaaac gtagattagg tctaggaatc
      901 attaatggtg aataaactaa acatttgatt ttgataaata ttcgttactt taaacgctta
      961 ctatttatgt gagcgttttt tataatgcaa taaagaaacg gaggagagct tatgtataag
     1021 gataatgaaa tgaatattat ttatcgatca gaaaaccaac aatttcattt gtttaatcag
     1081 gagataagtt acatttttaa gatatcggaa gatggtaaat tattgcattt atattatggt
     1141 gagaacttac cagataatga ctatagtcat ctaattgaga tgcatcatcg gcctatgaca
     1201 acctatagaa atgaaaacga tttgctatat tcgttagagc acttaaaaca agaatttcct
     1261 gaatatggta caacagattt tagacatcct gctatttcat tactacagaa aaatggctct
     1321 cgcttatcag attttgtcta tcaagggtac gaagtggaag aaggaaaacc taaactagaa
     1381 ggtttacctg ctacctatgt tgataataat gatgaaagca aaacattgaa agtttatatt
     1441 ttagattcag ttacaaatgt tcaagtagaa ttattatata caatttatag agattatcct
     1501 gttattactc gtagcgcgcg agttatgaat aaaggaaaag atattcaaat aatcgagaat
     1561 attagcagtt tatcattgga tttacccgat gcaaattatg aatggcaaca attatctggt
     1621 gcttggggta gagaaagaac tattaagtcg cgtactttac aacaaggaat tcaatcaatc
     1681 gaatctactc gaggtatttc aagccatcag cataacccat ttgttacttt aaaaagaaaa
     1741 aatactgatg aaaatcaagg agaagctatt ggtgcagcac tagtttactc aggaaacttc
     1801 ttaattcaag cagaagtaga tacatgggat gttactagac tacaagttgg catcaatcca
     1861 tttggattta attggaaact caatccagga gaaatattta cagcaccaga agcgattctg
     1921 gtttattcaa gtaagggttt aaatgccatg agtcaaactt ttcatcaact atttagaaaa
     1981 cgcttagctc gtggtaagtg gcgagaaaaa gaccgtcctg tcttaattaa taattgggaa
     2041 gcaacatatt ttgattttga cgaagaaaag ttggtaaata ttgctaaaaa agcatttgat
     2101 gttggtattg aattatttgt attagatgat ggctggtttg gagaaagaga aaacgattgt
     2161 gcaggattag gagattggca tgtaaatcct aaaagactac ctagaggaat cggcagcctt
     2221 tcagaaaaaa ttcgtagttt tggtatgaaa tttggtttat ggtttgaacc tgaaatggtg
     2281 aataaggata gtgagttata tcgcacacat ccgaattgga ttatttctac acctaatcga
     2341 aaacctaatc atggtaggaa ccaatatgta ttaaattttg ggttagatga ggttgttgaa
     2401 aatattttcg atcaaatgtg taaaatcatt gatgaatcaa acttagatta cattaagtgg
     2461 gatatgaatc gtccattgac tgatgtattt gacagtcact tgtcagcaga tcaacaagga
     2521 gaagtattcc acagatatgt actaggcgta tatcgcttat atgaaaaact tataacaaaa
     2581 tatcctaaca tactatttga gtcttgttca tcaggtggtg ggcgctttga tcctggaatg
     2641 cttcactatg cacctcaagc ttgggctagt gatgattcag atgcaattga aaggttaaaa
     2701 attcaatatg gaactagtat gctgtatcct ctttcgtcta ttggtgctca tgtatcaatt
     2761 gttccaaatc atcaaacaaa ccgtataaca cctataaaaa ctagaggaaa tgtagctttt
     2821 tttggtgcat ttggatatga gcttgactta aatgaattaa gtgaaggcga tttgaggatt
     2881 gtaaaagaac aaattgcctt ttataaaaaa tatagaacca taattcataa tggtactttt
     2941 tatagactat tatcaccatt cgatgatgat aatcaaaccg cgtggatggt tgttagtcat
     3001 gataagaaaa cggctattgt tgctcattat aaaacattaa atgaggtaaa tgctccttac
     3061 cgccgactga aattaaaagg gttagataat gacggacttt ataatgtagg acaaaatagt
     3121 ttgcgatctg gaatggaatt gatgagagca ggactagtct gttcagatgc atctagtgga
     3181 caaataaatg atcagaatcg acgcccagaa acatttgatt ttgattccaa gatttgggtt
     3241 ataacacagg aggaaaagta gagatgaata accaaaaaag cttacttcaa aaaggagcaa
     3301 tcttaagtat ttcactaatg ttaacaagct ctcaagcaat taatggtgtt attccacaaa
     3361 tgaaacagtc tttggggata tcacaaagtc aaagtgaact tttaggaact gcaccaagta
     3421 taactgttat tttgtttatc ttattatcta gttactttgc caaaagaata ggaatgaaaa
     3481 agacaataat tttaggttta ttattagctg gtataggagg aattattcca gtatttacag
     3541 ctaccttcca aaccgttctt attagtcgag taatattagg tgccggttta ggagtatata
     3601 attcattggc tgtgacatat atcagctctt tatactctgg caatactaga gcaacgctat
     3661 taggtattag aaattcaatg gaagctttag gtcagacaat ccttattttt cttgctggag
     3721 ttttagtgaa cattaattgg acggcttcgt ttttagtcta tgcaattgcg tttcctgtag
     3781 ctctcttatt cgcgctaaaa gttcctgaaa ttagagatga aaatagtgac atacctgaaa
     3841 atcatgtaaa agaaaagatg aatccaatgg tttttgccct agttctattt gcaatcttac
     3901 tcgtaatgaa tagtattgct atttctgtac gatttgcatc aattgcaact gaaattaaag
     3961 gggtaaactt taatgctagt aactatttag ctctaatgcc tatcttagga atactagcag
     4021 gatttatgtt tggaccaata aataagtgga taggaaaagg aaccctatac ttgggaatta
     4081 tattctttat aatttcaaat ttgttaattg ctgtgtcaaa cggtaatatg acgttcctgc
     4141 taacgggttt atttttatca agtataacag gatcatggtg cttcccattt atctttagta
     4201 acttagataa agtcactaca aagaatacaa ttaattttgc tacttcattg atttttattg
     4261 gctgtaatat tggtaatttt atagctccta ttgctatgca attagcacaa tttctaacaa
     4321 gaagtacaaa tttgactgct ccattttttg tattcgcagg aatatttatt gtgatcctat
     4381 ttgtaacatt ttttgcgaca aataaaaaaa atactaga
//
LOCUS       DAFEML010000121         4399 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFEML010000121
VERSION     DAFEML010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.126"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            117..1004
                     /gene="xerD"
                     /locus_tag="LP468_002642"
     CDS             117..1004
                     /gene="xerD"
                     /locus_tag="LP468_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL2082110.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            1023..1394
                     /locus_tag="LP468_002643"
     CDS             1023..1394
                     /locus_tag="LP468_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2082111.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            1364..2161
                     /locus_tag="LP468_002644"
     CDS             1364..2161
                     /locus_tag="LP468_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL2082112.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            2145..2714
                     /gene="scpB"
                     /locus_tag="LP468_002645"
     CDS             2145..2714
                     /gene="scpB"
                     /locus_tag="LP468_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL2082113.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            2720..3436
                     /locus_tag="LP468_002646"
     CDS             2720..3436
                     /locus_tag="LP468_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2082114.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      3518..3643
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3766..4377
                     /locus_tag="LP468_002647"
     CDS             3766..4377
                     /locus_tag="LP468_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2082115.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
BASE COUNT         1475 a          772 c          966 g         1186 t
ORIGIN      
        1 aaaagaaacc agtccgtctg agtgtctaga cggctttttc tttgctcaga ttatggaaaa
       61 agactatcag aatgaagcgg tatctgatat gatagagagg catgaggggg attattatga
      121 aagagcaaat caacgattat ctccactact tgaatattga acggggattg tccgccaata
      181 cacgacaaag ctatgaacgt gatttggaac agtacttgca ttttctacag gagcagaaaa
      241 ttgcttcatg gcaggatgtc gatcgctttt tagtcatccg ttttctggag aagttgcatg
      301 aagaaaaaaa agcgacagca actgttactc ggatgatctc aagtctcaga agattccatc
      361 agtttttacg gcaagagcgt atcactgatc atgatccgat gcaacatatc gatacgccga
      421 agaaagcaca gaaattacca agtacattga ctctgacaga agtagaaaag ctgattgaag
      481 cacctgatac gacaaaaacg ttagggataa gagatcgtgc aatcttggaa gtcatgtatg
      541 ctactgggat gcgcgtcagt gaattgattg gattgaaatt gggagatctt catctttctc
      601 ttggactggt acagacagtt ggaaaaggag ataaagagcg gatcattcct ttaggtgatt
      661 atgcgatcca atggctggaa cgctacttag acgaagcacg tccattactt gtaaaggacg
      721 catctgaaat gcatgtattt gtcaataatc atgggaaagg tctttctcgg caaggaatct
      781 ggaaaaatct gaagcagtta gtacgagagg ctgggattta caaagaagta acaccacata
      841 cgctgcggca tagctttgcc acacatctgc tagaaaatgg agctgatttg cggacagtac
      901 aggaattgtt aggtcacgcg gatatctcta cgactcagat ttatacacat atcacgaaga
      961 aaagaatgac ggatgtttat aagcagcatt ttccaagggc ttagtcatag gaaggtgaga
     1021 agatgttaac acattaccgg aaagaaaacc gtaaaattgc tatgggacta ttgagtttcc
     1081 ataagaaact gacaggtaaa acttctttgt tgaaggagat tgatacgtac gaatctgaag
     1141 acgattatga actttttttc tttacgccag aaggttcaac caacattcaa gggattattg
     1201 gtatttactg ggcaacgaac gatcagctga tcatccatga catttctttg aatccgtctt
     1261 atcgcggtga gaatatgggc tttcaaatgt tagatgaatt acaggaaaag tacccggatg
     1321 tctccatccg tgcaactgaa atcacagagc cttacattgg aaaatggcta gcaaagaaaa
     1381 agaagaaaga gtgaatgagt tgacggagat caatattaaa ttagatgtat tcgagggtcc
     1441 tctcgatctg ctgcttcatc tgattcagca aatggaaatc gatatatatg atataccgat
     1501 cgctacgatc acggagcaat atatgaatta tatccataca atgaaaacac tcgagctagc
     1561 tgttgcagga gaatacttag tgatggctgc tacattgatg gcaatcaaaa gcaagacatt
     1621 gcttcctgtc caagaattcg gcacagacga tgaagaatta tgggaagaag atcctcgaga
     1681 agaattggtc actcagcttt tagaataccg taaatataaa tatgcagctg aaagactgac
     1741 agaaaaagca gaggaacgaa gtctttatta cacaaaagaa cctatgaaca tcgatgggtt
     1801 agcggatgct gaaaagccgt tgaagcgagg acaagtcaaa aaaatcgatt tgatccgtgc
     1861 catgcagaaa atcttagaac gtaagaaatt ttctcaaaaa gtggaaaaaa cgatcacgcc
     1921 cgatgacaca acgatcgaag aacgaatggt atttatcgaa gagcgtataa aaagaaatgc
     1981 gcatggctgt actttcgatt ctttttttga gtcaccttct aaaagtgaag ttgtcactac
     2041 ttttatggct ttgctagaat tgatgaaaaa agggcagatc attgcgcaac aaaaagaaaa
     2101 ctatgaatca attatgcttt atccagcagt aggagatacc gaacatgacg aaattaagtg
     2161 aacttgaagc ccttcttttt attgttggcg aggaagggat cagtaatgaa gaattaagcg
     2221 gactgttaaa tctcagcgaa gcagaagtca caagtttagt gaaagaatta aaagaatctt
     2281 acactcaaaa ctcgcactca gctttgcata tttttgaaac ggaaagccat tatgtattaa
     2341 cgactaaaaa agagctggct cccttactta agcgatatgc gcaagggaca tcaaacacat
     2401 tatctcaagc cgccgtcgaa accttagcaa tcatcgctta taaacagcca atcacaagag
     2461 ctgaaatcga gcagattcga ggagttcagg tttcaggagc ggtacagcgt ctagctgccc
     2521 ataaactgat tgaagaaaaa ggtagagtag aaggaccagg tcggccgata ttatatggaa
     2581 caactggcta cttcttagat tattttggtt tgaaatcatt agaagaactg cctgatacac
     2641 aagaaatgga aatttcactt gaagaagacg tgtcaccaga tctattcttt gatggaatga
     2701 ataaaggaga ataattgtaa tggagagatt gcagaaagta attgcccacg ctggcatcac
     2761 ttctcgtcga aaagcagaag aattcatcct tgcaggacgt gtaaaagtaa acggacaagt
     2821 tgtaagggaa ttagggataa aagttgggaa acatgacact gtggaagtgg atgaagtccc
     2881 aatttatcaa gaagaatacg gttactattt attgtacaaa cctaaaggag ttatttctgc
     2941 tgttgcagat gacaaaggaa gaaaagttgt tacggatctt ttgccgatgg taaaagaacg
     3001 tatctatcct gtaggtcgac tggattacga tacttcgggg atcttgctac tgacaaatga
     3061 tggagatttt gctcagcgcc tgacacatcc aaaacatgaa gtggataaag tttacgttgc
     3121 aaaggtaaaa gggatcgcta caaaatcgat gcttgcacct ttgacaaaag gaataaagat
     3181 cgaaggacga aaaacatctc cagctaaatt ccaaatttta tcagtggatc ctaagacaaa
     3241 ccacagtatc gtggaattga cgatccacga aggacgtaat catcaagtga aaaatatgct
     3301 tcaagcagtt ggtcttcctg tgcaaaaact aaaacgtgaa aaatacggag atctgacttt
     3361 acaaggccta cgtcctgggg attaccgtga actgaacaaa aaagaagtca gcagtttgct
     3421 gaaccactca aaatgaacac ttacttttta taagtgttag atgttgcgtt ttttgaatag
     3481 atatgtataa tgaatatgta aacaaaaatt atataaggtt cgtcttcagg ggcagggtga
     3541 aattcccgac cggtggttat agtccacgac ctattttgca aaaaaatagc tgaatcggtg
     3601 aaattccgat accgacagta tagtctggat aaagaagata gagcttattt gacgacgctt
     3661 gatcaaataa ctctaactct attttccctg gaaaatagag ttttttcatt tggagagaaa
     3721 cgtcaaaaag ttcgctgaag aggagtccta acaggaggat ttcaaatgaa gaacacccgt
     3781 gtacagaaaa tggttgcagt agcgatgttt gctgcgatcg cattagtttt acagtatttt
     3841 gcttttccga tcatgccggc ttttagtttt ttgaagatcg attttagtga tatctcggta
     3901 ttgatcagca tgttcttatt cggtccagcg gccggagttg caacagcgtt cttgcgttca
     3961 gtattacatc tgctgactac aggtttttct ccggataatt tggtaggaga cactgctagt
     4021 ttcttatcaa caacgatctt tacattcccg atttattatt tctttagtgt aaagaaacag
     4081 cataaaggaa gaaacaaatt tttaggtgtc attacaggaa ccatcgctct aactattttt
     4141 atgagtatcg caaattattt cgttattacg cctctttact taatgttttt agggctgaac
     4201 gcaacacaga tgctgggcat gtctttagca aactatgtac tgattgggat cgttcctttc
     4261 aacttgatca aaggattcat cgtgagtgct gtctttttag tgctgcatgc gcaacttctt
     4321 ccatggttaa gtcgaaaaca acatcagttc gaacaacgtc atacagcagt caaataaata
     4381 tcaaaaagat caagaaatt
//
LOCUS       DAFEML010000122         4379 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFEML010000122
VERSION     DAFEML010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.127"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(1..348)
                     /locus_tag="LP468_002648"
                     /pseudo
     CDS             complement(1..348)
                     /locus_tag="LP468_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            418..579
                     /locus_tag="LP468_002649"
     CDS             418..579
                     /locus_tag="LP468_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL2082116.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            598..1875
                     /locus_tag="LP468_002650"
     CDS             598..1875
                     /locus_tag="LP468_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2082117.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1885..2541
                     /locus_tag="LP468_002651"
     CDS             1885..2541
                     /locus_tag="LP468_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2082118.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2541..3917
                     /locus_tag="LP468_002652"
     CDS             2541..3917
                     /locus_tag="LP468_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2082119.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            4047..>4379
                     /locus_tag="LP468_002653"
     CDS             4047..>4379
                     /locus_tag="LP468_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2082120.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1688 a          502 c          773 g         1416 t
ORIGIN      
        1 aaatatttag aattttgcac atcgctgata tggaatattt atgcttgttg gcatcaatta
       61 cttgtctttt cgtccgaata tcagcgccgc ttgctttaaa atatcattct ccatttcgag
      121 ttgcttattt ttctttctta gtgcgatcaa ttctgcttgt tctggtgtta agttgtctct
      181 ttctttgaat gagcccgttg attgtgcttg cttcatccat ttatcgaaag aagaaggcgt
      241 aagctcatac tctcgaataa tttctgcgcg aggcttacca gcgagataga gatcgacgat
      301 ttgttgtttg aattcttttg aataggttct tcgttgacgt cttggcatga aaaatcctcc
      361 agtgtgtttt ttattattct acacacctta ttttttctgt ctagtctagt gtagccgatt
      421 caggataagg ataagtgtat taattgtgga aaatgtaaaa aagtttgcca aatgaataaa
      481 gattcagttg agaattgcaa tcatctggag tgtatcagat gtggacgatg taaaaatgct
      541 tgtccagtgg atgcaattag ttatggagta agaaaataga gaggagtagt taggaaagtg
      601 ataaaaaatg ctatagcata tattacaaga aagaaaaata gaactttaat aatttttatc
      661 atattaacta tagttctttc ttgcttgtat tcttgtttaa caataatgaa atcaagcaat
      721 gaaatagaaa aggctttata tgaaagttct aattcttcaa tatcaataac aaaaaaagat
      781 ggtaaatatt ttaatgttaa tcaatttaaa gatattgaaa aattaaaaga aattgaagaa
      841 aaaataattc aatatgatgg attagcaaaa ttaaaagatg ctaaagtagt tagcggagaa
      901 caaagaataa atagagaaga tttatctgac gaatttaaga atgttgtttc actcgaagct
      961 acaaataata ctaaaagaaa tattttattt agtagtggag tatttacaat taaagaaggt
     1021 aaaaatatag aagaaaatga taagaattca attattgttc atgaagaatt tgctaaacaa
     1081 aacaatctaa aattaggtga tgaagttgat cttgaattac tagatattga aaaaagtgga
     1141 aaaataaaaa gtcataaatt taaaattata gggatctttt ctggtaaaaa acaggaaaca
     1201 tatacaggat tatcttctga ttttagtgaa aatatggtgt ttgtagatta ttcaacaagc
     1261 caagagatat taaataattc agaaaataat gaaattgcaa ataaaatttt aatgtattct
     1321 ggtagtgcag aatctacaga cttagcctta aacaaattga aagagcttaa aattgatgag
     1381 tcaaagtatt ttgttgaaaa agattctaat gcgtttgaag agtctttaga gtcagtgagt
     1441 ggaataaaat atataataaa agtaatgact tattctatta tgttaggtgg gatggttgtt
     1501 ctttcattaa tcttgattct atggttaagg gaaagaattt atgaaatagg tatattctta
     1561 tctattggaa catctaagat acaaattata atgcaattta tattcgagtt aatattcata
     1621 tcgataccaa gtataatatc ttccttattt ttaggaaatg tattactaaa agtaattgta
     1681 gatggattca ttaactcaga ggattcaatg atttccggtg gaagtttaat aaataatagt
     1741 agttttatgt caaatataac aacacttgga caaagttatt taatattaat aagtattatt
     1801 gttttatcag ttgtatttgc ttcttcatta atgttaatca agaagcctaa agaaatctta
     1861 tcaaaaataa gttaggagaa aataatggat atattagaaa taaagaatgt agcatatagt
     1921 tatgcaaatt ctaaagaaaa agttttgtca ggagtaaatc aaaaatttga acttgggaag
     1981 ttttatgcga tagtaggaaa gtcaggaaca ggaaaatcta cacttctttc cttacttgct
     2041 ggacttgata aacctcaaac aggaaaaata ttgtttaaga atgaagatat acaaaataaa
     2101 ggatatagta atcatagaaa aaataatata tctttagtat ttcaaaacta taatttaata
     2161 gattatttat caccaattga aaatattaga ttagtaaata aatcagcaga tgaaagtatc
     2221 ttgtttgaac taggtttaga taaaaaacaa ataaaaagaa atgttatgaa attatctggt
     2281 ggacagcaac aaagagtagc tattgctaga gcattggtat cagatgctcc aataatacta
     2341 gctgatgagc ctactggtaa tctagacagt gttactgctg gagaaataat taatatatta
     2401 aagacattag ctaaagatag aaataaatgt gtaatagttg taacacatag taaggaagta
     2461 gcagattctg cggatatcat tttagaacta agtggtaaaa agttgaaaaa agtaaataaa
     2521 atgaatttgg aggttgaata atgataaaaa atgcatttgc ttatgtaact agaaaaagtt
     2581 taaaatcatt aattatcata ttagttattt tatctatgtc aactttaagt ctcattagtt
     2641 tatctattaa agatgctacg gacagagctt caaaagaaac atttgctaat ataacaaata
     2701 gtttttctat ggagataaat agacaagtaa atccaggaac acctagaggt gggggaaatg
     2761 taaaaggtga agatattaaa aagatatctc aaacagatag tatagactcc tatgtaaaaa
     2821 gaataaacag tgttgcagat ttagttgatt atgatattat tgaaactcaa gagactcttg
     2881 cgaatcaatc acctgaaaga gcaaagaatt ttaaaagaac agttatgtta actggggtta
     2941 acgactcaac aaaagaaaca aaatttgtat cagaagcata taaattagta gaaggaaagc
     3001 atttagaaaa tgaagataaa aataaaatct taatgcataa agatttagct gaaaaaaata
     3061 accttaaagt tggagataag ataaaaataa aatctaattt atttgatgct gataatgaga
     3121 aaggtgcaga tgaaacagta gaagtagaaa ttaaaggtct attcgatggg cataatagcg
     3181 gtgtagtaag tgcagcacaa gaactatacg aaaatacatt aatcactgat attcatacag
     3241 ctgctaaagt ttatggtaat accgaagata cagctgtata ccaagatgca acattctttg
     3301 taaaaggtga taagaatctt gatagtgtaa taaaagatct tgggaaatta gatataaatt
     3361 ggagagaata taatttgatt aaaagttcat caaattaccc tgcattacaa caatctatat
     3421 caggtattta ctcaatttca aataaattat tttttggctc attaatattt gcaggagttg
     3481 tagtttcatt attattattc ttatggatga atgctagaaa gaaagaaata gcagtattac
     3541 tatcattagg tatatcaaaa ttagaaattt ttggtcaatt cctaattgag atggtattta
     3601 tatcaatccc cgcattcgtt ggttcctatt tcttagctca atatacagct gacaagcttg
     3661 ggaataatat attgaataag gttactggtg atatagctaa acaaatagct aaacaatctg
     3721 catctagcca attaggtggt ggggcagaag ctgaaggatt taacaagaca ttatcaagtt
     3781 tagatatcaa tgtattacct aaattcatga tttatgtagt tatatttatg agtttagtac
     3841 ttcttgtatc attgattatt tcttcattca atatattaag aaggaatcca aaagaattat
     3901 taattgacaa taattaaaat tttcggtgct ttttagcacc aaaaatgaga gtgtaatata
     3961 aaccgtgtaa gtaaccatca atcctaggcg ggtggttgct tcacggtttt tatttttcta
     4021 aaataagatc aagaggtgat tacacgatgg ctagaaagaa aagaaatcct gatgctgaga
     4081 agttagctga atccattttg aatacttatc aacccgaatc tgtagaggat atgcaagatg
     4141 ttttaaaaga tgtgtttggt cccttatttg aaaaaatgct tcaaggagaa ttgaataacc
     4201 atttagggta tgacgcccat tctaaagagc caaagaaaca tgacaatcga cgaaacggtt
     4261 atggcaataa gacgcttaaa acgagctttg gtaaagtaaa cattgatgtt cccagagacc
     4321 gggaggcttc ttttgaacct gagttgattc ctaatagaaa acgagatgtc tccgacatc
//
LOCUS       DAFEML010000123         4257 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFEML010000123
VERSION     DAFEML010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.128"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(179..682)
                     /locus_tag="LP468_002654"
     CDS             complement(179..682)
                     /locus_tag="LP468_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2082121.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(805..1569)
                     /locus_tag="LP468_002655"
     CDS             complement(805..1569)
                     /locus_tag="LP468_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL2082122.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1677..1952
                     /locus_tag="LP468_002656"
     CDS             1677..1952
                     /locus_tag="LP468_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL2082123.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            2390..3340
                     /gene="yidC"
                     /locus_tag="LP468_002657"
     CDS             2390..3340
                     /gene="yidC"
                     /locus_tag="LP468_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2082124.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(3519..3719)
                     /locus_tag="LP468_002658"
     CDS             complement(3519..3719)
                     /locus_tag="LP468_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082125.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
BASE COUNT         1262 a          906 c          760 g         1329 t
ORIGIN      
        1 acaaaagtcg tgtcaaagtc ccttgtttcg aatgaatggt gttcaaaagc tggcatctgc
       61 ggtaataagc cgaaacttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
      121 tcttgaagct gaccacttct gtcacaacct caatatggtc tattattggt tttatctatt
      181 aaatcgagga ttctttccca aagtaacgtt gccatctctt acgcatactt gctgacatag
      241 gctgagcggc ttctttgact gcgcagtatt tgtctacgaa tgttacgata tatccttctt
      301 tgtacttagg cggtgcaatc gttgcgcccc acatgtgctt caaaatgata tctcgctcaa
      361 gatccgacaa ttcggtgatc ttttctgcat tctttacagc aattcttgga tggatatacg
      421 catgtgtgcc ttcatcaaat ttcgtcgtac gccaatcata gtagaacaga tcatgcaaaa
      481 gtccagcacg cgctgttgct ttagcattgc caccccattt ttttgcgagc agataactat
      541 agtaagaaac actgatggaa tgctccaaac gagtggaatg aacatgctgt gtgtaattcg
      601 ctaatttttt cactgcttct gtttctaaaa gatcttctac ataagacata tattcttcgt
      661 cttcacgcca tttttctgtc ataattatcg atctgccacc tttttgaatt tcattttctt
      721 ctgaaattga tctaagtata ccaccagtgt tcggattatt ctagtcgcct tggataaaat
      781 agccaaagct taatagttcc ttaatcataa agaaaaatga taaagaacaa tccctgccgc
      841 aaccccaaca ttcaacgatt ccgcatttcc tttcatcggg atatatacgt tctgatcagt
      901 caaagacaag atttcctgac ttaccccctg accttcgttc cccatgatta ttgcgaagtt
      961 atctgatttt tctactttgt ctaatgcgtg tgcttcttca tttaattctg tgccatacac
     1021 tgtaaaccct ttgtctttca ttaaaggaat cacttctgtc aaatcttttt gcaacacagg
     1081 caaatgataa ttgcttccct gcatgctgcg cagcaccttt gtactataaa tatctgccgt
     1141 tcctttgcct aataaaacac cagccatatc aaatgcatct gccgtacgga tcatcgtccc
     1201 tacatttcca ggatcttgta cattatctaa caacagccat cctcctgaaa aatctggcgt
     1261 gccttcagcc gttaacgcca tcactgctaa gattccttgt ggtgtaggta gatccgatac
     1321 agcatccatg acctcatccg aaactagaaa agtagaaatc tctttgtttg cggccagcca
     1381 gtctccccat tctttcatgc ctcgctgtgt cacaaaaagt tcttttattt ctgcatcaga
     1441 cgacgcagct tcttcaatca gatggaaccc ttccaaaaga tattcttcct tttcttcccg
     1501 atatttcttt ttatgtagtt tttttaattc tttgattctt ggattttttg ctgattggat
     1561 ctctttcaca ttcctcacct ccccatgatt atatcatgga ataggtgctt gagcttgttt
     1621 catcctaaaa aaatcggtat cattaattta taaaatagga aagaaaggtg acgaacatgc
     1681 gcaaagttaa aatgaacgtc caaggacgcg tccaaggcgt aggatttcgc tacatgacca
     1741 agatggtcgc tgatcaacta ggcgtgactg gaacggtaaa aaacgaagat gacggctcag
     1801 tcacgatcga agcaatcggc aatgacgaca tcatccagaa atttattgaa gaagtcaaga
     1861 aatctccgag cccaagtgga cgagtgcagt atgtggatgt ccaagaagac ccgatgattg
     1921 aggaacgaaa gaaatttgat gtggtgggat aaggttgtga aaaagctggt ctgcatcaag
     1981 cattaaggac aggttgtgaa aaatagctct ccatattttt caacaggctg gacttaatgc
     2041 cgtagatgca agcttttgaa caccgtcgat aaggttattc ttgaggcgct ttgcctcaaa
     2101 aattaaggac agcagtgaaa aagctgatct atcacttgca gtgagttcat ttgactccgc
     2161 tttttcgggc agaaaaaaag tttttagttt attaaagtaa gaaagaaaca cttggaatca
     2221 ttctactttt tcctagtatt tctttcttga ttttttgtct ttttttcaaa atttttcgct
     2281 acgtaaaaga acgaatattt atatgaaatt tctatgaagt tgattgaatt ccatgcgctt
     2341 ttttagtata gttaagtttg tgtaaaaatt atagaagagg aagtattcta tgaataaatg
     2401 gaaaaactgg ttattgggat ccggacttgt cagtatcctg ctctttttat ctggctgtgt
     2461 gcggatggat tcaaacggaa accctgacac ttcgggaatc gtttatcgag tactcgtcca
     2521 tcctatgggc caagcgatta catatctagt tgaaaatttc aattggtctt atggctgggc
     2581 agttattgca atgactgtga tcgtccgtat catcatcttg ccactaggta ttagtcaatc
     2641 gaaaaaaaca atgatccaat ctgaaaaaat gcaagcgtta aaaccacaag ttgaagcagc
     2701 ccaacaaaaa ttgaaagctg caacaacacg tgaagaacaa atggcagcac aagcagaaat
     2761 gcagcaagta taccgcgaaa acggattgag tatgaccggc ggaatcggct gtctgcctct
     2821 attgatccaa atgccgatct tctctgcctt gtactttacg gcacgttata cagaaggtat
     2881 ccgggaatca tctttctacg gcatcgattt aggctcacca agtatggtac ttgttgccat
     2941 tgcaggggtc gcttatctgc ttcaaggata catctcaacg atcggtattc ctgaagaaca
     3001 gaaaaagacg atgcgtacga tgctgatcgt ctctcctgct atgatcgtct tcatgtcgat
     3061 cagtgcgcca gccggtgtta cactttactg ggtagtcggt ggtgtgttca gctgtctgca
     3121 aacattcatc acaaacgtta tgatgaaacc acgtttgaaa gcacaagtgg cagaagagtt
     3181 gaaacaaaac ccaccaaaac aagtcgtcac tccaagaatt gatgtgacag aatcagctaa
     3241 accagctgac agcaaacaag caaccaaaca aatcaagcaa cccaaaaaca gtacaaacaa
     3301 taaaggccgc aacgcaggaa agcagcagaa gcggaagtag atagtaaata agagtgtaat
     3361 aaaaattcat taacagtttt agcaattaaa aatatcgacc aagatttttg aaaaagaaat
     3421 ctggtcgata tttttattta agtgaatgtt taatttgaat catcgattga tcgctatcta
     3481 attgcagcag catcttttta tgaagaaaca actttttctt atctatcaac gtagacaggt
     3541 gttgctgttt cttctaatag tgtacttaat tccttaatat tttgttttcc ttcttctaac
     3601 atccaactac tcgctttttc ttcgccttcg gtaacaaaag gcgccactcc cttcgcccat
     3661 gttgctcgcc cacataagac accattctcc ataaaggaca acgcggagat accacccatc
     3721 taaataacat ccataaacct ttctagtaga agaatagtga tagtatccat ccctttttct
     3781 actgggaata caattacacg attcaaagct tgatacacaa catttccctt cttataaacc
     3841 gctattgtaa ccgaattgtt ttgaatcacc tttttgggat agaaactggc tcctttccgc
     3901 aacttcttaa atgttggttt cttttatact ttctttgtag caactacaaa tttcttcaaa
     3961 tctctaaatg tttgcataac aaccgccttt ctgactttta ctcaggatgg tatttaaaaa
     4021 tcagcaaaat aaggcttctc tccatctttt ttatttccta gctgctttaa agacactctt
     4081 gctgtttttt aatctctatc aagggggctc tgaatctatt ttgatgaact tatcttatta
     4141 atttctcaaa tgagctgtca gacacaactg tattttttca atctcatacc ggacaactat
     4201 gccagcttaa aaaaatttcc tctggcaaaa cttctttatt gaaaaatgac aatgaaa
//
LOCUS       DAFEML010000124         4153 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFEML010000124
VERSION     DAFEML010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.129"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..106
                     /locus_tag="LP468_002659"
     CDS             <1..106
                     /locus_tag="LP468_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2082126.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(359..508)
                     /locus_tag="LP468_002660"
     CDS             complement(359..508)
                     /locus_tag="LP468_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082127.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            970..1182
                     /locus_tag="LP468_002661"
     CDS             970..1182
                     /locus_tag="LP468_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082128.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1460..3259)
                     /locus_tag="LP468_002662"
     CDS             complement(1460..3259)
                     /locus_tag="LP468_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2082129.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3383..3979)
                     /locus_tag="LP468_002663"
     CDS             complement(3383..3979)
                     /locus_tag="LP468_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2082130.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1490 a          728 c          707 g         1228 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaaaac gcatatacct gcggtggcag gttatgcgtt ttttgttgta taaagacttt
     1441 tttcattaac gatttttgat tagccgactc ccaaaacaaa atttagcagt ttatctgaat
     1501 aagtgatttc ttcatctgtt tgtttcacac tttcatttag tagtcccatc tcatcggtta
     1561 tgataccatc cacaccataa aacatcatgc gactcatagc atctgaatcg ttgattgtcc
     1621 atacatatac ttcttttccg tcttggtggg cagaattaat gaagttacgg ttgatcgtac
     1681 tatattccat tgtcagaaaa tcagcaggcg tcacaggggg cccaacaata ttgaaaggta
     1741 agatgtagcc cacataaaag tttggttctg cttcttttaa atctgaaacg gtttggtacg
     1801 tcaaactttg caaaatatga tggttctcta agataacttt gcggtattta tggacaaatc
     1861 gttcgacaag gtcatccgaa tcttttttag aggtcttgat ctcaataagt aatttttggt
     1921 ttagcttatg tgctttttcc aaataagaat caaaagaaca aacaggggct tgcactccgt
     1981 tttcagtaac tgtaagattt gtcaattctt tcaatgtaag atcctgtggt gttccattta
     2041 cccctgttaa gtgacgaaga tttgcatcat gcatcactac gaaatgacca tcttttgttt
     2101 cctgaacatc catctctaca taatcaggat gatagtctct gcttgttttt tcaagtgctt
     2161 ctaaagtatt ttgcgcccca ttttgggtac tcacacctct gtgagagaca gtcactggtt
     2221 ttgtctgaac agctgaagtc agataatcca tattgtaaag acagacgcca ataccgaaaa
     2281 aaactgcaaa aagagtcaaa ccagtgtttt tcagcgcaga gaaacgcaag ttgggggctt
     2341 gtgggataaa ccacttaggg atctcaggca agaagccttc gtcatccatg aaatcaacaa
     2401 tgatataaaa aatccctacg gtagacatca cgatattgaa taataaaatc ccttgtaaaa
     2461 gcgtcatagc aaacacagcg ctgatcaatg catagtctgg gaaaaattgt tcaaccatac
     2521 tttgtgccaa aataacaacg atatatccta aagaagaaag gagtaaaatc gtaccgccaa
     2581 tcacaataaa ttggcccgtg atggccaaaa gacgcgattt ggtcaatgac cagctttccc
     2641 gaatggctgc tcgaaaagga cgatctcgta gaatcatttc cggtaaagca aaaatcagtc
     2701 gaatcccaat atagccaagg aaaatataaa cgagtaaaaa ggaactgacg atgatccaac
     2761 gattagcaaa aataaaatcc ataatgaaag cggggatttt tatttttgac agtagatcag
     2821 aattaaaact taatccgctg atcggtagaa tcaataaaaa ataagcaagg aaaaacaaaa
     2881 aagtaatggg tctcactttc ttcagctgaa gtatcgtcaa gtgtaagagt tgcttcaaag
     2941 agattggttc tttcttttta ataaaaaaaa cactcatcaa aagaaaagta aattcgaaat
     3001 aaactaacag taaaatcgtc atcaaaacta cgattaacga gagtagaacc ccaggatgtt
     3061 gagaaaaaat tgaaggaata ttgtcataag acaaatagtc aattgcccct cggtgtaaaa
     3121 taaaacgggt cgtactgctc aataagggta aacaaataaa taaaataaag ccatgcatca
     3181 gcaagacatc acggaaataa gcttgtgttc cttttaaaaa gtcccaagca ttacctaagc
     3241 tacgtttcaa ataattcatc ctatcacctg ctcttcacat tgtagcgcaa atctaatgaa
     3301 aaaggaaagg gtgcagtgtg ttttgcagac cctttcccag atttaacatt gtcaatcaat
     3361 gactaatttt acaaaataaa tattatccaa gaagaccact tagatattga cctccataaa
     3421 tcaaggccat actatataag aaaatcgaca gtggtttagc aatcaaaatg attagtgtat
     3481 atcgtttcac tgacatgttt gtcaatccag ccatcaaaca taacgcatcg tcaggagcaa
     3541 ctggaagaaa aatagctaga gcaaacagct tctcaaaacg gttttgatta tccagccagc
     3601 caatatattt gttatatgtc ttatcgctaa tcatggaaag tatgaatggc tttccataac
     3661 gacgccctag cagaaaaatg ataatcgaac caatgcagat tccaatatag ttatagataa
     3721 atccagcata agggccaaat atcaggacac cagctgcagt actgatccct ccaggaatga
     3781 ttggaataac tacttgcagg atttggatga agacaaaaat aatcggtcct aaaatgatgg
     3841 aatcacctac taatcctctt aacgcattca aatctttgaa aacacctaaa ttaataaaat
     3901 aaatcgtcag cgcgattgat aggcctaatc cgataatgga tatgaaattt atcagttttc
     3961 gagaggcagc aatattcatt attcatcaac tccttagagg ttctttgtta actatacttt
     4021 actagaaaag caactaactg cgccattttt tgatatgaca gaaaacaaac aattttgtaa
     4081 gttcatcata agtataaaag attgatctca aaaaaacatc caactaaaga cttatttaat
     4141 aacttgtttt ttt
//
LOCUS       DAFEML010000125         4120 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFEML010000125
VERSION     DAFEML010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.130"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(45..1022)
                     /locus_tag="LP468_002664"
     CDS             complement(45..1022)
                     /locus_tag="LP468_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL2082131.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="LP468_002665"
     CDS             complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="LP468_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL2082132.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            complement(2595..4019)
                     /locus_tag="LP468_002666"
     CDS             complement(2595..4019)
                     /locus_tag="LP468_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2082133.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT         1132 a          874 c          722 g         1392 t
ORIGIN      
        1 aatttaaatt gataagccat gactttgttt cgtcccttct tttcttaaaa ttccgcgatt
       61 tcttttactt tgtcttcgat atcttttgca tttggcaacc agacattttc tgcttgtcca
      121 aatgggaaga ctgtatcagg tgcagaaact cgtccgattg gggcttctaa tgaaaggata
      181 gcgcgttctg agatctcaga aactacttgc gcggcaacgc ccgcttgtcg ttgtgcttct
      241 tggacaacaa ctacgcgacc agttttttcc acggattgaa tgatcgtttc tacatctaat
      301 ggcgcaactg tacgaagatc aatgatttca acagatatat tttcttttgc aagattgtct
      361 gctgctttga ttgcttcacg caccattgct ccgtatgtga taatagatac atctgttccc
      421 tcacgagtaa ctgctgcttt atccaaagga acttcgtaag cttcatccgg cacttcttct
      481 cggaatgagc gatatagttt catgtgttct aggaaaacaa ccggatcgtt acttctaata
      541 gaagaaatca atagtccttt tgcatcataa gggttggaag gaatcactac tcgaatacca
      601 ggagactgag cgatcaaacc ttctaaatta tccgaatgca attctggtgt atgaacaccg
      661 ccaccaaatg gcgaacgaat tgtgatgggt agatttctag tgccgctcat tcgatatctt
      721 gtacgagcca tttgagctac tacttcgtcc attgcttcga aaataaaacc aaagaattgg
      781 atttcaggaa ctggacgaaa tccttctaac gcaagaccga aactcaatcc tgcgattcca
      841 gattcagcta aaggagtatc gaatactcgg tcttctccga acttttcctg caatccttca
      901 gttgcccgga aaactcctcc gtttttccca acatcttcac caaaaacaac gacattctcg
      961 tcattttcta gttcaagtgc taaggcatct gtgattgctt ggatcattgt tttttgtgcc
     1021 atgattattt cgactccttc gcttcataaa ttgcaatttg ttctttgatt gattgtggag
     1081 atacttcgaa catgtttttc aagaaatctg aaaccttttg ttttggtact ttgtcggctt
     1141 cagcaatagc tgctttgatt tcttctttag ttgcttcgat gacttgttct tctttttctt
     1201 cagaccaaag tcctttttcc gtcaaatatt tacggaagcg gatcaatgga tcttttttct
     1261 gccaatcgtc atctgtgtct tttgtacggt agcgggttgg atcgtcacca gatagtgtat
     1321 gtggtccata acgataagtc agtgtttcga ttaggactgg tccatttcca ctgatcgccc
     1381 attcccgtgc cattttagat acagtatata ctgcaagcgg atccattcca tcgacttgaa
     1441 taccaggaat cccagctgcg acagcttttt gtgcaagtgt ttttgctgca gtttgttttt
     1501 cacgaggtgt agagatcgca tacccgttgt tttggatata aaatacggca tttgcatggt
     1561 aagcgccagc gaaattgatt gcttcgtaaa aatcaccttg tgatgaaccg ccatcaccag
     1621 tataagtgaa gacgacattt ttcttgtttc gtttcttcaa acctaatgca acaccggctg
     1681 cttgtacata ttgtgcaccg atgataattt gtggtggtag agctttcaat tcttccggat
     1741 aagaattacc tgcagcatgt cctcgagacc ataaaaaagc ttgagataaa ggtaaaccat
     1801 gttttactag ttgaggtaca tcccgataac ctggaagaag aacatcttct ttatcaaatg
     1861 cgtaagcact agccagctga cttgcctctt gtccagcagt tggtgcaaaa aagcctaggc
     1921 gtccttggcg gttcagcgct gttgaacgtt ggtctaatac acgagaccat accatatgag
     1981 tcattaattc aacgagttca tcatcggata aatcaggtac taaatctttg ttaactacgt
     2041 ttccatcttg atcaagtgct tgatatactg ggaaatctgc attgacttca tctagcagtg
     2101 cttggaagtc gatcggtgct tttttgtttg ccatttgtca cacattcctc tctcatctat
     2161 aagaaaatct cttcattctg cgattgaaac agtgaataaa actgtatcac tatttaaccg
     2221 tcttcattaa taaattatca tggatttatg agaaatacaa gctaaaagca caaattttca
     2281 cgatgaaagg aaattatgcc aatccgcata ttaacagcat tagtgaataa aatcacaata
     2341 aggaaagcgt tttatatttc atctgcattt tttctatttt ctaatcaaac ttacaaccat
     2401 ctgtttctat ttaaaaacgt tggtgttata cagttttgtt gcaaacattt attttattta
     2461 cacatcgtga acggacgtac aaataatggt tttttcttag tttctttata tcgtattctt
     2521 tttccgaaaa aaaagaaaca gcttgaaatt taaatccaag ctgttatatt ctttaatcta
     2581 tttactttgt gaaattattc tgttaaccac ttttctagaa ttttcatctt tgaataaaac
     2641 aacggtattt ggttttcatc cagcctactg taattgattc tgattccatt tatatcttgc
     2701 ccaaaaagta gacttggtgc aattccaaga cccatatcta ctactttttc tgctagttcg
     2761 gggtctagtt ttttcccatc ccaagtaatc caggcatagt aaccacctaa aattgaatga
     2821 agcttgaaaa acgattgtga atctccccaa gcgcttatca gtcggctttt ttctttcaac
     2881 ttttttctta catcttgcat tttcaaatca attgcttcat taaatacatt agccactgtg
     2941 atttgtgtaa ggatattcat cgaaaactcc atcatttctt gcgcttgagc tagttgcgag
     3001 ataaaagtct caggtcctat cacccaaccg attttcgttg tttttcctaa aaccctagat
     3061 aacgaaccga cgtataacac attatccgga tcaatcgttc gtataggaag gacttcttct
     3121 tggtttagaa atgaaagatc cgtaaataca tcgtcttcaa taattggaag ccgatactgt
     3181 cgacacaatt ctactagctt ttctcgtcgt ttttgactca tcacttttcc tgtagggttt
     3241 tgaaaattcg ggttgataag cactgctttc aatttatttt tatggatcga ttctttcagt
     3301 ttttctaagt cgatcccttc ttcatccatc ggtatcccaa ataaacgcgt tcctgaagct
     3361 ttgaaaagag gtaatcggta aaaaaaagaa ggtgactcta cagctatccc ctctccagct
     3421 gaaagaatcg tttgtaaaat caaaaagatt gcttgctgac cgccaccagt cacaagaagc
     3481 tggttggggg aaaatgccaa ttcaaattta ctttccaaat accgtttgat tttgttacgt
     3541 aacggagtat agcctaaaag atccatttct ttttcttccg ctaagatttc ttcaagagaa
     3601 taagaaggaa actcaaaatt cggcaaaagc tcatctggca tctcgctagc gtataaatca
     3661 agaaacgatg ttttttggat ctgctttgct tctcttattt tttgctcata ccagtccgtc
     3721 tgctcataac gaggagagat catttgccgc caatcgattc ttggaacagc gaatttcccc
     3781 cattcagtct gattaacaaa ccatccgctg ccacgtttgc tcgttagtac cccaagctcc
     3841 ctaagctctt ccaatgcatg gacaacggtg gaacgattca caccaaaaag ttgccctagt
     3901 tttcgttctg attcaagttg acttccagga ttgatccttc cgttttcgat ttctctcata
     3961 atctgttcca taatttgacg ataaatcggt ccttgttttt tctctacttt ttcccacata
     4021 agcttctctt ttctattgtc tattttttct tttgatttta ccgaatttac gagaaaaaag
     4081 aaaaactttt tttgcaaaac ataagggact gtgacaaaaa
//
LOCUS       DAFEML010000126         3806 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFEML010000126
VERSION     DAFEML010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.132"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..321)
                     /locus_tag="LP468_002667"
     CDS             complement(<1..321)
                     /locus_tag="LP468_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2082134.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSART"
     gene            1063..1380
                     /locus_tag="LP468_002668"
     CDS             1063..1380
                     /locus_tag="LP468_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2082135.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1471..1836)
                     /locus_tag="LP468_002669"
     CDS             complement(1471..1836)
                     /locus_tag="LP468_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082136.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            2044..2526
                     /locus_tag="LP468_002670"
     CDS             2044..2526
                     /locus_tag="LP468_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082137.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2723..3613
                     /locus_tag="LP468_002671"
     CDS             2723..3613
                     /locus_tag="LP468_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL2082138.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1289 a          594 c          697 g         1226 t
ORIGIN      
        1 ggtacgagca gaacaactaa taggaaacgc tgcacgacca acaatcacat cgggtgtcca
       61 tccttgaaca acctttcttt gaatatattc tgattgttcc tcgggtaaaa caagcggacg
      121 tctaccacag tttgatttgt ttttcttata ctgttgataa tattctaagg ctgattttcc
      181 ttgcttgaag aacagatata ctttatggat cgtttgtctt gaacgattca agcaatgggc
      241 agttttagca acagattgat tcattttgaa ataagactct attattacaa gttcatccgt
      301 tgtaagatgg gtataggtca tttgtactca ctccttataa ttctttggtc ggaactattt
      361 tgagtgtagc acaaatgact tttttagttg tctagcttaa ttttacaatc ggcgacttat
      421 tgcttttgca aaatttattt acctgttttc tggatcaacg atagtgtaca ttatgctatc
      481 cttgtttgga ttttaggacg tttaaagagg cactttttta cataacttaa tccatagacc
      541 ttttaagcat gctgtgagat aataataaag aagagtttaa agcgcacccc aaaccacttc
      601 cccataagtg tattacgctt taaactcttt tatatttgaa ttcactaaga agcataccat
      661 atatttgaat ttactaagaa gcataccata tttttgaaaa aaagtgagaa aaaaggctta
      721 taattaggat ttagagtaat taattagatg tttattttat aggactgata ctatagatta
      781 caaatagtat cgtatttcgc aatcttaaaa ttatcttctt actgtgaata agataataaa
      841 atttgtattt gtccttttta ggtaacttat tttaatctat atacctttct ggatcaacga
      901 aagtatactt tatatagtca taacgccgat ggtaactatg cactgtaacg ataatgctgc
      961 taaaatatct ttttacgaaa aacatcacaa ggaaaaactt aactatggta ttatctaaac
     1021 ataatttttt cggtatttaa tatttaatta ggaggtaata ttttgctttt ttatagtaat
     1081 tttatcttaa tagtagcgat attattactt ctgaatatat ggatttttga taggagtaga
     1141 aattcaagta taggttttag aactaaacga agtttgtctt ctaaaaaaaa ttgggtatac
     1201 tcacaaacta ttttttatgg aggaattgtt ttaattagtt tactttcttc aacactttat
     1261 tctttgaata ttatagatgt ttccacctca aattcaatat ctattattgg aatcattatt
     1321 gctgcaatta ttacacaact gtttttagtg tttggagaga agaaaagaag taaaaaatag
     1381 aaaaactagt gatagttttg gtgatataag aaaaacatat atgtataaaa agaagaaagt
     1441 agcttctctt tgtacatata tggtttgttt ttatggatgc cgagcttttt tataagataa
     1501 ggctaccgcc cataacgacc caaggatttg tggaactaag taaatacctg caagaagcaa
     1561 gatcagctgg gtcggtttta aaggatgata gaagtaacgc cattcagtaa aattggcgca
     1621 aaataaatag gaagtgacag tagatataat attggcaatg aataaagata taatacgcct
     1681 gttcctttga aaataatatc cagcaaaaag agataaaaat atcaatgtga tgaacccgct
     1741 tacggaatga taacgaaaat caagcagtaa ggcgaaatgc acataaggaa caaaagataa
     1801 aagcaacgga aggtttttcc agcaagtttt tatcatcttt catcaccacc taacaagtgt
     1861 tattattttg ttagttttat tgtaaattga atcctgcaat aatcaattac tttttcatta
     1921 tttctagatt aaatgaataa actctcatgc cattatctct aaaaaaaaag tttttccccc
     1981 taattttttt agatagaaaa ttgtatagta tgatgagaga aaaagtagtt tgggggaacg
     2041 ttaatgagaa gaaaagcagt aatcgatcgg ctttatttat ttttttggtt ttttcctatc
     2101 gttttgctac cttttacatg ggtaaatgct gttgtacaag gtgcggagat attaggcctg
     2161 atccaaggaa gcggatttgt ggtttctagg aattttccag ctttgattgt tttctattta
     2221 gtgataagtg taggtctctt attaccaaaa tctctgatca atcactacaa ttggcagctg
     2281 ctttactttt cttgcttatt agtatttaca tctatgtttt ctttgctgcc tcgcttgatt
     2341 atcggcccta atggtttgag cgagagtgga ttgaaggatt tagcttattc ctccatgtat
     2401 ttcttgacga tcaaaccatg gttctattta gtaattgcct catttattct tgcaacattt
     2461 ttttacttct ggacagaaat caggataaaa agtgaacgat ctgtatctat aaaaaataac
     2521 tattgatggt ggatcatcag taaaaaaaca tatgagctgc gtaaaatgca tgtttctcat
     2581 atgctttttt tattattatg taaagaatgc gaaaaacgtt tacatgattt ttacataact
     2641 taactatatt tttacagcaa ccatacgagg gatttacagt cgactgataa actttagttg
     2701 taaataagaa aggagcaata aaatgaaaaa agtattgttt actctaggta tgatgggaat
     2761 tcttttagcc ggatgcggct caggatcagg aaatacagat ggctctgcca cacaaaataa
     2821 ttcaagtgac tcaaatgaac aagtaaaaat cgttgcggta ggttcgacag cattacagcc
     2881 gttagtcgat gcagcacaag aaagctttgt acaagaaaat ccaaattatc aaatctctgt
     2941 acaaggagga ggaagcggaa ctggtttgag ccaagtcgaa gctggagcag ttactatcgg
     3001 aaactctgat gtatttgcag aagaaagaga cggagttgat gcttcaaaat tagtggatca
     3061 taaagtagca gtggtcggga tggcaccaat cgtcaataaa gatacagatg tcaaagatat
     3121 caccaaacag gaattgattg atatctttac aggaaaaatc actaactgga aggaagttgg
     3181 cgggaaagat caaaaaatca acgtcgtgaa ccgtgcaaac ggcagcggta cccgcgcgac
     3241 attcgaaaaa tggggactgg atggtgctac ccctgtgcag tcccaagaac aagattcatc
     3301 aggaacagtt cggcagctgg taagtcaaac accaggagca atcagctatt tagctttctc
     3361 atatctcgat gattccacac aagcactaag tatcgacggt gtagaaccaa aagaagagaa
     3421 tgtagcagat aacagctggg gaatctggtc atatgaacat atgtacacga acggaaaacc
     3481 ttcccctgaa gtccaaaaat tcttagacta catgatgaca gaagaaatcc aagaaggacc
     3541 tgtcaaagaa ttgggctatt taccaatcac aatgatggaa gtagaacgtg atcacgaagg
     3601 aaatatcaaa taactagcag ataaacatgc cacggtagtc gttactatta aggaaaaatc
     3661 aactatgttt ccccacatat acatttttcc tttaattgtg aaaaatagtt cctcatattt
     3721 tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttat tcgaaaaaaa
     3781 gagctacgac atagaactgt cgtaac
//
LOCUS       DAFEML010000127         3742 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFEML010000127
VERSION     DAFEML010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.133"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="LP468_002672"
     CDS             complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="LP468_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2082139.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            1228..2331
                     /locus_tag="LP468_002673"
     CDS             1228..2331
                     /locus_tag="LP468_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2082140.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            complement(2524..3591)
                     /gene="rlmN"
                     /locus_tag="LP468_002674"
     CDS             complement(2524..3591)
                     /gene="rlmN"
                     /locus_tag="LP468_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2082141.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
BASE COUNT         1137 a          748 c          637 g         1220 t
ORIGIN      
        1 gtacacggtg ttccaaaagt agcttcttcg gaaataagtt ggaatttcac aaaaattcaa
       61 gaagtaattt tcgtaaattc cttcttattt cttgaagctg attacttctg tcacaacctc
      121 tttttattat tgagaatttg gtcgaggaat aatcgttttt gccatccaaa tatccggttt
      181 gtcccagcca tttgcatttg gtaagacacc tacgatttta taacctaatt tttcatagaa
      241 ttcatacgga tgttcacgaa ggttctggat ggaagccact ttatcaaatg tatgctcata
      301 caggtccgtt tgacttaacg ttgttccatg gtctaaatca tccgtaccta aataaatcgt
      361 gattcctcct ctggaagcta cttctttttc taagtaattg actaatcgag tacctatttg
      421 gttctttcgt cgggagcttt ctacaactaa tggatgcaat tcccaacctg tgataccgta
      481 ttgagggatt gcaccaataa atcctactaa ctcatcttgg tctaccgctg ctaccgcgat
      541 tcgttctgga ttcatcattt cttctacttc ttctgccgag ctgtctccat attcttccgg
      601 ccaagtcagt ctcagtaaat cagaaagctg atctttcaat actggattat tacggtcaaa
      661 ttcactgatt atcatacgtc ttcccccttg ttcttgctta ttctaacagt ccttttgaaa
      721 aaacgaaatg ttctcgctca aaaatcttta gctaccaatc agtatctcta ttctttcatt
      781 atttatctta cttataaaat aaaaaaatta tacagaaaca ctttattcaa aataggaaag
      841 atcaggaaag ccatcaattg gaggaaaaaa ctctgtttgt tcatcatgat atagattatc
      901 ttttgcttta aaaaaaacca attatgaatt gacaaataaa acctgttttc atataataat
      961 cttaattttt agaattttta gataattaca aaaaagcaaa gggaatcggt agaaatacta
     1021 agaggaacaa aaattcatta ttgtcgtttt caatgttttt gtacttgttc gtttttagga
     1081 tacttattga tgatttcaag gtgttcatgc caccttattc atcacttatc ctgtcttagg
     1141 ttcacctcta ctccatctac agccgcagtc agatcgatca ctctttaaaa ttttaacccg
     1201 tttcaacgaa gaaagaagga aatgaatatg agtcaaagtg ttttcttacc aaattatacc
     1261 attggaacag atgcgtatga aaaagcaaat ggaatcgtca aagaatatgg gacaaaagta
     1321 gtgctgattg gagggaagac tgcactttca aaggcagaaa acaaaataaa agtagctttg
     1381 acacaggaaa tagaggttgt cgccagtctc tggtacgggg gtaattcaac ttatggaaat
     1441 attgaacagt tgatccagca tgaaagtgtc caaaaagcag acgtcctgtt tgcagtcggt
     1501 ggtggccgtg cttgcgatac tgtaaaagtc attggtgaaa aactagctaa accagtcttc
     1561 acctttccca ctattggttc gaactgttcg cccgtcactg cggtatgtgt catctataac
     1621 gaagaaggcg taatggacgg actcttcttt ccttcaaaac cacctgtaca caccttcatt
     1681 gatacagcaa ttattgccga agcacctgat aaatacttat gggcaggtat tggcgatgct
     1741 ttatccaaag aagtcgaatc tactttttct gctcgtggcg atgatctagg ctacacggat
     1801 agattaggaa tccaaatcgg aaaaatgtgc attgatcgtc tcttgactta tggtacgcaa
     1861 gcattgaaag atagtgccga cgatcgtccc tcatatgcaa ttgaacaagt cgtttcggat
     1921 atcattgtta ctaccggatt ggtttctgtt ttagttaaca ataactataa ttctgctatg
     1981 gcacactcat tctattacgg tacgactgtt ctagaaaaaa tggagggata ccttcacgga
     2041 gcatctgtca gttatggtgt actgacctta ttgatgatgg atcagcagtt cgatttgttt
     2101 gataaaatct atgtgtttat gaaaaagaac caacttccag tatcgttaac cgacatgaat
     2161 ctcaatgtca cgaccgattt agaagcaatc ttagataaag ccatggcaac aaatgatatt
     2221 aaacatgtgc cttatgaaat cacccgagaa aaatttaaac aggccattct tgacgtagaa
     2281 acttatcatg ctacacaaga aagccagcaa ggatataaga aaatcagtta aataattgct
     2341 aaaaccccca tcaagcaggc tgtcatcaaa ttgaggacat ttctttgctt gatgagggtt
     2401 tttcttgtca aaaaaagctt tatagctttc gctatagaat cttttctctt atttaagttg
     2461 aacagttcct taattaagaa aactgctcct tttatggtaa ttgaaaaaac gagtaggata
     2521 cgattatttg gcaactgttt ttttcatttg cttgcttcgc aattgtccgc aagctgcatc
     2581 aatatctgta ccatgttctt tacgtatcac acagtttacg ccgtttttct tcaatacatc
     2641 ataaaatctc aatacatcag cttttggact gcgagaatat tgatcatgtt cactgactgg
     2701 attatatgga atcaagttga catatgctaa ttttttctta tcttttaata gatctgctaa
     2761 ttgttgcgca tgctctggtc tatcatttac ttgattcaac atgatatatt caaacgtgat
     2821 tcgacggttt gttttctcta aatactcatc cacagcttcc atcaatttct caattgggaa
     2881 acttcggttg atccgcatga tcgatgttcg cacctcatta ttcggcgcgt gcaaggaaat
     2941 agccagattg acttgcaagc cgttattagc gaattccttg attttgtgtg ctaatccact
     3001 agtggaaact gtaatgtgcc gagcaccaat tgccaatcct ttggcatcat tgatgatatg
     3061 caaaaagtcc attacattgt cgtaattatc aaatggctca ccgatcccca ttacaacgac
     3121 atgtgaaacg cgttcgccaa gattgcgctc atcaaaataa tgttggacca tcatgatctg
     3181 tgcaacaatt tctccagcag tcagatcacg gttctttttg agcagcccgc ttgcacaaaa
     3241 cgtacagccg atattacatc ctacttgtgt cgtcacacaa actgacaagc catattcttg
     3301 tctcatcagt acagtctcaa tcatgttttt atcagggagt tcaaacaaat attttactgt
     3361 accatccgaa gcttcttgga cgaccatctg ttttagagga ttgatgataa aatgctccga
     3421 taatttttcg atcaattgtt tcgatagatt cgtcatttct gtgaaattac ttacacgttt
     3481 ttgatacaac cattcccaaa cttgggcagc tcggaatttt ttctcgccgt tttctataaa
     3541 ccaattgatt aattcttcat tcgtcaagcc ataaatggac tgtttttcca aagtattttc
     3601 cctctttttc tcaaagtttc gctacatact atacatgatt catttcctta atgcaatact
     3661 tcacaaataa atcgaataga actttaatct cacaaaaact aaaaagacaa gacatcatac
     3721 cgtattagaa aagatggaaa aa
//
LOCUS       DAFEML010000128         3351 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFEML010000128
VERSION     DAFEML010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.134"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(132..680)
                     /locus_tag="LP468_002675"
     CDS             complement(132..680)
                     /locus_tag="LP468_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082142.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(681..1538)
                     /locus_tag="LP468_002676"
     CDS             complement(681..1538)
                     /locus_tag="LP468_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2082143.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1824..2110)
                     /locus_tag="LP468_002677"
                     /pseudo
     CDS             complement(1824..2110)
                     /locus_tag="LP468_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2100..2429)
                     /locus_tag="LP468_002678"
     CDS             complement(2100..2429)
                     /locus_tag="LP468_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2082144.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2506..2778)
                     /locus_tag="LP468_002679"
     CDS             complement(2506..2778)
                     /locus_tag="LP468_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2082145.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(2778..3041)
                     /locus_tag="LP468_002680"
     CDS             complement(2778..3041)
                     /locus_tag="LP468_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2082146.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT          994 a          668 c          446 g         1243 t
ORIGIN      
        1 ccgttcctat gctcattttt tggatttttt aatcacgtaa ccagaaaaat aaatcccctc
       61 tatttcacgc aaatcaaaga agaactaagt aactaccgtt taaaggtagt tacttagttc
      121 ttctttgatt attatctaac tttattattc attccccacc ctttgcgcag tgagtcttcg
      181 gtatcttgtt ttatctgact ggtagttctt attatttctc cacgatcatc taattctgga
      241 acaattggat atttttctct gaacaagtct agttctttca ccacgtcatt aaacaaatct
      301 tgcttatctt cttgcgtaag attctgttta atatactcat ctaaagcttt tctaagcaat
      361 tcatctcttg tcatattagt ctcatacttt tctactaaaa ctctggaagt cgcatttaac
      421 aaagtcgaca gttttaaagg atgcttggtg gaataaacct tatcaaactt tctgattggt
      481 gcgccaactt tttttgttct tcctctactc tgtctttcaa cattggagga agtttttatt
      541 tcttgaactt ggtgcacttc taattgctta ttttcagatg gtgtaattgc ttgctgcttt
      601 ttctttgctt ctgcttcttt ttttattttg gcgagtcctt tgttgttccc aaaaatatca
      661 agtcctttga tgtcagccaa ttactccacc tccgcatacc aattctcgtg ttcttccaat
      721 tctttcaaaa tactgataaa taattcgtgg cttttgcgat cccattgttt taagagacct
      781 ttctttgtct tctccatcgt aatacctgat ccgtcgtatc gttttaagcg cgcatttttg
      841 agtacaacat ttttaatcaa atgttcccca taaatctctt gggcttgttt atacatttcc
      901 tgatctactg cgtcaccgct ttccaacatg aaaggaataa caccagcaac atataaattt
      961 gtatcaaatt ctttcacaaa aaagtccata tactcaagat attgcatcgc atttctcatc
     1021 gattttactt gggtctgtaa gacgacgatt gcccaatccg caatgtacat cgcggattta
     1081 ctatatacag aaatagaagg tgggacatct aaatagatga cgtcaaactc atcaaataat
     1141 ggttctagct tttctttcat atatttgaat tgggataatg aatcattata ttggtctttg
     1201 atccaatcat catacatttc aaaggacatg tctgctggaa gtatatagag gttattgatt
     1261 actttataga cagcctcttt aggtggaaga ttgtttatca acacgtcagt cacagtattt
     1321 tcgtaaacaa tcggttcacc ttctccgcct ccttcttcgt tagtgaagtt catatgcgtt
     1381 aagttcatca catcagaagt atttccttgc atatccaagt caattatcaa ggttcttttt
     1441 ccttcattaa ctgctgattc aaaccctaac atttgcgcgc acgtactttt acctacgcca
     1501 cctttaaaat taccgattac atatttcttc gctaccacgt tcctacctct tttcttttag
     1561 caatattcat ttgatactat tataacatat ttatttttag ttactaccaa aaaaaagata
     1621 tatatgtact accttataat taataagtaa aaggtagtac ataaataagg aaaagctgaa
     1681 atatattgat ttatagcttt cctcaaagta atgacgttat ttaatttatc gagaagcaga
     1741 gaatactcgc gactttagtc atgtagacga atcagatttt cgataaaaaa gaagccgtcc
     1801 ttcttaagaa cgacaacaaa tcactagatt aattttttca actgttcata aaagttttca
     1861 tgcgttccac ataacaatac tggaataacc ttgttttcta taatctcgta agctactcta
     1921 tatgttgtgc ccgcatattt gaacccacta gaccaaatac ctgataaatc cccagttttt
     1981 tgttcaccct tatatggatc aatcgcaatt tcatcataaa ttaaattcaa aaatttttct
     2041 ttcaatggct tctcttttag ctttttaaat acttaatgac atgttttgaa ggaacgattt
     2101 cataagccaa tttctgttgc caactcctct ttagtcatta ctttagaatt agtaagtgta
     2161 tcttcagcaa tatctctaaa ggaagaatgc attttgtttt ttctattctt aaattctaca
     2221 agaatctcat ctttatcgta gccttctgca attatatcag acaaaatatc ttcgctaaaa
     2281 tcataaaatt ctttttgtgg ttcaacaaat tcataaagaa taccattctc taccaacttt
     2341 gcttcaactt cgactccatt aggaacatta aaatctttag gtactgtcaa catgattgaa
     2401 ttgccttgtt ttcttgtttt tgtaatcatt taaatccctc atttctaaca gtatgtaatt
     2461 acttagtaaa tacattatac cacgagataa tgtatttaca agtaattact gtgactcgta
     2521 atgcgtcctt gctgaataaa tttcaaccac gtgttcatct tcatctacct tataaacaac
     2581 ccggtgttgt ctattcaatc ttctagaata cctaccttca tgtgtaggtt ttaacttctc
     2641 aaatgattgg gtagggagat agggatcttc ctttaaagtc tgaataacct tctcaaattg
     2701 aggtttcaaa ttagactgtt tgattttctt taaatcagct ttagccgagt ttttaatcat
     2761 cacagaatag ttattcatta taagttatcc caatcaattt catcaacatt agtaaatcca
     2821 ctatcatctt tttctcgctt acgaacaaca cccaaagtgc ctatttgctc aagtaatagc
     2881 gtttctttga ttgctttcca atcatccaaa ccaataagca ccgcattatt ttcactgcgc
     2941 tcactaatga tttcaatttc cgtatgattc tcatttacat ctttcaacaa cttataaaaa
     3001 tttttccgtg ctgagctagg atttaagact gtttttgcca tatctactcc ccctctaatt
     3061 tatatctcca ttctaacgta cttaattaag tacgtaaatt cgattgtttt gtttaaattg
     3121 gagtaccaaa acagcattgt aaagtgttat ccgtttcctt tatacccgtg gtgctagtta
     3181 attttttcct agaggaaaat gtctaaacat gttggtaaat caacaaaaaa acgcatagag
     3241 tagtctcaaa actcccaaga aatgaggact acatatgcgt tcatcaaaat atactgaaca
     3301 ttatacagat acttttataa cattcaagga aattatgaga actgtttcta a
//
LOCUS       DAFEML010000129         3218 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFEML010000129
VERSION     DAFEML010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.135"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            49..1437
                     /locus_tag="LP468_002681"
     CDS             49..1437
                     /locus_tag="LP468_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBL2082147.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1775..>3218
                     /locus_tag="LP468_002682"
     CDS             1775..>3218
                     /locus_tag="LP468_002682"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL2082148.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          583 g          947 t
ORIGIN      
        1 tcaaaaaaaa accaaccgaa agatataaaa gatattgtag atacacgaat gtataaagaa
       61 cgtgatgact taaactatac gcttattatc aataaagatg gaaactattc atggcgtcct
      121 ctcgttctac tacatcctat tctatatgta gatttggtta attgtctcac taaagaagac
      181 cattgggagg agttaaaaaa gaggtttagt gaatttaaaa aagataaaaa tattaactgt
      241 tattctatac ctgttgaagc ttccaaaggt tcaaaaagga cagatcttgg tgaaacaata
      301 ctaaactggt gggaatattt tgaacaaaaa agcttagctc agaatattaa ataccaatat
      361 tgcatgttta ctgacatcgc tgattgttat ccatcaattt atactcactc tataacatgg
      421 gccatgtatg gtaaagaaaa agttaaaaat gatgaaaata agtgttcggg ctcacttggc
      481 gataaaatag ataaaaaaat atctggaatg caacacaatc aaacaaatgg tatccctcag
      541 ggttccgttc ttatggattt tgtagcagag atcgttctag ggtatgttga tttgagatta
      601 tcgaaagaat taaaaaaatt agaaaattta aaagattaca aagtactcag atatagagat
      661 gattatagaa tattttcaaa taatcgtaat gatttggaac aaattatgaa agtgttatca
      721 gaagtcttat atgatttaaa ttttaagtta aattctagta aaacaaaatt atcagatgat
      781 attatcatag attctatcaa aaaagataag ctctattggg aagaaattaa ggcaagtata
      841 agaatgaatg ccacaaactt agatggtgat agagaaattc gttatagtat aaatttacaa
      901 aaacatttat tggaaataaa aaagttagca gataagcatc ctaattcagg ccaattgaaa
      961 aaagcacttt ctgagtttaa taaagaacgc attattaaaa tcacttcaaa gccgaacgat
     1021 cttttaccac ttattggtat cctggtagat atcatgataa ataacccggg ttctttgccg
     1081 cagtgtgtct taattatagg gcagttatta aatttcgaaa atgagagtaa ggctagagaa
     1141 atagttgaaa tgattataaa caaatatgct ttaaagccaa atactgaatt tatgatgata
     1201 tggtttcaaa gattgaccac catttttgga gaaatgtttg atagtgtttt atcatccgaa
     1261 tttgtatcta aaatcaaaga tcctgtctct aatcagatgt tttctgtaga ctggctaaat
     1321 gaagatgcta agaaatcttt ttatgaaggg accattaaag acgaagagaa atatattaaa
     1381 atgagtaaga aaatatatat tactgaattt gatgatttta atgattatcc tttttaagtg
     1441 aaaatttaga atgaatataa aaaacattac aatctaattt ttttaaaaaa atgttatatc
     1501 ggaagtaatc tcttgatttc tatactataa gataagaaaa ccactattta acaaggttat
     1561 tcgaacctta ttttaagtta cttattattt aatgtatcga aaaaggtgaa ataggtttgt
     1621 tataataaga attaagtaag acatgaattg tctaagcaaa tgtagcttat ccatttcatt
     1681 aaaatacata tggtgaaaaa acaagttcaa atagtaacta attttttaaa aaactgattt
     1741 ataaaaaata caacacgaat gaggaaaata accaatgaca gaacaaatcg aaaaaaattc
     1801 aaaaagctta tatcaggcac tgtggaattc cgcagatatc ctgcgttcaa aaatggacgc
     1861 taatgaatac aagagctatt tactaggctt ggtcttttat aaatacttat ccgacaacat
     1921 gctgcggtat gtctccgttc tattggagga agaaacggac gacctaaata aagcacaaga
     1981 cctttacgtt gaagcattta aagatgcaga tataaaggat gatctcttgt atgaactaaa
     2041 agatgagttt tcatatacca tcgcacccgc attgaccttt accgcgcaag tggcagccat
     2101 tcatgatgga tcttttcaat tagaagacct ggtacaaggt ttccgtgaca ttgaacaatc
     2161 cagcgaaaac tttgagaact tatttgaaga cattgatctg tattctaaaa aactggggtc
     2221 aaccccacaa aaacaaaata aaaccatcgc agatgttatg aaagaattag aagggttaaa
     2281 catggcgggg catgctggcg atgtcttagg cgatgcctat gagtacttaa ttggccaatt
     2341 cgcatctgaa tccggtaaaa aagccggtga attctatacc ccacaaccgg tcgcaaaatt
     2401 gatgacacaa attgttttac aaggaaaaga agataaaaaa ggcttttctg tttacgacgc
     2461 gaccatgggt tcgggctcgt tacttttgaa cgctaaaaaa tattcccatc aaccgggaac
     2521 catttcttat ttcggacaag agttgaatac gtctacctat aatttggcgc gtatgaacat
     2581 gattttgcat ggggttccca ttgccaacca acacttgcat aatgcggata ccttggatca
     2641 agactggcca acagaagagc caacgaactt cgatggggtg ctcatgaacc caccgtattc
     2701 tgcaaaatgg tcggctgata aaggcttctt agatgaccca cgcttctctg cctatggcgt
     2761 attagcccct aaatcaaaag cggactttgc tttcttatta catggctact atcatttgaa
     2821 agatacgggc gtcatggcca ttgttttgcc acatggggtg ctctttagag ggggcgcaga
     2881 agggaagata cgcaaagcct tgttagaaaa tggtgccatt gacaccgtca ttggcttacc
     2941 tgctaacatc ttctttaata cgtccattcc aacgaccgta attatcttga agaaagaccg
     3001 tgcgaaaaaa gatgtgctct ttattgatgc gtcacaagat tttgaaaaaa taaaaacgca
     3061 aaatacgcta cgagattacc atattgacgc tattttagag gcctataaaa cccgtacaat
     3121 taaagacaag tatgcttatg tcgcagaatt tgatgaaatt gtggagaatg attacaactt
     3181 aaacattccc cgttacgtgg atacctttga agaagaag
//
LOCUS       DAFEML010000130         3209 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFEML010000130
VERSION     DAFEML010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.136"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            116..976
                     /locus_tag="LP468_002683"
     CDS             116..976
                     /locus_tag="LP468_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBL2082149.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            988..1815
                     /gene="panB"
                     /locus_tag="LP468_002684"
     CDS             988..1815
                     /gene="panB"
                     /locus_tag="LP468_002684"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBL2082150.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1830..2678
                     /locus_tag="LP468_002685"
     CDS             1830..2678
                     /locus_tag="LP468_002685"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBL2082151.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2688..3083
                     /locus_tag="LP468_002686"
     CDS             2688..3083
                     /locus_tag="LP468_002686"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBL2082152.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
BASE COUNT         1246 a          327 c          642 g          994 t
ORIGIN      
        1 gatattatga taaattaact atggatgata tttgaaaaaa acatactgta tatttgattt
       61 aatttttatt tttaagctca tatcgtaaga atgggacttg tagtctcact tctttatgga
      121 ggtgataatt atgaacgttg gttttattgg agccggcaag gtaggttgtt cattcgggaa
      181 gtatttccag gaacataaaa tacaagtaac aggattttat agtaaaagcg aagactcgtc
      241 attagcagct tcgaatttta catctagtaa acaatattta aacttaagag aattagtaga
      301 tgaaaatgat actattttca ttacgactcc tgatggtcaa attcaggagg tatggcaaga
      361 aattaaaaat tatcaaatca aaaacaaatt aatctgccat tgcagtggtg caatatcttc
      421 agatatcttt tcaaatatac aggactatgg tgcttatggc tattctgtcc atcctatgtt
      481 ttcaatatca gataaatata attcatacaa aaaattaaaa aaatctttta taacaattga
      541 aggcgatgaa aaatatgcaa agtttttatg tgatttcttc aaaaagttag gtaatagtac
      601 tgtaattgta tctaaggaga ataaatctct ttatcatgcc gcatcagtag tatctagtaa
      661 ccttgtgcta ggacttatta atacaagcgt tacatatcta attcaatgtg gatttactga
      721 aaaaatggca attgaagctt tatatccatt aattgaattt aatattagaa atataaaaga
      781 aaaaggaatt atagaaagtt tgacagggcc agttgaacgt tgtgatattt caacaattaa
      841 aggtcactgt gaagttttat cagatgaaga cagagcttta tatatgctat tatcaaaaaa
      901 tgtattagag atagctatgt taaaaaatat taatagagat tatagtgaat tagaaaagta
      961 tttaggagag agttaggaga gaaatagatg aaaaatacag cagttacatt taaagaatct
     1021 aaattaagaa atgaaaaatt aacaatgctt acagcttatg actattcaac agcaaaaata
     1081 attgatgaag ctgggataaa tggaatatta gtaggagatt ctcttggtat ggtatgtcta
     1141 ggacatgaag atacactttc agtaacaatg gaagacatga ttcatcatac tagagcagtt
     1201 acaagaggag ctaagaacac tttagttgtt gcagatatgc catttatgtc ttatcaaact
     1261 tcagtatatg attcagtagt taatgcagga agattaataa aagaaggacg agctcaggtt
     1321 gttaaattag aaggagggat agaagtatgc gataaaatag aggctatagt aaaggcttct
     1381 atacctgtta tggcgcatat aggtttaaca cctcaatctg ttaatgcatt tggaggattt
     1441 aaggtacaag gaaaggacaa ggaagctgct aaagaattaa taagagctgc taaagctgta
     1501 gaaaaagcag gagcattcgc tgtagtgtta gaatgtgttc caactaagct tgcagagtta
     1561 atttctaaag agatatcaat acctacaatt ggtattggag caggtgcagg gtgtgatgga
     1621 caaattcttg tatatcaaga tatgttgggg atgtatagtg attttacccc taaatttgtg
     1681 aagaaatatg ctaatttatc agaagagatg aataaagcat ttacaaaata tatagaggaa
     1741 gtaaaagatg gagtttttcc aggtccagaa catgggttta aaataagtga tgatgtttta
     1801 gaaaaattat attaaaaggg tcaagaaata tggttatatt taaaacagtg aatgatgtta
     1861 gaagtcaagt aaaagagtgg aaaaaacaag gcttaaaggt aggattagtt cctactatgg
     1921 gatatttaca tgaaggtcat gaaagtttaa ttagaaaagc atcaaaagaa aatgataaag
     1981 ttgttgtaag tatctttgta aatccaactc agtttgggaa aaatgaagat ttaggtagtt
     2041 atccaagaga cttagaaaga gatatagaag tatgcacaag aggtagagca acagcaatat
     2101 ttaatcctga agttgaagag atgtattgtg acaatgcaag tacttttgtt aatataactg
     2161 gattaacaga aggtttatgt ggagctagta ggccaataca ttttagaggg gtttgcactg
     2221 ttgtaagtaa attatttaac ataataccag cagatagagc ttattttgga gaaaaggatg
     2281 cacaacagtt agctgtaatt aaaagaatgg ttagggacct taatattgat atagacgttg
     2341 tagggtgtcc aattataagg gaagaggatg gactagctaa aagttctaga aacacatact
     2401 taagtttaga ggaaagatct tcagctacta ttttaaataa atctttaact ttagctaagg
     2461 aagctttaaa taatggagag agagacagct taaaaataat tgagataata agtaaaaata
     2521 taaatactta taatttggca aagattgatt atgtagaagt tgttgattct ttatcattac
     2581 aaagagtaaa ttatattgaa aaatcagttt tagttgcaat agcagtattt ataggaaaaa
     2641 caagattaat agataatttt acatttgaat tacaataggg ggctataatg aaagttacaa
     2701 tgttaaaagg aaaaatacat agagctacag ttgaacaagc tgagttagat tatgtaggaa
     2761 gtattactgt tgatatgaat ttattagaag cagcaggaat atatgaatat gaaaaagtac
     2821 aaatagttga tgttaataat ggaaatagat ttgaaactta tacaatagct ggagagagag
     2881 gaacagggat gatttgcttg aatggagctg cagctagatg tgtatcaact ggagataaaa
     2941 taattttaat ggcatattgt gaattaaatg aaaatgaggt taaggatcat agacctaagg
     3001 ttgtttttgt cgatgataat aataaagttg aaagagtaac atcatatgaa aaacatggaa
     3061 ggttatcaga tataattctt taggttttgt aatgttattt atatatagct agactattat
     3121 tgaaatattt attgattact aattggatag atgtcaataa agtagacaca aaaagagaag
     3181 atacagactg tagacaaagt ccattttat
//
LOCUS       DAFEML010000131         3168 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFEML010000131
VERSION     DAFEML010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.137"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            14..175
                     /locus_tag="LP468_002687"
     CDS             14..175
                     /locus_tag="LP468_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082153.1"
                     /translation="MKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            172..1476
                     /locus_tag="LP468_002688"
     CDS             172..1476
                     /locus_tag="LP468_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2082154.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            1572..2441
                     /locus_tag="LP468_002689"
     CDS             1572..2441
                     /locus_tag="LP468_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2082155.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(2553..2873)
                     /locus_tag="LP468_002690"
     CDS             complement(2553..2873)
                     /locus_tag="LP468_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL2082156.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            3043..>3168
                     /locus_tag="LP468_002691"
     CDS             3043..>3168
                     /locus_tag="LP468_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2082157.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVY"
BASE COUNT         1055 a          604 c          627 g          882 t
ORIGIN      
        1 tgaagatgaa aaattgaaaa aaagacaaga attacttgaa gaagtgtata cggaacgttt
       61 tggaacaaaa gaagagagag aaacggtccg tttttattct gtctccgaag agaaaaatct
      121 agatacgaca ttcattgcag atttgtataa agaaaatggg gtggaactga aatgatctca
      181 atcacccata caggtaattt attcttagat acttgtttgt ctattatgta tttttttctc
      241 gtttcttatc cgattttagg cggatttgta tggtttattg gtgtctggtg ttatgtgttt
      301 ttatacaaac ataagcaaaa agaatgggta gatgttccct tgagtgtcga accgttcatc
      361 acgatcatgg tgccagccca taatgaagaa attgtgatcg aagatacaat cgagtatttg
      421 atgacgaaat tgaattatca caactatgag gtattagtga cagacgatgg ttcaacggac
      481 caaacaccag aaatattagc tagactgatg aaaaaatacg ctaatcttcg tgtggttcgg
      541 atcgaaaaaa ataaaggaaa agcccacgcg tttaatatcg gacttgcctt tgcaaaaggg
      601 aaattgattt taagcaatga tgcagacacg gtaccggagc cagatgcact gattaggtat
      661 gtgaattatt tcattcgccc tggtgcaaga catattgctg cggtcactgc aaatatggat
      721 gtccaaaatc gtaccaaatt gattgcaaaa tctcaaacgg ttgaattctc aagtatcgtg
      781 ggcatcatta aacgaacaca gtcagctgtt ttcggtggtc tttatgcgta cagtggagca
      841 aatacgatgt atcgaaaaga agccttgatc gatgtgggcg gattcagaca agatcgagcg
      901 acagaagaca tcagtattgc ttgggatcat cagttaaatg actggttatc tgtttttgct
      961 cctgagatta tctttttcat ggaagtacct gtgacgttga agatgctata tcgacacaga
     1021 aaacgttggg caaaaggtgg aacagaagtc tggctgacga atttcaaaaa agtgatgctc
     1081 catcctttta aacatattgg aagaacgatc atcttcattg atcaaacatt gagtattgtc
     1141 tggtcaatat tcttttgtat ttccgtagtt ctttttgctg gattaatcgg gcattatgta
     1201 tatcaaggaa actacgaaca gatttatatt acttttacat tcagttttgt gttcatctgc
     1261 tttgaaatgg tcgcaggatt tttccagttg ctagcttcgc tgattgtaga tgatcgacga
     1321 agaaaattga aataccttct tttcgcacca ctatatatgc ttttgttctg gatagtgaac
     1381 gcgataacga tcgtgacgac tttcattcca gcagtcaaaa cgattttagg ttatggaagc
     1441 gggacatgga aaagcccgga acgtacaaaa aaataaaaga tgcaccgttt tttagacaaa
     1501 cagcctgttg tgtttatggt tcttccaaac atttttgctt ataataagaa attagttaaa
     1561 aagtagtaag gatgggaaaa gtgatgaaaa aaagaatgaa gccgttaatc tggccaattg
     1621 ctgtttccag tattttctta ttgggacaga cagcttttgc ggaaacttct gaacctgctc
     1681 aaacagaacc ttcaacaacc ataagctctt ctggtgctga aaacggtgcc tcggaaacag
     1741 aaatgacttc caatgtaccg acagataatt caggagaaac gatttcatct tcagaagata
     1801 catcaataaa tagttctacc tcttctgacc aaatcgatca tttgcaagac ttggaaaata
     1861 aaagaaaaga actcgaagaa gcattagaag ctgcaaaaaa caaattgaaa gaagaccaag
     1921 cagcaatcga tcaagattta gctgatctta aaaataaagt gggaaatgac cgtgcacaac
     1981 ttgagaaaaa gcttgccgaa gcgaaagcaa aagcggaagc tgtccaaaca gatcttgacg
     2041 ggaagatcca acaagcaaaa gaattcaatc agcaattaaa tcaggttgct caaacagctt
     2101 ctggaaagct aagtcaaact caagcggata tcacagcggc cagtcaagca atccacggaa
     2161 agatcagcga agcacaaaca gttgctaatg attttgaagc aaaaaaagct gacttagcag
     2221 ctagtttcca acgaataaaa gatattttgc attcggcagg agaaaaatca gtgacctctg
     2281 gaagcacgac agaaacagtt cagcaaacga cagagccatc caaatcaaca agtcagactt
     2341 tgccaaaaac aaatgaaaaa acagcttctg tcagttattc cttagcaggg gcgggtgtgt
     2401 tagtcgcagc agcttacgga atcatccgca aaaagaaata aaaaagagag gatgggaagg
     2461 tagagtacct cgaagttaga ctgaaaaatc taattcttga gtgccactac atgtcccatc
     2521 tctctttagt tattaaaaca gatgtcccct acttatctcg tggagacagc tgttccacta
     2581 catgtgacca tcagcatgcc attgtcgctg cctaatactt catagtccat ttttacgcca
     2641 atgatcgcat cagctcctaa tgcttttgca cgttcggcca tttcggcaag tgcttcttct
     2701 cttgcaccca ttagttcgtt ttcatagctt tttgagcggc cgccaaagat atttcgcaac
     2761 cccgcctcca agtctttaaa tgcatggatc ccagtaatga cctcaccaaa aacgatccct
     2821 ttataagcta ctacggcttt tccctctaca ctgttcgttg ttgttgtaat cattcgatca
     2881 ctcctctctt ttaattaaag tataacaaac ttcaagaagc actacacata ttttcccaaa
     2941 attagaaatc gccgattgta aaattaagct agacaactaa aaaagtcatt tgtgctacac
     3001 tcaaaatagt tccgtcgaaa gaattataag gagtgagtac aaatgaccta tacccatctt
     3061 acaccaactg aactcgtaat gatagaagct tatttcaatc aatcacactc tgtttcaaaa
     3121 gtagcccatc tggtacaacg ttctcgacaa accatttata atgtctat
//
LOCUS       DAFEML010000132         3102 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFEML010000132
VERSION     DAFEML010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.138"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(33..743)
                     /gene="budA"
                     /locus_tag="LP468_002692"
     CDS             complement(33..743)
                     /gene="budA"
                     /locus_tag="LP468_002692"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL2082158.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(756..2420)
                     /gene="alsS"
                     /locus_tag="LP468_002693"
     CDS             complement(756..2420)
                     /gene="alsS"
                     /locus_tag="LP468_002693"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL2082159.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(2625..3092)
                     /locus_tag="LP468_002694"
     CDS             complement(2625..3092)
                     /locus_tag="LP468_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082160.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT          916 a          682 c          507 g          997 t
ORIGIN      
        1 taatcacctt gaacgcatct cgctgtcttt ttctattctg cttgttggat ttctgctgct
       61 aaatcagcat aatcaatcgt ttcgtgaaca aaagtcggat catcaactgg aaaatgctgt
      121 acaagggacg agatgcggct aatctcaact tttccttcag ccacttcaaa atccattaca
      181 tgtccgccaa atgtatgtgt atcatcgata aaatgcaagt gaaatcccgc tgcagcaact
      241 ccttggaata attcaggcgt aaagaacccg actaatgttc cttggacatt gctttgttgg
      301 aattctggtt gagactctga aatttttgct agtcttctgt aaggtttttc ttgcttcggc
      361 atgatacgga tgtgcatatt tttgaataat ccagttatct tcactgccaa aaataggttt
      421 tccccggctt ctcttactaa tatgtctttt ttcaattgtt ctccatctgc agtttttgag
      481 acagaaaaac tagtatctgg cgtaaaatct gtaattgctg catagggggt aagttcactt
      541 ccatctaatt gggcaactga gccatctgat cttccttgat aagctacgcc atctaaaaag
      601 atgacttcac catcaagccc atgcaatgtt cccaatccca gagttccttt ttctaatata
      661 tgagcaatcg tttctgttcc atccatcaag ccagccatca aagctcctaa tgtcccgtgc
      721 tggtataaga ttttttcagt catgtcgaca cttccttaat agaattgatc tggtaagatt
      781 gtttctccca atttctcatt atcacggtaa tcaatcggaa tatcaataat tacgggtcct
      841 tctgtcgcaa atccttcttc taaagctttt tctaattcct ctacacttgt agctcggatt
      901 cctttagcgc caaaagcttc tgcatatttc acaaaatcaa ctggaccaaa gtctacacct
      961 gacgcccgct gatatttcat tttttcttgg aactctacca tattgtagtg tccatcattc
     1021 caaatcaaat gaacgatatt caatttttta cgtaccgccg tttctaaatc ctgggcagag
     1081 aataaaaatc ccccatcgcc ggaaactgat acgatttgtg tatttggacg caccaatgca
     1141 gcagaaatcg cccatggcaa tgcaacacca agcgtttgca taccattact gaataacaaa
     1201 tgacgaggtt cataacttct aaagtggcgt gccatccaaa tataatgact acctacatct
     1261 acggtaacag tcatatcatc tgttactttt gactgaagcg tgttaataac ttctaaagga
     1321 tgcaagatac ctgcttctcc ttttgattga acaatgtccc gctccgttaa ttctgcttga
     1381 agagatgcta aatattcttt tgcatcttct gacacttgtt gaggctctaa tgaacctgtc
     1441 aataaatcaa gagtggctga gatatcaccg atcaattctc tttcaggctg cataaaagga
     1501 tcgatttcag ctggcgcttc atcgatcaca atgatccgcg catctttttc cgcattccag
     1561 tttcttgctt catattcgat tggatcatag ccaatagcaa taactagatc acttcgtttc
     1621 aaaagcatat ctcctggttg gtttctaaat aaacccacac gaccaaagaa atgcgcttct
     1681 aattcacgtg agatcactcc agctgcttgg aatgtctcta caacaggcaa tgctgtcttt
     1741 ccaactaatt gcctgatggc taacgtttct ttttcacttg atcctcgcat acctactaat
     1801 agtaccggta gttttgcttc tctaatgcgt tcagctaggt aacggatatc atctgcagaa
     1861 gcagaaccta atttaggatc gctcaatggc ttgatgacat tcccttggac aggtgcatcc
     1921 actacatctt gcgggatact gataaagctc gcgccttttt ttgaactctt agccatacga
     1981 taagcattgg caatcacttc tgaaattgtt tctggatctt ggatttctgc actgtatttt
     2041 gtgattggct ggaacagtgc tgcattatcc atgctttgat gggtcaactt caatagatcg
     2101 cttcgtttta cttgtccggc aattgctaaa actgggtcac cttctgctgt cgctgttacc
     2161 aaacctgtag ctaagttact agcaccagga ccacttgttg cgataactac tcctggctct
     2221 cctgtaatac gtccgattgc ttgtgccata aatgcagcat tttgttcgtg acgagtcacg
     2281 attaattcag gaccttgatc ctctaattca ttaaatacac catcgatttt tgcacctggt
     2341 ataccgaata cataatcaac atgatgatta atcaaacttt ctactacaga tttcgaacct
     2401 tgtttcattt tttcgtccat tgaacatcgt cctttttatg ctttattttt aattattagt
     2461 tagaaataat cacaaataat tgatacagtt tctaaacctg tttcattcaa aagtatagca
     2521 cgttttattt catttgttta gccatatgtt tcaaaaaatg aaaaagaatg acagttttta
     2581 cataaaaact gtcattctta attgaaagtt tcaatttata aagtctacag atccatagtt
     2641 ctcatcaatt tacgattgtt gaagtaaatc aaaccaaata cgatagaagg acctagtaga
     2701 atacaccatt ggggctttac gaaaaagaag agaaacaaac ttgtcaatag taaaaaatct
     2761 agtaaactca cataccattt tttcaacgta tagtagaacg ctatccgtag aacttgattt
     2821 ggtttcgacg ctggatttct cacctgaaaa taccagtagt tgatgctaaa ggaaactgat
     2881 aaacaagcaa gtaaaacaaa caacggaatc aaccattttc cataagaaaa acgtataaaa
     2941 aagaaacaat caaaaatcat tatcacacta actatccaag caaatagcca ataaaaaaat
     3001 ccctttagcc aaaattggcg aaacgtcttt atgaacaaac gtactggtga aaaacttttt
     3061 tcttttgcta attcttctgt catacctatc atcacgatgc aa
//
LOCUS       DAFEML010000133         2739 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFEML010000133
VERSION     DAFEML010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.139"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="LP468_002695"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="LP468_002695"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2082161.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1072 a          425 c          558 g          684 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatata
//
LOCUS       DAFEML010000134         2670 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFEML010000134
VERSION     DAFEML010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.140"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            1164..2183
                     /locus_tag="LP468_002696"
     CDS             1164..2183
                     /locus_tag="LP468_002696"
                     /inference="COORDINATES: protein motif:HMM:NF019371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HBL2082162.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQE
                     MIKKISKDIFLTNSDTILLEKFLKKNSYFRFSIYVKLMKNIDKVTILDVIETYKLDSF
                     IRNQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQCYLDKNIYSDLKWAEDIIGH
                     FNSFFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLTTFINQLNTEYYNNWVMSCY
                     DNPKYKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPTIIKNDSKSYFPENNLKETQ
                     KLYLYGGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDKIPSLEKSNYGFPENWRNKL
                     KIMIV"
BASE COUNT          943 a          419 c          445 g          863 t
ORIGIN      
        1 taaattcatt tctactgacg taaatttgcg taaaggaatc gtatttaatt catggtggta
       61 tttcacaatt tcatttgcca taaaatcctc cttcaagatt aactacttaa caaaattata
      121 aagagctttc taataggggt caagccccta attaaagacc cctaaaaaca gacaaaaaga
      181 cccccaaaag attctgcaca ccttgggaga gtaagcatac agccgacggt aaagaggttt
      241 aaaaagaggt ttaaaaagag attataaaag aggagagggg caaaatttcc cgcctaaaaa
      301 ttttctgctt ttttagccaa acaggttcgc gaattttact aaactgggaa acttgctccc
      361 tctggtcgct aaaaaggtgt gagggaaaaa caccctcaca ttgtacctgc gcagtcgcct
      421 aaaggctcct ttgctaaaaa cgttgtttaa agagattttt ttagaggctc tgcgcgctcg
      481 tttaagccgt tttaagacag tttagtatgg ataaccctta tcttgttctt aaagcacctt
      541 acaggcggtc agggcaagcc ctaacaaccc ttaaagagca taaaaccatc ctaaaattcg
      601 atttaatctg tcttatctat gttcttgtat attttatata ccttgggtag taaaacgtct
      661 gaaaacgcaa ataagagcgt atgaaacaaa acaataagca accgattcag cagaattccg
      721 gaggagccat tttcgtacgt tagcaaaaaa gtgctgttgc taaaagctgc ttgcggtgcg
      781 gagcgaacaa ggtctcctag agcgagacgt gtacaaacaa gcttacaaat tcgtgaaagg
      841 caccggtttt gcgccatttc caagcaaaaa aaggtctatc gagcaagctc gatagaccga
      901 tcgcatttag ccccccgcat tctaacaggg ggggaataat gtgaaaaatt atggtagtaa
      961 tgcttgatat ataggcattt cttttggttg cacacttaaa aaaaatcacg attttgacaa
     1021 ctaaattttt aaataaaaaa gctttacagt ttaattcaaa tgtgttttaa tatatctatc
     1081 agtacttgcc acgcctctga tttaatatca tgcgcattat ggtagggctt tttttttata
     1141 tttttttaag aaagaagatt cttatgaaga catcaaatag aaaatataaa gttaaaacag
     1201 ttaatcatag aattccacct aaaaaggcat tatgtgtaat taataattcc aaagtaatta
     1261 atcaagagtt aaaaccatat ttatccgagc aagaaatgat aaaaaaaata agtaaagata
     1321 tttttttaac aaattccgat acaattttat tagaaaagtt tttaaagaaa aatagttatt
     1381 ttcgatttag tatttatgtt aaattaatga aaaatataga taaagttact attctagatg
     1441 ttattgaaac gtacaaatta gattcattca ttcgtaatca attgcattat tttgtgaatc
     1501 aaatagaaat tttttggaaa aaatctcttt cagataatat gtgcgtttct tatgaagaaa
     1561 ctagcatatt tccgaagaat cagtgttatt tggataaaaa tatttattca gatttgaaat
     1621 gggctgaaga tataattggt cattttaata gtttttttta ttcaaatcaa agtcccactt
     1681 ttaaacatca tcatataaaa aaaaatcatt gtttaccaat atgggcttta tttgaagaaa
     1741 taacatttgg tagtttaaca acatttatta atcaacttaa tacagagtat tataataatt
     1801 gggtcatgag ctgttatgat aatcctaaat acaaaaaagc tatacgaagt tgggcaaacg
     1861 taattagagc ttatagaaat aagatagctc atcattcaag aatatatgca tttaaagtta
     1921 ctgacgctcc aacaatcata aaaaatgatt ccaaaagtta ttttcctgaa aataacttaa
     1981 aagaaaccca aaagttatat ttgtatggag gattatacgt tataaaacat ctgttaatat
     2041 atgaagatag catgacacaa actttatgga ataaatttct aatagattta gaaaaaaaga
     2101 tcgataaaat cccttcctta gaaaaatcca attatggttt tccggaaaat tggagaaaca
     2161 agttaaaaat aatgattgtt taattgttat ttaaattgtt agtagacata atgtacatac
     2221 taccaagtag cccctggatc aaccgatcca ggggaagact ttgtgatttt caattggtct
     2281 atctaaaaca tctttttaaa agcttgattc ttcgctgttg gcttttttcg attctttgtg
     2341 aatattcagt gattattttt ttactacttg ttattttccg agggatttgt taaaagttta
     2401 atagcgtttc tcagtaaggg acgtcgtttt ttcattttcc tatgtatgga ctgctcgaac
     2461 gagcagcctt tttttattcc agggaacgtc ctattctttg agtttccatg ctattgaata
     2521 accgggactt agggattagg gcagcgcccc aaaatgaaaa aagaaaaatc cgcttctgcg
     2581 aattcttctt ttttttcgca agttggtacc aacttgcaaa tcttgctgga agaccgatcc
     2641 ctaaaaagaa atcgaggaat ttttttgttt
//
LOCUS       DAFEML010000135         2635 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFEML010000135
VERSION     DAFEML010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.141"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            6..1151
                     /locus_tag="LP468_002697"
     CDS             6..1151
                     /locus_tag="LP468_002697"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBL2082163.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1322..1780
                     /locus_tag="LP468_002698"
     CDS             1322..1780
                     /locus_tag="LP468_002698"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL2082164.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1939..2409
                     /locus_tag="LP468_002699"
     CDS             1939..2409
                     /locus_tag="LP468_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL2082165.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2462..2577)
                     /gene="rrf"
                     /locus_tag="LP468_002700"
     rRNA            complement(2462..2577)
                     /gene="rrf"
                     /locus_tag="LP468_002700"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          862 a          505 c          497 g          771 t
ORIGIN      
        1 gaaacatgca cattcaaaca aaattgatcc acggaggcat cagtgaagat cccacaacag
       61 gagctgtcag tgtacctatt tatcaaacat ccacttatcg gcaagatggc gtcggccagc
      121 ctaaacaata tgaatattca agatctggta atcctactcg ttttgcattg gaagaactga
      181 ttgctgattt ggaaggcggt gttcgaggat tcgctttttc ttctggtctt tctgggattc
      241 atgccgtttt ttctcttttt caagctggcg atcatatctt attaggagat gatgtctatg
      301 gaggaacatt ccgtctattt gacaaagttc ttactaaaaa tggtctcgag tacacgatca
      361 tagatacgag taatcttgat aaaatagaac aatccatcaa acccaataca aaagcacttt
      421 atcttgaaac acctagcaat ccgcttctaa agattactga tttagaaaaa agtgccactc
      481 tggctcatca acatggattg atagttattg ctgacaatac atttgctact ccttattttc
      541 aaagaccttt agatctcggt tctgatatcg ttgtccatag cggtaccaaa tatctaggcg
      601 gacacagcga tgtagtagct ggtttagtga cttctaacca taaagatcta gccgatcaga
      661 tcggatttta ccaaaatgct atcggagccg tacttggtcc ccaagatagc tggttacttc
      721 agcgcggaat caagacacta agtgttcgta tggaggaaca tcaaaaaaat gcttttgtgg
      781 tagctgattt tctattttct catccagcag tagaaaaggt ctactatcca ggattacccg
      841 atcatgaact ccatggagtt gctaagcagc agatgagcgg ctttagcgga atgatttctt
      901 ttactttaaa aaatgaagaa tctgctattc catttgttga atcactccaa ctatttactt
      961 tagcagaaag tttaggtggc gtagaaagtt tagtggaaat tccttctgtc atgactcatg
     1021 cgtctattcc aaaagaaaaa cgagaagagg ctggcataaa ggacggcttg atccgtcttt
     1081 ctgtaggaat tgagtatggt caggatctca taaacgattt agctcaggca tttgacagaa
     1141 tcaagaacta gaagtcccaa taaacgactt agcagaaaaa tctaaaaaat atttcagatt
     1201 gctacacctt ggaaacgata agtgttagaa tcaagtagaa agacgttttt gtaaatttca
     1261 ctaaataatt ctttagtgaa aagcatcaaa acgaatgaac aaacagatag gagtcttaca
     1321 aatgagaatg aatgtcgaaa gttttaatct tgaccataca aaagtcaaag caccttatgt
     1381 acgtgtagct gatcgaaaaa cgggtgcgca tggcgatgtc atcattaaat acgacgtccg
     1441 ctttaaacaa ccaaataaag aacacatgga catgccaagt ctacattcac ttgagcactt
     1501 gactgccgaa ctaatccgca atcacgcaga ttacatcgta gactggtctc caatgggatg
     1561 ccaaacaggc ttttacttga ctgtattgaa tcatgaaagc tacgaagaca ttttagatgt
     1621 tcttgaagca acaatgaaag atgttcttga agctactgaa gtacctgcaa gcaatgaaac
     1681 acaatgtggc tgggctgcca gccatacact agaaggtgca caagctttgg ctcgtgaatt
     1741 tttagcaaaa cgcgatgaat ggtctgaagt agaagcatag tttctaaaag aacgtaaaga
     1801 tgagaagcaa tatagctatc ttatcttcgt attttattaa atatttattg tctgaaaaga
     1861 gttctaaacg ggaaaacaaa tagctagttt tcagtttagc gctcttttta ttatataaaa
     1921 tagaaaggag aaaactttat gtctatttat aattttgaaa ctactttaga agacggcact
     1981 gtctattcat tgaaaaaata tgcaggcaaa ccgataatca ttgttaacac tgcaacaaaa
     2041 tgcggtctag cacctcaatt taaacaatta gaagaacttt accaagctta tcagacacaa
     2101 ggtctggtta tcttaggctt tccttccaat caatttaaac aagagctaga ttcagcgact
     2161 gaagcagcag aagcttgtaa aaccacttat ggcgttacct tccctatgca tcaattgatt
     2221 gacgtaaatg gagaaaatac agatcctctt tttacttatc ttaaaaatga agctcctggt
     2281 actgtcacta aagcaataaa atggaatttt actaaatttt tgattgatag aaatggcaaa
     2341 gtaatcgaac gatttgcacc acaaacttct ccattgaaaa tgaccgctgc aattgaatcc
     2401 gttctttaac ttaataaaaa taaaaaaaga tgaactattt ctagttcatc tttttgcctt
     2461 tgcgtggcga cgtcctactc tcacaagggg caccccctca ctacaatcgg cgctaagaag
     2521 cttaacttct gtgttcggca tggttacagg tgtatccttc tcgctatcgc caccacactg
     2581 tggtgttatc ttttattgag taaattttgt tcactcaaaa ctggatttga agtca
//
LOCUS       DAFEML010000136         2557 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFEML010000136
VERSION     DAFEML010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.142"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(104..1092)
                     /locus_tag="LP468_002701"
                     /pseudo
     CDS             complement(104..1092)
                     /locus_tag="LP468_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1170..2210
                     /locus_tag="LP468_002702"
     CDS             1170..2210
                     /locus_tag="LP468_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HBL2082166.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELGQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTFKKADSKKQQVFLE
                     ETFPSLKKKLLNSDIDHLLFEDETMIRDYQAIGCTWFLRGHQRKIPTYGQHKGVKLIG
                     TLDYEAGRIICTEEGAYDAAAFLRFLERTLREYPTGKIVMVLDNALIHHAKLIQSFLE
                     ENARRLALIFLPPYSPQLNLMEGVWKWLKESVINNVFFDHVQKIKQSVRGFLADVNER
                     PLEVIDRLCVRM"
     gene            2230..2557
                     /locus_tag="LP468_002703"
                     /pseudo
     CDS             2230..2557
                     /locus_tag="LP468_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          758 a          519 c          523 g          757 t
ORIGIN      
        1 ttcttgctcg aaagttatgg aaatttcgat agccgtaggc tacttgtatt gtgcaatagt
       61 tttttacaaa aaaaaggggt gcggatattt tttttggacc tttttaacaa atatatcttt
      121 gcttcttccg atattgaaga gggcttagcc ctcctaaaga taacttaatt cgttgattat
      181 tataccaatg aatataatta tccaatttgt ttataaactg attgattgtt gtattattcc
      241 agtcacgttg ataaaacatc tcgtttttta atcgtccaaa gaaaccttcg cacgctgaat
      301 tatctggcga ataacccttt ttagacatag agtgaagcaa gttgtctttg ttccaatagt
      361 ccaactaaca atagcaccat cgtaacaatc gacaagtggt gataagtaga ttttccctgc
      421 gggaattcta aattcagtaa tatctgttaa ccatttttca tttggcttct ttgctttaaa
      481 attccgattt aataaattgg ggtgtgcagg agaaatttcc ccagcatacg aagaatactt
      541 ttttcgtcta gaaaatttaa caaatagatt ttcctcagtc atcaatctac gtacaacttt
      601 ttcagaaagc tttttaccca tattttttaa agcttggtga attctacggt aaccatacgc
      661 acagaagtta tgattgaaaa tcgtgataat taattgacgt tctttgtaat acttatctgg
      721 tttctcaagt gcttgttttt gataaaaata gctgctttta ggcaactgga gctgttgaag
      781 aagctctttc aaggtgaact gatttcgtaa ggcatcaatc aatatcgttt tttcttgatt
      841 tgatagacaa agaagattga cgcctttttc tttttttagc agttcagccg ctccttcgag
      901 taatgctttt tcgagctgta attggtgtac ttgtttttgt aagtcttcta cttcctttaa
      961 aagtagctct ttttgttttt cctgattttt taaagtcata cgcaatggaa aatcctttcc
     1021 aagaaccgtg tttttccatt gatatagagt aactctacta attccttcag attcggctaa
     1081 atttttccta ttatataaat tgagttaaat tgtattcgtt tttcctccta taggcgtata
     1141 ctaaagaaaa cacttgagga gtggggaaca tggagacaga acgccaaatc cgtgaattgg
     1201 aaaaagcgat gaatacgaca gacaaccgcc ggttgtacga gcgtttcctg gcagtcaagt
     1261 tggttcttga aggccacacc cggaaagaag ccgggcacac catcggccgc gacgagcata
     1321 ctgtcagcca ctatgtgaaa aactactgcc ataatggaat ccaaggttta gtctccaaaa
     1381 aacaaagcgg acgaccttca cggctgacag atgaacagga agcggaactg ggccaaatcg
     1441 tcgcctacca cactccggag gaagtaggtt tcaaatcccg tgccaattgg acattggcga
     1501 ttgtgtgtga cctgattctc cgggaatgga gttatggata tacgcaaaaa ggcgtggcgg
     1561 acctccttca ccggctagga ctaagctgga cccgtccgac gtataccttc aaaaaagcgg
     1621 attccaagaa acaacaggta tttttggaag aaaccttccc gagcctaaaa aaaaaattgc
     1681 tgaatagcga tattgaccac ctcctattcg aggacgaaac catgatccgg gattaccaag
     1741 ccattggctg cacctggttt ctccgcggcc accagcgaaa aatccccact tatggacaac
     1801 acaaaggggt aaaattgata ggcaccttgg attatgaagc cggtcggatc atttgtacag
     1861 aagaaggggc atacgacgca gcggccttcc tccgttttct ggagcggacg ttgcgggaat
     1921 accccaccgg aaaaatcgtg atggtattgg ataatgccct tatccaccac gccaagctga
     1981 tccagtcttt tcttgaagaa aacgctaggc gcctggcact catcttcctc cctccctaca
     2041 gccctcagtt gaacctaatg gaaggcgttt ggaagtggct caaggaatcg gtcatcaaca
     2101 atgttttttt tgaccacgtc cagaaaatca aacagtcggt ccgcggtttc ttagccgatg
     2161 taaacgagcg tccccttgag gtgattgacc gactgtgcgt gcggatgtaa agtatttaat
     2221 tcaacctata tagatgcaca gtttttagat tttaatactg gaaatgaact cctagatact
     2281 gctatgttcg atatgttttt atcattgcta agttatattg cacaaaacga acgtgagaaa
     2341 atccgtgaac gtcagcggca aggagtatta ttggccaaaa aagctggtcg atataagggg
     2401 cgaccaattg aatattctga gaactcaaca gatccgcaaa aacgattagt ctttaaaact
     2461 gtggtggaca tgttaaatca aggagttcca gttgcagaaa ttgccaaaga aaatggtctc
     2521 tctcgaccaa ccatatataa aataaagaaa gcgaatg
//
LOCUS       DAFEML010000137         2442 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFEML010000137
VERSION     DAFEML010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.143"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..224)
                     /locus_tag="LP468_002704"
     CDS             complement(<1..224)
                     /locus_tag="LP468_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2082167.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWK"
     gene            282..389
                     /locus_tag="LP468_002705"
                     /pseudo
     CDS             282..389
                     /locus_tag="LP468_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            603..1298
                     /gene="vanR"
                     /locus_tag="LP468_002706"
     CDS             603..1298
                     /gene="vanR"
                     /locus_tag="LP468_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2082168.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1276..2430
                     /locus_tag="LP468_002707"
     CDS             1276..2430
                     /locus_tag="LP468_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL2082169.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          813 a          456 c          497 g          676 t
ORIGIN      
        1 attttccatg aataaaagga ttttttattt ttctttttcc aaatttgata gagtagtttg
       61 ccatattctt gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc acgatcatat
      121 aagatttctt gaacttcacg atagctaagg ttataacgaa gatagtagcc cacggctaca
      181 ataatcacat cctgctgaaa ttgctttcct ttaaaatgat tcatcgtcat tcctcctgct
      241 atctttttct attattctac cttatttgat agtagattta aaactttgca acagaaccag
      301 aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg gcttcattat
      361 acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg ggcaatattt
      421 ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc gaaaagccct
      481 ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg taaatgctta
      541 taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa agggtgataa
      601 ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat ttggttgaat
      661 tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa gaagcattgg
      721 aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt cccggcacaa
      781 gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt atcatgctga
      841 ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg gatgattata
      901 taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat
      961 acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac tccggccttg
     1021 tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc cttactccca
     1081 ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt agctccgagc
     1141 tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac accatcaccg
     1201 tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg aaatatataa
     1261 aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta ttccaaacta
     1321 gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt attcgtgttg
     1381 tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac
     1441 aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat
     1501 atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg
     1561 ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag
     1621 aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac
     1681 acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa
     1741 aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt
     1801 tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg
     1861 catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt
     1921 acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg
     1981 ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt
     2041 attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt
     2101 aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc
     2161 gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa
     2221 gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat
     2281 acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg
     2341 cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct tccagcgatg
     2401 ccagacttgg ttgataaaag gaggtcctaa gagatgtata ta
//
LOCUS       DAFEML010000138         2397 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFEML010000138
VERSION     DAFEML010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.144"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            206..2068
                     /locus_tag="LP468_002708"
     CDS             206..2068
                     /locus_tag="LP468_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2082170.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2397
                     /locus_tag="LP468_002709"
     CDS             2068..>2397
                     /locus_tag="LP468_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2082171.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          714 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataat
//
LOCUS       DAFEML010000139         2356 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFEML010000139
VERSION     DAFEML010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.145"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..669)
                     /locus_tag="LP468_002710"
     CDS             complement(<1..669)
                     /locus_tag="LP468_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1062 family transposase"
                     /protein_id="HBL2082172.1"
                     /translation="MTYTHLTSNKLAMIEAYYNNHQSVAKTAVLLNRSRQTIHKVYQF
                     FKTGHNALDYFNQYKKNKTRCGRRPIVLSDKQTEYIQKRVVQGWTPDVIVGRAEFSIS
                     CSMRTLYRMFKQGVFEVTHLPMKGKRKANGHKETRGKQSFRRSLRDRGNDYSKFNQEF
                     GHLEGDTIVGKKHKSAVITLVERLSKVIITLQPEGRRAIDIENRLNQWMQSVPKHLFK
                     SMTFR"
     gene            complement(751..2205)
                     /locus_tag="LP468_002711"
     CDS             complement(751..2205)
                     /locus_tag="LP468_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2082173.1"
                     /translation="MFSKEESSMGYKELGKDILANVGGSENVSSLAHCATRLRFNLKD
                     DSKADESAIRNLKGVVGVVNQGGQFQVIIGGDVKFVFAEIDKLGDFSASKESSSEANN
                     KGIVSKVLDTIAGIFVPIVPALTGAGMLKALLALLVMLEWMTPESQTYQFLNFIGDAA
                     FYFLPVLLASSAAKKFGCNQYIAITLGAILLHPTFTAMIAGARETGESLALFGLPVTL
                     ANYGSSVIPIILAIWFMSYIEPIIDKLMPNAVRIFMTPLLTLLIVAPITLIVIGPLGT
                     FLGNGLGSLIEFVNTYASWLVPLLVGAFTPLLVMTGMHYGLIPIGINMLATSGFDTVA
                     GPGMMVSNIAQGGAALAVAFRTKQLSVKQLAVSSGLSAFMGITEPALYGINMRFKKPL
                     IASMVGGGAAGLFIGIMGVGRYAQVAPGILALPSFFGEKGLSNFIYAAIGCAIAFVVG
                     FIASFILGIDEETEEVKEDTSEIPVNIASDNRRL"
BASE COUNT          763 a          486 c          372 g          735 t
ORIGIN      
        1 gcgaaaagtc attgatttga atagatgctt aggtactgat tgcatccatt ggttcaaacg
       61 attttcaata tctatagctc gtctgccttc tggctgaaga gtgatgatta ctttagataa
      121 tcgctcaacg agggtaatga cagcactttt gtgcttttta cccacaatag tatccccttc
      181 aaggtggcca aattcttgat tgaatttaga ataatcattt cctctgtcac gaagtgatcg
      241 acgaaaagat tgttttcccc gagtttcttt gtgtccgttg gctttacgtt ttcctttcat
      301 aggtaggtga gtcacttcaa atacgccttg tttaaacata cgataaagtg tacgcataga
      361 acaagaaata gaaaactctg cacggccaac aatcacatca ggtgtccaac cttgaacaac
      421 cctcttttga atatattctg tttgtttatc tgataagaca ataggacgtc tgccacagcg
      481 agttttattc ttcttgtatt gattgaaata atctagagca ttgtgccctg ttttgaaaaa
      541 ttggtaaact ttatgaatcg tttgtctaga tctattcaat agtactgcgg ttttggctac
      601 agattgatga ttattataat acgcctctat cattgcaagt ttatttgatg taagatgggt
      661 ataggtcatt tgtcttcact ccttataatt cttttgcggg aactatcttg agtgtagcat
      721 aaatgacttt tttatttgtc tagcttaatt ttacaatcgg cgattgtcac ttgcaatatt
      781 tactggaatt tcgctcgtat cttcttttac ttcctcagtc tcttcatcaa tacctaaaat
      841 gaatgaagca ataaaaccga caacaaatgc aatcgcacaa ccaatcgctg cgtaaataaa
      901 atttgatagt cctttttccc caaagaaact tggtaacgca agaatgccag gagcaacttg
      961 agcatatcga ccgacaccca tgattccaat aaatagtccc gctgctccac cacctaccat
     1021 tgaagcaatt aacggctttt tgaatcgcat attaattccg tataaagctg gttcagtaat
     1081 tcccataaaa gcagacagac ctgaagaaac agctaattgt ttgacagaaa gttgttttgt
     1141 tctaaaggca actgctaagg cagcaccacc ctgagcaata ttggaaacca tcatacctgg
     1201 accagcaaca gtatcaaatc cagatgttgc taacatatta ataccgattg gaattaaacc
     1261 gtaatgcata cctgtcatca caagtaatgg agtaaatgca cccacaagta atggaaccaa
     1321 ccaacttgca tacgtattaa caaattcaat aagtgaccct aacccattac ctaagaatgt
     1381 acccaaagga ccaatcacaa ttaaggtaat tggtgcaaca atcaacaatg ttaacagagg
     1441 cgtcataaat attcgaacag cattgggcat caatttatcg ataatcggct cgatatatga
     1501 cataaaccaa atagctaaaa taatcggaat aacagaagaa ccatagttag ctaacgtcac
     1561 aggtaatccg aataaagcta aggactcacc tgtttctcta gcacccgcaa tcattgctgt
     1621 aaaagtcgga tgtaacaaaa ttgctcctaa ggtaattgca atgtactgat tacatccgaa
     1681 tttttttgca gcagaactag ctaataagac cggtaaaaaa taaaaggctg catcaccaat
     1741 gaaatttaaa aattgatagg tttgcgattc tggtgtcatc cattccaaca tgactaatag
     1801 agctaataat gcttttaaca tccctgcacc tgttaatgcc ggaacaattg gaacaaaaat
     1861 acccgcaatt gtatctaaaa cttttgatac aatcccttta ttgtttgctt ctgaactact
     1921 ttctttagaa gcggaaaaat ctcctagttt atcgatttcg gcaaatacaa attttacatc
     1981 tccaccaata atgacttgaa attgaccacc ctgattaact acacctacaa cacctttaag
     2041 atttctaata gctgattcat ctgctttact gtcatctttt aaattaaatc gaagtcgtgt
     2101 tgcacaatgc gctaaactgc ttacattttc agaaccacca acatttgcta atatgtcttt
     2161 tcctaattct ttatacccca tgctactttc ctccttagag aacattttct cttttgataa
     2221 tttgaatata gcgtgctatt aatagataaa caatacattt gaaaccgttt tacacagcgt
     2281 tgcgaaattc attcagttta cgattatttt ttcgcaacac tgttccaaaa aaataaaatc
     2341 cacttactaa ctaatc
//
LOCUS       DAFEML010000140         2269 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFEML010000140
VERSION     DAFEML010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.146"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            190..444
                     /locus_tag="LP468_002712"
     CDS             190..444
                     /locus_tag="LP468_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2082174.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            445..762
                     /locus_tag="LP468_002713"
     CDS             445..762
                     /locus_tag="LP468_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2082175.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1321..2256
                     /locus_tag="LP468_002714"
     CDS             1321..2256
                     /locus_tag="LP468_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082176.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          428 g          711 t
ORIGIN      
        1 atgttaacgg aagtgtatgg tgagtagttc actcgtattt tgatatcgtt tgtatatgtt
       61 ttcagcgttc taagtggctt attttgtcca ataataatat ggagtggaat cccttaagaa
      121 acaccgttgg caattgttgt tataacatgt tataatttat tcatcaaaaa ctaaaaggag
      181 tgtgataaca tgggaaaaga actaaaggtt agaaagatcg gcaatagcgt gggagtgatc
      241 cttccaagct ctcttggatt aaaaagcgga gacattatcc aagccaaaca agaaggcaac
      301 ttattcatat tagatactac tcaaatagca aaagaacacg atcgcaaatt gattgaagaa
      361 agtttccaag actttgagaa aggtttaaca gtttcagaaa ttgaaatggt aaaagctttc
      421 ggaaaatacg gctggagtga atagatgaaa gagtacacgc tagtttattc taaaagtttt
      481 cagaccagcc ttgaaacgat aatagaagaa tgggaaaatg agcttgctct ttctccagcc
      541 agcataaaaa gatttgtagg tgcgatccag aaggctttag aactaaccaa aaattttcca
      601 actatgcatg aggaagtttc cgaaatctat ggaatggata tcccaacata tcggatcgtg
      661 atcggcaaaa gctatgcctt attttatcgg atcgaccatg aaaaaaaaga gatacttgta
      721 ggacgtattt tccaatctaa acaaatgaaa ctaggctttt aacaataatt aggaaaaagt
      781 cgctcatcct ctacaggtgg gtgattaatg ccgctcgata tggttgttaa ccgtcggtta
      841 ctcgaagatt gatatataag acttagtacc tttttatttt gctccatgtt atggccgaag
      901 gtctaaagat acaatcatta gtctagagaa aaattaagaa ccgtaggaac tacggggatc
      961 gcttggtgaa taagagacac tgctattagt gaaaaaataa gatatcaagt acgctctatt
     1021 cccaaaaatt tcgtgacttt actcatgaga ggttcaagta gtatattttt aatcaaaatt
     1081 gacgtaactt ttaataaata ctacctaaat aaggtagtat ttatttttgt gttttaaaag
     1141 aggaagtcca atatatctat gggaaacttc ttaaatatta tgttggtaca tgaaaatata
     1201 catccctgct agactattta caacatttta ctttgtacgt attcttgttt taaaaggaat
     1261 gggataaaat ataggtacaa taactatttg atgctaaata taattaatgg aggagagata
     1321 gtgaacatac ttaatgaaaa aagatatgta tggtttgctg gtaaaaaata tattactact
     1381 ttcaaaagat tatccgagtt aatgcagcag actgttaaaa gtgctatgcc tgaaggatac
     1441 aagtttaatt ttgttcaatc ttcagtatct actgaaagta tctatttttc aattctttct
     1501 gagagtaggc tttttcattt tagaataagt tctcatgtaa agaaaactga tgttgatata
     1561 tatacgttcc gtacaaataa ttataaaaat ttaaatgatt tgagtagaag tatcagtgaa
     1621 tatctcaagg ggaatagcta tctcaagatt cgattttcac atatattaat tttactacca
     1681 tatttgaatg agaatttcac cctaattcaa gtagataagt ctttcattgc ctcaggtaat
     1741 caaggaaata tgaatattac aagtaacaaa acgtcacgtg tgctattggc gttgatgggt
     1801 tacggaattc tttatagaga tgaccaaaat ggccagattc taataaatcg ggctgggcgt
     1861 tcattattaa tgaaatatag aaaatttata ccggaagatt ttcaaaactt acagttagaa
     1921 aacatgcgtt tagaagattt atttagatta gcagaagatg ataagtatag atttgaagtt
     1981 ttgaaaattc aaaagaatga actattgaat aagttatatc ctgagaatgc gataaaagca
     2041 cattttggtg atgctaatca tatgtatagt tggttcattc ctaaaagatt tagagggaaa
     2101 atcaatgctg gagatcaagt gaaagtactc aatcgaaata gtacagatgt cgtaatgata
     2161 acagatatct atgtagaaga tgaagatata atcaaatata tgaagcctgt gataaaactt
     2221 gttaataaaa ataaaggaac ccgtggtgct agttaatttt ttcctagag
//
LOCUS       DAFEML010000141         2232 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFEML010000141
VERSION     DAFEML010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.147"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP468_002715"
     CDS             complement(45..1364)
                     /locus_tag="LP468_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2082177.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP468_002716"
     CDS             complement(1361..2014)
                     /locus_tag="LP468_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2082178.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          735 a          341 c          185 g          971 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aa
//
LOCUS       DAFEML010000142         2216 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFEML010000142
VERSION     DAFEML010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.149"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..134
                     /locus_tag="LP468_002717"
     CDS             <1..134
                     /locus_tag="LP468_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2082179.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            131..1009
                     /locus_tag="LP468_002718"
     CDS             131..1009
                     /locus_tag="LP468_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082180.1"
                     /translation="MTNHKRKNCVIPLAISMSLLIYTHVLSTFMSVIVIGFLFIGSLF
                     SKRKEKKEMSDLILNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTNLQERALNI
                     SDSLIGAVNNDLVTFTMGTIGVVSLILPLFFLKKFTNKEKIIYFCAVTTWFLSTNLFP
                     WEILQKTPIQIIQFPWRILGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTV
                     TAATEANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVK
                     VGDRWRMHLIKHIIPK"
BASE COUNT          803 a          298 c          338 g          777 t
ORIGIN      
        1 aagtcaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc ataaaagaaa gaactgtgtg attcctttag ctatcagtat
      181 gagtttgcta atctataccc atgttctctc cacttttatg agtgtgattg ttattggctt
      241 cttgtttatc ggctctcttt tctctaagcg aaaagagaaa aaagaaatgt cggatctgat
      301 attaaatatg ataaaagctg ttggttggac cattctttta acggcttacg tttggtatcc
      361 gatgttacaa caagtcctac atcaaaaaat taatcgtcct tttcgcacaa atcttcaaga
      421 aagggcattg aatatttctg atagtttaat cggtgcagta aataatgatt tagtcacgtt
      481 tacaatggga acaattggtg tggtttcatt gattcttcca cttttctttt taaaaaaatt
      541 taccaataaa gaaaagatta tttatttttg tgcagtgacc acttggtttt tatcaacgaa
      601 tctttttcca tgggaaattt tacaaaaaac acctattcaa atcattcaat ttccgtggag
      661 aatcttgggt tttcaagtgc tttttggttc attaatctta accatagtgt ttttaaagtg
      721 gaaaacaagc aacaaaaaaa gtatgtggag ccttgtagga atagttctta ttatttttac
      781 tgtgactgca gcaacagaag caaattattc gcataaaatt cagtcgtata aaggtcgttt
      841 agttatgacc aaaaaagatg ttacacgtta tacatcctca agaactggag gcctatatga
      901 ctatgcacca ttagatgcat tgaaatataa agatcattta aagaaacatg aagtaaaagt
      961 tggtgatcga tggagaatgc atctcataaa gcatataatt ccaaaatagt ctatacagta
     1021 gaagatgccg atgagcaaaa tatcacatta cctgtattca attattgggg aacagttgtg
     1081 aaagtaaatg ggaaaaagag cactatagaa aatgacaatg gtttagtgtc tattaaaggt
     1141 acgggaaaaa gaactatagt tgaggtttca tctacgtatc caactacgat gattctatct
     1201 ttattaatta gttcaataac ttttatattc ttatttacac gttatttaat aagatgctgc
     1261 ggttaaatga aaatagatta gatagatatt ataaatatgt tgattctatt ttcatagcaa
     1321 tggagaaaat acattagcaa tatataaaag aaggtatcaa gagtcacagt gaatttattc
     1381 cgaaaagtga aaagagcaaa tataaaattt aataaaaata tagaactaaa taggaaaacg
     1441 tagacgtaat tttctacgtt ttccttttca tatatattaa atattacgga aaattatata
     1501 aactaattta gtgttttgtt tgtaattcct aattttgctc cacttttaga taatttttag
     1561 gtctatttaa ctcatcagac attctatgct catttttctc caaatttgtt tcaactcttt
     1621 cgtacttaat tttgcgtatt tgaaaattct tcttttagag tacttttatt acgatactag
     1681 tatgatatat atctatagca aacagttaaa atcttcctaa aataagcgaa tagcattcct
     1741 aaaacctata aaatttttag atgaagcgac aagtggacaa ttaataaact acttgaacat
     1801 gaaattatgg atcacctttc aaatttagaa aatggaattc ttatacttat tgcgcaacat
     1861 ttattgattg caaaattatg tgacaaaaag aactagtaga agaaggaatg atggcttgat
     1921 aataaagtac tacctattaa aggtagtact ttatttaatt tagtataaat taacatacta
     1981 ctatatttta ggtttcatat tatataaatt aataatatac taccatttat tggtagtata
     2041 atttaaaggt aataagttat tcttttatta ctatgtttgg gttttatagc aaggaaagtt
     2101 taataagagt ttggacctag caaacaatat taatgaggtc attaaatctt attatcttta
     2161 gtgatataac gaaatatcta cacagacaaa attatgatct tgcgtaaagt tataaa
//
LOCUS       DAFEML010000143         2195 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFEML010000143
VERSION     DAFEML010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.150"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            199..1623
                     /gene="istA"
                     /locus_tag="LP468_002719"
     CDS             199..1623
                     /gene="istA"
                     /locus_tag="LP468_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL2082181.1"
                     /translation="MLTMTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLL
                     PQPKARKKTGMMYTEKWGGIVSLWLSEDAKLPKKKRRTAEAMTTALKADGFPGSYRTV
                     CVFIQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPF
                     SNAGFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVTQTKTKTEQAVLTD
                     GFLRFSMHYGFETQVCNPRSGNEKGSMENKVGYVRYNFFSSTPIMKDFASFNEALAVE
                     LSHDRERIHYEKHVIINDLWNTEKTDLLALPDTDYPVFKEIEVKVNKYNEIKLDNERI
                     HVPRVRNYSIIYGLLRFDSYQLISTDGEIISEGLRPYMMKKRAIDWQAILPDWRRKSR
                     AMHYSRYWKYLPERIKLFLSHPDWKEQEKRLNQISGLLVTHDMLGIDTHFYDMFSAST
                     TTDAYDIDWHQYDAFLSLTGEVID"
     gene            1623..>2195
                     /locus_tag="LP468_002720"
     CDS             1623..>2195
                     /locus_tag="LP468_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2082182.1"
                     /translation="MDQAKSLETACKLLRLSHVLPTLVRKDLDYSFETKEDWLMYLLE
                     KELACREELKTARLLKQAKFPNKRTLEDYEWHDHICLPNATTKDELLSLSFIHQKENA
                     VFVGTPGTGKTHLACGLGQLAAKSGIDTRFWRVSDLVNELEHHWKNNTLEVFKHRFDK
                     VKLIILDEMGYVPFTKEGAELLFQLISDWYE"
BASE COUNT          701 a          420 c          478 g          596 t
ORIGIN      
        1 gagtcatcta tttcgtttat tcactttttc aagtggacat tcattaagct gtttatggca
       61 gaataaaagt acatacaagt gcaacgaaaa actacacaac tccgcaaatc gattaagtta
      121 agataaaaag ccattgcggg caacctgaaa ttcctctaaa gttatagtct cgacactgta
      181 actggaggta agaaaggtat gctcacaatg accgatatta atactatcag aaatttacga
      241 aataatcatg ataaatccat taatcatatt gcaaaggagc tagatgtaaa ttggcgcacg
      301 gctaaaaaat atgcagatga tgatttgctg ccgcaaccta aagcacgcaa aaagactggt
      361 atgatgtata cagaaaagtg gggaggcatc gtttccctat ggctttcaga agatgctaag
      421 ctgccaaaga aaaagcgtag gactgctgaa gcaatgacta ctgctttaaa agccgatggc
      481 tttccaggat cctaccgaac agtctgtgta ttcattcaag attggaaagc gacacactac
      541 ttggaaacac tggaagacca aggctttgag cgtcttgaac acccgccagc agaagcgcaa
      601 cttgattttg gtacgatgga agtttgtcac gatggagcgt ttaaagatgt gaaggtatta
      661 gtgatgactt tcccttttag taatgcagga ttcgccgttg tactccccgc cgagaatcaa
      721 gaatgtttgt tggaaggcat gaaagaactc ttcagccaat caggtggcgt tcctcggaaa
      781 atacggattg ataatatgtc aacggccgtt actcagacaa aaacaaagac tgaacaagcg
      841 gtgctgactg acggtttcct ccgattttct atgcactatg gttttgagac acaggtgtgc
      901 aatccacgta gcggaaacga gaaaggtagt atggaaaaca aagtcggcta tgtacggtac
      961 aacttctttt catctacacc gattatgaag gatttcgcca gtttcaacga ggcattagcg
     1021 gtggagctgt cacacgatcg agagcgaatc cattacgaaa aacatgtcat tatcaatgat
     1081 ctatggaaca cagaaaaaac agatttgcta gctttgccgg acaccgatta cccagtattt
     1141 aaagaaatcg aagtcaaagt caataagtac aacgaaatta aattagataa cgaacggatc
     1201 cacgttccac gtgtacgcaa ttattcaatt atttatgggc tgcttcgttt tgattcctat
     1261 cagctaatca gcactgatgg tgagattatt tcagaaggac ttcgtcctta tatgatgaaa
     1321 aaacgagcaa tcgattggca agcaattctt cctgattggc gcagaaaatc gcgtgccatg
     1381 cattactctc gctattggaa gtatttgccc gaacgaatca agttatttct cagtcatcca
     1441 gattggaaag aacaggagaa gcgtttaaat caaatctcag gtttattggt gacacatgat
     1501 atgttaggga ttgatacaca tttttacgac atgtttagtg cctcgactac taccgatgcg
     1561 tatgatattg attggcacca atacgatgct ttcttgtctc taacagggga ggtcattgac
     1621 tagtggatca agcaaaaagt ttagaaactg cctgtaagtt gctgagactt tcccatgttc
     1681 ttcccacttt ggttcgcaaa gacttagatt acagctttga aaccaaagaa gattggttga
     1741 tgtatcttct ggaaaaggag ttggcttgcc gtgaagaatt gaaaactgcc cgactcctaa
     1801 aacaagcaaa gttcccaaat aaacgtacct tagaggatta cgaatggcat gatcatatat
     1861 gtttgccaaa tgcgacgact aaagatgaat tattgagtct atcgtttatt catcagaaag
     1921 aaaatgctgt atttgtgggt acacccggta ccggtaaaac acatctagct tgtggattgg
     1981 gtcagctggc agccaaatca ggtatcgata cacgcttttg gcgggtatca gatttagtca
     2041 acgaattgga acaccattgg aaaaacaata ccttagaggt cttcaagcat cgcttcgata
     2101 aagtaaaatt aatcattctt gatgagatgg gttatgtgcc tttcactaaa gaaggcgcgg
     2161 aactgctttt ccaattgatc agcgattggt atgaa
//
LOCUS       DAFEML010000144         1994 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFEML010000144
VERSION     DAFEML010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.151"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            88..387
                     /locus_tag="LP468_002721"
     CDS             88..387
                     /locus_tag="LP468_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082183.1"
                     /translation="MNGQTPQTPQTPVVEESTQQSQQTETTTEQVKLYGEVLTDPHEK
                     AEMIRDLYEGNQGFNRDILNSIPDQEIIDSFVGNATNAQLAQSTTNLLEKYPNLK"
     gene            989..1594
                     /locus_tag="LP468_002722"
     CDS             989..1594
                     /locus_tag="LP468_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBL2082184.1"
                     /translation="MVLENKLGITNQIALAKAEERISKQKAKHLYDSGKINEIEVGTF
                     KGLATIHFYLFSDIYKFAGEIRTVNLAKGNFRFAPLMYLETSLQYIDKMPQSTYKEII
                     EKYVEMNIAHPFREGNGRSMRIWLDLMLKKELQKVIDWNLVDKEDYLSAMERSPINDL
                     EISHLLSQALTEQIHDRQLFMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          789 a          242 c          338 g          625 t
ORIGIN      
        1 acgcaaaaaa atcagggtaa tgaaaataat tatctgtact ttaacgaaac tcaaaatcaa
       61 cagttaaaac aaggtttcat tgatattgtg aatggtcaaa ctcctcaaac tcctcaaact
      121 ccagtagtag aagaatctac tcaacagtct caacaaacag aaaccactac tgaacaagta
      181 aaattatatg gagaagttct tactgatcca catgaaaagg cagaaatgat tagagaccta
      241 tatgagggta atcaaggatt taatagagat attttgaatt caattccaga tcaagaaatc
      301 attgattcat ttgtaggtaa tgctacgaat gcacaacttg cacaaagtac aacgaatcta
      361 ttagaaaaat accctaattt gaaataagag ttacaaatgg acgaggcttt taggatgatt
      421 catcattcta acatggttca ataattagag ttatacatca tcaagtaata actgattctt
      481 aaaaagcacc ataagctttt taagaatcag ttttatctat aaagagggag aaagaatgta
      541 ttaaatgact ttttaactaa tatacataaa aacaataata ggaatgagaa ttgaaagagc
      601 acaagcattc ttttgaatga gatatttaat tgaaaaccaa tacagtacta gaagtaccca
      661 aagtgaccaa aagatagttg ataaaaaatg agtaagaaaa gtaaaatgag ataaaaaatt
      721 gtcactttag gtactttggt actaagaaag gcttgttttt gtctatttgt ttcactaaag
      781 tatataaaac agaattaatg caggaatcat agaaagtttg tcatactttc tatgattccc
      841 tgttttactt gactttttga tataatagaa tagttaagaa agtattcaag agaatatttt
      901 agaaaataga gtttatgagt ttatgcactg tagaaagaat ttgagcgtca atgatttagt
      961 gatttaatat atgaatgagg tgattctctt ggtattggaa aataaattag gaataaccaa
     1021 tcaaatagct cttgcgaagg cagaggaacg aataagtaaa caaaaagcaa aacatttata
     1081 tgatagtgga aaaataaatg aaatagaggt tggaacattt aagggcttag caacgattca
     1141 tttttatttg ttttcagata tttataaatt tgcaggagaa attcgaacag tgaatttagc
     1201 gaaggggaat tttcgttttg ccccattaat gtacttagaa acttctttac agtatattga
     1261 taaaatgcct caaagtacgt acaaagaaat tattgagaaa tatgttgaaa tgaatattgc
     1321 ccatcctttt cgagaaggaa atgggcgaag tatgcggatt tggttggatc ttatgttaaa
     1381 gaaagaacta caaaaggtaa ttgattggaa tttagtagat aaggaagact atttatctgc
     1441 tatggaacgt agtccaatca acgatttaga aattagtcat ttactttctc aagcactaac
     1501 agaacaaatc catgatcgtc aactatttat gaaaggaatt gatgtaagtt atttttatga
     1561 ggggtattca gagtatacga ttgatgatct ataaatctgt ttaggtttaa tgtatttcta
     1621 cacaattatt cttacaataa gaaaagagct aacatagaga ctcatagaaa gtatgaagga
     1681 ctttctatga gtctttgttt ttcaaaatag gtatataaat aacatatgaa ttcttttttt
     1741 gttttatgat aaaaatatgt agtacctaaa gtacccaaag tgaccaaaat atacttgata
     1801 aaaaatgagt gagaaaagta aagtgaaata aaaaattgtc actttaggta ctttggtact
     1861 tagtaaagga ttatttattt cactaaagta tataaaacgg aattaataca ggatacatag
     1921 aaaatttgtc atactttcta tgtgtccata ttaagtaaag attccccgtt ttcccgttaa
     1981 atttaaaaga taaa
//
LOCUS       DAFEML010000145         1979 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFEML010000145
VERSION     DAFEML010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.152"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(325..528)
                     /locus_tag="LP468_002723"
     CDS             complement(325..528)
                     /locus_tag="LP468_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082185.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="LP468_002724"
     CDS             complement(728..1744)
                     /locus_tag="LP468_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL2082186.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          557 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAFEML010000146         1927 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFEML010000146
VERSION     DAFEML010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.153"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            283..522
                     /locus_tag="LP468_002725"
     CDS             283..522
                     /locus_tag="LP468_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082187.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="LP468_002726"
     CDS             complement(884..1144)
                     /locus_tag="LP468_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082188.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="LP468_002727"
     CDS             complement(1329..1826)
                     /locus_tag="LP468_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL2082189.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT          615 a          361 c          264 g          687 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaat
//
LOCUS       DAFEML010000147         1854 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFEML010000147
VERSION     DAFEML010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.154"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(34..1065)
                     /gene="queA"
                     /locus_tag="LP468_002728"
     CDS             complement(34..1065)
                     /gene="queA"
                     /locus_tag="LP468_002728"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL2082190.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1258..>1854
                     /locus_tag="LP468_002729"
     CDS             1258..>1854
                     /locus_tag="LP468_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2082191.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT          533 a          390 c          348 g          583 t
ORIGIN      
        1 tttgttattc aaaactagcg gcttttcata accttatttc acgaacatcg catctccaaa
       61 actaaagaaa cgatagcgct cttcaatcgc atgctggtaa gcagataaag tcaattctct
      121 tcctgcaaag gcactaacta acatgactaa agtcgatttt ggcaaatgga aattagttga
      181 gaaagcttct accactttga attcatagcc aggcgtaatg aaaatatcag tccatccgct
      241 gtctgctttg atttctccat taaatttcgt tccaatcgtt tctaatgttc gaattgaagt
      301 tgttccgaca gccacgattt tcccgccatt tttacgtact tggttcaatc gctcagccgc
      361 ttcttccgtc aaacggtaga attcactatg catatggtgt tcttcaattt tatctacgct
      421 gacaggtcgg aatgtaccta accctacatg tagtgtcaga tagactaatt caacaccctt
      481 tgcttcgatc tcatcaagta attctttcgt aaaatgcaat ccagctgttg gcgctgcagc
      541 agaaccattt tctttcgcat agacagtttg atagcgatct gggtcttcca gacgttcttt
      601 gatatatgga ggcaatggca tttctcccaa tgattcaaga atctctagaa aaattccttc
      661 atactcaaag tcaatgatcc gtccgccgtg ttccaattct tctttcacta ctgcttgcaa
      721 tctgccatca ccaaaagaga ttcttgtccc aactttggca cgtttcgcag gtttgatcaa
      781 tgtctcccac gtatctcctt gtgtattcgt tagaagaagg acttctaaat gcgcaccagt
      841 atctggtttt tctccatata aacgagcagg cagaactcgt gtattattca taactagcgc
      901 atcaccaggc tgtaactctt caatgatttc atggaaatgt ttatcttcca tctctccagt
      961 tttccgatcc aaaacaagta aacgagaatg atcgcggtct tttaatggtg tttgtgcgat
     1021 taattcttcc ggcaagtcaa aatcaaaatc ttctgttgtt aacatatcgt cactcacttt
     1081 ctatcatgtg cttcatcatt ctatcatgtt tttcgttctg ttggcaaaat cagcactttt
     1141 tcacttctat tttttgtttt cctaaataaa aaaactaccc tatttgtatt ttttcattgt
     1201 tttaggcata ctagtaatag atagttcttc attgaaaata gaaaaagagg tggcaccatg
     1261 attgaatttc aaaatgtgtc aaaaatttat aaaggtggaa aagtcgctgt agaggacgtc
     1321 aatctttcat ttgaaaaggg tgagttcatt tgttttatcg gtacgagcgg aagcggaaaa
     1381 acgacgacga tgcggatgat caaccgaatg actgatccaa cacaagggaa aattttgatt
     1441 gatggaaaat ccatccaaga aattgatcca gtggaattgc gacgtcagat cggctatgtt
     1501 atccaaagta ttggattgat gcctcacatg acgatccgtg aaaatatcac tcttgtccaa
     1561 aaattgttga aagtcagtca agaagaacgg aataaaacag ctgaaaaaat gattgatctt
     1621 gtggaattgc cccgtgagat gttagatcgc tacccacatg aattatctgg tggtcagcag
     1681 cagcgtattg gagtcgttcg tgcccttgca gcgaatcaag atatcatctt gatggacgag
     1741 ccattcggtg cgcttgatcc aatcactcgt gattccttgc aagaccttgt caaagattta
     1801 caagagcgtt tgggaaaaac gatcgtattt gtaacccatg acatggatga agcg
//
LOCUS       DAFEML010000148         1742 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFEML010000148
VERSION     DAFEML010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.155"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            96..506
                     /gene="spx"
                     /locus_tag="LP468_002730"
     CDS             96..506
                     /gene="spx"
                     /locus_tag="LP468_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2082192.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     TLAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLLKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="LP468_002731"
     CDS             520..876
                     /locus_tag="LP468_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2082193.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVEKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            1547..>1742
                     /locus_tag="LP468_002732"
     rRNA            1547..>1742
                     /locus_tag="LP468_002732"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          621 a          275 c          337 g          509 t
ORIGIN      
        1 ttattttgat ttttttttat attttattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagacc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attgaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtagaaaaa aaacaactga tttttttatg cacacaacat
      781 accaacctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattc catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1141 ttgttgacat gttagaaatg acatgataag ataactgagt ccttaaaaaa ggaccgcttg
     1201 cgaagcttga ttctatcgaa aaaacttcaa aaaagttctt gacaaataac aaacgacaag
     1261 ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa
     1321 gagttgacaa ttacttgtct ctctgatacg atataaaagt tgctgcggca gccaaaaacg
     1381 aatcgggaaa cactcctgat gaagtagacc tttgaaaaat gaacaaagta agacaaacca
     1441 aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca tttttaacaa gcaagcaata
     1501 tgctagcaaa caaattgagc ttaacaatcg caaggttgtt cgaacttttt atgagagttt
     1561 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg aacgcttctt
     1621 tttccaccgg agcttgctcc accggaaaaa gaagagtggc gaacgggtga gtaacacgtg
     1681 ggtaacctgc ccatcagaag gggataacac ttggaaacag gtgctaatac cgtataacaa
     1741 tc
//
LOCUS       DAFEML010000149         1679 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFEML010000149
VERSION     DAFEML010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.156"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(366..1658)
                     /locus_tag="LP468_002733"
     CDS             complement(366..1658)
                     /locus_tag="LP468_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2082194.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
BASE COUNT          516 a          343 c          285 g          535 t
ORIGIN      
        1 gtatgggcta ctctgtgata cttattagcc attaaactat tttacccaca tagcatatat
       61 tttgaaatcg ttcattccgt aaattcaact aaatatgcct aaaaaaataa aaaatctaag
      121 atagaataag atttattcag tcttagatgg atttatagca actttttcgt aacaacttta
      181 aaaaatacga aaagaaagag ctgttttact ctgactacgt tgctaaattg tcgtttaatc
      241 attcatttaa accaaatctt tttttataga attcgtttta atcctcctga atccaaaaac
      301 tatgaaaacc gtaattaaat agttaagagt ttttaaccac cataattctc tcggctattt
      361 tgaaatcaga taaattttga tcggacacat agttgaataa acctaccgtt gttacggaag
      421 gtaaatcgca tacttttcat tctagaggag aaggtctcgt tgatcattaa ctgattaagc
      481 accatagccc agttttgaat tcgaccacct gaccacttcg cgtgtaattc tttcgtgcgt
      541 aaataaagta gttttaggag tgcattctca ttagagaacg ctcctttttt tgtgactttt
      601 ctgaagctgg agtggacact ttcaaccgca ttggtagtgt acataatttt tcgaatggca
      661 ctaccataat caaatagttg ttcaacatgt gcaaagttcc gtttccagac atctacagca
      721 ccagaataat gagaccaccg attttgaaaa ctgtcaaaag cagcatgtgc agcgtttaga
      781 gaagaagcac cgtagaactt tttcatatct cggcagactt ccttatagtc cttacttgga
      841 atatagcgca atgcatttcg aacaagatga acaatacagc gctgaacaat taccgatgga
      901 aagatcgctt ttgcgccttc ttcgaggcca gaaacaccgt ccatcgaaat gaaaaagaca
      961 tcttcgacac cacgtgcttt cagttcatca aatacttgca tccagcgatt tttagattct
     1021 gtttgattta accataatcc taaaatctcc ttatttcctt tgagatcata gccaagaatg
     1081 gtgtatacag catattcttt ggcttcataa ttttctcgta aagtaacata catacaatca
     1141 acgaatagaa aggcataaca ctttgctagg gggcgggctt gccattcttc caattcagga
     1201 aggacagcgt cagtgatatc tgaaatcatt tcatgggaaa tatcaaagcc ataaatagct
     1261 tcgacggttg cggcaatatc tcgttgactc attcctcgtg catacatgga aagaaccttc
     1321 ccttcgatgt cggagacatc tcgttttctc ttaggaatta actctggttc aaaggaagct
     1381 tcccggtctc taggaacatc aatagctact tcaccaaaac tggttttaag cgttttagtt
     1441 ccatagccat ttcgacggtt atcgtgttcc ttaggctctt tagaatgggc atcataacct
     1501 aaatgattat tcaattctcc ttgaagcatt ttttcaaaaa ggggcccaaa cacatctttc
     1561 aaagcatctt gcatgtcatc gacagattca ggttgatagg cattcagaat ggattcagct
     1621 aacttttcgg catcaggatt tcttttcttt ctagccatcg tgtaatcacc tcttgatct
//
LOCUS       DAFEML010000150         1579 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFEML010000150
VERSION     DAFEML010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.157"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            39..590
                     /locus_tag="LP468_002734"
     CDS             39..590
                     /locus_tag="LP468_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBL2082195.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1520
                     /locus_tag="LP468_002735"
                     /pseudo
     CDS             1266..1520
                     /locus_tag="LP468_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
BASE COUNT          604 a          224 c          288 g          463 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggag
//
LOCUS       DAFEML010000151         1574 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFEML010000151
VERSION     DAFEML010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.158"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            237..1454
                     /locus_tag="LP468_002736"
     CDS             237..1454
                     /locus_tag="LP468_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2082196.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT          504 a          342 c          296 g          432 t
ORIGIN      
        1 ggaacatcat tgacgaatga tgttctcctc tattttctat ttttagatta tagtgaagag
       61 tgaaagaaag ttcgaacaaa gccttgagga ctacgagtcc ctatcaaaaa ccgaacttct
      121 ttactgtcat tttagaatca ggtttacgta tgttggggcc atgagcccgt gtataggaaa
      181 ttggaatcga aatgaagcag taaagttctt tcaaaactta aaaaggagga aaacaaatgc
      241 cttacattct tgcattagat gtttcaatgg gacacagcta cagtgtccta tacaaagacg
      301 acacctgctt atttgaagac gagattgaac acactcaaag aggatttcat gcattactcg
      361 aagagatcca gcacttgcct gagcgtccat tgattgtttt tgaagcaacg gggatttatt
      421 ccagaccagt cgaaaagttc tttcaagatc atcacttttc ttactgtttg ttaaacccgt
      481 tagaggcgaa aaaacagatg gaagaaagca ccttacgcag ttggaaaaca gataaatcgg
      541 atgcccaccg gctcgcacag actcatctta aaaatcaacg tcagccaaaa gaagtacaaa
      601 gcaattttta cttagagatg cgcgatttag cccgttttta tcaagaaatt gagaagaaaa
      661 tcactcgtct gcgcatggat ttacacaact gccttcaatt gacttttcca gagcttgaac
      721 agttcttttc aaacaggctg accccttacg cattgacatt gatccgtctt tttccccatc
      781 cagattttgt attggcatct actcggacaa aaataaaaaa taaactgatc aacgaaacac
      841 ggaaaaaaat ctccgcgaat cgtgccgagc aaaaggcaga tcaaatcatc cactatgcac
      901 agtgtgccta tccagctgtt gaaaaagaca gtatccactg tcaaaaaacg atctattacg
      961 ccgaacttct ccaagattta ctcgaacaaa aaaaagcact ggcgacacaa atgatcaaaa
     1021 aagccgaagg ctctccttgc tttttgttgt accaaacgtt ccctgggatt ggcgcactca
     1081 cagccgcttt attgctcggt gaattaggag atatcacacg atttaaaacc cataaacaat
     1141 tgaatgcctt tgtcggaatc gacatccgac ggtatcattc aggtaagtat actggccaag
     1201 accgcatcaa taagcgtggt aatcccaaag cacggaaaat tattttcttc accattcgaa
     1261 atatgattcg ccagcaacgc gcagctccta atcatattgt cgattattac tacaaattaa
     1321 aaaagcaacc tatccctaag aaagataagg ttgccacagt tgcttgtatg aacaagcttc
     1381 tgaaatgtat gcacgctatg gttagggcac atacagagta cgactatgcg tacgcggtct
     1441 cagtggacca ttaactaaac cacttacagt ataccacttc tttgcccaga tcgaaaattt
     1501 tttacgaacg gggctttatt tggtgtgctt tgattttgtc gctttcgttt acgagctatt
     1561 tttcttgcac cttt
//
LOCUS       DAFEML010000152         1456 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFEML010000152
VERSION     DAFEML010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.160"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            108..1040
                     /locus_tag="LP468_002737"
     CDS             108..1040
                     /locus_tag="LP468_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL2082197.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="LP468_002738"
     CDS             1112..>1456
                     /locus_tag="LP468_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082198.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAFEML010000153         1433 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFEML010000153
VERSION     DAFEML010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.161"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            97..1398
                     /locus_tag="LP468_002739"
     CDS             97..1398
                     /locus_tag="LP468_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2082199.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          469 a          289 c          262 g          413 t
ORIGIN      
        1 atcattctat cggtcccttt tgagcatgaa aaaacaaaac atacagaagc tccgttagaa
       61 ttgaatcacc acaacacaat caaaggagcg ttctgtatgc ctgatcttca tcatatcaaa
      121 ctactacttg gaatcaaaga taaaaacatt ttcatcacaa atgtggaatc gaagagcatt
      181 aagaatatca agagtcttgt tgtttctgcg acgttaagta aagaaattcg tcgctgtcct
      241 ttgtgtaaac agatgaatca tgaaggcatg atcgttaaga acggaaagaa aaaatcgctc
      301 attcaactta ataaatgtgc gaaccaactg acttatcttg ctttagcgaa acaacgctac
      361 cactgtcgtg gctgccacac ctattttacg gcgaatacct acattgtcga tagaaactgc
      421 tttatcgcta aacaagtgcg ctataaaatt ttagaagagc taactgaaaa acaagcaatg
      481 acgacaattg ctaagcattg cggcgtttct tggtcgaccg tttctcggac actcgcttct
      541 ctgatcccca tgacaaaagt aaaaagaaat tggttaccgc gttgtttatt aatggatgaa
      601 tttcgttcac tgaaaaatca agtcggtccc tactcctttt cttgtatgga tggcgatact
      661 ggaaaattac tggatattct tccttcacgg aagaaaaagg ctctcgtttc ttattttatg
      721 caatttgaac gacgcgcacg attgaaggta aaggtcatcg tgacggacat gaatgtttct
      781 tatgcctctc tgataaagga atgttttcca aaggcaaaac tcgttgtgga tcgttttcac
      841 attgtcaaac atctcattcg taaatttgag gatattcgcg tacgaatcat gaaaagcttt
      901 gatcgaaacg atccaacaca agccaaatat tatcgacaat taaaggcgtt gtctcggctt
      961 ctgatcaaac gacaggacaa gcttgtttat gacaaatgga ccaaatggcg caattttggt
     1021 tgggcgtatc tcaccgaaag tgaagtggtg gatcgtctgc tttcgatctc tgacgaatta
     1081 cgaatcgcct atttttacta tcaagaaatt cttcaagcgt ttcacgacaa agaggcggac
     1141 actttcttta aacttgtaag aacgatgccc aattccgttc caaaagaact gcattctata
     1201 aaaaaagctt ttataaacta tgaatccggc attcgtttag ccctcgaatt gccttattca
     1261 aatgccaaaa tagaaaatct gcatacccac atcaaagcat tgaaacgagt cgcttatggc
     1321 tttcgaagct ttcggaaaat gaagaccaga attttcttac taaataatct gattacctat
     1381 gaatcaaaaa acatctaaag tagaaaagga attctacctt agatgttctt atc
//
LOCUS       DAFEML010000154         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFEML010000154
VERSION     DAFEML010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.162"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="LP468_002740"
     CDS             complement(150..1337)
                     /locus_tag="LP468_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL2082200.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFEML010000155         1421 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFEML010000155
VERSION     DAFEML010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.163"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            96..1388
                     /locus_tag="LP468_002741"
     CDS             96..1388
                     /locus_tag="LP468_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2082201.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          462 a          291 c          257 g          411 t
ORIGIN      
        1 accagcatct tttttatttt ccaaaacata tagaaaagac accttgaaat cctttagaat
       61 taatttggcg aaccaaccca aaaggaggaa tcaagatgtc ttacactcac cttatcaaag
      121 aaacattaga tattctagac ttatcagtta cttttaacga aaattgtctc acaaaagaaa
      181 aatacaaagg gcaaatctgt catatttatc gtggaaactt gatttataca gcccaagaat
      241 gcatccactg taaacaccag attgcttcag atattgtgcg ttggggtaca acaaccgtcc
      301 ggttgttaat gaacgatgtt tctgaatacc gtacctacct cgaattgaaa aagcaacgct
      361 tcaaatgcaa agcttgtcag cggacctttg tcgcagatac ttctgttgcg aaaaaacatt
      421 gtttcatcag tgagaaagtc cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa
      481 tgacagagat cgccgctcag aaaaatctat cggtctcttc tgtttaccgt attatgaagc
      541 gattttatcg tccgttgaat ccttttcgga caccgttacc taaggtactt tgttttgatg
      601 aattcaaatc agttcggggt gtttcaggtg ctatgagttt catcatgatg gatggacaaa
      661 cacagcgctt attggacatt gtcgagaacc gacaactgcc ttttttaaaa cgttatttta
      721 gtcatttttc acgagaaatt cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc
      781 cttatgtatc gctcgttaaa aagctgtttc caaaagcaca gctgattatt gaccggtttc
      841 acatcgtcca acatattggt cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac
      901 tattaaaaag caaagaacaa aaacactatc aattaggtaa gcaattaaaa agatactgga
      961 aacttcttca aaaagatgaa cgcaagcttg attatactcg acgcctttgg cgacctggct
     1021 tcaaagctca tttaacagag accgatattg tggatcgctt actgaaaggg agccctgctt
     1081 tgcgtgtagg ctatcagtta tatcaagact ttctttacgc tgtaaaggaa cgagactacg
     1141 tatcgtttga agaactactt accaataata tcatgcttcc cgaaggctat cagacgacct
     1201 tgagaacgtt ccagaaattt ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa
     1261 atggcccact tgaatgtctg aacaaccata tcaaagtgtt aaaacgaaat gcatatggct
     1321 ttcgtagctt ttataatttc aaattgcgca tcatgattcg tcatggcaac gcattgattt
     1381 tcaactaaaa aagatcaaga ggaactgatc cacttgatct c
//
LOCUS       DAFEML010000156         1355 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFEML010000156
VERSION     DAFEML010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.164"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..1355
                     /locus_tag="LP468_002742"
     rRNA            <1..1355
                     /locus_tag="LP468_002742"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFEML010000157         1325 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFEML010000157
VERSION     DAFEML010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.165"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            278..820
                     /locus_tag="LP468_002743"
     CDS             278..820
                     /locus_tag="LP468_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082202.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFKKNTSEEKNLKL"
     gene            976..>1325
                     /locus_tag="LP468_002744"
     CDS             976..>1325
                     /locus_tag="LP468_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBL2082203.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          534 a          157 c          247 g          387 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gttcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 taaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccaga
//
LOCUS       DAFEML010000158         1316 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFEML010000158
VERSION     DAFEML010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.166"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(56..129)
                     /locus_tag="LP468_002745"
     tRNA            complement(56..129)
                     /locus_tag="LP468_002745"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(93..95),aa:Ile,seq:cat)
     gene            complement(318..1310)
                     /locus_tag="LP468_002746"
     CDS             complement(318..1310)
                     /locus_tag="LP468_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL2082204.1"
                     /translation="MSLLTALFLLPINGFAYTINNEFNLGANEGSSQVANNQYILLHE
                     TANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQ
                     IELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGD
                     HTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNY
                     AHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYN
                     TSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          373 a          268 c          247 g          428 t
ORIGIN      
        1 tgtataatac tcttcaaaaa attctaacac agaacgattc aaatggctac gttaatgtac
       61 cctgtaggac tcgaacctac gaccggacgg ttatgagccg tctgctctga ccaactgagc
      121 taagggtact ggttgttgcc acataaagcc ataaacaatc aaccagtaga atgtgtggca
      181 acaaacctgt tatcgcatag cttggagtgt gactattatg ggtgatagtg aagatatgcg
      241 ataacatcac tattttatcg aatgattttt atagttgtca atatagttat gtaatgctcc
      301 tcaacgagga gctattttta tcgtttagga atatttaaat accaacgttt gtcatggaaa
      361 tcttgcgcac cgcctttagt gtttccctct ggatcattcg ttgcccgcat catgacatag
      421 actttcttat tagggaagtt acgcatgtta aaagatacat gatagccaac atttccagaa
      481 gtattataag cttgatttac atctgatcta taaattccat cagctcttac tcgagctaat
      541 tctttcccag tattgtaatc cataatgaag atatactcgt atttatagtt agcaatgtgc
      601 catccagcta catgcaaatt tgcattttcg atttctccaa actgatcaat gtgggcgtaa
      661 ttcgttccat ctgtcagtgt aggattagct gcaccagctc gtgttggatc aatgacaggc
      721 ttgttttcag aagttgttgg attttcatcg gtaaatccat gagctaaatc atatgctaat
      781 ttttctttac ttacgcccat ttcagaaaga taaccgtaag gatctgtatg atcgccccag
      841 atgttttgtg ttacccataa atgcgatttg attcccggtt ggttataagg agtgtccaac
      901 gttaatggaa taccatattt cattgctgaa tctctagcca attcaacgta tgccttgtag
      961 tttttctcaa acgttgcttt atcatgtgtg tgttgtaact caatctgcac aggactgttg
     1021 gcattagcat acgaaccagc accgtactgt acataaccag gttgaccgac ttgataaaca
     1081 attccgccgt ctcccacaat ataagcagta taagcgctag tccatgaacg ttgcatatac
     1141 tgcgcttcat tgcgtcctgt tgctgtttca ttagccgttt catgcagtaa aatatactga
     1201 ttatttgcta cttgtgagct accttcattt gcgcccaaat taaattcatt gttgatagta
     1261 taggcaaatc cgttaattgg caataaaaaa agagccgtta acaggctcat cgcagt
//
LOCUS       DAFEML010000159         1312 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFEML010000159
VERSION     DAFEML010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.167"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            82..>1312
                     /locus_tag="LP468_002747"
     CDS             82..>1312
                     /locus_tag="LP468_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL2082205.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYG"
BASE COUNT          444 a          257 c          251 g          360 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg at
//
LOCUS       DAFEML010000160         1310 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFEML010000160
VERSION     DAFEML010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.168"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1095)
                     /locus_tag="LP468_002748"
     rRNA            complement(<1..1095)
                     /locus_tag="LP468_002748"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          291 a          366 c          251 g          402 t
ORIGIN      
        1 cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg ggaccttagc
       61 tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt ctgactcccg
      121 gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat gggcccctag
      181 tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa agctatttcg
      241 gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca cctcatcccc
      301 gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc ttcaacctgg
      361 acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc ctattcagac
      421 tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt aactcgccgg
      481 ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt gtaggcacac
      541 ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc tcacggtact
      601 ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc cggattccga
      661 cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca catttcgtct
      721 acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct gaaagaacta
      781 ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt ttcccgtttc
      841 gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact tagatgtttc
      901 agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca tcctattaaa
      961 gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag ctccccaaag
     1021 catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc accgtgcgcc
     1081 cttattcact taaccttatc aaccttgcgg ttgggttttg atccttcttc tagcgataga
     1141 agttagatca agaaaataag caattgaact tattaaaaaa ctctatccag ctcacaaatc
     1201 agcctgtgcg gcaaaaagat cgatcgtctc ataaaatcaa agattttata gccgtccgcc
     1261 tattttgctt taggctaaac aatttgttca gctttcaaat tcaacgcggt
//
LOCUS       DAFEML010000161         1294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFEML010000161
VERSION     DAFEML010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.169"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..1244
                     /locus_tag="LP468_002749"
     CDS             <1..1244
                     /locus_tag="LP468_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL2082206.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAFEML010000162         1253 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFEML010000162
VERSION     DAFEML010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.170"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(304..377)
                     /locus_tag="LP468_002750"
     tRNA            complement(304..377)
                     /locus_tag="LP468_002750"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(341..343),aa:Ile,seq:cat)
     gene            complement(932..1246)
                     /locus_tag="LP468_002751"
     CDS             complement(932..1246)
                     /locus_tag="LP468_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082207.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          469 a          196 c          190 g          398 t
ORIGIN      
        1 ttaatggctt caaatataaa agagtttaaa gcgtaacaca cttatgggga agtggttttt
       61 ggggaacgct ttaaactctt ctttattatt atctcacaat ataacccaaa tgtctttcca
      121 tttaaaaatc aaagtaaaac ttttcaaata tacagaagta taactatgtg aaacatcctt
      181 tcattaatcc ataaaaggat acataaaaaa gccactcatt tgagtggcaa tgaagaaaag
      241 ctttagcttg tataatactc ttcaaaaaat tctaacacag aacgattcaa ttggctacat
      301 taatgtaccc tgtaggactc gaacctacga ccggacggtt atgagccgtc tgctctgacc
      361 aactgagcta agggtagtgg ttgttgccac ataaagccat aaacaatcaa ccagtagaat
      421 gcgtggcaac aaacctgtta tcgcatatct tggagtgtga ctatttatga gtgatagtga
      481 agatatgcgt ctccatatat gtatggttga gacagataaa catgtatgaa aaacgttgtt
      541 aaatcaacgt ttttttattt tggtcaagga gagaaaagta gagaaataca aaattttttg
      601 cattgatttt gcattcaaaa aaacattcaa acatttagaa atccccaata cgtattcagg
      661 aaaatctatt ttaaggttta caaaaagaac ttttgttcgt acactctttt tgaggtgaac
      721 ttttatgctg atggaaggaa aaacacaatt atggtttaag catgttcctt caaataagtt
      781 ttttaattat aaactctaga gaaattaatt catcctaaca taaaataatt gttcactcaa
      841 aagtttttct agaacaatta aaacagcagg cttcacattc gctatacatt tgtaagaagt
      901 aataattcct gtactaaaag gcataattgc tttaattatt ttttgacttc tcttcaaaca
      961 caagaagtag ttgtgtaata attgcagaaa taaggattcc aataatagat ataaaatttg
     1021 acatggaaac gtctataaca ttaaaagaat aaagtgttga agaaagtaaa ctgattgaaa
     1081 taacccctcc gtaaaaaata gtctgtgaat atacccactt tttttcagaa gacgtacttc
     1141 gtttggttct aaaacctatc cctgcatttc tactcttatc aaaaaaccaa atatttagaa
     1201 gtaataatat tgctattatt aagataaaat tactgtaaaa atccaaaagc tat
//
LOCUS       DAFEML010000163         1193 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFEML010000163
VERSION     DAFEML010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.171"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..1076
                     /locus_tag="LP468_002752"
     CDS             <1..1076
                     /locus_tag="LP468_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2082208.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAFEML010000164         1188 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFEML010000164
VERSION     DAFEML010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.172"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            141..398
                     /locus_tag="LP468_002753"
     CDS             141..398
                     /locus_tag="LP468_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082209.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LP468_002754"
     CDS             complement(630..1061)
                     /locus_tag="LP468_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL2082210.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAFEML010000165         1175 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFEML010000165
VERSION     DAFEML010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.173"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            1..405
                     /locus_tag="LP468_002755"
                     /pseudo
     CDS             1..405
                     /locus_tag="LP468_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            560..1135
                     /locus_tag="LP468_002756"
     CDS             560..1135
                     /locus_tag="LP468_002756"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL2082211.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
BASE COUNT          408 a          177 c          251 g          339 t
ORIGIN      
        1 cctcgattac gaaaagtacg atcgcattgg ttttaacacg ggtaattctc gtaacggctc
       61 ctatgaccgt acggtcaaga ccgagtatgg ggaacttcat ctccagattc cgcgcgaccg
      121 caatggcgag ttcaagcaac agactgttcc tgcttataga cggacgaatg acacattaga
      181 ggagaccgtc attcacctct tccgaaaagg tattaccatg tcggaaatcg cagacttgat
      241 tgagaaaatg tatgggcatc actacacgcc ccaaaccatg tccaacatga ctaaagtgct
      301 gactgaagaa gtaaatgcat ttaaagttag aactctaaat gataagtatg tcgctatttt
      361 catgattcct tcagtttttc agatgatata ccactcaaaa aacaatatga gagatgttca
      421 ggaataccat ctctaatggc ttataaattg gttttaggga tagtagatgt tatagacata
      481 tcaaggaata aacgagcagc tgcataaaag cagatggaat taaggaataa ttgaattgta
      541 aaagaaggga ataaatttaa tggcacaatt attttacaga tatggaacaa tgaatagtgg
      601 aaagagtatt gagctactga aagtggctca taattatgaa gaacaaggga agagagttat
      661 cataatgaca agcgcaatag atactcgatc aggatttgga aaagttgaga gtcgtatagg
      721 tgtttcgaaa ccagctattg caattacttc tgaaatggat gtgtacggag aattagtgga
      781 gattattgat cagtacggaa aagttgattg tattttggtc gatgagtctc aatttttaag
      841 tagagagaat attattgatc tatcacttat cgtaatgaat gaggaagtac cagtaatttg
      901 ctatggattg aagaatgatt ttcaaaataa tctcttcaag ggatccgaag cattattgac
      961 atttgctgat aaaattgagg aaattaaaac tatttgccat ttttgcaata aaaaggctgt
     1021 aatgaatgct cgtattgttg atggtattcc agtttattca ggtgaacaga ttgtagtagg
     1081 aggtaatgaa gattaccttt cggtatgtcg caaccactac tacaacgaag attgaaataa
     1141 aaaacgtgta atcaaataat tgattacacg ttttt
//
LOCUS       DAFEML010000166         1091 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFEML010000166
VERSION     DAFEML010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.174"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LP468_002757"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LP468_002757"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL2082212.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAFEML010000167         1090 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFEML010000167
VERSION     DAFEML010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.175"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            233..475
                     /locus_tag="LP468_002758"
     CDS             233..475
                     /locus_tag="LP468_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL2082213.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            472..942
                     /locus_tag="LP468_002759"
     CDS             472..942
                     /locus_tag="LP468_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2082214.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWGKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
BASE COUNT          397 a          125 c          203 g          365 t
ORIGIN      
        1 agaaattgat tgtcgttttc ttttgcagaa atttaagtgc aggcaattat ggtagttgtc
       61 gtaattgctg tcagctcagt gtttatcact gatggtgtga aagatttacg gttggagatg
      121 ttcaataaga ttattggtgc ttaattattt ttattgtagt gctgatatga gaatgttata
      181 attggggtat aaaacataca aataaatttg ctgaaaaatg aggtatcaaa atatggaaaa
      241 tgaattactg gaaaacttag gaagacttca cacaactgaa cttggcgtta ttagaattaa
      301 aaagaactta tctttgaatg tagaaaatgt aattgaatgg tgcaaagaaa aaattagcct
      361 ttctaatgcg gaaatcacaa gaaaaggaaa aaactggtat ataacgattg ataattgtat
      421 tataacggta aatgcgtaca gttataccgt tatcactgct cacaaggtaa aatgataaat
      481 ttttctataa aggaattaaa cgcatttgca gttattgggc aggaagtaga actgactaat
      541 tatcaaaaaa agaatattca gattagtaca cagttttggg gaaagtttaa cagtagtttg
      601 aaaaaagcgt atctttcaca atcaggaaat tgggtaaaat atgcttttat ggaaagaaga
      661 aatggaaaac tttattattt ctgttctatt ccccaaagaa ccattacccc agagggcttt
      721 ctgtataaag aaataccgtc ttataaatat ttggttgtgg agcatattgg tgctatggat
      781 aaaatatatg aaacttatgg caagatttat gaagaaatta ttcctagtac atcgtatatt
      841 cctataaaag atattatcct acactttgaa aaatacgatt atcgttttca ttggaatagt
      901 gataattcag ttattgaaat ttggatacct attcaagatt agaagcaatt ttatatccat
      961 acacacaaag cagttagtct taggattgac tgctttttct atacagattt ttaatgacag
     1021 gcaattatca attatggtag ttgccttttt tgattggagg aattgaagaa tgaatgataa
     1081 aaactttatt
//
LOCUS       DAFEML010000168         1061 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFEML010000168
VERSION     DAFEML010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.176"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP468_002760"
     CDS             complement(36..992)
                     /locus_tag="LP468_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082215.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAFEML010000169         1017 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFEML010000169
VERSION     DAFEML010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.177"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(81..635)
                     /locus_tag="LP468_002761"
     CDS             complement(81..635)
                     /locus_tag="LP468_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2082216.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          332 a          185 c          106 g          394 t
ORIGIN      
        1 cttccgaaaa ttcagttatc ttcattaatc tcaccttcta agttttcatt atacacaaaa
       61 aatatatcct aatatctcaa ttagcctccc aatttaaaac cacgtaacga tgcccctatt
      121 tcatcttcag ttataccaat gtaccttttt gtaattgctt gcgagctatg attaaaaata
      181 aacattaagg tagcaatgtc tctagttttc ttgtagtagt gatacccaaa agtttttctt
      241 aatgtatgtg ttcctatatc atctcttcct aatttttctg ctatatctgc atatatctga
      301 tagacacgat cccttgttat atgtcgacct tgttgccgac ttggaaataa ccaatcattt
      361 tcttctttac cttcagtata taataaaatc tcttctctca aattatctat aaaaatcggt
      421 tttcgcttac ctgttttatg ttcaacaata ataggcttac ttttacctcg tatgtctcca
      481 acttttaatc ctataatatc tgacatacgt aacccattat tgattccaaa caaaaataaa
      541 aaactatctc tttctggatt acttgttctt cttagccaaa actgaaaatc ttgtatctct
      601 tcatttgtcc ttaacggttg tacattatag ctcactattg tttcccttct taaaaatatt
      661 ctgagttcat gattatatat atattttacc ataatcatga acttatatat atactctgtt
      721 aaaagtgaag aaaatcaagg ggtttagttt atgattttat atcatttcag taactcagaa
      781 tattccgact tttttgtaca aaaaaattaa ccttacttat atgaagattc taagctctta
      841 tttaaatttt agacgggcag ttatccgtag aagttcttag aatagctaat ttacataatt
      901 aaattatatg aaatttaaat ttgaacaata tactaagaac tccccttact ataaattgaa
      961 ataaattagc atatgaataa ccgtgctacc aagcttttca ttaataaaat attttta
//
LOCUS       DAFEML010000170         1000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFEML010000170
VERSION     DAFEML010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.178"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            127..>1000
                     /locus_tag="LP468_002762"
     CDS             127..>1000
                     /locus_tag="LP468_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2082217.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDF"
BASE COUNT          358 a          153 c          189 g          300 t
ORIGIN      
        1 tatcccatat tttaaaataa aagatagcgt aaaatatttt gtgtaaatag aaatttaggg
       61 tagaaaaaaa agtccattct gtaaaattaa agttaccaca cagaaatttt ataggaggac
      121 tttctcatga ctaaatttac tatagaaatt atgcaaacac tactcaataa aggggattta
      181 gatgaattat ttcaggatca tttagagcga gcgattaatt cacttctaca agcagagcta
      241 actgcttttt tagattacga aaaatatgat cgaaatggat tcaattcagg aaattcccgt
      301 aacgggaatt attcacgtac atttaaaaca gaatatggcg agttgaattt aactattcct
      361 agagatcgga atggcgaatt ttctcaacaa acactaccag catataagcg aaccaatgat
      421 tcattagaaa cgaccattat ccaattattt caaaaaggca ttactatggc tgaaatctcc
      481 aaattaattg aaaaaatgta tggtcaccac tatacgccac aaacaatctc caacatgagt
      541 aaattggtgg ctgaagatgt tttagctttt aaagaaagaa cgttagaagc caattattcc
      601 gttatattta tggatgcgac gcatatccct gtgaagcgac agactgtttc gaaggaagca
      661 gtgtatatta cgattggtat tcgtttggat ggaaccaaag aagttcttgg gtttactatt
      721 gccccaactg agtctgctta tatttggaaa gaagttcttc aagatcttag aaaacgtggg
      781 ttagaagaag ttttattagt agtgacagac ggattaagct gtattgaaga aagtatccat
      841 agtgtgtatc cgaatgccca atttcaacaa tgttgtgtgc atgtatctag aaatatcgct
      901 cataaagttc gtgttcgagg tcgaaaagaa atttgtgagg atttcaaatt ggtttaccaa
      961 gcgaattcaa aagaagaggc attggatcac atcgacttta
//
LOCUS       DAFEML010000171          993 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFEML010000171
VERSION     DAFEML010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.179"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..>993)
                     /locus_tag="LP468_002763"
     rRNA            complement(<1..>993)
                     /locus_tag="LP468_002763"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          207 a          317 c          220 g          249 t
ORIGIN      
        1 cgtcatcccc accttcctcc ggtttgtcac cggcagtctt gctagagtgc ccaactgaat
       61 gatggcaact aacaataagg gttgcgctcg ttgcgggact taacccaaca tctcacgaca
      121 cgagctgacg acaaccatgc accacctgtc actttgcccc cgaaggggaa gctctatctc
      181 tagagtggtc aaaggatgtc aagacctggt aaggttcttc gcgttgcttc gaattaaacc
      241 acatgctcca ccgcttgtgc gggcccccgt caattccttt gagtttcaac cttgcggtcg
      301 tactccccag gcggagtgct taatgcgtta gctgcagcac tgaagggcgg aaaccctcca
      361 acacttagca ctcatcgttt acggcgtgga ctaccagggt atctaatcct gtttgctccc
      421 cacgctttcg agcctcagcg tcagttacag accagagagc cgccttcgcc actggtgttc
      481 ctccatatat ctacgcattt caccgctaca catggaattc cactctcctc ttctgcactc
      541 aagtctccca gtttccaatg accctccccg gttgagccgg gggctttcac atcagactta
      601 agaaaccgcc tgcgctcgct ttacgcccaa taaatccgga caacgcttgc cacctacgta
      661 ttaccgcggc tgctggcacg tagttagccg tggctttctg gttagatacc gtcaagggat
      721 gaacagttac tctcatcctt gttcttctct aacaacagag ttttacgatc cgaaaacctt
      781 cttcactcac gcggcgttgc tcggtcagac tttcgtccat tgccgaagat tccctactgc
      841 tgcctcccgt aggagtttgg gccgtgtctc agtcccaatg tggccgatca ccctctcagg
      901 tcggctatgc atcgtggcct tggtgagccg ttacctcacc aactagctaa tgcaccgcgg
      961 gtccatccat cagcgacacc cgaaagcgcc ttt
//
LOCUS       DAFEML010000172          991 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFEML010000172
VERSION     DAFEML010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.180"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(21..94)
                     /locus_tag="LP468_002764"
     tRNA            complement(21..94)
                     /locus_tag="LP468_002764"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="LP468_002765"
     tRNA            complement(108..181)
                     /locus_tag="LP468_002765"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="LP468_002766"
     tRNA            complement(209..281)
                     /locus_tag="LP468_002766"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="LP468_002767"
     tRNA            complement(301..374)
                     /locus_tag="LP468_002767"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="LP468_002768"
     tRNA            complement(384..457)
                     /locus_tag="LP468_002768"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="LP468_002769"
     tRNA            complement(468..553)
                     /locus_tag="LP468_002769"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="LP468_002770"
     tRNA            complement(570..641)
                     /locus_tag="LP468_002770"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="LP468_002771"
     tRNA            complement(653..725)
                     /locus_tag="LP468_002771"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="LP468_002772"
     tRNA            complement(743..824)
                     /locus_tag="LP468_002772"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="LP468_002773"
     tRNA            complement(832..904)
                     /locus_tag="LP468_002773"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="LP468_002774"
     tRNA            complement(908..980)
                     /locus_tag="LP468_002774"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAFEML010000173          851 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFEML010000173
VERSION     DAFEML010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.181"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..392)
                     /locus_tag="LP468_002775"
     CDS             complement(<1..392)
                     /locus_tag="LP468_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2082218.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDD"
     gene            complement(407..679)
                     /locus_tag="LP468_002776"
     CDS             complement(407..679)
                     /locus_tag="LP468_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082219.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT          249 a          176 c          125 g          301 t
ORIGIN      
        1 aaatcatcta gtgtattggc acgagacgta atgatcaatc catcgaaagc tttagctgca
       61 aattcttcaa gataccttcg ctctttttct ttatgatagc ccgtcggtaa aagtgtcact
      121 ttgtaatcat aatcaaacgc tgcttcaatg atcccactga tcaactgatc aaaatacgga
      181 tgattggtat aaggcagaat cactccaatg cttttcgttt ttccataact taactgtctg
      241 gcatttgcat tagggatata atcgacttct ttcatgaccg caagtatttc tttccttttt
      301 tcctcatcta catatggatg tccattgatt acacgtgaaa tagtagaaac tgaataacct
      361 gtgagctttg cgatatctcg aatgtttgcc actgctgctt cgccacctat acaaaaagat
      421 tttcttgtaa atagtctacc acagctggac cgcattcaaa aaactgatac atttttcctt
      481 catgcgaaaa actgatccgc tgcccgcccc aatatatatc ttttgtcaaa ttttcgattt
      541 cattcattgg tatttctttt actatattcc tattcaaccc ttgaaaactg tacaacgtta
      601 atacggatcc cttgaactcg acaaacgcat aaaaataatt gttcgttgtg ccatctgtta
      661 tctctacata agtattcatt gcaagccctc cttttgatac tttgagtata gtgtatgaaa
      721 cgcgtctcat agcaaggagt ttgttttgcc aaagaaaagt tttattcctc tttcattatt
      781 accaaagtct cttattttaa attgaataca ttataatgat actgtaaata tatctttatt
      841 attagtgaat g
//
LOCUS       DAFEML010000174          830 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFEML010000174
VERSION     DAFEML010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.182"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..792
                     /locus_tag="LP468_002777"
     CDS             <1..792
                     /locus_tag="LP468_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2082220.1"
                     /translation="EFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFS
                     LATREAVQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRL
                     KGNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPN
                     LRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHY
                     SYSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          263 a          164 c          160 g          243 t
ORIGIN      
        1 gaattcaaat cggttcgaag tgttgccagt gcaatgagtt ttatcatgat ggacggacaa
       61 agccatgcat tattggatat tgtcgaaaat cgacgcttgc cttatttaga acgctatttt
      121 tctcggtttt cattagcgac tcgtgaagcc gttcaattga ttgttattga tatgtatgcg
      181 ccttatgttt cgttggtgaa aaagcttttc ccgaatgctc agttgatcat cgatcgtttc
      241 cacatcgtcc aacatattgg cagaactttc ttgaatcatc gagtgaaaga aaccacggta
      301 cgacttaaag gaaattccca ctctcaacga gggttaggga aaaaattgaa gcgctattgg
      361 aaactcctac aaaaagaaga agcaaagtta aactatgaaa aacgggtttg gcgtgccagt
      421 tttaaagatt atttgactga aagtgagatt gccgatcgac tgttagctgc ttgtcccaac
      481 ttacgccaag gctatcagtt ataccaagac attctttatg cggtaaagaa aagagatcag
      541 tcactatttg aggattgttt aactagagac attagcggtc tgccagaaac ctatacaacc
      601 actttacgaa cgtttaaaaa gtttctgcca cagatccaaa atgcgcttca ctacagctat
      661 tcaaacggac cattggaatg cttaaacaac cacatcaaag tattaaaacg caatgcgtac
      721 ggctttcgca acttttacaa tttcaaacta cgaattatga ttcgtcatgg caaaacattt
      781 ttaaccaaat aaacagaaca gaaagaggtt ttcttctttc tgttctgtcc
//
LOCUS       DAFEML010000175          816 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFEML010000175
VERSION     DAFEML010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.183"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(257..517)
                     /locus_tag="LP468_002778"
     CDS             complement(257..517)
                     /locus_tag="LP468_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082221.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          329 a          123 c           97 g          267 t
ORIGIN      
        1 atcttattgt agaaaaagaa aaaccgcgaa gcaaccacct gcctaggatt aatggttact
       61 tacacggttt atattacact ctcatcatta aaaaagtatc tttcgatatt actaaacaat
      121 gaaattatct atttgaaatt taaatctgat aatatattga gtgttccaat gagggctttg
      181 atcctattat ccatatcttt ttcagtttta atattgatac acattataag aaaaagaaac
      241 ttttggttaa tttatttcat cccagtgcaa aatataaaaa agtaaaatag accataggca
      301 atagattaac aattaatata atacaagcaa atattctatt cattgtattt ctgctttcaa
      361 aaagttctaa tattgaaagt ataattccac aaatgcctat aataagtatg ggaataagat
      421 tagaaaataa caccccgagc caatctgtga aaattactat atttactaat atccctatta
      481 acatacctat catatttatt aaatcaattt ttttcattag atatttctcc tttattaaat
      541 ctgaagtact tatattaaaa taattctaaa ctatttacct caaaaagtgc aataaattat
      601 ttctgaacaa taaaatgata gtcaaaacaa aaaaatattg ttaatcgttc agagccatcc
      661 gagagtgtaa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa ggcgcttctg
      721 tagaataaag ttaacgacaa ccaattcaca gaaaagagga cttccctatg aatgatttta
      781 ctacagaaat tgtgcaaact ctagtcacta aaggcg
//
LOCUS       DAFEML010000176          791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFEML010000176
VERSION     DAFEML010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.184"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..782
                     /locus_tag="LP468_002779"
     CDS             <1..782
                     /locus_tag="LP468_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2082222.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAFEML010000177          790 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFEML010000177
VERSION     DAFEML010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.185"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(36..236)
                     /locus_tag="LP468_002780"
     CDS             complement(36..236)
                     /locus_tag="LP468_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2082223.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            632..781
                     /locus_tag="LP468_002781"
     CDS             632..781
                     /locus_tag="LP468_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082224.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          258 a          130 c          126 g          276 t
ORIGIN      
        1 tttctttcga aaagacggtt aaaagtcaat ttttattaag ctttaacaat gtttgttgct
       61 tgagggccac gttgaccatc ttcaacatcg taagacactg cttggccttc ttctaaagtt
      121 ttgaagccgt caccttggat agctgaaaaa tgtgcaaata catcatttcc atcttcacca
      181 gtgataaagc caaaaccttt gtctgcgttg aaccatttta ctgtaccgtt attcataaat
      241 aaattcctcc tgatacgtat caatgtacgt tttttcgttg caataaatat ttgataggca
      301 aaaggagttt tatctatgta gatatatcgc tcaaattacg tttcaaaata gattactcat
      361 ttaatatatc atgctttttc taataacaca aggataatgc aatgaaatat aaaattcatt
      421 gtcttctatt gtcttcgaat cgaagaaaaa gttgaataac cgcgattgat tcactttttg
      481 ttttcttgtt tatttgcttt tatctgcaac ttttgacttt aaaatttctt aactatgaaa
      541 acctttcaat tggtggtata cttataaatg gaatttcgtt atcaacgcgt tcgttgcctt
      601 tcagcaagta tttaaagaaa ggagaatggc tatgacattc tataacaaag atatacaata
      661 tcgagtaacc ttggatacag atttgaatct atttgtcgtt tttgacaaag aaaataccaa
      721 tcatgtagcg acaggtgtta cgatcgaaca agcagtgcaa gaattaaaaa aatctgcata
      781 aggagtggaa
//
LOCUS       DAFEML010000178          735 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFEML010000178
VERSION     DAFEML010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.186"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            220..>735
                     /locus_tag="LP468_002782"
     CDS             220..>735
                     /locus_tag="LP468_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2082225.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT          255 a          114 c          163 g          203 t
ORIGIN      
        1 ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt
       61 cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat
      121 ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag
      181 gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta
      241 acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag
      301 cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga
      361 ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg
      421 ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat
      481 tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct
      541 attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac
      601 agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca
      661 atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa
      721 agcagaatga tagag
//
LOCUS       DAFEML010000179          731 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFEML010000179
VERSION     DAFEML010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.187"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="LP468_002783"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="LP468_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL2082226.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="LP468_002784"
     CDS             complement(481..675)
                     /locus_tag="LP468_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082227.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DAFEML010000180          719 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFEML010000180
VERSION     DAFEML010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.188"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            64..240
                     /locus_tag="LP468_002785"
                     /pseudo
     CDS             64..240
                     /locus_tag="LP468_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            289..675
                     /locus_tag="LP468_002786"
     CDS             289..675
                     /locus_tag="LP468_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2082228.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT          250 a          106 c          153 g          210 t
ORIGIN      
        1 aagtagataa aaagctgttc caagctcgag ttacgagttt ggaacagctt ttgtctacag
       61 tctgaaacag ttgagactgt tttttcttcc ttagaaaaat taggttgtca aaatttcaac
      121 tcacgttctg ttaaagggct agagagtaga tttgaaagca tattactggc ttacagtgtt
      181 ctattaagtc gagcacaacg acgttttgaa ggaactttga gatattcttt aggatattaa
      241 aattaactag caccacgggt ataataaaaa taaaaaagga gatctttcat gaaaaaaatt
      301 ttagggttga tcgttatcat attgattgct tttataggat ggaaaggttg ggactactat
      361 cagtctactt atgtaggtaa agattattat gcggtagtca aagctccaat gcctgcagaa
      421 actgatatca aagcagataa tggggaagta attggaagag gttttaaata caacgtagat
      481 gcttatgctg aaaacggtga aaaaagacag ttagatttcg atgtcattac ttctggtgac
      541 tctgccaatg gttctgctta ccccgaagga acgatcttgc agttgaaagc aagcgaaaag
      601 cggatcatag agaaaaaagt aattaccagc gataaggtac cctcatctgt aaaagaaaaa
      661 ttaggcctat cttaagctaa gaatatatcg caaaaaagca ctcgaagtga gtgcttttt
//
LOCUS       DAFEML010000181          706 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFEML010000181
VERSION     DAFEML010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.189"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..126)
                     /locus_tag="LP468_002787"
     CDS             complement(<1..126)
                     /locus_tag="LP468_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2082229.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVY"
BASE COUNT          274 a           93 c           97 g          242 t
ORIGIN      
        1 atagacatta taaatggttt gtcgagaacg ttgtaccaga tgggctactt ttgaaacaga
       61 gtgtgattga ttgaaataag cttctatcat tacgagttca gttggtgtaa gatgggtata
      121 ggtcatttgt actcactcct tataattctt tcgacggaac tattttgagt gtagcacaaa
      181 tgactttttt agttgtctag cttaatttta caatcggcga aggtaaaaaa ataaaaaaat
      241 gtgacaagtg ttttgaatca gctgtggtaa agtttcctca atttaaacta aatccagctg
      301 cctcgataca atttcaagga catgtatttg atgttttagc taaagataac ataaaaaaat
      361 acaaaaaagg taatatattc catattgata tacaaatatc ttctaattta gaagatataa
      421 aaaaagcctt taaaattaaa acaattggca ctgctcctaa ttttaaataa caaaaaaatt
      481 actagataat ctaaaaacag gatggcatta tgagaacaat aactaaactt cctatatcac
      541 atattttgta attagtgaaa agcaaattga ctactatcat aagttaatga ctctcatctt
      601 aatatttaaa atatattcat atttttctat tttatctaaa tgcgattttc atatctaata
      661 atagaaaaat aaacaattaa caataaaaaa gtcttcattt attgtt
//
LOCUS       DAFEML010000182          703 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFEML010000182
VERSION     DAFEML010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.190"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..582)
                     /locus_tag="LP468_002788"
     CDS             complement(<1..582)
                     /locus_tag="LP468_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082230.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYK"
BASE COUNT          229 a          119 c           72 g          283 t
ORIGIN      
        1 tttgtaaaaa tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat
       61 gtcaatattt ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa
      121 ttccctgtaa ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc
      181 acccattcca ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc
      241 agtttgttta tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc
      301 aaaaattttt tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac
      361 tgataattga tactctatat tacatgactt aattagtttt ttagatcccc cctccagata
      421 ggcatatgtt tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc
      481 ataaattaaa aatgactgtc tatttagccc ataatctaat acaacttctt catactcata
      541 tttctttaaa tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt
      601 gttatttatt gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt
      661 agtgaactac tcaccactta gctaaaccta acggtttctt acg
//
LOCUS       DAFEML010000183          674 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFEML010000183
VERSION     DAFEML010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.191"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..465
                     /locus_tag="LP468_002789"
     CDS             <1..465
                     /locus_tag="LP468_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082231.1"
                     /translation="TQNNDQLVSGNFTLKGEGQLTFYLLPTIAEMKTAIRRKDKIQPT
                     VTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSERDSPSRILKRIKFPPYLEQI
                     VVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLHANKRPKKIAATKK"
     gene            480..>674
                     /locus_tag="LP468_002790"
     CDS             480..>674
                     /locus_tag="LP468_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL2082232.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYC"
BASE COUNT          220 a          134 c          138 g          182 t
ORIGIN      
        1 actcaaaaca atgatcaact ggtatctggc aacttcacac taaaaggtga aggacagttg
       61 actttctatc tattgccgac gatagctgaa atgaaaacag caattcgccg caaagacaaa
      121 atccaaccaa ccgtgacaat gagcagaaaa acatctgata agattcaagg tgtggctttt
      181 tatggccatt atctcttagc cagtcgttct tatggtcctt atacctcgga actcttagtg
      241 tccgagcggg actctcctag ccggatccta aaacgaatca aatttccacc gtatttggaa
      301 caaatcgttg ttgtagaaga tcgtctagca gtattgtttg aaagtggcgc cgcagcgtat
      361 cgcgagaaag ccaatcctgt gttagccaat gttttattac tagacttagc aacgttgctt
      421 catgcaaata agcgtcccaa aaagattgct gcaactaaaa aatagtcgga caactcaaga
      481 tgatcactgt tgttcataaa gaacgacaag aaaaatcatc tagcgatgtt cgactatggg
      541 tttatttagg aagtatttct actaagattc aatatggcta tacagattcg gcgaaaaaac
      601 aaggcaatgt taagtttttg agaatcacag atatacaaga gggacgtgta aattggtcca
      661 gtgtgcctta ctgt
//
LOCUS       DAFEML010000184          599 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFEML010000184
VERSION     DAFEML010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.192"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(310..>599)
                     /locus_tag="LP468_002791"
     CDS             complement(310..>599)
                     /locus_tag="LP468_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082233.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          207 a           98 c           90 g          204 t
ORIGIN      
        1 attgtgagat gataataaag aagagtttaa agcgcacccc aagccacttc cccataagtg
       61 tgttacgctt taaactcttt tatatttgaa gctattaaaa ggcataccat atttttgaaa
      121 aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt
      181 ttatagcact gatactataa aatatagata tcatcatatt acacaatctt aatactaact
      241 taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg
      301 tagcctactt taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata
      361 acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca aaaagtatac
      421 atccttcttc attctagttt tcgcagcagg aattttgaaa tagttcttat tagaatagta
      481 gagattgatt aataagctat cttcgattgc taaaaagaaa acttctgaat tccatacttt
      541 ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt gtgtctcat
//
LOCUS       DAFEML010000185          574 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFEML010000185
VERSION     DAFEML010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.194"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..572
                     /locus_tag="LP468_002792"
     CDS             <1..572
                     /locus_tag="LP468_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL2082234.1"
                     /translation="IRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIK
                     GRKIYLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQY
                     QMPQYQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLN
                     EYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          248 a           71 c           94 g          161 t
ORIGIN      
        1 aaatccgaat aaagcgatat aaatcttata aaggaacagt aggaaaaatt gccaagaatg
       61 tgttaaaacg aaatttttca gtagatacac ccaataaaaa atgggtgaca gacgtcactg
      121 aattcaagat aaaaggaaga aaaatctatc tatctcctat acttgattta tttaacggag
      181 aaataattag ttatagtata tcaactagtc caacatataa actgattgaa gaaatgcttc
      241 aacaagcaat taaaaaaaag ggaactgagg gttcactgat tctacattca gatcaaggat
      301 ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga gaataacatt attcaaagca
      361 tgtctagaaa aggaaattgc ttagataatt ctgtaataga aaattttttt ggtgtgctta
      421 aatcagagtt tttttatcga gaaaaattcc gatcaattga gatatttcaa agtaaattaa
      481 atgagtatat taggtggtat aataacaaaa ggataaaact aaagttaaat ggactatctc
      541 cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAFEML010000186          570 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFEML010000186
VERSION     DAFEML010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.195"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..>570
                     /locus_tag="LP468_002793"
     CDS             <1..>570
                     /locus_tag="LP468_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBL2082235.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKL
                     ALKGITISVPPRKNMDKSEKLDHSLLGKQ"
BASE COUNT          195 a          110 c           99 g          166 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaatc catgaaaagc
      481 ttgcccttaa gggcattact atatccgttc cgccacgtaa aaacatggat aaatcagaaa
      541 aactagacca cagcttactt ggaaaacaaa
//
LOCUS       DAFEML010000187          557 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFEML010000187
VERSION     DAFEML010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.196"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            <1..>557
                     /locus_tag="LP468_002794"
     CDS             <1..>557
                     /locus_tag="LP468_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2082236.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEK
                     VMNQRTDFLNKLSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYK
                     ADWYGRKIIKVDKWFPSSQICSNCG"
BASE COUNT          205 a           88 c           97 g          167 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tattatattt ctttgttatg caaagaagaa
       61 gttcgcgaac tacctaaatc taattctgct gttggtattg acctaggtat tatagacttt
      121 gcaattcttt ctaccggtca aaaatttgat aataataaat ttacgtccaa aatggaaaag
      181 aaactcaaac gtgaacaacg taagttgtca agacgtgcct tattagctaa acaaaaaggt
      241 atcaatctgt ttgaagctag aaattatcaa acacaaaaac gtaaagtagc acgattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aattatcaaa
      361 aatcacgata tcatctgtat tgaagactta aacacaaaag gcatgttgcg taatcataaa
      421 ctagcaaaaa gtatttcgga tgtttcttgg tctagttttg tgtctaaatt acaatacaag
      481 gctgactggt acggtcggaa aatcatcaaa gtagataagt ggtttccatc tagccaaatc
      541 tgttcgaatt gtggaca
//
LOCUS       DAFEML010000188          556 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFEML010000188
VERSION     DAFEML010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.197"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            70..>556
                     /locus_tag="LP468_002795"
     CDS             70..>556
                     /locus_tag="LP468_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBL2082237.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FM"
BASE COUNT          208 a          101 c           92 g          155 t
ORIGIN      
        1 acaaaaaagg aagtcccttc tgtagaataa agttaacgac aaccaattca cagaaaagag
       61 gacttcccta tgaatgattt tactacagaa attgtgcaaa ctctagtcac taaaggcgat
      121 ttaaatgaat tattccgttc gcacttagaa aaagcgataa acacactcct acggactgaa
      181 ttaacggctt ttttagatta cgaaaaatat gatcgcactg gttttaattc aggtaattcg
      241 agaaacggtt cttactttcg atcaatcaaa accgaatatg gtgaattaac attggaaata
      301 cctagagatc gtaatggtga gtttaaacaa caaactttac cagcctacaa aagaacaaac
      361 gatacattgg aaaccactat tatccattta ttcgaaaaag gtgttacgat gtctgaaatt
      421 gctgatttga tcgaaaaaat gtacggtcat cactatactc cacaaaccat gtccaacatg
      481 actaaagttc tgactgaaga agtaaatgcc tttaaatcca gagccttaaa tgataagtat
      541 gtcgctattt ttatgg
//
LOCUS       DAFEML010000189          552 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFEML010000189
VERSION     DAFEML010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.denovo.198"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            92..>552
                     /locus_tag="LP468_002796"
     CDS             92..>552
                     /locus_tag="LP468_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL2082238.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRP"
BASE COUNT          175 a          109 c          100 g          168 t
ORIGIN      
        1 accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta
       61 atttggctac caattcatag gaggattcaa gatgtctcat actcagctta tcaaagatac
      121 cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta aagaaaaata
      181 caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag aagagtgttc
      241 ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa ccgttcggtt
      301 gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac aacgatttaa
      361 atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa aacactgttt
      421 cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata cttccatgac
      481 ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca tgaagcgatt
      541 ctaccgccca tt
//
LOCUS       DAFEML010000190        20985 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.041, whole genome shotgun sequence.
ACCESSION   DAFEML010000190
VERSION     DAFEML010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.041"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(134..577)
                     /locus_tag="LP468_002797"
     CDS             complement(134..577)
                     /locus_tag="LP468_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2082239.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="LP468_002798"
     CDS             complement(795..2135)
                     /locus_tag="LP468_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2082240.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="LP468_002799"
     CDS             2404..3300
                     /locus_tag="LP468_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2082241.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="LP468_002800"
     CDS             complement(3450..4391)
                     /locus_tag="LP468_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2082242.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="LP468_002801"
     CDS             4517..5638
                     /locus_tag="LP468_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2082243.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="LP468_002802"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="LP468_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2082244.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="LP468_002803"
     CDS             7426..7992
                     /locus_tag="LP468_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2082245.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="LP468_002804"
     CDS             8203..9264
                     /locus_tag="LP468_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2082246.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="LP468_002805"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="LP468_002805"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2082247.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="LP468_002806"
     CDS             10177..12159
                     /locus_tag="LP468_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2082248.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="LP468_002807"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="LP468_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL2082249.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="LP468_002808"
     CDS             12881..14305
                     /locus_tag="LP468_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2082250.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="LP468_002809"
     CDS             complement(14486..15259)
                     /locus_tag="LP468_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2082251.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="LP468_002810"
     CDS             complement(15256..16161)
                     /locus_tag="LP468_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2082252.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIETIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="LP468_002811"
     CDS             complement(16315..16635)
                     /locus_tag="LP468_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL2082253.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="LP468_002812"
     CDS             17109..17795
                     /locus_tag="LP468_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL2082254.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="LP468_002813"
     CDS             17797..18741
                     /locus_tag="LP468_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL2082255.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="LP468_002814"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="LP468_002814"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL2082256.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="LP468_002815"
     CDS             19663..20940
                     /locus_tag="LP468_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2082257.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6778 a         3784 c         4361 g         6062 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcgt tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tttcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcacta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DAFEML010000191        13213 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.064, whole genome shotgun sequence.
ACCESSION   DAFEML010000191
VERSION     DAFEML010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.064"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            complement(204..2162)
                     /locus_tag="LP468_002816"
     CDS             complement(204..2162)
                     /locus_tag="LP468_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2082258.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="LP468_002817"
     CDS             complement(2159..3031)
                     /locus_tag="LP468_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2082259.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="LP468_002818"
     CDS             complement(3373..4245)
                     /locus_tag="LP468_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2082260.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="LP468_002819"
     CDS             4373..4942
                     /locus_tag="LP468_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2082261.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="LP468_002820"
     CDS             5009..5746
                     /locus_tag="LP468_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2082262.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="LP468_002821"
     CDS             5977..7245
                     /locus_tag="LP468_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2082263.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="LP468_002822"
     CDS             7732..8196
                     /locus_tag="LP468_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2082264.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="LP468_002823"
     CDS             8180..8809
                     /locus_tag="LP468_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2082265.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP468_002824"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP468_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2082266.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="LP468_002825"
     CDS             10688..11134
                     /locus_tag="LP468_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2082267.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="LP468_002826"
     CDS             complement(11333..11848)
                     /locus_tag="LP468_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2082268.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="LP468_002827"
     CDS             11965..13167
                     /locus_tag="LP468_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2082269.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAFEML010000192         7780 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.089, whole genome shotgun sequence.
ACCESSION   DAFEML010000192
VERSION     DAFEML010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.089"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            245..1213
                     /locus_tag="LP468_002828"
     CDS             245..1213
                     /locus_tag="LP468_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2082270.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="LP468_002829"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="LP468_002829"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2082271.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="LP468_002830"
     CDS             2243..2851
                     /locus_tag="LP468_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2082272.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /locus_tag="LP468_002831"
     CDS             3279..4190
                     /locus_tag="LP468_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL2082273.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4343..4828
                     /gene="vanZ"
                     /locus_tag="LP468_002832"
     CDS             4343..4828
                     /gene="vanZ"
                     /locus_tag="LP468_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2082274.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5115..5444)
                     /locus_tag="LP468_002833"
     CDS             complement(5115..5444)
                     /locus_tag="LP468_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2082275.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5749..6078
                     /locus_tag="LP468_002834"
     CDS             5749..6078
                     /locus_tag="LP468_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2082276.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6068..6355
                     /locus_tag="LP468_002835"
     CDS             6068..6355
                     /locus_tag="LP468_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2082277.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6634..7197)
                     /locus_tag="LP468_002836"
     CDS             complement(6634..7197)
                     /locus_tag="LP468_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2082278.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2566 a         1298 c         1546 g         2370 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacca tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc tagctttata
     4381 tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt tatcagtatt
     4441 taattatcat caaagaagtc ttaacttgac tccatttact gctactggga atttcagaga
     4501 gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg tcaattttaa
     4561 agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta cttttgaaat
     4621 aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta caaatactgt
     4681 tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga atcaaaaaaa
     4741 attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc tcgtttaccg
     4801 tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg atctttcata
     4861 cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg aaactcgccc
     4921 gtaggtgtga agtgagggga aaaccggtga taaagtaaaa agcttaccta acactatagt
     4981 aacaaagaaa gcccaattat caattttagt gctgaggaat tggtctcttt aataaatttc
     5041 cttaacgttg taaatccgca ttttcctgac ggtaccccca aactaagatt tcatagatag
     5101 attttctgat aactttaaaa aacacgaata gcggaaagga tgtcttcatt cgctaaagag
     5161 taataaacta cttttccatc ttgacgtgat tttgccattc catgtttttt taaaaaacgt
     5221 aaatggtgtg acgttgtagc gacactagca gtaagtattt ctgctaaatc acagacgcac
     5281 atttccttat aggtttctaa agcatagaaa attttaattc tagaaaaatc gctgaaacat
     5341 ttccctaaca caagtaagtt tgaaaaatct ttttgatcca atttattttt tattccattt
     5401 actttttctt tatgtacgac agtcacttgg caaacttttt tcattcatct cacctcacat
     5461 tcaaacgatt atttgaatga agtataccta tttgatcact cttttgtcaa tctaccttaa
     5521 ttccaataca ctattataag caatttcatg tattgaagta aacttacttg caagtgcgtt
     5581 tttgattcca agttaaaaac atattattat tctacataat ttcctaatca aataaaactc
     5641 ctttgaaaat tgttctaaag gagttttatt attttgtatt tctactaaaa atagcgtaca
     5701 atgtaattac taagtaatta cgaaatgtaa aataatggag gaaataatat gattacaaaa
     5761 acaagaaaac aaggaaattc tattatgtta acggtcccta aagaattcga tgtgcccaat
     5821 ggtgttgaag tagaagctaa gcttgtagag aatggtatcc tttatgagtt tgtagagcct
     5881 aaaaaagaat tttttgattt tagtgaagat attttggctg atattctttc agaaggttat
     5941 agcaaacaag agatcttaaa agaatttaga aatagaaaaa atgcgttaac ttctgcattt
     6001 aaatctattg ctgaagatac tgttgcaaat tctaaaccga tgacaaaaga ggagttggca
     6061 gcagaaattg gcttatgaga ttctaccttc taaacacgta ataaagtatc taaaaaaatt
     6121 aaaagagaaa acattaaaag aacaattttt aacgataatt tatgatgaga tagcagttcg
     6181 tcctcattcg ggagaacaaa aaacgggtga tttatcagga atttgggcta ttggattcaa
     6241 gtatgcaggt acgacatatc gcgttgcata tgaaattaaa gataatgcag tgatacctat
     6301 cttactatgt ggaacgcatg aaaattttta tgaacaatta aaaaagatta ggtaagaacc
     6361 caatgtttca acttgagagg atagacgaca ctttaaaaga taatttttaa cagctgagag
     6421 ttgtaatacc ctataatttt aaaccactaa cctatatatt tatgaaaaat agaaaaaatt
     6481 aaaacgcatt ttaagcctct ttcaaattaa aagcttcatc cttatgcaca aagagggctt
     6541 aaaatgcgtt attttatatt gttttttagt aataataaaa aaatcactct aattctccca
     6601 taaatattat agattcctaa agattaaaat agattattcc ctattgtctt ttaagtagcg
     6661 gtagagtgtt gccttgctaa taccagtcat ttccgtaatt tcttttacgc tataaacctg
     6721 acttttatac aattttactg ctcgatcaac atctttctgg ttcactcgtg gacggccacc
     6781 tttacgacct ctcgcacgtg cacttttcaa accttctttg gtacgttcaa caattaaatc
     6841 acgttcgaac tgactaaatg cttggaagac agtcatcatt aagcgtccgt gaggcgtgct
     6901 ggtatcgaag ttttctttca agctcaccag cttaacatgg tgttcttcaa aataggtaac
     6961 aaggtcaatc aaatcctttg tactacgacc caatcgagaa aaactttcta caattaccgt
     7021 atctcccgga cgaattttat cttttaaacg atttagttgg ggacgaaccg ctttggttcc
     7081 cgtcattttc tcagttagga tttcattaca attttgttca ttgagtaagt ctaattgacg
     7141 atttagttct tgtgaacgtg tactcactcg ggcataacca taaatgtatc cactcatgct
     7201 tttcttcctt tcgtacttta attctggctt gattgtatca taaaagggag ttatagatac
     7261 atagttaatg caacaagtta tgatacaaaa tatgacctct tttatttaat aaaagaggtc
     7321 atttcatttt gtctcataat cgattgtttt tgatacgagt gtgtatacga aataaacaaa
     7381 aaaatcttaa gtaaatttct agatacctaa tttaatccta actagtgtat cctaaagtta
     7441 ataacgagtt tatcacaatg aaaattataa aatgctccca tattagatat aacatgcaat
     7501 atttgaatta gaactacaaa atttattcgt tttataaagt aaataatgtt gagatactaa
     7561 ggaatagaat attataagga attgagctga atgtattgga taaaaaaaga ataactttat
     7621 tagagatgga ctataaaaat gctcgtaatt ttcttctgaa gtctgaaagc tatttgaatg
     7681 ctcagctacc agaatatatt agttttgacg aaactttaaa atctgctaaa aaagttttaa
     7741 cttcgccgtt tgtataatta agcgagacaa ataaaaaagc
//
LOCUS       DAFEML010000193         4513 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.122, whole genome shotgun sequence.
ACCESSION   DAFEML010000193
VERSION     DAFEML010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.122"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            309..1522
                     /locus_tag="LP468_002837"
                     /pseudo
     CDS             309..1522
                     /locus_tag="LP468_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            1553..1771
                     /locus_tag="LP468_002838"
                     /pseudo
     CDS             1553..1771
                     /locus_tag="LP468_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2190..2663
                     /gene="dfrF"
                     /locus_tag="LP468_002839"
     CDS             2190..2663
                     /gene="dfrF"
                     /locus_tag="LP468_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL2082279.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2790..3446
                     /locus_tag="LP468_002840"
     CDS             2790..3446
                     /locus_tag="LP468_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL2082280.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3628..4158
                     /locus_tag="LP468_002841"
     CDS             3628..4158
                     /locus_tag="LP468_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2082281.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1510 a          663 c          955 g         1385 t
ORIGIN      
        1 gaacaaattt gagaaccgta gcgacactcg ctgcggttct tttttatata ttttatatga
       61 agtattcttt attccttatg aaaaaatatc tttaaaaata aaaaaagacg aaaataaacg
      121 gttttctata aaaagaagac cgtttatttt ttgtctttat ttgtgtgaaa aacgaaaaag
      181 agcacaacac atcaagcttt tattaattgt ctgtctttta taaatgcaag tattaattca
      241 aaaaaacaga agaaaaaaac aactacacct tcttttatac tcgtaatcgt agaaaggagg
      301 cgaaaaaaat gaatacatta cctatcaata caggagatac agcattcatg attttatgta
      361 cagcaatggt ttgcctgatg actcctggtc tagctttttt ttacgcggat tagcacggaa
      421 gaataatata ctaacgatca tgtctcaatc ttttctctcc gttgggataa caacgattat
      481 gtgggtattt ggtggattcg gattggcctt tggacgggat atcggcggtg ttattggaaa
      541 cccggcagat ttctttttga tgagacatgt tacaagcttc cccaacatgt ttcatggtgc
      601 aacgattcca tttttaatgt tctttcttta ccaactgatg tttatcgtga ttaccgttcc
      661 tttgatgaca ggagcttttg cagggagatt gaatttaaaa ggctatatta tacttgttat
      721 tttttggaat ctgctgattt atttccctgt ttgccactgg atatggggtg gcggattttt
      781 ggatcagatg ggatttagag atttcgctgg tggagcagtc atccacacga cagctggatt
      841 cggctcttta gcatgtatcc tcacacttgg tcaaagaaag attcctttag gagaaagaag
      901 tcagcatagc agtcttatgg cagctgctat cggtacagga ctgctttggt ttggctggtt
      961 cggttttaat tccggtggtg cacttcgagc agatgaacaa gcagtcaatg catttggttc
     1021 aacattcatc gctcttgcat ttgcgatgat tacttggctg atcattgcaa aagtaaaagg
     1081 aaatggcttt gattttgtcg acgtactaac aggatccgtt gctggattgg cagccattac
     1141 gccttgtgcc ggttatgtag aagcaaaaag tgccatgctg attgggatca ttgcgggtat
     1201 cgtctgtcat gctgctgttg attttcgtaa aaagaaacaa tgggatgatg cacttgatgt
     1261 gtggggtgtt catggcatgg gcggattcac aggtacgatt ctgataggga tctttgcatc
     1321 taacagccat ttactaacga atccaagcag ctggtacttc ttagggattc aagtgattgg
     1381 tgtcatcatt actgccgtgt atgcctatgt gctgacaaca gtgattttaa aatcggcgat
     1441 gcactttaca acgatcacta ctacaaaaga agaacaagaa gaaggattgg actttttctt
     1501 ctttggcaac aaactcaatt gaaacaaatt caaatagaaa agaggaagat tcatgcaaca
     1561 aagcaaaacg aaaattcctg caaaaaaatt aacgttcttt ggctttttgg ctatgaccat
     1621 ctcaatggtc gtttcattat atgaatatcc cacattcgcg acctcaggct tcagcttagt
     1681 atttttcttg ttattaggcg gtttgctatg gtttatccct gtggcattgt gcgcagcaga
     1741 gatggcaacg gtgaaaggat gggaaaaagg tgtttcccaa acaaaaagat attaagaaac
     1801 agcccatgtt tacctgcttg caaacaaaag aatattgcta ctagactaag agatactaca
     1861 taagtgtgtt ggtatctctt ttttgttgcc gtgaaacagc agactatttc atttctgctt
     1921 gattacctta aaacttatta gtctatggtt tgtcaagggc ttgttgcgtg agaaatgctg
     1981 aatatcaccc tttacaaaac ataggctgat aagtaacttt tcaaaagcag aaaagaaatg
     2041 gcaatgctta taacaatatg atataatgca gatgaagaca aaaaaggaat ttgtcgagct
     2101 ggttagttcg agataatttt gagtttgtta agatgtggtg cacttgatgg aatcacaggt
     2161 acgacatcat attatggagg atgaaataga tgataggttt gattgttgcg aggtcaaaga
     2221 ataatgttat aggcaagaat ggtaatatac catggaaaat aaagggagaa caaaagcaat
     2281 ttagagagtt aacaacgggt aatgtggtta ttatggggcg aaagtcttat gaagaaatcg
     2341 gtcatccgtt gcctaataga atgaatattg ttgtttccac cacaacagag tatcaaggag
     2401 ataatttagt ttcagttaaa tcattagaag atgcattatt attggctaaa ggacgagatg
     2461 tatacatatc tggtggatat ggactattta aggaagcttt gcaaatagta gataaaatgt
     2521 atatcacaga agtagattta aatattgaag atggagatac attctttcca gaatttgata
     2581 tcaatgattt tgaagttttg ataggggaaa cacttggtga ggaagtgaaa tatacgagaa
     2641 cattttatgt aaggaaaaaa tgaattgagt aaattttgga tttagggtgt tttcataaat
     2701 atattgcttt ttatgcatat ataaattgtt gtaagacaaa ttccagtttg tatggggcga
     2761 taaaatcaga atttgagaga ggattgaata tgaataagga atggtctgaa cttaataaaa
     2821 caatgcaggc acaaataaaa aagaaagata cttataagag gggtattgat actttactta
     2881 ctttacgaag tcagttaata caaaccttag tatctttcaa agaagaatta tgcagagaag
     2941 attttaactc aatccccttc ataaacgctg atggttatca tagtaagacg attgcttatt
     3001 ctatttggca tattttccgc attgaagata tagttgtgca tacagtgata aatgaagatg
     3061 aacaagtatt ttttgcaggc aattatcaag agcgtatcaa ttcacctatc attacaacag
     3121 gaaatgaact catgaaacag cagattgcag acttttcaaa acagcttaat ctggaagaat
     3181 tatatttata tattttcgaa gtatgggaaa gcactgagaa aatgcttgaa cggttatctt
     3241 atgatgaatt gaaaagaaaa ataccgaaag aaagaaaagg atacttagaa tcgttgaatg
     3301 tagtaaacga caatgaaaaa gcaatttggc tgattgatta ttggtgtaat aaagatattt
     3361 gtggactaat tcaaatgccg ttttcaagac attggattat gcacacagaa gcctgtttgc
     3421 gtataaagaa caagatacat tcataggcaa aaatttcagt ttgtagaact aaggaaattg
     3481 gaatttaagg aggaataaag tatggttagt gattttataa gagcagcatt tccatggatt
     3541 ttaatgggtt tatttgtagc aatcagttgt tcccttatga gtaaaaaaga gaaataaatt
     3601 cctgtttgta tttataaaag agaaaaaatg agaaaagtag ttttatttat tgccatgagc
     3661 cttgacggat atattgcgga cggtaatggt ggagtagctt ggctaaatgg tcatggaaat
     3721 gacaatgaaa acatcgacac ttatacagaa tttaccaaag atatagatac tgtcttaatg
     3781 gggtggaata cttctcatca ggttgttact gaactttctc cgcaagaatg ggtatataat
     3841 aaatttacaa cttatgtatt aacacataaa gagtgcaatt cttcccaaca aattcatttt
     3901 acaagtgaaa atcctgtttt attattggaa cggctaaaac aagaagcagg aaaggatatt
     3961 tggatttgtg gcggagcaaa tcttgttcag cagttggtaa gcaaaaatat gattgataaa
     4021 tattacattt ctgttattcc tactctgtta ggaaatgggg ttcgtctttt gggcaacata
     4081 gacagggaaa taaagttaag gctttgtaaa acacagactt ataacggaat aaccgatttg
     4141 atttatatgc gtagataact agagagaaac agaaaagctg ttaaaccgac ggagcgatcc
     4201 gaccacgttg gcgggaaaat ccttaagatt tttccgccat gcttgcaagg gggcggttcg
     4261 cttcggcggt tcggcgagct tgcgagccgt tcaaagcccc cgttatctaa caaggggggc
     4321 acaaaaaaca agaaacacta tacactaaca agcggaaaac gctgtattta taaggcaaaa
     4381 ccccattttt acagtagtga tataaattgt acctatatca ctatgaaaat tgaatagtaa
     4441 atatgagaaa gacagttgat ttcaaaaaat aagaaaggct ctttgtcaat aaggactgat
     4501 gagttgtgca aaa
//
LOCUS       DAFEML010000194         4430 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.124, whole genome shotgun sequence.
ACCESSION   DAFEML010000194
VERSION     DAFEML010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.124"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            35..280
                     /locus_tag="LP468_002842"
     CDS             35..280
                     /locus_tag="LP468_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2082282.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            383..1252
                     /locus_tag="LP468_002843"
     CDS             383..1252
                     /locus_tag="LP468_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2082283.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1233..1967
                     /locus_tag="LP468_002844"
     CDS             1233..1967
                     /locus_tag="LP468_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2082284.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2000..2908
                     /locus_tag="LP468_002845"
     CDS             2000..2908
                     /locus_tag="LP468_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBL2082285.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2905..3447
                     /gene="sat4"
                     /locus_tag="LP468_002846"
     CDS             2905..3447
                     /gene="sat4"
                     /locus_tag="LP468_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL2082286.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            3540..4334
                     /locus_tag="LP468_002847"
                     /note="aph(3')-IIIa"
     CDS             3540..4334
                     /locus_tag="LP468_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2082287.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         1521 a          641 c         1010 g         1258 t
ORIGIN      
        1 ggggctgacc cattattaat aaggagtgga caacatgatt gatgtaaatg agctattgga
       61 agaagctatt agagaaactg aaaatctaaa tgatggcgaa gtttttcttg ttaaagattt
      121 attcaaggga tatgtgggga ataggatacc cagaaaggat cgacttctgc ttggaacgtt
      181 atttttaaac catgttagca aaatgaatgg taatttaaag gctattgaaa agacttcatc
      241 taatcagcag aggtataaaa agacaattga taagttttaa ctatcttttg tgaaattaaa
      301 aaaattataa atatgttgag tagaagcaaa agatttggct tggaattttt acagcagtga
      361 atcgataaaa ggagcatgct tgatggtaga taatattatt aaatcagtag cagagaaatt
      421 atcctctctg tcttatatag aaggtattgt tttaggtggt tcacgtgcaa ggggcaccca
      481 tacagaggat tcggatatag atatcggcat ctattacaat tcagaatcat ttgacataaa
      541 tactattaat caattcgcta caaagctgga tgatgagcat agaaataacc ttgttgtacc
      601 tcccggagca tggggtgatt ggattaatgg cggcggatgg ttagtcataa acgggtatca
      661 tgtggattta attttacgtg atattaaacg tgtggaacaa ataatgaaag atacagagca
      721 cggaattgtt actgccaatt atcagactgg gcatccccat ggttatatta gtgcaatgta
      781 tcgaggagaa ttagcgatta gcaaaatact atatgctaag aatgaaagct tatgcgaatt
      841 aaaaaaacag gcagaaactt atcccaatgc tttgcagaaa agtttagtta acttttttat
      901 gtttgaagca gggttctctt taatgtttgt aaaagcaaat tcgggaacag acgataaata
      961 ttatattgcg ggtcatgttt ttcgtatagt ttcatgttta aatcaagtgt tatttgcatg
     1021 taataatgct tattgtatca acgaaaagaa agctataaaa ctgcttgaaa cttttgaaca
     1081 taaacctgaa aaatataccg agaaggtaaa tcatattttt gaagtactcg gtatctcact
     1141 ttttgaatgc tacgacatga ccgagaagct ttataatgaa gtgaatgaaa ttgtatcgga
     1201 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1261 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1321 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1381 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1441 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1501 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1561 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1621 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1681 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1741 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1801 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1861 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1921 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1981 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     2041 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     2101 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     2161 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2221 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2281 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2341 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2401 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2461 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2521 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2581 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2641 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2701 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2761 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2821 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2881 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2941 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     3001 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     3061 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     3121 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     3181 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     3241 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     3301 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     3361 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     3421 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     3481 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     3541 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     3601 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     3661 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     3721 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     3781 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     3841 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     3901 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgattag
     3961 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     4021 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     4081 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     4141 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     4201 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     4261 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     4321 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     4381 acatctaatc ttttctggct ctttgtcaaa tgatgttggt aaagagaaat
//
LOCUS       DAFEML010000195         3824 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.131, whole genome shotgun sequence.
ACCESSION   DAFEML010000195
VERSION     DAFEML010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.131"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            193..1260
                     /gene="rlmN"
                     /locus_tag="LP468_002848"
     CDS             193..1260
                     /gene="rlmN"
                     /locus_tag="LP468_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2082288.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(1453..2556)
                     /locus_tag="LP468_002849"
     CDS             complement(1453..2556)
                     /locus_tag="LP468_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2082289.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            3109..3657
                     /gene="aac(6')"
                     /locus_tag="LP468_002850"
     CDS             3109..3657
                     /gene="aac(6')"
                     /locus_tag="LP468_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2082290.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         1247 a          651 c          768 g         1158 t
ORIGIN      
        1 tgctggtgtc atccaccaac atcaaaaagt atagagccgt ttttttccat cttttctaat
       61 acggtatgat gtcttgtctt tttagttttt gtgagattaa agttctattc gatttatttg
      121 tgaagtattg cattaaggaa atgaatcatg tatagtatgt agcgaaactt tgagaaaaag
      181 agggaaaata ctttggaaaa acagtccatt tatggcttga cgaatgaaga attaatcaat
      241 tggtttatag aaaacggcga gaaaaaattc cgagctgccc aagtttggga atggttgtat
      301 caaaaacgtg taagtaattt cacagaaatg acgaatctat cgaaacaatt gatcgaaaaa
      361 ttatcggagc attttatcat caatcctcta aaacagatgg tcgtccaaga agcttcggat
      421 ggtacagtaa aatatttgtt tgaactccct gataaaaaca tgattgagac tgtactgatg
      481 agacaagaat atggcttgtc agtttgtgtg acgacacaag taggatgtaa tatcggctgt
      541 acgttttgtg caagcgggct gctcaaaaag aaccgtgatc tgactgctgg agaaattgtt
      601 gcacagatca tgatggtcca acattatttt gatgagcgca atcttggcga acgcgtttca
      661 catgtcgttg taatggggat cggtgagcca tttgataatt acgacaatgt aatggacttt
      721 ttgcatatca tcaatgatgc caaaggattg gcaattggtg ctcggcacat tacagtttcc
      781 actagtggat tagcacacaa aatcaaggaa ttcgctaata acggcttgca agtcaatctg
      841 gctatttcct tgcacgcgcc gaataatgag gtgcgaacat cgatcatgcg gatcaaccga
      901 agtttcccaa ttgagaaatt gatggaagct gtggatgagt atttagagaa aacaaaccgt
      961 cgaatcacgt ttgaatatat catgttgaat caagtaaatg atagaccaga gcatgcgcaa
     1021 caattagcag atctattaaa agataagaaa aaattagcat atgtcaactt gattccatat
     1081 aatccagtca gtgaacatga tcaatattct cgcagtccaa aagctgatgt attgagattt
     1141 tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac gtaaagaaca tggtacagat
     1201 attgatgcag cttgcggaca attgcgaagc aagcaaatga aaaaaacagt tgccaaataa
     1261 tcgtatccta ctcgtttttt caattaccat aaaaggagca gttttcttaa ttaaggaact
     1321 gttcaactta aataagagaa aagattctat agcgaaagct ataaagcttt ttttgacaag
     1381 aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg acagcctgct tgatgggggt
     1441 tttagcaatt atttaactga ttttcttata tccttgctgg ctttcttgtg tagcatgata
     1501 agtttctacg tcaagaatgg cctgtttaaa tttttctcgg gtgatttcat aaggcacatg
     1561 tttaatatca tttgttgcca tggctttatc taagattgct tctaaatcgg tcgtgacatt
     1621 gagattcatg tcggttaacg atactggaag ttggttcttt ttcataaaca catagatttt
     1681 atcaaacaaa tcgaactgct gatccatcat caataaggtc agtacaccat aactgacaga
     1741 tgctccgtga aggtatccct ccattttttc tagaacagtc gtaccgtaat agaatgagtg
     1801 tgccatagca gaattatagt tattgttaac taaaacagaa accaatccgg tagtaacaat
     1861 gatatccgaa acgacttgtt caattgcata tgagggacga tcgtcggcac tatctttcaa
     1921 tgcttgcgta ccataagtca agagacgatc aatgcacatt tttccgattt ggattcctaa
     1981 tctatccgtg tagcctagat catcgccacg agcagaaaaa gtagattcga cttctttgga
     2041 taaagcatcg ccaatacctg cccataagta tttatcaggt gcttcggcaa taattgctgt
     2101 atcaatgaag gtgtgtacag gtggttttga aggaaagaag agtccgtcca ttacgccttc
     2161 ttcgttatag atgacacata ccgcagtgac gggcgaacag ttcgaaccaa tagtgggaaa
     2221 ggtgaagact ggtttagcta gtttttcacc aatgactttt acagtatcgc aagcacggcc
     2281 accaccgact gcaaacagga cgtctgcttt ttggacactt tcatgctgga tcaactgttc
     2341 aatatttcca taagttgaat tacccccgta ccagagactg gcgacaacct ctatttcctg
     2401 tgtcaaagct acttttattt tgttttctgc ctttgaaagt gcagtcttcc ctccaatcag
     2461 cactactttt gtcccatatt ctttgacgat tccatttgct ttttcatacg catctgttcc
     2521 aatggtataa tttggtaaga aaacactttg actcatattc atttccttct ttcttcgttg
     2581 aaacgggtta aaattttaaa gagtgatcga tctgactgcg gctgtagatg gagtagaggt
     2641 gaacctaaga caggataagt gatgaataag gtggcatgaa caccttgaaa tcatcaataa
     2701 gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga caataatgaa tttttgttcc
     2761 tcttagtatt tctaccgatt ccctttgctt ttttgtaatt atctaaaaat tctaaaaatt
     2821 aagattatta tatgaaaaca ggttttattt gtcaattcat aattggtttt ttttaaagca
     2881 aaagataatc tatatcatga tgaacaaaca gagttttttc ctccaattga tggctttcct
     2941 gatctttcct attttgaata aagtgtttct gtataatttt tttattttat aagtaagata
     3001 aataatgaaa gaatagagat actgattggt agctaaagat ttttgagcga gaacatttcg
     3061 ttttttcaaa aggactgtta gaataagcaa gaacaagggg gaagacgtat gataatcagt
     3121 gaatttgacc gtaataatcc agtattgaaa gatcagcttt ctgatttact gagactgact
     3181 tggccggaag aatatggaga cagctcggca gaagaagtag aagaaatgat gaatccagaa
     3241 cgaatcgcgg tagcagcggt agaccaagat gagttagtag gatttattgg tgcaatccct
     3301 caatacggta tcacaggttg ggaattgcat ccattagttg tagaaagctc ccgacgaaag
     3361 aaccaaatag gtactcgatt agtcaattac ttagaaaaag aagtagcttc cagaggagga
     3421 atcacgattt atttaggtac ggatgattta gaccatggaa caacgttaag tcaaacggac
     3481 ctgtatgagc atacatttga taaagtggct tccatccaga accttcgtga acatccgtat
     3541 gaattctatg aaaaattagg ttataaaatc gtaggtgtct taccaaatgc aaatggctgg
     3601 gacaaaccgg atatttggat ggcaaaaacg attattcctc gaccaaattc tcaataataa
     3661 aaagaggttg tgacagaagt aatcagcttc aagaaataag aaggaattta cgaaaattac
     3721 ttcttgaatt tttgtgaaat tccaacttat ttccgaagaa gctacttttg gaacaccgtg
     3781 taccagaggt tgtgaaaaag tcgcttagtt tcgagtagta agaa
//
LOCUS       DAFEML010000196         2224 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.148, whole genome shotgun sequence.
ACCESSION   DAFEML010000196
VERSION     DAFEML010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.148"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            23..130
                     /locus_tag="LP468_002851"
                     /pseudo
     CDS             23..130
                     /locus_tag="LP468_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            344..1039
                     /gene="vanR"
                     /locus_tag="LP468_002852"
     CDS             344..1039
                     /gene="vanR"
                     /locus_tag="LP468_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2082291.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1017..2171
                     /locus_tag="LP468_002853"
     CDS             1017..2171
                     /locus_tag="LP468_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL2082292.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          748 a          409 c          471 g          596 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca gaaggaaata tgactgtaaa
       61 tcaaatttgt gaaattacta atgtatctag ggcttcatta tacaggaaat tatcagaagt
      121 gaataattag ccattctgta ttccgctaat gggcaatatt tttaaagaag aaaaggaaac
      181 tataaaatat taacagcctc ctagcgatgc cgaaaagccc tttgataaaa aaagaatcat
      241 catcttaaga aattcttagt catttattat gtaaatgctt ataaattcgg ccctataatc
      301 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
      361 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
      421 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
      481 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
      541 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
      601 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
      661 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
      721 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
      781 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
      841 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
      901 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
      961 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
     1021 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
     1081 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
     1141 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
     1201 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
     1261 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
     1321 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
     1381 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
     1441 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
     1501 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
     1561 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
     1621 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
     1681 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
     1741 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
     1801 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
     1861 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
     1921 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
     1981 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
     2041 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
     2101 atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa
     2161 ggaggtccta agagatgtat ataattttgg ctctttgtca aatgatgttg gtaaagagaa
     2221 atct
//
LOCUS       DAFEML010000197         1501 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR29635_1
            SAMN20573733-rid13346383.guided.159, whole genome shotgun sequence.
ACCESSION   DAFEML010000197
VERSION     DAFEML010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573733
            Sequence Read Archive: SRR16917279
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177002.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177002.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:21:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,856
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,723
            CDSs (with protein)               :: 2,723
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 29 of 71
            Pseudo Genes (incomplete)         :: 37 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573733-rid13346383.guided.159"
                     /isolate="PR29635_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-09"
                     /collected_by="University of Michigan"
     gene            110..193
                     /locus_tag="LP468_002854"
     CDS             110..193
                     /locus_tag="LP468_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL2082293.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="LP468_002855"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="LP468_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2082294.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1225..1485
                     /locus_tag="LP468_002856"
                     /pseudo
     CDS             1225..1485
                     /locus_tag="LP468_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          568 a          238 c          253 g          442 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccat tttgtgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac tgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttac agatgtaata
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggagtatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttttaaattt
     1081 ggaaagttac acgttactaa agggaatgga gataaattat tagatatact actgacagct
     1141 tccaagaagc taaagaggtc cctagcgcct acggggaatt tgtatcgata aggggtacaa
     1201 attcccacta agcgctcggg accccttgta ggaaaatgtc ctaagtgtgg caacaatatt
     1261 gtattaaaaa aatcgtttta tggttgttca aattatcctg aatgtaagtt tactttagct
     1321 gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa aagaattact ggagggaaaa
     1381 gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc cctacaatgc cgttgtaaaa
     1441 attggggaaa agggatatat tgattttatc tctttttcaa aataaacatg gggctgaccc
     1501 a
//
